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6355 result(s) for 'general transcription factors vs specific' within BMC Genomics

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  1. RNA sequencing (RNA-seq) is a powerful tool for genome-wide expression profiling of biological samples with the advantage of high-throughput and high resolution. There are many existing algorithms nowadays for...

    Authors: Hung-I Harry Chen, Yuanhang Liu, Yi Zou, Zhao Lai, Devanand Sarkar, Yufei Huang and Yidong Chen
    Citation: BMC Genomics 2015 16(Suppl 7):S14
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 7

  2. Accumulation of protein aggregates are a major hallmark of progressive neurodegenerative disorders such as Parkinson’s disease and Alzheimer’s disease. Transgenic Caenorhabditis elegans nematodes expressing the h...

    Authors: Yiru A. Wang, Basten L. Snoek, Mark G. Sterken, Joost A. G. Riksen, Jana J. Stastna, Jan E. Kammenga and Simon C. Harvey
    Citation: BMC Genomics 2019 20:232
    Content type: Research article Published on:

  3. The ATP-binding cassette (ABC) transporter superfamily is the largest transporter gene family responsible for transporting specific molecules across lipid membranes in all living organisms. In insects, ABC tra...

    Authors: Shumin Liu, Shun Zhou, Ling Tian, Enen Guo, Yunxia Luan, Jianzhen Zhang and Sheng Li
    Citation: BMC Genomics 2011 12:491
    Content type: Research article Published on:

  4. Eukaryotic organisms, like the model yeast S. cerevisiae, have linear chromosomes that facilitate organization and protection of nuclear DNA. A recent work described a stepwise break/repair method that enabled fu...

    Authors: Tyler W. Doughty, Rosemary Yu, Lucy Fang-I Chao, Zhongjun Qin, Verena Siewers and Jens Nielsen
    Citation: BMC Genomics 2021 22:688
    Content type: Research article Published on:

  5. Maritime pine (Pinus pinaster Aiton) grows in a range of different climates in the southwestern Mediterranean region and the existence of a variety of latitudinal ecotypes or provenances is well established. In t...

    Authors: Rafael A. Cañas, Isabel Feito, José Francisco Fuente-Maqueda, Concepción Ávila, Juan Majada and Francisco M. Cánovas
    Citation: BMC Genomics 2015 16:909
    Content type: Research article Published on:

  6. Despite important progress in the field of innate immunity, our understanding of host immune responses to parasitic nematode infections lags behind that of responses to microbes. A limiting factor has been the...

    Authors: Jonathan Vadnal, Ramesh Ratnappan, Melissa Keaney, Eric Kenney, Ioannis Eleftherianos, Damien O’Halloran and John M. Hawdon
    Citation: BMC Genomics 2017 18:8
    Content type: Research article Published on:

  7. Heterochromatin plays an important role in chromosome function and gene regulation. Despite the availability of polytene chromosomes and genome sequence, the heterochromatin of the major malaria vector Anopheles ...

    Authors: Maria V Sharakhova, Phillip George, Irina V Brusentsova, Scotland C Leman, Jeffrey A Bailey, Christopher D Smith and Igor V Sharakhov
    Citation: BMC Genomics 2010 11:459
    Content type: Research article Published on:

  8. Intraspecies copy number variations (CNVs), defined as unbalanced structural variations of specific genomic loci, ≥1 kb in size, are present in the genomes of animals and plants. A growing number of examples i...

    Authors: Agnieszka Zmienko, Anna Samelak-Czajka, Piotr Kozlowski, Maja Szymanska and Marek Figlerowicz
    Citation: BMC Genomics 2016 17:893
    Content type: Research article Published on:

  9. Pre-harvest sprouting (PHS) in wheat can cause substantial reduction in grain yield and end-use quality. Grain color (GC) together with other components affect PHS resistance. Several quantitative trait loci (...

    Authors: Meng Lin, Dadong Zhang, Shubing Liu, Guorong Zhang, Jianming Yu, Allan K. Fritz and Guihua Bai
    Citation: BMC Genomics 2016 17:794
    Content type: Research article Published on:

  10. The Asian corn borer (ACB), Ostrinia furnacalis (Guenée), has become the most damaging insect pest of corn in Asia. However, the lack of genome or transcriptome information heavily hinders our further understandi...

    Authors: Li Cui, Changhui Rui, Daibin Yang, Zhenying Wang and Huizhu Yuan
    Citation: BMC Genomics 2017 18:20
    Content type: Research Article Published on:

  11. Asparagine is a very important nitrogen transport and storage compound in plants due to its high nitrogen/carbon ratio and stability. Asparagine intracellular concentration depends on a balance between asparag...

    Authors: Margarita García-Calderón, Carmen M. Pérez-Delgado, Alfredo Credali, José M. Vega, Marco Betti and Antonio J. Márquez
    Citation: BMC Genomics 2017 18:781
    Content type: Research article Published on:

  12. Benefits from high-throughput sequencing using 454 pyrosequencing technology may be most apparent for species with high societal or economic value but few genomic resources. Rapid means of gene sequence and SN...

    Authors: Evandro Novaes, Derek R Drost, William G Farmerie, Georgios J Pappas Jr, Dario Grattapaglia, Ronald R Sederoff and Matias Kirst
    Citation: BMC Genomics 2008 9:312
    Content type: Research article Published on:

  13. Behavior reflects an organism’s health status. Many organisms display a generalized suite of behaviors that indicate infection or predict infection susceptibility. We apply this concept to honey bee aggression...

    Authors: Clare C. Rittschof, Benjamin E. R. Rubin and Joseph H. Palmer
    Citation: BMC Genomics 2019 20:1029
    Content type: Research article Published on:

  14. Nicotine-degrading microorganisms (NDMs) have recently received much attention since they can consume nicotine as carbon and nitrogen source for growth. In our previous work, we isolated an efficient nicotine-...

    Authors: Chunjuan He, Yougui Huang, Peng Liu, Jianhuan Wei, Yirui Yang, Li Xu and Min Xiao
    Citation: BMC Genomics 2019 20:86
    Content type: Research article Published on:

  15. Autoinflammatory diseases in dogs are characterized by complex disease processes with varying clinical signs. In Shar-Pei, signs of inflammation including fever and arthritis are known to be related with a bre...

    Authors: Julia Metzger, Anna Nolte, Ann-Kathrin Uhde, Marion Hewicker-Trautwein and Ottmar Distl
    Citation: BMC Genomics 2017 18:348
    Content type: Research article Published on:

  16. Nuclear Factor kappa B (NF-κB) is a transcription factor involved in the regulation of cell signaling responses and is a key regulator of cellular processes involved in the immune response, differentiation, ce...

    Authors: Abhinav Grover, Ashutosh Shandilya, Ankita Punetha, Virendra S Bisaria and Durai Sundar
    Citation: BMC Genomics 2010 11(Suppl 4):S25
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 11 Supplement 4

  17. The fungus gardens of leaf-cutting ants are natural biomass conversion systems that turn fresh plant forage into fungal biomass to feed the farming ants. However, the decomposition potential of the symbiont Leuco...

    Authors: Morten N Grell, Tore Linde, Sanne Nygaard, Kåre L Nielsen, Jacobus J Boomsma and Lene Lange
    Citation: BMC Genomics 2013 14:928
    Content type: Research article Published on:

  18. Common bean is a legume of social and nutritional importance as a food crop, cultivated worldwide especially in developing countries, accounting for an important source of income for small farmers. The availab...

    Authors: Paula A. M. R. Valdisser, Wendell J. Pereira, Jâneo E. Almeida Filho, Bárbara S. F. Müller, Gesimária R. C. Coelho, Ivandilson P. P. de Menezes, João P. G. Vianna, Maria I. Zucchi, Anna C. Lanna, Alexandre S. G. Coelho, Jaison P. de Oliveira, Alessandra da Cunha Moraes, Claudio Brondani and Rosana P. Vianello
    Citation: BMC Genomics 2017 18:423
    Content type: Research article Published on:

  19. The plant pathogenic basidiomycete Sclerotium rolfsii produces the industrially exploited exopolysaccharide scleroglucan, a polymer that consists of (1 → 3)-β-linked glucose with a (1 → 6)-β-glycosyl branch on ev...

    Authors: Jochen Schmid, Dirk Müller-Hagen, Thomas Bekel, Laura Funk, Ulf Stahl, Volker Sieber and Vera Meyer
    Citation: BMC Genomics 2010 11:329
    Content type: Research article Published on:

  21. Carotenoids are widely distributed in plants and algae, and their biosynthesis has attracted widespread interest. Carotenoid-related research has mostly focused on model species, and there is a lack of data on...

    Authors: Yuan He, Yafeng Ma, Yu Du and Songdong Shen
    Citation: BMC Genomics 2018 19:916
    Content type: Research article Published on:

  22. The majority of published gene-expression studies have used RNA isolated from whole cells, overlooking the potential impact of including nuclear transcriptome in the analyses. In this study, mRNA fractions fro...

    Authors: Beata Werne Solnestam, Henrik Stranneheim, Jimmie Hällman, Max Käller, Emma Lundberg, Joakim Lundeberg and Pelin Akan
    Citation: BMC Genomics 2012 13:574
    Content type: Research article Published on:

  23. The molluscan Pinctada fucata is an important pearl-culturing organism to study biomineralization mechanisms. Several biomineralization-related genes play important roles regulating shell formation, but most prev...

    Authors: Jun Liu, Dong Yang, Shiting Liu, Shiguo Li, Guangrui Xu, Guilan Zheng, Liping Xie and Rongqing Zhang
    Citation: BMC Genomics 2015 16:325
    Content type: Research article Published on:

  24. Transcriptome analysis of porcine whole blood has several applications, which include deciphering genetic mechanisms for host responses to viral infection and vaccination. The abundance of alpha- and beta-glob...

    Authors: Igseo Choi, Hua Bao, Arun Kommadath, Afshin Hosseini, Xu Sun, Yan Meng, Paul Stothard, Graham S Plastow, Christopher K Tuggle, James M Reecy, Eric Fritz-Waters, Samuel M Abrams, Joan K Lunney and Le Luo Guan
    Citation: BMC Genomics 2014 15:954
    Content type: Methodology article Published on:

  25. The transport of sugars, hormones, amino acids, proteins, sugar alcohols, and other organic compounds from the sites of synthesis to the sites of use or storage occurs through the conducting cells of the phloe...

    Authors: James A Anstead, Steven D Hartson and Gary A Thompson
    Citation: BMC Genomics 2013 14:764
    Content type: Research article Published on:

  26. SWEET (MtN3_saliva) domain proteins, a recently identified group of efflux transporters, play an indispensable role in sugar efflux, phloem loading, plant-pathogen interaction and reproductive tissue development....

    Authors: Gunvant Patil, Babu Valliyodan, Rupesh Deshmukh, Silvas Prince, Bjorn Nicander, Mingzhe Zhao, Humira Sonah, Li Song, Li Lin, Juhi Chaudhary, Yang Liu, Trupti Joshi, Dong Xu and Henry T. Nguyen
    Citation: BMC Genomics 2015 16:520
    Content type: Research article Published on:

  27. The Muscovy duck (Cairina moschata) is an economically important duck species, with favourable growth and carcass composition parameters in comparison to other ducks. However, limited genomic resources for Muscov...

    Authors: Fan Jiang, Yaoxin Jiang, Wenxuan Wang, Changyi Xiao, Ruiyi Lin, Tanghui Xie, Wing-Kin Sung, Shijun Li, Ivan Jakovlić, Jianhai Chen and Xiaoyong Du
    Citation: BMC Genomics 2021 22:581
    Content type: Research Published on:

  29. Waterlily (Nymphaea spp.), a perennial herbaceous aquatic plant, is divided into two ecological groups: hardy waterlily and tropical waterlily. Although the hardy waterlily has no attractive blue flower cultivar,...

    Authors: Qian Wu, Jie Wu, Shan-Shan Li, Hui-Jin Zhang, Cheng-Yong Feng, Dan-Dan Yin, Ru-Yan Wu and Liang-Sheng Wang
    Citation: BMC Genomics 2016 17:897
    Content type: Research article Published on:

  30. RNA interference (RNAi) regulates gene expression in most multicellular organisms through binding of small RNA effectors to target transcripts. Exploiting this process is a popular strategy for genetic manipul...

    Authors: Mosharrof Mondal, Jacob Peter, Obrie Scarbrough and Alex Flynt
    Citation: BMC Genomics 2021 22:42
    Content type: Methodology article Published on:

  31. Intracellular zinc concentration and localization are strictly regulated by two main protein components, metallothioneins and membrane transporters. In mammalian cells, two membrane transporters family are inv...

    Authors: Michel Seve, Fabrice Chimienti, Séverine Devergnas and Alain Favier
    Citation: BMC Genomics 2004 5:32
    Content type: Research article Published on:

  33. Zearalenone (ZEA) is a secondary metabolite produced by Fusarium species. ZEA was proved to exert a wide range of unwanted side effects, but its mechanism of action, particularly at duodenum levels, remains un...

    Authors: Cornelia Braicu, Roxana Cojocneanu-Petric, Ancuta Jurj, Diana Gulei, Ionelia Taranu, Alexandru Mihail Gras, Daniela Eliza Marin and Ioana Berindan-Neagoe
    Citation: BMC Genomics 2016 17:646
    Content type: Research article Published on:

  34. Indigenous populations of animals have developed unique adaptations to their local environments, which may include factors such as response to thermal stress, drought, pathogens and suboptimal nutrition. The s...

    Authors: D. S. Fleming, J. E. Koltes, A. D. Markey, C. J. Schmidt, C. M. Ashwell, M. F. Rothschild, M. E. Persia, J. M. Reecy and S. J. Lamont
    Citation: BMC Genomics 2016 17:407
    Content type: Research article Published on:

  35. Ischemic stroke (IS) is a serious neurological disease that largely results in long-term disability and death. Extensive evidence has indicated that the activation of inflammation and ferroptosis significantly...

    Authors: Jian-Min Chen, Xiao-Lu Li, Yang Ye, Sen-Ming Xu, Qing-Fa Chen and Jian-Wen Xu
    Citation: BMC Genomics 2023 24:67
    Content type: Research Published on:

  36. The freshwater snail Lymnaea stagnalis (L. stagnalis) has served as a successful model for studies in the field of Neuroscience. However, a serious drawback in the molecular analysis of the nervous system of L. s...

    Authors: Z-P Feng, Z Zhang, RE van Kesteren, VA Straub, P van Nierop, K Jin, N Nejatbakhsh, JI Goldberg, GE Spencer, MS Yeoman, W Wildering, JR Coorssen, RP Croll, LT Buck, NI Syed and AB Smit
    Citation: BMC Genomics 2009 10:451
    Content type: Research article Published on:

  37. Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock ...

    Authors: Polyana C Tizioto, Luiz L Coutinho, Jared E Decker, Robert D Schnabel, Kamila O Rosa, Priscila SN Oliveira, Marcela M Souza, Gerson B Mourão, Rymer R Tullio, Amália S Chaves, Dante PD Lanna, Adhemar Zerlotini-Neto, Mauricio A Mudadu, Jeremy F Taylor and Luciana CA Regitano
    Citation: BMC Genomics 2015 16:242
    Content type: Research article Published on:

  39. Cadmium is a persistent pollutant that threatens most biological organisms, including cyanobacteria that support a large part of the biosphere. Using a multifaceted approach, we have investigated the global re...

    Authors: Laetitia Houot, Martin Floutier, Benoit Marteyn, Magali Michaut, Antoine Picciocchi, Pierre Legrain, Jean-Christophe Aude, Corinne Cassier-Chauvat and Franck Chauvat
    Citation: BMC Genomics 2007 8:350
    Content type: Research article Published on:

  40. Cellular senescence is an irreversible cell cycle arrest that normal cells undergo in response to progressive shortening of telomeres, changes in telomeric structure, oncogene activation or oxidative stress an...

    Authors: Emilie Rovillain, Louise Mansfield, Christopher J Lord, Alan Ashworth and Parmjit S Jat
    Citation: BMC Genomics 2011 12:355
    Content type: Research article Published on:

  41. Orang-utans comprise three critically endangered species endemic to the islands of Borneo and Sumatra. Though whole-genome sequencing has recently accelerated our understanding of their evolutionary history, t...

    Authors: Graham L. Banes, Emily D. Fountain, Alyssa Karklus, Hao-Ming Huang, Nian-Hong Jang-Liaw, Daniel L. Burgess, Jennifer Wendt, Cynthia Moehlenkamp and George F. Mayhew
    Citation: BMC Genomics 2020 21:873
    Content type: Research article Published on:

  42. Asthma pathogenesis and susceptibility involves a complex interplay between genetic and environmental factors. Their interaction modulates the airway inflammation and remodelling processes that are present eve...

    Authors: Catherine Laprise, Robert Sladek, André Ponton, Marie-Claude Bernier, Thomas J Hudson and Michel Laviolette
    Citation: BMC Genomics 2004 5:21
    Content type: Methodology article Published on:

  44. The fungal species complex Colletotrichum gloeosporioides sensu lato contains over 20 plant-interacting species. These species exhibit different life styles (e.g., endophytes, foliar and fruit pathogens) and show...

    Authors: Xiaofei Liang, Xianglin Tian, Wenkui Liu, Tingyu Wei, Wei Wang, Qiuyue Dong, Bo Wang, Yanan Meng, Rong Zhang, Mark L. Gleason and Guangyu Sun
    Citation: BMC Genomics 2017 18:171
    Content type: Research article Published on:

  45. The genetic closeness and divergent muscle growth rates of broilers and layers make them great models for myogenesis study. In order to discover the molecular mechanisms determining the divergent muscle growth...

    Authors: Qi Zheng, Yong Zhang, Ying Chen, Ning Yang, Xiu-Jie Wang and Dahai Zhu
    Citation: BMC Genomics 2009 10:87
    Content type: Research article Published on:

  46. Intermittent fasting and time-restricted diets are associated with lower risk biomarkers for cardio-metabolic disease. The shared mechanisms underpinning the similar physiological response to these events is n...

    Authors: Alexessander Couto Alves, Craig A. Glastonbury, Julia S. El-Sayed Moustafa and Kerrin S. Small
    Citation: BMC Genomics 2018 19:659
    Content type: Research article Published on:

  47. The locus Rk confers resistance against several species of root-knot nematodes (Meloidogyne spp., RKN) in cowpea (Vigna unguiculata). Based on histological and reactive oxygen species (ROS) profiles, Rk confers a...

    Authors: Sayan Das, Jeffrey D Ehlers, Timothy J Close and Philip A Roberts
    Citation: BMC Genomics 2010 11:480
    Content type: Research article Published on:

  48. Pseudomonas fluorescens F113 is a plant growth-promoting rhizobacterium (PGPR) isolated from the sugar-beet rhizosphere. This bacterium has been extensively studied as a model strain for genetic regulation of sec...

    Authors: Miguel Redondo-Nieto, Matthieu Barret, John Morrissey, Kieran Germaine, Francisco Martínez-Granero, Emma Barahona, Ana Navazo, María Sánchez-Contreras, Jennifer A Moynihan, Candela Muriel, David Dowling, Fergal O’Gara, Marta Martín and Rafael Rivilla
    Citation: BMC Genomics 2013 14:54
    Content type: Research article Published on:

  49. Variation within individual genomes ranges from single nucleotide polymorphisms (SNPs) to kilobase, and even megabase, sized structural variants (SVs), such as deletions, insertions, inversions, and more compl...

    Authors: Hindrik HD Kerstens, Richard PMA Crooijmans, Bert W Dibbits, Addie Vereijken, Ron Okimoto and Martien AM Groenen
    Citation: BMC Genomics 2011 12:94
    Content type: Methodology article Published on:

  50. Heat stress in poultry results in considerable economic losses and is a concern for both animal health and welfare. Physiological changes occur during periods of heat stress, including changes in blood chemist...

    Authors: Angelica Van Goor, Christopher M. Ashwell, Michael E. Persia, Max F. Rothschild, Carl J. Schmidt and Susan J. Lamont
    Citation: BMC Genomics 2016 17:287
    Content type: Research article Published on:

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