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  1. One of the most important members of the genus Brassica, cabbage, requires a relatively high level of calcium for normal growth (Plant Cell Environ 7: 397–405, 1984; Plant Physiol 60: 854–856, 1977). Localized Ca

    Authors: Jeongyeo Lee, Jungeun Kim, Jae-Pil Choi, MiYe Lee, Min Keun Kim, Young Han Lee, Yoonkang Hur, Ill-Sup Nou, Sang Un Park, Sung Ran Min and HyeRan Kim
    Citation: BMC Genomics 2016 17:211
    Content type: Research article Published on:

  3. Chemical bioavailability is an important dose metric in environmental risk assessment. Although many approaches have been used to evaluate bioavailability, not a single approach is free from limitations. Previ...

    Authors: Ping Gong, Xiaofei Nan, Natalie D. Barker, Robert E. Boyd, Yixin Chen, Dawn E. Wilkins, David R. Johnson, Burton C. Suedel and Edward J. Perkins
    Citation: BMC Genomics 2016 17:205
    Content type: Methodology article Published on:

  4. Across species, diversity at the Major Histocompatibility Complex (MHC) is critical to disease resistance and population health; however, use of MHC diversity to quantify the genetic health of populations has ...

    Authors: Kathleen E. Grogan, Gwendolyn J. McGinnis, Michelle L. Sauther, Frank P. Cuozzo and Christine M. Drea
    Citation: BMC Genomics 2016 17:204
    Content type: Research article Published on:

  5. Asexual reproduction has the potential to enhance deleterious mutation accumulation and to constrain adaptive evolution. One source of mutations that can be especially relevant in recent asexuals is activity o...

    Authors: Julie Ferreira de Carvalho, Carla Oplaat, Nikolaos Pappas, Martijn Derks, Dick de Ridder and Koen J. F. Verhoeven
    Citation: BMC Genomics 2016 17:203
    Content type: Research article Published on:

  6. Colletotrichum graminicola is a hemibiotrophic fungal pathogen that causes maize anthracnose disease. It progresses through three recognizable phases of pathogenic development in plant...

    Authors: Maria F. Torres, Noushin Ghaffari, Ester A. S. Buiate, Neil Moore, Scott Schwartz, Charles D. Johnson and Lisa J. Vaillancourt
    Citation: BMC Genomics 2016 17:202
    Content type: Research article Published on:

  7. C4 photosynthesis evolved from C3 photosynthesis and has higher light, water, and nitrogen use efficiencies. Several C4 photosynthesis genes show cell-specific expression patterns, which are required for these hi...

    Authors: Chensi Cao, Jiajia Xu, Guangyong Zheng and Xin-Guang Zhu
    Citation: BMC Genomics 2016 17:201
    Content type: Research article Published on:

  8. Drought and soil salinity are major abiotic stresses. The mechanisms of stress tolerance have been studied extensively in model plants. Caragana korshinskii is characterized by high drought and salt tolerance in ...

    Authors: Shaofeng Li, Chengming Fan, Yan Li, Jianhui Zhang, Jingshuang Sun, Yuhong Chen, Changyan Tian, Xiaohua Su, Mengzhu Lu, Chengzhi Liang and Zanmin Hu
    Citation: BMC Genomics 2016 17:200
    Content type: Research article Published on:

  9. The initiating nucleotide found at the 5’ end of primary transcripts has a distinctive triphosphorylated end that distinguishes these transcripts from all other RNA species. Recognizing this distinction is key...

    Authors: Laurence Ettwiller, John Buswell, Erbay Yigit and Ira Schildkraut
    Citation: BMC Genomics 2016 17:199
    Content type: Methodology article Published on:

  10. Rhizobium tropici strain CIAT 899 establishes effective symbioses with several legume species, including Phaseolus vulgaris and Leucaena leucocephala. This bacterium synthesizes a larg...

    Authors: Francisco Pérez-Montaño, Pablo del Cerro, Irene Jiménez-Guerrero, Francisco Javier López-Baena, Maria Teresa Cubo, Mariangela Hungria, Manuel Megías and Francisco Javier Ollero
    Citation: BMC Genomics 2016 17:198
    Content type: Research article Published on:

  11. The identification of quantitative trait loci (QTLs) that are stable and consistent across multiple environments and populations plays an essential role in marker-assisted selection (MAS). In the present study...

    Authors: Muhammad Jamshed, Fei Jia, Juwu Gong, Koffi Kibalou Palanga, Yuzhen Shi, Junwen Li, Haihong Shang, Aiying Liu, Tingting Chen, Zhen Zhang, Juan Cai, Qun Ge, Zhi Liu, Quanwei Lu, Xiaoying Deng, Yunna Tan…
    Citation: BMC Genomics 2016 17:197
    Content type: Research article Published on:

  12. A region on Sus scrofa chromosome 4 (SSC4) surrounding single nucleotide polymorphism (SNP) marker WUR10000125 (WUR) has been reported to be strongly associated with both weight gain and serum viremia in pigs aft...

    Authors: Martine Schroyen, Christopher Eisley, James E. Koltes, Eric Fritz-Waters, Igseo Choi, Graham S. Plastow, Leluo Guan, Paul Stothard, Hua Bao, Arun Kommadath, James M. Reecy, Joan K. Lunney, Robert R. R. Rowland, Jack C. M. Dekkers and Christopher K. Tuggle
    Citation: BMC Genomics 2016 17:196
    Content type: Research article Published on:

  13. Sugarcane (Saccharum officinarum L.) is an important sugar crop which belongs to the grass family and can be used for fuel ethanol production. The growing demands for sugar and biofuel is asking for breeding a su...

    Authors: Ming Li, Zhaoxu Liang, Yuan Zeng, Yan Jing, Kaichao Wu, Jun Liang, Shanshan He, Guanyu Wang, Zhanghong Mo, Fang Tan, Song Li and Lunwang Wang
    Citation: BMC Genomics 2016 17:195
    Content type: Research article Published on:

  14. Female reproductive potential plays a significant role in the survival and stability of species, and sexual maturation and mating processes are crucial. However, our knowledge of the reproductive genes involve...

    Authors: Weiwei Zheng, Deye Luo, Fangyu Wu, Jialu Wang and Hongyu Zhang
    Citation: BMC Genomics 2016 17:194
    Content type: Research article Published on:

  16. Phosphorus is one of the most important macronutrients that is required for plant growth and development. However, stress under low-P conditions has become a limiting factor that affects crop yields and qualit...

    Authors: Qing Wang, Jiao Wang, Yuming Yang, Wenkai Du, Dan Zhang, Deyue Yu and Hao Cheng
    Citation: BMC Genomics 2016 17:192
    Content type: Research article Published on:

  17. Soil-borne fungi of the Fusarium oxysporum species complex cause devastating wilt disease on many crops including legumes that supply human dietary protein needs across many parts of the globe. We present and com...

    Authors: Angela H. Williams, Mamta Sharma, Louise F. Thatcher, Sarwar Azam, James K. Hane, Jana Sperschneider, Brendan N. Kidd, Jonathan P. Anderson, Raju Ghosh, Gagan Garg, Judith Lichtenzveig, H. Corby Kistler, Terrance Shea, Sarah Young, Sally-Anne G. Buck, Lars G. Kamphuis…
    Citation: BMC Genomics 2016 17:191
    Content type: Research article Published on:

  18. The ability of Mycobacterium tuberculosis to establish a latent infection (LTBI) in humans confounds the treatment of tuberculosis. Consequently, there is a need to discover new therapeutic agents that can kill M...

    Authors: Andrej Benjak, Swapna Uplekar, Ming Zhang, Jérémie Piton, Stewart T. Cole and Claudia Sala
    Citation: BMC Genomics 2016 17:190
    Content type: Research article Published on:

  19. Nuclear proteins play critical roles in regulating mRNA transcription and processing, DNA replication, and epigenetic genome modification. Therefore, the ability to monitor changes in nuclear proteins is helpf...

    Authors: Xinyou Cao, Xueyan Chen, Yangna Liu, Zhaoshi Xu, Liancheng Li, Yongbin Zhou, Jianjun Liu, Zhendong Zhao, Ming Chen and Youzhi Ma
    Citation: BMC Genomics 2016 17:189
    Content type: Research article Published on:

  20. Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao (A. mongolicus) is an important traditional Chinese herb that is cultivated on a large scale in northwestern China. Understand...

    Authors: Xin Jia, Chuangshu Sun, Yongchun Zuo, Guangyue Li, Guobin Li, Liangyu Ren and Guilin Chen
    Citation: BMC Genomics 2016 17:188
    Content type: Research article Published on:

  21. De novo reference assemblies that are affordable, practical to produce, and of sufficient quality for most downstream applications, remain an unattained goal for many taxa. Insects, wh...

    Authors: R. Rebecca Love, Neil I. Weisenfeld, David B. Jaffe, Nora J. Besansky and Daniel E. Neafsey
    Citation: BMC Genomics 2016 17:187
    Content type: Research article Published on:

  22. Aluminium (Al) toxicity is the main factor limiting the crop production in acid soils and barley (Hordeum vulgare L.) is one of the most Al-sensitive of the small-grained cereals. The major gene for Al tolerance ...

    Authors: Yanling Ma, Chengdao Li, Peter R. Ryan, Sergey Shabala, Jianfeng You, Jie Liu, Chunji Liu and Meixue Zhou
    Citation: BMC Genomics 2016 17:186
    Content type: Research article Published on:

  23. Gene expression is to large degree regulated by the specific binding of protein transcription factors to cis-regulatory transcription factor binding sites in gene promoter regions. Despite the identification o...

    Authors: Monika Lis and Dirk Walther
    Citation: BMC Genomics 2016 17:185
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2016 17:310

  24. Low fertility remains a leading cause of poor productivity in dairy cattle. In this context, there is significant interest in developing novel tools for accurate early diagnosis of pregnancy. MicroRNAs (miRNAs...

    Authors: Jason Ioannidis and F. Xavier Donadeu
    Citation: BMC Genomics 2016 17:184
    Content type: Research article Published on:

  25. The formation of the pre-initiation complex in eukaryotic genes is a key step in transcription initiation. The TATA-binding protein (TBP) is a universal component of all pre-initiation complexes for all kinds ...

    Authors: Natalia Gómez-Navarro, Antonio Jordán-Pla, Francisco Estruch and José E. Pérez-Ortín
    Citation: BMC Genomics 2016 17:183
    Content type: Research article Published on:

  26. The phytoflagellated protozoan, Euglena gracilis, has been proposed as an attractive feedstock for the accumulation of valuable compounds such as β-1,3-glucan, also known as paramylon, and wax esters. The product...

    Authors: Yuta Yoshida, Takuya Tomiyama, Takanori Maruta, Masaru Tomita, Takahiro Ishikawa and Kazuharu Arakawa
    Citation: BMC Genomics 2016 17:182
    Content type: Research article Published on:

  27. Alternative splicing provides a major mechanism to generate protein diversity. Increasing evidence suggests a link of dysregulation of splicing associated with cancer. While previous genomic-based studies demo...

    Authors: Wei Zhao, Katherine A. Hoadley, Joel S. Parker and Charles M. Perou
    Citation: BMC Genomics 2016 17:181
    Content type: Research article Published on:

  28. Clostridium botulinum is a diverse group of bacteria characterized by the production of botulinum neurotoxin. Botulinum neurotoxins are classified into serotypes (BoNT/A–G), which are ...

    Authors: Charles H. D. Williamson, Jason W. Sahl, Theresa J. Smith, Gary Xie, Brian T. Foley, Leonard A. Smith, Rafael A. Fernández, Miia Lindström, Hannu Korkeala, Paul Keim, Jeffrey Foster and Karen Hill
    Citation: BMC Genomics 2016 17:180
    Content type: Research article Published on:

  29. Staphylococcus aureus (S. aureus) infections range in severity due to expression of certain virulence factors encoded on mobile genetic elements (MGE). As such, characterization of the...

    Authors: Richard W. Davis IV, Andrew D. Brannen, Mohammad J. Hossain, Scott Monsma, Paul E. Bock, Matthias Nahrendorf, David Mead, Michael Lodes, Mark R. Liles and Peter Panizzi
    Citation: BMC Genomics 2016 17:179
    Content type: Research article Published on:

  30. Plant architecture attributes, such as plant height, ear height, and internode number, have played an important role in the historical increases in grain yield, lodging resistance, and biomass in maize (Zea mays ...

    Authors: Zhiqiang Zhou, Chaoshu Zhang, Yu Zhou, Zhuanfang Hao, Zhenhua Wang, Xing Zeng, Hong Di, Mingshun Li, Degui Zhang, Hongjun Yong, Shihuang Zhang, Jianfeng Weng and Xinhai Li
    Citation: BMC Genomics 2016 17:178
    Content type: Research article Published on:

  32. For the last decade the conceptual framework of the Genome-Wide Association Study (GWAS) has dominated the investigation of human disease and other complex traits. While GWAS have been successful in identifyin...

    Authors: Matthew P. Salomon, Wai Lok Sibon Li, Christopher K. Edlund, John Morrison, Barbara K. Fortini, Aung Ko Win, David V. Conti, Duncan C. Thomas, David Duggan, Daniel D. Buchanan, Mark A. Jenkins, John L. Hopper, Steven Gallinger, Loïc Le Marchand, Polly A. Newcomb, Graham Casey…
    Citation: BMC Genomics 2016 17:176
    Content type: Research article Published on:

  33. The type-2C protein phosphatases (PP2Cs), negatively regulating ABA responses and MAPK cascade pathways, play important roles in stress signal transduction in plants. Brachypodium distachyon is a new model plant ...

    Authors: Jianmei Cao, Min Jiang, Peng Li and Zhaoqing Chu
    Citation: BMC Genomics 2016 17:175
    Content type: Research article Published on:

  35. The DNA base composition is well known to be highly variable among organisms. Bio-physic studies on the effect of the GC increments on the DNA structure have shown that GC-richer DNA sequences are more bendabl...

    Authors: Andrea Tarallo, Claudia Angelini, Remo Sanges, Mitsuharu Yagi, Claudio Agnisola and Giuseppe D’Onofrio
    Citation: BMC Genomics 2016 17:173
    Content type: Research article Published on:

  36. Aphids are phloem-feeding insects that cause significant economic losses to agriculture worldwide. While feeding and probing these insects deliver molecules, called effectors, inside their host to enable infes...

    Authors: Peter Thorpe, Peter J. A. Cock and Jorunn Bos
    Citation: BMC Genomics 2016 17:172
    Content type: Research article Published on:

  37. The distributions of species and their responses to climate change are in part determined by their thermal tolerances. However, little is known about how thermal tolerance evolves. To test whether evolutionary...

    Authors: John Stanton-Geddes, Andrew Nguyen, Lacy Chick, James Vincent, Mahesh Vangala, Robert R. Dunn, Aaron M. Ellison, Nathan J. Sanders, Nicholas J. Gotelli and Sara Helms Cahan
    Citation: BMC Genomics 2016 17:171
    Content type: Research article Published on:

  38. Exome sequencing has been utilized to identify genetic variants associated with disease in humans. Identification of loss-of-function mutations with exome sequencing in rhesus macaques (Macaca mulatta) could lead...

    Authors: Adam S. Cornish, Robert M. Gibbs and Robert B. Norgren Jr.
    Citation: BMC Genomics 2016 17:170
    Content type: Research article Published on:

  41. The Major Histocompatibility Complex (MHC) is a genomic region containing genes with crucial roles in immune responses. MHC class I and class II genes encode antigen-presenting molecules expressed on the cell ...

    Authors: Martin Plasil, Elmira Mohandesan, Robert R. Fitak, Petra Musilova, Svatava Kubickova, Pamela A. Burger and Petr Horin
    Citation: BMC Genomics 2016 17:167
    Content type: Research article Published on:

  42. Nematodes are the most numerous animals in the soil. Insect parasitic nematodes of the genus Heterorhabditis are capable of selectively seeking, infecting and killing their insect-hosts in the soil. The infective...

    Authors: Vishal S. Somvanshi, Shachi Gahoi, Prakash Banakar, Prasoon Kumar Thakur, Mukesh Kumar, Manisha Sajnani, Priyatama Pandey and Uma Rao
    Citation: BMC Genomics 2016 17:166
    Content type: Research article Published on:

  43. Bioinformatics tools available for metagenomic sequencing analysis are principally devoted to the identification of microorganisms populating an ecological niche, but they usually do not consider viruses. Only...

    Authors: Simone Rampelli, Matteo Soverini, Silvia Turroni, Sara Quercia, Elena Biagi, Patrizia Brigidi and Marco Candela
    Citation: BMC Genomics 2016 17:165
    Content type: Software Published on:

  44. MicroRNAs (miRNAs) have emerged as important post-transcriptional regulators of gene expression in a wide variety of physiological processes. They can control both temporal and spatial gene expression and are ...

    Authors: Amelie Juanchich, Philippe Bardou, Olivier Rué, Jean-Charles Gabillard, Christine Gaspin, Julien Bobe and Yann Guiguen
    Citation: BMC Genomics 2016 17:164
    Content type: Research article Published on:

  45. Restricted and Repetitive Behaviors (RRB), one of the core symptom categories for Autism Spectrum Disorders (ASD), comprises heterogeneous groups of behaviors. Previous research indicates that there are two or...

    Authors: Yu Tao, Hui Gao, Benjamin Ackerman, Wei Guo, David Saffen and Yin Yao Shugart
    Citation: BMC Genomics 2016 17:163
    Content type: Research article Published on:

  46. The nuclear orphan receptor Nur77 (NR4A1, TR3, or NGFI-B) has been shown to modulate the inflammatory response of macrophages. To further elucidate the role of Nur77 in macrophage physiology, we compared the t...

    Authors: Anouk A. J. Hamers, Carmen Argmann, Perry D. Moerland, Duco S. Koenis, Goran Marinković, Milka Sokolović, Alex F. de Vos, Carlie J. M. de Vries and Claudia M. van Tiel
    Citation: BMC Genomics 2016 17:162
    Content type: Research article Published on:

  47. The clawed African frog Xenopus laevis has been one of the main vertebrate models for studies in developmental biology. However, for genetic studies, Xenopus tropicalis has been the experimental model of choice b...

    Authors: Gonzalo Riadi, Francisco Ossandón, Juan Larraín and Francisco Melo
    Citation: BMC Genomics 2016 17:161
    Content type: Research article Published on:

  48. Copper dependent nitrite reductase, NirK, catalyses the key step in denitrification, i.e. nitrite reduction to nitric oxide. Distinct structural NirK classes and phylogenetic clades of NirK-type denitrifiers h...

    Authors: Decleyre Helen, Heylen Kim, Bjorn Tytgat and Willems Anne
    Citation: BMC Genomics 2016 17:155
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2016 17:527

  49. Non-coding RNAs (ncRNAs), which perform diverse regulatory roles, have been found in organisms from all superkingdoms of life. However, there have been limited numbers of studies on the functions of ncRNAs, es...

    Authors: Yoo-Bok Cho, Eun Ju Lee, Suhyung Cho, Tae Yong Kim, Jin Hwan Park and Byung-Kwan Cho
    Citation: BMC Genomics 2016 17:154
    Content type: Research article Published on:

  50. The root architecture of grafted apple (Malus spp.) is affected by various characteristics of the scions. To provide information on the molecular mechanisms underlying this influence, we examined root transcripto...

    Authors: Guofang Li, Juanjuan Ma, Ming Tan, Jiangping Mao, Na An, Guangli Sha, Dong Zhang, Caiping Zhao and Mingyu Han
    Citation: BMC Genomics 2016 17:150
    Content type: Research article Published on:

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BMC Genomics

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