Skip to main content

Articles

Page 208 of 337

  1. Nucleomorphs are residual nuclei derived from eukaryotic endosymbionts in chlorarachniophyte and cryptophyte algae. The endosymbionts that gave rise to nucleomorphs and plastids in these two algal groups were ...

    Authors: Goro Tanifuji, Naoko T Onodera, Matthew W Brown, Bruce A Curtis, Andrew J Roger, Gane Ka-Shu Wong, Michael Melkonian and John M Archibald
    Citation: BMC Genomics 2014 15:374
    Content type: Research article Published on:

  2. As the architecture of complex traits incorporates a widening spectrum of genetic variation, analyses integrating common and rare variation are needed. Body mass index (BMI) represents a model trait, since com...

    Authors: Roseann E Peterson, Hermine H Maes, Peng Lin, John R Kramer, Victor M Hesselbrock, Lance O Bauer, John I Nurnberger Jr, Howard J Edenberg, Danielle M Dick and Bradley T Webb
    Citation: BMC Genomics 2014 15:368
    Content type: Research article Published on:

  3. Transgenesis by random integration of a transgene into the genome of a zygote has become a reliable and powerful method for the creation of new mouse strains that express exogenous genes, including human disea...

    Authors: Anuj Srivastava, Vivek M Philip, Ian Greenstein, Lucy B Rowe, Mary Barter, Cathleen Lutz and Laura G Reinholdt
    Citation: BMC Genomics 2014 15:367
    Content type: Methodology article Published on:

  4. Alternative splicing diversifies the pool of messenger RNA molecules encoded by individual genes. This diversity is particularly high when multiple splicing decisions cause a combinatorial arrangement of sever...

    Authors: Dominique A Glauser
    Citation: BMC Genomics 2014 15:364
    Content type: Research article Published on:

  5. Amycolatopsis orientalis is the type species of the genus and its industrial strain HCCB10007, derived from ATCC 43491, has been used for large-scale production of the vital antibiotic vancomycin. However, to dat...

    Authors: Li Xu, He Huang, Wei Wei, Yi Zhong, Biao Tang, Hua Yuan, Li Zhu, Weiyi Huang, Mei Ge, Shen Yang, Huajun Zheng, Weihong Jiang, Daijie Chen, Guo-Ping Zhao and Wei Zhao
    Citation: BMC Genomics 2014 15:363
    Content type: Research article Published on:

  6. Carolacton is a newly identified secondary metabolite causing altered cell morphology and death of Streptococcus mutans biofilm cells. To unravel key regulators mediating these effects, the transcriptional regula...

    Authors: Padhmanand Sudhakar, Michael Reck, Wei Wang, Feng Q He, Irene W Dobler and An-Ping Zeng
    Citation: BMC Genomics 2014 15:362
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2014 15:739

  7. Essential genes are critical for the development of all organisms and are associated with many human diseases. These genes have been a difficult category to study prior to the availability of balanced lethal s...

    Authors: Jeffrey Shih-Chieh Chu, Shu-Yi Chua, Kathy Wong, Ann Marie Davison, Robert Johnsen, David L Baillie and Ann M Rose
    Citation: BMC Genomics 2014 15:361
    Content type: Research article Published on:

  8. Studies have shown the strong association between histone modification levels and gene expression levels. The detailed relationships between the two can vary substantially due to differential regulation, and h...

    Authors: Yeonok Lee, Debashis Ghosh and Yu Zhang
    Citation: BMC Genomics 2014 15:360
    Content type: Methodology article Published on:

  12. In silico, secretome proteins can be predicted from completely sequenced genomes using various available algorithms that identify membrane-targeting sequences. For metasecretome (collection of surface, secreted a...

    Authors: Milica Ciric, Christina D Moon, Sinead C Leahy, Christopher J Creevey, Eric Altermann, Graeme T Attwood, Jasna Rakonjac and Dragana Gagic
    Citation: BMC Genomics 2014 15:356
    Content type: Methodology article Published on:

  13. Shigella dysenteriae type 1 (Sd1) causes recurrent epidemics of dysentery associated with high mortality in many regions of the world. Sd1 infects humans at very low infectious doses (10 CFU), and treatment is co...

    Authors: Laurence Rohmer, Michael A Jacobs, Mitchell J Brittnacher, Christine Fong, Hillary S Hayden, Didier Hocquet, Eli J Weiss, Matthew Radey, Yves Germani, Kaisar Ali Talukder, Anthony J Hager, John M Kemner, Elizabeth H Sims-Day, Susana Matamouros, Kyle R Hager and Samuel I Miller
    Citation: BMC Genomics 2014 15:355
    Content type: Research article Published on:

  14. Next generation sequencing is helping to overcome limitations in organisms less accessible to classical or reverse genetic methods by facilitating whole genome mutational analysis studies. One traditionally in...

    Authors: Andrew Farrell, Bradley I Coleman, Brian Benenati, Kevin M Brown, Ira J Blader, Gabor T Marth and Marc-Jan Gubbels
    Citation: BMC Genomics 2014 15:354
    Content type: Research article Published on:

  15. Multiple infection sources for enterohemorrhagic Escherichia coli O157:H7 (EHEC) are known, including animal products, fruit and vegetables. The ecology of this pathogen outside its human host is largely unknown ...

    Authors: Richard Landstorfer, Svenja Simon, Steffen Schober, Daniel Keim, Siegfried Scherer and Klaus Neuhaus
    Citation: BMC Genomics 2014 15:353
    Content type: Research article Published on:

  16. Although more than one thousand complete mitochondrial DNA (mtDNA) sequences have been determined in teleostean fishes, only a few gene rearrangements have been observed, and genome-scale rearrangements are ev...

    Authors: Wei Shi, Xian-Guang Miao and Xiao-Yu Kong
    Citation: BMC Genomics 2014 15:352
    Content type: Research article Published on:

  17. Cultivated peanut, or groundnut (Arachis hypogaea L.), is an important oilseed crop with an allotetraploid genome (AABB, 2n = 4x = 40). In recent years, many efforts have been made to construct linkage maps in cu...

    Authors: Xiaojing Zhou, Youlin Xia, Xiaoping Ren, Yulin Chen, Li Huang, Shunmou Huang, Boshou Liao, Yong Lei, Liyin Yan and Huifang Jiang
    Citation: BMC Genomics 2014 15:351
    Content type: Research article Published on:

  18. Considerable work has been carried out to understand the biology of tachyzoites and bradyzoites of Toxoplasma gondii in large part due to in vitro culture methods for these stages. However, culturing methods for ...

    Authors: Michael S Behnke, Tiange P Zhang, Jitender P Dubey and L David Sibley
    Citation: BMC Genomics 2014 15:350
    Content type: Research article Published on:

  19. Bacterial interactions with the environment- and/or host largely depend on the bacterial glycome. The specificities of a bacterial glycome are largely determined by glycosyltransferases (GTs), the enzymes invo...

    Authors: Aminael Sánchez-Rodríguez, Hanne LP Tytgat, Joris Winderickx, Jos Vanderleyden, Sarah Lebeer and Kathleen Marchal
    Citation: BMC Genomics 2014 15:349
    Content type: Research article Published on:

  20. Deep-sequencing has enabled the identification of large numbers of miRNAs and siRNAs, making the high-throughput target identification a main limiting factor in defining their function. In plants, several tool...

    Authors: Prashant K Srivastava, Taraka Ramji Moturu, Priyanka Pandey, Ian T Baldwin and Shree P Pandey
    Citation: BMC Genomics 2014 15:348
    Content type: Research article Published on:

  21. In eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors. The human malaria parasite Plasmodium falciparum encodes relative...

    Authors: Evelien M Bunnik, Anton Polishko, Jacques Prudhomme, Nadia Ponts, Sarjeet S Gill, Stefano Lonardi and Karine G Le Roch
    Citation: BMC Genomics 2014 15:347
    Content type: Research article Published on:

  22. High-yielding cultivars of rice (Oryza sativa L.) have been developed in Japan from crosses between overseas indica and domestic japonica cultivars. Recently, next-generation sequencing technology and high-throug...

    Authors: Jun-ichi Yonemaru, Ritsuko Mizobuchi, Hiroshi Kato, Toshio Yamamoto, Eiji Yamamoto, Kazuki Matsubara, Hideyuki Hirabayashi, Yoshinobu Takeuchi, Hiroshi Tsunematsu, Takuro Ishii, Hisatoshi Ohta, Hideo Maeda, Kaworu Ebana and Masahiro Yano
    Citation: BMC Genomics 2014 15:346
    Content type: Research article Published on:

  23. Opioids are the cornerstone of treatment for moderate to severe pain, but chronic use leads to maladaptations that include: tolerance, dependence and opioid-induced hyperalgesia (OIH). These responses limit th...

    Authors: De-Yong Liang, Ming Zheng, Yuan Sun, Peyman Sahbaie, Sarah A Low, Gary Peltz, Grégory Scherrer, Cecilia Flores and J David Clark
    Citation: BMC Genomics 2014 15:345
    Content type: Research article Published on:

  24. Heat shock proteins (Hsps) perform a fundamental role in protecting plants against abiotic stresses. Although researchers have made great efforts on the functional analysis of individual family members, Hsps h...

    Authors: Yongfei Wang, Shoukai Lin, Qi Song, Kuan Li, Huan Tao, Jian Huang, Xinhai Chen, Shufu Que and Huaqin He
    Citation: BMC Genomics 2014 15:344
    Content type: Research article Published on:

  26. Endoparasitoid wasps are important natural enemies of the widely distributed aphid pests and are mainly used as biological control agents. However, despite the increased interest on aphid interaction networks,...

    Authors: Dominique Colinet, Caroline Anselme, Emeline Deleury, Donato Mancini, Julie Poulain, Carole Azéma-Dossat, Maya Belghazi, Sophie Tares, Francesco Pennacchio, Marylène Poirié and Jean-Luc Gatti
    Citation: BMC Genomics 2014 15:342
    Content type: Research article Published on:

  27. Next Generation Sequencing technologies have facilitated differential gene expression analysis through RNA-seq and Tag-seq methods. RNA-seq has biases associated with transcript lengths, lacks uniform coverage...

    Authors: Ghanasyam Rallapalli, Eric M Kemen, Alexandre Robert-Seilaniantz, Cécile Segonzac, Graham J Etherington, Kee Hoon Sohn, Daniel MacLean and Jonathan D G Jones
    Citation: BMC Genomics 2014 15:341
    Content type: Methodology article Published on:

  28. Hepatitis Delta Virus (HDV)-like ribozymes have recently been found in many mobile elements in which they take part in a mechanism that releases intermediate RNAs from cellular co-transcripts. L1Tc in Trypanosoma...

    Authors: Francisco José Sánchez-Luque, Manuel Carlos López, Patricia Eugenia Carreira, Carlos Alonso and María Carmen Thomas
    Citation: BMC Genomics 2014 15:340
    Content type: Research article Published on:

  29. Superior kidding rate is an important economic trait in production of meat goat, and ovulation rate is the precondition of kidding rate. MicroRNAs (miRNAs) play critical roles in almost all ovarian biological ...

    Authors: Ying-Hui Ling, Chun-Huan Ren, Xiao-Fei Guo, Li-Na Xu, Ya-Feng Huang, Jian-Chuan Luo, Yun-Hai Zhang, Xiao-Rong Zhang and Zi-Jun Zhang
    Citation: BMC Genomics 2014 15:339
    Content type: Research article Published on:

  30. Mendelian disorders are mostly caused by single mutations in the DNA sequence of a gene, leading to a phenotype with pathologic consequences. Whole Exome Sequencing of patients can be a cost-effective alternat...

    Authors: Margherita Mutarelli, Veer Singh Marwah, Rossella Rispoli, Diego Carrella, Gopuraja Dharmalingam, Gennaro Oliva and Diego di Bernardo
    Citation: BMC Genomics 2014 15(Suppl 3):S5
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  31. MicroRNAs (miRNAs) are small noncoding RNAs that play an important role in the regulation of various biological processes through their interaction with cellular mRNAs. A significant amount of miRNAs has been ...

    Authors: Francesco Russo, Sebastiano Di Bella, Vincenzo Bonnici, Alessandro Laganà, Giuseppe Rainaldi, Marco Pellegrini, Alfredo Pulvirenti, Rosalba Giugno and Alfredo Ferro
    Citation: BMC Genomics 2014 15(Suppl 3):S4
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  32. Molecular biology laboratories require extensive metadata to improve data collection and analysis. The heterogeneity of the collected metadata grows as research is evolving in to international multi-disciplina...

    Authors: Massimiliano Izzo, Francesco Mortola, Gabriele Arnulfo, Marco M Fato and Luigi Varesio
    Citation: BMC Genomics 2014 15(Suppl 3):S3
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  33. Whole Exome Sequencing (WES) is one of the most used and cost-effective next generation technologies that allows sequencing of all nuclear exons. Off-target regions may be captured if they present high sequenc...

    Authors: Maria Angela Diroma, Claudia Calabrese, Domenico Simone, Mariangela Santorsola, Francesco Maria Calabrese, Giuseppe Gasparre and Marcella Attimonelli
    Citation: BMC Genomics 2014 15(Suppl 3):S2
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  34. Non-small cell lung cancer (NSCLC) accounts for 81% of all cases of lung cancer and they are often fatal because 60% of the patients are diagnosed at an advanced stage. Besides the need for earlier diagnosis, ...

    Authors: Federica Riccardo, Maddalena Arigoni, Genny Buson, Elisa Zago, Manuela Iezzi, Dario Livio Longo, Matteo Carrara, Alessandra Fiore, Simona Nuzzo, Silvio Bicciato, Patrizia Nanni, Lorena Landuzzi, Federica Cavallo, Raffaele Calogero and Elena Quaglino
    Citation: BMC Genomics 2014 15(Suppl 3):S1
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  35. Bidirectional gene pairs exist as a specific form of gene organization in microorganisms and mammals as well as in model plant species, such as Arabidopsis and rice. Little is known about bidirectional gene pairs...

    Authors: Xiaoqing Liu, Xiaojin Zhou, Ye Li, Jian Tian, Qiuxue Zhang, Suzhen Li, Lei Wang, Jun Zhao, Rumei Chen and Yunliu Fan
    Citation: BMC Genomics 2014 15:338
    Content type: Research article Published on:

  36. Nephrotoxicity is the most prominent one among the various toxicities of ochratoxin A (OTA). MicroRNAs (miRNAs) are small non-coding RNAs that have an impact on a wide range of biological processes by regulati...

    Authors: Qiu Dai, Jue Zhao, Xiaozhe Qi, Wentao Xu, Xiaoyun He, Mingzhang Guo, Harsh Dweep, Wen-Hsing Cheng, Yunbo Luo, Kai Xia, Norbert Gretz and Kunlun Huang
    Citation: BMC Genomics 2014 15:333
    Content type: Research article Published on:

  37. Populus euphratica Oliv and P. pruinosa Schrenk (Salicaceae) both grow in dry desert areas with high summer temperatures. However, P. euphratica is distributed in dry deserts with deep underground water whereas P...

    Authors: Jian Zhang, Jianju Feng, Jing Lu, Yongzhi Yang, Xu Zhang, Dongshi Wan and Jianquan Liu
    Citation: BMC Genomics 2014 15:337
    Content type: Research article Published on:

  38. The white mold fungus Sclerotinia sclerotiorum is a devastating necrotrophic plant pathogen with a remarkably broad host range. The interaction of necrotrophs with their hosts is more complex than initially thoug...

    Authors: Koanna Guyon, Claudine Balagué, Dominique Roby and Sylvain Raffaele
    Citation: BMC Genomics 2014 15:336
    Content type: Research article Published on:

  40. Tomato (Solanum lycopersicum), one of the world’s most important vegetable crops, is highly susceptible to necrotrophic fungal pathogens such as Botrytis cinerea and Alternaria solani. Improving resistance throug...

    Authors: Jonathon E Smith, Bemnet Mengesha, Hua Tang, Tesfaye Mengiste and Burton H Bluhm
    Citation: BMC Genomics 2014 15:334
    Content type: Research article Published on:

  41. The HUGO Pan-Asian SNP Consortium (PASNP) has generated a genetic resource of almost 55,000 autosomal single nucleotide polymorphisms (SNPs) across more than 1,800 individuals from 73 urban and indigenous popu...

    Authors: Xuanyao Liu, Woei-Yuh Saw, Mohammad Ali, Rick Twee-Hee Ong and Yik-Ying Teo
    Citation: BMC Genomics 2014 15:332
    Content type: Research article Published on:

  42. The precise nature of how cell type specific chromatin structures at enhancer sites affect gene expression is largely unknown. Here we identified cell type specific enhancers coupled with gene expression in tw...

    Authors: Suhn Kyong Rhie, Dennis J Hazelett, Simon G Coetzee, Chunli Yan, Houtan Noushmehr and Gerhard A Coetzee
    Citation: BMC Genomics 2014 15:331
    Content type: Research article Published on:

  44. Intrachromosomal segmental duplications provide the substrate for non-allelic homologous recombination, facilitating extensive copy number variation in the human genome. Many multi-copy gene families are embed...

    Authors: Stuart Cantsilieris, Patrick S Western, Paul N Baird and Stefan J White
    Citation: BMC Genomics 2014 15:329
    Content type: Research article Published on:

  45. Heat-induced browning (Hbs) of seed coats is caused by high temperatures which discolors the seed coats of many legumes, affecting the visual appearance and quality of seeds. The genetic determinants underlying H...

    Authors: Marti Pottorff, Philip A Roberts, Timothy J Close, Stefano Lonardi, Steve Wanamaker and Jeffrey D Ehlers
    Citation: BMC Genomics 2014 15:328
    Content type: Research article Published on:

  46. It is believed that the main factors of low prenatal growth in mammals are genetic and environmental. We used isogenic mice maintained in standard conditions to analyze how natural non-genetic microsomia (low ...

    Authors: Alberto Miranda, Angela P López-Cardona, Ricardo Laguna-Barraza, Alexandra Calle, Irene López-Vidriero, Belén Pintado and Alfonso Gutiérrez-Adán
    Citation: BMC Genomics 2014 15:327
    Content type: Research article Published on:

  47. Compared with other Populus species, Populus euphratica Oliv. exhibits better tolerance to abiotic stress, especially those involving extreme temperatures. However, little is known about gene regulation and signa...

    Authors: Jinhuan Chen, Qianqian Tian, Tao Pang, Libo Jiang, Rongling Wu, Xinli Xia and Weilun Yin
    Citation: BMC Genomics 2014 15:326
    Content type: Research article Published on:

  49. Verticillium dahliae is a soil-borne fungus that causes vascular wilt diseases in a wide range of plant hosts. V. dahliae produces multicelled, melanized resting bodies, also known as microsclerotia (MS) that can...

    Authors: Dianguang Xiong, Yonglin Wang, Jie Ma, Steven J Klosterman, Shuxiao Xiao and Chengming Tian
    Citation: BMC Genomics 2014 15:324
    Content type: Research article Published on:

  50. Efficient light acclimation of photosynthetic cells is a basic and important property of plants. The process of acclimation depends on transformation of retrograde signals in gene expression, transcript accumu...

    Authors: Marie-Luise Oelze, Meenakumari Muthuramalingam, Marc Oliver Vogel and Karl-Josef Dietz
    Citation: BMC Genomics 2014 15:320
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • 2022 Citation Impact
    4.4 - 2-year Impact Factor
    4.7 - 5-year Impact Factor
    1.189 - SNIP (Source Normalized Impact per Paper)
    1.107 - SJR (SCImago Journal Rank)

    2023 Speed
    23 days submission to first editorial decision for all manuscripts (Median)
    137 days submission to accept (Median)

    2023 Usage
    7,167,242 downloads
    4,454 Altmetric mentions

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us