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  2. Caligid copepods, also called sea lice, are fish ectoparasites, some species of which cause significant problems in the mariculture of salmon, where the annual cost of infection is in excess of €300 million gl...

    Authors: Stephen N Carmichael, James E Bron, John B Taggart, Jacqueline H Ireland, Michaël Bekaert, Stewart TG Burgess, Philip J Skuce, Alasdair J Nisbet, Karim Gharbi and Armin Sturm
    Citation: BMC Genomics 2013 14:408
    Content type: Research article Published on:

  3. Sturgeons are a group of Condrostean fish with very high evolutionary, economical and conservation interest. The eggs of these living fossils represent one of the most high prized foods of animal origin. The i...

    Authors: Michele Vidotto, Alessandro Grapputo, Elisa Boscari, Federica Barbisan, Alessandro Coppe, Gilberto Grandi, Abhishek Kumar and Leonardo Congiu
    Citation: BMC Genomics 2013 14:407
    Content type: Research article Published on:

  4. It was recently established that changes in methylation during development are dynamic and involve both methylation and demethylation processes. Yet, which genomic sites are changing and what are the contribut...

    Authors: Béatrice de Montera, Eric Fournier, Habib Allah Shojaei Saadi, Dominic Gagné, Isabelle Laflamme, Patrick Blondin, Marc-André Sirard and Claude Robert
    Citation: BMC Genomics 2013 14:406
    Content type: Research article Published on:

  5. Tuberculosis remains a major public health problem. Clinical tuberculosis manifests often as pulmonary and occasionally as extra-pulmonary tuberculosis. The emergence of drug resistant tubercle bacilli and its as...

    Authors: Sarbashis Das, Tanmoy Roychowdhury, Parameet Kumar, Anil Kumar, Priya Kalra, Jitendra Singh, Sarman Singh, HK Prasad and Alok Bhattacharya
    Citation: BMC Genomics 2013 14:404
    Content type: Research article Published on:

  6. Cotton fiber length is very important to the quality of textiles. Understanding the genetics and physiology of cotton fiber elongation can provide valuable tools to the cotton industry by targeting genes or ot...

    Authors: Matthew K Gilbert, Rickie B Turley, Hee Jin Kim, Ping Li, Gregory Thyssen, Yuhong Tang, Christopher D Delhom, Marina Naoumkina and David D Fang
    Citation: BMC Genomics 2013 14:403
    Content type: Research article Published on:

  8. The whiteflies under the name Bemisia tabaci (Gennadius) (Aleyrodidae: Hemiptera) are species complex of at least 31 cryptic species some of which are globally invasive agricultural pests. Previously, the mitocho...

    Authors: Hua-Ling Wang, Jiao Yang, Laura M Boykin, Qiong-Yi Zhao, Qian Li, Xiao-Wei Wang and Shu-Sheng Liu
    Citation: BMC Genomics 2013 14:401
    Content type: Research article Published on:

  9. As a step towards understanding coral immunity we present the first whole transcriptome analysis of the acute responses of Acropora millepora to challenge with the bacterial cell wall derivative MDP and the viral...

    Authors: Yvonne Weiss, Sylvain Forêt, David C Hayward, Tracy Ainsworth, Rob King, Eldon E Ball and David J Miller
    Citation: BMC Genomics 2013 14:400
    Content type: Research article Published on:

  10. In the model organism Saccharomyces cerevisiae, the transposable elements (TEs) consist of LTR (Long Terminal Repeat) retrotransposons called Ty elements belonging to five families, Ty1 to Ty5. They take the form...

    Authors: Claudine Bleykasten-Grosshans, Anne Friedrich and Joseph Schacherer
    Citation: BMC Genomics 2013 14:399
    Content type: Research article Published on:

  11. Detecting genetic variation is a critical step in elucidating the molecular mechanisms underlying phenotypic diversity. Until recently, such detection has mostly focused on single nucleotide polymorphisms (SNP...

    Authors: Richard PMA Crooijmans, Mark S Fife, Tomas W Fitzgerald, Shurnevia Strickland, Hans H Cheng, Pete Kaiser, Richard Redon and Martien AM Groenen
    Citation: BMC Genomics 2013 14:398
    Content type: Research article Published on:

  12. Visualization plays an essential role in genomics research by making it possible to observe correlations and trends in large datasets as well as communicate findings to others. Visual analysis, which combines ...

    Authors: Jeremy Goecks, Carl Eberhard, Tomithy Too, Anton Nekrutenko and James Taylor
    Citation: BMC Genomics 2013 14:397
    Content type: Software Published on:

  13. Arachidonic acid (ArA) is important for human health because it is one of the major components of mammalian brain membrane phospholipids. The interest in ArA inspired the search for a new sustainable source, a...

    Authors: Long-Ling Ouyang, Si-Hong Chen, Yan Li and Zhi-Gang Zhou
    Citation: BMC Genomics 2013 14:396
    Content type: Research article Published on:

  14. Recent studies have illuminated the diversity of roles for microRNAs in cellular, developmental, and pathophysiological processes. The study of microRNAs in human liver tissue promises to clarify the therapeut...

    Authors: Eric R Gamazon, Federico Innocenti, Rongrong Wei, Libo Wang, Min Zhang, Snezana Mirkov, Jacqueline Ramírez, R Stephanie Huang, Nancy J Cox, Mark J Ratain and Wanqing Liu
    Citation: BMC Genomics 2013 14:395
    Content type: Research article Published on:

  15. Snake venoms generally show sequence and quantitative variation within and between species, but some rattlesnakes have undergone exceptionally rapid, dramatic shifts in the composition, lethality, and pharmaco...

    Authors: Darin R Rokyta, Kenneth P Wray and Mark J Margres
    Citation: BMC Genomics 2013 14:394
    Content type: Research article Published on:

  16. Understanding the genetic architecture of quantitative traits is important for developing genome-based crop improvement methods. Genome-wide association study (GWAS) is a powerful technique for mining novel fu...

    Authors: Satish Kumar, Dorian J Garrick, Marco CAM Bink, Claire Whitworth, David Chagné and Richard K Volz
    Citation: BMC Genomics 2013 14:393
    Content type: Research article Published on:

  17. Eukaryotic mitogen-activated protein kinase (MAPK/MPK) signaling cascades transduce and amplify environmental signals via three types of reversibly phosphorylated kinases to activate defense gene expression. C...

    Authors: Wanwan Liang, Bo Yang, Bao-Jun Yu, Zili Zhou, Cui Li, Ming Jia, Yun Sun, Yue Zhang, Feifei Wu, Hanfeng Zhang, Boya Wang, Michael K Deyholos and Yuan-Qing Jiang
    Citation: BMC Genomics 2013 14:392
    Content type: Research article Published on:

  18. Histone wrapping of DNA into nucleosomes almost certainly evolved in the Archaea, and predates Eukaryotes. In Eukaryotes, nucleosome positioning plays a central role in regulating gene expression and is direct...

    Authors: Narasimharao Nalabothula, Liqun Xi, Sucharita Bhattacharyya, Jonathan Widom, Ji-Ping Wang, John N Reeve, Thomas J Santangelo and Yvonne N Fondufe-Mittendorf
    Citation: BMC Genomics 2013 14:391
    Content type: Research article Published on:

  19. Elucidating the biogeography of bacterial communities on the human body is critical for establishing healthy baselines from which to detect differences associated with disease; however, little is known about t...

    Authors: Zongxin Ling, Xia Liu, Yueqiu Luo, Li Yuan, Karen E Nelson, Yuezhu Wang, Charlie Xiang and Lanjuan Li
    Citation: BMC Genomics 2013 14:390
    Content type: Research article Published on:

  20. Previous molecular genetic studies of physiology and pigmentation of sheep skin have focused primarily on a limited number of genes and proteins. To identify additional genes that may play important roles in c...

    Authors: Ruiwen Fan, Jianshan Xie, Junming Bai, Haidong Wang, Xue Tian, Rui Bai, Xiaoyun Jia, Lei Yang, Yunfei Song, Muren Herrid, Wenjun Gao, Xiaoyan He, Jianbo Yao, George W Smith and Changsheng Dong
    Citation: BMC Genomics 2013 14:389
    Content type: Research article Published on:

  21. White clover (Trifolium repens L.) is a temperate forage legume with an allotetraploid genome (2n=4×=32) estimated at 1093 Mb. Several linkage maps of various sizes, marker sources and completeness are available,...

    Authors: Andrew G Griffiths, Brent A Barrett, Deborah Simon, Anar K Khan, Paul Bickerstaff, Craig B Anderson, Benjamin K Franzmayr, Kerry R Hancock and Chris S Jones
    Citation: BMC Genomics 2013 14:388
    Content type: Research article Published on:

  22. Comparative genomics is a powerful tool to transfer genomic information from model species to related non-model species. Channel catfish (Ictalurus punctatus) is the primary aquaculture species in the United Stat...

    Authors: Yu Zhang, Shikai Liu, Jianguo Lu, Yanliang Jiang, Xiaoyu Gao, Parichart Ninwichian, Chao Li, Geoff Waldbieser and Zhanjiang Liu
    Citation: BMC Genomics 2013 14:387
    Content type: Research article Published on:

  23. Obesity-associated organ-specific pathological states can be ensued from the dysregulation of the functions of the adipose tissues, liver and muscle. However, the influence of genetic differences underlying gr...

    Authors: Ayca Dogan, Peter Lasch, Christina Neuschl, Marion K Millrose, Rudi Alberts, Klaus Schughart, Dieter Naumann and Gudrun A Brockmann
    Citation: BMC Genomics 2013 14:386
    Content type: Research article Published on:

  24. Repetitive extragenic palindromic elements (REPs) constitute a group of bacterial genomic repeats known for their high abundance and several roles in host cells´ physiology. We analyzed the phylogenetic distri...

    Authors: Jaroslav Nunvar, Irena Licha and Bohdan Schneider
    Citation: BMC Genomics 2013 14:385
    Content type: Research article Published on:

  25. There is a lack of understanding the evolutionary forces driving niche segregation of closely related organisms. In addition, pinpointing the genes driving ecological divergence is a key goal in molecular ecol...

    Authors: Hanno Schmidt, Bastian Greshake, Barbara Feldmeyer, Thomas Hankeln and Markus Pfenninger
    Citation: BMC Genomics 2013 14:384
    Content type: Research article Published on:

  26. Streptococcus pneumoniae is a leading cause of childhood morbidity and mortality worldwide, despite the availability of effective pneumococcal vaccines. Understanding the molecular interactions between the bacter...

    Authors: Sheila Z Kimaro Mlacha, Sandra Romero-Steiner, Julie C Dunning Hotopp, Nikhil Kumar, Nadeeza Ishmael, David R Riley, Umar Farooq, Todd H Creasy, Luke J Tallon, Xinyue Liu, Cynthia S Goldsmith, Jacquelyn Sampson, George M Carlone, Susan K Hollingshead, J Anthony G Scott and Hervé Tettelin
    Citation: BMC Genomics 2013 14:383
    Content type: Research article Published on:

  27. The domestication and subsequent selection by humans to create breeds and biological types of cattle undoubtedly altered the patterning of variation within their genomes. Strong selection to fix advantageous l...

    Authors: Holly R Ramey, Jared E Decker, Stephanie D McKay, Megan M Rolf, Robert D Schnabel and Jeremy F Taylor
    Citation: BMC Genomics 2013 14:382
    Content type: Research article Published on:

  28. The Fra-1/AP-1 transcription factor regulates the expression of genes controlling various processes including migration, invasion, and survival as well as extracellular remodeling. We recently demonstrated tha...

    Authors: Subbiah Rajasekaran, Narsa M Reddy, Wei Zhang and Sekhar P Reddy
    Citation: BMC Genomics 2013 14:381
    Content type: Research article Published on:

  29. The cumulus cells (CCs) enveloping antral and ovulated oocytes have been regarded as putative source of non-invasive markers of the oocyte developmental competence. A number of studies have indeed observed a c...

    Authors: Giulia Vigone, Valeria Merico, Alessandro Prigione, Francesca Mulas, Lucia Sacchi, Matteo Gabetta, Riccardo Bellazzi, Carlo Alberto Redi, Giuliano Mazzini, James Adjaye, Silvia Garagna and Maurizio Zuccotti
    Citation: BMC Genomics 2013 14:380
    Content type: Research article Published on:

  30. Anecdotal evidence of the involvement of alternative splicing (AS) in the regulation of protein-protein interactions has been reported by several studies. AS events have been shown to significantly occur in re...

    Authors: Alessio Colantoni, Valerio Bianchi, Pier Federico Gherardini, Gianpaolo Scalia Tomba, Gabriele Ausiello, Manuela Helmer-Citterich and Fabrizio Ferrè
    Citation: BMC Genomics 2013 14:379
    Content type: Research article Published on:

  31. Viral upper respiratory tract infections are associated with increased colonization by Streptococcus pneumoniae but the mechanisms underlying this relationship are unclear. The objective of this study is to descr...

    Authors: Sheila Z Kimaro Mlacha, Teresa C T Peret, Nikhil Kumar, Sandra Romero-Steiner, Julie C Dunning Hotopp, Nadeeza Ishmael, Valerie Grinblat-Huse, David R Riley, Dean D Erdman, George M Carlone, Jacquelyn Sampson, J Anthony G Scott and Hervé Tettelin
    Citation: BMC Genomics 2013 14:378
    Content type: Research article Published on:

  32. Streptococcus equi ssp. zooepidemicus (S. zooepidemicus) is an important pathogen causing swine streptococcosis in China. Pathogenicity islands (PAIs) of S. zooepidemicus have been transferred among bacteria thro...

    Authors: Zhe Ma, Jianing Geng, Li Yi, Bin Xu, Ruoyu Jia, Yue Li, Qingshu Meng, Hongjie Fan and Songnian Hu
    Citation: BMC Genomics 2013 14:377
    Content type: Research article Published on:

  33. Differential processing of the amyloid precursor protein liberates either amyloid-ß, a causative agent of Alzheimer’s disease, or secreted amyloid precursor protein-alpha (sAPPα), which promotes neuroprotectio...

    Authors: Margaret M Ryan, Gary P Morris, Bruce G Mockett, Katie Bourne, Wickliffe C Abraham, Warren P Tate and Joanna M Williams
    Citation: BMC Genomics 2013 14:376
    Content type: Research article Published on:

  34. Identifying genes of adaptive significance in a changing environment is a major focus of ecological genomics. Such efforts were restricted, until recently, to researchers studying a small group of model organi...

    Authors: Steve Smith, Louis Bernatchez and Luciano B Beheregaray
    Citation: BMC Genomics 2013 14:375
    Content type: Research article Published on:

  36. Ophiostoma piceae is a wood-staining fungus that grows in the sapwood of conifer logs and lumber. We sequenced its genome and analyzed its transcriptomes under a range of growth conditions. A comparison with the ...

    Authors: Sajeet Haridas, Ye Wang, Lynette Lim, Sepideh Massoumi Alamouti, Shaun Jackman, Rod Docking, Gordon Robertson, Inanc Birol, Jörg Bohlmann and Colette Breuil
    Citation: BMC Genomics 2013 14:373
    Content type: Research article Published on:

  37. Ionizing radiation composed of accelerated ions of high atomic number (Z) and energy (HZE) deposits energy and creates damage in cells in a discrete manner as compared to the random deposition of energy and da...

    Authors: Liang-Hao Ding, Seongmi Park, Michael Peyton, Luc Girard, Yang Xie, John D Minna and Michael D Story
    Citation: BMC Genomics 2013 14:372
    Content type: Research article Published on:

  38. Epidermal Growth Factor (EGF) plays an important function in the regulation of cell growth, proliferation, and differentiation by binding to its receptor (EGFR) and providing cancer cells with increased surviv...

    Authors: Franc Llorens, Manuela Hummel, Lorena Pantano, Xavier Pastor, Ana Vivancos, Ester Castillo, Heidi Mattlin, Anna Ferrer, Matthew Ingham, Marc Noguera, Robert Kofler, Juliane C Dohm, Raquel Pluvinet, Mònica Bayés, Heinz Himmelbauer, José Antonio del Rio…
    Citation: BMC Genomics 2013 14:371
    Content type: Research article Published on:

  39. Genomics and metagenomics are currently leading research areas, with DNA sequences accumulating at an exponential rate. Although enormous advances in DNA sequencing technologies are taking place, progress is f...

    Authors: Agnieszka Zylicz-Stachula, Olga Zolnierkiewicz, Jacek Jasiecki and Piotr M Skowron
    Citation: BMC Genomics 2013 14:370
    Content type: Methodology article Published on:

  41. The genomic architecture of adaptive traits remains poorly understood in non-model plants. Various approaches can be used to bridge this gap, including the mapping of quantitative trait loci (QTL) in pedigrees...

    Authors: Julien Prunier, Betty Pelgas, France Gagnon, Mireille Desponts, Nathalie Isabel, Jean Beaulieu and Jean Bousquet
    Citation: BMC Genomics 2013 14:368
    Content type: Research article Published on:

  42. Mosaic somatic alterations are present in all multi-cellular organisms, but the physiological effects of low-level mosaicism are largely unknown. Most mosaic alterations remain undetectable with current analyt...

    Authors: Joseph D Baugher, Benjamin D Baugher, Matthew D Shirley and Jonathan Pevsner
    Citation: BMC Genomics 2013 14:367
    Content type: Methodology article Published on:

  43. Members of the genus Cronobacter are causes of rare but severe illness in neonates and preterm infants following the ingestion of contaminated infant formula. Seven species have been described and two of the spec...

    Authors: Christopher J Grim, Michael L Kotewicz, Karen A Power, Gopal Gopinath, Augusto A Franco, Karen G Jarvis, Qiong Q Yan, Scott A Jackson, Venugopal Sathyamoorthy, Lan Hu, Franco Pagotto, Carol Iversen, Angelika Lehner, Roger Stephan, Séamus Fanning and Ben D Tall
    Citation: BMC Genomics 2013 14:366
    Content type: Research article Published on:

  44. Despite the frequent isolation of Salmonella enterica sub. enterica serovars Derby and Mbandaka from livestock in the UK and USA little is known about the biological processes maintaining their prevalence. Statis...

    Authors: Matthew R Hayward, Vincent AA Jansen and Martin J Woodward
    Citation: BMC Genomics 2013 14:365
    Content type: Research article Published on:

  45. Actinobacillus pleuropneumoniae is the Gram-negative bacterium responsible for porcine pleuropneumonia. This respiratory infection is highly contagious and characterized by high morbidity and mortality. The objec...

    Authors: Yannick DN Tremblay, Vincent Deslandes and Mario Jacques
    Citation: BMC Genomics 2013 14:364
    Content type: Research article Published on:

  46. The only known albino gorilla, named Snowflake, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous albini...

    Authors: Javier Prado-Martinez, Irene Hernando-Herraez, Belen Lorente-Galdos, Marc Dabad, Oscar Ramirez, Carlos Baeza-Delgado, Carlos Morcillo-Suarez, Can Alkan, Fereydoun Hormozdiari, Emanuele Raineri, Jordi Estellé, Marcos Fernandez-Callejo, Mònica Valles, Lars Ritscher, Torsten Schöneberg, Elisa de la Calle-Mustienes…
    Citation: BMC Genomics 2013 14:363
    Content type: Research article Published on:

  47. Many have assumed that the primary function of sleep is for the brain. We evaluated the molecular consequences of sleep and sleep deprivation outside the brain, in heart and lung. Using microarrays we compared...

    Authors: Ron C Anafi, Renata Pellegrino, Keith R Shockley, Micah Romer, Sergio Tufik and Allan I Pack
    Citation: BMC Genomics 2013 14:362
    Content type: Research article Published on:

  48. Receptor tyrosine kinases (RTK) form a family of transmembrane proteins widely conserved in Metazoa, with key functions in cell-to-cell communication and control of multiple cellular processes. A new family of...

    Authors: Mathieu Vanderstraete, Nadège Gouignard, Arnaud Ahier, Marion Morel, Jérôme Vicogne and Colette Dissous
    Citation: BMC Genomics 2013 14:361
    Content type: Research article Published on:

  49. Hop (Humulus lupulus L.) is cultivated for its cones, the secondary metabolites of which contribute bitterness, flavour and aroma to beer. Molecular breeding methods, such as marker assisted selection (MAS), have...

    Authors: Erin L McAdam, Jules S Freeman, Simon P Whittock, Emily J Buck, Jernej Jakse, Andreja Cerenak, Branka Javornik, Andrzej Kilian, Cai-Hong Wang, Dave Andersen, René E Vaillancourt, Jason Carling, Ron Beatson, Lawrence Graham, Donna Graham, Peter Darby…
    Citation: BMC Genomics 2013 14:360
    Content type: Research article Published on:

  50. Alternative splicing (AS) of genes is an efficient means of generating variation in protein structure and function. AS variation has been observed between tissues, cell types, and different treatments in non-w...

    Authors: Hua Bao, Eryang Li, Shawn D Mansfield, Quentin CB Cronk, Yousry A El-Kassaby and Carl J Douglas
    Citation: BMC Genomics 2013 14:359
    Content type: Research article Published on:

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BMC Genomics

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