Skip to main content

Articles

Page 249 of 338

  3. The complex genome of rapeseed (Brassica napus) is not well understood despite the economic importance of the species. Good knowledge of sequence variation is needed for genetics approaches and breeding purposes....

    Authors: Anja Bus, Jochen Hecht, Bruno Huettel, Richard Reinhardt and Benjamin Stich
    Citation: BMC Genomics 2012 13:281
    Content type: Research article Published on:

  4. Melon (Cucumis melo L.) is a highly diverse species that is cultivated worldwide. Recent advances in massively parallel sequencing have begun to allow the study of nucleotide diversity in this species. The Sanger...

    Authors: José Blanca, Cristina Esteras, Pello Ziarsolo, Daniel Pérez, Victoria Fernández-Pedrosa, Carmen Collado, Raquel Rodríguez de Pablos, Alida Ballester, Cristina Roig, Joaquín Cañizares and Belén Picó
    Citation: BMC Genomics 2012 13:280
    Content type: Research article Published on:

  5. African Green Monkeys (AGM) are amongst the most frequently used nonhuman primate models in clinical and biomedical research, nevertheless only few genomic resources exist for this species. Such information wo...

    Authors: Nicolas Tchitchek, Béatrice Jacquelin, Patrick Wincker, Carole Dossat, Corinne Da Silva, Jean Weissenbach, Antoine Blancher, Michaela Müller-Trutwin and Arndt Benecke
    Citation: BMC Genomics 2012 13:279
    Content type: Research article Published on:

  6. Avian influenza virus (AIV) outbreaks are worldwide threats to both poultry and humans. Our previous study suggested microRNAs (miRNAs) play significant roles in the regulation of host response to AIV infectio...

    Authors: Ying Wang, Vinayak Brahmakshatriya, Blanca Lupiani, Sanjay M Reddy, Benjamin Soibam, Ashley L Benham, Preethi Gunaratne, Hsiao-ching Liu, Nares Trakooljul, Nancy Ing, Ron Okimoto and Huaijun Zhou
    Citation: BMC Genomics 2012 13:278
    Content type: Research article Published on:

  7. Celiac disease (CD) is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins. The CD-toxicity of these proteins and their derived peptides is depending on the p...

    Authors: Elma MJ Salentijn, D Cristina Mitea, Svetlana V Goryunova, Ingrid M van der Meer, Ismael Padioleau, Luud JWJ Gilissen, Frits Koning and Marinus JM Smulders
    Citation: BMC Genomics 2012 13:277
    Content type: Research article Published on:

  8. Lepidoptera encompasses more than 160,000 described species that have been classified into 45–48 superfamilies. The previously determined Lepidoptera mitochondrial genomes (mitogenomes) are limited to six supe...

    Authors: Yong-Qiang Cao, Chuan Ma, Ji-Yue Chen and Da-Rong Yang
    Citation: BMC Genomics 2012 13:276
    Content type: Research article Published on:

  9. Human T cell leukemia virus type 1 (HTLV-1) Tax is a potent activator of viral and cellular gene expression that interacts with a number of cellular proteins. Many reports show that Tax is capable of regulatin...

    Authors: Mariluz Arainga, Hironobu Murakami and Yoko Aida
    Citation: BMC Genomics 2012 13:275
    Content type: Research article Published on:

  10. The criteria for choosing relevant cell lines among a vast panel of available intestinal-derived lines exhibiting a wide range of functional properties are still ill-defined. The objective of this study was, t...

    Authors: Jon Christensen, Sara El-Gebali, Manuela Natoli, Thierry Sengstag, Mauro Delorenzi, Susanne Bentz, Hanifa Bouzourene, Martin Rumbo, Armando Felsani, Sanna Siissalo, Jouni Hirvonen, Maya R Vila, Piercarlo Saletti, Michel Aguet and Pascale Anderle
    Citation: BMC Genomics 2012 13:274
    Content type: Research article Published on:

  11. Copy Number Variations (CNVs) have been shown important in both normal phenotypic variability and disease susceptibility, and are increasingly accepted as another important source of genetic variation compleme...

    Authors: Jiying Wang, Jicai Jiang, Weixuan Fu, Li Jiang, Xiangdong Ding, Jian-Feng Liu and Qin Zhang
    Citation: BMC Genomics 2012 13:273
    Content type: Research article Published on:

  12. Transposable elements (TEs), both DNA transposons and retrotransposons, are genetic elements with the main characteristic of being able to mobilize and amplify their own representation within genomes, utilizin...

    Authors: Rita D Fernández-Medina, José M C Ribeiro, Claudia M A Carareto, Luciane Velasque and Cláudio J Struchiner
    Citation: BMC Genomics 2012 13:272
    Content type: Research article Published on:

  13. Coral reefs are hotspots of oceanic biodiversity, forming the foundation of ecosystems that are important both ecologically and for their direct practical impacts on humans. Corals are declining globally due t...

    Authors: Erik M Lehnert, Matthew S Burriesci and John R Pringle
    Citation: BMC Genomics 2012 13:271
    Content type: Research article Published on:

  14. A complete assembled genome sequence of wheat is not yet available. Therefore, model plant systems for wheat are very valuable. Brachypodium distachyon (Brachypodium) is such a system. The WRKY family of transcri...

    Authors: Prateek Tripathi, Roel C Rabara, Tanner J Langum, Ashley K Boken, Deena L Rushton, Darius D Boomsma, Charles I Rinerson, Jennifer Rabara, R Neil Reese, Xianfeng Chen, Jai S Rohila and Paul J Rushton
    Citation: BMC Genomics 2012 13:270
    Content type: Research article Published on:

  15. Phakopsora pachyrhizi is an obligate fungal pathogen causing Asian soybean rust (ASR). A dual approach was taken to examine the molecular and biochemical processes occurring during the development of appressoria,...

    Authors: Christine L Stone, Michael B McMahon, Laurie L Fortis, Alberto Nuñez, Gary W Smythers, Douglas G Luster and Reid D Frederick
    Citation: BMC Genomics 2012 13:269
    Content type: Research article Published on:

  16. Prior to this study, relatively few strains of Francisella had been genome-sequenced. Previously published Francisella genome sequences were largely restricted to the zoonotic agent F. tularensis. Only limited da...

    Authors: Andreas Sjödin, Kerstin Svensson, Caroline Öhrman, Jon Ahlinder, Petter Lindgren, Samuel Duodu, Anders Johansson, Duncan J Colquhoun, Pär Larsson and Mats Forsman
    Citation: BMC Genomics 2012 13:268
    Content type: Research article Published on:

  17. Chitosan oligosaccharide (COS), a deacetylated derivative of chitin, is an abundant, and renewable natural polymer. COS has higher antimicrobial properties than chitosan and is presumed to act by disrupting/pe...

    Authors: Maria DLA Jaime, Luis Vicente Lopez-Llorca, Ana Conesa, Anna Y Lee, Michael Proctor, Lawrence E Heisler, Marinella Gebbia, Guri Giaever, J Timothy Westwood and Corey Nislow
    Citation: BMC Genomics 2012 13:267
    Content type: Research article Published on:

  18. De novo assembly of transcript sequences produced by next-generation sequencing technologies offers a rapid approach to obtain expressed gene sequences for non-model organisms. Ammopiptanthus mongolicus, a super-...

    Authors: Yijun Zhou, Fei Gao, Ran Liu, Jinchao Feng and Hongjie Li
    Citation: BMC Genomics 2012 13:266
    Content type: Research article Published on:

  19. Epulopiscium sp. type B, a large intestinal bacterial symbiont of the surgeonfish Naso tonganus, does not reproduce by binary fission. Instead, it forms multiple intracellular offspring using a process with morph...

    Authors: David A Miller, Garret Suen, Kendall D Clements and Esther R Angert
    Citation: BMC Genomics 2012 13:265
    Content type: Research article Published on:

  20. MicroRNAs (miRNAs) modulate gene expression in different tissues and at diverse developmental stages, including grain development in japonica rice. To identify novel miRNAs in indica rice and to study their ex...

    Authors: Ying Lan, Ning Su, Yi Shen, Rongzhi Zhang, Fuqing Wu, Zhijun Cheng, Jiulin Wang, Xin Zhang, Xiupin Guo, Cailin Lei, Jie Wang, Ling Jiang, Long Mao and Jianmin Wan
    Citation: BMC Genomics 2012 13:264
    Content type: Research article Published on:

  22. Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations, little is known about the biology of this important hu...

    Authors: A Taylor Bright, Ryan Tewhey, Shira Abeles, Raul Chuquiyauri, Alejandro Llanos-Cuentas, Marcelo U Ferreira, Nicholas J Schork, Joseph M Vinetz and Elizabeth A Winzeler
    Citation: BMC Genomics 2012 13:262
    Content type: Methodology article Published on:

  23. Bats are the natural reservoir host for a range of emerging and re-emerging viruses, including SARS-like coronaviruses, Ebola viruses, henipaviruses and Rabies viruses. However, the mechanisms responsible for ...

    Authors: Anthony T Papenfuss, Michelle L Baker, Zhi-Ping Feng, Mary Tachedjian, Gary Crameri, Chris Cowled, Justin Ng, Vijaya Janardhana, Hume E Field and Lin-Fa Wang
    Citation: BMC Genomics 2012 13:261
    Content type: Research article Published on:

  24. Evolution of novel protein-coding genes is the bedrock of adaptive evolution. Recently, we identified six protein-coding genes with similar signal sequence from Schistosoma japonicum egg stage mRNA using signal s...

    Authors: Evaristus Chibunna Mbanefo, Yu Chuanxin, Mihoko Kikuchi, Mohammed Nasir Shuaibu, Daniel Boamah, Masashi Kirinoki, Naoko Hayashi, Yuichi Chigusa, Yoshio Osada, Shinjiro Hamano and Kenji Hirayama
    Citation: BMC Genomics 2012 13:260
    Content type: Research article Published on:

  25. Next-generation sequencing methods have contributed to rapid progress in the fields of genomics and population genetics. Using this high-throughput and cost-effective technology, a number of studies have estim...

    Authors: Soo Hyung Eo and J Andrew DeWoody
    Citation: BMC Genomics 2012 13:259
    Content type: Research article Published on:

  26. Mycobacterium ulcerans is an unusual bacterial pathogen with elusive origins. While closely related to the aquatic dwelling M. marinum, M. ulcerans has evolved the ability to produce the immunosuppressive polyket...

    Authors: Kenneth D Doig, Kathryn E Holt, Janet AM Fyfe, Caroline J Lavender, Miriam Eddyani, Françoise Portaels, Dorothy Yeboah-Manu, Gerd Pluschke, Torsten Seemann and Timothy P Stinear
    Citation: BMC Genomics 2012 13:258
    Content type: Research article Published on:

  27. Scaleless (sc/sc) chickens carry a single recessive mutation that causes a lack of almost all body feathers, as well as foot scales and spurs, due to a failure of skin patterning during embryogenesis. This sponta...

    Authors: Kirsty L Wells, Yair Hadad, Danny Ben-Avraham, Jossi Hillel, Avigdor Cahaner and Denis J Headon
    Citation: BMC Genomics 2012 13:257
    Content type: Research article Published on:

  28. Escherichia coli is an important species of bacteria that can live as a harmless inhabitant of the guts of many animals, as a pathogen causing life-threatening conditions or freely in the non-host environment. Th...

    Authors: Xavier Didelot, Guillaume Méric, Daniel Falush and Aaron E Darling
    Citation: BMC Genomics 2012 13:256
    Content type: Research article Published on:

  29. Telomeres are nucleoprotein complexes at the end of linear eukaryotic chromosomes which maintain the genome integrity by regulating telomere length, preventing recombination and end to end fusion events. Multi...

    Authors: Easwaran Sreesankar, Ramamoorthy Senthilkumar, Vellaichamy Bharathi, Rakesh K Mishra and Krishnaveni Mishra
    Citation: BMC Genomics 2012 13:255
    Content type: Research article Published on:

  30. An organism can respond to changing environmental conditions by adjusting gene regulation and by forming alternative phenotypes. In nematodes, these mechanisms are coupled because many species will form dauer ...

    Authors: Amit Sinha, Ralf J Sommer and Christoph Dieterich
    Citation: BMC Genomics 2012 13:254
    Content type: Research article Published on:

  31. CCCH zinc finger proteins contain a typical motif of three cysteines and one histidine residues and serve regulatory functions at all stages of mRNA metabolism. In plants, CCCH type zinc finger proteins compri...

    Authors: Guohua Chai, Ruibo Hu, Dongyuan Zhang, Guang Qi, Ran Zuo, Yingping Cao, Peng Chen, Yingzhen Kong and Gongke Zhou
    Citation: BMC Genomics 2012 13:253
    Content type: Research article Published on:

  32. The complex balance between environmental and host factors is an important determinant of susceptibility to infection. Disturbances of this equilibrium may result in multifactorial diseases as illustrated by t...

    Authors: Rafael Diego Rosa, Julien de Lorgeril, Patrick Tailliez, Roman Bruno, David Piquemal and Evelyne Bachère
    Citation: BMC Genomics 2012 13:252
    Content type: Research article Published on:

  33. The HOX gene clusters are thought to be highly conserved amongst mammals and other vertebrates, but the long non-coding RNAs have only been studied in detail in human and mouse. The sequencing of the kangaroo ...

    Authors: Hongshi Yu, James Lindsay, Zhi-Ping Feng, Stephen Frankenberg, Yanqiu Hu, Dawn Carone, Geoff Shaw, Andrew J Pask, Rachel O’Neill, Anthony T Papenfuss and Marilyn B Renfree
    Citation: BMC Genomics 2012 13:251
    Content type: Research article Published on:

  34. Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessati...

    Authors: Aran O’Loughlin, David J Lynn, Mark McGee, Sean Doyle, Matthew McCabe and Bernadette Earley
    Citation: BMC Genomics 2012 13:250
    Content type: Research article Published on:

  35. Non-synonymous single nucleotide polymorphisms (nsSNPs) alter the protein sequence and can cause disease. The impact has been described by reliable experiments for relatively few mutations. Here, we study pred...

    Authors: Christian Schaefer, Yana Bromberg, Dominik Achten and Burkhard Rost
    Citation: BMC Genomics 2012 13(Suppl 4):S11
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  36. Mutations as sources of evolution have long been the focus of attention in the biomedical literature. Accessing the mutational information and their impacts on protein properties facilitates research in variou...

    Authors: Nona Naderi and René Witte
    Citation: BMC Genomics 2012 13(Suppl 4):S10
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  37. Large-scale tumor sequencing projects are now underway to identify genetic mutations that drive tumor initiation and development. Most studies take a gene-based approach to identifying driver mutations, highli...

    Authors: Nathan L Nehrt, Thomas A Peterson, DoHwan Park and Maricel G Kann
    Citation: BMC Genomics 2012 13(Suppl 4):S9
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  38. Various computational methods are presently available to classify whether a protein variation is disease-associated or not. However data derived from recent technological advancements make it feasible to exten...

    Authors: Pier Luigi Martelli, Piero Fariselli, Eva Balzani and Rita Casadio
    Citation: BMC Genomics 2012 13(Suppl 4):S8
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  40. The structure of RiboNucleic Acid (RNA) has the potential to be altered by a Single Nucleotide Polymorphism (SNP). Disease-associated SNPs mapping to non-coding regions of the genome that are transcribed into ...

    Authors: Justin Ritz, Joshua S Martin and Alain Laederach
    Citation: BMC Genomics 2012 13(Suppl 4):S6
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  41. Non-synonymous coding SNPs (nsSNPs) that are associated to disease can also be related with alterations in protein stability. Computational methods are available to predict the effect of single amino acid subs...

    Authors: Ezequiel Juritz, Maria Silvina Fornasari, Pier Luigi Martelli, Piero Fariselli, Rita Casadio and Gustavo Parisi
    Citation: BMC Genomics 2012 13(Suppl 4):S5
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  42. Amino acid point mutations (nsSNPs) may change protein structure and function. However, no method directly predicts the impact of mutations on structure. Here, we compare pairs of pentamers (five consecutive r...

    Authors: Christian Schaefer and Burkhard Rost
    Citation: BMC Genomics 2012 13(Suppl 4):S4
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  43. Most of the many mutations described in human protein kinases are tolerated without significant disruption of the corresponding structures or molecular functions, while some of them have been associated to a v...

    Authors: Jose MG Izarzugaza, Angela del Pozo, Miguel Vazquez and Alfonso Valencia
    Citation: BMC Genomics 2012 13(Suppl 4):S3
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  44. Prediction methods are increasingly used in biosciences to forecast diverse features and characteristics. Binary two-state classifiers are the most common applications. They are usually based on machine learni...

    Authors: Mauno Vihinen
    Citation: BMC Genomics 2012 13(Suppl 4):S2
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 4

  46. The insertion element IS6110 is one of the main sources of genomic variability in Mycobacterium tuberculosis, the etiological agent of human tuberculosis. Although IS 6110 has been used extensively as an epidemio...

    Authors: Alejandro Reyes, Andrea Sandoval, Andrés Cubillos-Ruiz, Katherine E Varley, Ivan Hernández-Neuta, Sofía Samper, Carlos Martín, María Jesús García, Viviana Ritacco, Lucelly López, Jaime Robledo, María Mercedes Zambrano, Robi D Mitra and Patricia Del Portillo
    Citation: BMC Genomics 2012 13:249
    Content type: Research article Published on:

  47. Polyploidy often results in considerable changes in gene expression, both immediately and over evolutionary time. New phenotypes often arise with polyploid formation and may contribute to the fitness of polypl...

    Authors: Janet Higgins, Andreas Magusin, Martin Trick, Fiona Fraser and Ian Bancroft
    Citation: BMC Genomics 2012 13:247
    Content type: Research article Published on:

  49. Carotenoids are a heterogeneous group of plant isoprenoids primarily involved in photosynthesis. In plants the cleavage of carotenoids leads to the formation of the phytohormones abscisic acid and strigolacton...

    Authors: Philip R Young, Justin G Lashbrooke, Erik Alexandersson, Dan Jacobson, Claudio Moser, Riccardo Velasco and Melané A Vivier
    Citation: BMC Genomics 2012 13:243
    Content type: Research article Published on:

  50. Genotypes obtained with commercial SNP arrays have been extensively used in many large case-control or population-based cohorts for SNP-based genome-wide association studies for a multitude of traits. Yet, the...

    Authors: Armand Valsesia, Brian J Stevenson, Dawn Waterworth, Vincent Mooser, Peter Vollenweider, Gérard Waeber, C Victor Jongeneel, Jacques S Beckmann, Zoltán Kutalik and Sven Bergmann
    Citation: BMC Genomics 2012 13:241
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 3.5
    5-year Journal Impact Factor: 4.1
    Source Normalized Impact per Paper (SNIP): 1.083
    SCImago Journal Rank (SJR): 1.047

    Speed 2023
    Submission to first editorial decision (median days): 21
    Submission to acceptance (median days): 137

    Usage 2023
    Downloads: 7,167,242
    Altmetric mentions: 4,454

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us