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6356 result(s) for 'general transcription factors vs specific' within BMC Genomics

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  1. The transcriptional corepressor Groucho (Gro) is required for the function of many developmentally regulated DNA binding repressors, thus helping to define the gene expression profile of each cell during devel...

    Authors: Michael Chambers, Wiam Turki-Judeh, Min Woo Kim, Kenny Chen, Sean D. Gallaher and Albert J. Courey
    Citation: BMC Genomics 2017 18:215
    Content type: Research article Published on:

  2. Insecticide resistance (IR) is one of the major threats to malaria vector control programs in endemic countries. However, the mechanisms underlying IR are poorly understood. Thus, investigating gene expression...

    Authors: Helga Saizonou, Lucy Mackenzie Impoinvil, Dieunel Derilus, Diana Omoke, Stephen Okeyo, Nsa Dada, Claudia Corredor, Nicola Mulder, Audrey Lenhart, Eric Ochomo and Luc S. Djogbénou
    Citation: BMC Genomics 2024 25:348
    Content type: Research Published on:

  3. Mosquitoes are prolific vectors of human pathogens, therefore a clear and accurate understanding of the organization of their antimicrobial defenses is crucial for informing the development of transmission con...

    Authors: Bretta Hixson, Louise Huot, Bianca Morejon, Xiaowei Yang, Peter Nagy, Kristin Michel and Nicolas Buchon
    Citation: BMC Genomics 2024 25:353
    Content type: Research Published on:

  4. Black pearl farming is based on culture of the blacklip pearl oyster Pinctada margaritifera (Mollusca, lophotrochozoa), a protandrous hermaphrodite species. At first maturation, all individuals are males. The fem...

    Authors: Vaihiti Teaniniuraitemoana, Arnaud Huvet, Peva Levy, Christophe Klopp, Emeline Lhuillier, Nabila Gaertner-Mazouni, Yannick Gueguen and Gilles Le Moullac
    Citation: BMC Genomics 2014 15:491
    Content type: Research article Published on:

  5. A substantial fraction of non-coding DNA sequences of multicellular eukaryotes is under selective constraint. In particular, ~5% of the human genome consists of conserved non-coding sequences (CNSs). CNSs diff...

    Authors: Simon Minovitsky, Philip Stegmaier, Alexander Kel, Alexey S Kondrashov and Inna Dubchak
    Citation: BMC Genomics 2007 8:378
    Content type: Research article Published on:

  6. Circannual rhythms in vertebrates can influence a wide variety of physiological processes. Some notable examples include annual reproductive cycles and for poikilotherms, seasonal changes modulating growth. In...

    Authors: Roy G. Danzmann, Andrea L. Kocmarek, Joseph D. Norman, Caird E. Rexroad III and Yniv Palti
    Citation: BMC Genomics 2016 17:60
    Content type: Research article Published on:

  7. At present, nothing is known of the role of miRNAs in the immune response in vivo despite the fact that inflammation is thought to underlie multiple acute and chronic diseases. In these circumstances, patients ar...

    Authors: Sterghios A Moschos, Andrew E Williams, Mark M Perry, Mark A Birrell, Maria G Belvisi and Mark A Lindsay
    Citation: BMC Genomics 2007 8:240
    Content type: Research article Published on:

  8. In the recent years, there has been a rise in gene expression profiling reports. Unfortunately, it has not been possible to make maximum use of available gene expression data. Many databases and programs can b...

    Authors: Kshitish K Acharya, Darshan S Chandrashekar, Neelima Chitturi, Hardik Shah, Varun Malhotra, Sreelakshmi KS, Deepti H, Akhilesh Bajpai, Sravanthi Davuluri, Pranami Bora and Leena Rao
    Citation: BMC Genomics 2010 11:467
    Content type: Methodology article Published on:

  9. Expression of the LIM-homeobox gene Lhx2 in murine hematopoietic cells allows for the generation of hematopoietic stem cell (HSC)-like cell lines. To address the molecular basis of Lhx2 function, we generated HSC...

    Authors: Karin Richter, Valtteri Wirta, Lina Dahl, Sara Bruce, Joakim Lundeberg, Leif Carlsson and Cecilia Williams
    Citation: BMC Genomics 2006 7:75
    Content type: Research article Published on:

  11. Gibberellins (GAs) can have profound effects on growth and development in higher plants. In contrast to their flowering-promotive role in many well-studied plants, GAs can repress flowering in woody perennial ...

    Authors: Songwen Zhang, Christopher Gottschalk and Steve van Nocker
    Citation: BMC Genomics 2019 20:747
    Content type: Research article Published on:

  12. Clostridium perfringens causes toxin-mediated diseases, including gas gangrene (clostridial myonecrosis) and food poisoning in humans. The production of the toxins implicated in gas ga...

    Authors: Lee-Yean Low, Paul F. Harrison, Ya-Hsun Lin, John D. Boyce, Julian I. Rood and Jackie K. Cheung
    Citation: BMC Genomics 2016 17:391
    Content type: Research article Published on:

  13. Many genes oscillate in their level of expression through the cell division cycle. Previous studies have identified such genes by applying Fourier analysis to cell cycle time course experiments. Typically, suc...

    Authors: Saumyadipta Pyne, Roee Gutman, Chang Sik Kim and Bruce Futcher
    Citation: BMC Genomics 2009 10:440
    Content type: Research article Published on:

  14. Plants can defend themselves against herbivorous insects prior to the onset of larval feeding by responding to the eggs laid on their leaves. In the European field elm (Ulmus minor), egg laying by the elm leaf be...

    Authors: Kerstin Büchel, Eric McDowell, Will Nelson, Anne Descour, Jonathan Gershenzon, Monika Hilker, Carol Soderlund, David R Gang, Trevor Fenning and Torsten Meiners
    Citation: BMC Genomics 2012 13:242
    Content type: Research article Published on:

  15. Autotoxicity plays an important role in regulating crop yield and quality. To help characterize the autotoxicity mechanism of rice, we performed a large-scale, transcriptomic analysis of the rice root response...

    Authors: Wen-Chang Chi, Yun-An Chen, Yu-Chywan Hsiung, Shih-Feng Fu, Chang-Hung Chou, Ngoc Nam Trinh, Ying-Chih Chen and Hao-Jen Huang
    Citation: BMC Genomics 2013 14:351
    Content type: Research article Published on:

  16. Gene duplication is a normal evolutionary process. If there is no selective advantage in keeping the duplicated gene, it is usually reduced to a pseudogene and disappears from the genome. However, some paralog...

    Authors: Marit S Bratlie, Jostein Johansen, Brad T Sherman, Da Wei Huang, Richard A Lempicki and Finn Drabløs
    Citation: BMC Genomics 2010 11:588
    Content type: Research article Published on:

  17. Flowering time, plant height and seed yield are strongly influenced by climatic and day-length adaptation in crop plants. To investigate these traits under highly diverse field conditions in the important oils...

    Authors: Sarah Schiessl, Federico Iniguez-Luy, Wei Qian and Rod J. Snowdon
    Citation: BMC Genomics 2015 16:737
    Content type: Research article Published on:

  18. Exosomes are nanoscale membrane vesicles released by most cells. They are postulated to be involved in cell–cell communication and genetic reprogramming of their target cells. In addition to proteins and lipid...

    Authors: Arsen O Batagov, Vladimir A Kuznetsov and Igor V Kurochkin
    Citation: BMC Genomics 2011 12(Suppl 3):S18
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 12 Supplement 3

  19. Nitrogen is an essential element for bacterial growth and an important component of biological macromolecules. Consequently, responding to nitrogen limitation is critical for bacterial survival and involves th...

    Authors: Victoria A Jenkins, Geraint R Barton, Brian D Robertson and Kerstin J Williams
    Citation: BMC Genomics 2013 14:301
    Content type: Research article Published on:

  20. Plants are attacked by diverse insect and mammalian herbivores and respond with different physical and chemical defences. Transcriptional changes underlie these phenotypic changes. Simulated herbivory has been...

    Authors: J. S. Nantongo, B. M. Potts, T. Frickey, E. Telfer, H. Dungey, H. Fitzgerald and J. M. O’Reilly-Wapstra
    Citation: BMC Genomics 2022 23:52
    Content type: Research Published on:

  21. Benzo[a]pyrene (BaP) is a widespread environmental genotoxic carcinogen that damages DNA by forming adducts. This damage along with activation of the aryl hydrocarbon receptor (AHR) induces complex transcripti...

    Authors: Hamza Hamouchene, Volker M Arlt, Ian Giddings and David H Phillips
    Citation: BMC Genomics 2011 12:333
    Content type: Research article Published on:

  22. Alginate is an important cell wall component and mannitol is a soluble storage carbon substance in the brown seaweed Saccharina japonica. Their contents vary with kelp developmental periods and harvesting time. A...

    Authors: Zhanru Shao, Pengyan Zhang, Chang Lu, Shaoxuan Li, Zhihang Chen, Xiuliang Wang and Delin Duan
    Citation: BMC Genomics 2019 20:975
    Content type: Research article Published on:

  23. Suicide is an important and potentially preventable consequence of serious mental disorders of unknown etiology. Gene expression profiling technology provides an unbiased approach to identifying candidate gene...

    Authors: Sanghyeon Kim, Kwang-Ho Choi, Ali Fuat Baykiz and Howard K Gershenfeld
    Citation: BMC Genomics 2007 8:413
    Content type: Research article Published on:

  24. Common bean (Phaseolus vulgaris) is grown throughout the world and comprises roughly 50% of the grain legumes consumed worldwide. Despite this, genetic resources for common beans have been lacking. Next generatio...

    Authors: Jamie A O’Rourke, Luis P Iniguez, Fengli Fu, Bruna Bucciarelli, Susan S Miller, Scott A Jackson, Philip E McClean, Jun Li, Xinbin Dai, Patrick X Zhao, Georgina Hernandez and Carroll P Vance
    Citation: BMC Genomics 2014 15:866
    Content type: Research article Published on:

  25. Promoters are key players in gene regulation. They receive signals from various sources (e.g. cell surface receptors) and control the level of transcription initiation, which largely determines gene expression...

    Authors: Christoph Dieterich, Steffen Grossmann, Andrea Tanzer, Stefan Röpcke, Peter F Arndt, Peter F Stadler and Martin Vingron
    Citation: BMC Genomics 2005 6:24
    Content type: Database Published on:

  26. Low temperatures decrease the capacity for biomass production and lead to growth retardation up to irreversible cellular damage in modern maize cultivars. European flint landraces are an untapped genetic resou...

    Authors: Felix P. Frey, Marion Pitz, Chris-Carolin Schön and Frank Hochholdinger
    Citation: BMC Genomics 2020 21:300
    Content type: Research article Published on:

  27. In the context of early sowing of maize as a promising adaptation strategy that could significantly reduce the negative effects of climate change, an in-depth understanding of mechanisms underlying plant respo...

    Authors: Manja Božić, Dragana Ignjatović Micić, Nenad Delić and Ana Nikolić
    Citation: BMC Genomics 2024 25:479
    Content type: Research Published on:

  28. The origin of novel traits and their subsequent diversification represent central themes in evo-devo and evolutionary ecology. Here we explore the genetic and genomic basis of a class of traits that is both no...

    Authors: Teiya Kijimoto, James Costello, Zuojian Tang, Armin P Moczek and Justen Andrews
    Citation: BMC Genomics 2009 10:504
    Content type: Research article Published on:

  29. Soybean is a major crop that provides an important source of protein and oil to humans and animals, but its production can be dramatically decreased by the occurrence of drought stress. Soybeans can survive dr...

    Authors: Li Song, Silvas Prince, Babu Valliyodan, Trupti Joshi, Joao V. Maldonado dos Santos, Jiaojiao Wang, Li Lin, Jinrong Wan, Yongqin Wang, Dong Xu and Henry T. Nguyen
    Citation: BMC Genomics 2016 17:57
    Content type: Research article Published on:

  30. As one of the microelements, nitrogen play essential roles in cereal production. Although the use of chemical fertilizers has significantly improved the yield of wheat, it has also caused increasingly adverse ...

    Authors: Hanxia Wang, Qiaoyun Ma, Fuhua Shan, Liping Tian, Jie Gong, Wei Quan, Weibing Yang, Qiling Hou, Fengting Zhang and Shengquan Zhang
    Citation: BMC Genomics 2022 23:727
    Content type: Research Published on:

  31. Root length and its architecture govern the adaptability of plants to various stress conditions, including drought stress. Genetic variations in root growth, length, and architecture are genotypes dependent. I...

    Authors: Alok Ranjan, Neha Pandey, Deepika Lakhwani, Neeraj Kumar Dubey, Uday V Pathre and Samir V Sawant
    Citation: BMC Genomics 2012 13:680
    Content type: Research article Published on:

  32. Manipulating maternal nutrition during specific periods of gestation can result in re-programming of fetal and post-natal development. In this experiment we investigated how a feed restriction of 85% compared ...

    Authors: Francois Paradis, Katie M. Wood, Kendall C. Swanson, Stephen P. Miller, Brian W. McBride and Carolyn Fitzsimmons
    Citation: BMC Genomics 2017 18:632
    Content type: Research article Published on:

  33. Some of the biochemical events that lead to necrosis of the liver are well-known. However, the pathogenesis of necrosis of the liver from exposure to hepatotoxicants is a complex biological response to the inj...

    Authors: Lingkang Huang, Alexandra N Heinloth, Zhao-Bang Zeng, Richard S Paules and Pierre R Bushel
    Citation: BMC Genomics 2008 9:288
    Content type: Research article Published on:

  34. Genomic imprinting is an epigenetically regulated process wherein genes are expressed in a parent-of-origin specific manner. Many imprinted genes were initially identified in mice; some of these were subsequen...

    Authors: Radhika Das, Yew Kok Lee, Ruslan Strogantsev, Shengnan Jin, Yen Ching Lim, Poh Yong Ng, Xueqin Michelle Lin, Keefe Chng, George SH Yeo, Anne C Ferguson-Smith and Chunming Ding
    Citation: BMC Genomics 2013 14:685
    Content type: Research article Published on:

  35. C57BL/6J mice possess a single intelectin (Itln) gene on chromosome 1. The function of intelectins is not well understood, but roles have been postulated in insulin sensitivity, bacterial recognition, intestinal ...

    Authors: Zen H Lu, Alex di Domenico, Steven H Wright, Pamela A Knight, C Bruce A Whitelaw and Alan D Pemberton
    Citation: BMC Genomics 2011 12:110
    Content type: Research article Published on:

  36. Cellular function is regulated by the balance of stringently regulated amounts of mRNA. Previous reports revealed that RNA polymerase II (RNAPII), which transcribes mRNA, can be classified into the pausing sta...

    Authors: Jun Odawara, Akihito Harada, Tomohiko Yoshimi, Kazumitsu Maehara, Taro Tachibana, Seiji Okada, Koichi Akashi and Yasuyuki Ohkawa
    Citation: BMC Genomics 2011 12:516
    Content type: Research article Published on:

  37. The goal of most programs developed to find transcription factor binding sites (TFBSs) is the identification of discrete sequence motifs that are significantly over-represented in a given set of sequences wher...

    Authors: Patricia Oliver, Martín Peralta-Gil, María-Luisa Tabche and Enrique Merino
    Citation: BMC Genomics 2016 17:686
    Content type: Methodology article Published on:

  38. Mesorhizobium metallidurans STM 2683T and Mesorhizobium sp. strain STM 4661 were isolated from nodules of the metallicolous legume Anthyllis vulneraria from distant mining spoils. They tolerate unusually high Zin...

    Authors: Géraldine Maynaud, Brigitte Brunel, Damien Mornico, Maxime Durot, Dany Severac, Emeric Dubois, Elisabeth Navarro, Jean-Claude Cleyet-Marel and Antoine Le Quéré
    Citation: BMC Genomics 2013 14:292
    Content type: Research article Published on:

  39. The apicomplexan parasite Toxoplasma gondii is cosmopolitan in nature, largely as a result of its highly flexible life cycle. Felids are its only definitive hosts and a wide range of mammals and birds serve as in...

    Authors: Adrian B Hehl, Walter U Basso, Christoph Lippuner, Chandra Ramakrishnan, Michal Okoniewski, Robert A Walker, Michael E Grigg, Nicholas C Smith and Peter Deplazes
    Citation: BMC Genomics 2015 16:66
    Content type: Research article Published on:

  40. Verticillium wilt, caused by the fungal pathogen Verticillium dahliae, is the most severe disease in cotton (Gossypium spp.), causing great lint losses worldwide. Disease management could be achieved in the field...

    Authors: Yan Zhang, Xing Fen Wang, Ze Guo Ding, Qing Ma, Gui Rong Zhang, Shu Ling Zhang, Zhi Kun Li, Li Qiang Wu, Gui Yin Zhang and Zhi Ying Ma
    Citation: BMC Genomics 2013 14:637
    Content type: Research article Published on:

  41. Lichens are symbiotic organisms with a fungal and an algal or a cyanobacterial partner. Lichens inhabit some of the harshest climates on earth and most lichen species are desiccation-tolerant. Lichen desiccati...

    Authors: Sini Junttila, Asta Laiho, Attila Gyenesei and Stephen Rudd
    Citation: BMC Genomics 2013 14:870
    Content type: Research article Published on:

  42. Pekin duck is an important animal model for its ability for fat synthesis and deposition. However, transcriptional dynamic regulation of adipose differentiation driven by complex signal cascades remains largel...

    Authors: Zheng Wang, Zhong-Tao Yin, Fan Zhang, Xiao-Qin Li, Si-Rui Chen, Ning Yang, Tom E. Porter and Zhuocheng Hou
    Citation: BMC Genomics 2019 20:688
    Content type: Research article Published on:

  43. Clostridium beijerinckii is an important solvent producing microorganism. The genome of C. beijerinckii NCIMB 8052 has recently been sequenced. Although transcriptome structure is important in order to reveal the...

    Authors: Yi Wang, Xiangzhen Li, Yuejian Mao and Hans P Blaschek
    Citation: BMC Genomics 2011 12:479
    Content type: Research article Published on:

  44. Most insects are relatively short-lived, with a maximum lifespan of a few weeks, like the aging model organism, the fruit-fly Drosophila melanogaster. By contrast, the queens of many social insects (termites, ant...

    Authors: José Manuel Monroy Kuhn, Karen Meusemann and Judith Korb
    Citation: BMC Genomics 2021 22:339
    Content type: Research Published on:

  45. The fungal genus Stachybotrys produces several diverse toxins that affect human health. Its strains comprise two mutually-exclusive toxin chemotypes, one producing satratoxins, which are a subclass of trichothece...

    Authors: Jeremy Semeiks, Dominika Borek, Zbyszek Otwinowski and Nick V Grishin
    Citation: BMC Genomics 2014 15:590
    Content type: Research article Published on:

  46. We introduce mirTarRnaSeq, an R/Bioconductor package for quantitative assessment of miRNA-mRNA relationships within sample cohorts. mirTarRnaSeq is a statistical package to explore predicted or pre-hypothesized m...

    Authors: Mercedeh Movassagh, Sarah U. Morton, Christine Hehnly, Jasmine Smith, Trang T. Doan, Rafael Irizarry, James R. Broach, Steven J. Schiff, Jeffrey A. Bailey and Joseph N. Paulson
    Citation: BMC Genomics 2022 23:439
    Content type: Research article Published on:

  47. Peripheral arterial disease (PAD), a major manifestation of atherosclerosis, is associated with significant cardiovascular morbidity, limb loss and death. However, mechanisms underlying the genesis and progres...

    Authors: Shijun Fu, Haiguang Zhao, Jiantao Shi, Arhat Abzhanov, Keith Crawford, Lucila Ohno-Machado, Jianqin Zhou, Yanzhi Du, Winston Patrick Kuo, Ji Zhang, Mier Jiang and Jason Gang Jin
    Citation: BMC Genomics 2008 9:369
    Content type: Research article Published on:

  48. Saponins are mainly amphipathic glycosides that posses many biological activities and confer potential health benefits to humans. Inspite of its medicinal attributes most of the triterpenes and enzymes involve...

    Authors: Swati Upadhyay, Ujjal J Phukan, Sonal Mishra and Rakesh Kumar Shukla
    Citation: BMC Genomics 2014 15:746
    Content type: Research article Published on:

  49. The Myxococcales are well known for their predatory and developmental social processes, and for the molecular complexity of regulation of these processes. Many species within this order have unusually large ge...

    Authors: Anna L. McLoon, Max E. Boeck, Marc Bruckskotten, Alexander C. Keyel and Lotte Søgaard-Andersen
    Citation: BMC Genomics 2021 22:784
    Content type: Research Published on:

  50. The medicinal plant, Catharanthus roseus (C. roseus), accumulates a wide range of terpenoid indole alkaloids (TIAs). Ethylene (ET) and methyl-jasmonate (MeJA) were previously reported as effective elicitors for t...

    Authors: Ya-jie Pan, Ying-chao Lin, Bo-fan Yu, Yuan-gang Zu, Fang Yu and Zhong-Hua Tang
    Citation: BMC Genomics 2018 19:508
    Content type: Research article Published on:

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BMC Genomics

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