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  1. Drug-resistant bacteria are important carriers of antibiotic-resistant genes (ARGs). This fact is crucial for the development of precise clinical drug treatment strategies. Long-read sequencing platforms such ...

    Authors: Jidong Lang, Yanju Li, Wenjuan Yang, Ruyi Dong, Yuebin Liang, Jia Liu, Lanyou Chen, Weiwei Wang, Binbin Ji, Geng Tian, Nanying Che and Bo Meng
    Citation: BMC Genomics 2022 23(Suppl 1):316

    This article is part of a Supplement: Volume 23 Supplement 1

  2. Authors: Jigme Dorji, Christy J. Vander Jagt, Josie B. Garner, Leah C. Marett, Brett A. Mason, Coralie M. Reich, Ruidong Xiang, Emily L. Clark, Benjamin G. Cocks, Amanda J. Chamberlain, Iona M. MacLeod and Hans D. Daetwyler
    Citation: BMC Genomics 2022 23:315

    The original article was published in BMC Genomics 2020 21:720

  3. Inonotus obliquus is an important edible and medicinal mushroom that was shown to have many pharmacological activities in preclinical trials, including anti-inflammatory, antitumor, immunomodulatory, and antioxid...

    Authors: Yingce Duan, Haiyan Han, Jianzhao Qi, Jin-ming Gao, Zhichao Xu, Pengchao Wang, Jie Zhang and Chengwei Liu
    Citation: BMC Genomics 2022 23:314
  4. Canga is the Brazilian term for the savanna-like vegetation harboring several endemic species on iron-rich rocky outcrops, usually considered for mining activities. Parkia platycephala Benth. and Stryphnodendron ...

    Authors: Mariana Costa Dias, Cecílio Caldeira, Markus Gastauer, Silvio Ramos and Guilherme Oliveira
    Citation: BMC Genomics 2022 23:313
  5. Dandruff is a chronic, recurring, and common scalp problem that is caused by several etiopathogeneses with complex mechanisms. Management of this condition is typically achieved via antifungal therapies. Howev...

    Authors: Li Wang, Tao Yu, Yaxin Zhu, Yingfeng Luo, Fan Dong, Xuemei Lin, Wenzhong Zhao, Zilong He, Songnian Hu and Zhiyang Dong
    Citation: BMC Genomics 2022 23:312
  6. Deep-sea mussels living in the cold seeps with enormous biomass act as the primary consumers. They are well adapted to the extreme environment where light is absent, and hydrogen sulfide, methane, and other hy...

    Authors: Junrou Huang, Peilin Huang, Jianguo Lu, Nengyou Wu, Genmei Lin, Xilin Zhang, Hong Cao, Wei Geng, Bin Zhai, Cuiling Xu and Zhilei Sun
    Citation: BMC Genomics 2022 23(Suppl 1):311

    This article is part of a Supplement: Volume 23 Supplement 1

  7. Leaf colour mutations are universally expressed at the seedling stage and are ideal materials for exploring the chlorophyll biosynthesis pathway, carotenoid metabolism and the flavonoid biosynthesis pathway in...

    Authors: Tingting Sun, Junke Zhang, Qiang Zhang, Xingliang Li, Minji Li, Yuzhang Yang, Jia Zhou, Qinping Wei and Beibei Zhou
    Citation: BMC Genomics 2022 23:310
  8. Psathyrostachys huashanica Keng has long been used as a genetic resource for improving wheat cultivar because of its genes mediating the resistance to various diseases (stripe rust, leaf rust, take-all, and powd...

    Authors: Hao Zhang, Fei Wang, Chunyan Zeng, Wei Zhu, Lili Xu, Yi Wang, Jian Zeng, Xing Fan, Lina Sha, Dandan Wu, Yiran Cheng, Haiqin Zhang, Guoyue Chen, Yonghong Zhou and Houyang Kang
    Citation: BMC Genomics 2022 23:309
  9. Chicken intramuscular fat (IMF) content is closely related to meat quality and performance, such as tenderness and flavor. Abdominal fat (AF) in chickens is one of the main waste products at slaughter. Excessi...

    Authors: Na Luo, Jingting Shu, Xiaoya Yuan, Yuxi Jin, Huanxian Cui, Guiping Zhao and Jie Wen
    Citation: BMC Genomics 2022 23:308
  10. Advances in genome sequencing technology, particularly restriction-site associated DNA sequence (RAD-seq) and whole-genome resequencing, have greatly aided the construction of cotton interspecific genetic maps...

    Authors: Zhanfeng Si, Shangkun Jin, Jiedan Chen, Sen Wang, Lei Fang, Xiefei Zhu, Tianzhen Zhang and Yan Hu
    Citation: BMC Genomics 2022 23:307
  11. Cattle are considered to be the most desirable livestock by small scale farmers. In Africa, although comprehensive genomic studies have been carried out on cattle, the genetic variations in indigenous cattle f...

    Authors: David H. Mauki, Abdulfatai Tijjani, Cheng Ma, Said I. Ng’ang’a, Akanbi I. Mark, Oscar J. Sanke, Abdussamad M. Abdussamad, Sunday C. Olaogun, Jebi Ibrahim, Philip M. Dawuda, Godwin F. Mangbon, Rudovick R. Kazwala, Paul S. Gwakisa, Ting-Ting Yin, Yan Li, Min-Sheng Peng…
    Citation: BMC Genomics 2022 23:306
  12. Measles caused by measles virus (MeV) is a highly contagious viral disease which has also been associated with complications including pneumonia, myocarditis, encephalitis, and subacute sclerosing panencephali...

    Authors: Suting Wang, Changyin Wang, Xiaodong Liu, Yao Liu, Ping Xiong, Zexin Tao, Meng Chen, Qing Xu, Li Zhang and Aiqiang Xu
    Citation: BMC Genomics 2022 23:305
  13. Intermittent fasting (IF), the implementation of fasting periods of at least 12 consecutive hours on a daily to weekly basis, has received a lot of attention in recent years for imparting the life-prolonging a...

    Authors: Caroline Lindholm, Petros Batakis, Jordi Altimiras and John Lees
    Citation: BMC Genomics 2022 23:304
  14. Many long non-coding RNAs (lncRNAs) have been extensively identified in higher eukaryotic species. The function of lncRNAs has been reported to play important roles in diverse biological processes, including d...

    Authors: Cheng-Hung Tsai, Tzu-Chieh Lin, Yi-Hsien Chang, Huai-Kuang Tsai and Jia-Hsin Huang
    Citation: BMC Genomics 2022 22(Suppl 5):917

    This article is part of a Supplement: Volume 22 Supplement 5

  15. Crohn’s disease is one of the two categories of inflammatory bowel diseases that affect the gastrointestinal tract. The heritability estimate has been reported to be 0.75. Several genes linked to Crohn’s disea...

    Authors: Debora Garza-Hernandez, Maricruz Sepulveda-Villegas, Jose Garcia-Pelaez, Raul Aguirre-Gamboa, Peter L. Lakatos, Karol Estrada, Manuel Martinez-Vazquez and Victor Trevino
    Citation: BMC Genomics 2022 23:302
  16. Nucleosome positioning is the precise determination of the location of nucleosomes on DNA sequence. With the continuous advancement of biotechnology and computer technology, biological data is showing explosiv...

    Authors: Guo-Sheng Han, Qi Li and Ying Li
    Citation: BMC Genomics 2022 23(Suppl 1):301

    This article is part of a Supplement: Volume 23 Supplement 1

  17. The scales serve as an ideal model for studying the regulatory mechanism of bone homeostasis in fish. To explore the effect of salinity acclimation on bone metabolism of juvenile rainbow trout (Oncorhynchus mykis...

    Authors: Qi Ling Zhou, Liu Yong Wang, Xiao Long Zhao, Yun Sheng Yang, Qian Ma and Gang Chen
    Citation: BMC Genomics 2022 23:300
  18. Epigenome analysis relies on defined sets of genomic regions output by widely used assays such as ChIP-seq and ATAC-seq. Statistical analysis and visualization of genomic region sets is essential to answer bio...

    Authors: Kristyna Kupkova, Jose Verdezoto Mosquera, Jason P. Smith, Michał Stolarczyk, Tessa L. Danehy, John T. Lawson, Bingjie Xue, John T. Stubbs IV, Nathan LeRoy and Nathan C. Sheffield
    Citation: BMC Genomics 2022 23:299
  19. Recently genomic selection (GS) has emerged as an important tool for plant breeders to select superior genotypes. Multi-trait (MT) prediction model provides an opportunity to improve the predictive ability of ...

    Authors: Dipendra Shahi, Jia Guo, Sumit Pradhan, Jahangir Khan, Muhsin AVCI, Naeem Khan, Jordan McBreen, Guihua Bai, Matthew Reynolds, John Foulkes and Md Ali Babar
    Citation: BMC Genomics 2022 23:298
  20. The giant panda (Ailuropoda melanoleuca) is a threatened species endemic to China. Alopecia, characterized by thinning and broken hair, mostly occurs in breeding males. Alopecia significantly affects the health a...

    Authors: Haibo Shen, Caiwu Li, Ming He, Yan Huang, Jing Wang, Jing Luo, Minglei Wang, Bisong Yue and Xiuyue Zhang
    Citation: BMC Genomics 2022 23:297
  21. Acoustic communication is important for the survival and reproduction of anurans and masking background noise is a critical factor for their effective acoustic communication. Males of the concave-eared frog (Odor...

    Authors: Zhuo Chen, Yao Liu, Rui Liang, Chong Cui, Yanjun Zhu, Fang Zhang, Jie Zhang and Xiaohong Chen
    Citation: BMC Genomics 2022 23:296
  22. Many transcription factors (TFs), such as multi zinc-finger (ZF) TFs, have multiple DNA binding domains (DBDs), and deciphering the DNA binding motifs of individual DBDs is a major challenge. One example of su...

    Authors: Irene M. Kaplow, Abhimanyu Banerjee and Chuan Sheng Foo
    Citation: BMC Genomics 2022 23:295
  23. Long-term artificial selection for growth rate and lean meat rate has eventually led to meat quality deterioration. Muscle fiber type is a key factor that markedly affects meat quality. circRNAs have been repo...

    Authors: Xiaona Zhuang, Zekun Lin, Fang Xie, Junyi Luo, Ting Chen, Qianyun Xi, Yongliang Zhang and Jiajie Sun
    Citation: BMC Genomics 2022 23:294
  24. Paspalum notatum ‘Flugge’ is a diploid with 20 chromosomes (2n = 20) multi-purpose subtropical herb native to South America and has a high ecological significance. It is currently widely planted in tropical and s...

    Authors: Zhenfei Yan, Huancheng Liu, Yu Chen, Juan Sun, Lichao Ma, Aihua Wang, Fuhong Miao, Lili Cong, Hui Song, Xue Yin, Qi Wang, Yayun Gong, Guofeng Yang and Zengyu Wang
    Citation: BMC Genomics 2022 23:293
  25. VQ motif-containing (VQ) proteins are cofactors of transcriptional regulation that are widely involved in plant growth and development and respond to various stresses. The VQ gene family has been identified an...

    Authors: Lili Zhang, Keke Wang, Yuxuan Han, Luyu Yan, Yan Zheng, Zhenzhen Bi, Xin Zhang, Xiaohong Zhang and Donghong Min
    Citation: BMC Genomics 2022 23:292
  26. Evolutionary conservation is an invaluable tool for inferring functional significance in the genome, including regions that are crucial across many species and those that have undergone convergent evolution. C...

    Authors: Irene M. Kaplow, Daniel E. Schäffer, Morgan E. Wirthlin, Alyssa J. Lawler, Ashley R. Brown, Michael Kleyman and Andreas R. Pfenning
    Citation: BMC Genomics 2022 23:291
  27. Pigeon circovirus (PiCV) infections in pigeons (Columba livia) have been reported worldwide. Currently, pigeon racing is becoming increasingly popular and considered to be a national sport in China, and even, the...

    Authors: Haoran Wang, Hui Gao, Zhiwen Jiang, Leibo Shi, Pengwei Zhao, Yanming Zhang and Chengbao Wang
    Citation: BMC Genomics 2022 23:290
  28. The continued spread of SARS-CoV-2 and emergence of new variants with higher transmission rates and/or partial resistance to vaccines has further highlighted the need for large-scale testing and genomic survei...

    Authors: Alexander Yermanos, Kai-Lin Hong, Andreas Agrafiotis, Jiami Han, Sarah Nadeau, Cecilia Valenzuela, Asli Azizoglu, Roy Ehling, Beichen Gao, Michael Spahr, Daniel Neumeier, Ching-Hsiang Chang, Andreas Dounas, Ezequiel Petrillo, Ina Nissen, Elodie Burcklen…
    Citation: BMC Genomics 2022 23:289
  29. Circular RNA (circRNA), as a new members of noncoding RNA family, have vital functions in many biological processes by as microRNA sponges or competing endogenous RNAs (ceRNAs). However, little has been report...

    Authors: Deyin Zhang, Xiaoxue Zhang, Fadi Li, Xiaolong Li, Yuan Zhao, Yukun Zhang, Liming Zhao, Dan Xu, Jianghui Wang, Xiaobin Yang, Panpan Cui and Weimin Wang
    Citation: BMC Genomics 2022 23:288
  30. The influence of linkage disequilibrium (LD), epistasis, and inbreeding on genotypic variance continues to be an important area of investigation in genetics and evolution. Although the current knowledge about ...

    Authors: José Marcelo Soriano Viana and Antonio Augusto Franco Garcia
    Citation: BMC Genomics 2022 23:286
  31. Spot form net blotch (SFNB) caused by the necrotrophic fungal pathogen Pyrenophora teres f. maculata (Ptm) is an economically important disease of barley that also infects wheat. Using genetic analysis to charact...

    Authors: Shaun J. Clare, Kasia M. Duellman, Jonathan K. Richards, Roshan Sharma Poudel, Lance F. Merrick, Timothy L. Friesen and Robert S. Brueggeman
    Citation: BMC Genomics 2022 23:285
  32. The mitochondrial (mt) genomes of 15 species of sucking lice from seven families have been studied to date. These louse species have highly dynamic, fragmented mt genomes that differ in the number of minichrom...

    Authors: Yalun Dong, Min Zhao and Renfu Shao
    Citation: BMC Genomics 2022 23:283
  33. Bees are the most important group of pollinators worldwide and their populations are declining. In natural conditions, Apis mellifera depends exclusively on food from the field to meet its physiological demands. ...

    Authors: Marcelo Polizel Camilli, Samir Moura Kadri, Marcus Vinícius Niz Alvarez, Paulo Eduardo Martins Ribolla and Ricardo Oliveira Orsi
    Citation: BMC Genomics 2022 23:282
  34. Egg production is one of the most important economic traits in the poultry industry. The hypothalamic-pituitary–gonadal (HPG) axis plays an essential role in regulating reproductive activities. However, the ke...

    Authors: Xiping Yan, Hehe Liu, Jiwei Hu, Xingfa Han, Jingjing Qi, Qingyuan Ouyang, Bo Hu, Hua He, Liang Li, Jiwen Wang and Xianyin Zeng
    Citation: BMC Genomics 2022 23:281
  35. Helictotrichon virescens is a perennial grass that is primarily distributed in high altitude areas of 2000 ~ 4500 m. It is widely cultivated in the Qinghai-Tibet Plateau of China, strongly resistant to cold, and ...

    Authors: Mingjun Cheng, Kuoshu Cui, Mingmin Zheng, Tao Yang, Junjun Zheng, Xiaofeng Li, Xuan Luo, Yang Zhou, Ruizhen Zhang, Donghai Yan, Mingjiu Yao, Muhammad Zafar Iqbal, Qingping Zhou and Ruyu He
    Citation: BMC Genomics 2022 23:280
  36. Salivary gland (SMG) degeneration and dysfunction are common symptoms that occur after sex hormone deprivation, but the underlying mechanisms remain largely unknown. Additionally, immunocastration, which cause...

    Authors: Xingfa Han, Xue Xia, Yong Zhuo, Lun Hua, Guozhi Yu, Guixian Bu, Xiaohan Cao, XiaoGang Du, Qiuxia Liang, Xianyin Zeng and Fengyan Meng
    Citation: BMC Genomics 2022 23:279
  37. Rice sheath blight, caused by Rhizoctonia solani Kühn (teleomorph: Thanatephorus cucumeris), is one of the most severe diseases in rice (Oryza sativa L.) worldwide. Studies on resistance genes and resistance mech...

    Authors: Xiaohe Yang, Xin Gu, Junjie Ding, Liangliang Yao, Xuedong Gao, Maoming Zhang, Qingying Meng, Songhong Wei and Junfan Fu
    Citation: BMC Genomics 2022 23:278
  38. Global climate change together with growing desertification is leading to increased dust emissions to the atmosphere, drawing attention to possible impacts on marine ecosystems receiving dust deposition. Since...

    Authors: Hayedeh Behzad, Hajime Ohyanagi, Badr Alharbi, Martin Ibarra, Mohammed Alarawi, Yoshimoto Saito, Carlos M. Duarte, Vladimir Bajic, Katsuhiko Mineta and Takashi Gojobori
    Citation: BMC Genomics 2022 23:277
  39. Immortalized cell lines are widely used model systems whose genomes are often highly rearranged and polyploid. However, their genome structure is seldom deciphered and is thus not accounted for during analyses...

    Authors: Jacob Lewerentz, Anna-Mia Johansson, Jan Larsson and Per Stenberg
    Citation: BMC Genomics 2022 23:276
  40. Shiga toxin-producing Escherichia coli (STEC) O157:H7 is a pathogen known to reside in cattle feedlots. This retrospective study examined 181 STEC O157:H7 strains collected over 23 years from a closed-system feed...

    Authors: Margaret D. Weinroth, Michael L. Clawson, Terrance M. Arthur, James E. Wells, Dayna M. Brichta-Harhay, Norval Strachan and James L. Bono
    Citation: BMC Genomics 2022 23:275
  41. Cutaneous squamous cell carcinoma (cSCC) is the second most common type of skin cancer, the prognosis for patients with metastatic cSCC remains relatively poor. Thus, there is an urgent need to identify new di...

    Authors: Yu Hu, Rong Li, Hongyin Chen, Lihao Chen, Xuyue Zhou, Linxi Liu, Mei Ju, Kun Chen and Dan Huang
    Citation: BMC Genomics 2022 23:274
  42. Transcription factors (TFs) play central roles in regulating gene expression. With the rapid growth in the use of high-throughput sequencing methods, there is a need to develop a comprehensive data processing ...

    Authors: Guan-Dong Shang, Zhou-Geng Xu, Mu-Chun Wan, Fu-Xiang Wang and Jia-Wei Wang
    Citation: BMC Genomics 2022 23(Suppl 1):272

    This article is part of a Supplement: Volume 23 Supplement 1

  43. The grass carp has great economic value and occupies an important evolutionary position. Genomic information regarding this species could help better understand its rapid growth rate as well as its unique body...

    Authors: Chang-Song Wu, Zi-You Ma, Guo-Dong Zheng, Shu-Ming Zou, Xu-Jie Zhang and Yong-An Zhang
    Citation: BMC Genomics 2022 23:271
  44. Authors: Yanxian Yang, Yongqiang Yang, Mohamed Abd El-Gawad El-Sayed Ahmed, Mingyang Qin, Ruowen He, Yiping Wu, Xiaoxue Liang, Lan-Lan Zhong, Ping Chen, Baoguo Deng, Reem Mostafa Hassan, Weihong Wen, Lingqing Xu, Xubin Huang, Lin Xu and Guo-Bao Tian
    Citation: BMC Genomics 2022 23:270

    The original article was published in BMC Genomics 2022 23:20

  45. Of the > 2600 Salmonella serovars, Salmonella enterica serovar I 4,[5],12:i:- (serovar I 4,[5],12:i:-) has emerged as one of the most common causes of human salmonellosis and the most frequent multidrug-resistant...

    Authors: Julian M. Trachsel, Bradley L. Bearson, Brian W. Brunelle and Shawn M. D. Bearson
    Citation: BMC Genomics 2022 23:268

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