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  1. Cytoplasmic male sterility (CMS) has been widely used for commercial F1 hybrid seeds production. CMS is primarily caused by chimeric genes in mitochondrial genomes. However, which specific stages of anther dev...

    Authors: Xionghui Zhong, Denghui Chen, Jian Cui, Hailong Li, Yuxin Huang and Jungen Kang
    Citation: BMC Genomics 2021 22:646
    Content type: Research Published on:

  2. Limited access to genetic information has greatly hindered our understanding of the molecular evolution, phylogeny, and differentiation time of subg. Amygdalus. This study reported complete chloroplast (cp) genom...

    Authors: Zhongyu Du, Ke Lu, Kai Zhang, Yiming He, Haitao Wang, Guaiqiang Chai, Jianguo Shi and Yizhong Duan
    Citation: BMC Genomics 2021 22:645
    Content type: Research Published on:

  3. Inversion Symmetry is a generalization of the second Chargaff rule, stating that the count of a string of k nucleotides on a single chromosomal strand equals the count of its inverse (reverse-complement) k-mer...

    Authors: Alon Kafri, Benny Chor and David Horn
    Citation: BMC Genomics 2021 22:644
    Content type: Research Published on:

  4. The lower Dipteran fungus fly, Sciara coprophila, has many unique biological features that challenge the rule of genome DNA constancy. For example, Sciara undergoes paternal chromosome elimination and maternal X ...

    Authors: John M. Urban, Michael S. Foulk, Jacob E. Bliss, C. Michelle Coleman, Nanyan Lu, Reza Mazloom, Susan J. Brown, Allan C. Spradling and Susan A. Gerbi
    Citation: BMC Genomics 2021 22:643
    Content type: Research article Published on:

  5. RNA polymerase II plays critical roles in transcription in eukaryotic organisms. C-terminal Domain Phosphatase-like 1 (CPL1) regulates the phosphorylation state of the C-terminal domain of RNA polymerase II su...

    Authors: Chen Yuan, Jingya Xu, Qianqian Chen, Qinggang Liu, Yikai Hu, Yicheng Jin and Cheng Qin
    Citation: BMC Genomics 2021 22:642
    Content type: Research Published on:

  6. Stroke can induce cardiac dysfunction in the absence of primary cardiac disease; however, the mechanisms underlying the interaction between the neurological deficits and the heart are poorly understood. The ob...

    Authors: Jie Chen, Jiahong Gong, Haili Chen, Xuqing Li, Li Wang, Xiaoli Qian, Kecheng Zhou, Ting Wang, Songhe Jiang, Lei Li and Shengcun Li
    Citation: BMC Genomics 2021 22:641
    Content type: Research Published on:

  7. Fatty liver disease prevalently occurs in commercial postpartum dairies, resulting in a worldwide high culling rate because of their subsequent limitations of production and reproduction performance.

    Authors: Letian Zhang, Tingjun Liu, Chengzhang Hu, Xuan Zhang, Qin Zhang and Kerong Shi
    Citation: BMC Genomics 2021 22:640
    Content type: Research Published on:

  8. Resistance of pest insect species to insecticides, including B. thuringiensis (Bt) pesticidal proteins expressed by transgenic plants, is a threat to global food security. Despite the western corn rootworm, Diabr...

    Authors: Brad S. Coates, Emeline Deleury, Aaron J. Gassmann, Bruce E. Hibbard, Lance J. Meinke, Nicholas J. Miller, Jennifer Petzold-Maxwell, B. Wade French, Thomas W. Sappington, Blair D. Siegfried and Thomas Guillemaud
    Citation: BMC Genomics 2021 22:639
    Content type: Research Published on:

  9. LncRNAs are extensively involved in plant biological processes. However, the lack of a comprehensive lncRNA landscape in moso bamboo has hindered the molecular study of lncRNAs. Moreover, the role of lncRNAs i...

    Authors: Jiongliang Wang, Yinguang Hou, Yu Wang and Hansheng Zhao
    Citation: BMC Genomics 2021 22:638
    Content type: Research Published on:

  10. The pond snail, Lymnaea stagnalis (L. stagnalis), has served as a valuable model organism for neurobiology studies due to its simple and easily accessible central nervous system (CNS). L. stagnalis has been widel...

    Authors: Martina Rosato, Brittany Hoelscher, Zhenguo Lin, Chidera Agwu and Fenglian Xu
    Citation: BMC Genomics 2021 22:637
    Content type: Research Published on:

  11. Association mapping studies of quantitative trait loci (QTL) for canine hip dysplasia (CHD) can contribute to the understanding of the genetic background of this common and debilitating disease and might contr...

    Authors: Shizhi Wang, Erling Strandberg, Per Arvelius, Dylan N. Clements, Pamela Wiener and Juliane Friedrich
    Citation: BMC Genomics 2021 22:636
    Content type: Research Published on:

  12. Brine shrimp Artemia have an unequalled ability to endure extreme salinity and complete anoxia. This study aims to elucidate its strategies to cope with these stressors.

    Authors: Stephanie De Vos, Stephane Rombauts, Louis Coussement, Wannes Dermauw, Marnik Vuylsteke, Patrick Sorgeloos, James S. Clegg, Ziro Nambu, Filip Van Nieuwerburgh, Parisa Norouzitallab, Thomas Van Leeuwen, Tim De Meyer, Gilbert Van Stappen, Yves Van de Peer and Peter Bossier
    Citation: BMC Genomics 2021 22:635
    Content type: Research Published on:

  13. The gut microbiota provides health benefits in humans by producing short-chain fatty acids (SCFAs), whose deficiency causes multiple disorders and inflammatory diseases. However, gut bacteria producing SCFAs i...

    Authors: Jing Zhang, Kun Zuo, Chen Fang, Xiandong Yin, Xiaoqing Liu, Jiuchang Zhong, Kuibao Li, Jing Li, Li Xu and Xinchun Yang
    Citation: BMC Genomics 2021 22:634
    Content type: Research Published on:

  14. Halogenation is a recurring feature in natural products, especially those from marine organisms. The selectivity with which halogenating enzymes act on their substrates renders halogenases interesting targets ...

    Authors: Nadia Eusebio, Adriana Rego, Nathaniel R. Glasser, Raquel Castelo-Branco, Emily P. Balskus and Pedro N. Leão
    Citation: BMC Genomics 2021 22:633
    Content type: Research Published on:

  15. As an important group of the multidrug efflux transporter family, the multidrug and toxic compound extrusion (MATE) family has a wide range of functions and is distributed in all kingdoms of living organisms. ...

    Authors: Weihan Zhang, Liao Liao, Jinsheng Xu, Yuepeng Han and Li Li
    Citation: BMC Genomics 2021 22:632
    Content type: Research article Published on:

  16. There exist few, if any, practical guidelines for predictive and falsifiable multi-omic data integration that systematically integrate existing knowledge. Disease modules are popular concepts for interpreting ...

    Authors: Tejaswi V. S. Badam, Hendrik A. de Weerd, David Martínez-Enguita, Tomas Olsson, Lars Alfredsson, Ingrid Kockum, Maja Jagodic, Zelmina Lubovac-Pilav and Mika Gustafsson
    Citation: BMC Genomics 2021 22:631
    Content type: Research article Published on:

  17. Fusarium culmorum is an important pathogen causing head blight of cereals in Europe. This disease is of worldwide importance leading to reduced yield, grain quality, and contamination by mycotoxins. These mycotox...

    Authors: Thomas Miedaner, Andrea Vasquez, Valheria Castiblanco, Hilda Elena Castillo, Nora Foroud, Tobias Würschum and Willmar Leiser
    Citation: BMC Genomics 2021 22:630
    Content type: Research article Published on:

  18. It is believed that natural selection acts on the phenotypical changes caused by mutations. Phenotypically, from fishes to amphibians to reptiles, the emergence of limbs greatly facilitates the landing of anci...

    Authors: Yankai Jiang, Xinyue Cao and Haibin Wang
    Citation: BMC Genomics 2021 22:629
    Content type: Research article Published on:

  20. Streptococcus agalactiae (Group B Streptococcus, GBS) is one of the major bacterial pathogens responsible for neonatal sepsis. Whole genome sequencing has, in recent years, emerged as a reliable tool for capsular...

    Authors: Mienye Bob-Manuel, Lesley McGee, Jeremiah A Igunma, Mary A Alex-Wele, Orikomaba K Obunge and Kennedy T Wariso
    Citation: BMC Genomics 2021 22:627
    Content type: Research Published on:

  21. Long-read sequencing has great promise in enabling portable, rapid molecular-assisted cancer diagnoses. A key challenge in democratizing long-read sequencing technology in the biomedical and clinical community...

    Authors: Shishir Reddy, Ling-Hong Hung, Olga Sala-Torra, Jerald P. Radich, Cecilia CS Yeung and Ka Yee Yeung
    Citation: BMC Genomics 2021 22:626
    Content type: Software Published on:

  22. Genome-wide data are invaluable to characterize differentiation and adaptation of natural populations. Reduced representation sequencing (RRS) subsamples a genome repeatedly across many individuals. However, R...

    Authors: Henrik Christiansen, Franz M. Heindler, Bart Hellemans, Quentin Jossart, Francesca Pasotti, Henri Robert, Marie Verheye, Bruno Danis, Marc Kochzius, Frederik Leliaert, Camille Moreau, Tasnim Patel, Anton P. Van de Putte, Ann Vanreusel, Filip A. M. Volckaert and Isa Schön
    Citation: BMC Genomics 2021 22:625
    Content type: Research Published on:

  23. Finding meaningful gene-gene interaction and the main Transcription Factors (TFs) in co-expression networks is one of the most important challenges in gene expression data mining.

    Authors: Carlos Alberto Oliveira de Biagi Jr, Ricardo Perecin Nociti, Danielle Barbosa Brotto, Breno Osvaldo Funicheli, Patrícia de Cássia Ruy, João Paulo Bianchi Ximenez, David Livingstone Alves Figueiredo and Wilson Araújo Silva Jr
    Citation: BMC Genomics 2021 22:624
    Content type: Software Published on:

  24. The low cost and rapidity of microsatellite analysis have led to the development of several markers for many species. Because in non-invasive genetics it is recommended to genotype individuals using few loci, ...

    Authors: Erminia Scarpulla, Alessio Boattini, Mario Cozzo, Patrizia Giangregorio, Paolo Ciucci, Nadia Mucci, Ettore Randi and Francesca Davoli
    Citation: BMC Genomics 2021 22:623
    Content type: Methodology article Published on:

  25. Sugarcane (Saccharum) is the most critical sugar crop worldwide. As one of the most enriched transcription factor families in plants, MYB genes display a great potential to contribute to sugarcane improvement by ...

    Authors: Yuan Yuan, Xiping Yang, Mengfan Feng, Hongyan Ding, Muhammad Tahir Khan, Jisen Zhang and Muqing Zhang
    Citation: BMC Genomics 2021 22:622
    Content type: Research Published on:

  27. Grass carp (Ctenopharyngodon idella) is one of the most widely cultivated fishes in China. High stocking density can reportedly affect fish growth and immunity. Herein we performed PacBio long-read single-molecul...

    Authors: Yan He, Hongyan Yu, Honggang Zhao, Hua Zhu, Qingjing Zhang, Anqi Wang, Yubang Shen, Xiaoyan Xu and Jiale Li
    Citation: BMC Genomics 2021 22:620
    Content type: Research Published on:

  28. Babesia rossi is a leading cause of morbidity and mortality among the canine population of sub-Saharan Africa, but pathogenesis remains poorly understood. Previous studies of B. rossi infection were derived from ...

    Authors: Rachel L. Smith, Amelia Goddard, Arun Boddapati, Steven Brooks, Johan P. Schoeman, Justin Lack, Andrew Leisewitz and Hans Ackerman
    Citation: BMC Genomics 2021 22:619
    Content type: Research Published on:

  29. Inborn errors of immunity (IEI) are a group of genetic disorders that impair the immune system, with over 400 genes described so far, and hundreds more to be discovered. To facilitate the search for new genes,...

    Authors: Humza A. Khan and Manish J. Butte
    Citation: BMC Genomics 2021 22:618
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2021 22:745

  30. Chestnut seeds are important kinds of edible nuts rich in starch and protein. The characteristics and nutrient contents of chestnut have been found to show obvious metaxenia effects in previous studies. To imp...

    Authors: Shengxing Li, Zhuogong Shi, Qiurong Zhu, Liang Tao, Wenhui Liang and Zhiheng Zhao
    Citation: BMC Genomics 2021 22:617
    Content type: Research article Published on:

  31. The endosymbiont Wolbachia can manipulate arthropod reproduction and invade host populations by inducing cytoplasmic incompatibility (CI). Some host species are coinfected with multiple Wolbachia strains which ma...

    Authors: Jennifer L. Morrow and Markus Riegler
    Citation: BMC Genomics 2021 22:616
    Content type: Research Published on:

  33. Disease resilience, which is the ability of an animal to maintain performance under disease, is important for pigs in commercial herds, where they are exposed to various pathogens. Our objective was to investi...

    Authors: Kyu-Sang Lim, Jian Cheng, Austin Putz, Qian Dong, Xuechun Bai, Hamid Beiki, Christopher K. Tuggle, Michael K. Dyck, Pig Gen Canada, Frederic Fortin, John C. S. Harding, Graham S. Plastow and Jack C. M. Dekkers
    Citation: BMC Genomics 2021 22:614
    Content type: Research article Published on:

  34. Hypertrophic scar (HTS) is a fibroproliferative skin disorder characterized by excessive cell proliferation, migration, and extracellular matrix (ECM) deposition. The CUB and Sushi multiple domains 1 (CSMD1) h...

    Authors: Shuchen Gu, Xin Huang, Xiangwen Xu, Yunhan Liu, Yimin Khoong, Zewei Zhang, Haizhou Li, Yashan Gao and Tao Zan
    Citation: BMC Genomics 2021 22:613
    Content type: Research Published on:

  35. Soil salinization represents a serious threat to global rice production. Although significant research has been conducted to understand salt stress at the genomic, transcriptomic and proteomic levels, few stud...

    Authors: Xiaoyu Yang, Bo Song, Jie Cui, Lina Wang, Shuoshuo Wang, Linlin Luo, Lei Gao, Beixin Mo, Yu Yu and Lin Liu
    Citation: BMC Genomics 2021 22:612
    Content type: Research article Published on:

  36. Potato cyst nematodes belong to the most harmful pathogens in potato, and durable management of these parasites largely depends on host-plant resistances. These resistances are pathotype specific. The current Glo...

    Authors: Joris J.M. van Steenbrugge, Sven van den Elsen, Martijn Holterman, Mark G. Sterken, Peter Thorpe, Aska Goverse, Geert Smant and Johannes Helder
    Citation: BMC Genomics 2021 22:611
    Content type: Research article Published on:

  37. Since the domestication of chicken, various breeds have been developed for food production, entertainment, and so on. Compared to indigenous chicken breeds which generally do not show elite production performa...

    Authors: Xiurong Zhao, Changsheng Nie, Jinxin Zhang, Xinghua Li, Tao Zhu, Zi Guan, Yu Chen, Liang Wang, Xue Ze Lv, Weifang Yang, Yaxiong Jia, Zhonghua Ning, Haiying Li, Changqing Qu, Huie Wang and Lujiang Qu
    Citation: BMC Genomics 2021 22:610
    Content type: Research Published on:

  38. In the animal kingdom, mollusca is an important phylum of the Lophotrochozoa. However, few studies have investigated the molecular cascade of sex determination/early gonadal differentiation within this phylum....

    Authors: Coralie Broquard, Suwansa-ard Saowaros, Mélanie Lepoittevin, Lionel Degremont, Jean-Baptiste Lamy, Benjamin Morga, Abigail Elizur and Anne-Sophie Martinez
    Citation: BMC Genomics 2021 22:609
    Content type: Research article Published on:

  41. The degree to which adaptation to same environment is determined by similar molecular mechanisms, is a topic of broad interest in evolutionary biology, as an indicator of evolutionary predictability. We wished...

    Authors: Sylvie Gimenez, Imène Seninet, Marion Orsucci, Philippe Audiot, Nicolas Nègre, Kiwoong Nam, Réjane Streiff and Emmanuelle d’Alençon
    Citation: BMC Genomics 2021 22:606
    Content type: Research Published on:

  43. Seisonidea (also Seisonacea or Seisonidae) is a group of small animals living on marine crustaceans (Nebalia spec.) with only four species described so far. Its monophyletic origin with mostly free-living wheel a...

    Authors: Katharina M. Mauer, Hanno Schmidt, Marco Dittrich, Andreas C. Fröbius, Sören Lukas Hellmann, Hans Zischler, Thomas Hankeln and Holger Herlyn
    Citation: BMC Genomics 2021 22:604
    Content type: Research Published on:

  44. Alfalfa, the “queen of forage”, is the most extensively cultivated forage legume in the world. The development and yield of alfalfa are seriously limited by abiotic stress. MADS-box transcription factors are o...

    Authors: Xueming Dong, Hao Deng, Wenxue Ma, Qiang Zhou and Zhipeng Liu
    Citation: BMC Genomics 2021 22:603
    Content type: Research Published on:

  45. Grain weight and grain shape are important agronomic traits that affect the grain yield potential and grain quality of rice. Both grain weight and grain shape are controlled by multiple genes. The 3,000 Rice G...

    Authors: Yanan Niu, Tianxiao Chen, Chunchao Wang, Kai Chen, Congcong Shen, Huizhen Chen, Shuangbing Zhu, Zhichao Wu, Tianqing Zheng, Fan Zhang and Jianlong Xu
    Citation: BMC Genomics 2021 22:602
    Content type: Research article Published on:

  46. While recent advances in genomics has enabled vast improvements in the quantification of genome-wide diversity and the identification of adaptive and deleterious alleles in model species, wildlife and non-mode...

    Authors: Georgina Samaha, Claire M. Wade, Hamutal Mazrier, Catherine E. Grueber and Bianca Haase
    Citation: BMC Genomics 2021 22:601
    Content type: Research article Published on:

  47. Nucleotide excision repair is the primary DNA repair mechanism that removes bulky DNA adducts such as UV-induced pyrimidine dimers. Correspondingly, genome-wide mapping of nucleotide excision repair with eXcis...

    Authors: Umit Akkose, Veysel Ogulcan Kaya, Laura Lindsey-Boltz, Zeynep Karagoz, Adam D. Brown, Peter A. Larsen, Anne D. Yoder, Aziz Sancar and Ogun Adebali
    Citation: BMC Genomics 2021 22:600
    Content type: Research article Published on:

  48. Experimental proof of gene function assignments in plants is based on mutant analyses. T-DNA insertion lines provided an invaluable resource of mutants and enabled systematic reverse genetics-based investigati...

    Authors: Boas Pucker, Nils Kleinbölting and Bernd Weisshaar
    Citation: BMC Genomics 2021 22:599
    Content type: Research article Published on:

  49. The typical single-chromosome mitochondrial (mt) genome of animals has fragmented into multiple minichromosomes in the lineage Mitodivisia, which contains most of the parasitic lice of eutherian mammals. These...

    Authors: Wen-Ge Dong, Yalun Dong, Xian-Guo Guo and Renfu Shao
    Citation: BMC Genomics 2021 22:598
    Content type: Research Published on:

  50. Bread wheat (Triticum aestivum L.) is one of the most important cereal food crops for the global population. Spike-layer uniformity (the consistency of the spike distribution in the vertical space)-related traits...

    Authors: Parveen Malik, Jitendra Kumar, Shiveta Sharma, Rajiv Sharma and Shailendra Sharma
    Citation: BMC Genomics 2021 22:597
    Content type: Research article Published on:

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BMC Genomics

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