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  1. Archived formalin fixed paraffin embedded (FFPE) samples are valuable clinical resources to examine clinically relevant morphology features and also to study genetic changes. However, DNA quality and quantity ...

    Authors: Aditya Vijay Bhagwate, Yuanhang Liu, Stacey J. Winham, Samantha J. McDonough, Melody L. Stallings-Mann, Ethan P. Heinzen, Jaime I. Davila, Robert A. Vierkant, Tanya L. Hoskin, Marlene Frost, Jodi M. Carter, Derek C. Radisky, Julie M. Cunningham, Amy C. Degnim and Chen Wang
    Citation: BMC Genomics 2019 20:689
    Content type: Research article Published on:

  2. Tetrastigma hemsleyanum Diels et Gilg is a valuable medicinal herb, whose main bioactive constituents are flavonoids. Chilling sensitivity is the dominant environmental factor limiting growth and development of t...

    Authors: Xin Peng, Hao Wu, Hongjiang Chen, Yujiong Zhang, Dan Qiu and Zhongyi Zhang
    Citation: BMC Genomics 2019 20:687
    Content type: Research article Published on:

  3. Mutations in minor spliceosome components such as U12 snRNA (cerebellar ataxia) and U4atac snRNA (microcephalic osteodysplastic primordial dwarfism type 1 (MOPD1)) result in tissue-specific symptoms. Given tha...

    Authors: Anouk M. Olthof, Katery C. Hyatt and Rahul N. Kanadia
    Citation: BMC Genomics 2019 20:686
    Content type: Research article Published on:

  4. Cancer genomes are peppered with somatic mutations imprinted by different mutational processes. The mutational pattern of a cancer genome can be used to identify and understand the etiology of the underlying m...

    Authors: Erik N. Bergstrom, Mi Ni Huang, Uma Mahto, Mark Barnes, Michael R. Stratton, Steven G. Rozen and Ludmil B. Alexandrov
    Citation: BMC Genomics 2019 20:685
    Content type: Software Published on:

  5. We report the sequencing, assembly and analysis of the genome of the Komodo dragon (Varanus komodoensis), the largest extant lizard, with a focus on antimicrobial host-defense peptides. The Komodo dragon diet inc...

    Authors: Monique L. van Hoek, M. Dennis Prickett, Robert E. Settlage, Lin Kang, Pawel Michalak, Kent A. Vliet and Barney M. Bishop
    Citation: BMC Genomics 2019 20:684
    Content type: Research article Published on:

  7. The brown plant hopper (BPH), Nilaparvata lugens, is one of the major pest of rice (Oryza sativa). Plant defenses against insect herbivores have been extensively studied, but our understanding of insect responses...

    Authors: Jing Zhang, Wei Guan, Chaomei Huang, Yinxia Hu, Yu Chen, Jianping Guo, Cong Zhou, Rongzhi Chen, Bo Du, Lili Zhu, Danax Huanhan and Guangcun He
    Citation: BMC Genomics 2019 20:682
    Content type: Research article Published on:

  8. The crop growth compensation effect is a naturally biological phenomenon, and nitrogen (N) is essential for crop growth and development, especially for yield formation. Little is known about the molecular mech...

    Authors: Qiangqiang Xiong, Lei Zhong, Tianhua Shen, Chaohao Cao, Haohua He and Xiaorong Chen
    Citation: BMC Genomics 2019 20:681
    Content type: Research article Published on:

  9. Fermentation completion is a major prerequisite in many industrial processes involving the bakery yeast Saccharomyces cerevisiae. Stuck fermentations can be due to the combination of many environmental stresses. ...

    Authors: Philippe Marullo, Pascal Durrens, Emilien Peltier, Margaux Bernard, Chantal Mansour and Denis Dubourdieu
    Citation: BMC Genomics 2019 20:680
    Content type: Research article Published on:

  10. Porcine embryos undergo rapid differentiation and expansion between Days 8 and 12 before attaching to the maternal uterine epithelial surface after Day 13. It is known that maternal recognition of pregnancy an...

    Authors: Shuqin Zeng, Jochen Bick, David Kradolfer, Johannes Knubben, Veronika L. Flöter, Stefan Bauersachs and Susanne E. Ulbrich
    Citation: BMC Genomics 2019 20:679
    Content type: Research article Published on:

  11. Light is a key environmental factor in regulation of anthocyanin biosynthesis. Through a large number of bagging screenings, we obtained non-photosensitive eggplants that still have decent amount of anthocyani...

    Authors: Yongjun He, Hang Chen, Lu Zhou, Yang Liu and Huoying Chen
    Citation: BMC Genomics 2019 20:678
    Content type: Research article Published on:

  12. Brain-derived neurotrophic factor (BDNF) is a major signaling molecule that the brain uses to control a vast network of intracellular cascades fundamental to properties of learning and memory, and cognition. W...

    Authors: Kathryn M. Hixson, Meaghan Cogswell, Amy R. Brooks-Kayal and Shelley J. Russek
    Citation: BMC Genomics 2019 20:677
    Content type: Research article Published on:

  13. Herbivorous insects can have a profound impact on plant growth performance. In some years, canopy damage in poplar plantations exceeds 50% of the total leaf surface, thereby possibly compromising carbon fixati...

    Authors: Niels A. Müller, Birgit Kersten, Matthias Fladung and Hilke Schroeder
    Citation: BMC Genomics 2019 20:673
    Content type: Research article Published on:

  14. Single cell transcriptome sequencing has become an increasingly valuable technology for dissecting complex biology at a resolution impossible with bulk sequencing. However, the gap between the technical expert...

    Authors: Di Feng, Charles E. Whitehurst, Dechao Shan, Jon D. Hill and Yong G. Yue
    Citation: BMC Genomics 2019 20:676
    Content type: Software Published on:

  15. The hard tick Hyalomma dromedarii is one of the most injurious ectoparasites affecting camels and apparently best adapted to deserts. As long-term blood feeders, ticks are threatened by host defense system compou...

    Authors: Chaima Bensaoud, Hajer Aounallah, Juliana Mozer Sciani, Fernanda Faria, Ana Marisa Chudzinski-Tavassi, Ali Bouattour and Youmna M’ghirbi
    Citation: BMC Genomics 2019 20:675
    Content type: Research article Published on:

  16. Ethylene signal transduction in plants is conducted by the two-component system (TCS) which consists of histidine kinase (HK), histidine phosphotransferase (HPT) and response regulators (RRs). This system play...

    Authors: Yogeshwar V. Dhar, Deepika Lakhwani, Ashutosh Pandey, Shikha Singh, Prabodh K. Trivedi and Mehar H. Asif
    Citation: BMC Genomics 2019 20:674
    Content type: Research article Published on:

  17. The Yesso scallop, Patinopecten (Mizuhopecten) yessoensis, is a commercially important bivalve in the coastal countries of Northeast Asia. It has complex modes of sex differentiation, but knowledge of the mechani...

    Authors: Liqing Zhou, Zhihong Liu, Yinghui Dong, Xiujun Sun, Biao Wu, Tao Yu, Yanxin Zheng, Aiguo Yang, Qing Zhao and Dan Zhao
    Citation: BMC Genomics 2019 20:671
    Content type: Research article Published on:

  19. Postoperative cognitive dysfunction (POCD) affects a large number of post-surgery patients, especially for the elderly. However, the etiology of this neurocognitive disorder is largely unknown. Even if several...

    Authors: Qiang Liu, Aisheng Hou, Yongyi Zhang, Ying Guo, Jingjing Li, Yinghao Yao, Kaimeng Niu, Hao Li, Yunlong Ma and Jiangbei Cao
    Citation: BMC Genomics 2019 20:670
    Content type: Research article Published on:

  20. Poultry breeding programs have been focused on improvement of growth and carcass traits, however, this has resulted in correlated changes in internal organ weights and increased incidence of metabolic disorder...

    Authors: Gabriel Costa Monteiro Moreira, Mayara Salvian, Clarissa Boschiero, Aline Silva Mello Cesar, James M. Reecy, Thaís Fernanda Godoy, Mônica Corrêa Ledur, Dorian Garrick, Gerson Barreto Mourão and Luiz L. Coutinho
    Citation: BMC Genomics 2019 20:669
    Content type: Research article Published on:

  21. Petal nectar spurs, which facilitate pollination through animal attraction and pollen placement, represent a key innovation promoting diversification in the genus Aquilegia (Ranunculaceae). Identifying the geneti...

    Authors: Evangeline S. Ballerini, Elena M. Kramer and Scott A. Hodges
    Citation: BMC Genomics 2019 20:668
    Content type: Research article Published on:

  22. Histone modifications play a significant role in the regulation of transcription and various biological processes, such as development and regeneration. Though a few genomic (including DNA methylation patterns...

    Authors: Vasudevan Ayyappan, Venkateswara R. Sripathi, Venu ( Kal) Kalavacharla, Malay C. Saha, Jyothi Thimmapuram, Ketaki P. Bhide and Elizabeth Fiedler
    Citation: BMC Genomics 2019 20:667
    Content type: Research article Published on:

  23. The class III peroxidase (PRX) gene family is a plant-specific member of the PRX superfamily that is closely related to various physiological processes, such as cell wall loosening, lignification, and abiotic ...

    Authors: Jun Yan, Peisen Su, Wen Li, Guilian Xiao, Yan Zhao, Xin Ma, Hongwei Wang, Eviatar Nevo and Lingrang Kong
    Citation: BMC Genomics 2019 20:666
    Content type: Research article Published on:

  24. Mosquitoes are colonized by a large but mostly uncharacterized natural virome of RNA viruses, and the composition and distribution of the natural RNA virome may influence the biology and immunity of Anopheles mal...

    Authors: Eugeni Belda, Ferdinand Nanfack-Minkeu, Karin Eiglmeier, Guillaume Carissimo, Inge Holm, Mawlouth Diallo, Diawo Diallo, Amélie Vantaux, Saorin Kim, Igor V. Sharakhov and Kenneth D. Vernick
    Citation: BMC Genomics 2019 20:664
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Genomics 2019 20:698

  25. Iron is an essential micronutrient for the growth and development of virtually all living organisms, playing a pivotal role in the proliferative capability of many bacterial pathogens. The impact that the bioa...

    Authors: Izabela Coimbra Ibraim, Mariana Teixeira Dornelles Parise, Doglas Parise, Michelle Zibetti Tadra Sfeir, Thiago Luiz de Paula Castro, Alice Rebecca Wattam, Preetam Ghosh, Debmalya Barh, Emannuel Maltempi Souza, Aristóteles Góes-Neto, Anne Cybelle Pinto Gomide and Vasco Azevedo
    Citation: BMC Genomics 2019 20:663
    Content type: Research article Published on:

  27. Long non-coding RNAs (LncRNAs) are part of genes, which are not translated into proteins and play a vital role in plant growth and development. Nevertheless, the presence of LncRNAs and how they functions in L...

    Authors: Haron Salih, Wenfang Gong, Shoupu He, Wang Xia, Magwanga Richard Odongo and Xiongming Du
    Citation: BMC Genomics 2019 20:661
    Content type: Research article Published on:

  28. Wheat is the most important staple crop in Afghanistan and accounts for the main part of cereal production. However, wheat production has been unstable during the last decades and the country depends on seed i...

    Authors: S. Dreisigacker, R. K. Sharma, E. Huttner, A. Karimov, M. Q. Obaidi, P. K. Singh, C. Sansaloni, R. Shrestha, K. Sonder and H.-J. Braun
    Citation: BMC Genomics 2019 20:660
    Content type: Research article Published on:

  29. Improving feed efficiency (FE) is a major challenge in pig production. This complex trait is characterized by a high variability. Therefore, the identification of predictors of FE may be a relevant strategy to...

    Authors: Farouk Messad, Isabelle Louveau, Basile Koffi, Hélène Gilbert and Florence Gondret
    Citation: BMC Genomics 2019 20:659
    Content type: Research article Published on:

  30. Inflorescence architecture is denoted by the spatial arrangement of various lateral branches and florets formed on them, which is shaped by a complex of regulators. Unveiling of the regulatory mechanisms under...

    Authors: Qi Wu, Xue Bai, Wei Zhao, Xiaodong Shi, Dabing Xiang, Yan Wan, Xiaoyong Wu, Yanxia Sun, Jianglin Zhao, Lianxin Peng and Gang Zhao
    Citation: BMC Genomics 2019 20:658
    Content type: Research article Published on:

  31. Garlic bulbs are abnormal expanding axillary buds that are rarely found among vascular plants. Bulb-yield is one of the valuable agronomic traits of garlic. However, due to the large genome size and a strictly...

    Authors: Siyuan Zhu, Xiaojun Chen, Xia Liu, Jian Zhao and Touming Liu
    Citation: BMC Genomics 2019 20:657
    Content type: Research article Published on:

  32. Argonaute proteins (AGOs) are important players in the regulation of plant development by directing sRNAs to target mRNAs. In maize (Zea mays), AGO18b is a tassel-enriched and grass-specific AGO. Previous studies...

    Authors: Wei Sun, Dong Chen, Yaqiang Xue, Lihong Zhai, Dan Zhang, Zheng Cao, Lei Liu, Chao Cheng, Yi Zhang and Zuxin Zhang
    Citation: BMC Genomics 2019 20:656
    Content type: Research article Published on:

  33. Adrenocortical adenomas (ACAs) can lead to the autonomous secretion of aldosterone responsible for primary aldosteronism (PA), which is the most common form of secondary arterial hypertension. However, the aut...

    Authors: He Ma, Ranwei Li, Xin Di, Xin Jin, Yan Wang, Bingjie Lai, Cailian Shi, Mingxin Ji, Xinran Zhu and Ke Wang
    Citation: BMC Genomics 2019 20:655
    Content type: Research article Published on:

  34. Data from the 1000 Genomes project is quite often used as a reference for human genomic analysis. However, its accuracy needs to be assessed to understand the quality of predictions made using this reference. ...

    Authors: Saurabh Belsare, Michal Levy-Sakin, Yulia Mostovoy, Steffen Durinck, Subhra Chaudhuri, Ming Xiao, Andrew S. Peterson, Pui-Yan Kwok, Somasekar Seshagiri and Jeffrey D. Wall
    Citation: BMC Genomics 2019 20:620
    Content type: Research article Published on:

  35. Cucurbit yellow stunting disorder virus (CYSDV; genus Crinivirus, Closteroviridae) is transmitted in a semipersistent manner by the whitefly, Bemisia tabaci, and is efficiently transmitted by the widely prevalent...

    Authors: Navneet Kaur, Wenbo Chen, Zhangjun Fei and William M. Wintermantel
    Citation: BMC Genomics 2019 20:654
    Content type: Research article Published on:

  36. Circular RNAs (circRNAs), a class of widely expressed endogenous regulatory RNAs, are involved in diverse physiological and developmental processes in eukaryotic cells. However, there have been no related stud...

    Authors: Xingguo Zhang, Xingli Ma, Longlong Ning, Zhongfeng Li, Kunkun Zhao, Ke Li, Jialin He and Dongmei Yin
    Citation: BMC Genomics 2019 20:653
    Content type: Research article Published on:

  37. Genome-scale metabolic models (GSMM) integrating transcriptomics have been widely used to study cancer metabolism. This integration is achieved through logical rules that describe the association between genes...

    Authors: Igor Marín de Mas, Laura Torrents, Carmen Bedia, Lars K. Nielsen, Marta Cascante and Romà Tauler
    Citation: BMC Genomics 2019 20:652
    Content type: Research article Published on:

  38. The efficient detection and initiation of appropriate response to abiotic stresses are important to plants survival. The plant G-protein coupled receptors (GPCRs) are diverse membranous proteins that are respo...

    Authors: Pu Lu, Richard Odongo Magwanga, Joy Nyangasi Kirungu, Qi Dong, Xiaoyan Cai, Zhongli Zhou, Xingxing Wang, Yanchao Xu, Yuqing Hou, Renhai Peng, Kunbo Wang and Fang Liu
    Citation: BMC Genomics 2019 20:651
    Content type: Research article Published on:

  39. Fusarium crown rot (FCR) is a chronic and severe disease in cereal production in semi-arid regions worldwide. A putative quantitative trait locus conferring FCR resistance, Qcrs.cpi-1H, had previously been mapped...

    Authors: Shang Gao, Zhi Zheng, Jonathan Powell, Ahsan Habib, Jiri Stiller, Meixue Zhou and Chunji Liu
    Citation: BMC Genomics 2019 20:650
    Content type: Research article Published on:

  40. Polyploidy provides a means of interspecific genome transfer to incorporate preferable traits from progenitor to progeny. However, few studies on miRNA expression profiles of interspecific hybrids of B. napus (An...

    Authors: Libin Zhang, Jun Zou, Shisheng Li, Baoshan Wang, Nadia Raboanatahiry and Maoteng Li
    Citation: BMC Genomics 2019 20:649
    Content type: Research article Published on:

  41. The hundred seed weight (HSW) is one of the yield components of soybean [Glycine max (L.) Merrill] and is especially critical for various soybean food types. In this study, a representative sample consisting of 1...

    Authors: Xue Zhao, Hairan Dong, Hong Chang, Jingyun Zhao, Weili Teng, Lijuan Qiu, Wenbin Li and Yingpeng Han
    Citation: BMC Genomics 2019 20:648
    Content type: Research article Published on:

  42. Despite the convergence of rapid technological advances in genomics and the maturing field of ecoimmunology, our understanding of the genes that regulate immunity in wild populations is still nascent. Previous...

    Authors: Cassandra S. Scalf, Julia H. Chariker, Eric C. Rouchka and Noah T. Ashley
    Citation: BMC Genomics 2019 20:647
    Content type: Research article Published on:

  43. The males of many Bactrocera species (Diptera: Tephritidae) respond strongly to plant-derived chemicals (male lures) and can be divided into cue lure/raspberry ketone (CL/RK) responders, methyl eugenol (ME) respo...

    Authors: Zhongzhen Wu, Cong Kang, Mengqiu Qu, Junlong Chen, Mingshun Chen, Shuying Bin and Jintian Lin
    Citation: BMC Genomics 2019 20:646
    Content type: Research article Published on:

  44. Venom has evolved in parallel in multiple animals for the purpose of self-defense, prey capture or both. These venoms typically consist of highly complex mixtures of toxins: diverse bioactive peptides and/or p...

    Authors: Dwin G. B. Grashof, Harald M. I. Kerkkamp, Sandra Afonso, John Archer, D. James Harris, Michael K. Richardson, Freek J. Vonk and Arie van der Meijden
    Citation: BMC Genomics 2019 20:645
    Content type: Research article Published on:

  45. The thermo-sensitive genic male sterility (TGMS) of Brassica napus facilitates reproductive researches and hybrid seed production. Considering the complexity and little information about the molecular mechanism i...

    Authors: Xin Tang, You-Jin Hao, Jun-Xing Lu, Geng Lu and Tao Zhang
    Citation: BMC Genomics 2019 20:644
    Content type: Research article Published on:

  46. Ensifer alkalisoli YIC4027, a recently characterized nitrogen-fixing bacterium of the genus Ensifer, has been isolated from root nodules of the host plant Sesbania cannabina. This plant is widely used as green ma...

    Authors: Xiaoxiao Dang, Zhihong Xie, Wei Liu, Yu Sun, Xiaolin Liu, Yongqiang Zhu and Christian Staehelin
    Citation: BMC Genomics 2019 20:643
    Content type: Research article Published on:

  47. The candidate genus “Methylacidiphilum” comprises thermoacidophilic aerobic methane oxidizers belonging to the Verrucomicrobia phylum. These are the first described non-proteobacterial aerobic methane oxidizer...

    Authors: Thomas Kruse, Chandini Murarilal Ratnadevi, Helge-André Erikstad and Nils-Kåre Birkeland
    Citation: BMC Genomics 2019 20:642
    Content type: Research article Published on:

  48. Although the Y chromosome plays an important role in male sex determination and fertility, it is currently understudied due to its haploid and repetitive nature. Methods to isolate Y-specific contigs from a wh...

    Authors: Samarth Rangavittal, Natasha Stopa, Marta Tomaszkiewicz, Kristoffer Sahlin, Kateryna D. Makova and Paul Medvedev
    Citation: BMC Genomics 2019 20:641
    Content type: Methodology article Published on:

  49. As one of the most important food crops in the world, increasing wheat (Triticum aestivum L.) yield is an urgent task for global food security under the continuous threat of stripe rust (caused by Puccinia striif...

    Authors: Xueling Ye, Jian Li, Yukun Cheng, Fangjie Yao, Li Long, Yuqi Wang, Yu Wu, Jing Li, Jirui Wang, Qiantao Jiang, Houyang Kang, Wei Li, Pengfei Qi, Xiujin Lan, Jian Ma, Yaxi Liu…
    Citation: BMC Genomics 2019 20:640
    Content type: Research article Published on:

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BMC Genomics

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