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  1. The ATP-binding cassette (ABC) transporter superfamily is the largest transporter gene family responsible for transporting specific molecules across lipid membranes in all living organisms. In insects, ABC tra...

    Authors: Shumin Liu, Shun Zhou, Ling Tian, Enen Guo, Yunxia Luan, Jianzhen Zhang and Sheng Li
    Citation: BMC Genomics 2011 12:491
    Content type: Research article Published on:

  2. In eukaryotic organisms, DNA is packaged into chromatin structure, where most of DNA is wrapped into nucleosomes. DNA compaction and nucleosome positioning have clear functional implications, since they modula...

    Authors: Özgen Deniz, Oscar Flores, Federica Battistini, Alberto Pérez, Montserrat Soler-López and Modesto Orozco
    Citation: BMC Genomics 2011 12:489
    Content type: Research article Published on:

  3. The green crab Carcinus maenas is known for its high acclimation potential to varying environmental abiotic conditions. A high ability for ion and acid-base regulation is mainly based on an efficient regulation a...

    Authors: Sandra Fehsenfeld, Rainer Kiko, Yasmin Appelhans, David W Towle, Martin Zimmer and Frank Melzner
    Citation: BMC Genomics 2011 12:488
    Content type: Research article Published on:

  5. Detailed and comprehensive genome annotation can be considered a prerequisite for effective analysis and interpretation of omics data. As such, Gene Ontology (GO) annotation has become a well accepted framewor...

    Authors: Benjamin M Nitsche, Jonathan Crabtree, Gustavo C Cerqueira, Vera Meyer, Arthur FJ Ram and Jennifer R Wortman
    Citation: BMC Genomics 2011 12:486
    Content type: Research article Published on:

  6. Infections with hepatitis C virus (HCV) progress to chronic phase in 80% of patients. To date, the effect produced by HCV on the expression of microRNAs (miRs) involved in the interferon-β (IFN-β) antiviral pa...

    Authors: Roberto Bruni, Cinzia Marcantonio, Elena Tritarelli, Paola Tataseo, Emilia Stellacci, Angela Costantino, Umbertina Villano, Angela Battistini and Anna Rita Ciccaglione
    Citation: BMC Genomics 2011 12:485
    Content type: Research article Published on:

  7. Characterization of population structure and genetic diversity of germplasm is essential for the efficient organization and utilization of breeding material. The objectives of this study were to (i) explore th...

    Authors: Jinquan Li, Ann-Katrin Lühmann, Knuth Weißleder and Benjamin Stich
    Citation: BMC Genomics 2011 12:484
    Content type: Research article Published on:

  8. The study of gene families is pivotal for the understanding of gene evolution across different organisms and such phylogenetic background is often used to infer biochemical functions of genes. Modern high-thro...

    Authors: Thomas Meinel, Michal R Schweiger, Andreas H Ludewig, Ramu Chenna, Sylvia Krobitsch and Ralf Herwig
    Citation: BMC Genomics 2011 12:483
    Content type: Software Published on:

  9. Two strains of the silver fox (Vulpes vulpes), with markedly different behavioral phenotypes, have been developed by long-term selection for behavior. Foxes from the tame strain exhibit friendly behavior towards ...

    Authors: Anna V Kukekova, Jennifer L Johnson, Clotilde Teiling, Lewyn Li, Irina N Oskina, Anastasiya V Kharlamova, Rimma G Gulevich, Ravee Padte, Michael M Dubreuil, Anastasiya V Vladimirova, Darya V Shepeleva, Svetlana G Shikhevich, Qi Sun, Lalit Ponnala, Svetlana V Temnykh, Lyudmila N Trut…
    Citation: BMC Genomics 2011 12:482
    Content type: Research article Published on:

  10. Ascaris suum (large roundworm of pigs) is a parasitic nematode that causes substantial losses to the meat industry. This nematode is suitable for biochemical studies because, unlike C. elegans, homogeneous tissue...

    Authors: Xuan Ma, Yingjie Zhu, Chunfang Li, Yunlong Shang, Fanjing Meng, Shilin Chen and Long Miao
    Citation: BMC Genomics 2011 12:481
    Content type: Research article Published on:

  11. The mechanical properties of wood are largely determined by the orientation of cellulose microfibrils in secondary cell walls. Several genes and their allelic variants have previously been found to affect micr...

    Authors: Xinguo Li, Harry X Wu and Simon G Southerton
    Citation: BMC Genomics 2011 12:480
    Content type: Research article Published on:

  12. Clostridium beijerinckii is an important solvent producing microorganism. The genome of C. beijerinckii NCIMB 8052 has recently been sequenced. Although transcriptome structure is important in order to reveal the...

    Authors: Yi Wang, Xiangzhen Li, Yuejian Mao and Hans P Blaschek
    Citation: BMC Genomics 2011 12:479
    Content type: Research article Published on:

  13. Hundreds of millions of people are infected with cryptosporidiosis annually, with immunocompromised individuals suffering debilitating symptoms and children in socioeconomically challenged regions at risk of r...

    Authors: Jennifer D Artz, Amy K Wernimont, Abdellah Allali-Hassani, Yong Zhao, Mehrnaz Amani, Yu-Hui Lin, Guillermo Senisterra, Gregory A Wasney, Oleg Fedorov, Oliver King, Annette Roos, Vlad V Lunin, Wei Qiu, Patrick Finerty Jr, Ashley Hutchinson, Irene Chau…
    Citation: BMC Genomics 2011 12:478
    Content type: Research article Published on:

  14. An isolate originally labeled Bacillus megaterium CDC 684 was found to contain both pXO1 and pXO2, was non-hemolytic, sensitive to gamma-phage, and produced both the protective antigen and the poly-D-glutamic aci...

    Authors: Richard T Okinaka, Erin P Price, Spenser R Wolken, Jeffrey M Gruendike, Wai Kwan Chung, Talima Pearson, Gary Xie, Chris Munk, Karen K Hill, Jean Challacombe, Bruce E Ivins, James M Schupp, Stephen M Beckstrom-Sternberg, Arthur Friedlander and Paul Keim
    Citation: BMC Genomics 2011 12:477
    Content type: Research article Published on:

  15. The transcription factor MYC is a critical regulator of diverse cellular processes, including both replication and apoptosis. Differences in MYC-regulated gene expression responsible for such opposing outcomes in...

    Authors: Samuel C Robson, Lesley Ward, Helen Brown, Heather Turner, Ewan Hunter, Stella Pelengaris and Michael Khan
    Citation: BMC Genomics 2011 12:476
    Content type: Research article Published on:

  16. The 20-hydroxyecdysone (20E) hierarchy of gene activation serves as an attractive model system for studying the mode of steroid hormone regulated gene expression and development. Many structural analogs of 20E...

    Authors: Sarah E Gonsalves, Scott J Neal, Amy S Kehoe and J Timothy Westwood
    Citation: BMC Genomics 2011 12:475
    Content type: Research article Published on:

  17. Studies of closely related species with different sex chromosome systems can provide insights into the processes of sex chromosome differentiation and evolution. To investigate the potential utility of molecul...

    Authors: Takahito Shikano, Heini M Natri, Yukinori Shimada and Juha Merilä
    Citation: BMC Genomics 2011 12:474
    Content type: Research article Published on:

  18. The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construc...

    Authors: Enrique Sánchez-Molano, Alex Cerna, Miguel A Toro, Carmen Bouza, Miguel Hermida, Belén G Pardo, Santiago Cabaleiro, Jesús Fernández and Paulino Martínez
    Citation: BMC Genomics 2011 12:473
    Content type: Research article Published on:

  19. Burkholderia cenocepacia is a Gram-negative opportunistic pathogen displaying high resistance to antimicrobial peptides and polymyxins. We identified mechanisms of resistance by analyzing transcriptional changes ...

    Authors: Slade A Loutet, Flaviana Di Lorenzo, Chelsea Clarke, Antonio Molinaro and Miguel A Valvano
    Citation: BMC Genomics 2011 12:472
    Content type: Research article Published on:

  20. WRKY proteins are a large family of transcriptional regulators in higher plant. They are involved in many biological processes, such as plant development, metabolism, and responses to biotic and abiotic stress...

    Authors: Jian Ling, Weijie Jiang, Ying Zhang, Hongjun Yu, Zhenchuan Mao, Xingfang Gu, Sanwen Huang and Bingyan Xie
    Citation: BMC Genomics 2011 12:471
    Content type: Research article Published on:

  21. Evolution of the Brassica species has been recursively affected by polyploidy events, and comparison to their relative, Arabidopsis thaliana, provides means to explore their genomic complexity.

    Authors: Xiyin Wang, Manuel J Torres, Gary Pierce, Cornelia Lemke, Lisa K Nelson, Bayram Yuksel, John E Bowers, Barry Marler, Yongli Xiao, Lifeng Lin, Ethan Epps, Heidi Sarazen, Carl Rogers, Santhosh Karunakaran, Jennifer Ingles, Emily Giattina…
    Citation: BMC Genomics 2011 12:470
    Content type: Research article Published on:

  22. Avian pathogenic Escherichia coli (APEC) is detrimental to poultry health and its zoonotic potential is a food safety concern. Regulation of antimicrobials in food-production animals has put greater focus on enha...

    Authors: Erin E Sandford, Megan Orr, Emma Balfanz, Nate Bowerman, Xianyao Li, Huaijun Zhou, Timothy J Johnson, Subhashinie Kariyawasam, Peng Liu, Lisa K Nolan and Susan J Lamont
    Citation: BMC Genomics 2011 12:469
    Content type: Research article Published on:

  23. Research using the Pacific oyster Crassostrea gigas as a model organism has experienced rapid growth in recent years due to the development of high-throughput molecular technologies. As many as 56,268 EST sequenc...

    Authors: Nolwenn M Dheilly, Christophe Lelong, Arnaud Huvet and Pascal Favrel
    Citation: BMC Genomics 2011 12:468
    Content type: Research article Published on:

  24. Bottle gourd [Lagenaria siceraria (Mol.) Standl.] is an important cucurbit crop worldwide. Archaeological research indicates that bottle gourd was domesticated more than 10,000 years ago, making it one of the ear...

    Authors: Pei Xu, Xiaohua Wu, Jie Luo, Baogen Wang, Yonghua Liu, Jeffrey D Ehlers, Sha Wang, Zhongfu Lu and Guojing Li
    Citation: BMC Genomics 2011 12:467
    Content type: Research article Published on:

  25. Genome-wide nucleosome occupancy is negatively related to the average level of transcription factor motif binding based on studies in yeast and several other model organisms. The degree to which nucleosome-mot...

    Authors: Yuanfang Guan, Victoria Yao, Kyle Tsui, Marinella Gebbia, Maitreya J Dunham, Corey Nislow and Olga G Troyanskaya
    Citation: BMC Genomics 2011 12:466
    Content type: Research article Published on:

  27. The creation of lymphoblastoid cell lines (LCLs) through Epstein-Barr virus (EBV) transformation of B-lymphocytes can result in a valuable biomaterial for cell biology research and a renewable source of DNA. W...

    Authors: Eric R Londin, Margaret A Keller, Michael R D'Andrea, Kathleen Delgrosso, Adam Ertel, Saul Surrey and Paolo Fortina
    Citation: BMC Genomics 2011 12:464
    Content type: Research article Published on:

  28. HIP1 Protein Interactor (HIPPI) is a pro-apoptotic protein that induces Caspase8 mediated apoptosis in cell. We have shown earlier that HIPPI could interact with a specific 9 bp sequence motif, defined as the ...

    Authors: Moumita Datta, Ananyo Choudhury, Ansuman Lahiri and Nitai P Bhattacharyya
    Citation: BMC Genomics 2011 12:463
    Content type: Research article Published on:

  29. Photoperiod-sensitive genic male sterile (PGMS) rice, Nongken 58S, was discovered in 1973. It has been widely used for the production of hybrid rice, and great achievements have been made in improving rice yie...

    Authors: Wei Wang, Zhenwei Liu, Zhibin Guo, Gaoyuan Song, Qin Cheng, Daiming Jiang, Yingguo Zhu and Daichang Yang
    Citation: BMC Genomics 2011 12:462
    Content type: Research article Published on:

  30. Adipogenesis is the developmental process by which mesenchymal stem cells (MSC) differentiate into pre-adipocytes and adipocytes. The aim of the study was to analyze the developmental strategies of human bone ...

    Authors: Adriane Menssen, Thomas Häupl, Michael Sittinger, Bruno Delorme, Pierre Charbord and Jochen Ringe
    Citation: BMC Genomics 2011 12:461
    Content type: Research article Published on:

  31. A central aim for studying runs of homozygosity (ROHs) in genome-wide SNP data is to detect the effects of autozygosity (stretches of the two homologous chromosomes within the same individual that are identica...

    Authors: Daniel P Howrigan, Matthew A Simonson and Matthew C Keller
    Citation: BMC Genomics 2011 12:460
    Content type: Methodology article Published on:

  32. Cardiomyopathy syndrome (CMS) is a disease associated with severe myocarditis primarily in adult farmed Atlantic salmon (Salmo salar L.), caused by a double-stranded RNA virus named piscine myocarditis virus (PMC...

    Authors: Gerrit Timmerhaus, Aleksei Krasnov, Pål Nilsen, Marta Alarcon, Sergey Afanasyev, Marit Rode, Harald Takle and Sven Martin Jørgensen
    Citation: BMC Genomics 2011 12:459
    Content type: Research article Published on:

  33. Invasive species are valuable model systems for examining the evolutionary processes and molecular mechanisms associated with their specific characteristics by comparison with closely related species. Over the...

    Authors: Xiao-Wei Wang, Jun-Bo Luan, Jun-Min Li, Yun-Lin Su, Jun Xia and Shu-Sheng Liu
    Citation: BMC Genomics 2011 12:458
    Content type: Research article Published on:

  34. Copy number is a major source of genome variation with important evolutionary implications. Consequently, it is essential to determine copy number variant (CNV) behavior, distributions and frequencies across g...

    Authors: Upeka Samarakoon, Joseph M Gonzales, Jigar J Patel, Asako Tan, Lisa Checkley and Michael T Ferdig
    Citation: BMC Genomics 2011 12:457
    Content type: Research article Published on:

  35. Comparative Genomic Hybridization (CGH) with DNA microarrays has many biological applications including surveys of copy number changes in tumorogenesis, species detection and identification, and functional gen...

    Authors: Luz B Gilbert, Lee Chae, Takao Kasuga and John W Taylor
    Citation: BMC Genomics 2011 12:456
    Content type: Research article Published on:

  36. Biomineralization is a process encompassing all mineral containing tissues produced within an organism. One of the most dynamic examples of this process is the formation of the mollusk shell, comprising a vari...

    Authors: Luke D Gardner, David Mills, Aaron Wiegand, David Leavesley and Abigail Elizur
    Citation: BMC Genomics 2011 12:455
    Content type: Research article Published on:

  37. Cultivated watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai var. lanatus] is an important agriculture crop world-wide. The fruit of watermelon undergoes distinct stages of development with dramatic changes ...

    Authors: Shaogui Guo, Jingan Liu, Yi Zheng, Mingyun Huang, Haiying Zhang, Guoyi Gong, Hongju He, Yi Ren, Silin Zhong, Zhangjun Fei and Yong Xu
    Citation: BMC Genomics 2011 12:454
    Content type: Research article Published on:

  39. Both male and female pigeons have the ability to produce a nutrient solution in their crop for the nourishment of their young. The production of the nutrient solution has been likened to lactation in mammals, ...

    Authors: Meagan J Gillespie, Volker R Haring, Kenneth A McColl, Paul Monaghan, John A Donald, Kevin R Nicholas, Robert J Moore and Tamsyn M Crowley
    Citation: BMC Genomics 2011 12:452
    Content type: Research article Published on:

  40. Sesame is an important oil crop, but limited transcriptomic and genomic data are currently available. This information is essential to clarify the fatty acid and lignan biosynthesis molecular mechanism. In add...

    Authors: Wenliang Wei, Xiaoqiong Qi, Linhai Wang, Yanxin Zhang, Wei Hua, Donghua Li, Haixia Lv and Xiurong Zhang
    Citation: BMC Genomics 2011 12:451
    Content type: Research article Published on:

  41. As scientists continue to pursue various 'omics-based research, there is a need for high quality data for the most fundamental 'omics of all: genomics. The bacterium Paenibacillus larvae is the causative agent of...

    Authors: Queenie WT Chan, R Scott Cornman, Inanc Birol, Nancy Y Liao, Simon K Chan, T Roderick Docking, Shaun D Jackman, Greg A Taylor, Steven JM Jones, Dirk C de Graaf, Jay D Evans and Leonard J Foster
    Citation: BMC Genomics 2011 12:450
    Content type: Research article Published on:

  42. Gene expression assays have been shown to yield high quality genome-wide data from partially degraded RNA samples. However, these methods have not yet been applied to postmortem human brain tissue, despite the...

    Authors: Maggie L Chow, Hai-Ri Li, Mary E Winn, Craig April, Cynthia C Barnes, Anthony Wynshaw-Boris, Jian-Bing Fan, Xiang-Dong Fu, Eric Courchesne and Nicholas J Schork
    Citation: BMC Genomics 2011 12:449
    Content type: Research article Published on:

  43. Elucidation of the pig transcriptome is essential for interpreting functional elements of the genome and understanding the genetic architecture of complex traits such as fat deposition, metabolism and growth.

    Authors: Congying Chen, Huashui Ai, Jun Ren, Wanbo Li, Pinghua Li, Ruimin Qiao, Jing Ouyang, Ming Yang, Junwu Ma and Lusheng Huang
    Citation: BMC Genomics 2011 12:448
    Content type: Research article Published on:

  44. A robust bacterial artificial chromosome (BAC)-based physical map is essential for many aspects of genomics research, including an understanding of chromosome evolution, high-resolution genome mapping, marker-...

    Authors: Yang Zhang, Xiaojun Zhang, Thomas H O'Hare, William S Payne, Jennifer J Dong, Chantel F Scheuring, Meiping Zhang, James J Huang, Mi-Kyung Lee, Mary E Delany, Hong-Bin Zhang and Jerry B Dodgson
    Citation: BMC Genomics 2011 12:447
    Content type: Research article Published on:

  45. Parasitoid insects manipulate their hosts' physiology by injecting various factors into their host upon parasitization. Transcriptomic approaches provide a powerful approach to study insect host-parasitoid int...

    Authors: Kayvan Etebari, Robin W Palfreyman, David Schlipalius, Lars K Nielsen, Richard V Glatz and Sassan Asgari
    Citation: BMC Genomics 2011 12:446
    Content type: Research article Published on:

  46. Cotton fiber length is an important quality attribute to the textile industry and longer fibers can be more efficiently spun into yarns to produce superior fabrics. There is typically a negative correlation be...

    Authors: Doug J Hinchliffe, Rickie B Turley, Marina Naoumkina, Hee Jin Kim, Yuhong Tang, Kathleen M Yeater, Ping Li and David D Fang
    Citation: BMC Genomics 2011 12:445
    Content type: Research article Published on:

  48. Copy neutral loss of heterozygosity (CN-LOH) refers to a special case of LOH occurring without any resulting loss in copy number. These alterations is sometimes seen in tumors as a way to inactivate a tumor su...

    Authors: Hanna Kryh, Helena Carén, Jennie Erichsen, Rose-Marie Sjöberg, Jonas Abrahamsson, Per Kogner and Tommy Martinsson
    Citation: BMC Genomics 2011 12:443
    Content type: Research article Published on:

  49. Doubly Uniparental Inheritance (DUI) is a fascinating exception to matrilinear inheritance of mitochondrial DNA (mtDNA). Species with DUI are characterized by two distinct mtDNAs that are inherited either thro...

    Authors: Marco Passamonti, Andrea Ricci, Liliana Milani and Fabrizio Ghiselli
    Citation: BMC Genomics 2011 12:442
    Content type: Research article Published on:

  50. The developing mouse kidney is currently the best-characterized model of organogenesis at a transcriptional level. Detailed spatial maps have been generated for gene expression profiling combined with systematic

    Authors: Rathi D Thiagarajan, Nicole Cloonan, Brooke B Gardiner, Tim R Mercer, Gabriel Kolle, Ehsan Nourbakhsh, Shivangi Wani, Dave Tang, Keerthana Krishnan, Kylie M Georgas, Bree A Rumballe, Han S Chiu, Jason A Steen, John S Mattick, Melissa H Little and Sean M Grimmond
    Citation: BMC Genomics 2011 12:441
    Content type: Research article Published on:

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BMC Genomics

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