Corder EH, Friedman GD, Vogelman JH, Orentreich N: Seasonal variation in vitamin D, vitamin D-binding protein, and dehydroepiandrosterone: risk of prostate cancer in black and white men. Cancer Epidemiol Biomarkers Prev. 1995, 4: 655-659.
CAS
PubMed
Google Scholar
Schwartz GG, Hulka BS: Is vitamin D deficiency a risk factor for prostate cancer? (Hypothesis). Anticancer Res. 1990, 10: 1307-1311.
CAS
PubMed
Google Scholar
Li H, Stampfer MJ, Hollis JB, Mucci LA, Gaziano JM, Hunter D: A Prospective Study of Plasma Vitamin D Metabolites, Vitamin D Receptor Polymorphisms, and Prostate Cancer. PLoS Med. 2007, 4: e103-10.1371/journal.pmed.0040103.
Article
PubMed Central
PubMed
Google Scholar
Fleet JC: Molecular actions of vitamin D contributing to cancer prevention. Mol Aspects Med. 2008, 29: 388-396. 10.1016/j.mam.2008.07.003.
Article
CAS
PubMed Central
PubMed
Google Scholar
Hedlund TE, Moffatt KA, Miller GJ: Vitamin D receptor expression is required for growth modulation by 1 alpha, 25-dihydroxyvitamin D3 in the human prostatic carcinoma cell line ALAV-31. J Steroid Biochem Mol Biol. 1996, 58: 277-288. 10.1016/0960-0760(96)00030-1.
Article
CAS
PubMed
Google Scholar
Hedlund TE, Moffatt KA, Miller GJ: Stable expression of the nuclear vitamin D receptor in the human prostatic carcinoma cell line JCA-1: Evidence thqt the antiproliferative effects of 1 alpha,25-dihydroxyvitamin D3 are mediated exclusively through the genomic signaling pathway. Endocrinology. 1996, 137: 1554-1561. 10.1210/en.137.5.1554.
CAS
PubMed
Google Scholar
Zhuang SH, Schwartz GG, Cameron D, Burnstein KL: Vitamin D receptor content and transcriptional activity do not fully predict antiproliferative effects of vitamin D in human prostate cancer cell lines. Mol Cell Endocrinol. 1997, 126: 83-90. 10.1016/S0303-7207(96)03974-3.
Article
CAS
PubMed
Google Scholar
Fleet JC, Weaver CM, Heaney RP, Heaney RP: Molecular Regulation of Calcium Metabolism. Calcium in Human Health. 2006, Totowa, NJ: Humana Press, 163-190. full_text.
Chapter
Google Scholar
Liu M, Lee MH, Cohen M, Bommakanti M, Freedman LP: Transcriptional activation of the Cdk inhibitor p21 by vitamin D leads to the induced differentiation of the myelomonocytic cell line U937. Genes and Development. 1996, 10: 142-153. 10.1101/gad.10.2.142.
Article
CAS
PubMed
Google Scholar
Zhuang SH, Burnstein KL: Antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation. Endocrinology. 1998, 139: 1197-1207. 10.1210/en.139.3.1197.
CAS
PubMed
Google Scholar
Boyle BJ, Zhao XY, Cohen P, Feldman D: Insulin-like growth factor binding protein-3 mediates 1 alpha,25- dihydroxyvitamin d(3) growth inhibition in the LNCaP prostate cancer cell line through p21/WAF1. J Urol. 2001, 165: 1319-1324. 10.1016/S0022-5347(01)69892-6.
Article
CAS
PubMed
Google Scholar
Yang L, Yang J, Venkateswarlu S, Ko T, Brattain MG: Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells. J Cell Physiol. 2001, 188: 383-393. 10.1002/jcp.1125.
Article
CAS
PubMed
Google Scholar
Simboli-Campbell M, Narvaez CJ, van Weelden K, Tenniswood M, Welsh J: Comparative effects of 1,25(OH)2D3 and EB1089 on cell cycle kinetics and apoptosis in MCF-7 breast cancer cells. Breast Cancer Res Treat. 1997, 42: 31-41. 10.1023/A:1005772432465.
Article
CAS
PubMed
Google Scholar
Saunders DE, Christensen C, Wappler NL, Schultz JF, Lawrence WD, Malviya VK: Inhibition of c-myc in breast and ovarian carcinoma cells by 1,25-dihydroxyvitamin D3, retinoic acid and dexamethasone. Anticancer Drugs. 1993, 4: 201-208. 10.1097/00001813-199304000-00012.
Article
CAS
PubMed
Google Scholar
Veenstra TD, Windebank AJ, Kumar R: 1,25-dihydroxyvitamin D3 regulates the expression of N-myc, c-myc, protein kinase C, and transforming growth factor-beta2 in neuroblastoma cells. Biochem Biophys Res Commun. 1997, 235: 15-18. 10.1006/bbrc.1997.6718.
Article
CAS
PubMed
Google Scholar
Lin R, Nagai Y, Sladek R, Bastien Y, Ho J, Petrecca K: Expression Profiling in Squamous Carcinoma Cells Reveals Pleiotropic Effects of Vitamin D(3) Analog EB1089 Signaling on Cell Proliferation, Differentiation, and Immune System Regulation. Mol Endocrinol. 2002, 16: 1243-1256. 10.1210/me.16.6.1243.
Article
CAS
PubMed
Google Scholar
Wang TT, Tavera-Mendoza LE, Laperriere D, Libby E, MacLeod NB, Nagai Y: Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol. 2005, 19: 2685-2695. 10.1210/me.2005-0106.
Article
CAS
PubMed
Google Scholar
Krishnan AV, Shinghal R, Raghavachari N, Brooks JD, Peehl DM, Feldman D: Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays. Prostate. 2004, 59: 243-251. 10.1002/pros.20006.
Article
CAS
PubMed
Google Scholar
Qiao S, Tuohimaa P: The role of long-chain fatty-acid-CoA ligase 3 in vitamin D3 and androgen control of prostate cancer LNCaP cell growth. Biochem Biophys Res Commun. 2004, 319: 358-368. 10.1016/j.bbrc.2004.05.014.
Article
CAS
PubMed
Google Scholar
Guzey M, Luo J, Getzenberg RH: Vitamin D3 modulated gene expression patterns in human primary normal and cancer prostate cells. J Cell Biochem. 2004, 93: 271-285. 10.1002/jcb.20182.
Article
CAS
PubMed
Google Scholar
Lambert JR, Kelly JA, Shim M, Huffer WE, Nordeen SK, Baek SJ: Prostate derived factor in human prostate cancer cells: gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth. J Cell Physiol. 2006, 208: 566-574. 10.1002/jcp.20692.
Article
CAS
PubMed
Google Scholar
Peehl DM, Shinghal R, Nonn L, Seto E, Krishnan AV, Brooks JD: Molecular activity of 1,25-dihydroxyvitamin D3 in primary cultures of human prostatic epithelial cells revealed by cDNA microarray analysis. J Steroid Biochem Mol Biol. 2004, 92: 131-141. 10.1016/j.jsbmb.2004.07.003.
Article
CAS
PubMed
Google Scholar
Dai X, Yamasaki K, Yang LJ, Sayama K, Shirakata Y, Tokumara S: Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation. Journal of Investigative Dermatology. 2004, 122: 1356-1364. 10.1111/j.0022-202X.2004.22522.x.
Article
CAS
PubMed
Google Scholar
Palmer HG, Gonzalez-Sancho JM, Espada J, Berciano MT, Puig I, Baulida J: Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol. 2001, 154: 369-387. 10.1083/jcb.200102028.
Article
CAS
PubMed Central
PubMed
Google Scholar
Shah S, Hecht A, Pestell R, Byers SW: Trans-repression of beta-catenin activity by nuclear receptors. Journal of Biological Chemistry. 2003, 278: 48137-48145. 10.1074/jbc.M307154200.
Article
CAS
PubMed
Google Scholar
Leong KG, Gao WQ: The Notch pathway in prostate development and cancer. Differentiation. 2008, 76: 699-716. 10.1111/j.1432-0436.2008.00288.x.
Article
CAS
PubMed
Google Scholar
Santagata S, Demichelis F, Riva A, Varambally S, Hofer MD, Kutok JL: JAGGED1 expression is associated with prostate cancer metastasis and recurrence. Cancer Research. 2004, 64: 6854-6857. 10.1158/0008-5472.CAN-04-2500.
Article
CAS
PubMed
Google Scholar
Zhang YX, Wang ZW, Ahmed F, Banerjee S, Li YW, Sarkar FH: Down-regulation of Jagged-1 induces cell growth inhibition and S phase arrest in prostate cancer cells. International Journal of Cancer. 2006, 119: 2071-2077. 10.1002/ijc.22077.
Article
CAS
Google Scholar
Tosetti F, Ferrari N, De Flora S, Albini A: Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J. 2002, 16: 2-14. 10.1096/fj.01-0300rev.
Article
CAS
PubMed
Google Scholar
Chung I, Han G, Seshadri M, Gillard BM, Yu WD, Foster BA: Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo. Cancer Res. 2009, 69: 967-975. 10.1158/0008-5472.CAN-08-2307.
Article
CAS
PubMed Central
PubMed
Google Scholar
Bao BY, Yao J, Lee YF: 1alpha, 25-dihydroxyvitamin D3 suppresses interleukin-8-mediated prostate cancer cell angiogenesis. Carcinogenesis. 2006, 27: 1883-1893. 10.1093/carcin/bgl041.
Article
CAS
PubMed
Google Scholar
Fernandez-Garcia NI, Palmer HG, Garcia M, Gonzalez-Martin A, del Rio M, Barettino D: 1alpha,25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells. Oncogene. 2005, 24: 6533-6544.
CAS
PubMed
Google Scholar
Campbell CL, Savarese DMF, Quesenberry PJ, Savarese TM: Expression of multiple angiogenic cytokines in cultured normal human prostate epithelial cells: Predominance of vascular endothelial growth factor. International Journal of Cancer. 1999, 80: 868-874. 10.1002/(SICI)1097-0215(19990315)80:6<868::AID-IJC12>3.0.CO;2-1.
Article
CAS
Google Scholar
Cardus A, Panizo S, Encinas M, Dolcet X, Gallego C, Aldea M: 1, 25-Dihydroxyvitamin D3 regulates VEGF production through a vitamin D response element in the VEGF promoter. Atherosclerosis. 2009, 204: 85-89. 10.1016/j.atherosclerosis.2008.08.020.
Article
CAS
PubMed
Google Scholar
Mantell DJ, Owens PE, Bundred NJ, Mawer EB, Canfield AE: 1 alpha, 25-dihydroxyvitamin D(3) inhibits angiogenesis in vitro and in vivo. Circ Res. 2000, 87: 214-220.
Article
CAS
PubMed
Google Scholar
Zhang H, Muders MH, Li J, Rinaldo F, Tindall DJ, Datta K: Loss of NKX3.1 favors vascular endothelial growth factor-C expression in prostate cancer. Cancer Res. 2008, 68: 8770-8778. 10.1158/0008-5472.CAN-08-1912.
Article
CAS
PubMed Central
PubMed
Google Scholar
Gagnon ML, Bielenberg DR, Gechtman Z, Miao HQ, Takashima S, Soker S: Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity. Proceedings of the National Academy of Sciences of the United States of America. 2000, 97: 2573-2578. 10.1073/pnas.040337597.
Article
CAS
PubMed Central
PubMed
Google Scholar
Castro-Rivera E, Ran S, Thorpe P, Minna JD: Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF(165) antagonizes this effect. Proceedings of the National Academy of Sciences of the United States of America. 2004, 101: 11432-11437. 10.1073/pnas.0403969101.
Article
CAS
PubMed Central
PubMed
Google Scholar
Herman JG, Meadows GG: Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells. International Journal of Oncology. 2007, 30: 1231-1238.
CAS
PubMed
Google Scholar
Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M: Free radicals metals and antioxidants in oxidative stress-induced cancer. Chemico-Biological Interactions. 2006, 160: 1-40. 10.1016/j.cbi.2005.12.009.
Article
CAS
PubMed
Google Scholar
Bao BY, Ting HJ, Hsu JW, Lee YF: Protective role of 1 alpha, 25-dihydroxyvitamin D-3 against oxidative stress in nonmalignant human prostate epithelial cells. International Journal of Cancer. 2008, 122: 2699-2706. 10.1002/ijc.23460.
Article
CAS
Google Scholar
Wild AC, Moinova HR, Mulcahy RT: Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. Journal of Biological Chemistry. 1999, 274: 33627-33636. 10.1074/jbc.274.47.33627.
Article
CAS
PubMed
Google Scholar
Frohlich DA, Mccabe MT, Arnold RS, Day ML: The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis. Oncogene. 2008, 27: 4353-4362. 10.1038/onc.2008.79.
Article
CAS
PubMed
Google Scholar
Piemonti L, Monti P, Sironi M, Fraticelli P, Leone BE, Dal Cin E: Vitamin D-3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells. Journal of Immunology. 2000, 164: 4443-4451.
Article
CAS
Google Scholar
Griffin MD, Dong X, Kumar R: Vitamin D receptor-mediated suppression of RelB in antigen presenting cells: a paradigm for ligand-augmented negative transcriptional regulation. Arch Biochem Biophys. 2007, 460: 218-226. 10.1016/j.abb.2007.01.034.
Article
CAS
PubMed Central
PubMed
Google Scholar
Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HFJ, O'Garra A: 1 alpha, 25-dihydroxyvitamin D3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. Journal of Immunology. 2001, 167: 4974-4980.
Article
CAS
Google Scholar
Motrich RD, van Etten E, Depovere J, Riera CM, Rivero VE, Mathieu C: Impact of vitamin D receptor activity on experimental autoimmune prostatitis. Journal of Autoimmunity. 2009, 32: 140-148. 10.1016/j.jaut.2009.02.002.
Article
CAS
PubMed
Google Scholar
Nelson WG, De Marzo AM, DeWeese TL, Isaacs WB: The role of inflammation in the pathogenesis of prostate cancer. J Urol. 2004, 172: S6-11. 10.1097/01.ju.0000142058.99614.ff.
Article
CAS
PubMed
Google Scholar
Mackern-Oberti JP, Maccioni M, Cuffini C, Gatti G, Rivero VE: Susceptibility of prostate epithelial cells to Chlamydia muridarum infection and their role in innate immunity by recruitment of intracellular Toll-like receptors 4 and 2 and MyD88 to the inclusion. Infection and Immunity. 2006, 74: 6973-6981. 10.1128/IAI.00593-06.
Article
CAS
PubMed Central
PubMed
Google Scholar
Schauber J, Oda Y, Buchau AS, Yun QC, Steinmeyer A, Zugel U: Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. J Invest Dermatol. 2008, 128: 816-824. 10.1038/sj.jid.5701102.
Article
CAS
PubMed
Google Scholar
Pfitzner E, Kliem S, Baus D, Litterst CM: The role of STATs in inflammation and inflammatory diseases. Current Pharmaceutical Design. 2004, 10: 2839-2850. 10.2174/1381612043383638.
Article
CAS
PubMed
Google Scholar
Cippitelli M, Santoni A: Vitamin D-3: a transcriptional modulator of the interferon-gamma gene. European Journal of Immunology. 1998, 28: 3017-3030. 10.1002/(SICI)1521-4141(199810)28:10<3017::AID-IMMU3017>3.0.CO;2-6.
Article
CAS
PubMed
Google Scholar
Muthian G, Raikwar HP, Rajasingh J, Bright JJ: 1,25 dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFN gamma axis leading to Th1 response in experimental allergic encephalomyelitis. Journal of Neuroscience Research. 2006, 83: 1299-1309. 10.1002/jnr.20826.
Article
CAS
PubMed
Google Scholar
Nonn L, Peng L, Feldman D, Peehl DM: Inhibition of p38 by vitamin D reduces interleukin-6 production in normal prostate cells via mitogen-activated protein kinase phosphatase 5: implications for prostate cancer prevention by vitamin D. Cancer Res. 2006, 66: 4516-4524. 10.1158/0008-5472.CAN-05-3796.
Article
CAS
PubMed
Google Scholar
Xu Y, Fang F, St Clair DK, Josson S, Sompol P, Spasojevic I: Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha, 25-dihydroxyvitamin D(3) in prostate cancer cells. Mol Cancer Ther. 2007, 6: 2048-2056. 10.1158/1535-7163.MCT-06-0700.
Article
CAS
PubMed Central
PubMed
Google Scholar
Moreno J, Krishnan AV, Feldman D: Molecular mechanisms mediating the anti-proliferative effects of Vitamin D in prostate cancer. J Steroid Biochem Mol Biol. 2005, 97: 31-36. 10.1016/j.jsbmb.2005.06.012.
Article
CAS
PubMed
Google Scholar
Gupta S, Srivastava M, Ahmad N, Bostwick DG, Mukhtar H: Over-expression of cyclooxygenase-2 in Human prostate adenocarcinoma. Prostate. 2000, 42: 73-78. 10.1002/(SICI)1097-0045(20000101)42:1<73::AID-PROS9>3.0.CO;2-G.
Article
CAS
PubMed
Google Scholar
Wu J, Smith LT, Plass C, Huang TH: ChIP-chip comes of age for genome-wide functional analysis. Cancer Res. 2006, 66: 6899-6902. 10.1158/0008-5472.CAN-06-0276.
Article
CAS
PubMed
Google Scholar
Rhim JS, Webber MM, Bello D, Lee MS, Arnstein P, Chen LS: Stepwise immortalization and transformation of adult human prostate epithelial cells by a combination of HPV-18 and v-Ki-ras. Proc Natl Acad Sci USA. 1994, 91: 11874-11878. 10.1073/pnas.91.25.11874.
Article
CAS
PubMed Central
PubMed
Google Scholar
Bolstad BM, Collin F, Brettschneider J, Simpson K, Cope L, Irizarry RA: Quality assessment of Affymetrix GeneChip data. Bioinformatics and Computational Biology Solutions Using R and Bioconductorù. Edited by: Gentleman R, Carey VJ, Huber W, Irizarry RA, Dudoit S. 2005, 42-43.
Google Scholar
Wu ZJ, Irizarry RA, Gentleman R, Martinez-Murillo F, Spencer F: A model-based background adjustment for oligonucleotide expression arrays. Journal of the American Statistical Association. 2004, 99: 909-917. 10.1198/016214504000000683.
Article
Google Scholar
Tusher VG, Tibshirani R, Chu G: Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA. 2001, 98: 5116-5121. 10.1073/pnas.091062498.
Article
CAS
PubMed Central
PubMed
Google Scholar
Benjamini Y, Hochberg Y: Controlling false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc B. 1995, 57: 289-300.
Google Scholar
Doniger SW, Salomonis N, Dahlquist KD, Vranizan K, Lawlor SC, Conklin BR: MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol. 2003, 4: R7-10.1186/gb-2003-4-1-r7.
Article
PubMed Central
PubMed
Google Scholar
Fleet JC, Eksir F, Hance KW, Wood RJ: Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2002, 283: G618-G625.
Article
CAS
PubMed
Google Scholar
Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001, 25: 402-408. 10.1006/meth.2001.1262.
Article
CAS
PubMed
Google Scholar
Cui M, Zhao Y, Hance KW, Shao A, Wood RJ, Fleet JC: Effects of MAPK signaling on 1,25-dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2. J Cell Physiol. 2009, 219: 132-142. 10.1002/jcp.21657.
Article
CAS
PubMed Central
PubMed
Google Scholar
Meyer MB, Watanuki M, Kim S, Shevde NK, Pike JW: The human transient receptor potential vanilloid type 6 distal promoter contains multiple vitamin D receptor binding sites that mediate activation by 1,25-dihydroxyvitamin D3 in intestinal cells. Mol Endocrinol. 2006, 20: 1447-1461. 10.1210/me.2006-0031.
Article
CAS
PubMed
Google Scholar