Shiels B, Langsley G, Weir W, Pain A, McKellar S, Dobbelaere D: Alteration of host cell phenotype by Theileria annulata and Theileria parva: mining for manipulators in the parasite genomes. Int J Parasitol. 2006, 36: 9-21. 10.1016/j.ijpara.2005.09.002.
Article
CAS
PubMed
Google Scholar
Campbell JD, Spooner RL: Macrophages behaving badly: infected cells and subversion of immune responses to Theileria annulata. Parasitol Today. 1999, 15: 10-16. 10.1016/S0169-4758(98)01359-3.
Article
Google Scholar
Preston PM, Hall FR, Glass EJ, Campbell JD, Darghouth MA, Ahmed JS, Shiels BR, Spooner RL, Jongejan F, Brown CG: Innate and adaptive immune responses co-operate to protect cattle against Theileria annulata. Parasitol Today. 1999, 15: 268-274. 10.1016/S0169-4758(99)01466-0.
Article
CAS
PubMed
Google Scholar
Ilhan T, Williamson S, Kirvar E, Shiels B, Brown CG: Theileria annulata: carrier state and immunity. Ann N Y Acad Sci. 1998, 849: 109-125. 10.1111/j.1749-6632.1998.tb11040.x.
Article
CAS
PubMed
Google Scholar
Gharbi M, Sassi L, Dorchies P, Darghouth MA: Infection of calves with Theileria annulata in Tunisia: Economic analysis and evaluation of the potential benefit of vaccination. Vet Parasitol. 2006, 137: 231-241. 10.1016/j.vetpar.2006.01.015.
Article
PubMed
Google Scholar
Preston PM, Darghouth M, Boulter NR, Hall FR, Tall R, Kirvar E, Brown CG: A dual role for immunosuppressor mechanisms in infection with Theileria annulata: well-regulated suppressor macrophages help in recovery from infection; profound immunosuppression promotes non-healing disease. Parasitol Res. 2002, 88: 522-534. 10.1007/s00436-002-0613-8.
Article
PubMed
Google Scholar
Pain A, Renauld H, Berriman M, Murphy L, Yeats CA, Weir W, Kerhornou A, Aslett M, Bishop R, Bouchier C: Genome of the host-cell transforming parasite Theileria annulata compared with T. parva. Science. 2005, 309: 131-133. 10.1126/science.1110418.
Article
CAS
PubMed
Google Scholar
Endo T, Ikeo K, Gojobori T: Large-scale search for genes on which positive selection may operate. Mol Biol Evol. 1996, 13: 685-690.
Article
CAS
PubMed
Google Scholar
Conway DJ, Polley SD: Measuring immune selection. Parasitology. 2002, 125: S3-16. 10.1017/S0031182002002214.
Article
PubMed
Google Scholar
Katzer F, McKellar S, Ben Miled L, d'Oliveira C, Shiels B: Selection for antigenic diversity of Tams1, the major merozoite antigen of Theileria annulata. Ann N Y Acad Sci. 1998, 849: 96-108. 10.1111/j.1749-6632.1998.tb11039.x.
Article
CAS
PubMed
Google Scholar
Boulter N, Hall R: Immunity and vaccine development in the bovine theilerioses. Adv Parasitol. 2000, 44: 41-97. full_text.
Article
Google Scholar
Katzer F, Carrington M, Knight P, Williamson S, Tait A, Morrison IW, Hall R: Polymorphism of SPAG-1, a candidate antigen for inclusion in a sub-unit vaccine against Theileria annulata. Mol Biochem Parasitol. 1994, 67: 1-10. 10.1016/0166-6851(94)90090-6.
Article
CAS
PubMed
Google Scholar
Shiels BR, McKellar S, Katzer F, Lyons K, Kinnaird J, Ward C, Wastling JM, Swan D: A Theileria annulata DNA binding protein localized to the host cell nucleus alters the phenotype of a bovine macrophage cell line. Eukaryot Cell. 2004, 3: 495-505. 10.1128/EC.3.2.495-505.2004.
Article
CAS
PubMed Central
PubMed
Google Scholar
Swan DG, Stern R, McKellar S, Phillips K, Oura CA, Karagenc TI, Stadler L, Shiels BR: Characterisation of a cluster of genes encoding Theileria annulata AT hook DNA-binding proteins and evidence for localisation to the host cell nucleus. J Cell Sci. 2001, 114: 2747-2754.
CAS
PubMed
Google Scholar
Weir W, Sunter J, Chaussepied M, Skilton R, Tait A, de Villiers EP, Bishop R, Shiels B, Langsley G: Highly syntenic and yet divergent: a tale of two Theilerias. Infect Genet Evol. 2009, 9: 453-461. 10.1016/j.meegid.2009.01.002.
Article
CAS
PubMed
Google Scholar
Oura CA, McKellar S, Swan DG, Okan E, Shiels BR: Infection of bovine cells by the protozoan parasite Theileria annulata modulates expression of the ISGylation system. Cell Microbiol. 2006, 8: 276-288. 10.1111/j.1462-5822.2005.00620.x.
Article
CAS
PubMed
Google Scholar
Moreno S, Nurse P: Substrates for p34cdc2: in vivo veritas?. Cell. 1990, 61: 549-551. 10.1016/0092-8674(90)90463-O.
Article
CAS
PubMed
Google Scholar
Rechsteiner M, Rogers SW: PEST sequences and regulation by proteolysis. Trends Biochem Sci. 1996, 21: 267-271.
Article
CAS
PubMed
Google Scholar
The T. annulata genome browser. [http://www.genedb.org/]
Schmuckli-Maurer J, Casanova C, Schmied S, Affentranger S, Parvanova I, Kang'a S, Nene V, Katzer F, McKeever D, Muller J: Expression analysis of the Theileria parva subtelomere-encoded variable secreted protein gene family. PLoS ONE. 2009, 4: e4839-10.1371/journal.pone.0004839.
Article
PubMed Central
PubMed
Google Scholar
Horn D: Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids. BMC Genomics. 2008, 9: 2-10.1186/1471-2164-9-2.
Article
PubMed Central
PubMed
Google Scholar
Swan DG, Phillips K, Tait A, Shiels BR: Evidence for localisation of a Theileria parasite AT hook DNA-binding protein to the nucleus of immortalised bovine host cells. Mol Biochem Parasitol. 1999, 101: 117-129. 10.1016/S0166-6851(99)00064-X.
Article
CAS
PubMed
Google Scholar
Gardner MJ, Bishop R, Shah T, de Villiers EP, Carlton JM, Hall N, Ren Q, Paulsen IT, Pain A, Berriman M: Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes. Science. 2005, 309: 134-137. 10.1126/science.1110439.
Article
CAS
PubMed
Google Scholar
Aravind L, Landsman D: AT-hook motifs identified in a wide variety of DNA-binding proteins. Nucleic Acids Res. 1998, 26: 4413-4421. 10.1093/nar/26.19.4413.
Article
CAS
PubMed Central
PubMed
Google Scholar
Ahmed JS, Mehlhorn H: Review: the cellular basis of the immunity to and immunopathogenesis of tropical theileriosis. Parasitol Res. 1999, 85: 539-549. 10.1007/s004360050593.
Article
CAS
PubMed
Google Scholar
Morrison WI, McKeever DJ: Immunology of infections with Theileria parva in cattle. Chem Immunol. 1998, 70: 163-185. full_text.
Article
PubMed
Google Scholar
Kubota R, Hanada K, Furukawa Y, Arimura K, Osame M, Gojobori T, Izumo S: Genetic stability of human T lymphotropic virus type I despite antiviral pressures by CTLs. J Immunol. 2007, 178: 5966-5972.
Article
CAS
PubMed
Google Scholar
McKeever DJ: Bovine immunity - a driver for diversity in Theileria parasites?. Trends Parasitol. 2009, 25: 269-276. 10.1016/j.pt.2009.03.005.
Article
CAS
PubMed
Google Scholar
Donelson JE: Antigenic variation and the African trypanosome genome. Acta Trop. 2003, 85: 391-404. 10.1016/S0001-706X(02)00237-1.
Article
CAS
PubMed
Google Scholar
Barry AE, Leliwa-Sytek A, Tavul L, Imrie H, Migot-Nabias F, Brown SM, McVean GA, Day KP: Population genomics of the immune evasion (var) genes of Plasmodium falciparum. PLoS Pathog. 2007, 3: e34-10.1371/journal.ppat.0030034.
Article
PubMed Central
PubMed
Google Scholar
Swan DG, Stadler L, Okan E, Hoffs M, Katzer F, Kinnaird J, McKellar S, Shiels BR: TashHN, a Theileria annulata encoded protein transported to the host nucleus displays an association with attenuation of parasite differentiation. Cell Microbiol. 2003, 5: 947-956. 10.1046/j.1462-5822.2003.00340.x.
Article
CAS
PubMed
Google Scholar
Yie J, Liang S, Merika M, Thanos D: Intra- and intermolecular cooperative binding of high-mobility-group protein I(Y) to the beta-interferon promoter. Mol Cell Biol. 1997, 17: 3649-3662.
Article
CAS
PubMed Central
PubMed
Google Scholar
Ahmed JS, Schnittger L, Mehlhorn H: Review: Theileria schizonts induce fundamental alterations in their host cells. Parasitol Res. 1999, 85: 527-538. 10.1007/s004360050592.
Article
CAS
PubMed
Google Scholar
Graham SP, Brown DJ, Vatansever Z, Waddington D, Taylor LH, Nichani AK, Campbell JD, Adamson RE, Glass EJ, Spooner RL: Proinflammatory cytokine expression by Theileria annulata infected cell lines correlates with the pathology they cause in vivo. Vaccine. 2001, 19: 2932-2944. 10.1016/S0264-410X(00)00529-6.
Article
CAS
PubMed
Google Scholar
Dobbelaere D, Heussler V: Transformation of leukocytes by Theileria parva and T. annulata. Annu Rev Microbiol. 1999, 53: 1-42. 10.1146/annurev.micro.53.1.1.
Article
CAS
PubMed
Google Scholar
Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG: The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 1997, 25: 4876-4882. 10.1093/nar/25.24.4876.
Article
CAS
PubMed Central
PubMed
Google Scholar
Page RD: TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci. 1996, 12: 357-358.
CAS
PubMed
Google Scholar
Carver TJ, Rutherford KM, Berriman M, Rajandream MA, Barrell BG, Parkhill J: ACT: the Artemis Comparison Tool. Bioinformatics. 2005, 21: 3422-3423. 10.1093/bioinformatics/bti553.
Article
CAS
PubMed
Google Scholar
Nielsen H, Engelbrecht J, Brunak S, von Heijne G: Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 1997, 10: 1-6. 10.1093/protein/10.1.1.
Article
CAS
PubMed
Google Scholar
Bendtsen JD, Nielsen H, von Heijne G, Brunak S: Improved prediction of signal peptides: SignalP 3.0. J Mol Biol. 2004, 340: 783-795. 10.1016/j.jmb.2004.05.028.
Article
PubMed
Google Scholar
Krogh A, Larsson B, von Heijne G, Sonnhammer EL: Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol. 2001, 305: 567-580. 10.1006/jmbi.2000.4315.
Article
CAS
PubMed
Google Scholar
von Heijne G: A new method for predicting signal sequence cleavage sites. Nucleic Acids Res. 1986, 14: 4683-4690. 10.1093/nar/14.11.4683.
Article
CAS
PubMed Central
PubMed
Google Scholar
Cokol M, Nair R, Rost B: Finding nuclear localization signals. EMBO Rep. 2000, 1: 411-415. 10.1093/embo-reports/kvd092.
Article
CAS
PubMed Central
PubMed
Google Scholar
Rogers S, Wells R, Rechsteiner M: Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science. 1986, 234: 364-368. 10.1126/science.2876518.
Article
CAS
PubMed
Google Scholar
Enright AJ, Van Dongen S, Ouzounis CA: An efficient algorithm for large-scale detection of protein families. Nucleic Acids Res. 2002, 30: 1575-1584. 10.1093/nar/30.7.1575.
Article
CAS
PubMed Central
PubMed
Google Scholar
Weir W: Genomic and population genetic studies on Theileria annulata. PhD Thesis. 2006, University of Glasgow
Google Scholar
Weir W, Ben Miled L, Karagenc T, Katzer F, Darghouth M, Shiels B, Tait A: Genetic exchange and sub-structuring in Theileria annulata populations. Mol Biochem Parasitol. 2007, 154: 170-180. 10.1016/j.molbiopara.2007.04.015.
Article
CAS
PubMed
Google Scholar
MacLeod A, Tweedie A, Welburn SC, Maudlin I, Turner CM, Tait A: Minisatellite marker analysis of Trypanosoma brucei: reconciliation of clonal, panmictic, and epidemic population genetic structures. Proc Natl Acad Sci USA. 2000, 97: 13442-13447. 10.1073/pnas.230434097.
Article
CAS
PubMed Central
PubMed
Google Scholar
Rozas J, Sanchez-DelBarrio JC, Messeguer X, Rozas R: DnaSP, DNA polymorphism analyses by the coalescent and other methods. Bioinformatics. 2003, 19: 2496-2497. 10.1093/bioinformatics/btg359.
Article
CAS
PubMed
Google Scholar
Fu YX, Li WH: Statistical tests of neutrality of mutations. Genetics. 1993, 133: 693-709.
CAS
PubMed Central
PubMed
Google Scholar
Tajima F: Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics. 1989, 123: 585-595.
CAS
PubMed Central
PubMed
Google Scholar
McDonald JH, Kreitman M: Adaptive protein evolution at the Adh locus in Drosophila. Nature. 1991, 351: 652-654. 10.1038/351652a0.
Article
CAS
PubMed
Google Scholar
Rand DM, Kann LM: Excess amino acid polymorphism in mitochondrial DNA: contrasts among genes from Drosophila, mice, and humans. Mol Biol Evol. 1996, 13: 735-748.
Article
CAS
PubMed
Google Scholar
Pond SL, Frost SD: Not so different after all: a comparison of methods for detecting amino acid sites under selection. Mol Biol Evol. 2005, 22: 1208-1222. 10.1093/molbev/msi105.
Article
CAS
Google Scholar
Pond SL, Frost SD, Muse SV: HyPhy: hypothesis testing using phylogenies. Bioinformatics. 2005, 21: 676-679. 10.1093/bioinformatics/bti079.
Article
CAS
PubMed
Google Scholar
Peakall R, Smouse PE: GENALEX6: genetic analysis in Excel. Population genetic software for teaching and research. Molecular Ecology Notes. 2006, 6: 288-295. 10.1111/j.1471-8286.2005.01155.x.
Article
Google Scholar