Dhawale A. Abnormal eggs cause subnormal profits. World Poult. 2008;24(6):20–3.
Google Scholar
Ren ZZ, Piepenburg AJ, Bütz DE, Claus JR, Cook ME. Vaccine to fibroblast growth factor 23 peptides increases eggshell strength. Poult Sci. 2018;97(3):882–9.
Article
CAS
PubMed
Google Scholar
Fathi MM, Galal A, Ali UM, Abou-Emera OK. Physical and mechanical properties of eggshell as affected by chicken breed and flock age. Br Poult Sci. 2019;60(5):506–12.
Article
CAS
PubMed
Google Scholar
Travel A, Nys Y, Bain MM. Effect of hen age, moult, laying environment and egg storage on egg quality. In: Nys Y, Bain M, van Immerseel F, editors. Improving the safety and quality of eggs and egg products. Cambridge: Woodhead Publishing limited; 2011. p. 300–29.
Chapter
Google Scholar
Bain MM, Nys Y, Dunn IC. Increasing persistency in lay and stabilising egg quality in longer laying cycles. What are the challenges? Br Poult Sci. 2016;57(3):330–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ketta M, Tůmova E. Eggshell structure, measurements, and quality-affecting factors in laying hens: a review. Czech J Anim Sci. 2016;61(7):299–309.
Article
Google Scholar
Athanasiadou D, Jiang W, Goldbaum D, Saleem A, Basu K, Pacella MS, Böhm CF, Chromik RR, Hincke MT, Rodríguez-Navarro AB, Vali H, Wolf SE, Gray JJ, Bui KH, McKee MD. Nanostructure, osteopontin, and mechanical properties of calcitic avian eggshell. Sci Adv. 2018;4:eaar3219.
Article
PubMed
PubMed Central
CAS
Google Scholar
Park JA, Sohn SH. The influence of hen aging on eggshell ultrastructure and shell mineral components. Korean J Food Sci Anim Resour. 2018;38(5):1080–91.
Article
PubMed
PubMed Central
Google Scholar
Hincke MT, Nys Y, Gautron J, Mann K, Rodriguez-Navarro AB, Mckee MD. The eggshell: structure, composition and mineralization. Front Biosci. 2012;17(1):1266–80.
Article
CAS
Google Scholar
Marie P, Labas V, Brionne A, Harichaux G, Hennequet-Antier C, Rodriguez-Navarro AB, Nys Y, Gautron J. Quantitative proteomics provides new insights into chicken eggshell matrix protein functions during the primary events of mineralisation and the active calcification phase. J Proteome. 2015;126:140–54.
Article
CAS
Google Scholar
Gautron J. Proteomics analysis of avian eggshell matrix proteins: toward new advances on biomineralisation. Proteomics. 2019;19(13):1900120.
Article
CAS
Google Scholar
Jeong W, Lim W, Kim J, Ahn SE, Lee HC, Jeong JW, Han JY, Song G, Bazer FW. Cell-specific and temporal aspects of gene expression in the chicken oviduct at different stages of the laying cycle. Biol Reprod. 2012;86(6):172.
Article
PubMed
CAS
Google Scholar
Khan S, Wu SB, Roberts J. RNA-sequencing analysis of shell gland shows differences in gene expression profile at two time-points of eggshell formation in laying chickens. BMC Genomics. 2019;20(1):89.
Article
PubMed
PubMed Central
Google Scholar
Brionne A, Nys Y, Hennequet-Antier C, Gautron J. Hen uterine gene expression profiling during eggshell formation reveals putative proteins involved in the supply of minerals or in the shell mineralization process. BMC Genomics. 2014;15:220.
Article
PubMed
PubMed Central
CAS
Google Scholar
Sah N, Kuehu DL, Khadka VS, Deng YP, Peplowska K, Jha R, Mishra B. RNA sequencing-based analysis of the laying hen uterus revealed the novel genes and biological pathways involved in the eggshell biomineralization [J]. Sci Rep. 2018;8(1):16853.
Article
PubMed
PubMed Central
CAS
Google Scholar
Zhang Q, Zhu F, Liu L, Zheng CW, Wang DH, Hou ZC, Ning ZH. Integrating transcriptome and genome re-sequencing data to identify key genes and mutations affecting chicken eggshell qualities. PLoS One. 2015;10(5):e0125890.
Article
PubMed
PubMed Central
CAS
Google Scholar
Dunn IC, Joseph NT, Bain M, Edmond A, Wilson PW, Milona P, Nys Y, Gautron J, Schmutz M, Preisinger R, Waddington D. Polymorphisms in eggshell organic matrix genes are associated with eggshell quality measurements in pedigree Rhode Island red hens. Anim Genet. 2009;40(1):110–4.
Article
CAS
PubMed
Google Scholar
Duan Z, Sun C, Shen M, Wang K, Yang N, Zheng J, Xu G. Genetic architecture dissection by genome-wide association analysis reveals avian eggshell ultrastructure traits. Sci Rep. 2016;6:28836.
Article
CAS
PubMed
PubMed Central
Google Scholar
Park JA, Cho EJ, Park JY, Sohn SH. Histological change of uterus endometrium and expression of the eggshell-related genes according to hen age. Korean J Poult Sci. 2017;44(1):19–28.
Article
Google Scholar
Veronika G, Monika P, Ivan M, Eva T. Concentration of egg white antimicrobial and immunomodulatory proteins is related to eggshell pigmentation across traditional chicken breeds. Poult Sci. 2019;98(12):6931–41.
Article
CAS
Google Scholar
Panheleux M, Nys Y, Williams J, Gautron J, Boldicke T, Hincke MT. Extraction and quantification by ELISA of eggshell organic matrix proteins (ovocleidin-17, ovalbumin, ovotransferrin) in shell from young and old hens. Poult Sci. 2000;79(4):580–8.
Article
CAS
PubMed
Google Scholar
Anna W, Yvonne R, Helena W, Lena H. Age-related changes in the shell gland and duodenum in relation to shell quality and bone strength in commercial laying hen hybrids. Acta Vet Scand. 2019;61(1):14.
Article
Google Scholar
Sirri F, Zampiga M, Berardinelli A, Meluzzi A. Variability and interaction of some egg physical and eggshell quality attributes during the entire laying hen cycle. Poult Sci. 2018;97(5):1818–23.
Article
CAS
PubMed
Google Scholar
Kemps B, Govaerts T, De Ketelaere B, Mertens K, Bamelis F, Bain MM, Decuypere E, De Baerdemaeker J. The influence of line and laying period on the relationship between different eggshell and membrane strength parameters. Poult Sci. 2006;85(7):1309–17.
Article
CAS
PubMed
Google Scholar
Radwan LM. Eggshell quality: a comparison between Fayoumi, Gimieizah and Brown Hy-line strains for mechanical properties and ultrastructure of their eggshells. Anim Prod Sci. 2015;56(5):908–12.
Article
Google Scholar
Dunn IC, Rodríguez-Navarro AB, Mcdade K, Schmutz M, Preisinger R, Waddington D, Wilson PW, Bain MM. Genetic variation in eggshell crystal size and orientation is large and these traits are correlated with shell thickness and are associated with eggshell matrix protein markers. Anim Genet. 2012;43(4):410–8.
Article
CAS
PubMed
Google Scholar
Arias JI, Jure C, Wiff JP, Fernández MS, Fuenzalida V, Arias JL. Effect of sulfate content of biomacromolecules on the crystallization of calcium carbonate. Mrs Proc. 2001;711:HH1.7.1.
Article
Google Scholar
Yin L, Yu L, Zhang L, Ran J, Li J, Yang C, Jiang X, Du H, Hu X, Liu Y. Transcriptome analysis reveals differentially expressed genes and pathways for oviduct development and defense in prelaying and laying hens. Am J Reprod Immunol. 2019;82(3):e13159.
Article
PubMed
CAS
Google Scholar
Mortensen OV. MKP3 eliminates depolarization-dependent neurotransmitter release through downregulation of L-type calcium channel Cav1.2 expression. Cell Calcium. 2013;53(3):224–30.
Article
CAS
PubMed
Google Scholar
Zhang J, Wang Y, Zhang C, Xiong M, Rajput SA, Liu Y, Qi D. The differences of gonadal hormones and uterine transcriptome during shell calcification of hens laying hard or weak-shelled eggs. BMC Genomics. 2019;20(1):707.
Article
PubMed
PubMed Central
CAS
Google Scholar
Kondapalli KC, Llongueras JP, Capilla-González V, Prasad H, Hack A, Smith C, Guerrero-Cázares H, Quiñones-Hinojosa A, Rao R. A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma. Nat Commun. 2015;6:6289.
Article
CAS
PubMed
PubMed Central
Google Scholar
Marie P, Labas V, Brionne A, Harichaux G, Hennequet-Antier C, Nys Y, Gautron J. Quantitative proteomics and bioinformatic analysis provide new insight into protein function during avian eggshell biomineralization. J Proteome. 2015;113:178–93.
Article
CAS
Google Scholar
Wolf SE, Leiterer J, Pipich V, Barrea R, Emmerling F, Tremel W. Strong stabilization of amorphous calcium carbonate emulsion by ovalbumin: gaining insight into the mechanism of 'polymer-induced liquid precursor' processes. J Am Chem Soc. 2011;133(32):12642–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang X, Wu C, Tao K, Zhao K, Wang J, Xu H, Xia D, Shan H, Lu JR. Influence of ovalbumin on CaCO3 precipitation during in vitro biomineralization. J Phys Chem B. 2010;114(16):5301–8.
Article
CAS
PubMed
Google Scholar
Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Yan H, Deloukas P, Soranzo N, Chinnapenhorsley U, Cervino A, Williams FM, Xiong DH, Zhang YP, Jin TB, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Spector TM, Deng HW. Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS One. 2008;3(9):e3160.
Article
PubMed
PubMed Central
CAS
Google Scholar
Nagchowdhuri PS, Andrews KN, Robart S, Capehart AA. Versican knockdown reduces interzone area during early stages of chick synovial joint development. Anat Rec. 2012;295(3):397–409.
Article
CAS
Google Scholar
Marie PJ. Role of N-cadherin in bone formation. J Cell Physiol. 2002;190(3):297–305.
Article
CAS
PubMed
Google Scholar
Fernandez MS, Moya A, Lopez L, Arias JL. Secretion pattern, ultrastructural localization and function of extracellular matrix molecules involved in eggshell formation. Matrix Biol. 2001;19(8):793–803.
Article
CAS
Google Scholar
Lavelin I, Meiri N, Einat M, Genina O, Pines M. Mechanical strain regulation of the chicken glypican-4 gene expression in the avian eggshell gland. Am J Physiol Regul Integr Comp Physiol. 2002;283(4):R853–61.
Article
PubMed
Google Scholar
Dwivedi PP, Grose RH, Filmus J, Hii CST, Xian CJ, Anderson PJ, Powell BC. Regulation of bone morphogenetic protein signalling and cranial osteogenesis by Gpc1 and Gpc3. Bone. 2013;55(2):367–76.
Article
CAS
PubMed
Google Scholar
Horvat-Gordon M, Yu F, Burns D, Leach RM. Ovocleidin (OC 116) is present in avian skeletal tissues. Poult Sci. 2008;87(8):1618–23.
Article
CAS
PubMed
Google Scholar
Fisher LW, Torchia DA, Fohr B, Young MF, Fedarko NS. Flexible structures of sibling proteins, bone sialoprotein, and osteopontin. Biochem Biophys Res Commun. 2001;280(2):460–5.
Article
CAS
PubMed
Google Scholar
Zhang YN, Zhang HJ, Wu SG, Wang J, Qi GH. Dietary manganese supplementation affects mammillary knobs of eggshell ultrastructure in laying hens. Poult Sci. 2018;97(4):1253–62.
Article
CAS
PubMed
Google Scholar
Du J, Xu G, Liu C, Zhang R. The role of phosphorylation and dephosphorylation of shell matrix proteins in shell formation: an in vivo and in vitro study. Crystengcomm. 2018;20(27):3905–16.
Article
CAS
Google Scholar
Zheng WM, Yoshimura Y, Tamura T. Effects of age and gonadal steroids on the localization of antigen-presenting cells, and T and B cells in the chicken oviduct. J Reprod Fertil. 1998;114(1):45–54.
Article
CAS
PubMed
Google Scholar
Barua A, Yoshimura Y. Immunolocalization of MHC-II+ cells in the ovary of immature, young laying and old laying hens Gallus domesticus. J Reprod Fertil. 1999;116(2):385–9.
Article
CAS
PubMed
Google Scholar
Barua A, Yoshimura Y. Effects of aging and sex steroids on the localization of T cell subsets in the ovary of chicken, Gallus domesticus. Gen Comp Endocrinol. 1999;114(1):28–35.
Article
CAS
PubMed
Google Scholar
Koch M, Camp S, Collen T, Avila D, Salomonsen J, Wallny H-J, Hateren AV, Hunt L, Jacob JP, Johnston F, Marston DA, Shaw I, Dunbar PR, Cerundolo V, Jones EY, Kaufman J. Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding. Immunity. 2007;27(6):885–99.
Article
CAS
PubMed
Google Scholar
Miller MM, Taylor RL. Brief review of the chicken major histocompatibility complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance. Poult Sci. 2016;95(2):375–92.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gromme M, Uytdehaag FGCM, Janssen H, Calafat J, Binnendijk RSV, Kenter MJH, Tulp A, Verwoerd D, Neefjes J. Recycling MHC Class I Molecules and endosomal peptide loading. Proc Natl Acad Sci U. S. A. 1999;96(18):10326–31.
Article
CAS
PubMed
PubMed Central
Google Scholar
Clark HL, Banks R, Jones L, Hornick TR, Higgins PA, Burant CJ, Canaday DH. Characterization of MHC-II antigen presentation by B cells and monocytes from older individuals. Clin Immunol. 2012;144(2):172–7.
Article
CAS
PubMed
Google Scholar
Wong C, Goldstein DR. Impact of aging on antigen presentation cell function of dendritic cells. Curr Opin Immunol. 2013;25(4):535–41.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis. 2002;2(11):659–66.
Article
PubMed
Google Scholar
Elhamouly M, Nii T, Isobe N, Yoshimura Y. Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens. Cytokine. 2018;111:303–8.
Article
CAS
PubMed
Google Scholar
Tanikawa N, Ohtsu A, Kawahara-Miki R, Kimura K, Matsuyama S, Iwata H, Kuwayama T, Shirasuna K. Age-associated mRNA expression changes in bovine endometrial cells in vitro. Reprod Biol Endocrinol. 2017;15(1):63.
Article
PubMed
PubMed Central
CAS
Google Scholar
Man AL, Bertelli E, Rentini S, Regoli M, Briars G, Marini M, Watson AJM, Nicoletti C. Age-associated modifications of intestinal permeability and innate immunity in human small intestine. Clin Sci. 2015;129(7):515–27.
Article
CAS
Google Scholar
Yarbrough VL, Winkle S, Herbst-Kralovetz MM. Antimicrobial peptides in the female reproductive tract: a critical component of the mucosal immune barrier with physiological and clinical implications. Hum Reprod Update. 2015;21(3):353–77.
Article
CAS
PubMed
Google Scholar
Elhamouly M, Nii T, Isobe N, Yoshimura Y. Age-related modulation of the isthmic and uterine mucosal innate immune defense system in laying hens. Poult Sci. 2019;98(7):3022–8.
Article
CAS
PubMed
Google Scholar
Sun C, Xu G, Yang N. Differential label-free quantitative proteomic analysis of avian eggshell matrix and uterine fluid proteins associated with eggshell mechanical property. Proteomics. 2013;13(23–24):3523–36.
Article
CAS
PubMed
Google Scholar
Takahiro N, Naoki I, Yukinori Y. Effects of interleukin-1 beta and-6 on the expression of ion transporters involved in eggshell mineralization in cultured hen uterine mucosal tissue. J Poult Sci. 2018;55(2):142–9.
Article
CAS
Google Scholar
Nii T, Isobe N, Yoshimura Y. Effects of avian infectious bronchitis virus antigen on eggshell formation and immunoreaction in hen oviduct. Theriogenology. 2014;81(8):1129–38.
Article
CAS
PubMed
Google Scholar
Qi X, Tan D, Wu C, Tang C, Li T, Han X, Wang J, Liu C, Li R, Wang J. Deterioration of eggshell quality in laying hens experimentally infected with H9N2 avian influenza virus. Vet Res. 2016;47(1):35.
Article
PubMed
PubMed Central
CAS
Google Scholar
Taylor KR, Gallo RL. Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation. FASEB J. 2006;20(1):9–22.
Article
CAS
PubMed
Google Scholar
Gongruttananun N. Induced molt using cassava meal. 2. Effects on eggshell quality, ultrastructure, and pore density in late-phase laying hens. Poult Sci. 2018;97(3):1050–8.
Article
CAS
PubMed
Google Scholar
Levy E, Beaulieu JF, Delvin E, Seidman E, Yotov W, Basque JR, Ménard D. Human crypt intestinal epithelial cells are capable of lipid production, apolipoprotein synthesis, and lipoprotein assembly. J Lipid Res. 2000;41(1):12–22.
CAS
PubMed
Google Scholar
Mabe I, Rapp C, Bain M, Nys Y. Supplementation of a corn-soybean meal diet with manganese, copper, and zinc from organic or inorganic sources improves eggshell quality in aged laying hens. Poult Sci. 2003;82(12):1903–13.
Article
CAS
PubMed
Google Scholar
Bain MM. Eggshell strength: a mechanical/ultrastructural evaluation. Ph.D. Thesis. Glasgow: University of Glasgow; 1990.
Google Scholar
Bain MM. Eggshell strength: a relationship between the mechanism of failure and the ultrastructural organisation of the mammillary layer. Br Poult Sci. 1992;33(2):303–19.
Article
Google Scholar
Ahmed AM, Rodriguez-Navarro AB, Vidal ML, Gautron J, García-Ruiz JM, Nys Y. Changes in eggshell mechanical properties, crystallographic texture and in matrix proteins induced by moult in hens.[J]. Br Poult Sci. 2005;46(3):268–79.
Article
CAS
PubMed
Google Scholar
Young MD, Wakefield MJ, Smyth GK, Oshlack A. Gene ontology analysis for RNA-seq: accounting for selection bias. Genome Biol. 2010;11(2):R14.
Article
PubMed
PubMed Central
CAS
Google Scholar
Mao X, Tao C, Olyarchuk JG, Wei L. Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary. Bioinformatics. 2005;21(19):3787–93.
Article
CAS
PubMed
Google Scholar
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCt method. Methods. 2001;25(4):402–8.
Article
CAS
Google Scholar