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Volume 10 Supplement 3
Edited by Shoba Ranganathan, Frank Eisenhaber, Joo Chuan Tong and Tin Wee Tan
Asia Pacific Bioinformatics Network (APBioNet) Eighth International Conference on Bioinformatics (InCoB2009). Go to conference site.
Singapore
7-11 September 2009
Introduction
The 2009 annual conference of the Asia Pacific Bioinformatics Network (APBioNet), Asia's oldest bioinformatics organisation dating back to 1998, was organized as the 8th International Conference on Bioinformatics...
BMC Genomics 2009 10(Suppl 3):S1
Published on: 3 December 2009
Proceedings
Next-generation DNA sequencing technologies generate tens of millions of sequencing reads in one run. These technologies are now widely used in biology research such as in genome-wide identification of polymor...
BMC Genomics 2009 10(Suppl 3):S2
Published on: 3 December 2009
Proceedings
Oligonucleotide design is known as a time-consuming work in bioinformatics. In order to accelerate and be efficient the oligonucleotide design process, one of widely used approach is the prescreening unreliabl...
BMC Genomics 2009 10(Suppl 3):S3
Published on: 3 December 2009
Proceedings
Polymerase chain reaction (PCR) is very useful in many areas of molecular biology research. It is commonly observed that PCR success is critically dependent on design of an effective primer pair. Current tools...
BMC Genomics 2009 10(Suppl 3):S4
Published on: 3 December 2009
Proceedings
Activation of PPARs has been reported to inhibit the proliferation of malignant cells from different lineages. They are involved in transcription regulation of genes upon activation by a ligand. The binding of...
BMC Genomics 2009 10(Suppl 3):S5
Published on: 3 December 2009
Proceedings
Caspases belong to a class of cysteine proteases which function as critical effectors in cellular processes such as apoptosis and inflammation by cleaving substrates immediately after unique tetrapeptide sites...
BMC Genomics 2009 10(Suppl 3):S6
Published on: 3 December 2009
Proceedings
Insertional mutagenesis is an effective method for functional genomic studies in various organisms. It can rapidly generate easily tractable mutations. A large-scale insertional mutagenesis with the piggyBac (PB)...
BMC Genomics 2009 10(Suppl 3):S7
Published on: 3 December 2009
Proceedings
DNA barcoding provides a rapid, accurate, and standardized method for species-level identification using short DNA sequences. Such a standardized identification method is useful for mapping all the species on ...
BMC Genomics 2009 10(Suppl 3):S8
Published on: 3 December 2009
Proceedings
DNA triplexes can naturally occur, co-localize and interact with many other regulatory DNA elements (e.g. G-quadruplex (G4) DNA motifs), specific DNA-binding proteins (e.g. transcription factors (TFs)), and mi...
BMC Genomics 2009 10(Suppl 3):S9
Published on: 3 December 2009
Proceedings
The characterisation, or binning, of metagenome fragments is an important first step to further downstream analysis of microbial consortia. Here, we propose a one-dimensional signature, OFDEG, derived from the...
BMC Genomics 2009 10(Suppl 3):S10
Published on: 3 December 2009
Proceedings
Alternative splicing (AS) is a primary mechanism of functional regulation in the human genome, with 60% to 80% of human genes being alternatively spliced. As part of the bovine genome annotation team, we have ...
BMC Genomics 2009 10(Suppl 3):S11
Published on: 3 December 2009
Proceedings
Mitochondrial sequence variation provides critical information for studying human evolution and variation. Mitochondrial DNA provides information on the origin of humans, and plays a substantial role in forens...
BMC Genomics 2009 10(Suppl 3):S12
Published on: 3 December 2009
Proceedings
Next-generation sequencing technologies provide exciting avenues for studies of transcriptomics and population genomics. There is an increasing need to conduct spliced and unspliced alignments of short transcr...
BMC Genomics 2009 10(Suppl 3):S13
Published on: 3 December 2009
Proceedings
Grouping genes into clusters on the basis of similarity between their expression profiles has been the main approach to predict functional modules, from which important inference or further investigation decis...
BMC Genomics 2009 10(Suppl 3):S14
Published on: 3 December 2009
Proceedings
Gene expression similarity measuring methods were developed and applied to search rapidly growing public microarray databases. However, current expression similarity measuring methods need to be improved to ac...
BMC Genomics 2009 10(Suppl 3):S15
Published on: 3 December 2009
Proceedings
It has been a long-standing biological challenge to understand the molecular regulatory mechanisms behind mammalian ageing. Harnessing the availability of many ageing microarray datasets, a number of studies h...
BMC Genomics 2009 10(Suppl 3):S16
Published on: 3 December 2009
Proceedings
The reconstruction of gene regulatory networks from high-throughput "omics" data has become a major goal in the modelling of living systems. Numerous approaches have been proposed, most of which attempt only "...
BMC Genomics 2009 10(Suppl 3):S17
Published on: 3 December 2009
Proceedings
Pseudomonas putida KT2440 (P. putida KT2440) is a highly versatile saprophytic soil bacterium. It is a certified bio-safety host for transferring foreign genes. Therefore, the bacterium is used as a model organis...
BMC Genomics 2009 10(Suppl 3):S18
Published on: 3 December 2009
Proceedings
The PolyGalacturonase-Inhibiting Proteins (PGIP) of plant cell wall limit the invasion of phytopathogenic organisms by interacting with the enzyme PolyGalacturonase (PG) they secrete to degrade pectin present ...
BMC Genomics 2009 10(Suppl 3):S19
Published on: 3 December 2009
Proceedings
Mitochondria play a vital role in the energy production and apoptotic process of eukaryotic cells. Proteins in the mitochondria are encoded by nuclear and mitochondrial genes. Owing to a large increase in the ...
BMC Genomics 2009 10(Suppl 3):S20
Published on: 3 December 2009
The editors of BMC Genomics support initiatives that expedite the peer review process and are happy to consider manuscripts that have been reviewed in Peerage of Science. Please indicate in your cover letter if this applies to your manuscript.
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