Citation Impact
3.594 - 2-year Impact Factor
4.093 - 5-year Impact Factor
1.140 - Source Normalized Impact per Paper (SNIP)
1.629 - SCImago Journal Rank (SJR)
Usage
5,243,550 Downloads
5590 Altmetric Mentions
Volume 10 Supplement 3
Edited by Shoba Ranganathan, Frank Eisenhaber, Joo Chuan Tong and Tin Wee Tan
Asia Pacific Bioinformatics Network (APBioNet) Eighth International Conference on Bioinformatics (InCoB2009). Go to conference site.
Singapore7-11 September 2009
The 2009 annual conference of the Asia Pacific Bioinformatics Network (APBioNet), Asia's oldest bioinformatics organisation dating back to 1998, was organized as the 8th International Conference on Bioinformatics...
Citation: BMC Genomics 2009 10(Suppl 3):S1
Next-generation DNA sequencing technologies generate tens of millions of sequencing reads in one run. These technologies are now widely used in biology research such as in genome-wide identification of polymor...
Citation: BMC Genomics 2009 10(Suppl 3):S2
Oligonucleotide design is known as a time-consuming work in bioinformatics. In order to accelerate and be efficient the oligonucleotide design process, one of widely used approach is the prescreening unreliabl...
Citation: BMC Genomics 2009 10(Suppl 3):S3
Polymerase chain reaction (PCR) is very useful in many areas of molecular biology research. It is commonly observed that PCR success is critically dependent on design of an effective primer pair. Current tools...
Citation: BMC Genomics 2009 10(Suppl 3):S4
Activation of PPARs has been reported to inhibit the proliferation of malignant cells from different lineages. They are involved in transcription regulation of genes upon activation by a ligand. The binding of...
Citation: BMC Genomics 2009 10(Suppl 3):S5
Caspases belong to a class of cysteine proteases which function as critical effectors in cellular processes such as apoptosis and inflammation by cleaving substrates immediately after unique tetrapeptide sites...
Citation: BMC Genomics 2009 10(Suppl 3):S6
Insertional mutagenesis is an effective method for functional genomic studies in various organisms. It can rapidly generate easily tractable mutations. A large-scale insertional mutagenesis with the piggyBac (PB)...
Citation: BMC Genomics 2009 10(Suppl 3):S7
DNA barcoding provides a rapid, accurate, and standardized method for species-level identification using short DNA sequences. Such a standardized identification method is useful for mapping all the species on ...
Citation: BMC Genomics 2009 10(Suppl 3):S8
DNA triplexes can naturally occur, co-localize and interact with many other regulatory DNA elements (e.g. G-quadruplex (G4) DNA motifs), specific DNA-binding proteins (e.g. transcription factors (TFs)), and mi...
Citation: BMC Genomics 2009 10(Suppl 3):S9
The characterisation, or binning, of metagenome fragments is an important first step to further downstream analysis of microbial consortia. Here, we propose a one-dimensional signature, OFDEG, derived from the...
Citation: BMC Genomics 2009 10(Suppl 3):S10
Alternative splicing (AS) is a primary mechanism of functional regulation in the human genome, with 60% to 80% of human genes being alternatively spliced. As part of the bovine genome annotation team, we have ...
Citation: BMC Genomics 2009 10(Suppl 3):S11
Mitochondrial sequence variation provides critical information for studying human evolution and variation. Mitochondrial DNA provides information on the origin of humans, and plays a substantial role in forens...
Citation: BMC Genomics 2009 10(Suppl 3):S12
Next-generation sequencing technologies provide exciting avenues for studies of transcriptomics and population genomics. There is an increasing need to conduct spliced and unspliced alignments of short transcr...
Citation: BMC Genomics 2009 10(Suppl 3):S13
Grouping genes into clusters on the basis of similarity between their expression profiles has been the main approach to predict functional modules, from which important inference or further investigation decis...
Citation: BMC Genomics 2009 10(Suppl 3):S14
Gene expression similarity measuring methods were developed and applied to search rapidly growing public microarray databases. However, current expression similarity measuring methods need to be improved to ac...
Citation: BMC Genomics 2009 10(Suppl 3):S15
It has been a long-standing biological challenge to understand the molecular regulatory mechanisms behind mammalian ageing. Harnessing the availability of many ageing microarray datasets, a number of studies h...
Citation: BMC Genomics 2009 10(Suppl 3):S16
The reconstruction of gene regulatory networks from high-throughput "omics" data has become a major goal in the modelling of living systems. Numerous approaches have been proposed, most of which attempt only "...
Citation: BMC Genomics 2009 10(Suppl 3):S17
Pseudomonas putida KT2440 (P. putida KT2440) is a highly versatile saprophytic soil bacterium. It is a certified bio-safety host for transferring foreign genes. Therefore, the bacterium is used as a model organis...
Citation: BMC Genomics 2009 10(Suppl 3):S18
The PolyGalacturonase-Inhibiting Proteins (PGIP) of plant cell wall limit the invasion of phytopathogenic organisms by interacting with the enzyme PolyGalacturonase (PG) they secrete to degrade pectin present ...
Citation: BMC Genomics 2009 10(Suppl 3):S19
Mitochondria play a vital role in the energy production and apoptotic process of eukaryotic cells. Proteins in the mitochondria are encoded by nuclear and mitochondrial genes. Owing to a large increase in the ...
Citation: BMC Genomics 2009 10(Suppl 3):S20
In this paper, we introduce a novel inter-range interaction integrated approach for protein domain boundary prediction. It involves (1) the design of modular kernel algorithm, which is able to effectively expl...
Citation: BMC Genomics 2009 10(Suppl 3):S21
Proteins are dynamic macromolecules which may undergo conformational transitions upon changes in environment. As it has been observed in laboratories that protein flexibility is correlated to essential biologi...
Citation: BMC Genomics 2009 10(Suppl 3):S22
Protein-DNA interactions are essential for fundamental biological activities including DNA transcription, replication, packaging, repair and rearrangement. Proteins interacting with DNA can be classified into ...
Citation: BMC Genomics 2009 10(Suppl 3):S23
It is known that the highly pathogenic avian influenza A virus H5N1 binds strongly and with high specificity to the avian-type receptor by its hemagglutinin surface protein. This specificity is normally a barr...
Citation: BMC Genomics 2009 10(Suppl 3):S24
Most phylogenetic studies using current methods have focused on primary DNA sequence information. However, RNA secondary structures are particularly useful in systematics because they include characteristics t...
Citation: BMC Genomics 2009 10(Suppl 3):S25
The steady-state behaviour of gene regulatory networks (GRNs) can provide crucial evidence for detecting disease-causing genes. However, monitoring the dynamics of GRNs is particularly difficult because biolog...
Citation: BMC Genomics 2009 10(Suppl 3):S26
Eukaryotic genomes are packaged into chromatin, a compact structure containing fundamental repeating units, the nucleosomes. The mobility of nucleosomes plays important roles in many DNA-related processes by r...
Citation: BMC Genomics 2009 10(Suppl 3):S27
Time delays are often found in gene regulation though most techniques of building gene regulatory networks are not capable of capturing such phenomena. Here we look at the delays in the DNA repair system of Mycob...
Citation: BMC Genomics 2009 10(Suppl 3):S28
Gene regulation is a key mechanism in higher eukaryotic cellular processes. One of the major challenges in gene regulation studies is to identify regulators affecting the expression of their target genes in sp...
Citation: BMC Genomics 2009 10(Suppl 3):S29
Human immunodeficiency virus-1 (HIV-1) has a minimal genome of only 9 genes, which encode 15 proteins. HIV-1 thus depends on the human host for virtually every aspect of its life cycle. The universal language ...
Citation: BMC Genomics 2009 10(Suppl 3):S30
Rate-limiting enzymes, because of their relatively low velocity, are believed to influence metabolic flux in pathways. To investigate their regulatory role in metabolic networks, we look at the global organiza...
Citation: BMC Genomics 2009 10(Suppl 3):S31
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, clinically characterized by impaired motor function. Since the etiology of PD is diverse and complex, many researchers have creat...
Citation: BMC Genomics 2009 10(Suppl 3):S32
Lysosomal α-mannosidase is an enzyme that acts to degrade N-linked oligosaccharides and hence plays an important role in mannose metabolism in humans and other mammalian species, especially livestock. Mutation...
Citation: BMC Genomics 2009 10(Suppl 3):S33
Medical and biological data are commonly with small sample size, missing values, and most importantly, imbalanced class distribution. In this study we propose a particle swarm based hybrid system for remedying...
Citation: BMC Genomics 2009 10(Suppl 3):S34
A disease-causing mutation refers to a heritable genetic change that is associated with a specific phenotype (disease). The detection of a mutation from a patient's sample is critical for the diagnosis, treatm...
Citation: BMC Genomics 2009 10(Suppl 3):S35
The development of high throughput experimental technologies have given rise to the "-omics" era where terabyte-scale datasets for systems-level measurements of various cellular and molecular phenomena pose co...
Citation: BMC Genomics 2009 10(Suppl 3):S36
Citation Impact
3.594 - 2-year Impact Factor
4.093 - 5-year Impact Factor
1.140 - Source Normalized Impact per Paper (SNIP)
1.629 - SCImago Journal Rank (SJR)
Usage
5,243,550 Downloads
5590 Altmetric Mentions
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