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Volume 12 Supplement 5

The 2010 International Conference on Bioinformatics and Computational Biology (BIOCOMP 2010): Genomics

Research

Edited by Ke Zhang, Mehdi Pirooznia, Hamid R Arabnia

BIOCOMP 2010. The 2010 International Conference on Bioinformatics and Computational Biology.

Las Vegas, NV, USA12-15 July 2010

  1. This is an editorial report of the supplement to BMC Genomics that includes 15 papers selected from the BIOCOMP'10 - The 2010 International Conference on Bioinformatics & Computational Biology as well as other...

    Authors: Ke Zhang, Mehdi Pirooznia, Hamid R Arabnia, Jack Y Yang, Liangjiang Wang, Zuojie Luo and Youping Deng
    Citation: BMC Genomics 2011 12(Suppl 5):I1
    Content type: Introduction Published on:

  2. Microarray data have a high dimension of variables and a small sample size. In microarray data analyses, two important issues are how to choose genes, which provide reliable and good prediction for disease sta...

    Authors: Qingzhong Liu, Andrew H Sung, Zhongxue Chen, Jianzhong Liu, Lei Chen, Mengyu Qiao, Zhaohui Wang, Xudong Huang and Youping Deng
    Citation: BMC Genomics 2011 12(Suppl 5):S1
    Content type: Research article Published on:

  4. Microarray data have been used for gene signature selection to predict clinical outcomes. Many studies have attempted to identify factors that affect models' performance with only little success. Fine-tuning o...

    Authors: Chen Zhao, Leming Shi, Weida Tong, John D Shaughnessy Jr, André Oberthuer, Lajos Pusztai, Youping Deng, W Fraser Symmans and Tieliu Shi
    Citation: BMC Genomics 2011 12(Suppl 5):S3
    Content type: Research article Published on:

  6. Panax notoginseng (Burk) F.H. Chen is important medicinal plant of the Araliacease family. Triterpene saponins are the bioactive constituents in P. notoginseng. However, available genomic information regarding th...

    Authors: Hongmei Luo, Chao Sun, Yongzhen Sun, Qiong Wu, Ying Li, Jingyuan Song, Yunyun Niu, Xianglin Cheng, Hongxi Xu, Chuyuan Li, Juyan Liu, André Steinmetz and Shilin Chen
    Citation: BMC Genomics 2011 12(Suppl 5):S5
    Content type: Research article Published on:

  7. The use of gene signatures can potentially be of considerable value in the field of clinical diagnosis. However, gene signatures defined with different methods can be quite various even when applied the same d...

    Authors: Chang Chang, Junwei Wang, Chen Zhao, Jennifer Fostel, Weida Tong, Pierre R Bushel, Youping Deng, Lajos Pusztai, W Fraser Symmans and Tieliu Shi
    Citation: BMC Genomics 2011 12(Suppl 5):S6
    Content type: Research article Published on:

  8. In microarray experiments with small sample sizes, it is a challenge to estimate p-values accurately and decide cutoff p-values for gene selection appropriately. Although permutation-based methods have proved ...

    Authors: Zhongxue Chen, Qingzhong Liu, Monnie McGee, Megan Kong, Xudong Huang, Youping Deng and Richard H Scheuermann
    Citation: BMC Genomics 2011 12(Suppl 5):S7
    Content type: Research article Published on:

  9. RNA-binding proteins (RBPs) play diverse roles in eukaryotic RNA processing. Despite their pervasive functions in coding and noncoding RNA biogenesis and regulation, elucidating the sequence specificities that...

    Authors: Xin Wang, Liran Juan, Junjie Lv, Kejun Wang, Jeremy R Sanford and Yunlong Liu
    Citation: BMC Genomics 2011 12(Suppl 5):S8
    Content type: Research article Published on:

  11. The recent advancement in array CGH (aCGH) research has significantly improved tumor identification using DNA copy number data. A number of unsupervised learning methods have been proposed for clustering aCGH ...

    Authors: Ke Zhang, Yi Yang, Viswanath Devanarayan, Linglin Xie, Youping Deng and Sens Donald
    Citation: BMC Genomics 2011 12(Suppl 5):S10
    Content type: Research article Published on:

  12. Studies of toxicity and unintended side effects can lead to improved drug safety and efficacy. One promising form of study comes from molecular systems biology in the form of "systems pharmacology". Systems ph...

    Authors: Liang-Chin Huang, Xiaogang Wu and Jake Y Chen
    Citation: BMC Genomics 2011 12(Suppl 5):S11
    Content type: Research article Published on:

  13. Along with obesity, physical inactivity, and family history of metabolic disorders, African American ethnicity is a risk factor for type 2 diabetes (T2D) in the United States. However, little is known about th...

    Authors: Jinghe Mao, Junmei Ai, Xinchun Zhou, Ming Shenwu, Manuel Ong Jr, Marketta Blue, Jasmine T Washington, Xiaonan Wang and Youping Deng
    Citation: BMC Genomics 2011 12(Suppl 5):S12
    Content type: Research article Published on:

  14. Dynamic Bayesian Network (DBN) is an approach widely used for reconstruction of gene regulatory networks from time-series microarray data. Its performance in network reconstruction depends on a structure learn...

    Authors: Haoni Li, Nan Wang, Ping Gong, Edward J Perkins and Chaoyang Zhang
    Citation: BMC Genomics 2011 12(Suppl 5):S13
    Content type: Research article Published on:

  15. Speckles in ultrasound imaging affect image quality and can make the post-processing difficult. Speckle reduction technologies have been employed for removing speckles for some time. One of the effective speck...

    Authors: Xiaoming Liu, Jun Liu, Xin Xu, Lei Chun, Jinshan Tang and Youping Deng
    Citation: BMC Genomics 2011 12(Suppl 5):S14
    Content type: Research article Published on:

  16. DNA methylation in the 5' promoter regions of genes and microRNA (miRNA) regulation at the 3' untranslated regions (UTRs) are two major epigenetic regulation mechanisms in most eukaryotes. Both DNA methylation...

    Authors: Zhixi Su, Junfeng Xia and Zhongming Zhao
    Citation: BMC Genomics 2011 12(Suppl 5):S15
    Content type: Research article Published on:
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BMC Genomics

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