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  1. The CRISPR/Cas9 system is a prokaryotic immune system that infers resistance to foreign genetic material and is a sort of 'adaptive immunity'. It has been adapted to enable high throughput genome editing and h...

    Authors: Isabel Brocal, Richard J. White, Christopher M. Dooley, Samantha N. Carruthers, Richard Clark, Amanda Hall, Elisabeth M. Busch-Nentwich, Derek L. Stemple and Ross N. W. Kettleborough
    Citation: BMC Genomics 2016 17:259
    Content type: Methodology article Published on:

  2. Barley leaf stripe disease, caused by the fungus Pyrenophora graminea (Pg), is a worldwide crop disease that results in significant loss of barley yield. The purpose of the present work was to use transcriptomic ...

    Authors: Ahmed Ghannam, Houda Alek, Sanaa Doumani, Doureid Mansour and Mohamad I. E. Arabi
    Citation: BMC Genomics 2016 17:256
    Content type: Research article Published on:

  4. In a world of chemical cues, smell and taste are essential senses for survival. Here we focused on Heliconius, a diverse group of butterflies that exhibit variation in pre- and post-zygotic isolation and chemical...

    Authors: Bas van Schooten, Chris D. Jiggins, Adriana D. Briscoe and Riccardo Papa
    Citation: BMC Genomics 2016 17:254
    Content type: Research article Published on:

  5. Biofilm formation is an important survival strategy of Salmonella in all environments. By mutant screening, we showed a knock-out mutant of fabR, encoding a repressor of unsaturated fatty acid biosynthesis (UFA),...

    Authors: Kim Hermans, Stefanie Roberfroid, Inge M. Thijs, Gwendoline Kint, David De Coster, Kathleen Marchal, Jos Vanderleyden, Sigrid C. J. De Keersmaecker and Hans P. Steenackers
    Citation: BMC Genomics 2016 17:253
    Content type: Research article Published on:

  7. The MYB family is one of the most abundant transcription factor families in plants. MYB proteins are involved in plant development, abiotic stress tolerance, hormone signal transduction and disease resistance....

    Authors: Xianjun Peng, Hui Liu, Dan Wang and Shihua Shen
    Citation: BMC Genomics 2016 17:251
    Content type: Research article Published on:

  8. Genes in the sex determination pathway are important regulators of sexually dimorphic animal traits, including the elaborate and exaggerated male ornaments and weapons of sexual selection. In this study, we id...

    Authors: Hiroki Gotoh, Robert A. Zinna, Ian Warren, Michael DeNieu, Teruyuki Niimi, Ian Dworkin, Douglas J. Emlen, Toru Miura and Laura C. Lavine
    Citation: BMC Genomics 2016 17:250
    Content type: Research article Published on:

  9. Trichophyton rubrum is a cosmopolitan filamentous fungus that can infect human keratinized tissue (skin, nails and, rarely, hair) and is the major agent of all chronic and recurrent de...

    Authors: Tamires Aparecida Bitencourt, Claudia Macedo, Matheus Eloy Franco, Amanda Freire Assis, Tatiana Takahasi Komoto, Eliana Guedes Stehling, Rene Oliveira Beleboni, Iran Malavazi, Mozart Marins and Ana Lúcia Fachin
    Citation: BMC Genomics 2016 17:249
    Content type: Research article Published on:

  10. Vascular wilt caused by Fusarium oxysporum is the most important disease in cape gooseberry (Physalis peruviana L.) in Colombia. The development of resistant cultivars is considered one of the most cost-effective...

    Authors: Jaime A. Osorio-Guarín, Felix E. Enciso-Rodríguez, Carolina González, Noé Fernández-Pozo, Lukas A. Mueller and Luz Stella Barrero
    Citation: BMC Genomics 2016 17:248
    Content type: Research article Published on:

  11. Hepatitis C virus (HCV) is a rapidly evolving RNA virus that has been classified into seven genotypes. All HCV genotypes cause chronic hepatitis, which ultimately leads to liver diseases such as cirrhosis. The...

    Authors: Rowena A. Bull, Auda A. Eltahla, Chaturaka Rodrigo, Sylvie M. Koekkoek, Melanie Walker, Mehdi R. Pirozyan, Brigid Betz-Stablein, Armin Toepfer, Melissa Laird, Steve Oh, Cheryl Heiner, Lisa Maher, Janke Schinkel, Andrew R. Lloyd and Fabio Luciani
    Citation: BMC Genomics 2016 17:247
    Content type: Methodology article Published on:

  12. Protein Phosphatase 1 (PP1) is an enzyme essential to cell viability in the malaria parasite Plasmodium falciparum (Pf). The activity of PP1 is regulated by the binding of regulatory subunits, of which there are ...

    Authors: Thomas Hollin, Caroline De Witte, Astrid Lenne, Christine Pierrot and Jamal Khalife
    Citation: BMC Genomics 2016 17:246
    Content type: Research article Published on:

  13. Sugar beet (Beta vulgaris) is a crop cultivated for its high content in sugar, but it is vulnerable to many soil-borne pathogens. One of them is the basidiomycete Rhizoctonia solani. This fungal species has a com...

    Authors: Daniel Wibberg, Louise Andersson, Georgios Tzelepis, Oliver Rupp, Jochen Blom, Lukas Jelonek, Alfred Pühler, Johan Fogelqvist, Mark Varrelmann, Andreas Schlüter and Christina Dixelius
    Citation: BMC Genomics 2016 17:245
    Content type: Research article Published on:

  14. Compensatory growth (CG) is an accelerated growth phenomenon observed in animals upon re-alimentation following a period of dietary restriction. It is typically utilised in livestock systems to reduce feed cos...

    Authors: Kate Keogh, David A. Kenny, Paul Cormican, Alan K. Kelly and Sinead M. Waters
    Citation: BMC Genomics 2016 17:244
    Content type: Research article Published on:

  15. Recent advances in genomics indicate functional significance of a majority of genome sequences and their long range interactions. As a detailed examination of genome organization and function requires very hig...

    Authors: Guillaume Martin, Franc-Christophe Baurens, Gaëtan Droc, Mathieu Rouard, Alberto Cenci, Andrzej Kilian, Alex Hastie, Jaroslav Doležel, Jean-Marc Aury, Adriana Alberti, Françoise Carreel and Angélique D’Hont
    Citation: BMC Genomics 2016 17:243
    Content type: Methodology article Published on:

  16. Rice is a major staple food crop in the world. Over 80 % of rice cultivation area is under indica rice. Currently, genomic resources are lacking for indica as compared to japonica rice. In this study, we generate...

    Authors: H. B. Mahesh, Meghana Deepak Shirke, Siddarth Singh, Anantharamanan Rajamani, Shailaja Hittalmani, Guo-Liang Wang and Malali Gowda
    Citation: BMC Genomics 2016 17:242
    Content type: Research article Published on:

  17. Hard ticks (family Ixodidae) are obligatory hematophagous ectoparasites of worldwide medical and veterinary importance. The haploid genomes of multiple species of ixodid ticks exceed 1 Gbp, prompting questions...

    Authors: Janice P. Van Zee, Jessica A. Schlueter, Shannon Schlueter, Philip Dixon, Carlos A. Brito Sierra and Catherine A. Hill
    Citation: BMC Genomics 2016 17:241
    Content type: Research article Published on:

  18. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a central enzyme in glycolysi, we performed genome-wide identification of GAPDH genes in wheat and analyzed their structural characteristics and expression patt...

    Authors: Lingfeng Zeng, Rong Deng, Ziping Guo, Shushen Yang and Xiping Deng
    Citation: BMC Genomics 2016 17:240
    Content type: Research article Published on:

  19. Common bean (Phaseolus vulgaris) is an important grain legume and there has been a recent resurgence in interest in its relative, tepary bean (P. acutifolius), owing to this species’ ability to better withstand a...

    Authors: Neha Gujaria-Verma, Larissa Ramsay, Andrew G. Sharpe, Lacey-Anne Sanderson, Daniel G. Debouck, Bunyamin Tar’an and Kirstin E. Bett
    Citation: BMC Genomics 2016 17:239
    Content type: Research article Published on:

  20. Stripe rust (Puccinia striiformis f. sp. tritici; Pst) and powdery mildew (Blumeria graminis f. sp. tritici; Bgt) are important diseases of wheat (Triticum aestivum) worldwide. Increasingly evidences suggest that...

    Authors: Hong Zhang, Weiguo Hu, Jilei Hao, Shikai Lv, Changyou Wang, Wei Tong, Yajuan Wang, Yanzhen Wang, Xinlun Liu and Wanquan Ji
    Citation: BMC Genomics 2016 17:238
    Content type: Research article Published on:

  21. Surface-associated communities of bacteria, known as biofilms, play a critical role in the persistence and dissemination of bacteria in various environments. Biofilm development is a sequential dynamic process...

    Authors: Cyril Guilhen, Nicolas Charbonnel, Nicolas Parisot, Nathalie Gueguen, Agnès Iltis, Christiane Forestier and Damien Balestrino
    Citation: BMC Genomics 2016 17:237
    Content type: Research article Published on:

  22. The combination of bulk segregant analysis (BSA) and next generation sequencing (NGS), also known as mapping by sequencing (MBS), has been shown to significantly accelerate the identification of causal mutatio...

    Authors: David Ries, Daniela Holtgräwe, Prisca Viehöver and Bernd Weisshaar
    Citation: BMC Genomics 2016 17:236
    Content type: Methodology article Published on:

  23. Nelore is the major beef cattle breed in Brazil with more than 130 million heads. Genome-wide association studies (GWAS) are often used to associate markers and genomic regions to growth and meat quality trait...

    Authors: Maurício A. Mudadu, Laercio R. Porto-Neto, Fabiana B. Mokry, Polyana C. Tizioto, Priscila S. N. Oliveira, Rymer R. Tullio, Renata T. Nassu, Simone C. M. Niciura, Patrícia Tholon, Maurício M. Alencar, Roberto H. Higa, Antônio N. Rosa, Gélson L. D. Feijó, André L. J. Ferraz, Luiz O. C. Silva, Sérgio R. Medeiros…
    Citation: BMC Genomics 2016 17:235
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2016 17:492

  24. The basidiomycete Rigidoporus microporus is a fungus that causes the white rot disease of the tropical rubber tree, Hevea brasiliensis, the major source of commercial natural rubber. Besides its lifestyle as a pa...

    Authors: Abbot O. Oghenekaro, Tommaso Raffaello, Andriy Kovalchuk and Fred O. Asiegbu
    Citation: BMC Genomics 2016 17:234
    Content type: Research article Published on:

  25. Experimental evolution studies, coupled with whole genome resequencing and advances in bioinformatics, have become a powerful tool for exploring how populations respond to selection at the genome-wide level, c...

    Authors: Lin Kang, Dau Dayal Aggarwal, Eugenia Rashkovetsky, Abraham B. Korol and Pawel Michalak
    Citation: BMC Genomics 2016 17:233
    Content type: Research article Published on:

  26. Network medicine is a promising new discipline that combines systems biology approaches and network science to understand the complexity of pathological phenotypes. Given the growing availability of personaliz...

    Authors: Armando Reyes-Palomares, Aníbal Bueno, Rocío Rodríguez-López, Miguel Ángel Medina, Francisca Sánchez-Jiménez, Manuel Corpas and Juan A. G. Ranea
    Citation: BMC Genomics 2016 17:232
    Content type: Research article Published on:

  27. The neonatal murine heart is able to regenerate after severe injury; this capacity however, quickly diminishes and it is lost within the first week of life. DNA methylation is an epigenetic mechanism which pla...

    Authors: Bartosz Górnikiewicz, Anna Ronowicz, Michał Krzemiński and Paweł Sachadyn
    Citation: BMC Genomics 2016 17:231
    Content type: Research article Published on:

  28. In woody perennial plants, including deciduous fruit trees, such as pear, endodormancy is a strategy for surviving the cold winter. A better understanding of the mechanism underlying the endodormancy phase tra...

    Authors: Songling Bai, Takanori Saito, Akiko Ito, Pham Anh Tuan, Ying Xu, Yuanwen Teng and Takaya Moriguchi
    Citation: BMC Genomics 2016 17:230
    Content type: Research article Published on:

  29. Effector proteins are translocated into host cells by plant-pathogens to undermine pattern-triggered immunity (PTI), the plant response to microbe-associated molecular patterns that interferes with the infecti...

    Authors: Jay N. Worley, Marina A. Pombo, Yi Zheng, Diane M. Dunham, Christopher R. Myers, Zhangjun Fei and Gregory B. Martin
    Citation: BMC Genomics 2016 17:229
    Content type: Research article Published on:

  30. Inference of gene regulation from expression data may help to unravel regulatory mechanisms involved in complex diseases or in the action of specific drugs. A challenging task for many researchers working in t...

    Authors: Angela Grassi, Barbara Di Camillo, Francesco Ciccarese, Valentina Agnusdei, Paola Zanovello, Alberto Amadori, Lorenzo Finesso, Stefano Indraccolo and Gianna Maria Toffolo
    Citation: BMC Genomics 2016 17:228
    Content type: Research article Published on:

  31. Chlamydomonas reinhardtii is the model organism that serves as a reference for studies in algal genomics and physiology. It is of special interest in the study of the evolution of regu...

    Authors: Francisco J. Romero-Campero, Ignacio Perez-Hurtado, Eva Lucas-Reina, Jose M. Romero and Federico Valverde
    Citation: BMC Genomics 2016 17:227
    Content type: Research article Published on:

  32. Intersexual genomic conflict sometimes leads to unequal expression of paternal and maternal alleles in offspring, resulting in parent-of-origin effects. In honey bees reciprocal crosses can show strong parent-...

    Authors: Emily J. Remnant, Alyson Ashe, Paul E. Young, Gabriele Buchmann, Madeleine Beekman, Michael H. Allsopp, Catherine M. Suter, Robert A. Drewell and Benjamin P. Oldroyd
    Citation: BMC Genomics 2016 17:226
    Content type: Research article Published on:

  33. The role of random mutations and genetic errors in defining the etiology of cancer and other multigenic diseases has recently received much attention. With the view that complex genes should be particularly vu...

    Authors: Aleksandr B. Sahakyan and Shankar Balasubramanian
    Citation: BMC Genomics 2016 17:225
    Content type: Research article Published on:

  34. Genetic variation in both the composition and distribution of fat and muscle in the body is important to human health as well as the healthiness and value of meat from cattle and sheep. Here we use detailed ph...

    Authors: Sunduimijid Bolormaa, Ben J. Hayes, Julius H.J. van der Werf, David Pethick, Michael E. Goddard and Hans D. Daetwyler
    Citation: BMC Genomics 2016 17:224
    Content type: Research article Published on:

  35. Multidrug and toxic compound extrusion (MATE) family is an important group of the multidrug efflux transporters that extrude organic compounds, transporting a broad range of substrates such as organic acids, p...

    Authors: Juge Liu, Yang Li, Wei Wang, Junyi Gai and Yan Li
    Citation: BMC Genomics 2016 17:223
    Content type: Research article Published on:

  36. Type VII protein secretion (T7SS) is a specialised system for excreting extracellular proteins across bacterial cell membranes and has been associated with virulence in Staphylococcus aureus. The genetic diversit...

    Authors: Ben Warne, Catriona P. Harkins, Simon R. Harris, Alexandra Vatsiou, Nicola Stanley-Wall, Julian Parkhill, Sharon J. Peacock, Tracy Palmer and Matthew T. G. Holden
    Citation: BMC Genomics 2016 17:222
    Content type: Research article Published on:

  37. Mitotic terminally differentiated photoreceptors (PRs) are observed in early retinal degeneration (erd), an inherited canine retinal disease driven by mutations in the NDR kinase STK38L (NDR2).

    Authors: Kristin L. Gardiner, Louise Downs, Agnes I. Berta-Antalics, Evelyn Santana, Gustavo D. Aguirre and Sem Genini
    Citation: BMC Genomics 2016 17:221
    Content type: Research article Published on:

  38. Recent advances in sequencing technology have opened a new era in RNA studies. Novel types of RNAs such as long non-coding RNAs (lncRNAs) have been discovered by transcriptomic sequencing and some lncRNAs have...

    Authors: Mei-Ju May Chen, Li-Kai Chen, Yu-Shing Lai, Yu-Yu Lin, Dung-Chi Wu, Yi-An Tung, Kwei-Yan Liu, Hsueh-Tzu Shih, Yi-Jyun Chen, Yan-Liang Lin, Li-Ting Ma, Jian-Long Huang, Po-Chun Wu, Ming-Yi Hong, Fang-Hua Chu, June-Tai Wu…
    Citation: BMC Genomics 2016 17:220
    Content type: Research article Published on:

  39. Grapevine phylloxera, an insect related to true aphids, is a major historic pest of viticulture only controlled through the selection of resistant rootstocks or through quarantine regulations where grapevine i...

    Authors: Claude Rispe, Fabrice Legeai, Daciana Papura, Anthony Bretaudeau, Sylvie Hudaverdian, Gaël Le Trionnaire, Denis Tagu, Julie Jaquiéry and François Delmotte
    Citation: BMC Genomics 2016 17:219
    Content type: Research article Published on:

  40. Clinical and subclinical endometritis are known to affect the fertility of dairy cows by inducing uterine inflammation. We hypothesized that clinical or subclinical endometritis could affect the fertility of c...

    Authors: Dessie Salilew-Wondim, Sally Ibrahim, Samuel Gebremedhn, Dawit Tesfaye, Maike Heppelmann, Heinrich Bollwein, Christiane Pfarrer, Ernst Tholen, Christiane Neuhoff, Karl Schellander and Michael Hoelker
    Citation: BMC Genomics 2016 17:218
    Content type: Research article Published on:

  41. Controlling and managing the breeding of bluefin tuna (Thunnus spp.) in captivity is an imperative step towards obtaining a sustainable supply of these fish in aquaculture production systems. Germ cell transplant...

    Authors: Ido Bar, Scott Cummins and Abigail Elizur
    Citation: BMC Genomics 2016 17:217
    Content type: Research Article Published on:

  44. NGS (next generation sequencing) has been widely used in studies of biological processes, ranging from microbial evolution to cancer genomics. However, the error rate of NGS (0.1 % ~ 1 %) is still remaining a ...

    Authors: Kaile Wang, Qin Ma, Lan Jiang, Shujuan Lai, Xuemei Lu, Yali Hou, Chung-I Wu and Jue Ruan
    Citation: BMC Genomics 2016 17:214
    Content type: Methodology article Published on:

    The Erratum to this article has been published in BMC Genomics 2016 17:421

  45. Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability and thus the ...

    Authors: Marcos V. A. Lemos, Hermenegildo Lucas Justino Chiaia, Mariana Piatto Berton, Fabieli L. B. Feitosa, Carolyn Aboujaoud, Gregório M. F. Camargo, Angélica S. C. Pereira, Lucia G. Albuquerque, Adrielle M. Ferrinho, Lenise F. Mueller, Monica R. Mazalli, Joyce J. M. Furlan, Roberto Carvalheiro, Daniel M. Gordo, Rafael Tonussi, Rafael Espigolan…
    Citation: BMC Genomics 2016 17:213
    Content type: Research article Published on:

  46. Gastrodia elata Blume (Orchidaceae) is an important Chinese medicine with several functional components. In the life cycle of G. elata, the orchid develops a symbiotic relationship wit...

    Authors: Chi-Chu Tsai, Keh-Ming Wu, Tzen-Yuh Chiang, Chun-Yen Huang, Chang-Hung Chou, Shu-Ju Li and Yu-Chung Chiang
    Citation: BMC Genomics 2016 17:212
    Content type: Research article Published on:

  48. Multi-layer perceptron (MLP) and radial basis function neural networks (RBFNN) have been shown to be effective in genome-enabled prediction. Here, we evaluated and compared the classification performance of an...

    Authors: Juan Manuel González-Camacho, José Crossa, Paulino Pérez-Rodríguez, Leonardo Ornella and Daniel Gianola
    Citation: BMC Genomics 2016 17:208
    Content type: Research article Published on:

  49. Unraveling the ancestry of ‘Afro-American’ communities is hampered by the complex demographic processes that took place during the Transatlantic Slave Trade (TAST) and the (post-)colonization periods. ‘Afro-Bo...

    Authors: Jacobo Pardo-Seco, Tanja Heinz, Patricia Taboada-Echalar, Federico Martinón-Torres and Antonio Salas
    Citation: BMC Genomics 2016 17:207
    Content type: Research article Published on:

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BMC Genomics

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