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  1. Vertebrate organogenesis is a highly complex process involving sequential cascades of transcription factor activation or repression. Interestingly a single developmental control gene can occasionally be essent...

    Authors: Sumantra Chatterjee, V Sivakamasundari, Sook Peng Yap, Petra Kraus, Vibhor Kumar, Xing Xing, Siew Lan Lim, Joel Sng, Shyam Prabhakar and Thomas Lufkin
    Citation: BMC Genomics 2014 15:1072
    Content type: Research article Published on:

  2. Lactobacillus crispatus is a ubiquitous micro-organism encountered in a wide range of host-associated habitats. It can be recovered from the gastrointestinal tract of animals and it is a common constituent of the...

    Authors: Teija Ojala, Matti Kankainen, Joana Castro, Nuno Cerca, Sanna Edelman, Benita Westerlund-Wikström, Lars Paulin, Liisa Holm and Petri Auvinen
    Citation: BMC Genomics 2014 15:1070
    Content type: Research article Published on:

  3. A previous study reported a comprehensive quantitative trait locus (QTL) and genome wide association study (GWAS) of southern leaf blight (SLB) resistance in the maize Nested Association Mapping (NAM) panel. S...

    Authors: Yang Bian, Qin Yang, Peter J Balint-Kurti, Randall J Wisser and James B Holland
    Citation: BMC Genomics 2014 15:1068
    Content type: Research article Published on:

  4. The reliable identification of proteins containing 50 or fewer amino acids is difficult due to the limited information content in short sequences. The 37 amino acid CydX protein in Escherichia coli is a member of...

    Authors: Rondine J Allen, Evan P Brenner, Caitlin E VanOrsdel, Jessica J Hobson, David J Hearn and Matthew R Hemm
    Citation: BMC Genomics 2014 15:946
    Content type: Research article Published on:

  5. Bacteria in the genus Ruminococcus are ubiquitous members of the mammalian gastrointestinal tract. In particular, they are important in ruminants where they digest a wide range of plant cell wall polysaccharides....

    Authors: Melissa R Christopherson, John A Dawson, David M Stevenson, Andrew C Cunningham, Shanti Bramhacharya, Paul J Weimer, Christina Kendziorski and Garret Suen
    Citation: BMC Genomics 2014 15:1066
    Content type: Research article Published on:

  6. Corynebacterium pseudotuberculosis biovar ovis is a facultative intracellular pathogen, and the etiological agent of caseous lymphadenitis in small ruminants. During the infection process, the bacterium is subjec...

    Authors: Wanderson M Silva, Rodrigo D Carvalho, Siomar C Soares, Isabela FS Bastos, Edson L Folador, Gustavo HMF Souza, Yves Le Loir, Anderson Miyoshi, Artur Silva and Vasco Azevedo
    Citation: BMC Genomics 2014 15:1065
    Content type: Research article Published on:

  7. In the filamentous cyanobacterium Nostoc punctiforme ATCC 29133, removal of combined nitrogen induces the differentiation of heterocysts, a cell-type specialized in N2 fixation. The differentiation involves genom...

    Authors: Gustaf Sandh, Margareta Ramström and Karin Stensjö
    Citation: BMC Genomics 2014 15:1064
    Content type: Research article Published on:

  9. A low birth weight has been extensively related to poor adult health outcomes. Birth weight can be seen as a proxy for environmental conditions during prenatal development. Identical twin pairs discordant for ...

    Authors: Qihua Tan, Morten Frost, Bastiaan T Heijmans, Jacob von Bornemann Hjelmborg, Elmar W Tobi, Kaare Christensen and Lene Christiansen
    Citation: BMC Genomics 2014 15:1062
    Content type: Research article Published on:

  10. Largely because of their direct, negative impacts on human health, the venoms of front-fanged snakes of the families Viperidae and Elapidae have been extensively characterized proteomically, transcriptomically...

    Authors: James J McGivern, Kenneth P Wray, Mark J Margres, Michelle E Couch, Stephen P Mackessy and Darin R Rokyta
    Citation: BMC Genomics 2014 15:1061
    Content type: Research article Published on:

  11. The wine industry needs better-adapted yeasts to grow at low temperature because it is interested in fermenting at low temperature to improve wine aroma. Elucidating the response to cold in Saccharomyces cerevisi...

    Authors: Estéfani García-Ríos, María López-Malo and José Manuel Guillamón
    Citation: BMC Genomics 2014 15:1059
    Content type: Research article Published on:

  12. The in vivo gene response associated with hyperthermia is poorly understood. Here, we perform a global, multiorgan characterization of the gene response to heat stress using an in vivo conscious rat model.

    Authors: Jonathan D Stallings, Danielle L Ippolito, Vineet Rakesh, Christine E Baer, William E Dennis, Bryan G Helwig, David A Jackson, Lisa R Leon, John A Lewis and Jaques Reifman
    Citation: BMC Genomics 2014 15:1058
    Content type: Research article Published on:

  13. The oral GPCR nutrient/taste receptor gene repertoire consists of the Tas1r family (sweet and umami tastes), the Tas2r family (bitter taste) as well as several other potential candidate sensors of amino acids, pe...

    Authors: Elizabete C da Silva, Nadia de Jager, William Burgos-Paz, Antonio Reverter, Miguel Perez-Enciso and Eugeni Roura
    Citation: BMC Genomics 2014 15:1057
    Content type: Research article Published on:

  14. Understanding gene expression and metabolic re-programming that occur in response to limiting nitrogen (N) conditions in crop plants is crucial for the ongoing progress towards the development of varieties wit...

    Authors: Viktoriya Coneva, Caitlin Simopoulos, José A Casaretto, Ashraf El-kereamy, David R Guevara, Jonathan Cohn, Tong Zhu, Lining Guo, Danny C Alexander, Yong-Mei Bi, Paul D McNicholas and Steven J Rothstein
    Citation: BMC Genomics 2014 15:1056
    Content type: Research article Published on:

  15. Neonicotinoid insecticides are widely known for their broad-spectrum control of arthropod pests. Recently, their effects on plant physiological mechanisms have been characterized as producing a stress shield, ...

    Authors: Mitchell D Stamm, Laramy S Enders, Teresa J Donze-Reiner, Frederick P Baxendale, Blair D Siegfried and Tiffany M Heng-Moss
    Citation: BMC Genomics 2014 15:1055
    Content type: Research article Published on:

  16. Lactococcus lactis is the most used species in the dairy industry. Its ability to adapt to technological stresses, such as oxidative stress encountered during stirring in the first stages of the cheese-making pro...

    Authors: Marina Cretenet, Gwenaëlle Le Gall, Udo Wegmann, Sergine Even, Claire Shearman, Régis Stentz and Sophie Jeanson
    Citation: BMC Genomics 2014 15:1054
    Content type: Research article Published on:

  17. Research on the aryl hydrocarbon receptor (AHR) has largely focused on variations in toxic outcomes resulting from its activation by halogenated aromatic hydrocarbons. But the AHR also plays key roles in regul...

    Authors: Ren X Sun, Lauren C Chong, Trent T Simmons, Kathleen E Houlahan, Stephenie D Prokopec, John D Watson, Ivy D Moffat, Sanna Lensu, Jere Lindén, Christine P'ng, Allan B Okey, Raimo Pohjanvirta and Paul C Boutros
    Citation: BMC Genomics 2014 15:1053
    Content type: Research article Published on:

  18. Changes to the environment as a result of human activities can result in a range of impacts on reef building corals that include coral bleaching (reduced concentrations of algal symbionts), decreased coral gro...

    Authors: Nedeljka Rosic, Paulina Kaniewska, Chon-Kit Kenneth Chan, Edmund Yew Siang Ling, David Edwards, Sophie Dove and Ove Hoegh-Guldberg
    Citation: BMC Genomics 2014 15:1052
    Content type: Research article Published on:

  19. Global change will affect patterns of nutrient upwelling in marine environments, potentially becoming even stricter regulators of phytoplankton primary productivity. To better understand phytoplankton nutrient...

    Authors: Sebastian D Rokitta, Peter Von Dassow, Björn Rost and Uwe John
    Citation: BMC Genomics 2014 15:1051
    Content type: Research article Published on:

  20. Chrysanthemum is an important ornamental plant all over the world. It is easily attacked by aphid, Macrosiphoniella sanbourni. The molecular mechanisms of plant defense responses to aphid are only partially under...

    Authors: Xiaolong Xia, Yafeng Shao, Jiafu Jiang, Liping Ren, Fadi Chen, Weimin Fang, Zhiyong Guan and Sumei Chen
    Citation: BMC Genomics 2014 15:1050
    Content type: Research article Published on:

  22. Genomic selection (GS) may improve selection response over conventional pedigree-based selection if markers capture more detailed information than pedigrees in recently domesticated tree species and/or make it...

    Authors: Jean Beaulieu, Trevor K Doerksen, John MacKay, André Rainville and Jean Bousquet
    Citation: BMC Genomics 2014 15:1048
    Content type: Research article Published on:

  23. In eukaryotes, transcriptional regulation is usually mediated by interactions of multiple transcription factors (TFs) with their respective specific cis-regulatory elements (CREs) in the so-called cis-regulatory ...

    Authors: Meng Niu, Ehsan S Tabari and Zhengchang Su
    Citation: BMC Genomics 2014 15:1047
    Content type: Methodology article Published on:

  24. Availability of molecular markers has proven to be an efficient tool in facilitating progress in plant breeding, which is particularly important in the case of less researched crops such as cotton. Considering...

    Authors: Ximei Li, Wenhui Gao, Huanle Guo, Xianlong Zhang, David D Fang and Zhongxu Lin
    Citation: BMC Genomics 2014 15:1046
    Content type: Research article Published on:

  25. RNA-seq studies have an important role for both large-scale analysis of gene expression and for transcriptome reconstruction. However, the lack of software specifically developed for the analysis of the transc...

    Authors: Alessandro Sardu, Laura Treu and Stefano Campanaro
    Citation: BMC Genomics 2014 15:1045
    Content type: Research article Published on:

  26. Driver mutations are positively selected during the evolution of cancers. The relative frequency of a particular mutation within a gene is typically used as a criterion for identifying a driver mutation. Howev...

    Authors: Jason Roszik and Scott E Woodman
    Citation: BMC Genomics 2014 15:1044
    Content type: Methodology article Published on:

  27. Scab, caused by the fungus Venturia inaequalis, is one of the most important diseases of cultivated apple. While a few scab resistance genes (R genes) governing qualitative resistance have been isolated and chara...

    Authors: Héloïse Bastiaanse, Yordan Muhovski, Olivier Parisi, Roberta Paris, Dominique Mingeot and Marc Lateur
    Citation: BMC Genomics 2014 15:1043
    Content type: Research article Published on:

  29. Dirofilaria immitis, or canine heartworm, is a filarial nematode parasite that infects dogs and other mammals worldwide. Current disease control relies on regular administration of anthelmintic preventives, howev...

    Authors: Ashley N Luck, Christopher C Evans, Molly D Riggs, Jeremy M Foster, Andrew R Moorhead, Barton E Slatko and Michelle L Michalski
    Citation: BMC Genomics 2014 15:1041
    Content type: Research article Published on:

  31. Mutations that alter chromosomal structure play critical roles in evolution and disease, including in the origin of new lifestyles and pathogenic traits in microbes. Large-scale rearrangements in genomes are o...

    Authors: Jeffrey E Barrick, Geoffrey Colburn, Daniel E Deatherage, Charles C Traverse, Matthew D Strand, Jordan J Borges, David B Knoester, Aaron Reba and Austin G Meyer
    Citation: BMC Genomics 2014 15:1039
    Content type: Software Published on:

  32. Only a small fraction of the mosquito species of the genus Anopheles are able to transmit malaria, one of the biggest killer diseases of poverty, which is mostly prevalent in the tropics. This diversity has ge...

    Authors: Vicky Dritsou, Elena Deligianni, Emmanuel Dialynas, James Allen, Nikos Poulakakis, Christos Louis, Dan Lawson and Pantelis Topalis
    Citation: BMC Genomics 2014 15:1038
    Content type: Research article Published on:

  33. Brassica napus (AACC) is self-compatible, although its ancestor species Brassica rapa (AA) and Brassica oleracea (CC) are self-incompatible. Most B.napus accessions have dominant self-compatibility (SC) resulting...

    Authors: Wen Zhai, Jianfeng Zhang, Yong Yang, Chaozhi Ma, Zhiquan Liu, Changbin Gao, Guilong Zhou, Jinxing Tu, Jinxiong Shen and Tingdong Fu
    Citation: BMC Genomics 2014 15:1037
    Content type: Research article Published on:

  34. DNA methylation is a heritable mechanism that acts in response to environmental changes, lifestyle and diseases by influencing gene expression in eukaryotes. Epigenetic studies of wild organisms are mandatory ...

    Authors: Alexandra Weyrich, Tino Schüllermann, Felix Heeger, Marie Jeschek, Camila J Mazzoni, Wei Chen, Kathrin Schumann and Joerns Fickel
    Citation: BMC Genomics 2014 15:1036
    Content type: Methodology article Published on:

  35. In metazoans, opsins are photosensitive proteins involved in both vision and non-visual photoreception. Echinoderms have no well-defined eyes but several opsin genes were found in the purple sea urchin (Strongylo...

    Authors: Jérôme Delroisse, Esther Ullrich-Lüter, Olga Ortega-Martinez, Sam Dupont, Maria-Ina Arnone, Jérôme Mallefet and Patrick Flammang
    Citation: BMC Genomics 2014 15:1035
    Content type: Research article Published on:

  36. Maternal nutrition during different stages of pregnancy can induce significant changes in the structure, physiology, and metabolism of the offspring. These changes could have important implications on food ani...

    Authors: Francisco Peñagaricano, Xin Wang, Guilherme JM Rosa, Amy E Radunz and Hasan Khatib
    Citation: BMC Genomics 2014 15:1034
    Content type: Research article Published on:

  37. Although Daphnia is increasingly recognized as a model for ecological genomics and biomedical research, there is, as of yet, no high-resolution genetic map for the genus. Such a map would provide an important too...

    Authors: Jarkko Routtu, Matthew D Hall, Brian Albere, Christian Beisel, R Daniel Bergeron, Anurag Chaturvedi, Jeong-Hyeon Choi, John Colbourne, Luc De Meester, Melissa T Stephens, Claus-Peter Stelzer, Eleanne Solorzano, W Kelley Thomas, Michael E Pfrender and Dieter Ebert
    Citation: BMC Genomics 2014 15:1033
    Content type: Research article Published on:

  38. Transposable elements form a significant proportion of eukaryotic genomes. Recently, Lexa et al. (Nucleic Acids Res 42:968-978, 2014) reported that plant long terminal repeat (LTR) retrotransposons often conta...

    Authors: Matej Lexa, Pavlina Steflova, Tomas Martinek, Michaela Vorlickova, Boris Vyskot and Eduard Kejnovsky
    Citation: BMC Genomics 2014 15:1032
    Content type: Research article Published on:

  39. Ecological studies routinely show genotype-genotype interactions between insects and their parasites. The mechanisms behind these interactions are not clearly understood. Using the bumblebee Bombus terrestris/try...

    Authors: Carolyn E Riddell, Juan D Lobaton Garces, Sally Adams, Seth M Barribeau, David Twell and Eamonn B Mallon
    Citation: BMC Genomics 2014 15:1031
    Content type: Research article Published on:

  40. Seedless grapes are greatly appreciated for fresh and dry fruit consumption. Parthenocarpy and stenospermocarpy have been described as the main phenomena responsible for seedlessness in Vitis vinifera. However, t...

    Authors: Chinedu Charles Nwafor, Ivana Gribaudo, Anna Schneider, Ron Wehrens, Maria Stella Grando and Laura Costantini
    Citation: BMC Genomics 2014 15:1030
    Content type: Research article Published on:

  41. Wheat (Triticum aestivum L.) is an economically important grain crop. Two-dimensional gel-based approaches are limited by the low identification rate of proteins and lack of accurate protein quantitation. The rec...

    Authors: Chaoying Ma, Jianwen Zhou, Guanxing Chen, Yanwei Bian, Dongwen Lv, Xiaohui Li, Zhimin Wang and Yueming Yan
    Citation: BMC Genomics 2014 15:1029
    Content type: Research article Published on:

  42. Currently, in the era of post-genomics, immunology is facing a challenging problem to translate mutant phenotypes into gene functions based on high-throughput data, while taking into account the classification...

    Authors: Masahiro Ono, Reiko J Tanaka and Manabu Kano
    Citation: BMC Genomics 2014 15:1028
    Content type: Methodology article Published on:

  43. The genetic diversity observed among bacteriophages remains a major obstacle for the identification of homologs and the comparison of their functional modules. In the structural module, although several classe...

    Authors: Anne Lopes, Paulo Tavares, Marie-Agnès Petit, Raphaël Guérois and Sophie Zinn-Justin
    Citation: BMC Genomics 2014 15:1027
    Content type: Software Published on:

  44. Rice (Oryza sativa. L) is more sensitive to drought stress than other cereals, and large genotypic variation in drought tolerance (DT) exists within the cultivated rice gene pool and its wild relatives. Selective...

    Authors: Liyu Huang, Fan Zhang, Fan Zhang, Wensheng Wang, Yongli Zhou, Binying Fu and Zhikang Li
    Citation: BMC Genomics 2014 15:1026
    Content type: Research article Published on:

  45. Eukaryotic cellular machineries are intricately regulated by several molecular mechanisms involving transcriptional control, post-translational control and post-translational modifications of proteins (PTMs). ...

    Authors: Rajan Pandey, Asif Mohmmed, Christine Pierrot, Jamal Khalife, Pawan Malhotra and Dinesh Gupta
    Citation: BMC Genomics 2014 15:1024
    Content type: Research article Published on:

  47. The admixed South African Coloured population is ideally suited to the discovery of tuberculosis susceptibility genetic variants and their probable ethnic origins, but previous attempts at finding such variant...

    Authors: Michelle Daya, Lize van der Merwe, Christopher R Gignoux, Paul D van Helden, Marlo Möller and Eileen G Hoal
    Citation: BMC Genomics 2014 15:1021
    Content type: Research article Published on:

  48. Acinetobacter baumannii is a significant hospital pathogen, particularly due to the dissemination of highly multidrug resistant isolates. Genome data have revealed that A. baumannii is highly genetically diverse,...

    Authors: Bart A Eijkelkamp, Uwe H Stroeher, Karl A Hassan, Ian T Paulsen and Melissa H Brown
    Citation: BMC Genomics 2014 15:1020
    Content type: Research article Published on:

  49. Our prior characterization of RasGrf1 deficient mice uncovered significant defects in pancreatic islet count and size as well as beta cell development and signaling function, raising question about the mechani...

    Authors: Lara Manyes, Monica Arribas, Carmela Gomez, Nuria Calzada, Alberto Fernandez-Medarde and Eugenio Santos
    Citation: BMC Genomics 2014 15:1019
    Content type: Research article Published on:

  50. The elevated expression of enzymes with insecticide metabolism activity can lead to high levels of insecticide resistance in the malaria vector, Anopheles gambiae. In this study, adult female mosquitoes from an i...

    Authors: Victoria A Ingham, Christopher M Jones, Patricia Pignatelli, Vasileia Balabanidou, John Vontas, Simon C Wagstaff, Jonathan D Moore and Hilary Ranson
    Citation: BMC Genomics 2014 15:1018
    Content type: Research article Published on:

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BMC Genomics

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