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  1. High density genotyping data are indispensable for genomic analyses of complex traits in animal and crop species. Maize is one of the most important crop plants worldwide, however a high density SNP genotyping...

    Authors: Sandra Unterseer, Eva Bauer, Georg Haberer, Michael Seidel, Carsten Knaak, Milena Ouzunova, Thomas Meitinger, Tim M Strom, Ruedi Fries, Hubert Pausch, Christofer Bertani, Alessandro Davassi, Klaus FX Mayer and Chris-Carolin Schön
    Citation: BMC Genomics 2014 15:823
    Content type: Research article Published on:

  2. Metarhizium anisopliae is an entomopathogenic fungus used in the biological control of some agricultural insect pests, and efforts are underway to use this fungus in the control of insect-borne human diseases. A ...

    Authors: Charley Christian Staats, Ângela Junges, Rafael Lucas Muniz Guedes, Claudia Elizabeth Thompson, Guilherme Loss de Morais, Juliano Tomazzoni Boldo, Luiz Gonzaga Paula de Almeida, Fábio Carrer Andreis, Alexandra Lehmkuhl Gerber, Nicolau Sbaraini, Rana Louise de Andrade da Paixão, Leonardo Broetto, Melissa Landell, Lucélia Santi, Walter Orlando Beys-da-Silva, Carolina Pereira Silveira…
    Citation: BMC Genomics 2014 15:822
    Content type: Research article Published on:

  3. The basic helix-loop-helix transcription factor Twist1 has well-documented roles in progenitor populations of the developing embryo, including endocardial cushions (ECC) and limb buds, and also in cancer. Whet...

    Authors: Mary P Lee, Nancy Ratner and Katherine E Yutzey
    Citation: BMC Genomics 2014 15:821
    Content type: Research article Published on:

  4. Wing discs of B. mori are transformed to pupal wings during the larva-to-pupa metamorphosis with dramatic morphological and structural changes. To understand these changes at a transcriptional level, RNA-seq of t...

    Authors: Jun Ou, Hui-Min Deng, Si-Chun Zheng, Li-Hua Huang, Qi-Li Feng and Lin Liu
    Citation: BMC Genomics 2014 15:820
    Content type: Research article Published on:

  5. The polytene nuclei of the dipteran Chironomus tentans (Ch. tentans) with their Balbiani ring (BR) genes constitute an exceptional model system for studies of the expression of endogenous eukaryotic genes. Here, ...

    Authors: Alexey Kutsenko, Thomas Svensson, Björn Nystedt, Joakim Lundeberg, Petra Björk, Erik Sonnhammer, Stefania Giacomello, Neus Visa and Lars Wieslander
    Citation: BMC Genomics 2014 15:819
    Content type: Research article Published on:

  6. Transcription factors (TFs) contain DNA-binding domains (DBDs) and regulate gene expression by binding to specific DNA sequences. In addition, there are proteins, called transcription coregulators (TCs), which...

    Authors: Jinn-Jy Lin, Chun-Ping Yu, Yao-Ming Chang, Sean Chun-Chang Chen and Wen-Hsiung Li
    Citation: BMC Genomics 2014 15:818
    Content type: Research article Published on:

  7. Pyrethroid resistance in the major malaria vector Anopheles funestus is rapidly expanding across Southern Africa. It remains unknown whether this resistance has a unique origin with the same molecular basis or is...

    Authors: Jacob M Riveron, Sulaiman S Ibrahim, Emmanuel Chanda, Themba Mzilahowa, Nelson Cuamba, Helen Irving, Kayla G Barnes, Miranda Ndula and Charles S Wondji
    Citation: BMC Genomics 2014 15:817
    Content type: Research article Published on:

  8. The passion fruit (Passiflora edulis) is a tropical crop of economic importance both for juice production and consumption as fresh fruit. The juice is also used in concentrate blends that are consumed worldwide. ...

    Authors: Anselmo Azevedo Santos, Helen Alves Penha, Arnaud Bellec, Carla de Freitas Munhoz, Andrea Pedrosa-Harand, Hélène Bergès and Maria Lucia Carneiro Vieira
    Citation: BMC Genomics 2014 15:816
    Content type: Research article Published on:

  9. Carbapenem-resistance in Acinetobacter baumannii has gradually become a global challenge. To identify the genes involved in carbapenem resistance in A. baumannii, the transcriptomic responses of the completely se...

    Authors: Kai-Chih Chang, Han-Yueh Kuo, Chuan Yi Tang, Cheng-Wei Chang, Chia-Wei Lu, Chih-Chin Liu, Huei-Ru Lin, Kuan-Hsueh Chen and Ming-Li Liou
    Citation: BMC Genomics 2014 15:815
    Content type: Research article Published on:

  10. High dose ionizing radiation (IR) induces potent toxic cell effects mediated by either direct DNA damage or the production of reactive oxygen species (ROS). IR-induced modulations in multiple biological proces...

    Authors: Lucian Beer, Rudolf Seemann, Robin Ristl, Adolf Ellinger, Mohammad Mahdi Kasiri, Andreas Mitterbauer, Matthias Zimmermann, Christian Gabriel, Mariann Gyöngyösi, Walter Klepetko, Michael Mildner and Hendrik Jan Ankersmit
    Citation: BMC Genomics 2014 15:814
    Content type: Research article Published on:

  11. Bacteria of genus Thermus inhabit both man-made and natural thermal environments. Several Thermus species have shown biotechnological potential such as reduction of heavy metals which is essential for eradication...

    Authors: Benjamin Kumwenda, Derek Litthauer and Oleg Reva
    Citation: BMC Genomics 2014 15:813
    Content type: Research article Published on:

  12. Peptidases are key proteins involved in essential plant physiological processes. Although protein peptidase inhibitors are essential molecules that modulate peptidase activity, their global presence in differe...

    Authors: María Estrella Santamaría, Mercedes Diaz-Mendoza, Isabel Diaz and Manuel Martinez
    Citation: BMC Genomics 2014 15:812
    Content type: Research article Published on:

  13. Epigenetic modifications (especially altered DNA methylation) resulting in altered gene expression may be one reason for development failure or abnormalities in cloned animals, but the underlying mechanism of ...

    Authors: Guanglei Li, Qitao Jia, Jianguo Zhao, Xinyun Li, Mei Yu, Melissa S Samuel, Shuhong Zhao, Randall S Prather and Changchun Li
    Citation: BMC Genomics 2014 15:811
    Content type: Research article Published on:

  14. Ashbya gossypii is an industrially relevant microorganism traditionally used for riboflavin production. Despite the high gene homology and gene order conservation comparatively with Saccharomyces cerevisiae, it p...

    Authors: Daniel Gomes, Tatiana Q Aguiar, Oscar Dias, Eugénio C Ferreira, Lucília Domingues and Isabel Rocha
    Citation: BMC Genomics 2014 15:810
    Content type: Research article Published on:

  15. Sudden death syndrome (SDS) is a serious threat to soybean production that can be managed with host plant resistance. To dissect the genetic architecture of quantitative resistance to the disease in soybean, t...

    Authors: Zixiang Wen, Ruijuan Tan, Jiazheng Yuan, Carmille Bales, Wenyan Du, Shichen Zhang, Martin I Chilvers, Cathy Schmidt, Qijian Song, Perry B Cregan and Dechun Wang
    Citation: BMC Genomics 2014 15:809
    Content type: Research article Published on:

  16. There is growing interest in odonates (damselflies and dragonflies) as model organisms in ecology and evolutionary biology but the development of genomic resources has been slow. So far only one draft genome (Lad...

    Authors: Pallavi Chauhan, Bengt Hansson, Ken Kraaijeveld, Peter de Knijff, Erik I Svensson and Maren Wellenreuther
    Citation: BMC Genomics 2014 15:808
    Content type: Research article Published on:

  17. Growth regulating factors (GRFs) have been shown to play important roles in plant growth and development. GRF genes represent a large multigene family in plants. Recently, genome-wide structural and evolutiona...

    Authors: Fengde Wang, Nianwei Qiu, Qian Ding, Jingjuan Li, Yihui Zhang, Huayin Li and Jianwei Gao
    Citation: BMC Genomics 2014 15:807
    Content type: Research article Published on:

  19. Litchi is an evergreen woody tree widely cultivated in subtropical and tropical regions. Defective flowering is a major challenge for litchi production in time of climate change and global warming. Previous st...

    Authors: Xingyu Lu, Hyeji Kim, Silin Zhong, Houbin Chen, Zhiqun Hu and Biyan Zhou
    Citation: BMC Genomics 2014 15:805
    Content type: Research article Published on:

  20. The tropical green-lipped mussel Perna viridis is a common biomonitor throughout the Indo-Pacific region that is used for environmental monitoring and ecotoxicological investigations. However, there is limited mo...

    Authors: Priscilla TY Leung, Jack CH Ip, Sarah ST Mak, Jian Wen Qiu, Paul KS Lam, Chris KC Wong, Leo L Chan and Kenneth MY Leung
    Citation: BMC Genomics 2014 15:804
    Content type: Research article Published on:

  21. Whole-genome sequencing is an important method to understand the genetic information, gene function, biological characteristics and survival mechanisms of organisms. Sequencing large genomes is very simple at ...

    Authors: Shuguang Lu, Shuai Le, Yinling Tan, Ming Li, Chang Liu, Kebin Zhang, Jianjun Huang, Haimei Chen, Xiancai Rao, Junmin Zhu, Lingyun Zou, Qingshan Ni, Shu Li, Jing Wang, Xiaolin Jin, Qiwen Hu…
    Citation: BMC Genomics 2014 15:803
    Content type: Research article Published on:

  22. Endothelial progenitor cells (EPCs) play a fundamental role in not only blood vessel development but also post-natal vascular repair. Currently EPCs are defined as early and late EPCs based on their biological...

    Authors: Ting-Yu Chang, Tse-Shun Huang, Hsei-Wei Wang, Shing-Jyh Chang, Hung-Hao Lo, Ya-Lin Chiu, Yen-Li Wang, Chung-Der Hsiao, Chin-Han Tsai, Chia-Hao Chan, Ren-In You, Chun-Hsien Wu, Tsung-Neng Tsai, Shu-Meng Cheng and Cheng-Chung Cheng
    Citation: BMC Genomics 2014 15:802
    Content type: Research article Published on:

  23. The local environment plays a major role in the spatial distribution of plant populations. Natural plant populations have an extremely poor displacing capacity, so their continued survival in a given environme...

    Authors: Matteo Dell’Acqua, Andrea Zuccolo, Metin Tuna, Luca Gianfranceschi and Mario Enrico Pè
    Citation: BMC Genomics 2014 15:801
    Content type: Research article Published on:

  24. Nucleotide metabolism is central to all biological systems, due to their essential role in genetic information and energy transfer, which in turn suggests its possible presence in the last common ancestor (LCA...

    Authors: Dagoberto Armenta-Medina, Lorenzo Segovia and Ernesto Perez-Rueda
    Citation: BMC Genomics 2014 15:800
    Content type: Research article Published on:

  25. The vertebrate brain plays a critical role in the regulation of sexual maturation and reproduction by integrating environmental information with developmental and endocrine status. The European eel Anguilla angui...

    Authors: Allison M Churcher, Jose Martin Pujolar, Massimo Milan, Peter C Hubbard, Rute ST Martins, João L Saraiva, Mar Huertas, Luca Bargelloni, Tomaso Patarnello, Ilaria AM Marino, Lorenzo Zane and Adelino VM Canário
    Citation: BMC Genomics 2014 15:799
    Content type: Research article Published on:

  26. MicroRNAs (miRNAs) are an abundant class of small single-stranded non-coding RNA molecules ranging from 18 to 24 nucleotides. They negatively regulate gene expression at the post-transcriptional level and play...

    Authors: Clémence Desjardin, Anne Vaiman, Xavier Mata, Rachel Legendre, Johan Laubier, Sean P Kennedy, Denis Laloe, Eric Barrey, Claire Jacques, Edmond P Cribiu and Laurent Schibler
    Citation: BMC Genomics 2014 15:798
    Content type: Research article Published on:

  27. In pigs, the perinatal period is the most critical time for survival. Piglet maturation, which occurs at the end of gestation, leads to a state of full development after birth. Therefore, maturity is an import...

    Authors: Valentin Voillet, Magali SanCristobal, Yannick Lippi, Pascal GP Martin, Nathalie Iannuccelli, Christine Lascor, Florence Vignoles, Yvon Billon, Laurianne Canario and Laurence Liaubet
    Citation: BMC Genomics 2014 15:797
    Content type: Research article Published on:

  28. Belgian Blue cattle are famous for their exceptional muscular development or “double-muscling”. This defining feature emerged following the fixation of a loss-of-function variant in the myostatin gene in the e...

    Authors: Tom Druet, Naima Ahariz, Nadine Cambisano, Nico Tamma, Charles Michaux, Wouter Coppieters, Carole Charlier and Michel Georges
    Citation: BMC Genomics 2014 15:796
    Content type: Research article Published on:

  29. Mobile elements (MEs) constitute greater than 50% of the human genome as a result of repeated insertion events during human genome evolution. Although most of these elements are now fixed in the population, so...

    Authors: Jiantao Wu, Wan-Ping Lee, Alistair Ward, Jerilyn A Walker, Miriam K Konkel, Mark A Batzer and Gabor T Marth
    Citation: BMC Genomics 2014 15:795
    Content type: Methodology article Published on:

  30. High intracellular levels of unbound iron can contribute to the production of reactive oxygen species (ROS) via the Fenton reaction, while depletion of iron limits the availability of iron-containing proteins,...

    Authors: Bernhard Remes, Bork A Berghoff, Konrad U Förstner and Gabriele Klug
    Citation: BMC Genomics 2014 15:794
    Content type: Research article Published on:

  31. Phage ZZ1, which efficiently infects pathogenic Acinetobacter baumannii strains, is the fifth completely sequenced T4-like Acinetobacter phage to date. To gain a better understanding of the genetic characteristic...

    Authors: Jing Jin, Zhen-Jiang Li, Shu-Wei Wang, Shan-Mei Wang, Song-Jian Chen, De-Hai Huang, Gai Zhang, Ya-Hui Li, Xiao-Ting Wang, Jin Wang and Guo-Qiang Zhao
    Citation: BMC Genomics 2014 15:793
    Content type: Research article Published on:

  32. Galileo is one of three members of the P superfamily of DNA transposons. It was originally discovered in Drosophila buzzatii, in which three segregating chromosomal inversions were shown to have been generated by...

    Authors: Juliana W Gonçalves, Victor Hugo Valiati, Alejandra Delprat, Vera L S Valente and Alfredo Ruiz
    Citation: BMC Genomics 2014 15:792
    Content type: Research article Published on:

  33. Eukaryotic genomes are replicated during S phase according to a temporal program. Several determinants control the timing of origin firing, including the chromatin environment and epigenetic modifications. How...

    Authors: Ignacio Soriano, Esther C Morafraile, Enrique Vázquez, Francisco Antequera and Mónica Segurado
    Citation: BMC Genomics 2014 15:791
    Content type: Research article Published on:

  34. Female fertility is important for the maintenance of the production in a dairy cattle herd. Two QTL regions on BTA04 and on BTA13 previously detected in Nordic Holstein (NH) and validated in the Danish Jersey ...

    Authors: Johanna K Höglund, Goutam Sahana, Rasmus Froberg Brøndum, Bernt Guldbrandtsen, Bart Buitenhuis and Mogens S Lund
    Citation: BMC Genomics 2014 15:790
    Content type: Research article Published on:

  35. Hypercapnia and elevated temperatures resulting from climate change may have adverse consequences for many marine organisms. While diverse physiological and ecological effects have been identified, changes in ...

    Authors: Lars Harms, Stephan Frickenhaus, Melanie Schiffer, Felix Christopher Mark, Daniela Storch, Christoph Held, Hans-Otto Pörtner and Magnus Lucassen
    Citation: BMC Genomics 2014 15:789
    Content type: Research article Published on:

  36. More than 20% of the world’s population is at risk for infection by filarial nematodes and >180 million people worldwide are already infected. Along with infection comes significant morbidity that has a socioe...

    Authors: Luke J Tallon, Xinyue Liu, Sasisekhar Bennuru, Marcus C Chibucos, Alvaro Godinez, Sandra Ott, Xuechu Zhao, Lisa Sadzewicz, Claire M Fraser, Thomas B Nutman and Julie C Dunning Hotopp
    Citation: BMC Genomics 2014 15:788
    Content type: Research article Published on:

  37. Burkholderia pseudomallei, the causative agent of melioidosis, is a Gram-negative bacterium widely distributed in soil and water in endemic areas. This soil saprophyte can survive harsh environmental conditions, ...

    Authors: Siroj Jitprasutwit, Catherine Ong, Niramol Juntawieng, Wen Fong Ooi, Claudia M Hemsley, Paiboon Vattanaviboon, Richard W Titball, Patrick Tan and Sunee Korbsrisate
    Citation: BMC Genomics 2014 15:787
    Content type: Research article Published on:

  38. The koala, Phascolarctos cinereus, is a biologically unique and evolutionarily distinct Australian arboreal marsupial. The goal of this study was to sequence the transcriptome from several tissues of two geograph...

    Authors: Matthew Hobbs, Ana Pavasovic, Andrew G King, Peter J Prentis, Mark DB Eldridge, Zhiliang Chen, Donald J Colgan, Adam Polkinghorne, Marc R Wilkins, Cheyne Flanagan, Amber Gillett, Jon Hanger, Rebecca N Johnson and Peter Timms
    Citation: BMC Genomics 2014 15:786
    Content type: Research article Published on:

  39. A critical aspect of plant infection by the majority of pathogens is penetration of the plant cell wall. This process requires the production and secretion of a broad spectrum of pathogen enzymes that target a...

    Authors: Leila M Blackman, Darren P Cullerne and Adrienne R Hardham
    Citation: BMC Genomics 2014 15:785
    Content type: Research article Published on:

  40. Acute myeloid leukemia with complex karyotype (CK-AML) is a distinct biological entity associated with a very poor outcome. Since complex karyotypes frequently contain deletions of the chromosomal region 12p13...

    Authors: Simone Feurstein, Frank G Rücker, Lars Bullinger, Winfried Hofmann, Georgi Manukjan, Gudrun Göhring, Ulrich Lehmann, Michael Heuser, Arnold Ganser, Konstanze Döhner, Brigitte Schlegelberger and Doris Steinemann
    Citation: BMC Genomics 2014 15:784
    Content type: Research article Published on:

  41. RNA sequencing technologies reveal that bacteria express RNA molecules other than mRNA, rRNA or tRNA. During the last years genome-wide bacterial transcriptomes have been shown to comprise intergenic RNA, anti...

    Authors: María Gómez-Lozano, Rasmus L Marvig, Monica VL Tulstrup and Søren Molin
    Citation: BMC Genomics 2014 15:783
    Content type: Research article Published on:

  42. Introgression populations are used to make the genetic variation of unadapted germplasm or wild relatives of crops available for plant breeding. They consist of introgression lines that carry small chromosome ...

    Authors: Karen Christin Falke, Gregory S Mahone, Eva Bauer, Grit Haseneyer, Thomas Miedaner, Frank Breuer and Matthias Frisch
    Citation: BMC Genomics 2014 15:782
    Content type: Research article Published on:

  43. Little is known about the interplay between n-3 fatty acids and genetic variants for diabetes-related traits at the genome-wide level. The present study aimed to examine variance contributions of genotype by e...

    Authors: Ju-Sheng Zheng, Chao-Qiang Lai, Laurence D Parnell, Yu-Chi Lee, Jian Shen, Caren E Smith, Patricia Casas-Agustench, Kris Richardson, Duo Li, Sabrina E Noel, Katherine L Tucker, Donna K Arnett, Ingrid B Borecki and José M Ordovás
    Citation: BMC Genomics 2014 15:781
    Content type: Research article Published on:

  44. Wood formation in tree species is regulated by multiple factors at various layers. Alternative splicing (AS) occurs within a large number of genes in wood formation. However, the functional implications and co...

    Authors: Peng Xu, Yimeng Kong, Dongliang Song, Cheng Huang, Xuan Li and Laigeng Li
    Citation: BMC Genomics 2014 15:780
    Content type: Research article Published on:

  45. Adaptation of mammals to terrestrial life was facilitated by the unique vertebrate trait of body hair, which occurs in a range of morphological patterns. Keratin associated proteins (KRTAPs), the major structu...

    Authors: Imran Khan, Emanuel Maldonado, Vítor Vasconcelos, Stephen J O’Brien, Warren E Johnson and Agostinho Antunes
    Citation: BMC Genomics 2014 15:779
    Content type: Research article Published on:

  46. Defects in airway mucosal defense, including decreased mucus clearance, contribute to the pathogenesis of human chronic obstructive pulmonary diseases. Scnn1b-Tg mice, which exhibit chronic airway surface dehydra...

    Authors: Yogesh Saini, Hong Dang, Alessandra Livraghi-Butrico, Elizabeth J Kelly, Lisa C Jones, Wanda K O’Neal and Richard C Boucher
    Citation: BMC Genomics 2014 15:726
    Content type: Research article Published on:

  47. Current trends in sheep farming practices rely on animals with a greater level of behavioral autonomy than before, a phenotype that actively contributes to the sustainability of animal production. Social react...

    Authors: Dominique Hazard, Carole Moreno, Didier Foulquié, Eric Delval, Dominique François, Jacques Bouix, Guillaume Sallé and Alain Boissy
    Citation: BMC Genomics 2014 15:778
    Content type: Research article Published on:

  48. Cyanobacteria constitute a serious threat to freshwater ecosystems by producing toxic secondary metabolites, e.g. microcystins. These microcystins have been shown to harm livestock, pets and humans and to affe...

    Authors: Anke Schwarzenberger, Thomas Sadler, Susanne Motameny, Kamel Ben-Khalifa, Peter Frommolt, Janine Altmüller, Kathryn Konrad and Eric von Elert
    Citation: BMC Genomics 2014 15:776
    Content type: Research article Published on:

  49. The probable influence of genes and the environment on sex determination in Nile tilapia suggests that it should be regarded as a complex trait. Detection of sex determination genes in tilapia has both scienti...

    Authors: Orly Eshel, Andrey Shirak, Lior Dor, Mark Band, Tatyana Zak, Michal Markovich-Gordon, Vered Chalifa-Caspi, Esther Feldmesser, Joel I Weller, Eyal Seroussi, Gideon Hulata and Micha Ron
    Citation: BMC Genomics 2014 15:774
    Content type: Research article Published on:

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BMC Genomics

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