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  1. Sprague and Tatum (1942) introduced the concepts of general combining ability (GCA) and specific combining ability (SCA) to evaluate the breeding parents and F1 hybrid performance, respectively. Since then, th...

    Authors: Gaoyuan Song, Zhibin Guo, Zhenwei Liu, Xuefeng Qu, Daiming Jiang, Wei Wang, Yingguo Zhu and Daichang Yang
    Citation: BMC Genomics 2014 15:297
    Content type: Research article Published on:

  2. WUSCHEL (WUS)-related homeobox (WOX) protein family members play important roles in the maintenance and proliferation of the stem cell niche in the shoot apical meristem (SAM), root apical meristem (RAM), and ...

    Authors: Bobin Liu, Lin Wang, Jin Zhang, Jianbo Li, Huanquan Zheng, Jun Chen and Mengzhu Lu
    Citation: BMC Genomics 2014 15:296
    Content type: Research article Published on:

  4. The zygomycete fungi like Rhizomucor miehei have been extensively exploited for the production of various enzymes. As a thermophilic fungus, R. miehei is capable of growing at temperatures that approach the upper...

    Authors: Peng Zhou, Guoqiang Zhang, Shangwu Chen, Zhengqiang Jiang, Yanbin Tang, Bernard Henrissat, Qiaojuan Yan, Shaoqing Yang, Chin-Fu Chen, Bing Zhang and Zhenglin Du
    Citation: BMC Genomics 2014 15:294
    Content type: Research article Published on:

  5. Understanding the basis for volatile organic compound (VOC) biosynthesis and regulation is of great importance for the genetic improvement of fruit flavor. Lactones constitute an essential group of fatty acid-...

    Authors: José F Sánchez-Sevilla, Eduardo Cruz-Rus, Victoriano Valpuesta, Miguel A Botella and Iraida Amaya
    Citation: BMC Genomics 2014 15:218
    Content type: Research article Published on:

  6. There is interest in improving the flavor of commercial strawberry (Fragaria × ananassa) varieties. Fruit flavor is shaped by combinations of sugars, acids and volatile compounds. Many efforts seek to use genomic...

    Authors: Alan H Chambers, Jeremy Pillet, Anne Plotto, Jinhe Bai, Vance M Whitaker and Kevin M Folta
    Citation: BMC Genomics 2014 15:217
    Content type: Research article Published on:

  7. Using genome-wide genetic, gene expression, and microRNA expression (miRNA) data, we developed an integrative approach to investigate the genetic and epigenetic basis of chemotherapeutic sensitivity.

    Authors: Bonnie LaCroix, Eric R Gamazon, Divya Lenkala, Hae Kyung Im, Paul Geeleher, Dana Ziliak, Nancy J Cox and Rong Stephanie Huang
    Citation: BMC Genomics 2014 15:292
    Content type: Methodology article Published on:

  8. It has been shown previously that aminocoumarin antibiotics such as novobiocin lead to immediate downregulation of recA expression and thereby inhibit the SOS response, mutation frequency and recombination capaci...

    Authors: Wiebke Schröder, Jörg Bernhardt, Gabriella Marincola, Ludger Klein-Hitpass, Alexander Herbig, Guido Krupp, Kay Nieselt and Christiane Wolz
    Citation: BMC Genomics 2014 15:291
    Content type: Research article Published on:

  9. Bisulfite sequencing is the most efficient single nucleotide resolution method for analysis of methylation status at whole genome scale, but improved quality control metrics are needed to better standardize ex...

    Authors: Gary G Chen, Alpha B Diallo, Raphaël Poujol, Corina Nagy, Alfredo Staffa, Kathryn Vaillancourt, Pierre-Eric Lutz, Vanessa K Ota, Deborah C Mash, Gustavo Turecki and Carl Ernst
    Citation: BMC Genomics 2014 15:290
    Content type: Methodology article Published on:

  10. MicroRNAs (miRNAs) regulate various biological processes in plants. Considerable data are available on miRNAs involved in the development of rice, maize and barley. In contrast, little is known about miRNAs an...

    Authors: Ran Han, Chao Jian, Jinyang Lv, Yan Yan, Qing Chi, Zhanjie Li, Qian Wang, Jin Zhang, Xiangli Liu and Huixian Zhao
    Citation: BMC Genomics 2014 15:289
    Content type: Research article Published on:

  11. Single nucleotide polymorphisms (SNPs) are ideal signatures for subtyping monomorphic pathogens such as Bacillus anthracis. Here we report the use of next-generation sequencing technology to investigate the histo...

    Authors: Guillaume Girault, Yann Blouin, Gilles Vergnaud and Sylviane Derzelle
    Citation: BMC Genomics 2014 15:288
    Content type: Research article Published on:

  12. Intron-derived long noncoding RNAs with snoRNA ends (sno-lncRNAs) are highly expressed from the imprinted Prader-Willi syndrome (PWS) region on human chromosome 15. However, sno-lncRNAs from other regions of the ...

    Authors: Xiao-Ou Zhang, Qing-Fei Yin, Hai-Bin Wang, Yang Zhang, Tian Chen, Ping Zheng, Xuhua Lu, Ling-Ling Chen and Li Yang
    Citation: BMC Genomics 2014 15:287
    Content type: Research article Published on:

  13. Chorella is the representative taxon of Chlorellales in Trebouxiophyceae, and its chloroplast (cp) genomic information has been thought to depend only on studies concerning Chlorella vulgaris and GenBank informat...

    Authors: Haeyoung Jeong, Jong-Min Lim, Jihye Park, Young Mi Sim, Han-Gu Choi, Jungho Lee and Won-Joong Jeong
    Citation: BMC Genomics 2014 15:286
    Content type: Research article Published on:

  14. The date palm is one of the oldest cultivated fruit trees. It is critical in many ways to cultures in arid lands by providing highly nutritious fruit while surviving extreme heat and environmental conditions. ...

    Authors: Lisa S Mathew, Manuel Spannagl, Ameena Al-Malki, Binu George, Maria F Torres, Eman K Al-Dous, Eman K Al-Azwani, Emad Hussein, Sweety Mathew, Klaus FX Mayer, Yasmin Ali Mohamoud, Karsten Suhre and Joel A Malek
    Citation: BMC Genomics 2014 15:285
    Content type: Research article Published on:

  16. The pectinolytic enterobacteria of the Pectobacterium and Dickeya genera are causative agents of maceration-associated diseases affecting a wide variety of crops and ornamentals. For the past decade, the emergenc...

    Authors: Jacques Pédron, Samuel Mondy, Yannick Raoul des Essarts, Frédérique Van Gijsegem and Denis Faure
    Citation: BMC Genomics 2014 15:283
    Content type: Research article Published on:

  17. Ranking and identifying biomarkers that are associated with disease from genome-wide measurements holds significant promise for understanding the genetic basis of common diseases. The large number of single nu...

    Authors: Matthew E Stokes, M Michael Barmada, M Ilyas Kamboh and Shyam Visweswaran
    Citation: BMC Genomics 2014 15:282
    Content type: Methodology article Published on:

  18. Basic leucine zipper (bZIP) transcription factor gene family is one of the largest and most diverse families in plants. Current studies have shown that the bZIP proteins regulate numerous growth and developmen...

    Authors: Jinyi Liu, Nana Chen, Fei Chen, Bin Cai, Silvia Dal Santo, Giovanni Battista Tornielli, Mario Pezzotti and Zong-Ming (Max) Cheng
    Citation: BMC Genomics 2014 15:281
    Content type: Research article Published on:

  19. Ralstonia solanacearum, the causal agent of bacterial wilt, is a genetically diverse bacterial plant pathogen present in tropical and subtropical regions of the world that infects more than 200 plant species, inc...

    Authors: Ana M Bocsanczy, Ute CM Achenbach, Arianna Mangravita-Novo, Marjorie Chow and David J Norman
    Citation: BMC Genomics 2014 15:280
    Content type: Research article Published on:

  20. Negative energy balance (NEB) is an altered metabolic state in high yielding cows that occurs during the first few weeks postpartum when energy demands for lactation and maintenance exceed the energy supply fr...

    Authors: Attia Fatima, David J Lynn, Padraic O’Boyle, Cathal Seoighe and Dermot Morris
    Citation: BMC Genomics 2014 15:279
    Content type: Research article Published on:

  21. The large amounts of data generated by genomics, transcriptomics and proteomics have increased our understanding of the biology of Anaplasma marginale. However, these data have also led to new assumptions that re...

    Authors: Francy L Crosby, Heather L Wamsley, Melanie G Pate, Anna M Lundgren, Susan M Noh, Ulrike G Munderloh and Anthony F Barbet
    Citation: BMC Genomics 2014 15:278
    Content type: Research article Published on:

  22. MYB is the largest plant transcription factor gene family playing vital roles in plant growth and development. However, it has not been systematically studied in Salvia miltiorrhiza, an economically important med...

    Authors: Caili Li and Shanfa Lu
    Citation: BMC Genomics 2014 15:277
    Content type: Research article Published on:

  23. Bread wheat (Triticum aestivum) has a large, complex and hexaploid genome consisting of A, B and D homoeologous chromosome sets. Therefore each wheat gene potentially exists as a trio of A, B and D homoeoloci, ea...

    Authors: Lindsey J Leach, Eric J Belfield, Caifu Jiang, Carly Brown, Aziz Mithani and Nicholas P Harberd
    Citation: BMC Genomics 2014 15:276
    Content type: Research article Published on:

  24. Genetic markers are widely used to understand the biology and population dynamics of disease vectors, but often markers are limited in the resolution they provide. In particular, the delineation of population ...

    Authors: Gordana Rašić, Igor Filipović, Andrew R Weeks and Ary A Hoffmann
    Citation: BMC Genomics 2014 15:275
    Content type: Research article Published on:

  25. Killer Immunoglobulin-like Receptors (KIRs) are surface receptors of natural killer cells that bind to their corresponding Human Leukocyte Antigen (HLA) class I ligands, making them interesting candidate genes...

    Authors: Nikolas Pontikos, Deborah J Smyth, Helen Schuilenburg, Joanna MM Howson, Neil M Walker, Oliver S Burren, Hui Guo, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick Concannon, Stephen S Rich, Jyothi Jayaraman, Wei Jiang, James A Traherne, John Trowsdale, John A Todd…
    Citation: BMC Genomics 2014 15:274
    Content type: Research article Published on:

  26. Monitoring alien introgressions in crop plants is difficult due to the lack of genetic and molecular mapping information on the wild crop relatives. The tertiary gene pool of wheat is a very important source o...

    Authors: Vijay K Tiwari, Shichen Wang, Sunish Sehgal, Jan Vrána, Bernd Friebe, Marie Kubaláková, Praveen Chhuneja, Jaroslav Doležel, Eduard Akhunov, Bhanu Kalia, Jamal Sabir and Bikram S Gill
    Citation: BMC Genomics 2014 15:273
    Content type: Research article Published on:

  27. Within the genus Streptococcus, only Streptococcus thermophilus is used as a starter culture in food fermentations. Streptococcus macedonicus though, which belongs to the Streptococcus bovis/Streptococcus equinus

    Authors: Konstantinos Papadimitriou, Rania Anastasiou, Eleni Mavrogonatou, Jochen Blom, Nikos C Papandreou, Stavros J Hamodrakas, Stéphanie Ferreira, Pierre Renault, Philip Supply, Bruno Pot and Effie Tsakalidou
    Citation: BMC Genomics 2014 15:272
    Content type: Research article Published on:

  28. Soybean (Glycine max L.) is one of the world’s most important leguminous crops producing high-quality protein and oil. Increasing the relative oil concentration in soybean seeds is many researchers’ goal, but a c...

    Authors: Juan Yu, Zhenhai Zhang, Jiangang Wei, Yi Ling, Wenying Xu and Zhen Su
    Citation: BMC Genomics 2014 15:271
    Content type: Database Published on:

  29. Leprosy has afflicted humankind throughout history leaving evidence in both early texts and the archaeological record. In Britain, leprosy was widespread throughout the Middle Ages until its gradual and unexpl...

    Authors: Tom A Mendum, Verena J Schuenemann, Simon Roffey, G Michael Taylor, Huihai Wu, Pushpendra Singh, Katie Tucker, Jason Hinds, Stewart T Cole, Andrzej M Kierzek, Kay Nieselt, Johannes Krause and Graham R Stewart
    Citation: BMC Genomics 2014 15:270
    Content type: Research article Published on:

  30. Recently it has been shown that Ensifer adhaerens can be used as a plant transformation technology, transferring genes into several plant genomes when equipped with a Ti plasmid. For this study, we have sequenced...

    Authors: Steven Rudder, Fiona Doohan, Christopher J Creevey, Toni Wendt and Ewen Mullins
    Citation: BMC Genomics 2014 15:268
    Content type: Research article Published on:

  31. The Manila clam (Ruditapes philippinarum) is a cultured bivalve with worldwide commercial importance, and diseases cause high economic losses. For this reason, interest in the immune genes in this species has rec...

    Authors: Rebeca Moreira, Massimo Milan, Pablo Balseiro, Alejandro Romero, Massimiliano Babbucci, Antonio Figueras, Luca Bargelloni and Beatriz Novoa
    Citation: BMC Genomics 2014 15:267
    Content type: Research article Published on:

  32. Starvation not only affects the nutritional and health status of the animals, but also the microbial composition in the host’s intestine. Next-generation sequencing provides a unique opportunity to explore gut...

    Authors: Jun Hong Xia, Grace Lin, Gui Hong Fu, Zi Yi Wan, May Lee, Le Wang, Xiao Jun Liu and Gen Hua Yue
    Citation: BMC Genomics 2014 15:266
    Content type: Research article Published on:

  33. The data released by the 1000 Genomes Project contain an increasing number of genome sequences from different nations and populations with a large number of genetic variations. As a result, the focus of human ...

    Authors: Yunchao Ling, Zhong Jin, Mingming Su, Jun Zhong, Yongbing Zhao, Jun Yu, Jiayan Wu and Jingfa Xiao
    Citation: BMC Genomics 2014 15:265
    Content type: Database Published on:

  34. The rapid evolution in high-throughput sequencing (HTS) technologies has opened up new perspectives in several research fields and led to the production of large volumes of sequence data. A fundamental step in...

    Authors: Ségolène Caboche, Christophe Audebert, Yves Lemoine and David Hot
    Citation: BMC Genomics 2014 15:264
    Content type: Research article Published on:

  35. Copper is essential for the survival of aerobic organisms. If copper is not properly regulated in the body however, it can be extremely cytotoxic and genetic mutations that compromise copper homeostasis result...

    Authors: Ulrich Schlecht, Sundari Suresh, Weihong Xu, Ana Maria Aparicio, Angela Chu, Michael J Proctor, Ronald W Davis, Curt Scharfe and Robert P St Onge
    Citation: BMC Genomics 2014 15:263
    Content type: Research article Published on:

  36. Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has t...

    Authors: Jeffrey M Kidd, Thomas J Sharpton, Dean Bobo, Paul J Norman, Alicia R Martin, Meredith L Carpenter, Martin Sikora, Christopher R Gignoux, Neda Nemat-Gorgani, Alexandra Adams, Moraima Guadalupe, Xiaosen Guo, Qiang Feng, Yingrui Li, Xiao Liu, Peter Parham…
    Citation: BMC Genomics 2014 15:262
    Content type: Research article Published on:

  37. Apple tree breeding is slow and difficult due to long generation times, self-incompatibility, and complex genetics. The identification of molecular markers linked to traits of interest is a way to expedite the...

    Authors: Philip J Jensen, Gennaro Fazio, Naomi Altman, Craig Praul and Timothy W McNellis
    Citation: BMC Genomics 2014 15:261
    Content type: Research article Published on:

  38. Enzymes of the cellulose synthase (CesA) family and CesA-like (Csl) families are responsible for the synthesis of celluloses and hemicelluloses, and thus are of great interest to bioenergy research. We studied...

    Authors: Yanbin Yin, Mitrick A Johns, Huansheng Cao and Manju Rupani
    Citation: BMC Genomics 2014 15:260
    Content type: Research article Published on:

  39. Equine recurrent laryngeal neuropathy (RLN) is a bilateral mononeuropathy with an unknown pathogenesis that significantly affects performance in Thoroughbreds. A genetic contribution to the pathogenesis of RLN...

    Authors: Adam R Boyko, Samantha A Brooks, Ashley Behan-Braman, Marta Castelhano, Elizabeth Corey, Kyle C Oliveira, June E Swinburne, Rory J Todhunter, Zhiwu Zhang, Dorothy M Ainsworth and Norman Edward Robinson
    Citation: BMC Genomics 2014 15:259
    Content type: Research article Published on:

  40. The Polima (pol) system of cytoplasmic male sterility (CMS) and its fertility restoration gene Rfp have been used in hybrid breeding in Brassica napus, which has greatly improved the yield of rapeseed. However, t...

    Authors: Hong An, Zonghui Yang, Bin Yi, Jing Wen, Jinxiong Shen, Jinxing Tu, Chaozhi Ma and Tingdong Fu
    Citation: BMC Genomics 2014 15:258
    Content type: Research article Published on:

  41. Although our microbial community and genomes (the human microbiome) outnumber our genome by several orders of magnitude, to what extent the human host genetic complement informs the microbiota composition is n...

    Authors: Jun Ma, Cristian Coarfa, Xiang Qin, Penelope E Bonnen, Aleksandar Milosavljevic, James Versalovic and Kjersti Aagaard
    Citation: BMC Genomics 2014 15:257
    Content type: Research article Published on:

  42. Identifying the genotypes underlying human disease phenotypes is a fundamental step in human genetics and medicine. High-throughput genomic technologies provide thousands of genetic variants per individual. Th...

    Authors: Yuval Itan, Mark Mazel, Benjamin Mazel, Avinash Abhyankar, Patrick Nitschke, Lluis Quintana-Murci, Stephanie Boisson-Dupuis, Bertrand Boisson, Laurent Abel, Shen-Ying Zhang and Jean-Laurent Casanova
    Citation: BMC Genomics 2014 15:256
    Content type: Software Published on:

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BMC Genomics

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