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6355 result(s) for 'general transcription factors vs specific' within BMC Genomics

Page 24 of 128

  1. Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are thought to play important roles in embryonic development in mice, and several developmental defects are associated with epigenetic modificati...

    Authors: Fengrui Wu, Yong Liu, Qingqing Wu, Dengkun Li, Ling Zhang, Xiaoqing Wu, Rong Wang, Di Zhang, Shaorong Gao and Wenyong Li
    Citation: BMC Genomics 2018 19:631
    Content type: Database Published on:

  2. With 9730 protein-coding genes and a nearly complete gene knockout strain collection, Neurospora crassa is a major model organism for filamentous fungi. Despite this abundance of information, the phenotypes of th...

    Authors: Alexander J. Carrillo, Ilva E. Cabrera, Marko J. Spasojevic, Patrick Schacht, Jason E. Stajich and Katherine A. Borkovich
    Citation: BMC Genomics 2020 21:755
    Content type: Research article Published on:

  3. Hop (Humulus lupulus L.) is an economically important plant forming organogenic nodules which can be used for genetic transformation and micropropagation. We are interested in the mechanisms underlying reprogramm...

    Authors: Ana M Fortes, Filipa Santos, Young H Choi, Marta S Silva, Andreia Figueiredo, Lisete Sousa, Fernando Pessoa, Bartolomeu A Santos, Mónica Sebastiana, Klaus Palme, Rui Malhó, Rob Verpoorte and Maria S Pais
    Citation: BMC Genomics 2008 9:445
    Content type: Research article Published on:

  4. Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in fertility rates among indivi...

    Authors: Huiyan Hu, Qing Jia, Jianzhong Xi, Bo Zhou and Zhiqiang Li
    Citation: BMC Genomics 2020 21:636
    Content type: Research article Published on:

  5. The free-living nematode Caenorhabditis elegans makes a developmental decision based on environmental conditions: larvae either arrest as dauer larva, or continue development into reproductive adults. There is na...

    Authors: Simon C Harvey, Gary LA Barker, Alison Shorto and Mark E Viney
    Citation: BMC Genomics 2009 10:325
    Content type: Research article Published on:

  6. Litchi (Litchi chinensis Sonn.) is an economically important evergreen fruit tree widely cultivated in subtropical areas. Low temperature is absolutely required for floral induction of litchi, but its molecular m...

    Authors: Hongna Zhang, Jiyuan Shen, Yongzan Wei and Houbin Chen
    Citation: BMC Genomics 2017 18:363
    Content type: Research article Published on:

  7. SOX2 is a key gene implicated in maintaining the stemness of embryonic and adult stem cells. SOX2 appears to re-activate in several human cancers including glioblastoma multiforme (GBM), however, the detailed res...

    Authors: Xuefeng Fang, Jae-Geun Yoon, Lisha Li, Wei Yu, Jiaofang Shao, Dasong Hua, Shu Zheng, Leroy Hood, David R Goodlett, Gregory Foltz and Biaoyang Lin
    Citation: BMC Genomics 2011 12:11
    Content type: Research article Published on:

  8. Toxoplasma gondii is a protozoan parasite that differentiates from acute tachyzoite stages to latent bradyzoite forms in response to environmental cues that modify the epigenome. We studied the distribution of th...

    Authors: Sheila C. Nardelli, Natalie C. Silmon de Monerri, Laura Vanagas, Xiaonan Wang, Zoi Tampaki, William J. Sullivan Jr, Sergio O. Angel and Kami Kim
    Citation: BMC Genomics 2022 23:128
    Content type: Research article Published on:

  10. Estrogens are known to regulate the proliferation of breast cancer cells and to modify their phenotypic properties. Identification of estrogen-regulated genes in human breast tumors is an essential step toward...

    Authors: Martín C Abba, Yuhui Hu, Hongxia Sun, Jeffrey A Drake, Sally Gaddis, Keith Baggerly, Aysegul Sahin and C Marcelo Aldaz
    Citation: BMC Genomics 2005 6:37
    Content type: Research article Published on:

  11. A reciprocal relationship between bone and fat development in osteoporosis is clinically well established. Some of the key molecular regulators involved in this tissue replacement process have been identified....

    Authors: Marcel Scheideler, Christian Elabd, Laure-Emmanuelle Zaragosi, Chiara Chiellini, Hubert Hackl, Fatima Sanchez-Cabo, Sunaina Yadav, Kalina Duszka, Gerald Friedl, Christine Papak, Andreas Prokesch, Reinhard Windhager, Gerard Ailhaud, Christian Dani, Ez-Zoubir Amri and Zlatko Trajanoski
    Citation: BMC Genomics 2008 9:340
    Content type: Research article Published on:

  12. Mammalian testis is a highly complex and heterogeneous tissue. This complexity, which mostly derives from spermatogenic cells, is reflected at the transcriptional level, with the largest number of tissue-speci...

    Authors: Carlos Romeo-Cardeillac, María Fernanda Trovero, Santiago Radío, Pablo Smircich, Rosana Rodríguez-Casuriaga, Adriana Geisinger and José Sotelo-Silveira
    Citation: BMC Genomics 2024 25:295
    Content type: Research Published on:

  13. Recent advances in sequencing technologies have enabled parallel assays of chromatin accessibility and gene expression for major human cell lines. Such innovation provides a great opportunity to decode phenoty...

    Authors: Shining Ma, Tao Jiang and Rui Jiang
    Citation: BMC Genomics 2018 19(Suppl 10):884
    Content type: Research Published on:

    This article is part of a Supplement: Volume 19 Supplement 10

  14. Fargesia macclureana (Poaceae) is a woody bamboo species found on the Qinghai–Tibet Plateau (QTP) approximately 2000 ~ 3800 m above sea level. It rarely blossoms in the QTP, but it flowered 20 days after growing ...

    Authors: Ying Li, Chunxia Zhang, Kebin Yang, Jingjing Shi, Yulong Ding and Zhimin Gao
    Citation: BMC Genomics 2019 20:1035
    Content type: Research article Published on:

  15. The rose is one of the most important ornamental flowers in the world for its aesthetic beauty but can be attacked by many pests such as aphids. Aphid infestation causes tremendous damage on plant tissues lead...

    Authors: Wenqi Dong, Lei Sun, Bo Jiao, Pu Zhao, Chunhong Ma, Junping Gao and Shuo Zhou
    Citation: BMC Genomics 2024 25:232
    Content type: Research Published on:

  16. Microglia are multifunctional cells that are key players in brain development and homeostasis. Recent years have seen tremendous growth in our understanding of the role microglia play in neurodegeneration, CNS...

    Authors: Christine E. Cho, Sagar S. Damle, Edward V. Wancewicz, Swagatam Mukhopadhyay, Christopher E. Hart, Curt Mazur, Eric E. Swayze and Fredrik Kamme
    Citation: BMC Genomics 2019 20:164
    Content type: Research article Published on:

  17. Complementary single-nucleotide polymorphisms (SNPs) may not be distributed equally between two DNA strands if the strands are functionally distinct, such as in transcribed genes. In introns, an excess of A↔G ...

    Authors: Hui-Qi Qu, Steve G Lawrence, Fan Guo, Jacek Majewski and Constantin Polychronakos
    Citation: BMC Genomics 2006 7:213
    Content type: Research article Published on:

  18. During embryogenesis, the developmental potential of initially pluripotent cells becomes progressively restricted as they transit to lineage restricted states. The pluripotent cells of Xenopus blastula-stage embr...

    Authors: Kristin Johnson, Simon Freedman, Rosemary Braun and Carole LaBonne
    Citation: BMC Genomics 2022 23:723
    Content type: Research Published on:

  19. Excessive accumulation of adipose tissue in cultured fish is an outstanding problem in aquaculture. To understand the development of adiposity, it is crucial to identify the genes which expression is associate...

    Authors: Marta Bou, Jerôme Montfort, Aurélie Le Cam, Cécile Rallière, Véronique Lebret, Jean-Charles Gabillard, Claudine Weil, Joaquim Gutiérrez, Pierre-Yves Rescan, Encarnación Capilla and Isabel Navarro
    Citation: BMC Genomics 2017 18:347
    Content type: Research article Published on:

  20. The emergence of high throughput genome sequencing facilities and powerful high performance bioinformatic tools has highlighted hitherto unexpected wide occurrence of globins in the three kingdoms of life. In sil...

    Authors: David Hoogewijs, Eva Geuens, Sylvia Dewilde, Andy Vierstraete, Luc Moens, Serge Vinogradov and Jacques R Vanfleteren
    Citation: BMC Genomics 2007 8:356
    Content type: Research article Published on:

  22. Genic male sterility (GMS) line is an important approach to utilize heterosis in Brassica rapa, one of the most widely cultivated vegetable crops in Northeast Asia. However, the molecular genetic mechanisms of GM...

    Authors: Xiuping Shen, Liai Xu, Yanhong Liu, Heng Dong, Dong Zhou, Yuzhi Zhang, Sue Lin, Jiashu Cao and Li Huang
    Citation: BMC Genomics 2019 20:264
    Content type: Research article Published on:

  23. European foulbrood is a significant bacterial brood disease of Apis sp. and can cause severe and devastating damages in beekeeping operations. Nevertheless, the epidemiology of its causative agent Melissococcus p...

    Authors: Oleg Lewkowski, Anja Poehlein, Rolf Daniel and Silvio Erler
    Citation: BMC Genomics 2022 23:837
    Content type: Research Published on:

  24. Blood feeding, or hematophagy, is a behavior exhibited by female mosquitoes required both for reproduction and for transmission of pathogens. We determined the expression patterns of 3,068 ESTs, representing ~...

    Authors: Ali N Dana, Young S Hong, Marcia K Kern, Maureen E Hillenmeyer, Brent W Harker, Neil F Lobo, James R Hogan, Patricia Romans and Frank H Collins
    Citation: BMC Genomics 2005 6:5
    Content type: Research article Published on:

  25. Bean pyralid is one of the major leaf-feeding insects that affect soybean crops. DNA methylation can control the networks of gene expressions, and it plays an important role in responses to biotic stress. Howe...

    Authors: Wei-Ying Zeng, Yu-Rong Tan, Sheng-Feng Long, Zu-Dong Sun, Zhen-Guang Lai, Shou-Zhen Yang, Huai-Zhu Chen and Xia-Yan Qing
    Citation: BMC Genomics 2021 22:836
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2021 22:913

  26. Daphnia species reproduce by cyclic parthenogenesis involving both sexual and asexual reproduction. The sex of the offspring is environmentally determined and mediated via endocrine signalling by the mother. Inte...

    Authors: Jouni Kvist, Camila Gonçalves Athanàsio, Michael E. Pfrender, James B. Brown, John K. Colbourne and Leda Mirbahai
    Citation: BMC Genomics 2020 21:17
    Content type: Research article Published on:

  27. Gaucher disease is caused by defective glucocerebrosidase activity and the consequent accumulation of glucosylceramide. The pathogenic pathways resulting from lipid laden macrophages (Gaucher cells) in viscera...

    Authors: You-Hai Xu, Li Jia, Brian Quinn, Matthew Zamzow, Keith Stringer, Bruce Aronow, Ying Sun, Wujuan Zhang, Kenneth DR Setchell and Gregory A Grabowski
    Citation: BMC Genomics 2011 12:20
    Content type: Research article Published on:

  28. Accumulating evidence suggests an important role for the enzyme poly(ADP-ribose) polymerase-1 (PARP-1) as an integral part of the gene expression regulatory machinery during development and in response to spec...

    Authors: Luis Saenz, Juan J Lozano, Rut Valdor, Alberto Baroja-Mazo, Pablo Ramirez, Pascual Parrilla, Pedro Aparicio, Lauro Sumoy and José Yélamos
    Citation: BMC Genomics 2008 9:171
    Content type: Research article Published on:

  29. Previous studies show that galanin neurons in ventrolateral preoptic nucleus (VLPO-Gal) are essential for sleep regulation. Here, we explored the transcriptional regulation of the VLPO-Gal neurons in sleep by ...

    Authors: Xiaofeng Guo, Xiaoling Gao, Brendan T. Keenan, Jingxu Zhu, Dimitra Sarantopoulou, Jie Lian, Raymond J. Galante, Gregory R. Grant and Allan I. Pack
    Citation: BMC Genomics 2020 21:633
    Content type: Research article Published on:

  30. Globoid cell leukodystrophy (GLD) is a devastating neurodegenerative disease characterized by widespread demyelination caused by galactocerebrosidase defects. Changes in GLD pathogenesis occurring at the molec...

    Authors: Yafeng Lv, Yu Qin, Jing Wang, Guoshuai Tian, Wei Wang, Chunyu Cao and Ye Zhang
    Citation: BMC Genomics 2023 24:210
    Content type: Research Published on:

  31. Computational identification of non-coding RNAs (ncRNAs) is a challenging problem. We describe a genome-wide analysis using Bayesian segmentation to identify intronic elements highly conserved between three ev...

    Authors: Manjula Algama, Edward Tasker, Caitlin Williams, Adam C. Parslow, Robert J. Bryson-Richardson and Jonathan M. Keith
    Citation: BMC Genomics 2017 18:259
    Content type: Research article Published on:

  32. Brain-derived neurotrophic factor (BDNF) is a major signaling molecule that the brain uses to control a vast network of intracellular cascades fundamental to properties of learning and memory, and cognition. W...

    Authors: Kathryn M. Hixson, Meaghan Cogswell, Amy R. Brooks-Kayal and Shelley J. Russek
    Citation: BMC Genomics 2019 20:677
    Content type: Research article Published on:

  33. Bacterial genomes displaying a strong bias between the leading and the lagging strand of DNA replication encode two DNA polymerases III, DnaE and PolC, rather than a single one. Replication is a highly unsymme...

    Authors: Stefan Engelen, David Vallenet, Claudine Médigue and Antoine Danchin
    Citation: BMC Genomics 2012 13:69
    Content type: Research article Published on:

  34. The nervous system is central to coordinating behavioural responses to environmental change, likely including ocean acidification (OA). However, a clear understanding of neurobiological responses to OA is lack...

    Authors: Jodi T. Thomas, Roger Huerlimann, Celia Schunter, Sue-Ann Watson, Philip L. Munday and Timothy Ravasi
    Citation: BMC Genomics 2024 25:635
    Content type: Research Published on:

  35. Isolates of Serratia entomophila and S. proteamaculans (Yersiniaceae) cause disease specific to the endemic New Zealand pasture pest, Costelytra giveni (Coleoptera: Scarabaeidae). Previous genomic profiling has s...

    Authors: Amy L. Vaughan, Eric Altermann, Travis R. Glare and Mark R. H. Hurst
    Citation: BMC Genomics 2022 23:728
    Content type: Research Published on:

  36. Despite numerous studies suggesting that amphibians are highly sensitive to cumulative anthropogenic stresses, the role pollutants play in the decline of amphibian populations remains unclear. Amongst the most...

    Authors: Christophe Regnault, Isabelle AM Worms, Christine Oger-Desfeux, Christelle MelodeLima, Sylvie Veyrenc, Marie-Laure Bayle, Bruno Combourieu, Aurélie Bonin, Julien Renaud, Muriel Raveton and Stéphane Reynaud
    Citation: BMC Genomics 2014 15:666
    Content type: Research article Published on:

  37. MicroRNAs are non-coding RNAs that regulate gene expression including differentiation and development by either inhibiting translation or inducing target degradation. The aim of this study is to determine the ...

    Authors: Samuel Rosero, Valia Bravo-Egana, Zhijie Jiang, Sawsan Khuri, Nicholas Tsinoremas, Dagmar Klein, Eduardo Sabates, Mayrin Correa-Medina, Camillo Ricordi, Juan Domínguez-Bendala, Juan Diez and Ricardo L Pastori
    Citation: BMC Genomics 2010 11:509
    Content type: Research article Published on:

  38. Jasmonate-ZIM domain (JAZ) repressors negatively regulate signal transduction of jasmonates, which regulate plant development and immunity. However, no comprehensive analysis of the JAZ gene family members has be...

    Authors: Miaoyu Song, Haomiao Wang, Huiqin Ma and Chuanlin Zheng
    Citation: BMC Genomics 2022 23:170
    Content type: Research Published on:

  39. Cold storage induces chilling injury (CI) disorders in peach fruit (woolliness/mealiness, flesh browning and reddening/bleeding) manifested when ripened at shelf life. To gain insight into the mechanisms under...

    Authors: Clara Pons Puig, Anurag Dagar, Cristina Marti Ibanez, Vikram Singh, Carlos H Crisosto, Haya Friedman, Susan Lurie and Antonio Granell
    Citation: BMC Genomics 2015 16:245
    Content type: Research article Published on:

  40. Flavonols are the largest subgroup of flavonoids, possessing multiple functions in plants including protection against ultraviolet radiation, antimicrobial activities, and flower pigmentation together with ant...

    Authors: Hanna M. Schilbert and Beverley J. Glover
    Citation: BMC Genomics 2022 23:604
    Content type: Research Published on:

  41. Long non-coding RNAs (lncRNAs) are involved in several immune processes, including the immune response to vaccination, but most of them remain uncharacterised in livestock species. The mechanism of action of a...

    Authors: Martin Bilbao-Arribas, Endika Varela-Martínez, Naiara Abendaño, Damián de Andrés, Lluís Luján and Begoña M. Jugo
    Citation: BMC Genomics 2021 22:770
    Content type: Research Published on:

  42. Environmental stress factors, such as biotic and abiotic stress, are becoming more common due to climate variability, significantly affecting global maize yield. Transcriptome profiling studies provide insight...

    Authors: Rita K Hayford, Olivia C Haley, Ethalinda K Cannon, John L Portwood II, Jack M Gardiner, Carson M Andorf and Margaret R Woodhouse
    Citation: BMC Genomics 2024 25:533
    Content type: Research Published on:

  43. The aneurysm clip impact-compression model of spinal cord injury (SCI) is a standard injury model in animals that closely mimics the primary mechanism of most human injuries: acute impact and persisting compre...

    Authors: Mahmood Chamankhah, Eftekhar Eftekharpour, Soheila Karimi-Abdolrezaee, Paul C Boutros, Serban San-Marina and Michael G Fehlings
    Citation: BMC Genomics 2013 14:583
    Content type: Research article Published on:

  44. Streptococcus pneumoniae is a leading cause of childhood morbidity and mortality worldwide, despite the availability of effective pneumococcal vaccines. Understanding the molecular interactions between the bacter...

    Authors: Sheila Z Kimaro Mlacha, Sandra Romero-Steiner, Julie C Dunning Hotopp, Nikhil Kumar, Nadeeza Ishmael, David R Riley, Umar Farooq, Todd H Creasy, Luke J Tallon, Xinyue Liu, Cynthia S Goldsmith, Jacquelyn Sampson, George M Carlone, Susan K Hollingshead, J Anthony G Scott and Hervé Tettelin
    Citation: BMC Genomics 2013 14:383
    Content type: Research article Published on:

  45. Seeds are the economic basis of oilseed crops, especially soybeans, the most widely cultivated oilseed crop worldwide. Seed development is accompanied by a multitude of diverse cellular processes, and revealin...

    Authors: Hengyou Zhang, Zhenbin Hu, Yuming Yang, Xiaoqian Liu, Haiyan Lv, Bao-Hua Song, Yong-qiang Charles An, Zhimin Li and Dan Zhang
    Citation: BMC Genomics 2021 22:453
    Content type: Research article Published on:

  46. Acute quadriplegic myopathy (AQM) or critical illness myopathy (CIM) is frequently observed in intensive care unit (ICU) patients. To elucidate duration-dependent effects of the ICU intervention on molecular a...

    Authors: Monica Llano-Diez, Ann-Marie Gustafson, Carl Olsson, Hanna Goransson and Lars Larsson
    Citation: BMC Genomics 2011 12:602
    Content type: Research article Published on:

  47. CRISPR/Cas9-mediated transcriptional interference (CRISPRi) enables programmable gene knock-down, yielding loss-of-function phenotypes for nearly any gene. Effective, inducible CRISPRi has been demonstrated in...

    Authors: Nicholas J. McGlincy, Zuriah A. Meacham, Kendra K. Reynaud, Ryan Muller, Rachel Baum and Nicholas T. Ingolia
    Citation: BMC Genomics 2021 22:205
    Content type: Methodology article Published on:

  48. Color patterns in angiosperm flowers are produced by spatially and temporally restricted deposition of pigments. Identifying the mechanisms responsible for restricted pigment deposition is a topic of broad int...

    Authors: Kazuma Suzuki, Tomohiro Suzuki, Takashi Nakatsuka, Hideo Dohra, Masumi Yamagishi, Kohei Matsuyama and Hideyuki Matsuura
    Citation: BMC Genomics 2016 17:611
    Content type: Research article Published on:

  49. The SROs (SIMILAR TO RCD-ONE) are a group of plant-specific proteins which have important functions in stress adaptation and development. They contain the catalytic core of the poly(ADP-ribose) polymerase (PAR...

    Authors: Pinja Jaspers, Kirk Overmyer, Michael Wrzaczek, Julia P Vainonen, Tiina Blomster, Jarkko Salojärvi, Ramesha A Reddy and Jaakko Kangasjärvi
    Citation: BMC Genomics 2010 11:170
    Content type: Research article Published on:

  50. Methylotrophic yeast species (e.g. Hansenula polymorpha, Pichia pastoris) can grow on methanol as sole source of carbon and energy. These organisms are important cell factories for the production of recombinant p...

    Authors: Tim van Zutphen, Richard JS Baerends, Kim A Susanna, Anne de Jong, Oscar P Kuipers, Marten Veenhuis and Ida J van der Klei
    Citation: BMC Genomics 2010 11:1
    Content type: Research article Published on:

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BMC Genomics

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