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  1. Advances in DNA sequencing technologies have transformed our capacity to perform life science research, decipher the dynamics of complex soil microbial communities and exploit them for plant disease management...

    Authors: Guoshun Xu, Liwen Zhang, Xiaoqing Liu, Feifei Guan, Yuquan Xu, Haitao Yue, Jin-Qun Huang, Jieyin Chen, Ningfeng Wu and Jian Tian
    Citation: BMC Genomics 2022 23:37
  2. Bioassessment and biomonitoring of meat products are aimed at identifying and quantifying adulterants and contaminants, such as meat from unexpected sources and microbes. Several methods for determining the bi...

    Authors: Mei Jiang, Shu-Fei Xu, Tai-Shan Tang, Li Miao, Bao-Zheng Luo, Yang Ni, Fan-De Kong and Chang Liu
    Citation: BMC Genomics 2022 23:36
  3. The composition of intramuscular fat depends on genetic and environmental factors, including the diet. In pigs, we identified a haplotype of three SNP mutations in the stearoyl-coA desaturase (SCD) gene promoter ...

    Authors: Emma Solé, Rayner González-Prendes, Yelyzaveta Oliinychenko, Marc Tor, Roger Ros-Freixedes, Joan Estany and Ramona N. Pena
    Citation: BMC Genomics 2022 23:16
  4. Interferon regulatory factor-8 (IRF8) and nuclear factor-activated T cells c1 (NFATc1) are two transcription factors that have an important role in osteoclast differentiation. Thanks to ChIP-seq technology, sc...

    Authors: Honglin Wang, Pujan Joshi, Seung-Hyun Hong, Peter F. Maye, David W. Rowe and Dong-Guk Shin
    Citation: BMC Genomics 2022 23:14
  5. Brassinosteroids (BRs) are a type of sterol plant hormone that play an important role in various biochemical and physiological reactions such as promoting cell growth, increasing biomass, and improving stress ...

    Authors: Qifang Jin, Zhong Wang, Yanni Chen, Yiping Luo, Na Tian, Zhonghua Liu, Jianan Huang and Shuoqian Liu
    Citation: BMC Genomics 2022 23:29
  6. Histone deacetylases (HDACs) play an important role in the regulation of gene expression, which is indispensable in plant growth, development, and responses to environmental stresses. In Arabidopsis and rice, the...

    Authors: Qiaoli Du, Yuanpeng Fang, Junmei Jiang, Meiqing Chen, Xiaodong Fu, Zaifu Yang, Liting Luo, Qijiao Wu, Qian Yang, Lujie Wang, Zhiguang Qu, Xiangyang Li and Xin Xie
    Citation: BMC Genomics 2022 23:28
  7. Handeliodendron Rehder and Eurycorymbus Hand.-Mazz. are the monotypic genera in the Sapindaceae family. The phylogenetic relationship of these endangered species Handeliodendron bodinieri (Lévl.) Rehd. and Euryc...

    Authors: Jiaxin Yang, Guoxiong Hu and Guangwan Hu
    Citation: BMC Genomics 2022 23:27
  8. Valgus-varus deformity (VVD) is a lateral or middle deviation of the tibiotarsus or tarsometatarsus, which is associated with compromised growth, worse bone quality and abnormal changes in serum indicators in ...

    Authors: Yaping Guo, Hetian Huang, Zhenzhen Zhang, Yanchao Ma, Jianzeng Li, Hehe Tang, Haoxiang Ma, Zhuanjian Li, Wenting Li, Xiaojun Liu, Xiangtao Kang and Ruili Han
    Citation: BMC Genomics 2022 23:26
  9. Migration of neuroblasts and neurons from their birthplace is central to the formation of neural circuits and networks. ETR-1 is the Caenorhabditis elegans homolog of the CELF1 (CUGBP, ELAV-like family 1) RNA-pro...

    Authors: Matthew E. Ochs, Rebecca M. McWhirter, Robert L. Unckless, David M. Miller III and Erik A. Lundquist
    Citation: BMC Genomics 2022 23:13
  10. Zebrafish have practical features that make them a useful model for higher-throughput tests of gene function using CRISPR/Cas9 editing to create ‘knockout’ models. In particular, the use of G0 mosaic mutants has ...

    Authors: José M. Uribe-Salazar, Gulhan Kaya, Aadithya Sekar, KaeChandra Weyenberg, Cole Ingamells and Megan Y. Dennis
    Citation: BMC Genomics 2022 23:12
  11. Neonicotinoids are widely applied in the control of the destructive agricultural pest Bemisia tabaci, and resistance against these chemicals has become a common, severe problem in the control of whiteflies. To in...

    Authors: Cheng Song Zhou, Huan Huan Lv, Xiao Hu Guo, Qian Cao, Rui Xingyue Zhang and De Ying Ma
    Citation: BMC Genomics 2022 23:15
  12. Oil palm (Elaeis guineensis, Jacq.) is an important vegetable oil-yielding plant. Somatic embryogenesis is a promising method to produce large-scale elite clones to meet the demand for palm oil. The epigenetic me...

    Authors: Lixia Zhou, Rajesh Yarra, Longfei Jin, Yaodong Yang, Hongxing Cao and Zhihao Zhao
    Citation: BMC Genomics 2022 23:11
  13. The pistil is an essential part of flowers that functions in the differentiation of the sexes and reproduction in plants. The stigma on the pistil can accept pollen to allow fertilization and seed development....

    Authors: Zhenyang Liao, Fei Dong, Juan Liu, Lele Xu, Amy Marshall-Colon and Ray Ming
    Citation: BMC Genomics 2022 23:8
  14. Aspergillus flavus, one of the causative agents of human fungal keratitis, can be phagocytosed by human corneal epithelial (HCE) cells and the conidia containing phagosomes mature into phagolysosomes. But the imm...

    Authors: Divya Arunachalam, Shruthi Mahalakshmi Ramanathan, Athul Menon, Lekshmi Madhav, Gopalakrishna Ramaswamy, Venkatesh Prajna Namperumalsamy, Lalitha Prajna and Dharmalingam Kuppamuthu
    Citation: BMC Genomics 2022 23:5
  15. In the nematode Caenorhabditis elegans, longevity in response to germline ablation, but not in response to reduced insulin/IGF1-like signaling, is strongly dependent on the conserved protein kinase minibrain-rela...

    Authors: Hildegard I. D. Mack, Jennifer Kremer, Eva Albertini, Elisabeth K. M. Mack and Pidder Jansen-Dürr
    Citation: BMC Genomics 2022 23:25
  16. Authors: Sofa A. Bengoa Luoni, Alberto Cenci, Sebastian Moschen, Salvador Nicosia, Laura M. Radonic, Julia V. Sabio y García, Nicolas B. Langlade, Denis Vile, Cecilia Vazquez Rovere and Paula Fernandez
    Citation: BMC Genomics 2022 23:24

    The original article was published in BMC Genomics 2021 22:893

  17. South Africa and Australia shares multiple important sheep breeds. For some of these breeds, genomic breeding values are provided to breeders in Australia, but not yet in South Africa. Combining genomic resour...

    Authors: Cornelius Nel, Phillip Gurman, Andrew Swan, Julius van der Werf, Margaretha Snyman, Kennedy Dzama, Klint Gore, Anna Scholtz and Schalk Cloete
    Citation: BMC Genomics 2022 23:23
  18. Circular RNAs (circRNAs) are a group of noncoding RNAs that participate in gene expression regulation in various pathways. The essential roles of circRNAs have been revealed in many species. However, knowledge...

    Authors: Xingwei Cao, Xingye Xu, Jie Dong, Ying Xue, Lilian Sun, Yafang Zhu, Tao Liu and Qi Jin
    Citation: BMC Genomics 2022 23:21
  19. Transposable elements (TE) make up a large portion of many plant genomes and are playing innovative roles in genome evolution. Several TEs can contribute to gene regulation by influencing expression of nearby ...

    Authors: Jan Deneweth, Yves Van de Peer and Vanessa Vermeirssen
    Citation: BMC Genomics 2022 23:18
  20. Sexual maturation causes loss of fish muscle mass and deterioration of fillet quality attributes that prevent market success. We recently showed that fillet yield and flesh quality recover in female trout afte...

    Authors: Yéléhi-Diane Ahongo, Aurélie Le Cam, Jérôme Montfort, Jérôme Bugeon, Florence Lefèvre and Pierre-Yves Rescan
    Citation: BMC Genomics 2022 23:9
  21. With the exponential growth of publicly available genome sequences, pangenome analyses have provided increasingly complete pictures of genetic diversity for many microbial species. However, relatively few stud...

    Authors: Jason C. Hyun, Jonathan M. Monk and Bernhard O. Palsson
    Citation: BMC Genomics 2022 23:7
  22. Snakes exhibit extreme intestinal regeneration following months-long fasts that involves unparalleled increases in metabolism, function, and tissue growth, but the specific molecular control of this process is...

    Authors: Aundrea K. Westfall, Blair W. Perry, Abu H. M. Kamal, Nicole R. Hales, Jarren C. Kay, Madhab Sapkota, Drew R. Schield, Mark W. Pellegrino, Stephen M. Secor, Saiful M. Chowdhury and Todd A. Castoe
    Citation: BMC Genomics 2022 23:6
  23. Grain size is a key factor in crop yield that gradually develops after pollination. However, few studies have reported gene expression patterns in maize grain development using large-grain mutants. To investig...

    Authors: Yanrong Zhang, Fuchao Jiao, Jun Li, Yuhe Pei, Meiai Zhao, Xiyun Song and Xinmei Guo
    Citation: BMC Genomics 2022 23:4
  24. Because some of its CNS neurons (e.g., retinal ganglion cells after optic nerve crush (ONC)) regenerate axons throughout life, whereas others (e.g., hindbrain neurons after spinal cord injury (SCI)) lose this cap...

    Authors: Sergei Reverdatto, Aparna Prasad, Jamie L. Belrose, Xiang Zhang, Morgan A. Sammons, Kurt M. Gibbs and Ben G. Szaro
    Citation: BMC Genomics 2022 23:2
  25. The mechanism implicated in the osteogenesis of human periodontal ligament stem cells (PDLSCs) has been investigated for years. Previous genomics data analyses showed that long noncoding RNA (lncRNA), microRNA...

    Authors: Lingzhi Lai, Zhaodan Wang, Yihong Ge, Wei Qiu, Buling Wu, Fuchun Fang, Huiyong Xu and Zhao Chen
    Citation: BMC Genomics 2022 23:1
  26. SPX-containing proteins have been known as key players in phosphate signaling and homeostasis. In Arabidopsis and rice, functions of some SPXs have been characterized, but little is known about their function ...

    Authors: Mahnaz Nezamivand-Chegini, Esmaeil Ebrahimie, Ahmad Tahmasebi, Ali Moghadam, Saeid Eshghi, Manijeh Mohammadi-Dehchesmeh, Stanislav Kopriva and Ali Niazi
    Citation: BMC Genomics 2021 22:915
  27. The yield of many crop plants can be substantially reduced by plant-pathogenic Xanthomonas bacteria. The infection strategy of many Xanthomonas strains is based on transcription activator-like effectors (TALEs), ...

    Authors: Annett Erkes, Stefanie Mücke, Maik Reschke, Jens Boch and Jan Grau
    Citation: BMC Genomics 2021 22:914
  28. The severity of influenza disease can range from mild symptoms to severe respiratory failure and can partly be explained by host genetic factors that predisposes the host to severe influenza. Here, we aimed to...

    Authors: Nina Van Goethem, Célestin Danwang, Nathalie Bossuyt, Herman Van Oyen, Nancy H. C. Roosens and Annie Robert
    Citation: BMC Genomics 2021 22:912
  29. Known as the prerequisite component for the heterosis breeding system, the male sterile line determines the hybrid yield and seed purity. Therefore, a deep understanding of the mechanism and gene network that ...

    Authors: Yong-jie Liu, Dan Li, Jie Gong, Yong-bo Wang, Zhao-bo Chen, Bin-shuang Pang, Xian-chao Chen, Jian-gang Gao, Wei-bing Yang, Feng-ting Zhang, Yi-miao Tang, Chang-ping Zhao and Shi-qing Gao
    Citation: BMC Genomics 2021 22:911
  30. Identification of epistatic interactions provides a systematic way for exploring associations among different single nucleotide polymorphism (SNP) and complex diseases. Although considerable progress has been ...

    Authors: Yu Zhong Peng, Yanmei Lin, Yiran Huang, Ying Li, Guangsheng Luo and Jianping Liao
    Citation: BMC Genomics 2021 22(Suppl 1):910

    This article is part of a Supplement: Volume 22 Supplement 1

  31. Intellectual disability (ID) can be caused by non-genetic and genetic factors, the latter being responsible for more than 1700 ID-related disorders. The broad ID phenotypic and genetic heterogeneity, as well a...

    Authors: Nuno Maia, Maria João Nabais Sá, Manuel Melo-Pires, Arjan P. M. de Brouwer and Paula Jorge
    Citation: BMC Genomics 2021 22:909
  32. Biological mutagens (such as transposon) with sequences inserted, play a crucial role to link observed phenotype and genotype in reverse genetic studies. For this reason, accurate and efficient software tools ...

    Authors: Rui Song, Ziyao Wang, Hui Wang, Han Zhang, Xuemeng Wang, Hanh Nguyen, David Holding, Bin Yu, Tom Clemente, Shangang Jia and Chi Zhang
    Citation: BMC Genomics 2021 22:908
  33. Cystic and alveolar echinococcosis caused by the tapeworms Echinococcus granulosus sensu stricto (s.s.) and E. multilocularis, respectively, are important zoonotic diseases. Protease inhibitors are crucial for...

    Authors: Hui Zhang, Mengxiao Tian, Wenjing Qi, Juan Wu, Huajun Zheng, Gang Guo, Liang Zhang, Shiwanthi L. Ranasinghe, Donald P. McManus, Jun Li and Wenbao Zhang
    Citation: BMC Genomics 2021 22:907
  34. Disruption of alveolar epithelial cell (AEC) differentiation is implicated in distal lung diseases such as chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and lung adenocarcinoma that imp...

    Authors: B. Zhou, T. R. Stueve, E. A. Mihalakakos, L. Miao, D. Mullen, Y. Wang, Y. Liu, J. Luo, E. Tran, K. D. Siegmund, S. K. Lynch, A. L. Ryan, I. A. Offringa, Z. Borok and C. N. Marconett
    Citation: BMC Genomics 2021 22:906
  35. German Black Pied cattle (DSN) are an endangered dual-purpose breed which was largely replaced by Holstein cattle due to their lower milk yield. DSN cattle are kept as a genetic reserve with a current herd siz...

    Authors: Guilherme B. Neumann, Paula Korkuć, Danny Arends, Manuel J. Wolf, Katharina May, Monika Reißmann, Salma Elzaki, Sven König and Gudrun A. Brockmann
    Citation: BMC Genomics 2021 22:905
  36. Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in the liver parenchyma and tissue remodelling. Different cell types...

    Authors: Maciej Migdał, Eugeniusz Tralle, Karim Abu Nahia, Łukasz Bugajski, Katarzyna Zofia Kędzierska, Filip Garbicz, Katarzyna Piwocka, Cecilia Lanny Winata and Michał Pawlak
    Citation: BMC Genomics 2021 22:904
  37. Myelodysplastic syndromes (MDS) are clonal disorders of hematopoietic stem cells exhibiting ineffective hematopoiesis and tendency for transformation into acute myeloid leukemia (AML). The available karyotypin...

    Authors: Nida Anwar, Faheem Ahmed Memon, Saba Shahid, Muhammad Shakeel, Muhammad Irfan, Aisha Arshad, Arshi Naz, Ikram Din Ujjan and Tahir Shamsi
    Citation: BMC Genomics 2021 22:903
  38. Sickle cell disease (SCD) is an important cause of under-five mortality. Tanzania is the 5th country in the world with the highest births prevalence of SCD individuals. Significant advances in the neonatal dia...

    Authors: Heavenlight Christopher, Adam Burns, Emmanuel Josephat, Julie Makani, Anna Schuh and Siana Nkya
    Citation: BMC Genomics 2021 22:902
  39. Satellite cells are the myogenic precursor cells in adult skeletal muscle. The objective of this study was to identify enhancers and transcription factors that regulate gene expression during the differentiati...

    Authors: Pengcheng Lyu, Robert E. Settlage and Honglin Jiang
    Citation: BMC Genomics 2021 22:901
  40. Pre-harvest sprouting (PHS) is a major problem for wheat production due to its direct detrimental effects on wheat yield, end-use quality and seed viability. Annually, PHS is estimated to cause > 1.0 billion U...

    Authors: Raman Dhariwal, Colin W. Hiebert, Mark E. Sorrells, Dean Spaner, Robert J. Graf, Jaswinder Singh and Harpinder S. Randhawa
    Citation: BMC Genomics 2021 22:900
  41. Ovarian follicle development plays an important role in determination of poultry egg production. The follicles at the various developmental stages possess their own distinct molecular genetic characteristics a...

    Authors: Xue Sun, Xiaoxia Chen, Jinghua Zhao, Chang Ma, Chunchi Yan, Simushi Liswaniso, Rifu Xu and Ning Qin
    Citation: BMC Genomics 2021 22:899
  42. Genetic and functional genomics studies require a high-quality genome assembly. Tomato (Solanum lycopersicum), an important horticultural crop, is an ideal model species for the study of fruit development.

    Authors: Xiao Su, Baoan Wang, Xiaolin Geng, Yuefan Du, Qinqin Yang, Bin Liang, Ge Meng, Qiang Gao, Wencai Yang, Yingfang Zhu and Tao Lin
    Citation: BMC Genomics 2021 22:898
  43. The general picture of human genetic variation has been vastly depicted in the last years, yet many populations remain broadly understudied. In this work, we analyze for the first time the Merchero population,...

    Authors: André Flores-Bello, Neus Font-Porterias, Julen Aizpurua-Iraola, Sara Duarri-Redondo and David Comas
    Citation: BMC Genomics 2021 22:897
  44. Mating induces behavioral and physiological changes in the arbovirus vector Aedes aegypti, including stimulation of egg development and oviposition, increased survival, and reluctance to re-mate with subsequent m...

    Authors: I. Alexandra Amaro, Yasir H. Ahmed-Braimah, Garrett P. League, Sylvie A. Pitcher, Frank W. Avila, Priscilla C. Cruz, Laura C. Harrington and Mariana F. Wolfner
    Citation: BMC Genomics 2021 22:896
  45. Authors: Kerstin Neubert, Eric Zuchantke, Robert Maximilian Leidenfrost, Röbbe Wünschiers, Josephine Grützke, Burkhard Malorny, Holger Brendebach, Sascha Al Dahouk, Timo Homeier, Helmut Hotzel, Knut Reinert, Herbert Tomaso and Anne Busch
    Citation: BMC Genomics 2021 22:895

    The original article was published in BMC Genomics 2021 22:822

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