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6358 result(s) for 'general transcription factors vs specific' within BMC Genomics

Page 71 of 128

  1. The development of essential hypertension is associated with a wide range of mechanisms. The brain stem neurons are essential for the homeostatic regulation of arterial pressure as they control baroreflex and ...

    Authors: Larisa A. Fedoseeva, Leonid O. Klimov, Nikita I. Ershov, Vadim M. Efimov, Arcady L. Markel, Yuriy L. Orlov and Olga E. Redina
    Citation: BMC Genomics 2019 20(Suppl 3):297
    Content type: Research Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  2. Parasitic nematodes, significant pathogens for humans, animals, and plants, depend on diverse organ systems for intra-host survival. Understanding the cellular diversity and molecular variations underlying the...

    Authors: Rahul Tyagi, Bruce A Rosa, Amanda Swain, Maxim N Artyomov, Douglas P Jasmer and Makedonka Mitreva
    Citation: BMC Genomics 2024 25:341
    Content type: Research Published on:

  3. The ability to localise or follow endogenous proteins in real time in vivo is of tremendous utility for cell biology or systems biology studies. Protein trap screens utilise the random genomic insertion of a tran...

    Authors: Jelena Aleksic, Ranko Lazic, Ilka Müller, Steven R Russell and Boris Adryan
    Citation: BMC Genomics 2009 10:249
    Content type: Methodology article Published on:

  4. Rhizobium tropici CIAT 899 and Rhizobium sp. PRF 81 are α-Proteobacteria that establish nitrogen-fixing symbioses with a range of legume hosts. These strains are broadly used in commercial inoculants for applicat...

    Authors: Ernesto Ormeño-Orrillo, Pâmela Menna, Luiz Gonzaga P Almeida, Francisco Javier Ollero, Marisa Fabiana Nicolás, Elisete Pains Rodrigues, Andre Shigueyoshi Nakatani, Jesiane Stefânia Silva Batista, Ligia Maria Oliveira Chueire, Rangel Celso Souza, Ana Tereza Ribeiro Vasconcelos, Manuel Megías, Mariangela Hungria and Esperanza Martínez-Romero
    Citation: BMC Genomics 2012 13:735
    Content type: Research article Published on:

  5. Typhoid fever is an infectious disease of global importance that is caused by Salmonella enterica subsp. enterica serovar Typhi (S. Typhi). This disease causes an estimated 200,000 deaths per year and remains a s...

    Authors: Kien-Pong Yap, Han Ming Gan, Cindy Shuan Ju Teh, Lay Ching Chai and Kwai Lin Thong
    Citation: BMC Genomics 2014 15:1007
    Content type: Research article Published on:

  6. Macrophages play essential roles in both innate and adaptive immune responses. Bacteria require endotoxin, a complex lipopolysaccharide, for outer membrane permeability and the host interprets endotoxin as a s...

    Authors: Ceren Ciraci, Christopher K Tuggle, Michael J Wannemuehler, Dan Nettleton and Susan J Lamont
    Citation: BMC Genomics 2010 11:545
    Content type: Research article Published on:

  7. Transcriptome analysis in combination with pathway-focused bioassays is suggested to be a helpful approach for gaining deeper insights into the complex mechanisms of action of herbal multicomponent preparation...

    Authors: Angela Klein, Oliver A Wrulich, Marcel Jenny, Peter Gruber, Kathrin Becker, Dietmar Fuchs, Johanna M Gostner and Florian Ãœberall
    Citation: BMC Genomics 2013 14:133
    Content type: Research article Published on:

  8. The medicinal legume Mucuna pruriens (L.) DC. has attracted attention worldwide as a source of the anti-Parkinson’s drug L-Dopa. It is also a popular green manure cover crop that offers many agronomic benefits in...

    Authors: N. Sathyanarayana, Ranjith Kumar Pittala, Pankaj Kumar Tripathi, Ratan Chopra, Heikham Russiachand Singh, Vikas Belamkar, Pardeep Kumar Bhardwaj, Jeff J. Doyle and Ashley N. Egan
    Citation: BMC Genomics 2017 18:409
    Content type: Research article Published on:

  9. Dystonia1 (DYT1) dystonia is caused by a glutamic acid deletion (ΔE) mutation in the gene encoding Torsin A in humans (HTorA). To investigate the unknown molecular and cellular mechanisms underlying DYT1 dysto...

    Authors: A-Young Kim, Jong Bok Seo, Won-tae Kim, Hee Jeong Choi, Soo-Young Kim, Genevieve Morrow, Robert M Tanguay, Hermann Steller and Young Ho Koh
    Citation: BMC Genomics 2015 16:338
    Content type: Research article Published on:

  10. The Russian wheat aphid, Diuraphis noxia Kurdjumov, is one of the most important pests of small grains throughout the temperate regions of the world. This phytotoxic aphid causes severe systemic damage symptoms i...

    Authors: Scott J Nicholson, Michael L Nickerson, Michael Dean, Yan Song, Peter R Hoyt, Hwanseok Rhee, Changhoon Kim and Gary J Puterka
    Citation: BMC Genomics 2015 16:429
    Content type: Research article Published on:

  11. Dysregulation of microRNA (miRNA) expression has been implicated in molecular genetic events leading to the progression and development of atherosclerosis. We hypothesized that miRNA expression profiles differ...

    Authors: Genesio M Karere, Jeremy P Glenn, John L VandeBerg and Laura A Cox
    Citation: BMC Genomics 2012 13:320
    Content type: Research article Published on:

  12. DNA methylation has a potential role in controlling gene expression and may, therefore, contribute to salinity adaptation in plants. Caliph medic (Medicago truncatula) is a model legume of moderate salinity toler...

    Authors: Mahmoud W. Yaish, Abbas Al-Lawati, Ibtisam Al-Harrasi and Himanshu Vishwas Patankar
    Citation: BMC Genomics 2018 19:78
    Content type: Research article Published on:

  13. Salmonella is a major bacterial pathogen associated with a large number of outbreaks of foodborne diseases. Many highly virulent serovars that cause human illness belong to Salmonella serogroup C1, and Salmonella

    Authors: Xiujuan Zhou, Bin Liu, Yanhong Liu, Chunlei Shi, Pina M. Fratamico, Lida Zhang, Dapeng Wang, Jianhua Zhang, Yan Cui, Ping Xu and Xianming Shi
    Citation: BMC Genomics 2021 22:507
    Content type: Research Published on:

  14. Carnation (Dianthus caryophyllus L.), in the family Caryophyllaceae, can be found in a wide range of colors and is a model system for studies of flower senescence. In addition, it is one of the most important flo...

    Authors: Koji Tanase, Chikako Nishitani, Hideki Hirakawa, Sachiko Isobe, Satoshi Tabata, Akemi Ohmiya and Takashi Onozaki
    Citation: BMC Genomics 2012 13:292
    Content type: Research article Published on:

  15. Sensitivity and accuracy are key points when using microarrays to detect alterations in gene expression under different conditions. Critical to the acquisition of reliable results is the preparation of the RNA...

    Authors: Matthijs Raaben, Penn Whitley, Diane Bouwmeester, Robert A Setterquist, Peter JM Rottier and Cornelis AM de Haan
    Citation: BMC Genomics 2008 9:221
    Content type: Methodology article Published on:

  16. Postnatal development of the mammalian mucosal immune system is crucial for responding to the rapid colonization by commensal bacteria and possible exposure to pathogens. This study analyzed expression pattern...

    Authors: Guanxiang Liang, Nilusha Malmuthuge, Hua Bao, Paul Stothard, Philip J. Griebel and Le Luo Guan
    Citation: BMC Genomics 2016 17:602
    Content type: Research article Published on:

  17. The Manila clam, Ruditapes philippinarum, is one of the major aquaculture species in the world and a potential sentinel organism for monitoring the status of marine ecosystems. However, genomic resources for R. p...

    Authors: Massimo Milan, Alessandro Coppe, Richard Reinhardt, Leonor M Cancela, Ricardo B Leite, Carlos Saavedra, Claudio Ciofi, Guido Chelazzi, Tomaso Patarnello, Stefania Bortoluzzi and Luca Bargelloni
    Citation: BMC Genomics 2011 12:234
    Content type: Research article Published on:

  18. Alu repeats, which account for ~10% of the human genome, were originally considered to be junk DNA. Recent studies, however, suggest that they may contain transcription factor binding sites and hence possibly ...

    Authors: Eugene Bolotin, Karthikeyani Chellappa, Wendy Hwang-Verslues, Jake M Schnabl, Chuhu Yang and Frances M Sladek
    Citation: BMC Genomics 2011 12:560
    Content type: Research article Published on:

  19. Genome-wide analysis of sequence divergence among species offers profound insights into the evolutionary processes that shape lineages. When full-genome sequencing is not feasible for a broad comparative study...

    Authors: Suzy CP Renn, Heather E Machado, Albyn Jones, Kosha Soneji, Rob J Kulathinal and Hans A Hofmann
    Citation: BMC Genomics 2010 11:271
    Content type: Methodology article Published on:

  20. It was recently reported that dairy cows fed a polyphenol-rich grape seed and grape marc meal extract (GSGME) during the transition period had an increased milk yield, but the underlying reasons remained uncle...

    Authors: Denise K. Gessner, Anne Winkler, Christian Koch, Georg Dusel, Gerhard Liebisch, Robert Ringseis and Klaus Eder
    Citation: BMC Genomics 2017 18:253
    Content type: Research article Published on:

  22. Ticks are obligate blood feeders. The midgut is the first major region of the body where blood and microbes ingested with the blood meal come in contact with the tick's internal tissues. Little is known about ...

    Authors: Jennifer M Anderson, Daniel E Sonenshine and Jesus G Valenzuela
    Citation: BMC Genomics 2008 9:552
    Content type: Research article Published on:

  23. Postoperative cognitive dysfunction (POCD) affects a large number of post-surgery patients, especially for the elderly. However, the etiology of this neurocognitive disorder is largely unknown. Even if several...

    Authors: Qiang Liu, Aisheng Hou, Yongyi Zhang, Ying Guo, Jingjing Li, Yinghao Yao, Kaimeng Niu, Hao Li, Yunlong Ma and Jiangbei Cao
    Citation: BMC Genomics 2019 20:670
    Content type: Research article Published on:

  24. Post-transcriptional control of gene expression is mostly conducted by specific elements in untranslated regions (UTRs) of mRNAs, in collaboration with specific binding proteins and RNAs. In several well chara...

    Authors: Stefan E Seemann, Susan M Sunkin, Michael J Hawrylycz, Walter L Ruzzo and Jan Gorodkin
    Citation: BMC Genomics 2012 13:214
    Content type: Research article Published on:

  26. Spontaneous tumors in dog have been demonstrated to share many features with their human counterparts, including relevant molecular targets, histological appearance, genetics, biological behavior and response ...

    Authors: Paolo Uva, Luigi Aurisicchio, James Watters, Andrey Loboda, Amit Kulkarni, John Castle, Fabio Palombo, Valentina Viti, Giuseppe Mesiti, Valentina Zappulli, Laura Marconato, Francesca Abramo, Gennaro Ciliberto, Armin Lahm, Nicola La Monica and Emanuele de Rinaldis
    Citation: BMC Genomics 2009 10:135
    Content type: Research article Published on:

  27. Cytochrome P450-dependent monooxygenases (P450s), constituting one of the largest and oldest gene superfamilies found in many organisms from bacteria to humans, play a vital role in the detoxification and inac...

    Authors: Binu Antony, Jibin Johny, Mahmoud M. Abdelazim, Jernej Jakše, Mohammed Ali Al-Saleh and Arnab Pain
    Citation: BMC Genomics 2019 20:440
    Content type: Research article Published on:

  28. Potato virus Y (PVY) is one of the most important plant viruses affecting potato production. The interactions between potato and PVY are complex and the outcome of the interactions depends on the potato genoty...

    Authors: Aymeric Goyer, Launa Hamlin, James M. Crosslin, Alex Buchanan and Jeff H. Chang
    Citation: BMC Genomics 2015 16:472
    Content type: Research article Published on:

  29. Maternal separation models in rodents are widely used to establish molecular mechanisms underlying prolonged effects of early life adversity on neurobiological and behavioral outcomes in adulthood. However, gl...

    Authors: Nikita I. Ershov, Natalya P. Bondar, Arina A. Lepeshko, Vasiliy V. Reshetnikov, Julia A. Ryabushkina and Tatiana I. Merkulova
    Citation: BMC Genomics 2018 19(Suppl 3):93
    Content type: Research Published on:

    This article is part of a Supplement: Volume 19 Supplement 3

  30. Leakage of water and ions and soluble proteins from muscle cells occurs during prolonged exercise due to ischemia causing muscle damage. Also post mortem anoxia during conversion of muscle to meat is marked by lo...

    Authors: Siriluck Ponsuksili, Elisabeth Jonas, Eduard Murani, Chirawath Phatsara, Tiranun Srikanchai, Christina Walz, Manfred Schwerin, Karl Schellander and Klaus Wimmers
    Citation: BMC Genomics 2008 9:367
    Content type: Research article Published on:

  31. Clostridium bolteae and Clostridium clostridioforme, previously included in the complex C. clostridioforme in the group Clostridium XIVa, remain difficult to distinguish by phenotypic ...

    Authors: Pierre Dehoux, Jean Christophe Marvaud, Amr Abouelleil, Ashlee M. Earl, Thierry Lambert and Catherine Dauga
    Citation: BMC Genomics 2016 17:819
    Content type: Research article Published on:

  33. Staphylococcus aureus, a leading cause of chronic or acute infections, is traditionally considered an extracellular pathogen despite repeated reports of S. aureus internalization by a variety of non-myeloid cells...

    Authors: Christian Garzoni, Patrice Francois, Antoine Huyghe, Sabine Couzinet, Caroline Tapparel, Yvan Charbonnier, Adriana Renzoni, Sacha Lucchini, Daniel P Lew, Pierre Vaudaux, William L Kelley and Jacques Schrenzel
    Citation: BMC Genomics 2007 8:171
    Content type: Research article Published on:

  34. In this study, we formulate a computational reaction model following a chemical kinetic theory approach to predict the binding rate constant for the siRNA-RISC complex formation reaction. The model allowed us ...

    Authors: Preetam Ghosh, Robert Dullea, James E Fischer, Tom G Turi, Ronald W Sarver, Chaoyang Zhang, Kalyan Basu, Sajal K Das and Bradley W Poland
    Citation: BMC Genomics 2009 10(Suppl 1):S17
    Content type: Research Published on:

    This article is part of a Supplement: Volume 10 Supplement 1

  35. Sequence closure often represents the end-point of a genome project, without a system in place for subsequent improvement and refinement. Building on the genome project of Vibrio fischeri ES114, we used a compara...

    Authors: Mark J Mandel, Eric V Stabb and Edward G Ruby
    Citation: BMC Genomics 2008 9:138
    Content type: Research article Published on:

  36. Clinical proteomics application aims at solving a specific clinical problem within the context of a clinical study. It has been growing rapidly in the field of biomarker discovery, especially in the area of ca...

    Authors: Fan Zhang and Jake Y. Chen
    Citation: BMC Genomics 2016 17(Suppl 7):522
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 7

  37. Sympathetic nerves play essential roles in the regulation of lung inflammation, and we investigated the effect of sympathetic denervation (SD) on sepsis-induced acute lung injury (ALI) in mice. Mice were rando...

    Authors: Jia Zhang, Zhao Zhang, Xinran Nie, Yingli Liu, Yong Qi and Jing Wang
    Citation: BMC Genomics 2022 23:836
    Content type: Research Published on:

  38. Kuruma shrimp, a major commercial shrimp species in the world, has two cryptic or sibling species, Marsupenaeus japonicus and Marsupenaeus pulchricaudatus. Codon usage analysis would contribute to our understandi...

    Authors: Panpan Wang, Yong Mao, Yongquan Su and Jun Wang
    Citation: BMC Genomics 2021 22:781
    Content type: Research article Published on:

  40. Floral transition is a critical event in the life cycle of a flowering plant as it determines its reproductive success. Despite extensive studies of specific genes that regulate this process, the global change...

    Authors: Anna V. Klepikova, Maria D. Logacheva, Sergey E. Dmitriev and Aleksey A. Penin
    Citation: BMC Genomics 2015 16:466
    Content type: Research article Published on:

  41. NOD2 is an innate immune receptor for the bacterial cell wall component muramyl-dipeptide. Mutations in the leucine-rich repeat region of NOD2, which lead to an impaired recognition of muramyl-dipeptide, have ...

    Authors: Philip Rosenstiel, Klaus Huse, Andre Franke, Jochen Hampe, Kathrin Reichwald, Cornelia Platzer, Roland G Roberts, Christopher G Mathew, Matthias Platzer and Stefan Schreiber
    Citation: BMC Genomics 2007 8:472
    Content type: Research article Published on:

  42. 2,3,7,8–tetrachlorodibenzo-p-dixion (TCDD) is the most potent of the dioxin congeners, capable of causing a wide range of toxic effects across numerous animal models. Previous studies have demonstrated that males...

    Authors: Jamie Lee, Stephenie D. Prokopec, John D. Watson, Ren X. Sun, Raimo Pohjanvirta and Paul C. Boutros
    Citation: BMC Genomics 2015 16:625
    Content type: Research article Published on:

  45. Korean Hanwoo cattle are known for their high meat quality, especially their high intramuscular fat compared to most other cattle breeds. Different muscles have very different meat quality traits and a study o...

    Authors: Sara de las Heras-Saldana, Ki Yong Chung, Seung Hwan Lee and Cedric Gondro
    Citation: BMC Genomics 2019 20:156
    Content type: Research article Published on:

  46. Anthozoan cnidarians are amongst the simplest animals at the tissue level of organization, but are surprisingly complex and vertebrate-like in terms of gene repertoire. As major components of tropical reef eco...

    Authors: Lauretta C Grasso, John Maindonald, Stephen Rudd, David C Hayward, Robert Saint, David J Miller and Eldon E Ball
    Citation: BMC Genomics 2008 9:540
    Content type: Research article Published on:

  47. Embryonic and fetal exposure to maternal obesity causes several maladaptive morphological and epigenetic changes in exposed offspring. The timing of these events is unclear, but changes can be observed even af...

    Authors: Sarah R. McCoski, McCauley T. Vailes, Connor E. Owens, Rebecca R. Cockrum and Alan D. Ealy
    Citation: BMC Genomics 2018 19:737
    Content type: Research article Published on:

  48. Uterine temporal and dose-dependent histopathologic, morphometric and gene expression responses to the selective estrogen receptor modulator tamoxifen (TAM) were comprehensively examined to further elucidate i...

    Authors: Cora J Fong, Lyle D Burgoon, Kurt J Williams, Agnes L Forgacs and Timothy R Zacharewski
    Citation: BMC Genomics 2007 8:151
    Content type: Research article Published on:

  49. The autoimmune regulator (Aire) gene is critical for the appropriate establishment of central immune tolerance. As one of the main controllers of promiscuous gene expression in the thymus, Aire promotes the ex...

    Authors: Pedro Paranhos Tanaka, Ernna Hérida Oliveira, Mayara Cristina Vieira-Machado, Max Jordan Duarte, Amanda Freire Assis, Karina Fittipaldi Bombonato-Prado and Geraldo Aleixo Passos
    Citation: BMC Genomics 2022 23:404
    Content type: Research Published on:

  50. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long ncRNAs (lncRNAs) and circular RNAs (circRNAs), accomplish remarkable variety of biological functions. However, the composition of ncRNAs and their in.....

    Authors: Xi Chen, Shuo Sun, Fangjie Liu, Enhui Shen, Lu Liu, Chuyu Ye, Bingguang Xiao, Michael P. Timko, Qian-Hao Zhu, Longjiang Fan and Peijian Cao
    Citation: BMC Genomics 2019 20:856
    Content type: Research article Published on:

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