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  1. Epigenetic variation may result from selection for complex traits related to metabolic processes or appear in the course of adaptation to mediate responses to exogenous stressors. Moreover epigenetic marks, in...

    Authors: Siriluck Ponsuksili, Nares Trakooljul, Sajjanar Basavaraj, Frieder Hadlich, Eduard Murani and Klaus Wimmers
    Citation: BMC Genomics 2019 20:492
  2. Mycobacterium avium subsp. paratuberculosis (MAP), the etiologic agent of Johne’s disease is spread between cattle via the fecal-oral route, yet the functional changes in the salivary gland associated with infect...

    Authors: Sanjay Mallikarjunappa, Mounir Adnane, Paul Cormican, Niel A. Karrow and Kieran G. Meade
    Citation: BMC Genomics 2019 20:491
  3. Salmonella enterica possess several iron acquisition systems, encoded on the chromosome and plasmids. Recently, we demonstrated that incompatibility group (Inc) FIB plasmid-encoded iron acquisition systems (Sit a...

    Authors: Bijay K. Khajanchi, Joshua Xu, Christopher J. Grim, Andrea R. Ottesen, Padmini Ramachandran and Steven L. Foley
    Citation: BMC Genomics 2019 20:490
  4. Juncus effusus L. (family: Juncaceae; order: Poales) is a helophytic rush growing in temperate damp or wet terrestrial habitats and is of almost cosmopolitan distribution. The species has been studied intensively...

    Authors: Muhammad Arslan, Upendra Kumar Devisetty, Martin Porsch, Ivo Große, Jochen A. Müller and Stefan G. Michalski
    Citation: BMC Genomics 2019 20:489
  5. The growing importance of the ubiquitous fungal genus Trichoderma (Hypocreales, Ascomycota) requires understanding of its biology and evolution. Many Trichoderma species are used as biofertilizers and biofungicid...

    Authors: Christian P. Kubicek, Andrei S. Steindorff, Komal Chenthamara, Gelsomina Manganiello, Bernard Henrissat, Jian Zhang, Feng Cai, Alexey G. Kopchinskiy, Eva M. Kubicek, Alan Kuo, Riccardo Baroncelli, Sabrina Sarrocco, Eliane Ferreira Noronha, Giovanni Vannacci, Qirong Shen, Igor V. Grigoriev…
    Citation: BMC Genomics 2019 20:485
  6. It is hypothesized that the highly conserved inverted repeats (IR) structure of land plant plastid genomes (plastomes) is beneficial for stabilizing plastome organization, whereas the mechanism of the occurren...

    Authors: Hong-Rui Zhang, Xian-Chun Zhang and Qiao-Ping Xiang
    Citation: BMC Genomics 2019 20:484

    The Correction to this article has been published in BMC Genomics 2019 20:523

  7. In reported plants, the bZIP family is one of the largest transcription factor families. bZIP genes play roles in the light signal, seed maturation, flower development, cell elongation, seed accumulation protein,...

    Authors: Moyang Liu, Yongdi Wen, Wenjun Sun, Zhaotang Ma, Li Huang, Qi Wu, Zizhong Tang, Tongliang Bu, Chenglei Li and Hui Chen
    Citation: BMC Genomics 2019 20:483
  8. Global biodiversity is decreasing at an alarming rate and amphibians are at the forefront of this crisis. Understanding the factors that negatively impact amphibian populations and effectively monitoring their...

    Authors: Timothy A. Clay, Michael A. Steffen, Michael L. Treglia, Carolyn D. Torres, Ana Lilia Trujano-Alvarez and Ronald M. Bonett
    Citation: BMC Genomics 2019 20:482
  9. Due to the recent domestication of peanut from a single tetraploidization event, relatively little genetic diversity underlies the extensive morphological and agronomic diversity in peanut cultivars today. To ...

    Authors: Paul I. Otyama, Andrew Wilkey, Roshan Kulkarni, Teshale Assefa, Ye Chu, Josh Clevenger, Dan J. O’Connor, Graeme C. Wright, Stanley W. Dezern, Gregory E. MacDonald, Noelle L. Anglin, Ethalinda K. S. Cannon, Peggy Ozias-Akins and Steven B. Cannon
    Citation: BMC Genomics 2019 20:481
  10. Plasmids play an vital role in driving the rapid global spread of antimicrobial resistance and adaptation to changing ambient conditions. It has been suggested that the presence of plasmids can pose tremendous...

    Authors: Dan Long, Lan-lan Zhu, Fang-ling Du, Tian-xin Xiang, La-Gen Wan, Dan-dan Wei, Wei Zhang and Yang Liu
    Citation: BMC Genomics 2019 20:480
  11. The mammalian major histocompatibility complex (MHC) harbours clusters of genes associated with the immunological defence of animals against infectious pathogens. At present, no complete MHC physical map is av...

    Authors: Chaokun Li, Longxin Chen, Xuefeng Liu, Xiaoqian Shi, Yu Guo, Rui Huang, Fangyuan Nie, Changming Zheng, Chenglin Zhang and Runlin Z. Ma
    Citation: BMC Genomics 2019 20:479
  12. Salt pond restoration aims to recover the environmental damages that accumulated over the long history of salt production. Of the restoration strategies, phytoremediation that utilizes salt-tolerant plants and...

    Authors: Huyen-Trang Tran, Hao-Chu Wang, Tsai-Wen Hsu, Rakesh Sarkar, Chao-Li Huang and Tzen-Yuh Chiang
    Citation: BMC Genomics 2019 20:478
  13. Global RNA sequencing technologies have revealed widespread RNA polymerase II (Pol II) transcription outside of gene promoters. Small 5′-capped RNA sequencing (Start-seq) originally developed for the detection...

    Authors: Adam Scheidegger, Carissa J. Dunn, Ann Samarakkody, Nii Koney-Kwaku Koney, Danielle Perley, Ramendra N. Saha and Sergei Nechaev
    Citation: BMC Genomics 2019 20:477
  14. The redundancy of genomic resources, including transcript and molecular markers, and their uncertain position in the genome have dramatically hindered the study of traits in ramie, an important natural fiber c...

    Authors: Yanzhou Wang, Zheng Zeng, Fu Li, Xiufeng Yang, Xinyue Gao, Yonghong Ma, Jing Rao, Hengyun Wang and Touming Liu
    Citation: BMC Genomics 2019 20:476
  15. When puberty starts before males reach harvest size, animal welfare and sustainability issues occur in Atlantic salmon (Salmo salar) aquaculture. Hallmarks of male puberty are an increased proliferation activity ...

    Authors: Diego Crespo, Jan Bogerd, Elisabeth Sambroni, Florence LeGac, Eva Andersson, Rolf B. Edvardsen, Elisabeth Jönsson Bergman, Björn Thrandur Björnsson, Geir Lasse Taranger and Rüdiger W. Schulz
    Citation: BMC Genomics 2019 20:475
  16. Extracellular vesicles (EVs) are small membrane vesicles secreted by the cells that mediate intercellular transfer of molecules and contribute to transduction of various signals. Viral infection and action of ...

    Authors: Andrii Slonchak, Brian Clarke, Jason Mackenzie, Alberto Anastacio Amarilla, Yin Xiang Setoh and Alexander A. Khromykh
    Citation: BMC Genomics 2019 20:474
  17. Reliable indicators for the onset of flowering are not available for most perennial monocarpic species, representing a drawback for crops such as bamboo, agave and banana. The ability to predict and control th...

    Authors: Emmanuel Avila de Dios, Luis Delaye and June Simpson
    Citation: BMC Genomics 2019 20:473
  18. Puddled transplanted system of rice cultivation despite having several benefits, is a highly labor, water and energy intensive system. In the face of changing climatic conditions, a successful transition from ...

    Authors: Sushil Raj Subedi, Nitika Sandhu, Vikas Kumar Singh, Pallavi Sinha, Santosh Kumar, S. P. Singh, Surya Kant Ghimire, Madhav Pandey, Ram Baran Yadaw, Rajeev K. Varshney and Arvind Kumar
    Citation: BMC Genomics 2019 20:471
  19. A critical goal in biology is to relate the phenotype to the genotype, that is, to find the genetic determinants of various traits. However, while simple monofactorial determinants are relatively easy to ident...

    Authors: George S. Long, Mohammed Hussen, Jonathan Dench and Stéphane Aris-Brosou
    Citation: BMC Genomics 2019 20:470
  20. The pearl oyster Pinctada fucata martensii (Pfu.), widely cultured in the South China Sea, is a precious source of sea pearls and calcifying materials. A yellow shell variety of Pfu. was obtained after years of a...

    Authors: Meng Xu, Jing Huang, Yu Shi, Hua Zhang and Maoxian He
    Citation: BMC Genomics 2019 20:469
  21. The causes and consequences of genome size variation across Eukaryotes, which spans five orders of magnitude, have been hotly debated since before the advent of genome sequencing. Previous studies have mostly ...

    Authors: J. Blommaert, S. Riss, B. Hecox-Lea, D. B. Mark Welch and C. P. Stelzer
    Citation: BMC Genomics 2019 20:466
  22. The Neotropical fruit fly Drosophila paulistorum (Diptera: Drosophilidae) is a species complex in statu nascendi comprising six reproductively isolated semispecies, each harboring mutualistic Wolbachia strains. A...

    Authors: Guilherme C. Baião, Daniela I. Schneider, Wolfgang J. Miller and Lisa Klasson
    Citation: BMC Genomics 2019 20:465
  23. The WRKY gene family is one of the most important families in higher plants. As transcription factors, they actively respond to biotic and abiotic stress and are also involved in plant development. Chinese juj...

    Authors: Chaoling Xue, Hongtai Li, Zhiguo Liu, Lili Wang, Yitong Zhao, Ximeng Wei, Hu Fang, Mengjun Liu and Jin Zhao
    Citation: BMC Genomics 2019 20:464
  24. The diamondback moth (DBM), Plutella xylostella (L.), is a major pest of cruciferous crops worldwide. While the species has become a model for genomics, post-transcriptional mechanisms associated with development...

    Authors: Qian Zhao, Weimin Zhong, Weiyi He, Yiying Li, Yaqing Li, Tianpu Li, Liette Vasseur and Minsheng You
    Citation: BMC Genomics 2019 20:463
  25. Isopods constitute a particular group of crustaceans that has successfully colonized all environments including marine, freshwater and terrestrial habitats. Their ability to use various food sources, especiall...

    Authors: Marius Bredon, Benjamin Herran, Baptiste Lheraud, Joanne Bertaux, Pierre Grève, Bouziane Moumen and Didier Bouchon
    Citation: BMC Genomics 2019 20:462
  26. The improvement of feed efficiency is a key economic goal within the pig production industry. The objective of this study was to examine transcriptomic differences in both the liver and muscle of pigs divergen...

    Authors: Stafford Vigors, John V. O’Doherty, Kenneth Bryan and Torres Sweeney
    Citation: BMC Genomics 2019 20:461
  27. Hibernation is a physiological state exploited by many animals exposed to prolonged adverse environmental conditions associated with winter. Large changes in metabolism and cellular function occur, with many s...

    Authors: Alexander Capraro, Denis O’Meally, Shafagh A. Waters, Hardip R. Patel, Arthur Georges and Paul D. Waters
    Citation: BMC Genomics 2019 20:460
  28. The most widely used human genome reference assembly hg19 harbors minor alleles at 2.18 million positions as revealed by 1000 Genome Phase 3 dataset. Although this is less than 2% of the 89 million variants re...

    Authors: Harsh G. Shukla, Pushpinder Singh Bawa and Subhashini Srinivasan
    Citation: BMC Genomics 2019 20:459
  29. Chinese bayberry (Myrica rubra Sieb. & Zucc.) is an economically important fruit tree characterized by its juicy fruits rich in antioxidant compounds. Elucidating the genetic basis of the biosynthesis of active a...

    Authors: Haiying Ren, Haiyan Yu, Shuwen Zhang, Senmiao Liang, Xiliang Zheng, Shujian Zhang, Pu Yao, Hongkun Zheng and Xingjiang Qi
    Citation: BMC Genomics 2019 20:458
  30. Ricinus communis is a highly economically valuable oil crop plant from the spurge family, Euphorbiaceae. However, the available reference genomes are incomplete and to date studies on ricinoleic acid biosynthesis...

    Authors: Lijun Wang, Xiaoling Jiang, Lei Wang, Wei Wang, Chunling Fu, Xingchu Yan and Xinxin Geng
    Citation: BMC Genomics 2019 20:456
  31. Closing gaps in draft genomes is an important post processing step in genome assembly. It leads to more complete genomes, which benefits downstream genome analysis such as annotation and genotyping. Several to...

    Authors: Chong Chu, Xin Li and Yufeng Wu
    Citation: BMC Genomics 2019 20(Suppl 5):426

    This article is part of a Supplement: Volume 20 Supplement 5

  32. A popular strategy to study alternative splicing in non-model organisms starts from sequencing the entire transcriptome, then assembling the reads by using de novo transcriptome assembly algorithms to obtain p...

    Authors: Shuhua Fu, Peter L. Chang, Maren L. Friesen, Natasha L. Teakle, Aaron M. Tarone and Sing-Hoi Sze
    Citation: BMC Genomics 2019 20(Suppl 5):425

    This article is part of a Supplement: Volume 20 Supplement 5

  33. Motifs are crucial patterns that have numerous applications including the identification of transcription factors and their binding sites, composite regulatory patterns, similarity between families of proteins...

    Authors: Peng Xiao, Martin Schiller and Sanguthevar Rajasekaran
    Citation: BMC Genomics 2019 20(Suppl 5):424

    This article is part of a Supplement: Volume 20 Supplement 5

  34. High throughput sequencing has spurred the development of metagenomics, which involves the direct analysis of microbial communities in various environments such as soil, ocean water, and the human body. Many e...

    Authors: Nathan LaPierre, Serghei Mangul, Mohammed Alser, Igor Mandric, Nicholas C. Wu, David Koslicki and Eleazar Eskin
    Citation: BMC Genomics 2019 20(Suppl 5):423

    This article is part of a Supplement: Volume 20 Supplement 5

  35. Ribo-seq is a popular technique for studying translation and its regulation. A Ribo-seq experiment produces a snap-shot of the location and abundance of actively translating ribosomes within a cell’s transcrip...

    Authors: Patrick Perkins, Serina Mazzoni-Putman, Anna Stepanova, Jose Alonso and Steffen Heber
    Citation: BMC Genomics 2019 20(Suppl 5):422

    This article is part of a Supplement: Volume 20 Supplement 5

  36. Coxiella burnetii is a zoonotic pathogen that resides in wild and domesticated animals across the globe and causes a febrile illness, Q fever, in humans. An improved understanding of the genetic diversity of C. b...

    Authors: Claudia M. Hemsley, Paul A. O’Neill, Angela Essex-Lopresti, Isobel H. Norville, Tim P. Atkins and Richard W. Titball
    Citation: BMC Genomics 2019 20:441
  37. Natural rubber, an indispensable commodity used in approximately 40,000 products, is fundamental to the tire industry. The rubber tree species Hevea brasiliensis (Willd. ex Adr. de Juss.) Muell-Arg., which is nat...

    Authors: Camila Campos Mantello, Lucas Boatwright, Carla Cristina da Silva, Erivaldo Jose Scaloppi Jr, Paulo de Souza Goncalves, W. Brad Barbazuk and Anete Pereira de Souza
    Citation: BMC Genomics 2019 20:455
  38. Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of cellular processes in diseases such as cancer, although the functions of most remain poorly understood. To address this, here we apply a nov...

    Authors: Kevin Walters, Radmir Sarsenov, Wen Siong Too, Roseanna K. Hare, Ian C. Paterson, Daniel W. Lambert, Stephen Brown and James R. Bradford
    Citation: BMC Genomics 2019 20:454
  39. Recent advances in genomics have greatly increased research opportunities for non-model species. For wildlife, a growing availability of reference genomes means that population genetics is no longer restricted...

    Authors: Belinda Wright, Katherine A. Farquharson, Elspeth A. McLennan, Katherine Belov, Carolyn J. Hogg and Catherine E. Grueber
    Citation: BMC Genomics 2019 20:453
  40. Full RNA-Seq is a fundamental research tool for whole transcriptome analysis. However, it is too costly and time consuming to be used in routine clinical practice. We evaluated the transcript quantification ag...

    Authors: A. C. Picornell, I. Echavarria, E. Alvarez, S. López-Tarruella, Y. Jerez, K. Hoadley, J. S. Parker, M. del Monte-Millán, R. Ramos-Medina, J. Gayarre, I. Ocaña, M. Cebollero, T. Massarrah, F. Moreno, J. A. García Saenz, H. Gómez Moreno…
    Citation: BMC Genomics 2019 20:452
  41. Herpetospermum pedunculosum (Ser.) Baill is annual scandent herbs. They are used in the treatment of piles, inflammation of the stomach and the intestines. It can survive the extreme environment of the Tibetan Pl...

    Authors: Yong Zhao, Fuling Xu, Jia Liu, Fachun Guan, Hong Quan and Fanjuan Meng
    Citation: BMC Genomics 2019 20:451
  42. Directed DNA methylation on N6-adenine (6mA), N4-cytosine (4mC), and C5-cytosine (5mC) can potentially increase DNA coding capacity and regulate a variety of biological functions. These modifications are relat...

    Authors: Zach K. O’Brown, Konstantinos Boulias, Jie Wang, Simon Yuan Wang, Natasha M. O’Brown, Ziyang Hao, Hiroki Shibuya, Paul-Enguerrand Fady, Yang Shi, Chuan He, Sean G. Megason, Tao Liu and Eric L. Greer
    Citation: BMC Genomics 2019 20:445
  43. Host genetic backgrounds affect gene functions. The genetic backgrounds of genetically engineered organisms must be identified to confirm their genetic backgrounds identity with those of recipients. Marker-ass...

    Authors: Tiantian Li, Zhiwei Fang, Hai Peng, Junfei Zhou, Pengcheng Liu, Yanyan Wang, Wenhui Zhu, Lun Li, Quanfang Zhang, Lihong Chen, Lili Li, Zhihao Liu, Weixiong Zhang, Wenxue Zhai, Long Lu and Lifen Gao
    Citation: BMC Genomics 2019 20:444
  44. Trait ontology (TO) analysis is a powerful system for functional annotation and enrichment analysis of genes. However, given the complexity of the molecular mechanisms underlying phenomes, only a few hundred g...

    Authors: Qingchun Pan, Junfeng Wei, Feng Guo, Suiyong Huang, Yong Gong, Hao Liu, Jianxiao Liu and Lin Li
    Citation: BMC Genomics 2019 20:443
  45. Alternative splicing (AS) is a regulatory mechanism used to create many forms of mature messengers RNAs (mRNAs) from the same gene. Sequencing of RNA (RNA-Seq) is an advanced technology, which has been utilized b...

    Authors: Vishwas Sharma, Amrita Nandan, Harpreet Singh, Suyash Agarwal, Richa Tripathi, Dhirendra Narain Sinha and Ravi Mehrotra
    Citation: BMC Genomics 2019 20:442

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