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  1. BAHD acyltransferases are involved in the synthesis and elaboration of a wide variety of secondary metabolites. Previous research has shown that characterized proteins from this family fall broadly into five m...

    Authors: Lindsey K Tuominen, Virgil E Johnson and Chung-Jui Tsai
    Citation: BMC Genomics 2011 12:236
    Content type: Research article Published on:

  2. Resistance of soybean (Glycine max L. Merr.) cultivars to populations of cyst nematode (SCN; Heterodera glycines I.) was complicated by the diversity of HG Types (biotypes), the multigenic nature of resistance an...

    Authors: Wei Chang, Limin Dong, Zizhen Wang, Haibo Hu, Yingpeng Han, Weili Teng, Hongxia Zhang, Maozu Guo and Wenbin Li
    Citation: BMC Genomics 2011 12:233
    Content type: Research article Published on:

  3. Changes in DNA methylation in the mammalian genome during development are frequent events and play major roles regulating gene expression and other developmental processes. It is necessary to identify these ev...

    Authors: Ping Liang, Fei Song, Srimoyee Ghosh, Evan Morien, Maochun Qin, Saleh Mahmood, Kyoko Fujiwara, Jun Igarashi, Hiroki Nagase and William A Held
    Citation: BMC Genomics 2011 12:231
    Content type: Research article Published on:

  4. Genomic aberrations can be used to determine cancer diagnosis and prognosis. Clinically relevant novel aberrations can be discovered using high-throughput assays such as Single Nucleotide Polymorphism (SNP) ar...

    Authors: Fabio Parisi, Stephan Ariyan, Deepak Narayan, Antonella Bacchiocchi, Kathleen Hoyt, Elaine Cheng, Fang Xu, Peining Li, Ruth Halaban and Yuval Kluger
    Citation: BMC Genomics 2011 12:230
    Content type: Research article Published on:

  5. Down syndrome (DS; trisomy 21) is the most common genetic cause of mental retardation in the human population and key molecular networks dysregulated in DS are still unknown. Many different experimental techni...

    Authors: Mireia Vilardell, Axel Rasche, Anja Thormann, Elisabeth Maschke-Dutz, Luis A Pérez-Jurado, Hans Lehrach and Ralf Herwig
    Citation: BMC Genomics 2011 12:229
    Content type: Research article Published on:

  6. The transcriptional regulatory network is considered to be built from a set of circuit patterns called network motifs. Experimental studies have provided instances where a feedforward circuit (FFC) appears wit...

    Authors: Hisakazu Iwama, Koji Murao, Hitomi Imachi and Toshihiko Ishida
    Citation: BMC Genomics 2011 12:228
    Content type: Research article Published on:

  7. The garden pea, Pisum sativum, is among the best-investigated legume plants and of significant agro-commercial relevance. Pisum sativum has a large and complex genome and accordingly few comprehensive genomic res...

    Authors: Susanne U Franssen, Roshan P Shrestha, Andrea Bräutigam, Erich Bornberg-Bauer and Andreas PM Weber
    Citation: BMC Genomics 2011 12:227
    Content type: Research article Published on:

  8. A decline in the discovery of new antibacterial drugs, coupled with a persistent rise in the occurrence of drug-resistant bacteria, has highlighted antibiotics as a diminishing resource. The future development...

    Authors: Andy Hesketh, Chris Hill, Jehan Mokhtar, Gabriela Novotna, Ngat Tran, Mervyn Bibb and Hee-Jeon Hong
    Citation: BMC Genomics 2011 12:226
    Content type: Research article Published on:

  9. Gene expression profiling studies of mastitis in ruminants have provided key but fragmented knowledge for the understanding of the disease. A systematic combination of different expression profiling studies vi...

    Authors: Sem Genini, Bouabid Badaoui, Gert Sclep, Stephen C Bishop, Dave Waddington, Marie-Hélène Pinard van der Laan, Christophe Klopp, Cédric Cabau, Hans-Martin Seyfert, Wolfram Petzl, Kirsty Jensen, Elizabeth J Glass, Astrid de Greeff, Hilde E Smith, Mari A Smits, Ingrid Olsaker…
    Citation: BMC Genomics 2011 12:225
    Content type: Research article Published on:

  10. Diapause, a state of arrested development accompanied by a marked decrease of metabolic rate, helps insects to overcome unfavorable seasons. Helicoverpa armigera (Har) undergoes pupal diapause, but the molecular ...

    Authors: Bin Bao and Wei-Hua Xu
    Citation: BMC Genomics 2011 12:224
    Content type: Research article Published on:

  11. Parasite-vector interactions are fundamental in the transmission of vector-borne diseases such as leishmaniasis. Leishmania development in the vector sand fly is confined to the digestive tract, where sand fly mi...

    Authors: Anna Dostálová, Jan Votýpka, Amanda J Favreau, Kent D Barbian, Petr Volf, Jesus G Valenzuela and Ryan C Jochim
    Citation: BMC Genomics 2011 12:223
    Content type: Research article Published on:

  12. During murine hypothalamic development, different neuroendocrine cell phenotypes are generated in overlapping periods; this suggests that cell-type specific developmental programs operate to achieve complete m...

    Authors: Magdalena Guerra-Crespo, Carlos Pérez-Monter, Sarath Chandra Janga, Santiago Castillo-Ramírez, Rosa María Gutiérrez-Rios, Patricia Joseph-Bravo, Leonor Pérez-Martínez and Jean-Louis Charli
    Citation: BMC Genomics 2011 12:222
    Content type: Research article Published on:

  13. The insect order Neuroptera encompasses more than 5,700 described species. To date, only three neuropteran mitochondrial genomes have been fully and one partly sequenced. Current knowledge on neuropteran mitoc...

    Authors: Enrico Negrisolo, Massimiliano Babbucci and Tomaso Patarnello
    Citation: BMC Genomics 2011 12:221
    Content type: Research article Published on:

  14. Root-knot nematodes are sedentary endoparasites that can infect more than 3000 plant species. Root-knot nematodes cause an estimated $100 billion annual loss worldwide. For successful establishment of the root...

    Authors: Heba MM Ibrahim, Parsa Hosseini, Nadim W Alkharouf, Ebtissam HA Hussein, Abd El Kader Y Gamal El-Din, Mohammed AM Aly and Benjamin F Matthews
    Citation: BMC Genomics 2011 12:220
    Content type: Research article Published on:

  15. Our previous studies revealed that a new disease form of streptococcal toxic shock syndrome (STSS) is associated with specific Streptococcus suis serotype 2 (SS2) strains. To achieve a better understanding of the...

    Authors: Zuowei Wu, Ming Li, Changjun Wang, Jing Li, Na Lu, Ruifen Zhang, Yongqiang Jiang, Ruifu Yang, Cuihua Liu, Hui Liao, George F Gao, Jiaqi Tang and Baoli Zhu
    Citation: BMC Genomics 2011 12:219
    Content type: Research article Published on:

  16. Saccharomyces cerevisiae and Pichia pastoris are two of the most relevant microbial eukaryotic platforms for the production of recombinant proteins. Their known genome sequences enabled several transcriptomic pro...

    Authors: Kristin Baumann, Laura Dato, Alexandra B Graf, Gianni Frascotti, Martin Dragosits, Danilo Porro, Diethard Mattanovich, Pau Ferrer and Paola Branduardi
    Citation: BMC Genomics 2011 12:218
    Content type: Research article Published on:

  17. Flax (Linum usitatissimum L.) is an important source of oil rich in omega-3 fatty acids, which have proven health benefits and utility as an industrial raw material. Flax seeds also contain lignans which are asso...

    Authors: Raja Ragupathy, Rajkumar Rathinavelu and Sylvie Cloutier
    Citation: BMC Genomics 2011 12:217
    Content type: Research article Published on:

  18. In the presence of drought and other desiccating stresses, plants synthesize and redistribute the phytohormone abscisic acid (ABA). ABA promotes plant water conservation by acting on specialized cells in the l...

    Authors: Rui-Sheng Wang, Sona Pandey, Song Li, Timothy E Gookin, Zhixin Zhao, Réka Albert and Sarah M Assmann
    Citation: BMC Genomics 2011 12:216
    Content type: Research article Published on:

  19. Schistosomiasis remains an important parasitic disease and a major economic problem in many countries. The Schistosoma mansoni genome and predicted proteome sequences were recently published providing the opportu...

    Authors: Luiza F Andrade, Laila A Nahum, Lívia GA Avelar, Larissa L Silva, Adhemar Zerlotini, Jerônimo C Ruiz and Guilherme Oliveira
    Citation: BMC Genomics 2011 12:215
    Content type: Research article Published on:

  20. Due to its overarching role in genome function, sequence-dependent DNA curvature continues to attract great attention. The DNA double helix is not a rigid cylinder, but presents both curvature and flexibility ...

    Authors: Ali Masoudi-Nejad, Sara Movahedi and Ruy Jáuregui
    Citation: BMC Genomics 2011 12:214
    Content type: Research article Published on:

  21. Genome-wide screening in human and mouse cells using RNA interference and open reading frame over-expression libraries is rapidly becoming a viable experimental approach for many research labs. There are a var...

    Authors: Troy Ketela, Lawrence E Heisler, Kevin R Brown, Ron Ammar, Dahlia Kasimer, Anuradha Surendra, Elke Ericson, Kim Blakely, Dina Karamboulas, Andrew M Smith, Tanja Durbic, Anthony Arnoldo, Kahlin Cheung-Ong, Judice LY Koh, Shuba Gopal, Glenn S Cowley…
    Citation: BMC Genomics 2011 12:213
    Content type: Methodology article Published on:

  22. While an increase in bone marrow adiposity is associated with age-related bone disease, the function of bone marrow adipocytes has not been studied. The aim of this study was to characterize and compare the ag...

    Authors: Li-Fen Liu, Wen-Jun Shen, Masami Ueno, Shailja Patel and Fredric B Kraemer
    Citation: BMC Genomics 2011 12:212
    Content type: Research article Published on:

  23. Milkweeds (Asclepias L.) have been extensively investigated in diverse areas of evolutionary biology and ecology; however, there are few genetic resources available to facilitate and compliment these studies. Thi...

    Authors: Shannon CK Straub, Mark Fishbein, Tatyana Livshultz, Zachary Foster, Matthew Parks, Kevin Weitemier, Richard C Cronn and Aaron Liston
    Citation: BMC Genomics 2011 12:211
    Content type: Research article Published on:

  24. Burkholderia rhizoxinica is an intracellular symbiont of the phytopathogenic zygomycete Rhizopus microsporus, the causative agent of rice seedling blight. The endosymbiont produces the antimitotic macrolide rhizo...

    Authors: Gerald Lackner, Nadine Moebius, Laila P Partida-Martinez, Sebastian Boland and Christian Hertweck
    Citation: BMC Genomics 2011 12:210
    Content type: Research article Published on:

  25. Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in...

    Authors: Leah M Prentice, Xavier d'Anglemont de Tassigny, Steven McKinney, Teresa Ruiz de Algara, Damian Yap, Gulisa Turashvili, Steven Poon, Margaret Sutcliffe, Pat Allard, Angela Burleigh, John Fee, David G Huntsman, William H Colledge and Samuel AJ Aparicio
    Citation: BMC Genomics 2011 12:209
    Content type: Research article Published on:

  26. The existence of a genetic basis for host responses to bacterial intramammary infections has been widely documented, but the underlying mechanisms and the genes are still largely unknown. Previously, two diver...

    Authors: Cécile MD Bonnefont, Mehdi Toufeer, Cécile Caubet, Eliane Foulon, Christian Tasca, Marie-Rose Aurel, Dominique Bergonier, Séverine Boullier, Christèle Robert-Granié, Gilles Foucras and Rachel Rupp
    Citation: BMC Genomics 2011 12:208
    Content type: Research article Published on:

  27. Small bacterial RNAs (sRNAs) have been shown to participate in the regulation of gene expression and have been identified in numerous prokaryotic species. Some of them are involved in the regulation of virulen...

    Authors: David Hot, Stéphanie Slupek, Bérénice Wulbrecht, Anthony D'Hondt, Christine Hubans, Rudy Antoine, Camille Locht and Yves Lemoine
    Citation: BMC Genomics 2011 12:207
    Content type: Research article Published on:

  30. The proximal region of murine Chr 2 has long been known to harbour one or more imprinted genes from classic genetic studies involving reciprocal translocations. No imprinted gene had been identified from this ...

    Authors: Qianwei Wang, Jacqueline Chow, Jenny Hong, Anne Ferguson Smith, Carol Moreno, Peter Seaby, Paul Vrana, Kamelia Miri, Joon Tak, Eu Ddeum Chung, Gabriela Mastromonaco, Isabella Caniggia and Susannah Varmuza
    Citation: BMC Genomics 2011 12:204
    Content type: Research article Published on:

  31. Significant differences in G+C content between different isochore types suggest that the nucleosome positioning patterns in DNA of the isochores should be different as well.

    Authors: Zakharia M Frenkel, Thomas Bettecken and Edward N Trifonov
    Citation: BMC Genomics 2011 12:203
    Content type: Research article Published on:

  32. Next-generation sequencing is providing researchers with a relatively fast and affordable option for developing genomic resources for organisms that are not among the traditional genetic models. Here we presen...

    Authors: Bonnie A Fraser, Cameron J Weadick, Ilana Janowitz, F Helen Rodd and Kimberly A Hughes
    Citation: BMC Genomics 2011 12:202
    Content type: Research article Published on:

  33. Saccharomyces cerevisiae (Baker's yeast) is found in diverse ecological niches and is characterized by high adaptive potential under challenging environments. In spite of recent advances on the study of yeast gen...

    Authors: Laura Carreto, Maria F Eiriz, Inês Domingues, Dorit Schuller, Gabriela R Moura and Manuel AS Santos
    Citation: BMC Genomics 2011 12:201
    Content type: Research article Published on:

  34. The decline noticed in several fertility traits of dairy cattle over the past few decades is of major concern. Understanding of the genomic factors underlying fertility, which could have potential applications...

    Authors: Arun Kommadath, Henri Woelders, Bonne Beerda, Herman A Mulder, Agnes AC de Wit, Roel F Veerkamp, Marinus FW te Pas and Mari A Smits
    Citation: BMC Genomics 2011 12:200
    Content type: Research article Published on:

  35. Alfalfa, [Medicago sativa (L.) sativa], a widely-grown perennial forage has potential for development as a cellulosic ethanol feedstock. However, the genomics of alfalfa, a non-model species, is still in its infa...

    Authors: S Samuel Yang, Zheng Jin Tu, Foo Cheung, Wayne Wenzhong Xu, JoAnn FS Lamb, Hans-Joachim G Jung, Carroll P Vance and John W Gronwald
    Citation: BMC Genomics 2011 12:199
    Content type: Research article Published on:

  37. Infectious laryngotracheitis virus (ILTV) is an alphaherpesvirus that causes acute respiratory disease in chickens worldwide. To date, only one complete genomic sequence of ILTV has been reported. This sequenc...

    Authors: Sang-Won Lee, Philip F Markham, John F Markham, Ivonne Petermann, Amir H Noormohammadi, Glenn F Browning, Nino P Ficorilli, Carol A Hartley and Joanne M Devlin
    Citation: BMC Genomics 2011 12:197
    Content type: Research article Published on:

  38. Nerve growth factor (NGF) is a potent growth factor that plays a key role in neuronal cell differentiation and may also play a role in hematopoietic differentiation. It has been shown that NGF induced synergis...

    Authors: Priyanka Dutta, Alexandra Koch, Bjoern Breyer, Heike Schneider, Oliver Dittrich-Breiholz, Michael Kracht and Teruko Tamura
    Citation: BMC Genomics 2011 12:196
    Content type: Research article Published on:

  39. Mixtures of chemicals present in aquatic environments may elicit toxicity due to additive or synergistic effects among the constituents or, vice versa, the adverse outcome may be reduced by antagonistic intera...

    Authors: Francesco Dondero, Mohamed Banni, Alessandro Negri, Lara Boatti, Alessandro Dagnino and Aldo Viarengo
    Citation: BMC Genomics 2011 12:195
    Content type: Research article Published on:

  41. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an environmental contaminant that elicits a broad spectrum of toxic effects in a species-specific manner. Current risk assessment practices routinely extrapolate resu...

    Authors: Edward Dere, Andrea W Lee, Lyle D Burgoon and Timothy R Zacharewski
    Citation: BMC Genomics 2011 12:193
    Content type: Research article Published on:

  43. Jatropha curcas L. is an important non-edible oilseed crop with promising future in biodiesel production. However, factors like oil yield, oil composition, toxic compounds in oil cake, pests and diseases limit it...

    Authors: Purushothaman Natarajan and Madasamy Parani
    Citation: BMC Genomics 2011 12:191
    Content type: Research article Published on:

  44. Milling yield and eating quality are two important grain quality traits in rice. To identify the genes involved in these two traits, we performed a deep transcriptional analysis of developing seeds using both ...

    Authors: R C Venu, M V Sreerekha, Kan Nobuta, André Beló, Yuese Ning, Gynheung An, Blake C Meyers and Guo-Liang Wang
    Citation: BMC Genomics 2011 12:190
    Content type: Research article Published on:

  45. Technological advances are progressively increasing the application of genomics to a wider array of economically and ecologically important species. High-density maps enriched for transcribed genes facilitate ...

    Authors: Leandro G Neves, Eva MC Mamani, Acelino C Alfenas, Matias Kirst and Dario Grattapaglia
    Citation: BMC Genomics 2011 12:189
    Content type: Research article Published on:

  46. Common carp is one of the most important aquaculture teleost fish in the world. Common carp and other closely related Cyprinidae species provide over 30% aquaculture production in the world. However, common ca...

    Authors: Peng Xu, Jiongtang Li, Yan Li, Runzi Cui, Jintu Wang, Jian Wang, Yan Zhang, Zixia Zhao and Xiaowen Sun
    Citation: BMC Genomics 2011 12:188
    Content type: Research article Published on:

  47. Staphylococcus aureus is associated with a spectrum of symbiotic relationships with its human host from carriage to sepsis and is frequently associated with nosocomial and community-acquired infections, thus the ...

    Authors: Robert Boissy, Azad Ahmed, Benjamin Janto, Josh Earl, Barry G Hall, Justin S Hogg, Gordon D Pusch, Luisa N Hiller, Evan Powell, Jay Hayes, Susan Yu, Sandeep Kathju, Paul Stoodley, J Christopher Post, Garth D Ehrlich and Fen Z Hu
    Citation: BMC Genomics 2011 12:187
    Content type: Research article Published on:

  48. Functional studies have demonstrated that microRNAs (miRNAs or miRs) play critical roles in a wide spectrum of biological processes including development and disease pathogenesis. To investigate the functional...

    Authors: Tingting Li, Rimao Wu, Yong Zhang and Dahai Zhu
    Citation: BMC Genomics 2011 12:186
    Content type: Research article Published on:

  50. MicroRNAs (miRNAs) are important genetic elements that regulate the expression of thousands of human genes. Polymorphisms affecting miRNA biogenesis, dosage and target recognition may represent potentially fun...

    Authors: Malgorzata Marcinkowska, Maciej Szymanski, Wlodzimierz J Krzyzosiak and Piotr Kozlowski
    Citation: BMC Genomics 2011 12:183
    Content type: Research article Published on:

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BMC Genomics

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