Regard JB, Sato IT, Coughlin SR: Anatomical profiling of G protein-coupled receptor expression. Cell. 2008, 135 (3): 561-571. 10.1016/j.cell.2008.08.040.
Article
PubMed Central
CAS
PubMed
Google Scholar
Song H, Luo J, Luo W, Weng J, Wang Z, Li B, Li D, Liu M: Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway. J Biol Chem. 2008, 283 (52): 36687-36697. 10.1074/jbc.M800721200.
Article
PubMed Central
CAS
PubMed
Google Scholar
Neer EJ: Heterotrimeric G proteins: organizers of transmembrane signals. Cell. 1995, 80 (2): 249-257. 10.1016/0092-8674(95)90407-7.
Article
CAS
PubMed
Google Scholar
Kuroyanagi Y, Kaneko Y, Muta K, Park BS, Moi P, Ausenda S, Cappellini MD, Ikuta T: cAMP differentially regulates gamma-globin gene expression in erythroleukemic cells and primary erythroblasts through c-Myb expression. Biochem Biophys Res Commun. 2006, 344 (3): 1038-1047. 10.1016/j.bbrc.2006.03.203.
Article
CAS
PubMed
Google Scholar
Cokic VP, Beleslin-Cokic BB, Tomic M, Stojilkovic SS, Noguchi CT, Schechter AN: Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells. Blood. 2006, 108 (1): 184-191. 10.1182/blood-2005-11-4454.
Article
CAS
PubMed
Google Scholar
Cokic VP, Andric SA, Stojilkovic SS, Noguchi CT, Schechter AN: Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells. Blood. 2008, 111 (3): 1117-1123.
Article
PubMed Central
CAS
PubMed
Google Scholar
Cokic VP, Smith RD, Beleslin-Cokic BB, Njoroge JM, Miller JL, Gladwin MT, Schechter AN: Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase. J Clin Invest. 2003, 111 (2): 231-239.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hescheler J, Rosenthal W, Trautwein W, Schultz G: The GTP binding protein, Go, regulates neuronal Ca2+ channels. Nature. 1987, 325 (6103): 445-447. 10.1038/325445a0.
Article
CAS
PubMed
Google Scholar
Lefkowitz RJ, Shenoy SK: Transduction of receptor signals by beta-arrestins. Science. 2005, 308 (5721): 512-517. 10.1126/science.1109237.
Article
CAS
PubMed
Google Scholar
Shenoy SK, McDonald P, Kohout T, Lefkowitz RJ: Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science. 2001, 294 (5545): 1307-1313. 10.1126/science.1063866.
Article
CAS
PubMed
Google Scholar
Cokic VP, Beleslin-Cokic BB, Noguchi CT, Schechter AN: Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity. Nitric Oxide. 2007, 16 (3): 371-378. 10.1016/j.niox.2007.01.001.
Article
CAS
PubMed
Google Scholar
Steidl U, Kronenwett R, Rohr UP, Fenk R, Kliszewski S, Maercker C, Neubert P, Aivado M, Koch J, Modlich O, Bojar H, Gattermann N, Haas R: Gene expression profiling identifies significant differences between the molecular phenotypes of bone marrow-derived and circulating human CD34+ hematopoietic stem cells. Blood. 2002, 99 (6): 2037-2044. 10.1182/blood.V99.6.2037.
Article
CAS
PubMed
Google Scholar
Ng YY, van Kessel B, Lokhorst HM, Baert MR, van den Burg CM, Bloem AC, Staal FJ: Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem cell activity. J Leukoc Biol. 2004, 75 (2): 314-323.
Article
CAS
PubMed
Google Scholar
Oh IH, Lau A, Eaves CJ: During ontogeny primitive (CD34+CD38-) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts. Blood. 2000, 96 (13): 4160-4168.
CAS
PubMed
Google Scholar
Merryweather-Clarke AT, Atzberger A, Soneji S, Gray N, Clark K, Waugh C, McGowan SJ, Taylor S, Nandi AK, Wood WG, Roberts DJ, Higgs DR, Buckle VJ, Robson KJ: Global gene expression analysis of human erythroid progenitors. Blood. 2011, 117 (13): e96-e108. 10.1182/blood-2010-07-290825.
Article
CAS
PubMed
Google Scholar
Fujishima N, Hirokawa M, Aiba N, Ichikawa Y, Fujishima M, Komatsuda A, Suzuki Y, Kawabata Y, Miura I, Sawada K: Gene expression profiling of human erythroid progenitors by micro-serial analysis of gene expression. Int J Hematol. 2004, 80 (3): 239-245. 10.1532/IJH97.04053.
Article
CAS
PubMed
Google Scholar
Narayan AD, Ersek A, Campbell TA, Colón DM, Pixley JS, Zanjani ED: The effect of hypoxia and stem cell source on haemoglobin switching. Br J Haematol. 2005, 128 (4): 562-570. 10.1111/j.1365-2141.2004.05336.x.
Article
PubMed
Google Scholar
Park JI, Choi HS, Jeong JS, Han JY, Kim IH: Involvement of p38 kinase in hydroxyurea-induced differentiation of K562 cells. Cell Growth Differ. 2001, 12 (9): 481-486.
CAS
PubMed
Google Scholar
Kucukkaya B, Arslan DO, Kan B: Role of G proteins and ERK activation in hemin-induced erythroid differentiation of K562 cells. Life Sci. 2006, 78 (11): 1217-1224. 10.1016/j.lfs.2005.06.041.
Article
CAS
PubMed
Google Scholar
Nishida M, Tanabe S, Maruyama Y, Mangmool S, Urayama K, Nagamatsu Y, Takagahara S, Turner JH, Kozasa T, Kobayashi H, Sato Y, Kawanishi T, Inoue R, Nagao T, Kurose H: G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. J Biol Chem. 2005, 280 (18): 18434-18441.
Article
CAS
PubMed
Google Scholar
Chen CC, Wang JK: p38 but not p44/42 mitogen-activated protein kinase is required for nitric oxide synthase induction mediated by lipopolysaccharide in RAW 264.7 macrophages. Mol Pharmacol. 1999, 55 (3): 481-488.
CAS
PubMed
Google Scholar
Andreeva AV, Vaiskunaite R, Kutuzov MA, Profirovic J, Skidgel RA, Voyno-Yasenetskaya T: Novel mechanisms of G protein-dependent regulation of endothelial nitric-oxide synthase. Mol Pharmacol. 2006, 69 (3): 975-982.
CAS
PubMed
Google Scholar
Shepard LW, Yang M, Xie P, Browning DD, Voyno-Yasenetskaya T, Kozasa T, Ye RD: Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi’s sarcoma-associated herpes virus involve G alpha(13) and RhoA. J Biol Chem. 2001, 276 (49): 45979-45987. 10.1074/jbc.M104783200.
Article
CAS
PubMed
Google Scholar
Addya S, Keller MA, Delgrosso K, Ponte CM, Vadigepalli R, Gonye GE, Surrey S: Erythroid-induced commitment of K562 cells results in clusters of differentially-expressed genes enriched for specific transcription regulatory elements. Physiol Genomics. 2004, 19 (1): 117-130. 10.1152/physiolgenomics.00028.2004.
Article
CAS
PubMed
Google Scholar
Adunyah SE, Chander R, Barner VK, Cooper RS, Copper RS: Regulation of c-jun mRNA expression by hydroxyurea in human K562 cells during erythroid differentiation. Biochim Biophys Acta. 1995, 1263 (2): 123-132. 10.1016/0167-4781(95)00079-V.
Article
PubMed
Google Scholar
Jacobs-Helber SM, Abutin RM, Tian C, Bondurant M, Wickrema A, Sawyer ST: Role of JunB in erythroid differentiation. J Biol Chem. 2002, 277 (7): 4859-4866. 10.1074/jbc.M107243200.
Article
CAS
PubMed
Google Scholar
Amatruda TT, Steele DA, Slepak VZ, Simon MI: G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells. Proc Natl Acad Sci USA. 1991, 88 (13): 5587-5591. 10.1073/pnas.88.13.5587.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wu D, Kuang Y, Wu Y, Jiang H: Selective coupling of beta 2-adrenergic receptor to hematopoietic-specific G proteins. J Biol Chem. 1995, 270 (27): 16008-16010. 10.1074/jbc.270.27.16008.
Article
CAS
PubMed
Google Scholar
Holstein DM, Berg KA, Leeb-Lundberg LM, Olson MS, Saunders C: Calcium-sensing receptor-mediated ERK1/2 activation requires Galphai2 coupling and dynamin-independent receptor internalization. J Biol Chem. 2004, 279 (11): 10060-10069.
Article
CAS
PubMed
Google Scholar
Mardini L, Gasiorek J, Derjuga A, Carrière L, Schranzhofer M, Paw BH, Ponka P, Blank V: Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake. Biochem J. 2010, 432 (1): 145-151. 10.1042/BJ20100541.
Article
CAS
PubMed
Google Scholar
Witt O, Sand K, Pekrun A: Butyrate induced erythroid differentiation of human K562 cells involves inhibition of ERK and activation of p38 MAP kinase-pathways. Blood. 2000, 95 (7): 2391-2396.
CAS
PubMed
Google Scholar
Witt O, Monkemeyer S, Rönndahl G, Erdlenbruch B, Reinhardt D, Kanbach K, Pekrun A: Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. Blood. 2003, 101 (5): 2001-2007. 10.1182/blood-2002-08-2617.
Article
CAS
PubMed
Google Scholar
Choi YH, Lee SN, Aoyagi H, Yamasaki Y, Yoo JY, Park B, Shin DM, Yoon HG, Yoon JH: The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling. J Biol Chem. 2011, 286 (39): 34199-34214. 10.1074/jbc.M111.247684.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ji R, Chou CL, Xu W, Chen XB, Woodward DF, Regan JW: EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway. Mol Pharmacol. 2010, 77 (6): 1025-1036. 10.1124/mol.110.063933.
Article
PubMed Central
CAS
PubMed
Google Scholar
Keefer JR, Schneidereith TA, Mays A, Purvis SH, Dover GJ, Smith KD: Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells. Exp Hematol. 2006, 34 (9): 1151-1161.
Article
CAS
PubMed
Google Scholar
Ikuta T, Ausenda S, Cappellini MD: Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway. Proc Natl Acad Sci USA. 2001, 98 (4): 1847-1852. 10.1073/pnas.98.4.1847.
Article
PubMed Central
CAS
PubMed
Google Scholar
Haby C, Lisovoski F, Aunis D, Zwiller J: Stimulation of the cyclic GMP pathway by NO induces expression of the immediate early genes c-fos and junB in PC12 cells. J Neurochem. 1994, 62 (2): 496-501.
Article
CAS
PubMed
Google Scholar
Kodeboyina S, Balamurugan P, Liu L, Pace BS: cJun modulates Ggamma-globin gene expression via an upstream cAMP response element. Blood Cells Mol Dis. 2010, 44 (1): 7-15. 10.1016/j.bcmd.2009.10.002.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bailey L, Kuroyanagi Y, Franco-Penteado CF, Conran N, Costa FF, Ausenda S, Cappellini MD, Ikuta T: Expression of the gamma-globin gene is sustained by the cAMP-dependent pathway in beta-thalassaemia. Br J Haematol. 2007, 138 (3): 382-395. 10.1111/j.1365-2141.2007.06673.x.
Article
CAS
PubMed
Google Scholar
Browning DD, Windes ND, Ye RD: Activation of p38 mitogen-activated protein kinase by lipopolysaccharide in human neutrophils requires nitric oxide-dependent cGMP accumulation. J Biol Chem. 1999, 274 (1): 537-542. 10.1074/jbc.274.1.537.
Article
CAS
PubMed
Google Scholar
Kim SO, Xu Y, Katz S, Pelech S: Cyclic GMP-dependent and -independent regulation of MAP kinases by sodium nitroprusside in isolated cardiomyocytes. Biochim Biophys Acta. 2000, 1496 (2–3): 277-284.
Article
CAS
PubMed
Google Scholar
Pace BS, Qian XH, Sangerman J, Ofori-Acquah SF, Baliga BS, Han J, Critz SD: p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors. Exp Hematol. 2003, 31 (11): 1089-1096. 10.1016/S0301-472X(03)00235-2.
Article
CAS
PubMed
Google Scholar
Ramakrishnan V, Pace BS: Regulation of γ-globin gene expression involves signaling through the p38 MAPK/CREB1 pathway. Blood Cells Mol Dis. 2011, 47 (1): 12-22. 10.1016/j.bcmd.2011.03.003.
Article
PubMed Central
CAS
PubMed
Google Scholar
Smith RD, Li J, Noguchi CT, Schechter AN: Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. Blood. 2000, 95 (3): 863-869.
CAS
PubMed
Google Scholar
Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, Stoeckert C, Aach J, Ansorge W, Ball CA, Causton HC, Gaasterland T, Glenisson P, Holstege FC, Kim IF, Markowitz V, Matese JC, Parkinson H, Robinson A, Sarkans U, Schulze-Kremer S, Stewart J, Taylor R, Vilo J, Vingron M: Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet. 2001, 29 (4): 365-371. 10.1038/ng1201-365.
Article
CAS
PubMed
Google Scholar
Risinger JI, Maxwell GL, Chandramouli GV, Jazaeri A, Aprelikova O, Patterson T, Berchuck A, Barrett JC: Microarray analysis reveals distinct gene expression profiles among different histologic types of endometrial cancer. Cancer Res. 2003, 63 (1): 6-11.
CAS
PubMed
Google Scholar