Marczynski B, Czuppon AB, Marek W, Reichel G, Baur X: Increased incidence of DNA double-strand breaks and anti-ds DNA antibodies in blood of workers occupationally exposed to asbestos. Hum Exp Toxicol. 1994, 13: 3-9.
Article
CAS
PubMed
Google Scholar
Fatma N, Jain AK, Rahman Q: Frequency of sister chromatid exchange and chromosomal aberrations in asbestos cement workers. Br J Ind Med. 1991, 48: 103-105.
CAS
PubMed Central
PubMed
Google Scholar
Mossman BT, Churg A: Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med. 1998, 157: 1666-1680.
Article
CAS
PubMed
Google Scholar
Shukla A, Ramos-Nino M, Mossman B: Cell signaling and transcription factor activation by asbestos in lung injury and disease. Int J Biochem Cell Biol. 2003, 35: 1198-1209. 10.1016/S1357-2725(02)00315-1.
Article
CAS
PubMed
Google Scholar
Nelson HH, Kelsey KT: The molecular epidemiology of asbestos and tobacco in lung cancer. Oncogene. 2002, 21: 7284-7288. 10.1038/sj.onc.1205804.
Article
CAS
PubMed
Google Scholar
Ramos-Nino ME, Heintz N, Scappoli L, Martinelli M, Land S, Nowak N, Haegens A, Manning B, Manning N, MacPherson M, Stern M, Mossman B: Gene profiling and kinase screening in asbestos-exposed epithelial cells and lungs. Am J Respir Cell Mol Biol. 2003, 29: S51-8.
CAS
PubMed
Google Scholar
Yang H, Bocchetta M, Kroczynska B, Elmishad AG, Chen Y, Liu Z, Bubici C, Mossman BT, Pass HI, Testa JR, Franzoso G, Carbone M: TNF-{alpha} inhibits asbestos-induced cytotoxicity via a NF-{kappa}B-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. PNAS. 2006, 103: 10397-10402. 10.1073/pnas.0604008103.
Article
CAS
PubMed Central
PubMed
Google Scholar
Nymark P, Wikman H, Ruosaari S, Hollmen J, Vanhala E, Karjalainen A, Anttila S, Knuutila S: Identification of specific gene copy number changes in asbestos-related lung cancer. Cancer Res. 2006, 66: 5737-5743. 10.1158/0008-5472.CAN-06-0199.
Article
CAS
PubMed
Google Scholar
Krismann M, Müller KM, Jaworska M, Johnen G: Molecular cytogenetic differences between histological subtypes of malignant mesotheliomas: DNA cytometry and comparative genomic hybridization of 90 cases. J Pathol. 2002, 197: 363-371. 10.1002/path.1128.
Article
CAS
PubMed
Google Scholar
Wikman H, Ruosaari S, Nymark P, Sarhadi VK, Saharinen J, Vanhala E, Karjalainen A, Hollmén J, Knuutila S, Anttila S: Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer. Oncogene. 2007, epub ahead of print-
Google Scholar
Mutsaers SE: The mesothelial cell. Int J Biochem Cell Biol. 2004, 36: 9-16. 10.1016/S1357-2725(03)00242-5.
Article
CAS
PubMed
Google Scholar
Ensemble BioMart. [http://www.ensembl.org/Multi/martview]
Liu JY, Brody AR: Increased TGF-beta1 in the lungs of asbestos-exposed rats and mice: reduced expression in TNF-alpha receptor knockout mice. J Environ Pathol Toxicol Oncol. 2001, 2: 97-108.
Google Scholar
Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM: Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene. 2004, 23: 6672-6676. 10.1038/sj.onc.1207881.
Article
CAS
PubMed
Google Scholar
Ohno M, Miura T, Furuichi M, Tominaga Y, Tsuchimoto D, Sakumi K, Nakabeppu Y: A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome. Genome Res. 2006, 16: 567-575. 10.1101/gr.4769606.
Article
CAS
PubMed Central
PubMed
Google Scholar
Timblin CR, Guthrie GD, Janssen YWM, Walsh ES, Vacek P, Mossman BT: Patterns of c-fos and c-jun proto-oncogene expression, apoptosis, and proliferation in rat pleural mesothelial cells exposed to erionite or asbestos fibers. Toxicology and Applied Pharmacology. 1998, 151: 88-97. 10.1006/taap.1998.8450.
Article
CAS
PubMed
Google Scholar
Vakkila J, Lotze MT: Inflammation and necrosis promote tumour growth. Nat Rev Immunol. 2004, 4: 641-648. 10.1038/nri1415.
Article
CAS
PubMed
Google Scholar
Dai J, Churg A: Relationship of fiber surface iron and active oxygen species to expression of procollagen, PDGF-A, and TGF-{beta}1 in tracheal explants exposed to amosite asbestos. Am J Respir Cell Mol Biol. 2001, 24: 427-435.
Article
CAS
PubMed
Google Scholar
Zhao YL, Piao CQ, Wu LJ, Suzuki M, Hei TK: Differentially expressed genes in asbestos-induced tumorigenic human bronchial epithelial cells: implication for mechanism. Carcinogenesis. 2000, 21: 2005-2010. 10.1093/carcin/21.11.2005.
Article
CAS
PubMed
Google Scholar
Sabo-Attwood T, Ramos-Nino M, Bond J, Butnor KJ, Heintz N, Gruber AD, Steele C, Taatjes DJ, Vacek P, Mossman BT: Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis. Am J Pathol. 2005, 167: 1243-1256.
Article
CAS
PubMed Central
PubMed
Google Scholar
Kahlos K, Soini Y, Säily M, Koistinen P, Kakko S, Pääkkö P, Holmgren A, Kinnula V: Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma. International Journal of Cancer. 2001, 95: 198-204. 10.1002/1097-0215(20010520)95:3<198::AID-IJC1034>3.0.CO;2-F.
Article
CAS
Google Scholar
Schenk H, Klein M, Erdbrugger W, Droge W, Schulze-Osthoff K: Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-{kappa}B and AP-1. PNAS. 1994, 91: 1672-1676. 10.1073/pnas.91.5.1672.
Article
CAS
PubMed Central
PubMed
Google Scholar
Matthews JR, Wakasugi N, Virelizier JL, Yodoi J, Hay RT: Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res. 1992, 20: 3821-3830. 10.1093/nar/20.15.3821.
Article
CAS
PubMed Central
PubMed
Google Scholar
Krick S, Eul BG, Hanze J, Savai R, Grimminger F, Seeger W, Rose F: Role of hypoxia-inducible factor-1{alpha} in hypoxia-induced apoptosis of primary alveolar epithelial type II cells. Am J Respir Cell Mol Biol. 2005, 32: 395-403. 10.1165/rcmb.2004-0314OC.
Article
CAS
PubMed
Google Scholar
Lounsbury KM, Stern M, Taatjes D, Jaken S, Mossman BT: Increased localization and substrate activation of protein kinase C{delta} in lung epithelial cells following exposure to asbestos. Am J Pathol. 2002, 160: 1991-2000.
Article
CAS
PubMed Central
PubMed
Google Scholar
Marsit CJ, Hasegawa M, Hirao T, Kim DH, Aldape K, Hinds PW, Wiencke JK, Nelson HH, Kelsey KT: Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small-cell lung cancer. Cancer Res. 2004, 64: 8702-8707. 10.1158/0008-5472.CAN-04-2558.
Article
CAS
PubMed
Google Scholar
Elferink JG, Ebbenhout JL: Asbestos-induced activation of the respiratory burst in rabbit neutrophils. Res Commun Chem Pathol Pharmacol. 1988, 61: 201-211.
CAS
PubMed
Google Scholar
Gius D, Spitz DR: Redox signaling in cancer biology. Antioxid Redox Signal. 2006, 8: 1249-1252. 10.1089/ars.2006.8.1249.
Article
CAS
PubMed
Google Scholar
Dano L, Guilly MN, Muleris M, Morlier JP, Altmeyer S, Vielh P, El-Naggar AK, Monchaux G, Dutrillaux B, Chevillard S: CGH analysis of radon-induced rat lung tumors indicates similarities with human lung cancers. Genes Chromosomes Cancer. 2000, 29: 1-8. 10.1002/1098-2264(2000)9999:9999<000::AID-GCC1000>3.3.CO;2-S.
Article
CAS
PubMed
Google Scholar
Heintz NH, Janssen YM, Mossman BT: Persistent Induction of c-fos and c-jun Expression by Asbestos. PNAS. 1993, 90: 3299-3303. 10.1073/pnas.90.8.3299.
Article
CAS
PubMed Central
PubMed
Google Scholar
Björkqvist AM, Tammilehto L, Anttila S, Mattson K, Knuutila S: Recurrent DNA copy number changes in 1q, 4q, 6q, 9p, 13q, 14q and 22q detected by comparative genomic hybridization in malignant mesothelioma. Br J Cancer. 1997, 75: 523-527.
Article
PubMed Central
PubMed
Google Scholar
Björkqvist AM, Wolf M, Nordling S, Tammilehto L, Knuuttila A, Kere J, Mattson K, Knuutila S: Deletions at 14q in malignant mesothelioma detected by microsatellite marker analysis. Br J Cancer. 1999, 81: 1111-1115. 10.1038/sj.bjc.6690816.
Article
PubMed Central
PubMed
Google Scholar
Knuuttila A, Jee K, Taskinen E, Wolff H, Knuutila S, Anttila S: Spindle cell tumours of the pleura: a clinical, histological and comparative genomic hybridization analysis of 14 cases. Virchows Archiv. 2006, 448: 135-141. 10.1007/s00428-005-0059-3.
Article
PubMed
Google Scholar
Ascoli V, Aalto Y, Carnovale-Scalzo C, Nardi F, Falzetti D, Mecucci C, Knuutila S: DNA copy number changes in familial malignant mesothelioma. Cancer Genetics and Cytogenetics. 2001, 127: 80-82. 10.1016/S0165-4608(00)00420-9.
Article
CAS
PubMed
Google Scholar
Tiainen M, Tammilehto L, Rautonen J, Tuomi T, Mattson K, Knuutila S: Chromosomal abnormalities and their correlations with asbestos exposure and survival in patients with mesothelioma. Br J Cancer. 1989, 60: 618-626.
Article
CAS
PubMed Central
PubMed
Google Scholar
Pass HI, Liu Z, Wali A, Bueno R, Land S, Lott D, Siddiq F, Lonardo F, Carbone M, Draghici S: Gene expression profiles predict survival and progression of pleural mesothelioma. Clin Cancer Res. 2004, 10: 849-859. 10.1158/1078-0432.CCR-0607-3.
Article
CAS
PubMed
Google Scholar
Kettunen E, Nicholson AG, Nagy B, Wikman H, Seppanen JK, Stjernvall T, Ollikainen T, Kinnula V, Nordling S, Hollmen J, Anttila S, Knuutila S: L1CAM, INP10, P-cadherin, tPA and ITGB4 over-expression in malignant pleural mesotheliomas revealed by combined use of cDNA and tissue microarray. Carcinogenesis. 2005, 26: 17-25. 10.1093/carcin/bgh276.
Article
CAS
PubMed
Google Scholar
Lopez-Rios F, Chuai S, Flores R, Shimizu S, Ohno T, Wakahara K, Illei PB, Hussain S, Krug L, Zakowski MF, Rusch V, Olshen AB, Ladanyi M: Global gene expression profiling of pleural mesotheliomas: overexpression of aurora kinases and P16/CDKN2A deletion as prognostic factors and critical evaluation of microarray-based prognostic prediction. Cancer Res. 2006, 66: 2970-2979. 10.1158/0008-5472.CAN-05-3907.
Article
CAS
PubMed
Google Scholar
Gordon GJ, Rockwell GN, Jensen RV, Rheinwald JG, Glickman JN, Aronson JP, Pottorf BJ, Nitz MD, Richards WG, Sugarbaker DJ, Bueno R: Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling. Am J Pathol. 2005, 166: 1827-1840.
Article
CAS
PubMed Central
PubMed
Google Scholar
Pache JC, Janssen YM, Walsh ES, Quinlan TR, Zanella CL, Low RB, Taatjes DJ, Mossman BT: Increased epidermal growth factor-receptor protein in a human mesothelial cell line in response to long asbestos fibers. Am J Pathol. 1998, 152: 333-340.
CAS
PubMed Central
PubMed
Google Scholar
Perkins RC, Courtney Broaddus V, Shetty S, Hamilton S, Idell S: Asbestos upregulates expression of the urokinase-type plasminogen activator receptor on mesothelial cells. Am J Respir Cell Mol Biol. 1999, 21: 637-646.
Article
CAS
PubMed
Google Scholar
Fung H, Kow YW, Van Houten B, Mossman BT: Patterns of 8-hydroxydeoxyguanosine formation in DNA and indications of oxidative stress in rat and human pleural mesothelial cells after exposure to crocidolite asbestos. Carcinogenesis. 1997, 18: 825-832. 10.1093/carcin/18.4.825.
Article
CAS
PubMed
Google Scholar
Kinnula VL, Linnala A, Viitala E, Linnainmaa K, Virtanen I: Tenascin and fibronectin expression in human mesothelial cells and pleural mesothelioma cell-line cells. Am J Respir Cell Mol Biol. 1998, 19: 445-452.
Article
CAS
PubMed
Google Scholar
Ollikainen T, Puhakka A, Kahlos K, Linnainmaa K, Kinnula VL: Modulation of cell and DNA damage by poly(ADP)ribose polymerase in lung cells exposed to H2O2 or asbestos fibres. Mutat Res/Genetic Toxicology and Environmental Mutagenesis. 2000, 470: 77-84. 10.1016/S1383-5718(00)00093-0.
Article
CAS
Google Scholar
Puhakka A, Ollikainen T, Soini Y, Kahlos K, Saily M, Koistinen P, Paakko P, Linnainmaa K, Kinnula VL: Modulation of DNA single-strand breaks by intracellular glutathione in human lung cells exposed to asbestos fibers. Mutat Res/Genetic Toxicology and Environmental Mutagenesis. 2002, 514: 7-17. 10.1016/S1383-5718(01)00322-9.
Article
CAS
Google Scholar
Kinnula VL, Pietarinen-Runtti P, Raivio K, Kahlos K, Pelin K, Mattson K, Linnainmaa K: Manganese superoxide dismutase in human pleural mesothelioma cell lines. Free Radic Biol Med. 1996, 21: 527-532. 10.1016/0891-5849(96)00049-4.
Article
CAS
PubMed
Google Scholar
Affymetrix I Santa Clara, CA, USA: GeneChip expression analysis: data analysis fundamentals. 2004
Google Scholar
Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP: Summaries of Affymetrix GeneChip probe level data. Nucl Acids Res. 2003, 31: e15-10.1093/nar/gng015.
Article
PubMed Central
PubMed
Google Scholar
Bioconductor. [http://www.bioconductor.org]
Breitling R, Amtmann A, Herzyk P: Iterative Group Analysis (iGA): A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments. BMC Bioinformatics. 2004, 5: 34-10.1186/1471-2105-5-34.
Article
PubMed Central
PubMed
Google Scholar
Gautier L, Cope L, Bolstad BM, Irizarry RA: affy--analysis of Affymetrix GeneChip data at the probe level. Bioinformatics. 2004, 20: 307-315. 10.1093/bioinformatics/btg405.
Article
CAS
PubMed
Google Scholar
Ernst J, Nau GJ, Bar-Joseph Z: Clustering short time series gene expression data. Bioinformatics. 2005, 21: i159-168. 10.1093/bioinformatics/bti1022.
Article
CAS
PubMed
Google Scholar
Korpela M, Hollmen J: Extending an algorithm for clustering gene expression time series. 2006, 120-124.
Google Scholar
Hotelling H: Relations between two sets of variates. Biometrika. 1936, 321-377.
Google Scholar
Wang Q, Fan J, Wang H, Liu S: DNA damage and activation of c-ras in human embryo lung cells exposed to chrysotile and cigarette smoking solution. J Environ Pathol Toxicol Oncol. 2000, 19: 13-19.
PubMed
Google Scholar
Palozza P: Can [beta]-carotene regulate cell growth by a redox mechanism? An answer from cultured cells. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Carotenoids and Dietary Lipids. 2005, 1740: 215-221. 10.1016/j.bbadis.2004.12.008.
Article
CAS
Google Scholar