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6355 result(s) for 'general transcription factors vs specific' within BMC Genomics

Page 12 of 128

  1. Tyrosine kinase 2 (Tyk2), a central component of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling, has major effects on innate immunity and inflammation. Mice lacking Tyk2 are...

    Authors: Claus Vogl, Thomas Flatt, Bernd Fuhrmann, Elisabeth Hofmann, Barbara Wallner, Rita Stiefvater, Pavel Kovarik, Birgit Strobl and Mathias Müller
    Citation: BMC Genomics 2010 11:199
    Content type: Research article Published on:

  2. Flatfish metamorphosis denotes the extraordinary transformation of a symmetric pelagic larva into an asymmetric benthic juvenile. Metamorphosis in vertebrates is driven by thyroid hormones (THs), but how they ...

    Authors: Ricardo N. Alves, Ana S. Gomes, Kurt Stueber, Mbaye Tine, M. A. S. Thorne, H. Smáradóttir, Richard Reinhard, M. S. Clark, Ivar Rønnestad and Deborah M. Power
    Citation: BMC Genomics 2016 17:413
    Content type: Research article Published on:

  3. The global dairy industry is currently facing the challenge of heat stress (HS). Despite the implementation of various measures to mitigate the negative impact of HS on milk production, the cellular response o...

    Authors: Guangsheng Li, Xingtan Yu, Ananda B. Portela Fontoura, Awais Javaid, Víctor Sáinz de la Maza-Escolà, Nia S. Salandy, Susan L. Fubini, Ester Grilli, Joseph. W. McFadden and Jingyue Ellie Duan
    Citation: BMC Genomics 2023 24:410
    Content type: Research Published on:

  4. Spiders (Order Araneae) are essential predators in every terrestrial ecosystem largely because they have evolved potent arsenals of silk and venom. Spider silks are high performance materials made almost entir...

    Authors: Thomas H Clarke, Jessica E Garb, Cheryl Y Hayashi, Robert A Haney, Alexander K Lancaster, Susan Corbett and Nadia A Ayoub
    Citation: BMC Genomics 2014 15:365
    Content type: Research article Published on:

  6. TCP proteins are plant specific transcription factors that play important roles in plant growth and development. Despite the known significance of these transcription factors in general plant development, thei...

    Authors: Chaoqun Chen, Yao Zhang, Yuanfei Chen, Hongxu Chen and Ronggao Gong
    Citation: BMC Genomics 2024 25:3
    Content type: Research Published on:

  7. Morphological evaluation of embryos has been used to screen embryos for transfer. However, the repeatability and accuracy of this method remains low. Thus, evaluation of an embryo’s gene expression signature w...

    Authors: Dessie Salilew-Wondim, Dawit Tesfaye, Franca Rings, Eva Held-Hoelker, Dennis Miskel, Marc-Andre Sirard, Ernst Tholen, Karl Schellander and Michael Hoelker
    Citation: BMC Genomics 2021 22:408
    Content type: Research Published on:

  8. The relative contribution of epigenetic mechanisms to carcinogenesis is not well understood, including the extent to which epigenetic dysregulation and somatic mutations target similar genes and pathways. We h...

    Authors: Jung H Kim, Alla Karnovsky, Vasudeva Mahavisno, Terry Weymouth, Manjusha Pande, Dana C Dolinoy, Laura S Rozek and Maureen A Sartor
    Citation: BMC Genomics 2012 13:526
    Content type: Research article Published on:

  9. Tissue regeneration requires a series of steps, beginning with generation of the necessary cell mass, followed by cell migration into damaged area, and ending with differentiation and integration with surround...

    Authors: Ke’ale W. Louie, Alfonso Saera-Vila, Phillip E. Kish, Justin A. Colacino and Alon Kahana
    Citation: BMC Genomics 2017 18:854
    Content type: Research article Published on:

  10. The Tec-family kinase Itk plays an important role during T-cell activation and function, and controls also conventional versus innate-like T-cell development. We have characterized the transcriptome of Itk-def...

    Authors: K Emelie M Blomberg, Nicole Boucheron, Jessica M Lindvall, Liang Yu, Julia Raberger, Anna Berglöf, Wilfried Ellmeier and CI Edvard Smith
    Citation: BMC Genomics 2009 10:233
    Content type: Research article Published on:

  11. DNA Microarrays are regarded as a valuable tool for basic and applied research in microbiology. However, for many industrially important microorganisms the lack of commercially available microarrays still hamp...

    Authors: Alexandra Graf, Brigitte Gasser, Martin Dragosits, Michael Sauer, Germán G Leparc, Thomas Tüchler, David P Kreil and Diethard Mattanovich
    Citation: BMC Genomics 2008 9:390
    Content type: Research article Published on:

  12. How pathogen genomes evolve to support distinct lifestyles is not well-understood. The oomycete Phytophthora infestans, the potato blight agent, is a largely biotrophic pathogen that feeds from living host cells,...

    Authors: Audrey M. V. Ah-Fong, Jolly Shrivastava and Howard S. Judelson
    Citation: BMC Genomics 2017 18:764
    Content type: Research article Published on:

  13. The soil-dwelling nematode Caenorhabditis elegans serves as a model system to study innate immunity against microbial pathogens. C. elegans have been collected from around the world, where they, presumably, adapt...

    Authors: Patrick Lansdon, Maci Carlson and Brian D. Ackley
    Citation: BMC Genomics 2022 23:229
    Content type: Research Published on:

  14. The American alligator (Alligator mississippiensis) displays temperature-dependent sex determination (TSD), in which incubation temperature during embryonic development determines the sexual fate of the individua...

    Authors: Ryohei Yatsu, Shinichi Miyagawa, Satomi Kohno, Benjamin B. Parrott, Katsushi Yamaguchi, Yukiko Ogino, Hitoshi Miyakawa, Russell H. Lowers, Shuji Shigenobu, Louis J. Guillette Jr. and Taisen Iguchi
    Citation: BMC Genomics 2016 17:77
    Content type: Research article Published on:

  15. Methyl jasmonate (MeJA) has been successfully used as an effective elicitor to enhance production of taxol and other taxanes in cultured Taxus cells. However the mechanism of MeJA-mediated taxane biosynthesis rem...

    Authors: Shu-tao Li, Peng Zhang, Meng Zhang, Chun-hua Fu, Chun-fang Zhao, Yan-shan Dong, An-yuan Guo and Long-jiang Yu
    Citation: BMC Genomics 2012 13:295
    Content type: Research article Published on:

  16. Gene ontology analysis using the microarray database generated in a previous study by this laboratory was used to further evaluate how maternal dietary supplementation with pyridoxine combined with different s...

    Authors: Danyel Bueno Dalto, Stephen Tsoi, Michael K. Dyck and Jean-Jacques Matte
    Citation: BMC Genomics 2018 19:836
    Content type: Research article Published on:

  19. High dose ionizing radiation (IR) induces potent toxic cell effects mediated by either direct DNA damage or the production of reactive oxygen species (ROS). IR-induced modulations in multiple biological proces...

    Authors: Lucian Beer, Rudolf Seemann, Robin Ristl, Adolf Ellinger, Mohammad Mahdi Kasiri, Andreas Mitterbauer, Matthias Zimmermann, Christian Gabriel, Mariann Gyöngyösi, Walter Klepetko, Michael Mildner and Hendrik Jan Ankersmit
    Citation: BMC Genomics 2014 15:814
    Content type: Research article Published on:

  20. Kentucky bluegrass (Poa pratensis L.) is a prominent turfgrass in the cool-season regions, but it is sensitive to salt stress. Previously, a relatively salt tolerant Kentucky bluegrass accession was identified th...

    Authors: B. Shaun Bushman, Keenan L. Amundsen, Scott E. Warnke, Joseph G. Robins and Paul G. Johnson
    Citation: BMC Genomics 2016 17:48
    Content type: Research article Published on:

  21. The secreted Meloidogyne javanica fatty acid- and retinol-binding (FAR) protein Mj-FAR-1 is involved in nematode development and reproduction in host tomato roots. To gain further insight into the role of Mj-FAR-...

    Authors: Ionit Iberkleid, Noa Sela and Sigal Brown Miyara
    Citation: BMC Genomics 2015 16:272
    Content type: Research article Published on:

  22. The goal of these studies was to characterize the transcriptional network regulating changes in gene expression in the remnant liver of the rat after 70% partial hepatectomy (PHx) during the early phase respon...

    Authors: Egle Juskeviciute, Rajanikanth Vadigepalli and Jan B Hoek
    Citation: BMC Genomics 2008 9:527
    Content type: Research article Published on:

  23. Spermatogenesis is a highly regulated and complex process in which DNA methylation plays a crucial role. This study aimed to explore the differential methylation profiles in sperm DNA between patients with ast...

    Authors: Jingdi Zhang, Xiaogang Li, Rongrong Wang, Xinxin Feng, Siyu Wang, Hai Wang, Yutao Wang, Hongjun Li, Yongzhe Li and Ye Guo
    Citation: BMC Genomics 2024 25:602
    Content type: Research Published on:

  24. Organisms from many distinct evolutionary lineages acquired the capacity to enter a dormant state in response to environmental conditions incompatible with maintaining normal life activities. Most studied orga...

    Authors: Tamar Hashimshony, Liron Levin, Andreas C. Fröbius, Nitsan Dahan, Vered Chalifa-Caspi, Reini Hamo, Oshri Gabai-Almog, Idit Blais, Yehuda G. Assaraf and Esther Lubzens
    Citation: BMC Genomics 2024 25:119
    Content type: Research Published on:

  25. Differential RNA-sequencing (dRNA-seq) is indispensable for determination of primary transcriptomes. However, using dRNA-seq data to map transcriptional start sites (TSSs) and promoters genome-wide is a bioinf...

    Authors: Jelena Čuklina, Julia Hahn, Maxim Imakaev, Ulrich Omasits, Konrad U. Förstner, Nikolay Ljubimov, Melanie Goebel, Gabriella Pessi, Hans-Martin Fischer, Christian H. Ahrens, Mikhail S. Gelfand and Elena Evguenieva-Hackenberg
    Citation: BMC Genomics 2016 17:302
    Content type: Research article Published on:

  26. The cultivated bread wheat (Triticum aestivum L.) possesses unique flour quality, which can be processed into many end-use food products such as bread, pasta, chapatti (unleavened flat bread), biscuit, etc. The p...

    Authors: Anuradha Singh, Shrikant Mantri, Monica Sharma, Ashok Chaudhury, Rakesh Tuli and Joy Roy
    Citation: BMC Genomics 2014 15:29
    Content type: Research article Published on:

  27. Werner Syndrome (WS) is a rare disorder characterized by the premature onset of a number of age-related diseases. The gene responsible for WS encodes a DNA helicase/exonuclease protein believed to affect diffe...

    Authors: Alexandra Dallaire, Sophie Proulx, Martin J Simard and Michel Lebel
    Citation: BMC Genomics 2014 15:940
    Content type: Research article Published on:

  28. Multiple infection sources for enterohemorrhagic Escherichia coli O157:H7 (EHEC) are known, including animal products, fruit and vegetables. The ecology of this pathogen outside its human host is largely unknown ...

    Authors: Richard Landstorfer, Svenja Simon, Steffen Schober, Daniel Keim, Siegfried Scherer and Klaus Neuhaus
    Citation: BMC Genomics 2014 15:353
    Content type: Research article Published on:

  29. Bifidobacterium breve represents a common member of the infant gut microbiota and its presence in the gut has been associated with host well being. For this reason it is relevant to in...

    Authors: Francesca Bottacini, Aldert Zomer, Christian Milani, Chiara Ferrario, Gabriele Andrea Lugli, Muireann Egan, Marco Ventura and Douwe van Sinderen
    Citation: BMC Genomics 2017 18:991
    Content type: Research article Published on:

  30. It has been reported that nitric oxide (NO) could ameliorate cadmium (Cd) toxicity in tall fescue; however, the underlying mechanisms of NO mediated Cd detoxification are largely unknown. In this study, we inv...

    Authors: Huihui Zhu, Honglian Ai, Zhengrong Hu, Dongyun Du, Jie Sun, Ke Chen and Liang Chen
    Citation: BMC Genomics 2020 21:601
    Content type: Research article Published on:

  32. Rice (Oryza sativa) is one of the most important cereal crops, providing food for more than half of the world’s population. However, grain yields are challenged by various abiotic stresses such as drought, fertil...

    Authors: Jun Yang, Xiaorong Chen, Changlan Zhu, Xiaosong Peng, Xiaopeng He, Junru Fu, Linjuan Ouyang, Jianmin Bian, Lifang Hu, Xiaotang Sun, Jie Xu and Haohua He
    Citation: BMC Genomics 2015 16:959
    Content type: Research article Published on:

  33. The epithelial-to-mesenchymal transition is an important mechanism in cancer metastasis. Although transcription factors including SNAIL, SLUG, and TWIST1 regulate the epithelial-to-mesenchymal transition, othe...

    Authors: Haiyun Wang, Clifford A Meyer, Teng Fei, Gang Wang, Fan Zhang and X Shirley Liu
    Citation: BMC Genomics 2013 14:680
    Content type: Research article Published on:

  34. Fruit ripening in Prunus persica melting varieties involves several physiological changes that have a direct impact on the fruit organoleptic quality and storage potential. By studying the proteomic differences b...

    Authors: Ricardo Nilo-Poyanco, Carol Moraga, Gianfranco Benedetto, Ariel Orellana and Andrea Miyasaka Almeida
    Citation: BMC Genomics 2021 22:17
    Content type: Research article Published on:

  35. Successful social behavior requires real-time integration of information about the environment, internal physiology, and past experience. The molecular substrates of this integration are poorly understood, but...

    Authors: Austin T. Hilliard, Dan Xie, Zhihai Ma, Michael P. Snyder and Russell D. Fernald
    Citation: BMC Genomics 2019 20:699
    Content type: Research article Published on:

  36. Establishment of DNA methylation (DNAme) patterns is essential for balanced multi-lineage cellular differentiation, but exactly how these patterns drive cellular phenotypes is unclear. While > 80% of CpG sites...

    Authors: Timothy J. Scott, Tyler J. Hansen, Evonne McArthur and Emily Hodges
    Citation: BMC Genomics 2023 24:623
    Content type: Research Published on:

  37. MicroRNAs (miRNAs) are important post-transcriptional gene regulators controlling cellular lineage specification and differentiation during embryonic development, including the gastrointestinal system. However...

    Authors: Yu-Han Hung, Meghan Capeling, Jonathan W. Villanueva, Matt Kanke, Michael T. Shanahan, Sha Huang, Rebecca Cubitt, Vera D. Rinaldi, John C. Schimenti, Jason R. Spence and Praveen Sethupathy
    Citation: BMC Genomics 2023 24:641
    Content type: Research Published on:

  38. Age-related resistance (ARR) is a developmentally regulated phenomenon conferring resistance to pathogens or pests. Although ARR has been observed in several host-pathogen systems, the underlying mechanisms ar...

    Authors: Ben N. Mansfeld, Marivi Colle, Chunqiu Zhang, Ying-Chen Lin and Rebecca Grumet
    Citation: BMC Genomics 2020 21:628
    Content type: Research article Published on:

  39. To reduce costs of rearing replacement heifers, researchers have focused on decreasing age at breeding and first calving. To increase returns upon initiation of lactation the focus has been on increasing mamma...

    Authors: M. Vailati-Riboni, R. E. Bucktrout, S. Zhan, A. Geiger, J. C. McCann, R. M. Akers and J. J. Loor
    Citation: BMC Genomics 2018 19:900
    Content type: Research article Published on:

  40. Mutations in the gene encoding thymidine kinase 2 (TK2) result in the myopathic form of mitochondrial DNA depletion syndrome which is a mitochondrial encephalomyopathy presenting in children. In order to unvei...

    Authors: Susana Graciela Kalko, Sonia Paco, Cristina Jou, Maria Angels Rodríguez, Marija Meznaric, Mihael Rogac, Maja Jekovec-Vrhovsek, Monica Sciacco, Maurizio Moggio, Gigliola Fagiolari, Boel De Paepe, Linda De Meirleir, Isidre Ferrer, Manel Roig-Quilis, Francina Munell, Julio Montoya…
    Citation: BMC Genomics 2014 15:91
    Content type: Research article Published on:

  42. Parts of Europe and the United States have witnessed dramatic losses in commercially managed honey bees over the past decade to what is considered an unsustainable extent. The large-scale loss of bees has cons...

    Authors: Lindsay Rutter, Jimena Carrillo-Tripp, Bryony C. Bonning, Dianne Cook, Amy L. Toth and Adam G. Dolezal
    Citation: BMC Genomics 2019 20:412
    Content type: Research article Published on:

  43. Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Although p38 SAPK signalling is known to participate in the regulation of ge...

    Authors: Isabel Ferreiro, Manel Joaquin, Abul Islam, Gonzalo Gomez-Lopez, Montserrat Barragan, Luís Lombardía, Orlando Domínguez, David G Pisano, Nuria Lopez-Bigas, Angel R Nebreda and Francesc Posas
    Citation: BMC Genomics 2010 11:144
    Content type: Research article Published on:

  44. Microarrays offer a powerful tool for diverse applications plant biology and crop improvement. Recently, two comprehensive assemblies of cotton ESTs were constructed based on three Gossypium species. Using these ...

    Authors: Joshua A Udall, Lex E Flagel, Foo Cheung, Andrew W Woodward, Ran Hovav, Ryan A Rapp, Jordan M Swanson, Jinsuk J Lee, Alan R Gingle, Dan Nettleton, Christopher D Town, Z Jeffrey Chen and Jonathan F Wendel
    Citation: BMC Genomics 2007 8:81
    Content type: Methodology article Published on:

  45. The developmental transition between the late fetus and a newborn animal is associated with profound changes in skeletal muscle function as it adapts to the new physiological demands of locomotion and postural...

    Authors: Keren Byrne, Tony Vuocolo, Cedric Gondro, Jason D White, Noelle E Cockett, Tracy Hadfield, Christopher A Bidwell, Jolena N Waddell and Ross L Tellam
    Citation: BMC Genomics 2010 11:378
    Content type: Research article Published on:

  46. In response to pathogen attack, grapevine synthesizes phytoalexins belonging to the family of stilbenes. Grapevine cell cultures represent a good model system for studying the basic mechanisms of plant respons...

    Authors: Anita Zamboni, Pamela Gatto, Alessandro Cestaro, Stefania Pilati, Roberto Viola, Fulvio Mattivi, Claudio Moser and Riccardo Velasco
    Citation: BMC Genomics 2009 10:363
    Content type: Research article Published on:

  47. Coupling the control of expression stochasticity (noise) to the ability of expression change (plasticity) can alter gene function and influence adaptation. A number of factors, such as transcription re-initiat...

    Authors: Djordje Bajić and Juan F Poyatos
    Citation: BMC Genomics 2012 13:343
    Content type: Research article Published on:

  48. The ever-increasing prevalence of diabetes and associated comorbidities serves to highlight the necessity of biologically relevant small-animal models to investigate its etiology, pathology and treatment. Alth...

    Authors: Angela Inglis, Rosario Ubungen, Sarah Farooq, Princess Mata, Jennifer Thiam, Soad Saleh, Sherin Shibin, Futwan A. Al-Mohanna and Kate S. Collison
    Citation: BMC Genomics 2021 22:180
    Content type: Research article Published on:

  49. Perilla frutescens is well known for its high α-linolenic acid (ALA) accumulation in seeds and medicinal values as well as a source of edible and general-purpose oils. However, the regulatory mechanisms of the bi...

    Authors: BingNan Liao, YouJin Hao, JunXing Lu, HuiYang Bai, Li Guan and Tao Zhang
    Citation: BMC Genomics 2018 19:213
    Content type: Research article Published on:

  50. Contemporary coral reef research has firmly established that a genomic approach is urgently needed to better understand the effects of anthropogenic environmental stress and global climate change on coral holo...

    Authors: Walter C Dunlap, Antonio Starcevic, Damir Baranasic, Janko Diminic, Jurica Zucko, Ranko Gacesa, Madeleine J H van Oppen, Daslav Hranueli, John Cullum and Paul F Long
    Citation: BMC Genomics 2013 14:509
    Content type: Database Published on:

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