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  1. MicroRNAs exist widely in viruses, plants and animals. As endogenous small non-coding RNAs, miRNAs regulate a variety of biological processes. Tissue miRNA expression studies have discovered numerous functions...

    Authors: Nan Wu, Qing Zhu, Binlong Chen, Jian Gao, Zhongxian Xu and Diyan Li
    Citation: BMC Genomics 2017 18:255
    Content type: Research article Published on:

  2. Transthyretin (TTR) amyloidosis is a hereditary disease with a complex genotype-phenotype correlation. We conducted a literature survey to define the clinical landscape of TTR amyloidosis across populations wo...

    Authors: Andrea Iorio, Flavio De Angelis, Marco Di Girolamo, Marco Luigetti, Luca G. Pradotto, Anna Mazzeo, Sabrina Frusconi, Filomena My, Dario Manfellotto, Maria Fuciarelli and Renato Polimanti
    Citation: BMC Genomics 2017 18:254
    Content type: Research article Published on:

  3. It was recently reported that dairy cows fed a polyphenol-rich grape seed and grape marc meal extract (GSGME) during the transition period had an increased milk yield, but the underlying reasons remained uncle...

    Authors: Denise K. Gessner, Anne Winkler, Christian Koch, Georg Dusel, Gerhard Liebisch, Robert Ringseis and Klaus Eder
    Citation: BMC Genomics 2017 18:253
    Content type: Research article Published on:

  4. Vitamin C (vit C) is an essential dietary nutrient, which is a potent antioxidant, a free radical scavenger and functions as a cofactor in many enzymatic reactions. Vit C is also considered to enhance the immu...

    Authors: Sakshi Dhingra Batra, Malobi Nandi, Kriti Sikri and Jaya Sivaswami Tyagi
    Citation: BMC Genomics 2017 18:252
    Content type: Research article Published on:

  6. DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not be...

    Authors: Jesper L. V. Maag, Dominik C. Kaczorowski, Debabrata Panja, Timothy J. Peters, Clive R. Bramham, Karin Wibrand and Marcel E. Dinger
    Citation: BMC Genomics 2017 18:250
    Content type: Research article Published on:

  7. The order Picornavirales represents a diverse group of positive-stranded RNA viruses with small non-enveloped icosahedral virions. Recently, bats have been identified as an important reservoir of several highly p...

    Authors: Claude Kwe Yinda, Roland Zell, Ward Deboutte, Mark Zeller, Nádia Conceição-Neto, Elisabeth Heylen, Piet Maes, Nick J. Knowles, Stephen Mbigha Ghogomu, Marc Van Ranst and Jelle Matthijnssens
    Citation: BMC Genomics 2017 18:249
    Content type: Research article Published on:

  8. Genetic studies of human lung function and Chronic Obstructive Pulmonary Disease have identified a highly significant and reproducible signal on 4q24. It remains unclear which of the two candidate genes within...

    Authors: Alexander K. Kheirallah, Cornelia H. de Moor, Alen Faiz, Ian Sayers and Ian P. Hall
    Citation: BMC Genomics 2017 18:248
    Content type: Research article Published on:

  10. Date palm, as one of the most important fruit crops in North African and West Asian countries including Oman, is facing serious growth problems due to salinity, arising from persistent use of saline water for ...

    Authors: Mahmoud W. Yaish, Himanshu V. Patankar, Dekoum V. M. Assaha, Yun Zheng, Rashid Al-Yahyai and Ramanjulu Sunkar
    Citation: BMC Genomics 2017 18:246
    Content type: Research article Published on:

  11. Huperzia serrata (H. serrata) is an economically important traditional Chinese herb with the notably medicinal value. As a representative member of the Lycopodiaceae family, the H. ser...

    Authors: Mengquan Yang, Wenjing You, Shiwen Wu, Zhen Fan, Baofu Xu, Mulan Zhu, Xuan Li and Youli Xiao
    Citation: BMC Genomics 2017 18:245
    Content type: Research article Published on:

  12. Animal’s efficiency in converting feed into lean gain is a critical issue for the profitability of meat industries. This study aimed to describe shared and specific molecular responses in different tissues of ...

    Authors: Florence Gondret, Annie Vincent, Magalie Houée-Bigot, Anne Siegel, Sandrine Lagarrigue, David Causeur, Hélène Gilbert and Isabelle Louveau
    Citation: BMC Genomics 2017 18:244
    Content type: Research article Published on:

  13. Although tumor-associated macrophages (TAMs) are essential for cancer progression, connections between different clinical outcomes and transcriptional networks have not been reported. We have addressed this is...

    Authors: Till Adhikary, Annika Wortmann, Florian Finkernagel, Sonja Lieber, Andrea Nist, Thorsten Stiewe, Uwe Wagner, Sabine Müller-Brüsselbach, Silke Reinartz and Rolf Müller
    Citation: BMC Genomics 2017 18:243
    Content type: Research article Published on:

  15. Gut microbial colonization and development of immune competence are intertwined and are influenced by early-life nutritional, environmental, and management factors. Perturbation of the gut microbiome at young ...

    Authors: Dirkjan Schokker, Alfons J. M. Jansman, Gosse Veninga, Naomi de Bruin, Stephanie A. Vastenhouw, Freddy M. de Bree, Alex Bossers, Johanna M. J. Rebel and Mari A. Smits
    Citation: BMC Genomics 2017 18:241
    Content type: Research article Published on:

  17. We recently identified 700 genes whose expression levels were predictive of chronic lymphocytic leukemia (CLL) in a genome-wide gene expression analysis of prediagnostic blood from future cases and matched con...

    Authors: Jelle Vlaanderen, Max Leenders, Marc Chadeau-Hyam, Lützen Portengen, Soterios A. Kyrtopoulos, Ingvar A. Bergdahl, Ann-Sofie Johansson, Dennie D.G.A.J. Hebels, Theo M.C.M. de Kok, Paolo Vineis and Roel C.H. Vermeulen
    Citation: BMC Genomics 2017 18:239
    Content type: Research article Published on:

  18. The oral cavity is inhabited by complex microbial communities forming biofilms that can cause caries and periodontitis. Cell-cell communication might play an important role in modulating the physiologies of in...

    Authors: Szymon P. Szafrański, Zhi-Luo Deng, Jürgen Tomasch, Michael Jarek, Sabin Bhuju, Manfred Rohde, Helena Sztajer and Irene Wagner-Döbler
    Citation: BMC Genomics 2017 18:238
    Content type: Research article Published on:

  21. Authors: Hisham Abdelrahman, Mohamed ElHady, Acacia Alcivar-Warren, Standish Allen, Rafet Al-Tobasei, Lisui Bao, Ben Beck, Harvey Blackburn, Brian Bosworth, John Buchanan, Jesse Chappell, William Daniels, Sheng Dong, Rex Dunham, Evan Durland, Ahmed Elaswad…
    Citation: BMC Genomics 2017 18:235
    Content type: Erratum Published on:

    The original article was published in BMC Genomics 2017 18:191

  22. We report a statistical study to find correspondence of D. melanogaster and C. elegans developmental stages based on alternative splicing (AS) characteristics of conserved cassette exons using modENCODE RNA-seq d...

    Authors: Ruiqi Gao and Jingyi Jessica Li
    Citation: BMC Genomics 2017 18:234
    Content type: Research article Published on:

  23. B. napus (oilseed) is an important source of edible vegetable oil, and its nutritional and economic value is determined by its fatty acid composition and content.

    Authors: Cunmin Qu, Ledong Jia, Fuyou Fu, Huiyan Zhao, Kun Lu, Lijuan Wei, Xinfu Xu, Ying Liang, Shimeng Li, Rui Wang and Jiana Li
    Citation: BMC Genomics 2017 18:232
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2017 18:377

  24. Human papillomavirus (HPV) is the carcinogen of almost all invasive cervical cancer and a major cause of oral and other anogenital malignancies. HPV genotyping by dideoxy (Sanger) sequencing is currently the r...

    Authors: Jane Shen-Gunther, Yufeng Wang, Zhao Lai, Graham M. Poage, Luis Perez and Tim H. M. Huang
    Citation: BMC Genomics 2017 18:231
    Content type: Research article Published on:

  25. Due to its variegated and colorful leaves, ornamental kale (Brassica oleracea L. var. acephala) has become a popular ornamental plant. In this study, we report the fine mapping and analysis of a candidate purple ...

    Authors: Xiao-ping Liu, Bao-zhen Gao, Feng-qing Han, Zhi-yuan Fang, Li-mei Yang, Mu Zhuang, Hong-hao Lv, Yu-mei Liu, Zhan-sheng Li, Cheng-cheng Cai, Hai-long Yu, Zhi-yuan Li and Yang-yong Zhang
    Citation: BMC Genomics 2017 18:230
    Content type: Research article Published on:

  26. The detection of signatures of selection has the potential to elucidate the identities of genes and mutations associated with phenotypic traits important for livestock species. It is also very relevant to inve...

    Authors: Luiz F. Brito, James W. Kijas, Ricardo V. Ventura, Mehdi Sargolzaei, Laercio R. Porto-Neto, Angela Cánovas, Zeny Feng, Mohsen Jafarikia and Flávio S. Schenkel
    Citation: BMC Genomics 2017 18:229
    Content type: Research article Published on:

  27. MicroRNAs (miRNAs) have great potential serving as tumor biomarkers and therapeutic targets. As the rapid development of high-throughput experimental technology, gene expression experiments have become more an...

    Authors: Yang Yang, Ning Huang, Luning Hao and Wei Kong
    Citation: BMC Genomics 2017 18(Suppl 2):210
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  28. Active modules are connected regions in biological network which show significant changes in expression over particular conditions. The identification of such modules is important since it may reveal the regul...

    Authors: Dong Li, Zhisong Pan, Guyu Hu, Zexuan Zhu and Shan He
    Citation: BMC Genomics 2017 18(Suppl 2):209
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  29. Standard graphical tools for whole genome comparison require a reference genome. However, any reference is also subject to annotation biases and rearrangements, and may not serve as the standard except for tho...

    Authors: Ipputa Tada, Yasuhiro Tanizawa and Masanori Arita
    Citation: BMC Genomics 2017 18(Suppl 2):208
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  30. Inbreeding mating has been widely accepted as the key mechanism to enhance homozygosity which normally will decrease the fitness of the population. Although this result has been validated by a large amount of ...

    Authors: Shuhao Sun, Fima Klebaner and Tianhai Tian
    Citation: BMC Genomics 2017 18(Suppl 2):196
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  31. The mass spectrometry based technical pipeline has provided a high-throughput, high-sensitivity and high-resolution platform for post-genomic biology. Varied models and algorithms are implemented by different ...

    Authors: Xiao-dong Feng, Li-wei Li, Jian-hong Zhang, Yun-ping Zhu, Cheng Chang, Kun-xian Shu and Jie Ma
    Citation: BMC Genomics 2017 18(Suppl 2):143
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  32. In proteomics, batch effects are technical sources of variation that confounds proper analysis, preventing effective deployment in clinical and translational research.

    Authors: Wilson Wen Bin Goh and Limsoon Wong
    Citation: BMC Genomics 2017 18(Suppl 2):142
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  33. The increasing studies have been conducted using whole genome DNA methylation detection as one of the most important part of epigenetics research to find the significant relationships among DNA methylation and...

    Authors: Shaoliang Peng, Shunyun Yang, Ming Gao, Xiangke Liao, Jie Liu, Canqun Yang, Chengkun Wu and Wenqiang Yu
    Citation: BMC Genomics 2017 18(Suppl 2):134
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  34. Detection of gene-gene interaction (GGI) is a key challenge towards solving the problem of missing heritability in genetics. The multifactor dimensionality reduction (MDR) method has been widely studied for de...

    Authors: Sangseob Leem and Taesung Park
    Citation: BMC Genomics 2017 18(Suppl 2):115
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  35. A key step in microbiome sequencing analysis is read assignment to taxonomic units. This is often performed using one of four taxonomic classifications, namely SILVA, RDP, Greengenes or NCBI. It is unclear how...

    Authors: Monika Balvočiūtė and Daniel H. Huson
    Citation: BMC Genomics 2017 18(Suppl 2):114
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  36. The broad heterogeneity of antigen-antibody interactions brings tremendous challenges to the design of a widely applicable learning algorithm to identify conformational B-cell epitopes. Besides the intrinsic h...

    Authors: Jing Ren, Jiangning Song, John Ellis and Jinyan Li
    Citation: BMC Genomics 2017 18(Suppl 2):113
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  37. Emerging evidence indicates that plant miRNAs can present within human circulating system through dietary intake and regulate human gene expression. Hence we deduced that comestible plants miRNAs can be identi...

    Authors: Yu-Chen Liu, Wen Liang Chen, Wei-Hsiang Kung and Hsien-Da Huang
    Citation: BMC Genomics 2017 18(Suppl 2):112
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  38. Over the past two decades, phylogenetic networks have been studied to model reticulate evolutionary events. The relationships among phylogenetic networks, phylogenetic trees and clusters serve as the basis for...

    Authors: Bingxin Lu, Louxin Zhang and Hon Wai Leong
    Citation: BMC Genomics 2017 18(Suppl 2):111
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  39. Cancer is a complex disease driven by somatic genomic alterations (SGAs) that perturb signaling pathways and consequently cellular function. Identifying patterns of pathway perturbations would provide insights...

    Authors: Vicky Chen, John Paisley and Xinghua Lu
    Citation: BMC Genomics 2017 18(Suppl 2):105
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  40. Computational drug design approaches are important for shortening the time and reducing the cost for drug discovery and development. Among these methods, molecular docking and quantitative structure activity r...

    Authors: Hui-Hui Hsu, Yen-Chao Hsu, Li-Jen Chang and Jinn-Moon Yang
    Citation: BMC Genomics 2017 18(Suppl 2):104
    Content type: Research Published on:

    This article is part of a Supplement: Volume 18 Supplement 2

  43. The availability of the peach genome sequence has fostered relevant research in peach and related Prunus species enabling the identification of genes underlying important horticultural traits as well as the devel...

    Authors: Ignazio Verde, Jerry Jenkins, Luca Dondini, Sabrina Micali, Giulia Pagliarani, Elisa Vendramin, Roberta Paris, Valeria Aramini, Laura Gazza, Laura Rossini, Daniele Bassi, Michela Troggio, Shengqiang Shu, Jane Grimwood, Stefano Tartarini, Maria Teresa Dettori…
    Citation: BMC Genomics 2017 18:225
    Content type: Research article Published on:

  44. During a substantial elevation in scarlet fever (SF) notifications in 2014 a national genomic study was undertaken of Streptococcus pyogenes (Group A Streptococci, GAS) isolates from patients with SF with compari...

    Authors: Victoria Chalker, Aleksey Jironkin, Juliana Coelho, Ali Al-Shahib, Steve Platt, Georgia Kapatai, Roger Daniel, Chenchal Dhami, Marisa Laranjeira, Timothy Chambers, Rebecca Guy, Theresa Lamagni, Timothy Harrison, Meera Chand, Alan P. Johnson and Anthony Underwood
    Citation: BMC Genomics 2017 18:224
    Content type: Research article Published on:

  45. Microalgal triglyceride (TAG) synthesis has attracted considerable attention. Particular emphasis has been put towards characterizing the algal homologs of the canonical rate-limiting enzymes, diacylglycerol a...

    Authors: Carolina Bagnato, María B. Prados, Gisela R. Franchini, Natalia Scaglia, Silvia E. Miranda and María V. Beligni
    Citation: BMC Genomics 2017 18:223
    Content type: Research article Published on:

  46. Segmental duplications are an abundant source for novel gene functions and evolutionary adaptations. This mechanism of generating novelty was very active during the evolution of primates particularly in the hu...

    Authors: Cemalettin Bekpen, Sven Künzel, Chen Xie, Muthukrishnan Eaaswarkhanth, Yen-Lung Lin, Omer Gokcumen, Cezmi A. Akdis and Diethard Tautz
    Citation: BMC Genomics 2017 18:222
    Content type: Research article Published on:

  47. The decision for a bud to grow into a branch is a key regulatory process affecting plant architecture. In order to study molecular processes regulating axillary bud outgrowth in the model plant garden pea (Pisum ...

    Authors: Stephanie C. Kerr, Federico Gaiti, Christine A. Beveridge and Milos Tanurdzic
    Citation: BMC Genomics 2017 18:221
    Content type: Research article Published on:

  48. As a typical geocarpic plant, peanut embryogenesis and pod development are complex processes involving many gene regulatory pathways and controlled by appropriate hormone level. MicroRNAs (miRNAs) are small no...

    Authors: Chao Gao, Pengfei Wang, Shuzhen Zhao, Chuanzhi Zhao, Han Xia, Lei Hou, Zheng Ju, Ye Zhang, Changsheng Li and Xingjun Wang
    Citation: BMC Genomics 2017 18:220
    Content type: Research article Published on:

  49. Organisms typically face infection by diverse pathogens, and hosts are thought to have developed specific responses to each type of pathogen they encounter. The advent of transcriptomics now makes it possible ...

    Authors: Vincent Doublet, Yvonne Poeschl, Andreas Gogol-Döring, Cédric Alaux, Desiderato Annoscia, Christian Aurori, Seth M. Barribeau, Oscar C. Bedoya-Reina, Mark J. F. Brown, James C. Bull, Michelle L. Flenniken, David A. Galbraith, Elke Genersch, Sebastian Gisder, Ivo Grosse, Holly L. Holt…
    Citation: BMC Genomics 2017 18:207
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2017 18:256

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BMC Genomics

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