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6355 result(s) for 'general transcription factors vs specific' within BMC Genomics

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  1. There are very few molecular genetic tools available to study the apicomplexan parasite Cryptosporidium parvum. The organism is not amenable to continuous in vitro cultivation or transfection, and purification of...

    Authors: Jenna Oberstaller, Sandeep J Joseph and Jessica C Kissinger
    Citation: BMC Genomics 2013 14:516
    Content type: Research article Published on:

  2. Alterations in brain-derived neurotrophic factor (BDNF) gene expression contribute to serious pathologies such as depression, epilepsy, cancer, Alzheimer's, Huntington and Parkinson's disease. Therefore, explorin...

    Authors: Tamara Aid-Pavlidis, Pavlos Pavlidis and Tõnis Timmusk
    Citation: BMC Genomics 2009 10:420
    Content type: Research article Published on:

  3. Many species of bivalves exhibit a unique system of mtDNA transmission named Doubly Uniparental Inheritance (DUI). Under this system, species have two distinct, sex-linked mitochondrial genomes: the M-type mtD...

    Authors: Alyssa Mitchell, Davide Guerra, Donald Stewart and Sophie Breton
    Citation: BMC Genomics 2016 17:597
    Content type: Research article Published on:

  4. Mesenchymal Stem Cells are ideal seed cells for tissue repair and cell therapy and have promising applications in regenerative medicine and tissue engineering. Using Platelet-Rich Plasma as an adjuvant to crea...

    Authors: Pengxiu Dai, Yi Wu, Yaxin Gao, Mengnan Li, Mingde Zhu, Haojie Xu, Xiancheng Feng, Yaping Jin and Xinke Zhang
    Citation: BMC Genomics 2024 25:564
    Content type: Research Published on:

  5. Feathers have diverse forms with hierarchical branching patterns and are an excellent model for studying the development and evolution of morphological traits. The complex structure of feathers allows for vari...

    Authors: Chen Siang Ng, Chih-Kuan Chen, Wen-Lang Fan, Ping Wu, Siao-Man Wu, Jiun-Jie Chen, Yu-Ting Lai, Chi-Tang Mao, Mei-Yeh Jade Lu, Di-Rong Chen, Ze-Shiang Lin, Kai-Jung Yang, Yuan-An Sha, Tsung-Che Tu, Chih-Feng Chen, Cheng-Ming Chuong…
    Citation: BMC Genomics 2015 16:756
    Content type: Research article Published on:

  6. The transformation of a developing epithelium into an adult structure is a complex process, which often involves coordinated changes in cell proliferation, metabolism, adhesion, and shape. To identify genetic ...

    Authors: David D O’Keefe, Sean R Thomas, Kelsey Bolin, Ellen Griggs, Bruce A Edgar and Laura A Buttitta
    Citation: BMC Genomics 2012 13:498
    Content type: Research article Published on:

  7. Although many studies have been done to reveal artificial selection signatures in commercial and indigenous chickens, a limited number of genes have been linked to specific traits. To identify more trait-relat...

    Authors: Siwen Wu, Tengfei Dou, Kun Wang, Sisi Yuan, Shixiong Yan, Zhiqiang Xu, Yong Liu, Zonghui Jian, Jingying Zhao, Rouhan Zhao, Hao Wu, Dahai Gu, Lixian Liu, Qihua Li, Dong-Dong Wu, Changrong Ge…
    Citation: BMC Genomics 2024 25:428
    Content type: Research Published on:

  8. The thyroid is the earliest endocrine structure to appear during human development, and thyroid hormones are necessary for proper organism development, in particular for the nervous system and heart, normal gr...

    Authors: Lorenza Vitale, Allison Piovesan, Francesca Antonaros, Pierluigi Strippoli, Maria Chiara Pelleri and Maria Caracausi
    Citation: BMC Genomics 2017 18:739
    Content type: Research article Published on:

  9. The common littoral shrimp Palaemon serratus is an economically important decapod resource in some European communities. Aquaculture practices prevent the genetic deterioration of wild stocks caused by overfishin...

    Authors: Inés González-Castellano, Chiara Manfrin, Alberto Pallavicini and Andrés Martínez-Lage
    Citation: BMC Genomics 2019 20:757
    Content type: Research article Published on:

  10. Environmental factors during perinatal development may influence developmental plasticity and disease susceptibility via alterations to the epigenome. Developmental exposure to the endocrine active compound, b...

    Authors: Jung H Kim, Maureen A Sartor, Laura S Rozek, Christopher Faulk, Olivia S Anderson, Tamara R Jones, Muna S Nahar and Dana C Dolinoy
    Citation: BMC Genomics 2014 15:30
    Content type: Research article Published on:

  12. Saccharomyces cerevisiae and Pichia pastoris are two of the most relevant microbial eukaryotic platforms for the production of recombinant proteins. Their known genome sequences enabled several transcriptomic pro...

    Authors: Kristin Baumann, Laura Dato, Alexandra B Graf, Gianni Frascotti, Martin Dragosits, Danilo Porro, Diethard Mattanovich, Pau Ferrer and Paola Branduardi
    Citation: BMC Genomics 2011 12:218
    Content type: Research article Published on:

  13. Pitayas are currently attracting considerable interest as a tropical fruit with numerous health benefits. However, as a long-day plant, pitaya plants cannot flower in the winter season from November to April i...

    Authors: Rui Xiong, Chengli Liu, Min Xu, Shuang-shuang Wei, Jia-quan Huang and Hua Tang
    Citation: BMC Genomics 2020 21:329
    Content type: Research article Published on:

  14. Nutritional symbioses play a central role in insects’ adaptation to specialized diets and in their evolutionary success. The obligatory symbiosis between the pea aphid, Acyrthosiphon pisum, and the bacterium, Buc...

    Authors: Andréane Rabatel, Gérard Febvay, Karen Gaget, Gabrielle Duport, Patrice Baa-Puyoulet, Panagiotis Sapountzis, Nadia Bendridi, Marjolaine Rey, Yvan Rahbé, Hubert Charles, Federica Calevro and Stefano Colella
    Citation: BMC Genomics 2013 14:235
    Content type: Research article Published on:

  15. Mutations in three functionally diverse genes cause Rett Syndrome. Although the functions of Forkhead box G1 (FOXG1), Methyl CpG binding protein 2 (MECP2) and Cyclin-dependent kinase-like 5 (CDKL5) have been stud...

    Authors: Morana Vitezic, Nicolas Bertin, Robin Andersson, Leonard Lipovich, Hideya Kawaji, Timo Lassmann, Albin Sandelin, Peter Heutink, Dan Goldowitz, Thomas Ha, Peter Zhang, Annarita Patrizi, Michela Fagiolini, Alistair RR Forrest, Piero Carninci and Alka Saxena
    Citation: BMC Genomics 2014 15:1177
    Content type: Research article Published on:

  16. Infestation of ovine skin with the ectoparasitic mite Psoroptes ovis results in a rapid cutaneous immune response, leading to the crusted skin lesions characteristic of sheep scab. Little is known regarding the m...

    Authors: Stewart TG Burgess, David Frew, Francesca Nunn, Craig A Watkins, Tom N McNeilly, Alasdair J Nisbet and John F Huntley
    Citation: BMC Genomics 2010 11:624
    Content type: Research article Published on:

  17. Aberrational epigenetic marks are believed to play a major role in establishing the abnormal features of cancer cells. Rational use and development of drugs aimed at epigenetic processes requires an understand...

    Authors: Sally Yoo and Mark C Bieda
    Citation: BMC Genomics 2014 15:724
    Content type: Research article Published on:

  18. Mikania micrantha is a vine with strong invasion ability, and its strong sexual reproduction ability is not only the main factor of harm, but also a serious obstacle to control. M. micrantha spreads mainly throug...

    Authors: Chen Liang, Ling Liu, Zhixiao Zhang, Sangzi Ze, Ling Pei, Lichen Feng, Mei Ji, Bin Yang and Ning Zhao
    Citation: BMC Genomics 2023 24:14
    Content type: Research Published on:

  19. Pathogenic Rickettsia species belonging to the spotted fever group are arthropod-borne, obligate intracellular bacteria which exhibit preferential tropism for host microvascular endothelium in the mammalian hosts...

    Authors: Hema P. Narra, Abha Sahni, Jessica Alsing, Casey L. C. Schroeder, George Golovko, Anna M. Nia, Yuriy Fofanov, Kamil Khanipov and Sanjeev K. Sahni
    Citation: BMC Genomics 2020 21:665
    Content type: Research article Published on:

  20. The liver plays a central role in the maintenance of homeostasis and health in general. However, there is substantial inter-individual variation in hepatic gene expression, and although numerous genetic factor...

    Authors: Marc Jan Bonder, Silva Kasela, Mart Kals, Riin Tamm, Kaie Lokk, Isabel Barragan, Wim A Buurman, Patrick Deelen, Jan-Willem Greve, Maxim Ivanov, Sander S Rensen, Jana V van Vliet-Ostaptchouk, Marcel G Wolfs, Jingyuan Fu, Marten H Hofker, Cisca Wijmenga…
    Citation: BMC Genomics 2014 15:860
    Content type: Research article Published on:

  21. As an important epigenetic mark, 5-methylcytosine (5mC) methylation is involved in many DNA-dependent biological processes and plays a role during development and differentiation of multicellular organisms. Ho...

    Authors: Yang Zhang, Cong Liu, He Cheng, Shuanghui Tian, Yingying Liu, Shuang Wang, Huaxin Zhang, Muhammad Saqib, Hairong Wei and Zhigang Wei
    Citation: BMC Genomics 2020 21:498
    Content type: Research article Published on:

  22. The paradigm of resistance evolution to chemotherapeutic agents is that a key coding mutation in a specific gene drives resistance to a particular drug. In the case of resistance to the anti-malarial drug chlo...

    Authors: Geoffrey H Siwo, Asako Tan, Katrina A Button-Simons, Upeka Samarakoon, Lisa A Checkley, Richard S Pinapati and Michael T Ferdig
    Citation: BMC Genomics 2015 16:115
    Content type: Research article Published on:

  23. Nutrition has not only an impact on the general wellbeing of an animal but can also affect reproductive processes. In cattle, feeding regimes can influence the age of puberty onset and alter gonadal developmen...

    Authors: Volker Röttgen, Lisa-Maria Tümmler, Dirk Koczan, Alexander Rebl, Björn Kuhla, Jens Vanselow and Anja Baufeld
    Citation: BMC Genomics 2023 24:485
    Content type: Research Published on:

  24. Fusarium fujikuroi is the causal agent of bakanae, the most significant seed-borne disease of rice. Molecular mechanisms regulating defence responses of rice towards this fungus are no...

    Authors: Slavica Matić, Paolo Bagnaresi, Chiara Biselli, Luigi Orru’, Greice Amaral Carneiro, Ilenia Siciliano, Giampiero Valé, Maria Lodovica Gullino and Davide Spadaro
    Citation: BMC Genomics 2016 17:608
    Content type: Research article Published on:

  25. The AP2/ERF transcription factor is widely distributed across the plant kingdom and plays a crucial role in various abiotic stress responses in plants. Tritipyrum, an octoploid resulting from an intergeneric cros...

    Authors: Xiaojuan Liu, Guangyi Zhou, Songshu Chen, Zhenzhen Jia, Suqin Zhang, Mingjian Ren and Fang He
    Citation: BMC Genomics 2023 24:541
    Content type: Research Published on:

  26. Transcriptional enhancers are frequently bound by a set of transcription factors that collaborate to activate lineage-specific gene expression. Recently, it was appreciated that a subset of enhancers comprise ...

    Authors: Steven Witte, Allan Bradley, Anton J. Enright and Stefan A. Muljo
    Citation: BMC Genomics 2015 16:903
    Content type: Research article Published on:

  27. The heat shock response, induced by cytoplasmic proteotoxic stress, is one of the most highly conserved transcriptional responses. This response, driven by the heat shock transcription factor HSF1, restores pr...

    Authors: Jessica Brunquell, Stephanie Morris, Yin Lu, Feng Cheng and Sandy D. Westerheide
    Citation: BMC Genomics 2016 17:559
    Content type: Research article Published on:

  29. Fusarium Head Blight (FHB) caused primarily by Fusarium graminearum (Fg) is one of the major diseases of small-grain cereals including bread wheat. This disease both reduces yields and causes quality losses due t...

    Authors: Jean-Claude Pasquet, Séjir Chaouch, Catherine Macadré, Sandrine Balzergue, Stéphanie Huguet, Marie-Laure Martin-Magniette, Floriant Bellvert, Xavier Deguercy, Vincent Thareau, Dimitri Heintz, Patrick Saindrenan and Marie Dufresne
    Citation: BMC Genomics 2014 15:629
    Content type: Research article Published on:

  30. Lepidoptera is one group of the largest plant-feeding insects and Spodoptera litura (Lepidoptera: Noctuidae) is one of the most serious agricultural pests in Asia countries. An interesting and unique phenomenon f...

    Authors: Yaqing Chen, Jun Ou, Yucheng Liu, Qiong Wu, Liang Wen, Sichun Zheng, Sheng Li, Qili Feng and Lin Liu
    Citation: BMC Genomics 2020 21:171
    Content type: Research article Published on:

  31. Sugar beet (Beta vulgaris sp. vulgaris) crops account for about 30% of world sugar. Sugar yield is compromised by reproductive growth hence crops must remain vegetative until harvest. Prolonged exposure to cold t...

    Authors: Effie S Mutasa-Göttgens, Anagha Joshi, Helen F Holmes, Peter Hedden and Berthold Göttgens
    Citation: BMC Genomics 2012 13:99
    Content type: Research article Published on:

  32. The generation of induced pluripotent stem cells (iPSCs) has underdefined mechanisms. In addition, leukemia inhibitory factor (LIF) activated Janus kinase/signal transducer and activator of transcription 3 (JA...

    Authors: Ling Wang, Zongliang Jiang, Delun Huang, Jingyue Duan, Chang Huang, Shannon Sullivan, Kaneha Vali, Yexuan Yin, Ming Zhang, Jill Wegrzyn, Xiuchun ( Cindy) Tian and Young Tang
    Citation: BMC Genomics 2018 19:183
    Content type: Research article Published on:

  34. Peripheral blood mononuclear cells (PBMCs) are relatively easily obtainable cells in humans. Gene expression profiles of PBMCs have been shown to reflect the pathological and physiological state of a person. R...

    Authors: Mark Bouwens, Lydia A Afman and Michael Müller
    Citation: BMC Genomics 2008 9:262
    Content type: Research article Published on:

  35. High-mobility group B1 (HMGB1) is both a DNA binding nuclear factor modulating transcription and a crucial cytokine that mediates the response to both infectious and noninfectious inflammation such as autoimmu...

    Authors: Meimei Liao, Jiarui Cao, Wen Chen, Mengwei Wang, Zhihui Jin, Jia Ye, Yijun Ren, Yaxun Wei, Yaqiang Xue, Dong Chen, Yi Zhang and Sen Chen
    Citation: BMC Genomics 2024 25:345
    Content type: Research Published on:

  36. Small RNAs (sRNAs) are 20–30 nt regulatory elements which are responsible for plant development regulation and participate in many plant stress responses. Insufficient inorganic phosphate (Pi) concentration tr...

    Authors: Pawel Sega, Katarzyna Kruszka, Dawid Bielewicz, Wojciech Karlowski, Przemyslaw Nuc, Zofia Szweykowska-Kulinska and Andrzej Pacak
    Citation: BMC Genomics 2021 22:165
    Content type: Research article Published on:

  37. The majority of non-coding RNAs (ncRNAs) involved in mRNA metabolism in mammals have been believed to downregulate the corresponding mRNA expression level in a pre- or post-transcriptional manner by forming sh...

    Authors: Masahiro Uesaka, Osamu Nishimura, Yasuhiro Go, Kinichi Nakashima, Kiyokazu Agata and Takuya Imamura
    Citation: BMC Genomics 2014 15:35
    Content type: Research article Published on:

  38. Genetics studies in the porcine immune system have enhanced selection practices for disease resistance phenotypes and increased the efficacy of porcine models in biomedical research; however limited functional...

    Authors: Ryan J. Corbett, Andrea M. Luttman, Juber Herrera-Uribe, Haibo Liu, Nancy E. Raney, Jenna M. Grabowski, Crystal L. Loving, Christopher K. Tuggle and Catherine W. Ernst
    Citation: BMC Genomics 2022 23:575
    Content type: Research Published on:

  39. Sand rice (Agriophyllum squarrosum) is an annual desert plant adapted to mobile sand dunes in arid and semi-arid regions of Central Asia. The sand rice seeds have excellent nutrition value and have been historica...

    Authors: Pengshan Zhao, Salvador Capella-Gutiérrez, Yong Shi, Xin Zhao, Guoxiong Chen, Toni Gabaldón and Xiao-Fei Ma
    Citation: BMC Genomics 2014 15:872
    Content type: Research article Published on:

  40. Cereal cyst nematode Heterodera avenae, an important soil-borne pathogen in wheat, causes numerous annual yield losses worldwide, and use of resistant cultivars is the best strategy for control. However, target g...

    Authors: Ling-An Kong, Du-Qing Wu, Wen-Kun Huang, Huan Peng, Gao-Feng Wang, Jiang-Kuan Cui, Shi-Ming Liu, Zhi-Gang Li, Jun Yang and De-Liang Peng
    Citation: BMC Genomics 2015 16:801
    Content type: Research article Published on:

  41. Development of the human pancreas requires the precise temporal control of gene expression via epigenetic mechanisms and the binding of key transcription factors. We quantified genome-wide patterns of DNA meth...

    Authors: Ailsa MacCalman, Elisa De Franco, Alice Franklin, Christine S. Flaxman, Sarah J. Richardson, Kathryn Murrall, Joe Burrage, Emma M. Walker, Noel G. Morgan, Andrew T. Hattersley, Emma L. Dempster, Eilis Hannon, Aaron R. Jeffries, Nick D. L. Owens and Jonathan Mill
    Citation: BMC Genomics 2024 25:553
    Content type: Research Published on:

  42. The core promoter is the region flanking the transcription start site (TSS) that directs formation of the pre-initiation complex. Core promoters have been studied intensively in mammals and yeast, but not in m...

    Authors: Sourav Roy, Laetitia Poidevin, Tao Jiang and Howard S Judelson
    Citation: BMC Genomics 2013 14:106
    Content type: Research article Published on:

  43. The expression of gene batteries, genomic units of functionally linked genes which are activated by similar sets of cis- and trans-acting regulators, has been proposed as a major determinant of cell specializatio...

    Authors: Sven Nelander, Erik Larsson, Erik Kristiansson, Robert Månsson, Olle Nerman, Mikael Sigvardsson, Petter Mostad and Per Lindahl
    Citation: BMC Genomics 2005 6:68
    Content type: Research article Published on:

  44. The life cycle of human immunodeficiency virus type-1 (HIV-1) makes possible the realization of regulatory strategies that can lead to complex dynamical behavior of the system. We analyze the strategy which is...

    Authors: Vitaly A Likhoshvai, Tamara M Khlebodarova, Sergei I Bazhan, Irina A Gainova, Valery A Chereshnev and Gennady A Bocharov
    Citation: BMC Genomics 2014 15(Suppl 12):S1
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 12

  45. EST (expressed sequence tag) sequences and their annotation provide a highly valuable resource for gene discovery, genome sequence annotation, and other genomics studies that can be applied in genetics, breedi...

    Authors: Ishminder K Mann, Jill L Wegrzyn and Om P Rajora
    Citation: BMC Genomics 2013 14:702
    Content type: Research article Published on:

  47. Adventitious roots (ARs) represent an important organ system for water and nutrient uptake in lotus plants because of degeneration of the principal root. The WUSCHEL-related homeobox (WOX) gene regulates plant de...

    Authors: Liu quan, Liang Shiting, Zhao Chen, Han Yuyan, Zhao Minrong, Li Shuyan and Cheng Libao
    Citation: BMC Genomics 2023 24:719
    Content type: Research Published on:

  48. Rice in tropical and sub-tropical areas is often subjected to cold stress at the seedling stage, resulting in poor growth and yield loss. Although japonica rice is generally more cold tolerant (CT) than indica ri...

    Authors: Fan Zhang, Liyu Huang, Wensheng Wang, Xiuqin Zhao, Linghua Zhu, Binying Fu and Zhikang Li
    Citation: BMC Genomics 2012 13:461
    Content type: Research article Published on:

  49. African animal trypanosomiasis (AAT) caused by tsetse fly-transmitted protozoa of the genus Trypanosoma is a major constraint on livestock and agricultural production in Africa and is among the top ten global cat...

    Authors: Grace M O'Gorman, Stephen DE Park, Emmeline W Hill, Kieran G Meade, Paul M Coussens, Morris Agaba, Jan Naessens, Stephen J Kemp and David E MacHugh
    Citation: BMC Genomics 2009 10:207
    Content type: Research article Published on:

  50. Drought stress is one of the most severe problem limited agricultural productivity worldwide. It has been reported that plants response to drought-stress by sophisticated mechanisms at both transcriptional and...

    Authors: Qiansi Chen, Meng Li, Zhongchun Zhang, Weiwei Tie, Xia Chen, Lifeng Jin, Niu Zhai, Qingxia Zheng, Jianfeng Zhang, Ran Wang, Guoyun Xu, Hui Zhang, Pingping Liu and Huina Zhou
    Citation: BMC Genomics 2017 18:62
    Content type: Research article Published on:

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