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  1. The tall wheatgrass species Thinopyrum elongatum carries a strong fusarium head blight (FHB) resistance locus located on the long arm of chromosome 7 (7EL) as well as resistance to leaf and stem rusts, all diseas...

    Authors: David Konkin, Ya-Chih Hsueh, Morgan Kirzinger, Marie Kubaláková, Aparna Haldar, Margaret Balcerzak, Fangpu Han, George Fedak, Jaroslav Doležel, Andrew Sharpe and Thérèse Ouellet
    Citation: BMC Genomics 2022 23:228
    Content type: Research Published on:

  2. The ability of animals and their microbiomes to adapt to starvation and then restore homeostasis after refeeding is fundamental to their continued survival and symbiosis. The intestine is the primary site of n...

    Authors: Jayanth Jawahar, Alexander W. McCumber, Colin R. Lickwar, Caroline R. Amoroso, Sol Gomez de la Torre Canny, Sandi Wong, Margaret Morash, James H. Thierer, Steven A. Farber, Brendan J. M. Bohannan, Karen Guillemin and John F. Rawls
    Citation: BMC Genomics 2022 23:225
    Content type: Research Published on:

  3. Understanding how evolutionary forces relating to climate have shaped the patterns of genetic variation within and between species is a fundamental pursuit in biology. Iranian indigenous chickens have evolved ...

    Authors: Hojjat Asadollahpour Nanaei, Hamed Kharrati-Koopaee and Ali Esmailizadeh
    Citation: BMC Genomics 2022 23:224
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2022 23:395

  5. Mastitis is a very common disease in the dairy industry that producers encounter daily. Transcriptomics, using RNA-Sequencing (RNA - Seq) technology, can be used to study the functional aspect of mastitis resi...

    Authors: V. Asselstine, J. F. Medrano and A. Cánovas
    Citation: BMC Genomics 2022 23:222
    Content type: Research Published on:

  6. Environmental exposures in utero which modify DNA methylation may have a long-lasting impact on health and disease in offspring. We aimed to identify and replicate previously published genomic loci where DNA meth...

    Authors: Loubna Akhabir, Randa Stringer, Dipika Desai, Piush J Mandhane, Meghan B Azad, Theo J Moraes, Padmaja Subbarao, Stuart E Turvey, Guillaume Paré and Sonia S. Anand
    Citation: BMC Genomics 2022 23:221
    Content type: Research article Published on:

  8. Adipose tissue is an important endocrine and energy-storage organ in organisms, and it plays a crucial role in the energy-metabolism balance. Previous studies have found that sex-linked dwarf (SLD) chickens ge...

    Authors: Minmin Yang, Bowen Hu, Donglei Sun, Changbin Zhao, Haohui Wei, Dajian Li, Zhiying Liao, Yongxia Zhao, Jinping Liang, Meiqing Shi, Qingbin Luo, Qinghua Nie, Xiquan Zhang, Dexiang Zhang and Hongmei Li
    Citation: BMC Genomics 2022 23:219
    Content type: Research article Published on:

  9. Colocasia gigantea, Caladium bicolor and Xanthosoma sagittifolium are three worldwide famous ornamental and/or vegetable plants in the Araceae family, these species in the subfamily Aroideae are phylogenetically...

    Authors: Bicong Li, Tao Liu, Asjad Ali, Yao Xiao, Nan Shan, Jingyu Sun, Yingjin Huang, Qinghong Zhou and Qianglong Zhu
    Citation: BMC Genomics 2022 23:218
    Content type: Research Published on:

  10. Salmonella spp. is a major foodborne pathogen with a wide variety of serovars associated with human cases and food sources. Nevertheless, in Europe a panel of ten serovars is responsible for up to 80% of confirme...

    Authors: Emeline Cherchame, Laurent Guillier, Renaud Lailler, Marie-Leone Vignaud, Nathalie Jourdan-Da Silva, Simon Le Hello, François-Xavier Weill and Sabrina Cadel-Six
    Citation: BMC Genomics 2022 23:217
    Content type: Research Published on:

  12. Copy number variation (CNV) has been routinely studied using bulk-cell sequencing. However, CNV is not well studied on the single-cell level except for humans and a few model organisms.

    Authors: Liu Yang, Yahui Gao, Adam Oswalt, Lingzhao Fang, Clarissa Boschiero, Mahesh Neupane, Charles G. Sattler, Cong-jun Li, Eyal Seroussi, Lingyang Xu, Lv Yang, Li Li, Hongping Zhang, Benjamin D. Rosen, Curtis P. Van Tassell, Yang Zhou…
    Citation: BMC Genomics 2022 23:215
    Content type: Research Published on:

  13. The “Assay for Transposase Accessible Chromatin sequencing” (ATAC-seq) is an efficient and easy to implement protocol to measure chromatin accessibility that has been widely used in multiple applications study...

    Authors: Hao Zhang, Michael E. Rice, Joseph W. Alvin, Dominique Farrera-Gaffney, James J. Galligan, Michael D. L. Johnson and Darren A. Cusanovich
    Citation: BMC Genomics 2022 23:214
    Content type: Research Published on:

  14. Recent evidences have suggested that human microorganisms participate in important biological activities in the human body. The dysfunction of host-microbiota interactions could lead to complex human disorders...

    Authors: Yu-An Huang, Zhi-An Huang, Jian-Qiang Li, Zhu-Hong You, Lei Wang, Hai-Cheng Yi and Chang-Qing Yu
    Citation: BMC Genomics 2022 22(Suppl 1):916
    Content type: Research Published on:

    This article is part of a Supplement: Volume 22 Supplement 1

  15. Respectively, prostate cancer (PCa) and breast cancer (BC) are the second most and most commonly diagnosed cancer in men and women, and they account for a majority of cancer-related deaths world-wide. Cancer c...

    Authors: Yindan Lin, Ze Yang, Jingjia Li, Yandi Sun, Xueyun Zhang, Zihao Qu, Yan Luo and Lihong Zhang
    Citation: BMC Genomics 2022 23:213
    Content type: Research Published on:

  16. PRDM9 is a key regulator of meiotic recombination in most metazoans, responsible for reshuffling parental genomes. During meiosis, the PRDM9 protein recognizes and binds specific target motifs via its array of C2

    Authors: Elena Damm, Kristian K. Ullrich, William B. Amos and Linda Odenthal-Hesse
    Citation: BMC Genomics 2022 23:212
    Content type: Research Published on:

  18. Streptococcus thermophilus is a Gram-positive bacterium widely used as starter in the dairy industry as well as in many traditional fermented products. In addition to its technological importance, it has also gai...

    Authors: Emeline Roux, Aurélie Nicolas, Florence Valence, Grégoire Siekaniec, Victoria Chuat, Jacques Nicolas, Yves Le Loir and Eric Guédon
    Citation: BMC Genomics 2022 23:210
    Content type: Research Published on:

  19. A decline in the level of genetic diversity in livestock can result in reduced response to selection, greater incidence of genetic defects, and inbreeding depression. In this context, various metrics have been...

    Authors: Henrique Alberto Mulim, Luiz F. Brito, Luís Fernando Batista Pinto, José Bento Sterman Ferraz, Lais Grigoletto, Marcio Ribeiro Silva and Victor Breno Pedrosa
    Citation: BMC Genomics 2022 23:209
    Content type: Research Published on:

  20. Frequent occurrence of extreme high temperature is a major threat to crop production. Increasing evidence demonstrates that long non-coding RNAs (lncRNAs) have important biological functions in the regulation ...

    Authors: Xiaolin Hu, Qiye Wei, Hongying Wu, Yuanxiang Huang, Xiaojian Peng, Guomin Han, Qing Ma and Yang Zhao
    Citation: BMC Genomics 2022 23:208
    Content type: Research Published on:

  22. Cryptocaryonosis caused by Cryptocaryon irritans is one of the major diseases of large yellow croaker (Larimichthys crocea), which lead to massive economic losses annually to the aquaculture industry of L. crocea

    Authors: Yulin Bai, Mei Wang, Ji Zhao, Huaqiang Bai, Xinyi Zhang, Jiaying Wang, Qiaozhen Ke, Ang Qu, Fei Pu, Weiqiang Zheng, Tao Zhou and Peng Xu
    Citation: BMC Genomics 2022 23:206
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2022 23:370

  23. Chilling injury of mung bean (Vigna radiata (L.)) during the blooming and podding stages is a major agricultural threat in Northeast China. Uniconazole (UNZ) can alleviate water deficit stress in soybean and wate...

    Authors: Hanqiao Hu, Naijie Feng, Xuefeng Shen, Liming Zhao and Dianfeng Zheng
    Citation: BMC Genomics 2022 23:205
    Content type: Research Published on:

  25. Ilex (Aquifoliaceae) are of great horticultural importance throughout the world for their foliage and decorative berries, yet a dearth of genetic information has hampered our understanding of phylogenetic relati...

    Authors: Kewang Xu, Chenxue Lin, Shiou Yih Lee, Lingfeng Mao and Kaikai Meng
    Citation: BMC Genomics 2022 23:203
    Content type: Research Published on:

  26. Shotgun sequencing of cultured microbial isolates/individual eukaryotes (whole-genome sequencing) and microbial communities (metagenomics) has become commonplace in biology. Very often, sequenced samples encom...

    Authors: Arkadiy I. Garber, Catherine R. Armbruster, Stella E. Lee, Vaughn S. Cooper, Jennifer M. Bomberger and Sean M. McAllister
    Citation: BMC Genomics 2022 23:202
    Content type: Software Published on:

  27. Apoptosis plays important roles in a variety of functions, including immunity and response to environmental stress. The Inhibitor of Apoptosis (IAP) gene family of apoptosis regulators is expanded in molluscs,...

    Authors: Erin M. Witkop, Dina A. Proestou and Marta Gomez-Chiarri
    Citation: BMC Genomics 2022 23:201
    Content type: Research Published on:

  28. Genomic prediction (GP) based on single nucleotide polymorphisms (SNP) has become a broadly used tool to increase the gain of selection in plant breeding. However, using predictors that are biologically closer...

    Authors: Po-Ya Wu, Benjamin Stich, Marius Weisweiler, Asis Shrestha, Alexander Erban, Philipp Westhoff and Delphine Van Inghelandt
    Citation: BMC Genomics 2022 23:200
    Content type: Research Published on:

  29. RAD51 proteins, which are conserved in all eukaryotes, repair DNA double-strand breaks. This is critical to homologous chromosome pairing and recombination enabling successful reproduction. Work in Arabidopsis...

    Authors: Claire Milsted, Bo Dai, Nelson Garcia, Lu Yin, Yan He, Shahryar Kianian, Wojciech Pawlowski and Changbin Chen
    Citation: BMC Genomics 2022 23:199
    Content type: Research Published on:

  30. Sphaerophoria rueppellii, a European species of hoverfly, is a highly effective beneficial predator of hemipteran crop pests including aphids, thrips and coleopteran/lepidopteran larvae in integrated pest managem...

    Authors: Emma Bailey, Linda Field, Christopher Rawlings, Rob King, Fady Mohareb, Keywan-Hassani Pak, David Hughes, Martin Williamson, Eric Ganko, Benjamin Buer and Ralf Nauen
    Citation: BMC Genomics 2022 23:198
    Content type: Research Published on:

  31. Chemogenomic profiling is a powerful approach for understanding the genome-wide cellular response to small molecules. First developed in Saccharomyces cerevisiae, chemogenomic screens provide direct, unbiased ide...

    Authors: Marjan Barazandeh, Divya Kriti, Corey Nislow and Guri Giaever
    Citation: BMC Genomics 2022 23:197
    Content type: Research Published on:

  32. Expression quantitative trait loci (eQTLs) analyses have been widely used to identify genetic variants associated with gene expression levels to understand what molecular mechanisms underlie genetic traits. Th...

    Authors: Jian-Rong Li, Mabel Tang, Yafang Li, Christopher I. Amos and Chao Cheng
    Citation: BMC Genomics 2022 23:196
    Content type: Research Published on:

  33. The investigation of molecular mechanisms involved in polysaccharides and saponin metabolism is critical for genetic engineering of Polygonatum cyrtonema Hua to raise major active ingredient content. Up to now, t...

    Authors: Dandan Li, Qing Wang, Songshu Chen, Hongchang Liu, Keqin Pan, Jinling Li, Chunli Luo and Hualei Wang
    Citation: BMC Genomics 2022 23:195
    Content type: Research Published on:

  34. One of the most promising strategies of Pine Pitch Canker (PPC) management is the use of reproductive plant material resistant to the disease. Understanding the complexity of plant transcriptome that underlies...

    Authors: Cristina Zamora-Ballesteros, Jorge Martín-García, Aroa Suárez-Vega and Julio Javier Diez
    Citation: BMC Genomics 2022 23:194
    Content type: Research Published on:

  35. Structural variants (SV) are causative for some prominent phenotypic traits of livestock as different comb types in chickens or color patterns in pigs. Their effects on production traits are also increasingly ...

    Authors: Johannes Geibel, Nora Paulina Praefke, Steffen Weigend, Henner Simianer and Christian Reimer
    Citation: BMC Genomics 2022 23:193
    Content type: Research Published on:

  36. The hard clam Mercenaria mercenaria is a major marine resource along the Atlantic coasts of North America and has been introduced to other continents for resource restoration or aquaculture activities. Significan...

    Authors: Sarah Farhat, Eric Bonnivard, Emmanuelle Pales Espinosa, Arnaud Tanguy, Isabelle Boutet, Nadège Guiglielmoni, Jean-François Flot and Bassem Allam
    Citation: BMC Genomics 2022 23:192
    Content type: Research article Published on:

  37. Tibetan cashmere goats are served as a valuable model for high altitude adaptation and hypoxia complications related studies, while the cashmere produced by these goats is an important source of income for the...

    Authors: Bingru Zhao, Cuiling Wu, Abdul Sammad, Zhen Ma, Langda Suo, Yujiang Wu and Xuefeng Fu
    Citation: BMC Genomics 2022 23:191
    Content type: Research Published on:

  38. Walnuts (Juglans regia L.) are known for their nutrient-rich nuts and are one of the important economic tree species in the world. However, due to global warming and soil salinization, walnuts suffer from various...

    Authors: Xuejiao Liu, Feiyan Yu, Guiyan Yang, Xiaoqiang Liu and Shaobing Peng
    Citation: BMC Genomics 2022 23:190
    Content type: Research Published on:

  39. Subclinical mastitis, the inflammation of the mammary gland lacking clinical symptoms, is one of the most prevalent and costly diseases in dairy farming worldwide. Milk microRNAs (miRNAs) encapsulated in extra...

    Authors: Mara D. Saenz-de-Juano, Giulia Silvestrelli, Stefan Bauersachs and Susanne E. Ulbrich
    Citation: BMC Genomics 2022 23:189
    Content type: Research Published on:

  40. The repulsive guidance molecule a (RGMa) is a GPI-anchor axon guidance molecule first found to play important roles during neuronal development. RGMa expression patterns and signaling pathways via Neogenin and...

    Authors: Aline Gonçalves Lio Copola, Íria Gabriela Dias dos Santos, Luiz Lehmann Coutinho, Luiz Eduardo Vieira Del-Bem, Paulo Henrique de Almeida Campos-Junior, Izabela Mamede Costa Andrade da Conceição, Júlia Meireles Nogueira, Alinne do Carmo Costa, Gerluza Aparecida Borges Silva and Erika Cristina Jorge
    Citation: BMC Genomics 2022 23:188
    Content type: Research Published on:

  41. A variety of protocols exist for producing whole genome run-on transcription datasets. However, little is known about how differences between these protocols affect the signal within the resulting libraries.

    Authors: Samuel Hunter, Rutendo F. Sigauke, Jacob T. Stanley, Mary A. Allen and Robin D. Dowell
    Citation: BMC Genomics 2022 23:187
    Content type: Research Published on:

  42. MicroRNAs (miRNAs) are a family of short non-coding RNA molecules and play important roles in various biological processes. However, knowledge of the expression profiles and function of miRNAs on the regulatio...

    Authors: Xin Liu, Yuehua Zhu, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Jiaxue Cao, Li Li, Hongping Zhang and Linjie Wang
    Citation: BMC Genomics 2022 23:186
    Content type: Research Published on:

  43. Citrus is one of the most important fresh fruit crops worldwide. Juice sac granulation is a physiological disorder, which leads to a reduction in soluble solid concentration, total sugar, and titratable acidit...

    Authors: Zixuan Li, Liming Wu, Ce Wang, Yue Wang, Ligang He, Zhijing Wang, Xiaofang Ma, Fuxi Bai, Guizhi Feng, Jihong Liu, Yingchun Jiang and Fang Song
    Citation: BMC Genomics 2022 23:185
    Content type: Research Published on:

  44. Maize is one of the most important food crops worldwide. Roots play important role in maize productivity through water and nutrient uptake from the soil. Improving maize root traits for efficient water uptake ...

    Authors: Junqiao Song, Daowen Lu, Yongfeng Niu, Haichao Sun, Pan Zhang, Wenheng Dong, Yongjiang Li, Yingying Zhang, Lianyong Lu, Qi Men, Xiaohui Zhang, Pengxun Ren and Chuankui Chen
    Citation: BMC Genomics 2022 23:184
    Content type: Research Published on:

  47. Meiotic recombination is one of the important phenomena contributing to gamete genome diversity. However, except for human and a few model organisms, it is not well studied in livestock, including cattle.

    Authors: Liu Yang, Yahui Gao, Mingxun Li, Ki-Eun Park, Shuli Liu, Xiaolong Kang, Mei Liu, Adam Oswalt, Lingzhao Fang, Bhanu P. Telugu, Charles G. Sattler, Cong-jun Li, John B. Cole, Eyal Seroussi, Lingyang Xu, Lv Yang…
    Citation: BMC Genomics 2022 23:181
    Content type: Research Published on:

  48. The cyclical nature of gene expression in the intraerythrocytic development cycle (IDC) of the malaria parasite, Plasmodium falciparum, confounds the accurate detection of specific transcriptional differences, e....

    Authors: Gabriel J. Foster, Mackenzie A. C. Sievert, Katrina Button-Simons, Katelyn M. Vendrely, Jeanne Romero-Severson and Michael T. Ferdig
    Citation: BMC Genomics 2022 23:180
    Content type: Methodology article Published on:

  49. The TIFY gene family is a group of plant-specific transcription factors involved in regulation of plant growth and development and a variety of stress responses. However, the TIFY family has not yet been well cha...

    Authors: Junjie Tao, Huimin Jia, Mengting Wu, Wenqi Zhong, Dongfeng Jia, Zupeng Wang and Chunhui Huang
    Citation: BMC Genomics 2022 23:179
    Content type: Research Published on:

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BMC Genomics

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