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  1. Mutans streptococci are a group of gram-positive bacteria including the primary cariogenic dental pathogen Streptococcus mutans and closely related species. Two component systems (TCSs) composed of a signal sensi...

    Authors: Lifu Song, Padhmanand Sudhakar, Wei Wang, Georg Conrads, Anke Brock, Jibin Sun, Irene Wagner-Döbler and An-Ping Zeng
    Citation: BMC Genomics 2012 13:128
  2. Light represents an important environmental cue, which exerts considerable influence on the metabolism of fungi. Studies with the biotechnological fungal workhorse Trichoderma reesei (Hypocrea jecorina) have reve...

    Authors: Monika Schmoll, Chaoguang Tian, Jianping Sun, Doris Tisch and N Louise Glass
    Citation: BMC Genomics 2012 13:127
  3. Picrorhiza kurrooa Royle ex Benth. is an endangered plant species of medicinal importance. The medicinal property is attributed to monoterpenoids picroside I and II, which are modulated by temperature. The transc...

    Authors: Parul Gahlan, Heikham Russiachand Singh, Ravi Shankar, Niharika Sharma, Anita Kumari, Vandna Chawla, Paramvir Singh Ahuja and Sanjay Kumar
    Citation: BMC Genomics 2012 13:126
  4. The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species. Despite comprising up to 5% of the genome, little is known about the...

    Authors: Jennifer Lawton, Thibaut Brugat, Yam Xue Yan, Adam James Reid, Ulrike Böhme, Thomas Dan Otto, Arnab Pain, Andrew Jackson, Matthew Berriman, Deirdre Cunningham, Peter Preiser and Jean Langhorne
    Citation: BMC Genomics 2012 13:125
  5. The degree of conservation of gene expression between homologous organs largely remains an open question. Several recent studies reported some evidence in favor of such conservation. Most studies compute organ...

    Authors: Barbara Piasecka, Zoltán Kutalik, Julien Roux, Sven Bergmann and Marc Robinson-Rechavi
    Citation: BMC Genomics 2012 13:124
  6. MicroRNA (miRNA) is a class of functional non-coding small RNA with 19-25 nucleotides in length while Amur grape (Vitis amurensis Rupr.) is an important wild fruit crop with the strongest cold resistance among th...

    Authors: Chen Wang, Jian Han, Chonghuai Liu, Korir Nicholas Kibet, Emrul Kayesh, Lingfei Shangguan, Xiaoying Li and Jinggui Fang
    Citation: BMC Genomics 2012 13:122
  7. Bovine leukemia virus (BLV) is associated with enzootic bovine leukosis and is closely related to human T-cell leukemia virus type I. The Tax protein of BLV is a transcriptional activator of viral replication ...

    Authors: Mariluz Arainga, Eri Takeda and Yoko Aida
    Citation: BMC Genomics 2012 13:121
  8. The sequence of the pathogen Mycobacterium tuberculosis (Mtb) strain H37Rv has been available for over a decade, but the biology of the pathogen remains poorly understood. Genome sequences from other Mtb strains ...

    Authors: Abigail Manson McGuire, Brian Weiner, Sang Tae Park, Ilan Wapinski, Sahadevan Raman, Gregory Dolganov, Matthew Peterson, Robert Riley, Jeremy Zucker, Thomas Abeel, Jared White, Peter Sisk, Christian Stolte, Mike Koehrsen, Robert T Yamamoto, Milena Iacobelli-Martinez…
    Citation: BMC Genomics 2012 13:120
  9. In the silkworm, Bombyx mori, femaleness is strongly controlled by the female-specific W chromosome. Originally, it was presumed that the W chromosome encodes female-determining gene(s), accordingly called Fem. H...

    Authors: Kahori Hara, Tsuguru Fujii, Yutaka Suzuki, Sumio Sugano, Toru Shimada, Susumu Katsuma and Shinpei Kawaoka
    Citation: BMC Genomics 2012 13:119
  10. A valuable tool for both research and industry, in vitro fertilization (IVF) has applications range from gamete selection and preservation of traits to cloning. Although IVF has achieved worldwide use, with ap...

    Authors: Ashley M Driver, Francisco Peñagaricano, Wen Huang, Khawaja R Ahmad, Katie S Hackbart, Milo C Wiltbank and Hasan Khatib
    Citation: BMC Genomics 2012 13:118
  11. Expression traits can vary quantitatively between individuals and have a complex inheritance. Identification of the genetics underlying transcript variation can help in the understanding of phenotypic variatio...

    Authors: Francisco A Cubillos, Jennifer Yansouni, Hamid Khalili, Sandrine Balzergue, Samira Elftieh, Marie-Laure Martin-Magniette, Yann Serrand, Loïc Lepiniec, Sébastien Baud, Bertrand Dubreucq, Jean-Pierre Renou, Christine Camilleri and Olivier Loudet
    Citation: BMC Genomics 2012 13:117
  12. In addition to genome sequencing, accurate functional annotation of genomes is required in order to carry out comparative and evolutionary analyses between species. Among primates, the human genome is the most...

    Authors: Michael Dannemann, Birgit Nickel, Esther Lizano, Hernán A Burbano and Janet Kelso
    Citation: BMC Genomics 2012 13:116
  13. The placenta is a key component in understanding the physiological processes involved in pregnancy. Characterizing genes critical for placental function can serve as a basis for identifying mechanisms underlyi...

    Authors: Jinsil Kim, Keyan Zhao, Peng Jiang, Zhi-xiang Lu, Jinkai Wang, Jeffrey C Murray and Yi Xing
    Citation: BMC Genomics 2012 13:115
  14. This study describes how the complete mitogenome of a terrestrial snail, Cylindrus obtusus (Draparnaud, 1805) was sequenced without PCRs from a collection specimen that had been in 70% ethanol for 8 years. The mi...

    Authors: Dick SJ Groenenberg, Walter Pirovano, Edmund Gittenberger and Menno Schilthuizen
    Citation: BMC Genomics 2012 13:114
  15. Knowledge of germplasm diversity and relationships among elite breeding materials is fundamentally important in crop improvement. We genotyped 450 maize inbred lines developed and/or widely used by CIMMYT bree...

    Authors: Kassa Semagn, Cosmos Magorokosho, Bindiganavile S Vivek, Dan Makumbi, Yoseph Beyene, Stephen Mugo, BM Prasanna and Marilyn L Warburton
    Citation: BMC Genomics 2012 13:113
  16. Actinoplanes sp. SE50/110 is known as the wild type producer of the alpha-glucosidase inhibitor acarbose, a potent drug used worldwide in the treatment of type-2 diabetes mellitus. As the incidence of diabetes is...

    Authors: Patrick Schwientek, Rafael Szczepanowski, Christian Rückert, Jörn Kalinowski, Andreas Klein, Klaus Selber, Udo F Wehmeier, Jens Stoye and Alfred Pühler
    Citation: BMC Genomics 2012 13:112
  17. Different Cupriavidus metallidurans strains isolated from metal-contaminated and other anthropogenic environments were genotypically and phenotypically compared with C. metallidurans type strain CH34. The latter ...

    Authors: Rob Van Houdt, Pieter Monsieurs, Kristel Mijnendonckx, Ann Provoost, Ann Janssen, Max Mergeay and Natalie Leys
    Citation: BMC Genomics 2012 13:111
  18. Dickeya dadantii and Pectobacterium atrosepticum are phytopathogenic enterobacteria capable of facultative anaerobic growth in a wide range of O2 concentrations found in plant and natural environments. The transc...

    Authors: Lavanya Babujee, Jennifer Apodaca, Venkatesh Balakrishnan, Paul Liss, Patricia J Kiley, Amy O Charkowski, Jeremy D Glasner and Nicole T Perna
    Citation: BMC Genomics 2012 13:110
  19. Drosophila albomicans is a unique model organism for studying both sex chromosome and B chromosome evolution. A pair of its autosomes comprising roughly 40% of the whole genome has fused to the ancient X and Y ch...

    Authors: Qi Zhou, Hong-mei Zhu, Quan-fei Huang, Li Zhao, Guo-jie Zhang, Scott W Roy, Beatriz Vicoso, Zhao-lin Xuan, Jue Ruan, Yue Zhang, Ruo-ping Zhao, Chen Ye, Xiu-qing Zhang, Jun Wang, Wen Wang and Doris Bachtrog
    Citation: BMC Genomics 2012 13:109
  20. Drug resistance in the malaria parasite Plasmodium falciparum severely compromises the treatment and control of malaria. A knowledge of the critical mutations conferring resistance to particular drugs is importan...

    Authors: Katarzyna Kinga Modrzynska, Alison Creasey, Laurence Loewe, Timothee Cezard, Sofia Trindade Borges, Axel Martinelli, Louise Rodrigues, Pedro Cravo, Mark Blaxter, Richard Carter and Paul Hunt
    Citation: BMC Genomics 2012 13:106
  21. Biological systems respond to changes in both the Earth's magnetic and gravitational fields, but as experiments in space are expensive and infrequent, Earth-based simulation techniques are required. A high gra...

    Authors: Ana I Manzano, Jack JWA van Loon, Peter CM Christianen, Juana M Gonzalez-Rubio, F Javier Medina and Raul Herranz
    Citation: BMC Genomics 2012 13:105
  22. Field pea (Pisum sativum L.) and faba bean (Vicia faba L.) are cool-season grain legume species that provide rich sources of food for humans and fodder for livestock. To date, both species have been relative 'gen...

    Authors: Sukhjiwan Kaur, Luke W Pembleton, Noel OI Cogan, Keith W Savin, Tony Leonforte, Jeffrey Paull, Michael Materne and John W Forster
    Citation: BMC Genomics 2012 13:104
  23. Coffee trees (Rubiaceae) and tomato (Solanaceae) belong to the Asterid clade, while grapevine (Vitaceae) belongs to the Rosid clade. Coffee and tomato separated from grapevine 125 million years ago, while coff...

    Authors: Romain Guyot, Florent Lefebvre-Pautigny, Christine Tranchant-Dubreuil, Michel Rigoreau, Perla Hamon, Thierry Leroy, Serge Hamon, Valérie Poncet, Dominique Crouzillat and Alexandre de Kochko
    Citation: BMC Genomics 2012 13:103
  24. Clostridium beijerinckii is a prominent solvent-producing microbe that has great potential for biofuel and chemical industries. Although transcriptional analysis is essential to understand gene functions and regu...

    Authors: Yi Wang, Xiangzhen Li, Yuejian Mao and Hans P Blaschek
    Citation: BMC Genomics 2012 13:102
  25. Plants react to iron deficiency stress adopting different kind of adaptive responses. Tomato, a Strategy I plant, improves iron uptake through acidification of rhizosphere, reduction of Fe3+ to Fe2+ and transport...

    Authors: Anita Zamboni, Laura Zanin, Nicola Tomasi, Mario Pezzotti, Roberto Pinton, Zeno Varanini and Stefano Cesco
    Citation: BMC Genomics 2012 13:101
  26. Sugar beet (Beta vulgaris sp. vulgaris) crops account for about 30% of world sugar. Sugar yield is compromised by reproductive growth hence crops must remain vegetative until harvest. Prolonged exposure to cold t...

    Authors: Effie S Mutasa-Göttgens, Anagha Joshi, Helen F Holmes, Peter Hedden and Berthold Göttgens
    Citation: BMC Genomics 2012 13:99
  27. Marmosets are playing an increasingly large and important role in biomedical research. They share genetic, anatomical, and physiological similarities with humans and other primate model species, but their smal...

    Authors: Carolyn G Sweeney, Elizabeth Curran, Susan V Westmoreland, Keith G Mansfield and Eric J Vallender
    Citation: BMC Genomics 2012 13:98
  28. In Drosophila melanogaster, the dosage-compensation system that equalizes X-linked gene expression between males and females, thereby assuring that an appropriate balance is maintained between the expression of g...

    Authors: Philge Philip, Fredrik Pettersson and Per Stenberg
    Citation: BMC Genomics 2012 13:97
  29. Common carp (Cyprinus carpio) is thought to have undergone one extra round of genome duplication compared to zebrafish. Transcriptome analysis has been used to study the existence and timing of genome duplication...

    Authors: Jin-Tu Wang, Jiong-Tang Li, Xiao-Feng Zhang and Xiao-Wen Sun
    Citation: BMC Genomics 2012 13:96
  30. High-density linkage maps facilitate the mapping of target genes and the construction of partial linkage maps around target loci to develop markers for marker-assisted selection (MAS). MAS is quite challenging...

    Authors: Yoshinari Moriguchi, Tokuko Ujino-Ihara, Kentaro Uchiyama, Norihiro Futamura, Maki Saito, Saneyoshi Ueno, Asako Matsumoto, Naoki Tani, Hideaki Taira, Kenji Shinohara and Yoshihiko Tsumura
    Citation: BMC Genomics 2012 13:95
  31. Genome-wide gene expression profiling and detailed physiological investigation were used for understanding the molecular mechanism and physiological response of Gossypium herbaceum, which governs the adaptability...

    Authors: Alok Ranjan, Deepti Nigam, Mehar H Asif, Ruchi Singh, Sanjay Ranjan, Shrikant Mantri, Neha Pandey, Ila Trivedi, Krishan Mohan Rai, Satya N Jena, Bhupendra Koul, Rakesh Tuli, Uday V Pathre and Samir V Sawant
    Citation: BMC Genomics 2012 13:94
  32. In rodent models and in humans the impact of gestational diets on the offspring's phenotype was shown experimentally and epidemiologically. Adverse environmental conditions during fetal development provoke an ...

    Authors: Michael Oster, Eduard Murani, Cornelia C Metges, Siriluck Ponsuksili and Klaus Wimmers
    Citation: BMC Genomics 2012 13:93
  33. Transcriptome analysis is increasingly being used to study the evolutionary origins and ecology of non-model plants. One issue for both transcriptome assembly and differential gene expression analyses is the c...

    Authors: Nicole Gruenheit, Oliver Deusch, Christian Esser, Matthias Becker, Claudia Voelckel and Peter Lockhart
    Citation: BMC Genomics 2012 13:92
  34. A central goal in Huntington's disease (HD) research is to identify and prioritize candidate targets for neuroprotective intervention, which requires genome-scale information on the modifiers of early-stage ne...

    Authors: François-Xavier Lejeune, Lilia Mesrob, Frédéric Parmentier, Cedric Bicep, Rafael P Vazquez-Manrique, J Alex Parker, Jean-Philippe Vert, Cendrine Tourette and Christian Neri
    Citation: BMC Genomics 2012 13:91
  35. The peanut (Arachis hypogaea L.) is an important oilseed crop in tropical and subtropical regions of the world. However, little about the molecular biology of the peanut is currently known. Recently, next-generat...

    Authors: Jianan Zhang, Shan Liang, Jialei Duan, Jin Wang, Silong Chen, Zengshu Cheng, Qiang Zhang, Xuanqiang Liang and Yurong Li
    Citation: BMC Genomics 2012 13:90
  36. The genome of Mycobacterium avium subspecies paratuberculosis (MAP) is remarkably homogeneous among the genomes of bovine, human and wildlife isolates. However, previous work in our laboratories with the bovine K...

    Authors: John P Bannantine, Chia-wei Wu, Chungyi Hsu, Shiguo Zhou, David C Schwartz, Darrell O Bayles, Michael L Paustian, David P Alt, Srinand Sreevatsan, Vivek Kapur and Adel M Talaat
    Citation: BMC Genomics 2012 13:89
  37. Technological advances in high throughput genome sequencing are making whole genome sequencing (WGS) available as a routine tool for bacterial typing. Standardized procedures for identification of relevant gen...

    Authors: Pimlapas Leekitcharoenphon, Oksana Lukjancenko, Carsten Friis, Frank M Aarestrup and David W Ussery
    Citation: BMC Genomics 2012 13:88
  38. The Tasmanian devil (Sarcophilus harrisii) is currently under threat of extinction due to an unusual fatal contagious cancer called Devil Facial Tumour Disease (DFTD). DFTD is caused by a clonal tumour cell line ...

    Authors: Yuanyuan Cheng, Andrew Stuart, Katrina Morris, Robyn Taylor, Hannah Siddle, Janine Deakin, Menna Jones, Chris T Amemiya and Katherine Belov
    Citation: BMC Genomics 2012 13:87
  39. Small intestine and liver greatly contribute to whole body lipid, cholesterol and phospholipid metabolism but to which extent cholesterol and phospholipid handling in these tissues is affected by high fat West...

    Authors: Charles Desmarchelier, Christoph Dahlhoff, Sylvia Keller, Manuela Sailer, Gerhard Jahreis and Hannelore Daniel
    Citation: BMC Genomics 2012 13:84
  40. MicroRNAs (miRNAs) are endogenously encoded small RNAs that post-transcriptionally regulate gene expression. MiRNAs play essential roles in almost all plant biological processes. Currently, few miRNAs have bee...

    Authors: Pablo Peláez, Minerva S Trejo, Luis P Iñiguez, Georgina Estrada-Navarrete, Alejandra A Covarrubias, José L Reyes and Federico Sanchez
    Citation: BMC Genomics 2012 13:83
  41. The small airway epithelium (SAE), the cell population that covers the human airway surface from the 6th generation of airway branching to the alveoli, is the major site of lung disease caused by smoking. The foc...

    Authors: Neil R Hackett, Marcus W Butler, Renat Shaykhiev, Jacqueline Salit, Larsson Omberg, Juan L Rodriguez-Flores, Jason G Mezey, Yael Strulovici-Barel, Guoqing Wang, Lukas Didon and Ronald G Crystal
    Citation: BMC Genomics 2012 13:82
  42. There has been an increasing body of epidemiologic and biochemical evidence implying the role of cerebral insulin resistance in Alzheimer-type dementia. For a better understanding of the insulin effect on the ...

    Authors: Omar Abdul-Rahman, Maria Sasvari-Szekely, Agota Ver, Klara Rosta, Bernadett K Szasz, Eva Kereszturi and Gergely Keszler
    Citation: BMC Genomics 2012 13:81
  43. Cucurbita pepo is a member of the Cucurbitaceae family, the second- most important horticultural family in terms of economic importance after Solanaceae. The "summer squash" types, including Zucchini and Scallop,...

    Authors: Cristina Esteras, Pedro Gómez, Antonio J Monforte, José Blanca, Nelly Vicente-Dólera, Cristina Roig, Fernando Nuez and Belén Picó
    Citation: BMC Genomics 2012 13:80
  44. The importance of peptide microarrays as a tool for serological diagnostics has strongly increased over the last decade. However, interpretation of the binding signals is still hampered by our limited understa...

    Authors: Victor Greiff, Henning Redestig, Juliane Lück, Nicole Bruni, Atijeh Valai, Susanne Hartmann, Sebastian Rausch, Johannes Schuchhardt and Michal Or-Guil
    Citation: BMC Genomics 2012 13:79

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