Hardy MH: The secret life of the hair follicle. Trends Genet. 1992, 8 (2): 55-61. 10.1016/0168-9525(92)90350-D.
Article
CAS
Google Scholar
Cachon-Gonzalez MB, Fenner S, Coffin JM, Moran C, Best S, Stoye JP: Structure and expression of the hairless gene of mice. Proc Natl Acad Sci USA. 1994, 91 (16): 7717-7721. 10.1073/pnas.91.16.7717.
Article
CAS
Google Scholar
Thompson CC, Bottcher MC: The product of a thyroid hormone-responsive gene interacts with thyroid hormone receptors. Proc Natl Acad Sci USA. 1997, 94 (16): 8527-8532. 10.1073/pnas.94.16.8527.
Article
CAS
Google Scholar
Potter GB, Beaudoin GM, DeRenzo CL, Zarach JM, Chen SH, Thompson CC: The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor. Genes Dev. 2001, 15 (20): 2687-2701. 10.1101/gad.916701.
Article
CAS
Google Scholar
Hsieh JC, Sisk JM, Jurutka PW, Haussler CA, Slater SA, Haussler MR, Thompson CC: Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling. J Biol Chem. 2003, 278 (40): 38665-38674. 10.1074/jbc.M304886200.
Article
CAS
Google Scholar
Moraitis AN, Giguere V, Thompson CC: Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants. Mol Cell Biol. 2002, 22 (19): 6831-6841. 10.1128/MCB.22.19.6831-6841.2002.
Article
CAS
Google Scholar
Zarach JM, Beaudoin GM, Coulombe PA, Thompson CC: The co-repressor hairless has a role in epithelial cell differentiation in the skin. Development. 2004, 131 (17): 4189-4200. 10.1242/dev.01303.
Article
CAS
Google Scholar
Ahmad W, Panteleyev AA, Sundberg JP, Christiano AM: Molecular basis for the rhino (hrrh-8J) phenotype: a nonsense mutation in the mouse hairless gene. Genomics. 1998, 53 (3): 383-386. 10.1006/geno.1998.5495.
Article
CAS
Google Scholar
Mann SJ: Hair loss and cyst formation in hairless and rhino mutant mice. Anat Rec. 1971, 170 (4): 485-499. 10.1002/ar.1091700409.
Article
CAS
Google Scholar
Cachon-Gonzalez MB, San-Jose I, Cano A, Vega JA, Garcia N, Freeman T, Schimmang T, Stoye JP: The hairless gene of the mouse: relationship of phenotypic effects with expression profile and genotype. Dev Dyn. 1999, 216 (2): 113-126. 10.1002/(SICI)1097-0177(199910)216:2<113::AID-DVDY3>3.0.CO;2-M.
Article
CAS
Google Scholar
Brancaz MV, Iratni R, Morrison A, Mancini SJ, Marche P, Sundberg J, Nonchev S: A new allele of the mouse hairless gene interferes with Hox/LacZ transgene regulation in hair follicle primordia. Exp Mol Pathol. 2004, 76 (2): 173-181. 10.1016/j.yexmp.2003.10.003.
Article
CAS
Google Scholar
Zhang JT, Fang SG, Wang CY: A novel nonsense mutation and polymorphisms in the mouse hairless gene. J Invest Dermatol. 2005, 124 (6): 1200-1205. 10.1111/j.0022-202X.2005.23744.x.
Article
CAS
Google Scholar
Panteleyev AA, Ahmad W, Malashenko AM, Ignatieva EL, Paus R, Sundberg JP, Christiano AM: Molecular basis for the rhino Yurlovo (hr(rhY)) phenotype: severe skin abnormalities and female reproductive defects associated with an insertion in the hairless gene. Exp Dermatol. 1998, 7 (5): 281-288. 10.1111/j.1600-0625.1998.tb00298.x-i1.
Article
CAS
Google Scholar
Liu Y, Sundberg JP, Das S, Carpenter D, Cain KT, Michaud EJ, Voy BH: Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R) in the hairless gene (Hr). Vet Pathol. 47 (1): 167-176. 10.1177/0300985809352970.
Baek IC, Kim JK, Cho KH, Cha DS, Cho JW, Park JK, Song CW, Yoon SK: A novel mutation in Hr causes abnormal hair follicle morphogenesis in hairpoor mouse, an animal model for Marie Unna Hereditary Hypotrichosis. Mamm Genome. 2009, 20 (6): 350-358. 10.1007/s00335-009-9191-8.
Article
CAS
Google Scholar
Kim JK, Kim E, Baek IC, Kim BK, Cho AR, Kim TY, Song CW, Seong JK, Yoon JB, Stenn KS: Overexpression of Hr links excessive induction of Wnt signaling to Marie Unna hereditary hypotrichosis. Hum Mol Genet. 19 (3): 445-453. 10.1093/hmg/ddp509.
Wen Y, Liu Y, Xu Y, Zhao Y, Hua R, Wang K, Sun M, Li Y, Yang S, Zhang XJ, et al: Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis. Nat Genet. 2009, 41 (2): 228-233. 10.1038/ng.276.
Article
CAS
Google Scholar
Liu Y, Das S, Olszewski RE, Carpenter DA, Culiat CT, Sundberg JP, Soteropoulos P, Liu X, Doktycz MJ, Michaud EJ, et al: The near-naked hairless (Hr(N)) mutation disrupts hair formation but is not due to a mutation in the Hairless coding region. J Invest Dermatol. 2007, 127 (7): 1605-1614.
Article
CAS
Google Scholar
Andl T, Reddy ST, Gaddapara T, Millar SE: WNT signals are required for the initiation of hair follicle development. Dev Cell. 2002, 2 (5): 643-653. 10.1016/S1534-5807(02)00167-3.
Article
CAS
Google Scholar
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W: beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell. 2001, 105 (4): 533-545. 10.1016/S0092-8674(01)00336-1.
Article
CAS
Google Scholar
Beaudoin GM, Sisk JM, Coulombe PA, Thompson CC: Hairless triggers reactivation of hair growth by promoting Wnt signaling. Proc Natl Acad Sci USA. 2005, 102 (41): 14653-14658. 10.1073/pnas.0507609102.
Article
CAS
Google Scholar
Eckhart L, Ban J, Fischer H, Tschachler E: Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation. Biochem Biophys Res Commun. 2000, 277 (3): 655-659. 10.1006/bbrc.2000.3698.
Article
CAS
Google Scholar
Nishio H, Matsui K, Tsuji H, Tamura A, Suzuki K: Immunolocalisation of the janus kinases (JAK)--signal transducers and activators of transcription (STAT) pathway in human epidermis. J Anat. 2001, 198 (Pt 5): 581-589. 10.1046/j.1469-7580.2001.19850581.x.
Article
CAS
Google Scholar
Eckhart L, Declercq W, Ban J, Rendl M, Lengauer B, Mayer C, Lippens S, Vandenabeele P, Tschachler E: Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J Invest Dermatol. 2000, 115 (6): 1148-1151. 10.1046/j.1523-1747.2000.00205.x.
Article
CAS
Google Scholar
Runkel F, Klaften M, Koch K, Bohnert V, Bussow H, Fuchs H, Franz T, Hrabe de Angelis M: Morphologic and molecular characterization of two novel Krt71 (Krt2-6) mutations: Krt71rco12 and Krt71rco13. Mamm Genome. 2006, 17 (12): 1172-1182. 10.1007/s00335-006-0084-9.
Article
CAS
Google Scholar
Whitbread LA, Powell BC: Expression of the intermediate filament keratin gene K15, in the basal cell layers of epithelia and the hair follicle. Exp Cell Res. 1998, 244 (2): 448-459. 10.1006/excr.1998.4217.
Article
CAS
Google Scholar
Hamada K, Ozawa K, Itami S, Yoshikawa K: Human fibroblast growth factor 10 expression in dermal papilla cells, outer root sheath cells and keratinocytes. Exp Dermatol. 1999, 8 (4): 347-349.
CAS
PubMed
Google Scholar
Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin JS: Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci USA. 1997, 94 (13): 6770-6775. 10.1073/pnas.94.13.6770.
Article
CAS
Google Scholar
Hsieh JC, Kodjabachian L, Rebbert ML, Rattner A, Smallwood PM, Samos CH, Nusse R, Dawid IB, Nathans J: A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature. 1999, 398 (6726): 431-436. 10.1038/18899.
Article
CAS
Google Scholar
Thompson CC, Sisk JM, Beaudoin GM: Hairless and Wnt signaling: allies in epithelial stem cell differentiation. Cell Cycle. 2006, 5 (17): 1913-1917.
Article
CAS
Google Scholar
Alibardi L, Tschachler E, Eckhart L: Distribution of caspase-14 in epidermis and hair follicles is evolutionarily conserved among mammals. Anat Rec A Discov Mol Cell Evol Biol. 2005, 286 (2): 962-973.
Article
Google Scholar
Li C, Wong WH: Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci USA. 2001, 98 (1): 31-36. 10.1073/pnas.011404098.
Article
CAS
Google Scholar
Tusher VG, Tibshirani R, Chu G: Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA. 2001, 98 (9): 5116-5121. 10.1073/pnas.091062498.
Article
CAS
Google Scholar
Storey JD, Tibshirani R: Statistical significance for genomewide studies. Proc Natl Acad Sci USA. 2003, 100 (16): 9440-9445. 10.1073/pnas.1530509100.
Article
CAS
Google Scholar
Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001, 25 (4): 402-408. 10.1006/meth.2001.1262.
Article
CAS
Google Scholar