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  1. Current heart failure (HF) treatment is based on targeting symptoms and left ventricle dysfunction severity, relying on a common HF pathway paradigm to justify common treatments for HF patients. This common st...

    Authors: Mary E. Sweet, Andrea Cocciolo, Dobromir Slavov, Kenneth L. Jones, Joseph R. Sweet, Sharon L. Graw, T. Brett Reece, Amrut V. Ambardekar, Michael R. Bristow, Luisa Mestroni and Matthew R. G. Taylor
    Citation: BMC Genomics 2018 19:812
    Content type: Research article Published on:

  2. The ability of a genotype to produce different phenotypes according to its surrounding environment is known as phenotypic plasticity. Within different individuals of the same species, phenotypic plasticity can...

    Authors: Emilien Peltier, Vikas Sharma, Maria Martí Raga, Miguel Roncoroni, Margaux Bernard, Vladimir Jiranek, Yves Gibon and Philippe Marullo
    Citation: BMC Genomics 2018 19:772
    Content type: Research article Published on:

  3. Anthocyanins are water-soluble colored flavonoids present in multiple organs of various plant species including flowers, fruits, leaves, stems and roots. DNA-binding R2R3-MYB transcription factors, basic helix–lo...

    Authors: Miyako Kodama, Henrik Brinch-Pedersen, Shrikant Sharma, Inger Bæksted Holme, Bjarne Joernsgaard, Tsaneta Dzhanfezova, Daniel Buchvaldt Amby, Filipe Garrett Vieira, Shanlin Liu and M Thomas P Gilbert
    Citation: BMC Genomics 2018 19:811
    Content type: Research article Published on:

  4. Staphylococcus caprae is an animal-associated bacterium regarded as part of goats’ microflora. Recently, S. caprae has been reported to cause human nosocomial infections such as bacteremia and bone and joint infe...

    Authors: Shinya Watanabe, Yoshifumi Aiba, Xin-Ee Tan, Feng-Yu Li, Tanit Boonsiri, Kanate Thitiananpakorn, Bintao Cui, Yusuke Sato’o, Kotaro Kiga, Teppei Sasahara and Longzhu Cui
    Citation: BMC Genomics 2018 19:810
    Content type: Research article Published on:

  5. Translatomics data, particularly genome-wide ribosome profiling and polysome profiling, provide multiple levels of gene regulatory information that can be used to assess general transcription and translation, ...

    Authors: Amanda W. Ernlund, Robert J. Schneider and Kelly V. Ruggles
    Citation: BMC Genomics 2018 19:809
    Content type: Software Published on:

  6. Animal studies show that high fat (HF) diet-induced gut microbiota contributes to the development of obesity. Oil composition of high-fat diet affects metabolic inflammation differently with deleterious effect...

    Authors: Vania Patrone, Andrea Minuti, Michela Lizier, Francesco Miragoli, Franco Lucchini, Erminio Trevisi, Filippo Rossi and Maria Luisa Callegari
    Citation: BMC Genomics 2018 19:808
    Content type: Research article Published on:

  7. Alfalfa (Medicago sativa) is a widely cultivated, essential commercial forage crop. The protein content in its leaves is the critical factor in determining the quality of alfalfa. Thus far, the understanding of t...

    Authors: Qiming Cheng, Shiqie Bai, Gentu Ge, Ping Li, Liying Liu, Chengdong Zhang and Yushan Jia
    Citation: BMC Genomics 2018 19:807
    Content type: Research article Published on:

  8. Rapeseed (Brassica napus) is an important oil seed crop in the Brassicaceae family. Chemical induced male sterility (CIMS) is one of the widely used method to produce the hybrids in B. napus. Identification of th...

    Authors: Luyun Ning, Zhiwei Lin, Jianwei Gu, Lu Gan, Yonghong Li, Hao Wang, Liyun Miao, Libin Zhang, Baoshan Wang and Maoteng Li
    Citation: BMC Genomics 2018 19:806
    Content type: Research article Published on:

  9. Long non-coding RNAs (lncRNAs) are involved in variable cleavage, transcriptional interference, regulation of DNA methylation and protein modification. However, the regulation of lncRNAs in plant somatic embry...

    Authors: Yan Chen, Xue Li, Liyao Su, Xu Chen, Shuting Zhang, Xiaoping Xu, Zihao Zhang, Yukun Chen, Xu XuHan, Yuling Lin and Zhongxiong Lai
    Citation: BMC Genomics 2018 19:805
    Content type: Research article Published on:

  10. A change in the environment may impair development or survival of living organisms leading them to adapt to the change. The resulting adaptation trait may reverse, or become fixed in the population leading to ...

    Authors: Yves Moné, Sandra Nhim, Sylvie Gimenez, Fabrice Legeai, Imène Seninet, Hugues Parrinello, Nicolas Nègre and Emmanuelle d’Alençon
    Citation: BMC Genomics 2018 19:804
    Content type: Research article Published on:

  11. WD40 domains are abundant in eukaryotes, and they are essential subunits of large multiprotein complexes, which serve as scaffolds. WD40 proteins participate in various cellular processes, such as histone modi...

    Authors: Rui Hu, Jie Xiao, Ting Gu, Xiaofen Yu, Yang Zhang, Junli Chang, Guangxiao Yang and Guangyuan He
    Citation: BMC Genomics 2018 19:803
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Genomics 2018 19:852

  12. Epithelial–mesenchymal transition (EMT) is regarded as a critical event during tumor metastasis. Recent studies have revealed changes and the contributions of proteins in/on exosomes during EMT. Besides protei...

    Authors: Yue-Ting Tang, Yi-Yao Huang, Jing-Huan Li, Si-Hua Qin, Yong Xu, Tai-Xue An, Chun-Chen Liu, Qian Wang and Lei Zheng
    Citation: BMC Genomics 2018 19:802
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:753

  13. Salmonella enterica is a significant foodborne pathogen, which can be transmitted via several distinct routes, and reports on acquisition of antimicrobial resistance (AMR) are increasing. To better understand the...

    Authors: Suchawan Pornsukarom, Arnoud H M van Vliet and Siddhartha Thakur
    Citation: BMC Genomics 2018 19:801
    Content type: Research article Published on:

  14. Calanthe masuca and C. sinica are two genetically closely related species in Orchidaceae. C. masuca is widely distributed in Asia, whereas C. sinica is restricted to Yunnan and Guangxi Provinces in southwest Chin...

    Authors: Chao Hu, Hongxing Yang, Kai Jiang, Ling Wang, Boyun Yang, Tungyu Hsieh, Siren Lan and Weichang Huang
    Citation: BMC Genomics 2018 19:800
    Content type: Research article Published on:

  15. Count data derived from high-throughput deoxy-ribonucliec acid (DNA) sequencing is frequently used in quantitative molecular assays. Due to properties inherent to the sequencing process, unnormalized count dat...

    Authors: M. Senthil Kumar, Eric V. Slud, Kwame Okrah, Stephanie C. Hicks, Sridhar Hannenhalli and Héctor Corrada Bravo
    Citation: BMC Genomics 2018 19:799
    Content type: Methodology article Published on:

  16. Next-generation sequencing requires sufficient DNA to be available. If limited, whole-genome amplification is applied to generate additional amounts of DNA. Such amplification often results in many chimeric DN...

    Authors: Sven Warris, Elio Schijlen, Henri van de Geest, Rahulsimham Vegesna, Thamara Hesselink, Bas te Lintel Hekkert, Gabino Sanchez Perez, Paul Medvedev, Kateryna D. Makova and Dick de Ridder
    Citation: BMC Genomics 2018 19:798
    Content type: Research article Published on:

  17. Ornamental cabbage (Brassica oleracea var. acephala) is an attractive landscape plant that remains colorful at low temperatures during winter. Its key feature is its inner leaf coloration, which can include red, ...

    Authors: Si-Won Jin, Md Abdur Rahim, Khandker Shazia Afrin, Jong-In Park, Jong-Goo Kang and Ill-Sup Nou
    Citation: BMC Genomics 2018 19:797
    Content type: Research article Published on:

  18. Dependence on marine natural resources threatens the sustainability of Atlantic salmon aquaculture. In the present study, Atlantic salmon fed for 14 weeks with an experimental diet based on animal by-products ...

    Authors: Albert Caballero-Solares, Xi Xue, Christopher C. Parrish, Maryam Beheshti Foroutani, Richard G. Taylor and Matthew L. Rise
    Citation: BMC Genomics 2018 19:796
    Content type: Research article Published on:

  19. Development of the face and mouth is orchestrated by a large number of transcription factors, signaling pathways and epigenetic regulators. While we know many of these regulators, our understanding of how they...

    Authors: Stacey E. Wahl, Brent H. Wyatt, Stephen D. Turner and Amanda J. G. Dickinson
    Citation: BMC Genomics 2018 19:795
    Content type: Research article Published on:

  20. Norepinephrine (NE) signaling has a key role in white adipose tissue (WAT) functions, including lipolysis, free fatty acid liberation and, under certain conditions, conversion of white into brite (brown-in-whi...

    Authors: Juan Carlos Higareda-Almaraz, Michael Karbiener, Maude Giroud, Florian M. Pauler, Teresa Gerhalter, Stephan Herzig and Marcel Scheideler
    Citation: BMC Genomics 2018 19:794
    Content type: Research article Published on:

  21. The mutations changing the expression level of a gene, or expression quantitative trait loci (eQTL), can be identified by testing the association between genetic variants and gene expression in multiple indivi...

    Authors: Majid Khansefid, Jennie E. Pryce, Sunduimijid Bolormaa, Yizhou Chen, Catriona A. Millen, Amanda J. Chamberlain, Christy J. Vander Jagt and Michael E. Goddard
    Citation: BMC Genomics 2018 19:793
    Content type: Research article Published on:

  22. Understanding how and why genetic variation is partitioned across geographic space is of fundamental importance to understanding the nature of biological species. How geographical isolation and local adaptatio...

    Authors: Billie A. Gould, Juan Diego Palacio-Mejia, Jerry Jenkins, Sujan Mamidi, Kerrie Barry, Jeremy Schmutz, Thomas E. Juenger and David B. Lowry
    Citation: BMC Genomics 2018 19:792
    Content type: Research article Published on:

  23. Feed efficiency (FE) is an indicator of efficiency in converting energy and nutrients from feed into a tissue that is of major environmental and economic significance. The molecular mechanisms contributing to ...

    Authors: Justyna Horodyska, Klaus Wimmers, Henry Reyer, Nares Trakooljul, Anne Maria Mullen, Peadar G. Lawlor and Ruth M. Hamill
    Citation: BMC Genomics 2018 19:791
    Content type: Research article Published on:

  24. Although human leukocyte antigen (HLA) genotyping based on amplicon, whole exome sequence (WES), and RNA sequence data has been achieved in recent years, accurate genotyping from whole genome sequence (WGS) da...

    Authors: Shuto Hayashi, Rui Yamaguchi, Shinichi Mizuno, Mitsuhiro Komura, Satoru Miyano, Hidewaki Nakagawa and Seiya Imoto
    Citation: BMC Genomics 2018 19:790
    Content type: Methodology article Published on:

  25. Hypsizygus marmoreus (Beech mushroom) is a popular ingredient in Asian cuisine. The medicinal effects of its bioactive compounds such as hypsin and hypsiziprenol have been reported, but the genetic basis or biosy...

    Authors: Byoungnam Min, Seunghwan Kim, Youn-Lee Oh, Won-Sik Kong, Hongjae Park, Heejung Cho, Kab-Yeul Jang, Jeong-Gu Kim and In-Geol Choi
    Citation: BMC Genomics 2018 19:789
    Content type: Research article Published on:

  26. The insect olfactory system is a highly specific and sensitive chemical detector, which plays important roles in feeding, mating and finding an appropriate oviposition site. The ecological niche of Bombyx mori ha...

    Authors: Chuan-Zhen Qiu, Qiu-Zhong Zhou, Ting-Ting Liu, Shou-Min Fang, Ya-Wang Wang, Xin Fang, Chun-Li Huang, Quan-You Yu, Chun-Hong Chen and Ze Zhang
    Citation: BMC Genomics 2018 19:788
    Content type: Research article Published on:

  27. Macaca fascicularis (M. fascicularis) is a primate model organism that played important role in studying human health. It is vital to better understand the similarity and differences of gene regulation between M....

    Authors: Tao Tan, Lin Xia, Kailing Tu, Jie Tang, Senlin Yin, Lunzhi Dai, Peng Lei, Biao Dong, Hongbo Hu, Yong Fan, Yang Yu and Dan Xie
    Citation: BMC Genomics 2018 19:787
    Content type: Research article Published on:

  28. Fusion genes are known to be drivers of many common cancers, so they are potential markers for diagnosis, prognosis or therapy response. The advent of paired-end RNA sequencing enhances our ability to discover...

    Authors: Trung Nghia Vu, Wenjiang Deng, Quang Thinh Trac, Stefano Calza, Woochang Hwang and Yudi Pawitan
    Citation: BMC Genomics 2018 19:786
    Content type: Methodology article Published on:

  29. The aim of this study was to analyze potential influences of polymorphisms within the regulatory region of the bovine SIRT6 gene on carcass quality traits. Expression analyses suggested that SIRT6 gene is pred...

    Authors: Lin-sheng Gui, Sayed Haidar Abbas Raza, Matthew Garcia, Yong-gang Sun, Irfan Ullah and Yin-cang Han
    Citation: BMC Genomics 2018 19:785
    Content type: Research article Published on:

  31. Our previous study showed that (+)-cholesten-3-one (CN) has the potential to induce the osteoblastic differentiation of mesenchymal stem cells (MSCs). However, the roles of CN in targeting miRNA-mRNA-lncRNA in...

    Authors: Qiuke Hou, Yongquan Huang, Yamei Liu, Yiwen Luo, Bin Wang, Rudong Deng, Saixia Zhang, Fengbin Liu and Dongfeng Chen
    Citation: BMC Genomics 2018 19:783
    Content type: Research article Published on:

  32. Dickeya sp. strain PA1 is the causal agent of bacterial soft rot in Phalaenopsis, an important indoor orchid in China. PA1 and a few other strains were grouped into a novel species, Dickeya fangzhongdai, and only...

    Authors: Jingxin Zhang, John Hu, Huifang Shen, Yucheng Zhang, Dayuan Sun, Xiaoming Pu, Qiyun Yang, Qiurong Fan and Birun Lin
    Citation: BMC Genomics 2018 19:782
    Content type: Research article Published on:

  33. Bacterial filamentation occurs when rod-shaped bacteria grow without dividing. To identify genetically encoded inhibitors of division that promote filamentation, we used cell sorting flow cytometry to enrich f...

    Authors: Daniel G. Mediati, Catherine M. Burke, Shirin Ansari, Elizabeth J. Harry and Iain G. Duggin
    Citation: BMC Genomics 2018 19:781
    Content type: Research article Published on:

  34. The molecular mechanism controlling regional specific skin appendage phenotypes is a fundamental question that remains unresolved. We recently identified feather and scale primordium associated genes and with ...

    Authors: Yung-Chih Lai, Ya-Chen Liang, Ting-Xin Jiang, Randall B. Widelitz, Ping Wu and Cheng-Ming Chuong
    Citation: BMC Genomics 2018 19:780
    Content type: Research article Published on:

  35. MicroRNAs (miRNAs) are endogenous, small (21–25 nucleotide), non-coding RNAs that play important roles in numerous biological processes. Koi carp exhibit diverse color patterns, making it an ideal subject for ...

    Authors: Mingkun Luo, Lanmei Wang, Wenbin Zhu, Jianjun Fu, Feibiao Song, Min Fang, Juanjuan Dong and Zaijie Dong
    Citation: BMC Genomics 2018 19:779
    Content type: Research article Published on:

  36. Understanding the underlying genetic structure of human populations is of fundamental interest to both biological and social sciences. Advances in high-throughput genotyping technology have markedly improved o...

    Authors: Zoltán Maróti, Zsolt Boldogkői, Dóra Tombácz, Michael Snyder and Tibor Kalmár
    Citation: BMC Genomics 2018 19:778
    Content type: Methodology article Published on:

  37. Disrupted diurnal rhythms cause accelerated aging and an increased incidence in age-related disease and morbidity. The circadian clock governs cell physiology and metabolism by controlling transcription and ch...

    Authors: Jinhee Park and William J. Belden
    Citation: BMC Genomics 2018 19:777
    Content type: Research article Published on:

  38. Heterosis, a multigenic complex trait extrapolated as sum total of many phenotypic features, is widely utilized phenomenon in agricultural crops for about a century. It is mainly focused on establishing vigoro...

    Authors: Zareen Sarfraz, Muhammad Shahid Iqbal, Zhaoe Pan, Yinhua Jia, Shoupu He, Qinglian Wang, Hongde Qin, Jinhai Liu, Hui Liu, Jun Yang, Zhiying Ma, Dongyong Xu, Jinlong Yang, Jinbiao Zhang, Wenfang Gong, Xiaoli Geng…
    Citation: BMC Genomics 2018 19:776
    Content type: Research article Published on:

  39. The mitochondrial genomes of higher plants vary remarkably in size, structure and sequence content, as demonstrated by the accumulation and activity of repetitive DNA sequences. Incompatibility between mitocho...

    Authors: Shuangshuang Li, Zhiwen Chen, Nan Zhao, Yumei Wang, Hushuai Nie and Jinping Hua
    Citation: BMC Genomics 2018 19:775
    Content type: Research article Published on:

  41. Numerous protocols for viral enrichment and genome amplification have been created. However, the direct identification of viral genomes from clinical specimens using next-generation sequencing (NGS) still has ...

    Authors: Dan Zhang, Xiuyu Lou, Hao Yan, Junhang Pan, Haiyan Mao, Hongfeng Tang, Yan Shu, Yun Zhao, Lei Liu, Junping Li, Jiang Chen, Yanjun Zhang and Xuejun Ma
    Citation: BMC Genomics 2018 19:773
    Content type: Research article Published on:

  43. Trypanosoma conorhini and Trypanosoma rangeli, like Trypanosoma cruzi, are kinetoplastid protist parasites of mammals displaying divergent hosts, geographic ranges and lifestyles. Largely nonpathogenic T. rangeli

    Authors: Katie R Bradwell, Vishal N Koparde, Andrey V Matveyev, Myrna G Serrano, João M P Alves, Hardik Parikh, Bernice Huang, Vladimir Lee, Oneida Espinosa-Alvarez, Paola A Ortiz, André G Costa-Martins, Marta M G Teixeira and Gregory A Buck
    Citation: BMC Genomics 2018 19:770
    Content type: Research article Published on:

  45. Wheat (Triticum aestivum L.) is one of the world’s most important grain crops. The amyloplast, a specialized organelle, is the major site for starch synthesis and storage in wheat grain. Understanding the metabol...

    Authors: Dongyun Ma, Xin Huang, Junfeng Hou, Ying Ma, Qiaoxia Han, Gege Hou, Chenyang Wang and Tiancai Guo
    Citation: BMC Genomics 2018 19:768
    Content type: Research article Published on:

  46. Small RNAs (sRNAs) are noncoding molecules that regulate different cellular activities in several bacteria. The role of sRNAs in gene expression regulation is poorly characterized in the etiological agent of p...

    Authors: Tiago Ebert Fritsch, Franciele Maboni Siqueira and Irene Silveira Schrank
    Citation: BMC Genomics 2018 19:767
    Content type: Research article Published on:

  47. The cattle gastrointestinal tract (GIT) is the main enterohemorrhagic Escherichia coli (EHEC) reservoir. In order to identify nutrients required for the survival or multiplication of EHEC in the bovine GIT, we co...

    Authors: Audrey Segura, Marine Bertoni, Pauline Auffret, Christophe Klopp, Olivier Bouchez, Clémence Genthon, Alexandra Durand, Yolande Bertin and Evelyne Forano
    Citation: BMC Genomics 2018 19:766
    Content type: Research article Published on:

  48. A major hallmark of multicellular evolution is increasing complexity by the evolution of new specialized cell types. During Dictyostelid evolution novel specialization occurred within taxon group 4. We here ai...

    Authors: Koryu Kin, Gillian Forbes, Andrew Cassidy and Pauline Schaap
    Citation: BMC Genomics 2018 19:764
    Content type: Research article Published on:

  49. The relationship between aging and epigenetic profiles has been highlighted in many recent studies. Models using somatic cell methylomes to predict age have been successfully constructed. However, gamete aging...

    Authors: Timothy G. Jenkins, Kenneth I. Aston, Bradley Cairns, Andrew Smith and Douglas T. Carrell
    Citation: BMC Genomics 2018 19:763
    Content type: Research article Published on:

  50. Ural genetic family is a part of the Euro-American lineage of Mycobacterium tuberculosis and is endemic in Northern Eurasia (former Soviet Union [FSU]). These strains were long described as drug susceptible and o...

    Authors: Viacheslav Sinkov, Oleg Ogarkov, Igor Mokrousov, Yuri Bukin, Svetlana Zhdanova and Scott K. Heysell
    Citation: BMC Genomics 2018 19:762
    Content type: Research article Published on:

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BMC Genomics

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