Skip to main content

Articles

Page 223 of 338

  1. Bovine tuberculosis (bTB) is a disease with major implications for animal welfare and productivity, as well as having the potential for zoonotic transmission. In Great Britain (GB) alone, controlling bTB costs...

    Authors: Paul Golby, Javier Nunez, Adam Witney, Jason Hinds, Michael A Quail, Stephen Bentley, Simon Harris, Noel Smith, R Glyn Hewinson and Stephen V Gordon
    Citation: BMC Genomics 2013 14:710
    Content type: Research article Published on:

  2. Conopeptides, often generically referred to as conotoxins, are small neurotoxins found in the venom of predatory marine cone snails. These molecules are highly stable and are able to efficiently and selectivel...

    Authors: Vincent Lavergne, Sébastien Dutertre, Ai-hua Jin, Richard J Lewis, Ryan J Taft and Paul F Alewood
    Citation: BMC Genomics 2013 14:708
    Content type: Methodology article Published on:

  3. Competition between bacteria for habitat and resources is very common in the natural environment and is considered to be a selective force for survival. Many strains of the genus Pseudoalteromonas were confirmed ...

    Authors: Min Yu, Kaihao Tang, Jiwen Liu, Xiaochong Shi, Tobias AM Gulder and Xiao-Hua Zhang
    Citation: BMC Genomics 2013 14:707
    Content type: Research article Published on:

  4. MicroRNAs (miRNAs) are small, endogenously expressed, non-coding RNA molecules involved in gene transcription and expression that combine with specific mRNA site of target genes to inhibit protein synthesis or...

    Authors: Xuemei Chen, Wenhui Gao, Jinfa Zhang, Xianlong Zhang and Zhongxu Lin
    Citation: BMC Genomics 2013 14:706
    Content type: Research article Published on:

  5. MicroRNAs (miRNAs) are key components in post-transcriptional gene regulation in multicellular organisms. As they control cooperatively a large number of their target genes, they affect the complexity of gene ...

    Authors: Young-Ji Na and Ju Han Kim
    Citation: BMC Genomics 2013 14(Suppl 5):S17
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  6. Metagenomics seeks to understand microbial communities and assemblages by DNA sequencing. Technological advances in next generation sequencing technologies are fuelling a rapid growth in the number and scope o...

    Authors: Suparna Mitra, Karin Förster-Fromme, Antje Damms-Machado, Tim Scheurenbrand, Saskia Biskup, Daniel H Huson and Stephan C Bischoff
    Citation: BMC Genomics 2013 14(Suppl 5):S16
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  7. Many biological processes are carried out by proteins interacting with each other in the form of protein complexes. However, large-scale detection of protein complexes has remained constrained by experimental ...

    Authors: Daniel Lin-Kit Wong, Xiao-Li Li, Min Wu, Jie Zheng and See-Kiong Ng
    Citation: BMC Genomics 2013 14(Suppl 5):S15
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  8. As the output of biological assays increase in resolution and volume, the body of specialized biological data, such as functional annotations of gene and protein sequences, enables extraction of higher-level k...

    Authors: Lars Rønn Olsen, Ulrich Johan Kudahl, Ole Winther and Vladimir Brusic
    Citation: BMC Genomics 2013 14(Suppl 5):S14
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  9. Small bioinformatics databases, unlike institutionally funded large databases, are vulnerable to discontinuation and many reported in publications are no longer accessible. This leads to irreproducible scienti...

    Authors: Tin Wee Tan, Chao Xie, Mark De Silva, Kuan Siong Lim, C Pawan K Patro, Shen Jean Lim, Kunde Ramamoorthy Govindarajan, Joo Chuan Tong, Khar Heng Choo, Shoba Ranganathan and Asif M Khan
    Citation: BMC Genomics 2013 14(Suppl 5):S13
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  10. MicroRNAs (miRNAs) are short noncoding RNAs (approximately 22 nucleotides in length) that play important roles in colorectal cancer (CRC) progression through silencing gene expression. Numerous dysregulated miRNA...

    Authors: Wei-Shone Chen, Ting-Wen Chen, Tzu-Hsien Yang, Ling-Yueh Hu, Hung-Wei Pan, Chung-Man Leung, Sung-Chou Li, Meng-Ru Ho, Chih-Wen Shu, Pei-Feng Liu, Shou-Yu Yu, Ya-Ting Tu, Wen-Chang Lin, Tony T Wu and Kuo-Wang Tsai
    Citation: BMC Genomics 2013 14(Suppl 5):S12
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  11. Computational methods for the prediction of Major Histocompatibility Complex (MHC) class II binding peptides play an important role in facilitating the understanding of immune recognition and the process of ep...

    Authors: Linyuan Guo, Cheng Luo and Shanfeng Zhu
    Citation: BMC Genomics 2013 14(Suppl 5):S11
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  12. Schizophrenic patients show lower incidences of cancer, implicating schizophrenia may be a protective factor against cancer. To study the genetic correlation between the two diseases, a specific PPI network wa...

    Authors: Kuo-Chuan Huang, Ko-Chun Yang, Han Lin, Theresa Tsao Tsun-Hui, Wen-Kuei Lee, Sheng-An Lee and Cheng-Yan Kao
    Citation: BMC Genomics 2013 14(Suppl 5):S10
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  13. The large-scale sequencing of 5' cap enriched cDNA promises to reveal the diversity of transcription initiation across entire genomes. The process of transcription is noisy, and there is often no single, exact...

    Authors: Dario Strbenac, Nicola J Armstrong and Jean YH Yang
    Citation: BMC Genomics 2013 14(Suppl 5):S9
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

    The Erratum to this article has been published in BMC Genomics 2013 14:767

  14. Human aneuploidy is the leading cause of early pregnancy loss, mental retardation, and multiple congenital anomalies. Due to the high mortality associated with aneuploidy, the pathophysiological mechanisms of ...

    Authors: Ruosi Zhang, Lili Hao, Lingping Wang, Meili Chen, Wen Li, Rujiao Li, Jun Yu, Jingfa Xiao and Jiayan Wu
    Citation: BMC Genomics 2013 14(Suppl 5):S8
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  15. Plant cell wall-degrading enzymes (PCWDEs) play significant roles throughout the fungal life including acquisition of nutrients and decomposition of plant cell walls. In addition, many of PCWDEs are also utili...

    Authors: Jaeyoung Choi, Ki-Tae Kim, Jongbum Jeon and Yong-Hwan Lee
    Citation: BMC Genomics 2013 14(Suppl 5):S7
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  16. Coffee contains several compounds that have the potential to influence breast cancer risk and survival. However, epidemiologic data on the relation between coffee compounds and breast cancer survival are spars...

    Authors: Babita Shashni, Karun Sharma, Rumani Singh, Kishore R Sakharkar, Sarinder K Dhillon, Yukio Nagasaki and Meena K Sakharkar
    Citation: BMC Genomics 2013 14(Suppl 5):S6
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  17. The adaptive immune response is antigen-specific and triggered by pathogen recognition through T cells. Although the interactions and mechanisms of TCR-peptide-MHC (TCR-pMHC) have been studied over three decad...

    Authors: I-Hsin Liu, Yu-Shu Lo and Jinn-Moon Yang
    Citation: BMC Genomics 2013 14(Suppl 5):S5
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  18. Recent discovery in tumor development indicates that the tumor microenvironment (mostly stroma cells) plays an important role in cancer development. To understand how the tumor microenvironment (TME) interacts...

    Authors: Yang Xiang, Jie Zhang and Kun Huang
    Citation: BMC Genomics 2013 14(Suppl 5):S4
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  19. While more and more long intergenic non-coding RNAs (lincRNAs) were identified to take important roles in both maintaining pluripotency and regulating differentiation, how these lincRNAs may define and drive c...

    Authors: Xing Tang, Mei Hou, Yang Ding, Zhaohui Li, Lichen Ren and Ge Gao
    Citation: BMC Genomics 2013 14(Suppl 5):S3
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  20. Cell type and TF specific interactions between Transcription Factors (TFs) and cofactors are essential for transcriptional regulation through recruitment of general transcription machinery to gene promoter reg...

    Authors: Chin Lui Goi, Peter Little and Chao Xie
    Citation: BMC Genomics 2013 14(Suppl 5):S2
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 5

  21. Prosopis alba (Fabaceae) is an important native tree adapted to arid and semiarid regions of north-western Argentina which is of great value as multipurpose species. Despite its importance, the genomic resources ...

    Authors: Susana L Torales, Máximo Rivarola, María F Pomponio, Sergio Gonzalez, Cintia V Acuña, Paula Fernández, Diego L Lauenstein, Aníbal R Verga, H Esteban Hopp, Norma B Paniego and Susana N Marcucci Poltri
    Citation: BMC Genomics 2013 14:705
    Content type: Research article Published on:

  22. Animal and plant genomes produce numerous small RNAs (smRNAs) that regulate gene expression post-transcriptionally affecting metabolism, development, and epigenetic inheritance. In order to characterize the re...

    Authors: Sebastian Baumgarten, Till Bayer, Manuel Aranda, Yi Jin Liew, Adrian Carr, Gos Micklem and Christian R Voolstra
    Citation: BMC Genomics 2013 14:704
    Content type: Research article Published on:

  23. G-protein coupled receptors (GPCRs) play an inordinately large role in human health. Variation in the genes that encode these receptors is associated with numerous disorders across the entire spectrum of disea...

    Authors: Dharmendra B Goswami, Lisa M Ogawa, Joshua M Ward, Gregory M Miller and Eric J Vallender
    Citation: BMC Genomics 2013 14:703
    Content type: Research article Published on:

  24. EST (expressed sequence tag) sequences and their annotation provide a highly valuable resource for gene discovery, genome sequence annotation, and other genomics studies that can be applied in genetics, breedi...

    Authors: Ishminder K Mann, Jill L Wegrzyn and Om P Rajora
    Citation: BMC Genomics 2013 14:702
    Content type: Research article Published on:

  25. Nitrate and other nitrogen metabolites can act as signals that regulate global gene expression in plants. Adaptive changes in plant morphology and physiology triggered by changes in nitrate availability are pa...

    Authors: Elena A Vidal, Tomás C Moyano, Gabriel Krouk, Manpreet S Katari, Milos Tanurdzic, W Richard McCombie, Gloria M Coruzzi and Rodrigo A Gutiérrez
    Citation: BMC Genomics 2013 14:701
    Content type: Research article Published on:

  26. Insertion Sequences (ISs) and their non-autonomous derivatives (MITEs) are important components of prokaryotic genomes inducing duplication, deletion, rearrangement or lateral gene transfers. Although ISs and ...

    Authors: Choumouss Kamoun, Thibaut Payen, Aurélie Hua-Van and Jonathan Filée
    Citation: BMC Genomics 2013 14:700
    Content type: Methodology article Published on:

  27. Accurate bacterial genome annotations provide a framework to understanding cellular functions, behavior and pathogenicity and are essential for metabolic engineering. Annotations based only on in silico predictio...

    Authors: Esteban Marcellin, Cuauhtemoc Licona-Cassani, Tim R Mercer, Robin W Palfreyman and Lars K Nielsen
    Citation: BMC Genomics 2013 14:699
    Content type: Research article Published on:

  28. Mercury is a ubiquitous environmental toxicant that exists in multiple chemical forms. A paucity of information exists regarding the differences or similarities by which different mercurials act at the molecul...

    Authors: Matthew K McElwee, Lindsey A Ho, Jeff W Chou, Marjolein V Smith and Jonathan H Freedman
    Citation: BMC Genomics 2013 14:698
    Content type: Research article Published on:

  29. The white shark (Carcharodon carcharias) is a globally distributed, apex predator possessing physical, physiological, and behavioral traits that have garnered it significant public attention. In addition to inter...

    Authors: Vincent P Richards, Haruo Suzuki, Michael J Stanhope and Mahmood S Shivji
    Citation: BMC Genomics 2013 14:697
    Content type: Research article Published on:

  30. MicroRNAs (miRNAs) have recently been shown to play important roles in development of the immune system and in fine-tuning of immune responses. Human miR-146 family members are known as inflammation-inducible ...

    Authors: Anita Ordas, Zakia Kanwal, Valesca Lindenberg, Julien Rougeot, Matyas Mink, Herman P Spaink and Annemarie H Meijer
    Citation: BMC Genomics 2013 14:696
    Content type: Research article Published on:

  31. The dimorphic fungus Histoplasma capsulatum causes respiratory and systemic disease in mammalian hosts by expression of factors that enable survival within phagocytic cells of the immune system. Histoplasma’s dim...

    Authors: Jessica A Edwards, Chenxi Chen, Megan M Kemski, Jinnan Hu, Thomas K Mitchell and Chad A Rappleye
    Citation: BMC Genomics 2013 14:695
    Content type: Research article Published on:

  32. The initial interaction between host cell and pathogen sets the stage for the ensuing infection and ultimately determine the course of disease. However, there is limited knowledge of the transcripts utilized b...

    Authors: Elise A Lamont, Wayne W Xu and Srinand Sreevatsan
    Citation: BMC Genomics 2013 14:694
    Content type: Research article Published on:

  33. Lyme disease is caused by spirochete bacteria from the Borrelia burgdorferi sensu lato (B. burgdorferi s.l.) species complex. To reconstruct the evolution of B. burgdorferi s.l. and identify the genomic basis of ...

    Authors: Emmanuel F Mongodin, Sherwood R Casjens, John F Bruno, Yun Xu, Elliott Franco Drabek, David R Riley, Brandi L Cantarel, Pedro E Pagan, Yozen A Hernandez, Levy C Vargas, John J Dunn, Steven E Schutzer, Claire M Fraser, Wei-Gang Qiu and Benjamin J Luft
    Citation: BMC Genomics 2013 14:693
    Content type: Research article Published on:

  34. CpG dinucleotide-rich genomic DNA regions, known as CpG islands (CGIs), can be methylated at their cytosine residues as an epigenetic mark that is stably inherited during cell mitosis. Differentially methylate...

    Authors: Sergio Cocozza, Giovanni Scala, Gennaro Miele, Imma Castaldo and Antonella Monticelli
    Citation: BMC Genomics 2013 14:692
    Content type: Research article Published on:

  35. Different from herbaceous plants, the woody plants undergo a long-period vegetative stage to achieve floral transition. They then turn into seasonal plants, flowering annually. In this study, a preliminary mod...

    Authors: You-Jun Huang, Li-Li Liu, Jian-Qin Huang, Zheng-Jia Wang, Fang-Fang Chen, Qi-Xiang Zhang, Bing-Song Zheng and Ming Chen
    Citation: BMC Genomics 2013 14:691
    Content type: Research article Published on:

  36. The Oncotype DX® Prostate Cancer Assay is a multi-gene RT-PCR expression assay that was developed for use with fixed paraffin-embedded (FPE) diagnostic prostate needle biopsies containing as little as 1 mm of pro...

    Authors: Dejan Knezevic, Audrey D Goddard, Nisha Natraj, Diana B Cherbavaz, Kim M Clark-Langone, Jay Snable, Drew Watson, Sara M Falzarano, Cristina Magi-Galluzzi, Eric A Klein and Christopher Quale
    Citation: BMC Genomics 2013 14:690
    Content type: Methodology article Published on:

  37. The species Brassica rapa (2n=20, AA) is an important vegetable and oilseed crop, and serves as an excellent model for genomic and evolutionary research in Brassica species. With the availability of whole genome ...

    Authors: Chaobo Tong, Xiaowu Wang, Jingyin Yu, Jian Wu, Wanshun Li, Junyan Huang, Caihua Dong, Wei Hua and Shengyi Liu
    Citation: BMC Genomics 2013 14:689
    Content type: Research article Published on:

  40. Soybean is an important crop that provides valuable proteins and oils for human use. Because soybean growth and development is extremely sensitive to water deficit, quality and crop yields are severely impacte...

    Authors: Li M Chen, Xin A Zhou, Wen B Li, Wei Chang, Rong Zhou, Cheng Wang, Ai H Sha, Zhi H Shan, Chan J Zhang, De Z Qiu, Zhong L Yang and Shui L Chen
    Citation: BMC Genomics 2013 14:687
    Content type: Research article Published on:

  41. Next generation sequencing provides a powerful tool to study genome structure in species whose genomes are far from being completely sequenced. In this work we describe and compare different computational appr...

    Authors: Lucia Natali, Rosa Maria Cossu, Elena Barghini, Tommaso Giordani, Matteo Buti, Flavia Mascagni, Michele Morgante, Navdeep Gill, Nolan C Kane, Loren Rieseberg and Andrea Cavallini
    Citation: BMC Genomics 2013 14:686
    Content type: Research article Published on:

  42. Genomic imprinting is an epigenetically regulated process wherein genes are expressed in a parent-of-origin specific manner. Many imprinted genes were initially identified in mice; some of these were subsequen...

    Authors: Radhika Das, Yew Kok Lee, Ruslan Strogantsev, Shengnan Jin, Yen Ching Lim, Poh Yong Ng, Xueqin Michelle Lin, Keefe Chng, George SH Yeo, Anne C Ferguson-Smith and Chunming Ding
    Citation: BMC Genomics 2013 14:685
    Content type: Research article Published on:

  43. Serum alkaline phosphatase (ALP) is a complex phenotype influenced by both genetic and environmental factors. Recent Genome-Wide Association Studies (GWAS) have identified several loci affecting ALP levels; ho...

    Authors: Jun Li, Lixuan Gui, Chen Wu, Yunfeng He, Li Zhou, Huan Guo, Jing Yuan, Binyao Yang, Xiayun Dai, Qifei Deng, Suli Huang, Lei Guan, Die Hu, Siyun Deng, Tian Wang, Jiang Zhu…
    Citation: BMC Genomics 2013 14:684
    Content type: Research article Published on:

  44. Modern banana cultivars are primarily interspecific triploid hybrids of two species, Musa acuminata and Musa balbisiana, which respectively contribute the A- and B-genomes. The M. balbisiana genome has been assoc...

    Authors: Mark W Davey, Ranganath Gudimella, Jennifer Ann Harikrishna, Lee Wan Sin, Norzulaani Khalid and Johan Keulemans
    Citation: BMC Genomics 2013 14:683
    Content type: Research article Published on:

  45. Amur ide (Leuciscus waleckii) is an economically and ecologically important cyprinid species in Northern Asia. The Dali Nor population living in the soda lake Dali Nor can adapt the extremely high alkalinity, pro...

    Authors: Jian Xu, Qiang Li, Liming Xu, Shaolin Wang, Yanliang Jiang, Zixia Zhao, Yan Zhang, Jiongtang Li, Chuanju Dong, Peng Xu and Xiaowen Sun
    Citation: BMC Genomics 2013 14:682
    Content type: Research article Published on:

  46. Variation of gene expression can lead to phenotypic variation and have therefore been assumed to contribute the diversity of wine yeast (Saccharomyces cerevisiae) properties. However, the molecular bases of this ...

    Authors: Christian Brion, Chloé Ambroset, Isabelle Sanchez, Jean-Luc Legras and Bruno Blondin
    Citation: BMC Genomics 2013 14:681
    Content type: Research article Published on:

  47. The epithelial-to-mesenchymal transition is an important mechanism in cancer metastasis. Although transcription factors including SNAIL, SLUG, and TWIST1 regulate the epithelial-to-mesenchymal transition, othe...

    Authors: Haiyun Wang, Clifford A Meyer, Teng Fei, Gang Wang, Fan Zhang and X Shirley Liu
    Citation: BMC Genomics 2013 14:680
    Content type: Research article Published on:

  48. The advent of next-generation high-throughput technologies has revolutionized whole genome sequencing, yet some experiments require sequencing only of targeted regions of the genome from a very large number of...

    Authors: Wenwei Xiong, Limei He, Yubin Li, Hugo K Dooner and Chunguang Du
    Citation: BMC Genomics 2013 14:679
    Content type: Software Published on:

  49. Shigella flexneri is the major cause of shigellosis in the developing countries. The O-antigen component of the lipopolysaccharide is one of the key virulence determinants required for the pathogenesis of S. flex...

    Authors: Richa Jakhetia, Kaisar A Talukder and Naresh K Verma
    Citation: BMC Genomics 2013 14:677
    Content type: Research article Published on:

  50. With the price of next generation sequencing steadily decreasing, bacterial genome assembly is now accessible to a wide range of researchers. It is therefore necessary to understand the best methods for genera...

    Authors: Jason G Powers, Victor J Weigman, Jenny Shu, John M Pufky, Donald Cox and Patrick Hurban
    Citation: BMC Genomics 2013 14:675
    Content type: Methodology article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 3.5
    5-year Journal Impact Factor: 4.1
    Source Normalized Impact per Paper (SNIP): 1.083
    SCImago Journal Rank (SJR): 1.047

    Speed 2023
    Submission to first editorial decision (median days): 21
    Submission to acceptance (median days): 137

    Usage 2023
    Downloads: 7,167,242
    Altmetric mentions: 4,454

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us