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6355 result(s) for 'general transcription factors vs specific' within BMC Genomics

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  1. Systemic administration of β-adrenoceptor (β-AR) agonists has been found to induce skeletal muscle hypertrophy and significant metabolic changes. In the context of energy homeostasis, the importance of β-AR si...

    Authors: Michael A Pearen, James G Ryall, Gordon S Lynch and George EO Muscat
    Citation: BMC Genomics 2009 10:448
    Content type: Research article Published on:

  2. Long non-coding RNAs (lncRNAs) are involved in several immune processes, including the immune response to vaccination, but most of them remain uncharacterised in livestock species. The mechanism of action of a...

    Authors: Martin Bilbao-Arribas, Endika Varela-Martínez, Naiara Abendaño, Damián de Andrés, Lluís Luján and Begoña M. Jugo
    Citation: BMC Genomics 2021 22:770
    Content type: Research Published on:

  3. Previous studies show that galanin neurons in ventrolateral preoptic nucleus (VLPO-Gal) are essential for sleep regulation. Here, we explored the transcriptional regulation of the VLPO-Gal neurons in sleep by ...

    Authors: Xiaofeng Guo, Xiaoling Gao, Brendan T. Keenan, Jingxu Zhu, Dimitra Sarantopoulou, Jie Lian, Raymond J. Galante, Gregory R. Grant and Allan I. Pack
    Citation: BMC Genomics 2020 21:633
    Content type: Research article Published on:

  4. CRISPR/Cas9-mediated transcriptional interference (CRISPRi) enables programmable gene knock-down, yielding loss-of-function phenotypes for nearly any gene. Effective, inducible CRISPRi has been demonstrated in...

    Authors: Nicholas J. McGlincy, Zuriah A. Meacham, Kendra K. Reynaud, Ryan Muller, Rachel Baum and Nicholas T. Ingolia
    Citation: BMC Genomics 2021 22:205
    Content type: Methodology article Published on:

  5. Bean pyralid is one of the major leaf-feeding insects that affect soybean crops. DNA methylation can control the networks of gene expressions, and it plays an important role in responses to biotic stress. Howe...

    Authors: Wei-Ying Zeng, Yu-Rong Tan, Sheng-Feng Long, Zu-Dong Sun, Zhen-Guang Lai, Shou-Zhen Yang, Huai-Zhu Chen and Xia-Yan Qing
    Citation: BMC Genomics 2021 22:836
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2021 22:913

  6. The SROs (SIMILAR TO RCD-ONE) are a group of plant-specific proteins which have important functions in stress adaptation and development. They contain the catalytic core of the poly(ADP-ribose) polymerase (PAR...

    Authors: Pinja Jaspers, Kirk Overmyer, Michael Wrzaczek, Julia P Vainonen, Tiina Blomster, Jarkko Salojärvi, Ramesha A Reddy and Jaakko Kangasjärvi
    Citation: BMC Genomics 2010 11:170
    Content type: Research article Published on:

  7. Regulation of gene expression plays important role in cellular functions. Co-regulation of different genes may indicate functional connection or even physical interaction between gene products. Thus analysis o...

    Authors: Wanling Yang, Ping Ng, Minghui Zhao, Thomas KF Wong, Siu-Ming Yiu and Yu Lung Lau
    Citation: BMC Genomics 2008 9:456
    Content type: Research article Published on:

  8. The surface of the human eye is covered by corneal epithelial cells (CECs) which regenerate from a small population of limbal epithelial stem cells (LESCs). Cell therapy with LESCs is a non-penetrating treatme...

    Authors: Zoltán Veréb, Réka Albert, Szilárd Póliska, Ole Kristoffer Olstad, Saeed Akhtar, Morten C Moe and Goran Petrovski
    Citation: BMC Genomics 2013 14:900
    Content type: Research article Published on:

  9. Five-needle pines are important forest species that have been devastated by white pine blister rust (WPBR, caused by Cronartium ribicola) across North America. Currently little transcriptomic and genomic data are...

    Authors: Jun-Jun Liu, Rona N Sturrock and Ross Benton
    Citation: BMC Genomics 2013 14:884
    Content type: Research article Published on:

  10. MicroRNAs are non-coding RNAs that regulate gene expression including differentiation and development by either inhibiting translation or inducing target degradation. The aim of this study is to determine the ...

    Authors: Samuel Rosero, Valia Bravo-Egana, Zhijie Jiang, Sawsan Khuri, Nicholas Tsinoremas, Dagmar Klein, Eduardo Sabates, Mayrin Correa-Medina, Camillo Ricordi, Juan Domínguez-Bendala, Juan Diez and Ricardo L Pastori
    Citation: BMC Genomics 2010 11:509
    Content type: Research article Published on:

  11. Germ cells must progress through elaborate developmental stages from an undifferentiated germ cell to a fully differentiated gamete. Some of these stages include exiting mitosis and entering meiosis, progressi...

    Authors: Xin Wang, Yongjun Zhao, Kim Wong, Peter Ehlers, Yuji Kohara, Steven J Jones, Marco A Marra, Robert A Holt, Donald G Moerman and Dave Hansen
    Citation: BMC Genomics 2009 10:213
    Content type: Research article Published on:

  12. Globoid cell leukodystrophy (GLD) is a devastating neurodegenerative disease characterized by widespread demyelination caused by galactocerebrosidase defects. Changes in GLD pathogenesis occurring at the molec...

    Authors: Yafeng Lv, Yu Qin, Jing Wang, Guoshuai Tian, Wei Wang, Chunyu Cao and Ye Zhang
    Citation: BMC Genomics 2023 24:210
    Content type: Research Published on:

  13. In the genome of Caenorhabditis elegans, homopolymeric poly-G/poly-C tracts (G/C tracts) exist at high frequency and are maintained by the activity of the DOG-1 protein. The frequency and distribution of G/C trac...

    Authors: Yang Zhao, Nigel J O'Neil and Ann M Rose
    Citation: BMC Genomics 2007 8:403
    Content type: Research article Published on:

  14. Emissions from diesel vehicles and biomass burning are the principal sources of primary ultrafine particles (UFP). The exposure to UFP has been associated to cardiovascular and pulmonary diseases, including lu...

    Authors: Andrea Grilli, Rossella Bengalli, Eleonora Longhin, Laura Capasso, Maria Carla Proverbio, Mattia Forcato, Silvio Bicciato, Maurizio Gualtieri, Cristina Battaglia and Marina Camatini
    Citation: BMC Genomics 2018 19:302
    Content type: Research article Published on:

  15. Adipogenesis is the developmental process by which mesenchymal stem cells (MSC) differentiate into pre-adipocytes and adipocytes. The aim of the study was to analyze the developmental strategies of human bone ...

    Authors: Adriane Menssen, Thomas Häupl, Michael Sittinger, Bruno Delorme, Pierre Charbord and Jochen Ringe
    Citation: BMC Genomics 2011 12:461
    Content type: Research article Published on:

  16. Despite proven therapeutic effects in inflammatory conditions, the specific mechanisms of phytochemical therapies are not well understood. The transcriptome effects of Traumeel (Tr14), a multicomponent natural...

    Authors: Georges St. Laurent III, Ian Toma, Bernd Seilheimer, Konstantin Cesnulevicius, Myron Schultz, Michael Tackett, Jianhua Zhou, Maxim Ri, Dmitry Shtokalo, Denis Antonets, Tisha Jepson and Timothy A. McCaffrey
    Citation: BMC Genomics 2021 22:854
    Content type: Research Published on:

  17. The genus Bothrops is widespread throughout Central and South America and is the principal cause of snakebite in these regions. Transcriptomic and proteomic studies have examined the venom composition of several ...

    Authors: Kiara C Cardoso, Márcio J Da Silva, Gustavo GL Costa, Tatiana T Torres, Luiz Eduardo V Del Bem, Ramon O Vidal, Marcelo Menossi and Stephen Hyslop
    Citation: BMC Genomics 2010 11:605
    Content type: Research article Published on:

  18. DNA methylation is a heritable mechanism that acts in response to environmental changes, lifestyle and diseases by influencing gene expression in eukaryotes. Epigenetic studies of wild organisms are mandatory ...

    Authors: Alexandra Weyrich, Tino Schüllermann, Felix Heeger, Marie Jeschek, Camila J Mazzoni, Wei Chen, Kathrin Schumann and Joerns Fickel
    Citation: BMC Genomics 2014 15:1036
    Content type: Methodology article Published on:

  19. Seeds are the economic basis of oilseed crops, especially soybeans, the most widely cultivated oilseed crop worldwide. Seed development is accompanied by a multitude of diverse cellular processes, and revealin...

    Authors: Hengyou Zhang, Zhenbin Hu, Yuming Yang, Xiaoqian Liu, Haiyan Lv, Bao-Hua Song, Yong-qiang Charles An, Zhimin Li and Dan Zhang
    Citation: BMC Genomics 2021 22:453
    Content type: Research article Published on:

  20. Cancer cells frequently adopt cellular and molecular alterations and acquire resistance to cytostatic drugs. Chemotherapy with oxaliplatin is among the leading treatments for colorectal cancer with a response ...

    Authors: Piroska Virag, Eva Fischer-Fodor, Maria Perde-Schrepler, Ioana Brie, Corina Tatomir, Loredana Balacescu, Ioana Berindan-Neagoe, Bogdan Victor and Ovidiu Balacescu
    Citation: BMC Genomics 2013 14:480
    Content type: Research article Published on:

  21. Sessile bivalves of the genus Mytilus are suspension feeders relatively tolerant to a wide range of environmental changes, used as sentinels in ecotoxicological investigations and marketed worldwide as seafood. M...

    Authors: Paola Venier, Laura Varotto, Umberto Rosani, Caterina Millino, Barbara Celegato, Filippo Bernante, Gerolamo Lanfranchi, Beatriz Novoa, Philippe Roch, Antonio Figueras and Alberto Pallavicini
    Citation: BMC Genomics 2011 12:69
    Content type: Research article Published on:

  22. Small non-coding RNAs (sRNAs) have attracted attention as a new class of gene regulators in both eukaryotes and bacteria. Genome-wide screening methods have been successfully applied in Gram-negative bacteria ...

    Authors: Nadja Patenge, André Billion, Peter Raasch, Jana Normann, Aleksandra Wisniewska-Kucper, Julia Retey, Valesca Boisguérin, Thomas Hartsch, Torsten Hain and Bernd Kreikemeyer
    Citation: BMC Genomics 2012 13:550
    Content type: Research article Published on:

  24. Transcription has a substantial genetic control and genetic dissection of gene expression could help us understand the genetic architecture of complex phenotypes such as meat quality in cattle. The objectives ...

    Authors: Joel D. Leal-Gutiérrez, Mauricio A. Elzo and Raluca G. Mateescu
    Citation: BMC Genomics 2020 21:104
    Content type: Research article Published on:

  25. Udder infections with environmental pathogens like Escherichia coli are a serious problem for the dairy industry. Reduction of incidence and severity of mastitis is desirable and mild priming of the immune system...

    Authors: Juliane Günther, Wolfram Petzl, Holm Zerbe, Hans-Joachim Schuberth, Dirk Koczan, Leopold Goetze and Hans-Martin Seyfert
    Citation: BMC Genomics 2012 13:17
    Content type: Research article Published on:

  26. Nyctotherus ovalis is a single-celled eukaryote that has hydrogen-producing mitochondria and lives in the hindgut of cockroaches. Like all members of the ciliate taxon, it has two types of nuclei, a micronucleus ...

    Authors: Guénola Ricard, Rob M de Graaf, Bas E Dutilh, I Duarte, Theo A van Alen, Angela HAM van Hoek, Brigitte Boxma, Georg WM van der Staay, Seung Yeo Moon-van der Staay, Wei-Jen Chang, Laura F Landweber, Johannes HP Hackstein and Martijn A Huynen
    Citation: BMC Genomics 2008 9:587
    Content type: Research article Published on:

  27. Drought and soil salinity are major abiotic stresses. The mechanisms of stress tolerance have been studied extensively in model plants. Caragana korshinskii is characterized by high drought and salt tolerance in ...

    Authors: Shaofeng Li, Chengming Fan, Yan Li, Jianhui Zhang, Jingshuang Sun, Yuhong Chen, Changyan Tian, Xiaohua Su, Mengzhu Lu, Chengzhi Liang and Zanmin Hu
    Citation: BMC Genomics 2016 17:200
    Content type: Research article Published on:

  28. Carolacton is a newly identified secondary metabolite causing altered cell morphology and death of Streptococcus mutans biofilm cells. To unravel key regulators mediating these effects, the transcriptional regula...

    Authors: Padhmanand Sudhakar, Michael Reck, Wei Wang, Feng Q He, Irene W Dobler and An-Ping Zeng
    Citation: BMC Genomics 2014 15:362
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2014 15:739

  29. Cellular differentiation programs are controlled, to a large extent, by the combinatorial functioning of specific transcription factors. Cortical projection neurons constitute the major excitatory neuron popul...

    Authors: Efil Bayam, Gulcan Semra Sahin, Gizem Guzelsoy, Gokhan Guner, Alkan Kabakcioglu and Gulayse Ince-Dunn
    Citation: BMC Genomics 2015 16:681
    Content type: Research article Published on:

  30. With only 2 % of the human genome consisting of protein coding genes, functionality across the rest of the genome has been the subject of much debate. This has gained further impetus in recent years due to a r...

    Authors: Thijessen Naidoo, Per Sjödin, Carina Schlebusch and Mattias Jakobsson
    Citation: BMC Genomics 2018 19:95
    Content type: Research article Published on:

  31. The discovery of male sterile materials is of great significance for the development of plant fertility research. Wucai (Brassica campestris L. ssp. chinensis var. rosularis Tsen) is a variety of non-heading Chin...

    Authors: Jian Wang, Yitao Yang, Lei Zhang, Shaoxing Wang, Lingyun Yuan, Guohu Chen, Xiaoyan Tang, Jinfeng Hou, Shidong Zhu and Chenggang Wang
    Citation: BMC Genomics 2021 22:654
    Content type: Research Published on:

  32. The Zap1 transcription factor is a central player in the response of yeast to changes in zinc status. We previously used transcriptome profiling with DNA microarrays to identify 46 potential Zap1 target genes ...

    Authors: Chang-Yi Wu, Amanda J Bird, Lisa M Chung, Michael A Newton, Dennis R Winge and David J Eide
    Citation: BMC Genomics 2008 9:370
    Content type: Research article Published on:

  33. One of the great advantages of next generation sequencing is the ability to generate large genomic datasets for virtually all species, including non-model organisms. It should be possible, in turn, to apply ad...

    Authors: Lijun Liu, Victor Missirian, Matthew Zinkgraf, Andrew Groover and Vladimir Filkov
    Citation: BMC Genomics 2014 15(Suppl 5):S3
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 5

  34. Chickpea, pigeonpea, and groundnut are the primary legume crops of semi-arid tropics (SAT) and their global productivity is severely affected by drought stress. The plant-specific NAC (NAM - no apical meristem...

    Authors: Sadhana Singh, Himabindu Kudapa, Vanika Garg and Rajeev K. Varshney
    Citation: BMC Genomics 2021 22:289
    Content type: Research article Published on:

  35. Lung maturation is a late fetal developmental event in both mice and humans. Because of this, lung immaturity is a serious problem in premature infants. Disruption of genes for either the glucocorticoid recept...

    Authors: Mathieu Lajoie, Yu-Chih Hsu, Richard M Gronostajski and Timothy L Bailey
    Citation: BMC Genomics 2014 15:231
    Content type: Research article Published on:

  36. The stress response in bacteria involves the multistage control of gene expression but is not entirely understood. To identify the translational response of bacteria in stress conditions and assess its contrib...

    Authors: Flora Picard, Pascal Loubière, Laurence Girbal and Muriel Cocaign-Bousquet
    Citation: BMC Genomics 2013 14:588
    Content type: Research article Published on:

  37. Nuclear receptors have crucial roles in all metazoan animals as regulators of gene transcription. A wide range of studies have elucidated molecular and biological significance of nuclear receptors but there ar...

    Authors: Christiane Eichner, Sussie Dalvin, Rasmus Skern-Mauritzen, Ketil Malde, Heidi Kongshaug and Frank Nilsen
    Citation: BMC Genomics 2015 16:81
    Content type: Research article Published on:

  38. Bovine viral diarrhoea virus (BVDV) is the member of the genus Pestivirus within the Flaviviridae family and responsible for severe economic losses in the cattle industry. BVDV can employ ‘infect-and-persist’ str...

    Authors: Cun Liu, Yanhan Liu, Lin Liang, Shangjin Cui and Yanming Zhang
    Citation: BMC Genomics 2019 20:774
    Content type: Research article Published on:

  39. Sterile and fertile flowers are important evolutionary developmental phenotypes in angiosperm flowers. The development of floral organs, critical in angiosperm reproduction, is regulated by microRNAs (miRNAs)....

    Authors: Weixing Li, Zhichong He, Li Zhang, Zhaogeng Lu, Jing Xu, Jiawen Cui, Li Wang and Biao Jin
    Citation: BMC Genomics 2017 18:783
    Content type: Research article Published on:

  40. Plants grown under shade are exposed to low red/far-red ratio, thereby triggering an array of altered phenotypes called shade avoidance syndrome (SAS). Shade negatively influences plant growth, leading to a re...

    Authors: Nguyen Hoai Nguyen, Benny Jian Rong Sng, Hock Chuan Yeo and In-Cheol Jang
    Citation: BMC Genomics 2021 22:760
    Content type: Research Published on:

  42. Colletotrichum graminicola is a hemibiotrophic fungal pathogen that causes maize anthracnose disease. It progresses through three recognizable phases of pathogenic development in plant...

    Authors: Maria F. Torres, Noushin Ghaffari, Ester A. S. Buiate, Neil Moore, Scott Schwartz, Charles D. Johnson and Lisa J. Vaillancourt
    Citation: BMC Genomics 2016 17:202
    Content type: Research article Published on:

  43. T-cell activation is an essential step of the immune response and relies on the tightly controlled orchestration of hundreds of genes/proteins, yet the cellular and molecular events underlying this complex pro...

    Authors: Min Wang, Dirk Windgassen and Eleftherios T Papoutsakis
    Citation: BMC Genomics 2008 9:225
    Content type: Research article Published on:

  44. The tropical ascomycete Trichoderma reesei (Hypocrea jecorina) represents one of the most efficient plant cell wall degraders. Regulation of the enzymes required for this process is affected by nutritional signal...

    Authors: Doris Tisch and Monika Schmoll
    Citation: BMC Genomics 2013 14:657
    Content type: Research article Published on:

  45. MicroRNAs (miRNAs) modulate gene expression in different tissues and at diverse developmental stages, including grain development in japonica rice. To identify novel miRNAs in indica rice and to study their ex...

    Authors: Ying Lan, Ning Su, Yi Shen, Rongzhi Zhang, Fuqing Wu, Zhijun Cheng, Jiulin Wang, Xin Zhang, Xiupin Guo, Cailin Lei, Jie Wang, Ling Jiang, Long Mao and Jianmin Wan
    Citation: BMC Genomics 2012 13:264
    Content type: Research article Published on:

  46. A single Glycine max (soybean) genotype (Peking) reacts differently to two different populations of Heterodera glycines (soybean cyst nematode) within the first twelve hours of infection during resistant (R) and ...

    Authors: Vincent P Klink, Parsa Hosseini, Margaret H MacDonald, Nadim W Alkharouf and Benjamin F Matthews
    Citation: BMC Genomics 2009 10:111
    Content type: Research article Published on:

  47. The events leading to sepsis start with an invasive infection of a primary organ of the body followed by an overwhelming systemic response. Intra-abdominal infections are the second most common cause of sepsis...

    Authors: Minny Bhatty, Ruping Fan, William M Muir, Stephen B Pruett and Bindu Nanduri
    Citation: BMC Genomics 2012 13:509
    Content type: Research article Published on:

  48. The amplification of bacterial RNA is required if complex host-pathogen interactions are to be studied where the recovery of bacterial RNA is limited. Here, using a whole genome Mycobacterium tuberculosis microar...

    Authors: Simon J Waddell, Ken Laing, Claire Senner and Philip D Butcher
    Citation: BMC Genomics 2008 9:94
    Content type: Methodology article Published on:

  49. Early stages of fruit development from initial set through exponential growth are critical determinants of size and yield, however, there has been little detailed analysis of this phase of development. In this...

    Authors: Kaori Ando, Kevin M Carr and Rebecca Grumet
    Citation: BMC Genomics 2012 13:518
    Content type: Research article Published on:

  50. Lepeophtheirus salmonis is an ectoparasitic copepod feeding on skin, mucus and blood from salmonid hosts. Initial analysis of EST sequences from pre adult and adult stages of L. salmonis revealed a large proporti...

    Authors: Christiane Eichner, Petter Frost, Bjarte Dysvik, Inge Jonassen, Bjørn Kristiansen and Frank Nilsen
    Citation: BMC Genomics 2008 9:126
    Content type: Research article Published on:

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