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  1. Marine deep subsurface sediments were once thought to be devoid of eukaryotic life, but advances in molecular technology have unlocked the presence and activity of well-known closely related terrestrial and ma...

    Authors: Morgan S. Sobol, Tatsuhiko Hoshino, Victor Delgado, Taiki Futagami, Chihiro Kadooka, Fumio Inagaki and Brandi Kiel Reese
    Citation: BMC Genomics 2023 24:249
    Content type: Research Published on:

  2. The Human Leukocyte Antigen (HLA) genes are a group of highly polymorphic genes that are located in the Major Histocompatibility Complex (MHC) region on chromosome 6. The HLA genotype affects the presentabilit...

    Authors: Arne Claeys, Peter Merseburger, Jasper Staut, Kathleen Marchal and Jimmy Van den Eynden
    Citation: BMC Genomics 2023 24:247
    Content type: Research Published on:

  4. Semen cryopreservation is a critical tool for breed improvement and preservation of biodiversity. However, instability of sperm freezability affects its application. The Mediterranean buffalo is one of the riv...

    Authors: Xi Luo, Mingming Liang, Shihai Huang, Qingsong Xue, Xuan Ren, Yanfang Li, Jinli Wang, Deshun Shi and Xiangping Li
    Citation: BMC Genomics 2023 24:245
    Content type: Research Published on:

  6. Sex determination is the process whereby the bipotential embryonic gonads become committed to differentiate into testes or ovaries. In genetic sex determination (GSD), the sex determining trigger is encoded by...

    Authors: Susan Wagner, Sarah L. Whiteley, Meghan Castelli, Hardip R. Patel, Ira W. Deveson, James Blackburn, Clare E. Holleley, Jennifer A. Marshall Graves and Arthur Georges
    Citation: BMC Genomics 2023 24:243
    Content type: Research Published on:

  8. Lineage distribution of Mycobacterium tuberculosis (Mtb) isolates is strongly associated with geographically distinct human populations, and its transmission can be further impacted by the bacterial genome. Howev...

    Authors: Zonglei Zhou, Huaiming Yi, Qingrong Zhou, Luqi Wang, Yue Zhu, Weibing Wang, Zhengwe Liu and Haiyan Xiong
    Citation: BMC Genomics 2023 24:241
    Content type: Research Published on:

  9. Alternative splicing is an important step in gene expression, generating multiple isoforms for the same genes and greatly expanding the diversity of proteomes. Genetic variation in alternative splicing contrib...

    Authors: Fei Zhang, Deborah Velez-Irizarry, Catherine W. Ernst and Wen Huang
    Citation: BMC Genomics 2023 24:240
    Content type: Research Published on:

  10. N6-methyladenosine (m6A) refers to the methylation modification of N6 position of RNA adenine, a dynamic reversible RNA epigenetic modification that plays an important regulatory role in a variety of life process...

    Authors: Yaqing Dou, Yilin Wei, Zhe Zhang, Chenlei Li, Chenglei Song, Yingke Liu, Kunlong Qi, Xinjian Li, Xiuling Li, Ruimin Qiao, Kejun Wang, Feng Yang and Xuelei Han
    Citation: BMC Genomics 2023 24:239
    Content type: Research Published on:

  12. Microsporidia are diverse spore forming, fungal-related obligate intracellular pathogens infecting a wide range of hosts. This diversity is reflected at the genome level with sizes varying by an order of magni...

    Authors: Anne Caroline Mascarenhas dos Santos, Alexander Thomas Julian, Pingdong Liang, Oscar Juárez and Jean-François Pombert
    Citation: BMC Genomics 2023 24:237
    Content type: Research Published on:

  13. Plant sexual reproduction is highly sensitive to elevated ambient temperatures, impacting seed development and production. We previously phenotyped this effect on three rapeseed cultivars (DH12075, Topas DH407...

    Authors: Veronika Jedličková, Václav Hejret, Martin Demko, Pavel Jedlička, Marie Štefková and Hélène S. Robert
    Citation: BMC Genomics 2023 24:236
    Content type: Research Published on:

  14. DNA hypermethylation at promoter CpG islands (CGIs) is a hallmark of cancers and could lead to dysregulation of gene expression in the development of cancers, however, its dynamics and regulatory mechanisms r...

    Authors: Yang Lu, Qiang Cao, Yue Yu, Yazhou Sun, Xuan Jiang and Xin Li
    Citation: BMC Genomics 2023 24:235
    Content type: Research Published on:

  15. Understanding the genetic mechanisms underlying coat color inheritance has always been intriguing irrespective of the animal species including American mink (Neogale vison). The study of color inheritance in Amer...

    Authors: Persia Carol Thapa, Duy Ngoc Do, Ghader Manafiazar and Younes Miar
    Citation: BMC Genomics 2023 24:234
    Content type: Research Published on:

  17. The purpose of this study is to investigate the association of rotating night shift work, CLOCK, MTNR1A, MTNR1B genes polymorphisms and their interactions with type 2 diabetes among steelworkers.

    Authors: Qinglin Li, Shengkui Zhang, Han Wang, Zhende Wang, Xiaohong Zhang, Yongbin Wang and Juxiang Yuan
    Citation: BMC Genomics 2023 24:232
    Content type: Research Published on:

  18. Scale insects are worldwide sap-sucking parasites, which can be distinguished into neococcoids and non-neococcoids. Neococcoids are monophyletic with a peculiar reproductive system, paternal genome elimination...

    Authors: Xue-Fei Tang, Yu-Hao Huang, Yi-Fei Sun, Pei-Fang Zhang, Li-Zhi Huo, Hao-Sen Li and Hong Pang
    Citation: BMC Genomics 2023 24:231
    Content type: Research Published on:

  19. The reduction in phenotypic performance of a population due to mating between close relatives is called inbreeding depression. The genetic background of inbreeding depression for semen traits is poorly underst...

    Authors: Mohammad Ghoreishifar, Seyed Milad Vahedi, Siavash Salek Ardestani, Majid Khansefid and Jennie E. Pryce
    Citation: BMC Genomics 2023 24:230
    Content type: Research Published on:

  20. Mitochondrial genome sequences have become critical to the study of biodiversity. Genome skimming and other short-read based methods are the most common approaches, but they are not well-suited to scale up to ...

    Authors: Benjamin R. Karin, Selene Arellano, Laura Wang, Kayla Walzer, Aaron Pomerantz, Juan Manuel Vasquez, Kamalakar Chatla, Peter H. Sudmant, Bryan H. Bach, Lydia L. Smith and Jimmy A. McGuire
    Citation: BMC Genomics 2023 24:229
    Content type: Research article Published on:

  21. Single-cell RNA sequencing is a state-of-the-art technology to understand gene expression in complex tissues. With the growing amount of data being generated, the standardization and automation of data analysi...

    Authors: Kejie Li, Yu H. Sun, Zhengyu Ouyang, Soumya Negi, Zhen Gao, Jing Zhu, Wanli Wang, Yirui Chen, Sarbottam Piya, Wenxing Hu, Maria I. Zavodszky, Hima Yalamanchili, Shaolong Cao, Andrew Gehrke, Mark Sheehan, Dann Huh…
    Citation: BMC Genomics 2023 24:228
    Content type: Software Published on:

  22. It is now possible to analyze cellular heterogeneity at the single-cell level thanks to the rapid developments in single-cell sequencing technologies. The clustering of cells is a fundamental and common step i...

    Authors: Saeedeh Akbari Rokn Abadi, Seyed Pouria Laghaee and Somayyeh Koohi
    Citation: BMC Genomics 2023 24:227
    Content type: Research Published on:

  24. Structural variants (SVs) are chromosomal segments that differ between genomes, such as deletions, duplications, insertions, inversions and translocations. The genomics revolution enabled the discovery of sub-...

    Authors: Young-Lim Lee, Mirte Bosse, Haruko Takeda, Gabriel Costa Monteiro Moreira, Latifa Karim, Tom Druet, Claire Oget-Ebrad, Wouter Coppieters, Roel F. Veerkamp, Martien A. M. Groenen, Michel Georges, Aniek C. Bouwman and Carole Charlier
    Citation: BMC Genomics 2023 24:225
    Content type: Research Published on:

  25. The receptor-like kinase (RLK) gene families in plants contains a large number of members. They are membrane proteins with an extracellular receptor domain and participate in biotic and abiotic stress responses.

    Authors: Jun Yan, Peisen Su, Xianyong Meng and Pingzeng Liu
    Citation: BMC Genomics 2023 24:224
    Content type: Research Published on:

  26. Eucalyptus urophylla × Eucalyptus grandis, an economically important forest tree, provides important raw material for energy and reduces damage to native forests. However, the absence of a high-quality E. urophyl...

    Authors: Chao Shen, Limei Li, Lejun Ouyang, Min Su and Kexin Guo
    Citation: BMC Genomics 2023 24:223
    Content type: Research Published on:

  27. The Rhus gall aphid Schlechtendalia chinensis specially uses the only species Rhus chinensis and certain moss species (Mniaceae) as its primary host plant and secondary host plants, respectively. Rhus galls are f...

    Authors: Hongli He, M. James C. Crabbe and Zhumei Ren
    Citation: BMC Genomics 2023 24:222
    Content type: Research Published on:

  28. Head and neck squamous cell carcinoma (HNSCC) are the most common cancers in the head and neck. Therapeutic response-related genes (TRRGs) are closely associated with carcinogenesis and prognosis in HNSCC. How...

    Authors: Cheng Lin, Yuebing Chen, Jianji Pan, Qiongjiao Lu, Pengjie Ji, Shuiqin Lin, Chunfeng Liu, Shaojun Lin, Meifang Li and Jingfeng Zong
    Citation: BMC Genomics 2023 24:221
    Content type: Research Published on:

  30. The plant cysteine-rich receptor-like kinases (CRKs) are a large family having multiple roles, including defense responses under both biotic and abiotic stress. However, the CRK family in cucumbers (Cucumis sativ...

    Authors: Satyabrata Nanda, Priyadarshini Rout, Ikram Ullah, Swapna Rani Nag, Velagala Veerraghava Reddy, Gagan Kumar, Ritesh Kumar, Shuilian He and Hongzhi Wu
    Citation: BMC Genomics 2023 24:219
    Content type: Research Published on:

  31. Bacillomycin D-C16 can induce resistance in cherry tomato against pathogens; however, the underlying molecular mechanism is poorly understood. Here, the effect of Bacillomycin D-C16 on induction of disease res...

    Authors: Yingying Xue, Jing Sun, Fengxia Lu, Xiaomei Bie, Yuanhong Li, Yingjian Lu, Zhaoxin Lu and Fuxing Lin
    Citation: BMC Genomics 2023 24:218
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:451

  32. Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers. Long non-coding RNAs (lncRNAs) can regulate gene expression and contribute t...

    Authors: Chenxi Zhang, Ying Zhou, Bin Zhang, Zhihong Sheng, Nan Sun, Baiyin Yuan and Xiaoyuan Wu
    Citation: BMC Genomics 2023 24:217
    Content type: Research Published on:

  33. Major depressive disorder (MDD) is a life-threatening and debilitating mental health condition. Mitophagy, a form of selective autophagy that eliminates dysfunctional mitochondria, is associated with depressio...

    Authors: Jing Zhang, Shujun Xie, Rong Xiao, Dongrong Yang, Zhi Zhan and Yan Li
    Citation: BMC Genomics 2023 24:216
    Content type: Research Published on:

  34. Cancer is a life-threatening disease in humans; yet, cancer genes are frequently reported to be under positive selection. This suggests an evolutionary-genetic paradox in which cancer evolves as a secondary pr...

    Authors: Langyu Gu, Canwei Xia, Shiyu Yang and Guofen Yang
    Citation: BMC Genomics 2023 24:215
    Content type: Research Published on:

  35. Salmonella enterica serovar typhimurium is the cause of significant morbidity and mortality worldwide that causes economic losses to poultry and is able to cause infection in humans. Indigenous chicken breeds are...

    Authors: Syed Mudasir Ahmad, Sahar Saleem Bhat, Shaista Shafi, Mashooq Ahmad Dar, Afnan Saleem, Zulfqarul Haq, Nida Farooq, Junaid Nazir and Basharat Bhat
    Citation: BMC Genomics 2023 24:214
    Content type: Research Published on:

  36. Understanding the mechanisms underlining forage production and its biomass nutritive quality at the omics level is crucial for boosting the output of high-quality dry matter per unit of land. Despite the adven...

    Authors: Elesandro Bornhofen, Dario Fè, Istvan Nagy, Ingo Lenk, Morten Greve, Thomas Didion, Christian S. Jensen, Torben Asp and Luc Janss
    Citation: BMC Genomics 2023 24:213
    Content type: Research Published on:

  37. Early-onset renal cell carcinoma (eoRCC) is typically associated with pathogenic germline variants (PGVs) in RCC familial syndrome genes. However, most eoRCC patients lack PGVs in familial RCC genes and their gen...

    Authors: Elena V. Demidova, Ilya G. Serebriiskii, Ramilia Vlasenkova, Simon Kelow, Mark D. Andrake, Tiffiney R. Hartman, Tatiana Kent, James Virtucio, Gail L. Rosen, Richard T. Pomerantz, Roland L. Dunbrack Jr., Erica A. Golemis, Michael J. Hall, David Y. T. Chen, Mary B. Daly and Sanjeevani Arora
    Citation: BMC Genomics 2023 24:212
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:388

  38. Diarrhea is one of the most common diseases in pig industry, which seriously threatens the health of piglets and causes huge economic losses. Enterotoxigenic Escherichia coli (ETEC) F4 is regarded as the most ...

    Authors: Qingyao Zhao, Qinglei Xu, MA. Serafino, Qin Zhang, Chuduan Wang and Ying Yu
    Citation: BMC Genomics 2023 24:211
    Content type: Research Published on:

  39. Globoid cell leukodystrophy (GLD) is a devastating neurodegenerative disease characterized by widespread demyelination caused by galactocerebrosidase defects. Changes in GLD pathogenesis occurring at the molec...

    Authors: Yafeng Lv, Yu Qin, Jing Wang, Guoshuai Tian, Wei Wang, Chunyu Cao and Ye Zhang
    Citation: BMC Genomics 2023 24:210
    Content type: Research Published on:

  40. Sulfate-reducing bacteria (SRB) drive the ocean sulfur and carbon cycling. They constitute a diverse phylogenetic and physiological group and are widely distributed in anoxic marine environments. From a physio...

    Authors: Ping Gao, Xiaoting Zhang, Xiaomei Huang, Zhiyi Chen, Angeliki Marietou, Lars Holmkvist, Lingyun Qu, Kai Finster and Xianzhe Gong
    Citation: BMC Genomics 2023 24:209
    Content type: Research article Published on:

  41. De novo mutations arising in the germline are a source of genetic variation and their discovery broadens our understanding of genetic disorders and evolutionary patterns. Although the number of de novo single nuc...

    Authors: Marije J. Steensma, Y. L. Lee, A. C. Bouwman, C. Pita Barros, M. F.L. Derks, M. C.A.M. Bink, B. Harlizius, A. E. Huisman, R. P.M.A. Crooijmans, M. A.M. Groenen, H. A. Mulder and C. M. Rochus
    Citation: BMC Genomics 2023 24:208
    Content type: Research Published on:

  42. Monocytes -key regulators of the innate immune response- are actively involved in the pathogenesis of systemic lupus erythematosus (SLE). We sought to identify novel compounds that might serve as monocyte-dire...

    Authors: Dimitrios Nikolakis, Panagiotis Garantziotis, George Sentis, Antonis Fanouriakis, George Bertsias, Eleni Frangou, Dionysis Nikolopoulos, Aggelos Banos and Dimitrios T Boumpas
    Citation: BMC Genomics 2023 24:207
    Content type: Research Published on:

  43. Inherited retinal diseases (IRD) are genetically heterogeneous disorders that cause the dysfunction or loss of photoreceptor cells and ultimately lead to blindness. To date, next-generation sequencing procedur...

    Authors: Karla Alejandra Ruiz-Ceja, Dalila Capasso, Michele Pinelli, Eugenio Del Prete, Diego Carrella, Diego di Bernardo and Sandro Banfi
    Citation: BMC Genomics 2023 24:206
    Content type: Research Published on:

  44. RNA sequencing has become the mainstay for studies of gene expression. Still, analysis of rare cells with random hexamer priming – to allow analysis of a broader range of transcripts – remains challenging.

    Authors: Charlotte Gustafsson, Julia Hauenstein, Nicolai Frengen, Aleksandra Krstic, Sidinh Luc and Robert Månsson
    Citation: BMC Genomics 2023 24:205
    Content type: Research Published on:

  45. Jute is considered one of the most important crops for fiber production and multipurpose usages. Caffeoyl-CoA 3-O-methyltransferase (CCoAOMT) is a crucial enzyme involved in lignin biosynthesis in plants. The pot...

    Authors: Mohamed Ali Kahie, Yongjun Wang, Pingping Fang, Jianmin Qi, Rongjie Lei, Jiantang Xu, Lihui Lin, Liwu Zhang, Jisen Zhang and Aifen Tao
    Citation: BMC Genomics 2023 24:204
    Content type: Research Published on:

  46. The freshwater leech Whitmania pigra (W. pigra) Whitman (Annelida phylum) is a model organism for neurodevelopmental studies. However, molecular biology research on its embryonic development is still scarce. Here...

    Authors: Jiali Liu, Jinxin Liu, Mingyue Li, Lisi Zhou, Weijun Kong, Hailin Zhang, Panpan Jin, Fuhua Lu, Gufa Lin and Linchun Shi
    Citation: BMC Genomics 2023 24:203
    Content type: Research Published on:

  47. High throughput sequencing has enabled the interrogation of the transcriptomic landscape of glucagon-secreting alpha cells, insulin-secreting beta cells, and somatostatin-secreting delta cells. These approache...

    Authors: Alex M. Mawla, Talitha van der Meulen and Mark O. Huising
    Citation: BMC Genomics 2023 24:202
    Content type: Research Published on:

  48. Nucleosome remodeling factors regulate the occupancy and positioning of nucleosomes genome-wide through ATP-driven DNA translocation. While many nucleosomes are consistently well-positioned, some nucleosomes a...

    Authors: David C. Klein, Kris Troy, Sarah A. Tripplehorn and Sarah J. Hainer
    Citation: BMC Genomics 2023 24:201
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:699

  50. The auxin indole-3-acetic acid (IAA) is a vital phytohormone that influences plant growth and development. Our previous work showed that IAA content decreased during flower development in the medicinally impor...

    Authors: Can Si, Danqi Zeng, Jaime A. Teixeira da Silva, Shengxiang Qiu, Jun Duan, Song Bai and Chunmei He
    Citation: BMC Genomics 2023 24:199
    Content type: Research Published on:

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BMC Genomics

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