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6358 result(s) for 'general transcription factors vs specific' within BMC Genomics

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  1. Marrow-derived stromal cells (MSCs) maintain the capability of self-renewal and differentiation into multiple lineages in adult life. Age-related changes are recognized by a decline in the stemness potential t...

    Authors: Uri David Akavia, Irena Shur, Gideon Rechavi and Dafna Benayahu
    Citation: BMC Genomics 2006 7:95
    Content type: Research article Published on:

  3. Many leukemias result from chromosomal rearrangements. The t(8;21) chromosomal translocation produces AML1-ETO, an oncogenic fusion protein that compromises the function of AML1, a transcription factor critica...

    Authors: Daniel J Trombly, Troy W Whitfield, Srivatsan Padmanabhan, Jonathan AR Gordon, Jane B Lian, Andre J van Wijnen, Sayyed K Zaidi, Janet L Stein and Gary S Stein
    Citation: BMC Genomics 2015 16:309
    Content type: Research article Published on:

  4. The genotype information carried by Genome-wide association studies (GWAS) seems to have the potential to explain more of the ‘missing heritability’ of complex human phenotypes, given improved statistical appr...

    Authors: Luiz F Goulart, Francesco Bettella, Ida E Sønderby, Andrew J Schork, Wesley K Thompson, Morten Mattingsdal, Vidar M Steen, Verena Zuber, Yunpeng Wang, Anders M Dale, Ole A Andreassen and Srdjan Djurovic
    Citation: BMC Genomics 2015 16:304
    Content type: Research article Published on:

  5. Early development of an oviparous organism is based on maternally stocked structural, nutritional and regulatory components. These components influence the future developmental potential of an embryo, which is...

    Authors: Teshome Tilahun Bizuayehu, Maren Mommens, Arvind Y. M. Sundaram, Anusha K. S. Dhanasiri and Igor Babiak
    Citation: BMC Genomics 2019 20:315
    Content type: Research article Published on:

  6. We previously reported on the interplay between miR156/SPL13 and WD40–1/DFR to improve response to drought stress in alfalfa (Medicago sativa L.). Here we aimed to investigate whether the role of miR156/SPL13 mod...

    Authors: Biruk A. Feyissa, Justin Renaud, Vida Nasrollahi, Susanne E. Kohalmi and Abdelali Hannoufa
    Citation: BMC Genomics 2020 21:721
    Content type: Research article Published on:

  7. The development of transcriptomic tools has allowed exhaustive description of stress responses. These responses always superimpose a general response associated to growth rate decrease and a specific one corre...

    Authors: Clémentine Dressaire, Emma Redon, Helene Milhem, Philippe Besse, Pascal Loubière and Muriel Cocaign-Bousquet
    Citation: BMC Genomics 2008 9:343
    Content type: Research article Published on:

  8. Chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-seq) is increasingly being applied to study genome-wide binding sites of transcription factors. There is an increasing interest in...

    Authors: Hatice Ulku Osmanbeyoglu, Ryan J Hartmaier, Steffi Oesterreich and Xinghua Lu
    Citation: BMC Genomics 2012 13(Suppl 1):S1
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 13 Supplement 1

  9. Triptolide is a therapeutic diterpenoid derived from the Chinese herb Tripterygium wilfordii Hook f. Triptolide has been shown to induce apoptosis by activation of pro-apoptotic proteins, inhibiting NFkB and c-KI...

    Authors: Lata Chauhan, Gregory D. Jenkins, Neha Bhise, Tanya Feldberg, Taraswi Mitra-Ghosh, Brooke L. Fridley and Jatinder K. Lamba
    Citation: BMC Genomics 2015 16:483
    Content type: Research article Published on:

  10. The recent Xylella fastidiosa subsp. pauca (Xfp) outbreak in olive (Olea europaea) groves in southern Italy is causing a destructive disease denoted Olive Quick Decline Syndrome (OQDS). Field observations disclos...

    Authors: Annalisa Giampetruzzi, Massimiliano Morelli, Maria Saponari, Giuliana Loconsole, Michela Chiumenti, Donato Boscia, Vito N. Savino, Giovanni P. Martelli and Pasquale Saldarelli
    Citation: BMC Genomics 2016 17:475
    Content type: Research article Published on:

  11. Fish has been deemed suitable to study the complex mechanisms of vertebrate skeletogenesis and gilthead seabream (Sparus aurata), a marine teleost with acellular bone, has been successfully used in recent years t...

    Authors: Daniel M Tiago, Vincent Laizé, Luca Bargelloni, Serena Ferraresso, Chiara Romualdi and M Leonor Cancela
    Citation: BMC Genomics 2011 12:310
    Content type: Research article Published on:

  12. Sequences up to several megabases in length have been found to be present in individual genomes but absent in the human reference genome. These sequences may be common in populations, and their absence in the ...

    Authors: Yu Liu, Mehmet Koyutürk, Sean Maxwell, Min Xiang, Martina Veigl, Richard S Cooper, Bamidele O Tayo, Li Li, Thomas LaFramboise, Zhenghe Wang, Xiaofeng Zhu and Mark R Chance
    Citation: BMC Genomics 2014 15:685
    Content type: Research article Published on:

  13. The mitochondrial genome is important for studying genome evolution as well as reconstructing the phylogeny of organisms. Complete mitochondrial genome sequences have been reported for more than 2200 metazoans...

    Authors: Hai-Xia Chen, Shi-Chun Sun, Per Sundberg, Wei-Cheng Ren and Jon L Norenburg
    Citation: BMC Genomics 2012 13:139
    Content type: Research article Published on:

  14. MADS-box transcription factors, besides being involved in floral organ specification, have also been implicated in several aspects of plant growth and development. In recent years, there have been reports on g...

    Authors: Rita Arora, Pinky Agarwal, Swatismita Ray, Ashok Kumar Singh, Vijay Pal Singh, Akhilesh K Tyagi and Sanjay Kapoor
    Citation: BMC Genomics 2007 8:242
    Content type: Research article Published on:

  15. Transcriptome sequencing is an effective tool to reveal the essential genes and pathways underlying countless biotic and abiotic stress adaptation mechanisms. Although severely challenged by diverse environmen...

    Authors: Grace Afumwaa Boamah, Zekun Huang, Yawei Shen, Yisha Lu, Zhixuan Wang, Ying Su, Changan Xu, Xuan Luo, Caihuan Ke and Weiwei You
    Citation: BMC Genomics 2022 23:392
    Content type: Research Published on:

  16. Although rapeseed (Brassica napus L.) mutant forming multiple siliques was morphologically described and considered to increase the silique number per plant, an important agronomic trait in this crop, the molecul...

    Authors: Liang Chai, Jinfang Zhang, Kun Lu, Haojie Li, Lintao Wu, Hongshen Wan, Benchuan Zheng, Cheng Cui, Jun Jiang and Liangcai Jiang
    Citation: BMC Genomics 2019 20:304
    Content type: Research article Published on:

  17. We have previously identified associations between major histocompatibility complex (MHC) class I and resistance towards bacterial and viral pathogens in Atlantic salmon. To evaluate if only MHC or also closel...

    Authors: Morten F Lukacs, Håvard Harstad, Unni Grimholt, Marianne Beetz-Sargent, Glenn A Cooper, Linda Reid, Hege G Bakke, Ruth B Phillips, Kristina M Miller, William S Davidson and Ben F Koop
    Citation: BMC Genomics 2007 8:251
    Content type: Research article Published on:

  18. Post-translational modification of histones resulting in chromatin remodelling plays a key role in the regulation of gene expression. Here we report characteristic patterns of expression of 12 members of 3 cla...

    Authors: Hilal Özdağ, Andrew E Teschendorff, Ahmed Ashour Ahmed, Sarah J Hyland, Cherie Blenkiron, Linda Bobrow, Abhi Veerakumarasivam, Glynn Burtt, Tanya Subkhankulova, Mark J Arends, V Peter Collins, David Bowtell, Tony Kouzarides, James D Brenton and Carlos Caldas
    Citation: BMC Genomics 2006 7:90
    Content type: Research article Published on:

  19. Thoroughbred horses have been selected for traits contributing to speed and stamina for centuries. It is widely recognized that inherited variation in physical and physiological characteristics is responsible ...

    Authors: Emmeline W Hill, Beatrice A McGivney, Jingjing Gu, Ronan Whiston and David E MacHugh
    Citation: BMC Genomics 2010 11:552
    Content type: Research article Published on:

  20. Cia5a is a locus on rat chromosome 10 that regulates disease severity and joint damage in two models of rheumatoid arthritis, collagen- and pristane-induced arthritis (PIA). In this study, we aimed to identify ce...

    Authors: Max Brenner and Pércio S Gulko
    Citation: BMC Genomics 2012 13:710
    Content type: Research article Published on:

  21. Pattern-oriented chemical profiling is increasingly being used to characterize the phytochemical composition of herbal medicines for quality control purposes. Ideally, a fingerprint of the biological effects s...

    Authors: Rebekah Cook, James R Hennell, Samiuela Lee, Cheang S Khoo, Maria C Carles, Vincent J Higgins, Suresh Govindaraghavan and Nikolaus J Sucher
    Citation: BMC Genomics 2013 14:445
    Content type: Research article Published on:

  23. Studies on vertebrate DNA methylomes have revealed a regulatory role of tissue specific DNA methylation in relation to gene expression. However, it is not well known how tissue-specific methylation varies betw...

    Authors: Martijn F. L. Derks, Kyle M. Schachtschneider, Ole Madsen, Elio Schijlen, Koen J. F. Verhoeven and Kees van Oers
    Citation: BMC Genomics 2016 17:332
    Content type: Research article Published on:

  24. Induced resistance (IR) can be part of a sustainable plant protection strategy against important plant diseases. β-aminobutyric acid (BABA) can induce resistance in a wide range of plants against several types...

    Authors: Therese Bengtsson, Deborah Weighill, Estelle Proux-Wéra, Fredrik Levander, Svante Resjö, Dharani Dhar Burra, Laith Ibrahim Moushib, Pete E Hedley, Erland Liljeroth, Dan Jacobson, Erik Alexandersson and Erik Andreasson
    Citation: BMC Genomics 2014 15:315
    Content type: Research article Published on:

  25. Atlantic salmon production in Tasmania (Southern Australia) occurs near the upper limits of the species thermal tolerance. Summer water temperatures can average over 19 °C over several weeks and have negative eff...

    Authors: Waldo G. Nuez-Ortín, Chris G. Carter, Peter D. Nichols, Ira R. Cooke and Richard Wilson
    Citation: BMC Genomics 2018 19:133
    Content type: Research article Published on:

  26. Pseudomonas putida is a model organism for bioremediation because of its remarkable metabolic versatility, extensive biodegradative functions, and ubiquity in contaminated soil environments. To further the unders...

    Authors: Dorothea K Thompson, Karuna Chourey, Gene S Wickham, Stephanie B Thieman, Nathan C VerBerkmoes, Bing Zhang, Andrea T McCarthy, Matt A Rudisill, Manesh Shah and Robert L Hettich
    Citation: BMC Genomics 2010 11:311
    Content type: Research article Published on:

  27. MicroRNAs (miRNAs) are endogenous, small (21–25 nucleotide), non-coding RNAs that play important roles in numerous biological processes. Koi carp exhibit diverse color patterns, making it an ideal subject for ...

    Authors: Mingkun Luo, Lanmei Wang, Wenbin Zhu, Jianjun Fu, Feibiao Song, Min Fang, Juanjuan Dong and Zaijie Dong
    Citation: BMC Genomics 2018 19:779
    Content type: Research article Published on:

  28. In eukaryotes, transcriptional regulation is usually mediated by interactions of multiple transcription factors (TFs) with their respective specific cis-regulatory elements (CREs) in the so-called cis-regulatory ...

    Authors: Meng Niu, Ehsan S Tabari and Zhengchang Su
    Citation: BMC Genomics 2014 15:1047
    Content type: Methodology article Published on:

  29. Hop (Humulus lupulus L.) plants are grown primarily for the brewing industry and have been used as a traditional medicinal herb for a long time. Severe hop stunt disease caused by the recently discovered Citrus b...

    Authors: Ajay Kumar Mishra, Ganesh Selvaraj Duraisamy, Jaroslav Matoušek, Sebastjan Radisek, Branka Javornik and Jernej Jakse
    Citation: BMC Genomics 2016 17:919
    Content type: Research article Published on:

  30. MicroRNAs play an important role in many fundamental biological and pathological processes. Defining the microRNAs profile underlying the processes by beneficial and detrimental lifestyles, including caloric r...

    Authors: Huan Gong, Ming Zhang, Yiwen Han, Ying Zhang, Jing Pang, Yanyang Zhao, Beidong Chen, Wei Wu, Ruomei Qi and Tiemei Zhang
    Citation: BMC Genomics 2021 22:196
    Content type: Research article Published on:

  31. The mitochondrial (mt) genome has been used as an effective tool for phylogenetic and population genetic analyses in vertebrates. However, the structure and variability of the vertebrate mt genome are not well...

    Authors: Takashi P. Satoh, Masaki Miya, Kohji Mabuchi and Mutsumi Nishida
    Citation: BMC Genomics 2016 17:719
    Content type: Research article Published on:

  32. A complete understanding of the genetic basis for sexual determination and differentiation is necessary in order to implement efficient breeding schemes at early stages of development. Atlantic salmon belongs ...

    Authors: María Gabián, Paloma Morán, Ana I. Fernández, Beatriz Villanueva, Amel Chtioui, Matthew P. Kent, Lara Covelo-Soto, Almudena Fernández and María Saura
    Citation: BMC Genomics 2019 20:764
    Content type: Research article Published on:

  33. Histone H3 lysine 4 tri-methylation (H3K4me3) and histone H3 lysine 9 tri-methylation (H3K9me3) are widely perceived to be opposing and often mutually exclusive chromatin modifications. However, both are neede...

    Authors: Qiaoqiao Zhu, Mukund Ramakrishnan, Jinhee Park and William J. Belden
    Citation: BMC Genomics 2019 20:350
    Content type: Research article Published on:

  35. Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns of gene expression ...

    Authors: Rayner González-Prendes, Raquel Quintanilla, Emilio Mármol-Sánchez, Ramona N. Pena, Maria Ballester, Tainã Figueiredo Cardoso, Arianna Manunza, Joaquim Casellas, Ángela Cánovas, Isabel Díaz, José Luis Noguera, Anna Castelló, Anna Mercadé and Marcel Amills
    Citation: BMC Genomics 2019 20:170
    Content type: Research article Published on:

  36. Sulforaphane is a natural isothiocyanate available from cruciferous vegetables with multiple characteristics including antioxidant, antitumor and anti-inflammatory effect. Single-molecule real-time (SMRT) sequ...

    Authors: Qiuyun Wu, Junwei Wang, Shuxiang Mao, Haoran Xu, Qi Wu, Mantian Liang, Yiming Yuan, Mingyue Liu and Ke Huang
    Citation: BMC Genomics 2019 20:377
    Content type: Research article Published on:

  37. Hepatocellular carcinoma (HCC) in young subjects is rare but more devastating. We hypothesize that genes and etiological pathways are unique to young HCC (yHCC; ≤40 years old at diagnosis) patients. We therefo...

    Authors: Hsei-Wei Wang, Tsung-Han Hsieh, SSu-Yi Huang, Gar-Yang Chau, Chien-Yi Tung, Chien-Wei Su and Jaw-Ching Wu
    Citation: BMC Genomics 2013 14:736
    Content type: Research article Published on:

  38. Various saprotrophic microorganisms, especially filamentous fungi, can efficiently degrade lignocellulose that is one of the most abundant natural materials on earth. It consists of complex carbohydrates and a...

    Authors: Youzhi Miao, Dongyang Liu, Guangqi Li, Pan Li, Yangchun Xu, Qirong Shen and Ruifu Zhang
    Citation: BMC Genomics 2015 16:459
    Content type: Research article Published on:

  40. Transposable elements (TE) comprise nearly half of the human genome and their insertions have profound effects to human genetic diversification and as well as disease. Despite their abovementioned significance...

    Authors: Matias I. Autio, Talal Bin Amin, Arnaud Perrin, Jen Yi Wong, Roger S.-Y. Foo and Shyam Prabhakar
    Citation: BMC Genomics 2021 22:789
    Content type: Methodology article Published on:

  41. The fish pathogen Aliivibrio salmonicida is the causative agent of cold-water vibriosis in marine aquaculture. The Gram-negative bacterium causes tissue degradation, hemolysis and sepsis in vivo.

    Authors: Erik Hjerde, Marit Sjo Lorentzen, Matthew TG Holden, Kathy Seeger, Steinar Paulsen, Nathalie Bason, Carol Churcher, David Harris, Halina Norbertczak, Michael A Quail, Suzanne Sanders, Scott Thurston, Julian Parkhill, Nils Peder Willassen and Nicholas R Thomson
    Citation: BMC Genomics 2008 9:616
    Content type: Research article Published on:

  42. Common bean (Phaseolus vulgaris L.) is the most important legume cropped worldwide for food production and its agronomic performance can be greatly improved if the benefits from symbiotic nitrogen fixation are ma...

    Authors: Ernesto Ormeño-Orrillo, Douglas Fabiano Gomes, Pablo del Cerro, Ana Tereza Ribeiro Vasconcelos, Carlos Canchaya, Luiz Gonzaga Paula Almeida, Fabio Martins Mercante, Francisco Javier Ollero, Manuel Megías and Mariangela Hungria
    Citation: BMC Genomics 2016 17:534
    Content type: Research article Published on:

  43. Psychrotrophic lactic acid bacteria (LAB) species are the dominant species in the microbiota of cold-stored modified-atmosphere-packaged food products and are the main cause of food spoilage. Despite the impor...

    Authors: Ilhan Cem Duru, Anne Ylinen, Sergei Belanov, Alan Avila Pulido, Lars Paulin and Petri Auvinen
    Citation: BMC Genomics 2021 22:28
    Content type: Research article Published on:

  44. The microsporidia parasite Nosema contributes to the steep global decline of honey bees that are critical pollinators of food crops. There are two species of Nosema that have been found to infect honey bees, Nose...

    Authors: Yan ping Chen, Jeffery S Pettis, Yan Zhao, Xinyue Liu, Luke J Tallon, Lisa D Sadzewicz, Renhua Li, Huoqing Zheng, Shaokang Huang, Xuan Zhang, Michele C Hamilton, Stephen F Pernal, Andony P Melathopoulos, Xianghe Yan and Jay D Evans
    Citation: BMC Genomics 2013 14:451
    Content type: Research article Published on:

  45. The ability to establish root nodule symbioses is restricted to four different plant orders. Soil actinobacteria of the genus Frankia can establish a symbiotic relationship with a diverse group of plants within e...

    Authors: Thanh Van Nguyen, Daniel Wibberg, Kai Battenberg, Jochen Blom, Brian Vanden Heuvel, Alison M. Berry, Jörn Kalinowski and Katharina Pawlowski
    Citation: BMC Genomics 2016 17:796
    Content type: Research article Published on:

  46. Benzo [a]pyrene (B[a]P) exposure induces DNA adducts at all stages of spermatogenesis and in testis, and removal of these lesions is less efficient in nucleotide excision repair deficient Xpc-/- mice than in wild...

    Authors: Nicole Verhofstad, Jeroen LA Pennings, Conny ThM van Oostrom, Jan van Benthem, Frederik J van Schooten, Harry van Steeg and Roger WL Godschalk
    Citation: BMC Genomics 2010 11:333
    Content type: Research article Published on:

  47. Improving the yield and fiber quality of upland cotton is a goal of plant breeders. However, increasing the yield and quality of cotton fibers is becoming more urgent. While the growing human population needs ...

    Authors: Yuan Qin, Huiru Sun, Pengbo Hao, Hantao Wang, Congcong Wang, Liang Ma, Hengling Wei and Shuxun Yu
    Citation: BMC Genomics 2019 20:633
    Content type: Research article Published on:

  48. Alternative splicing is an important step in gene expression, generating multiple isoforms for the same genes and greatly expanding the diversity of proteomes. Genetic variation in alternative splicing contrib...

    Authors: Fei Zhang, Deborah Velez-Irizarry, Catherine W. Ernst and Wen Huang
    Citation: BMC Genomics 2023 24:240
    Content type: Research Published on:

  49. The major medicinal alkaloids isolated from Uncaria rhynchophylla (gouteng in chinese) capsules are rhynchophylline (RIN) and isorhynchophylline (IRN). Extracts containing these terpene indole alkaloids (TIAs) ca...

    Authors: Qianqian Guo, Xiaojun Ma, Shugen Wei, Deyou Qiu, Iain W Wilson, Peng Wu, Qi Tang, Lijun Liu, Shoukun Dong and Wei Zu
    Citation: BMC Genomics 2014 15:676
    Content type: Research article Published on:

  50. Pinpointing genes involved in inherited human diseases remains a great challenge in the post-genomics era. Although approaches have been proposed either based on the guilt-by-association principle or making us...

    Authors: Rui Jiang, Mengmeng Wu and Lianshuo Li
    Citation: BMC Genomics 2015 16(Suppl 2):S3
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 16 Supplement 2

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BMC Genomics

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