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6358 result(s) for 'general transcription factors vs specific' within BMC Genomics

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  1. Mutations in the mitochondrial genome have been implicated in mitochondrial disease, often characterized by impaired cellular energy metabolism. Cellular energy metabolism in mitochondria involves mitochondria...

    Authors: Jigme Dorji, Christy J. Vander Jagt, Josie B. Garner, Leah C. Marett, Brett A. Mason, Coralie M. Reich, Ruidong Xiang, Emily L. Clark, Benjamin G. Cocks, Amanda J. Chamberlain, Iona M. MacLeod and Hans D. Daetwyler
    Citation: BMC Genomics 2020 21:720
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Genomics 2022 23:315

  2. The marine alga Ulva compressa is the dominant species in coastal areas receiving effluents from copper mines. The alga can accumulate high amounts of copper and possesses a strong antioxidant system. Here, we pe...

    Authors: Felipe E. Rodríguez, Daniel Laporte, Alberto González, Katterinne N. Mendez, Eduardo Castro-Nallar, Claudio Meneses, Juan Pablo Huidobro-Toro and Alejandra Moenne
    Citation: BMC Genomics 2018 19:829
    Content type: Research article Published on:

  3. Clonostachys rosea is an established biocontrol agent. Selected strains have either mycoparasitic activity against known pathogens (e.g. Fusarium species) and/or plant growth promoting activity on various crops. ...

    Authors: Adilah Bahadoor, Kelly A. Robinson, Michele C. Loewen and Zerihun A. Demissie
    Citation: BMC Genomics 2023 24:352
    Content type: Research Published on:

  4. Penicillium chrysogenum has been used in producing penicillin and derived β-lactam antibiotics for many years. Although the genome of the mutant strain P. chrysogenum Wisconsin 54-1255 has already been sequenced,...

    Authors: Qin Peng, Yihui Yuan, Meiying Gao, Xupeng Chen, Biao Liu, Pengming Liu, Yan Wu and Dandan Wu
    Citation: BMC Genomics 2014 15:144
    Content type: Research article Published on:

  5. Prokaryotic CRISPR-Cas systems confer resistance to viral infection and thus mediate bacteria-phage interactions. However, the distribution and functional diversity of CRISPRs among environmental bacteria rema...

    Authors: Matthias Wietz, Natalie Millán-Aguiñaga and Paul R Jensen
    Citation: BMC Genomics 2014 15:936
    Content type: Research article Published on:

  6. Cytoplasmic male sterility (CMS) is very important in hybrid breeding. The restorer-of-fertility (Rf) nuclear genes rescue the sterile phenotype. Most of the Rf genes encode pentatricopeptide repeat (PPR) protein...

    Authors: Luyun Ning, Hao Wang, Dianrong Li, Yonghong Li, Kang Chen, Hongbo Chao, Huaixin Li, Jianjie He and Maoteng Li
    Citation: BMC Genomics 2020 21:765
    Content type: Research article Published on:

  7. The bacterial cell wall is the target of many antibiotics and cell envelope constituents are critical to host-pathogen interactions. To combat resistance development and virulence, a detailed knowledge of the ...

    Authors: Judith Hübscher, Lucas Lüthy, Brigitte Berger-Bächi and Patricia Stutzmann Meier
    Citation: BMC Genomics 2008 9:617
    Content type: Research article Published on:

  8. Blood-sucking lice (suborder Anoplura) parasitize eutherian mammals with 67% of the 540 described species found on rodents. The five species of blood-sucking lice that infest humans and pigs have fragmented mi...

    Authors: Wen-Ge Dong, Simon Song, Dao-Chao Jin, Xian-Guo Guo and Renfu Shao
    Citation: BMC Genomics 2014 15:44
    Content type: Research article Published on:

  9. Low oxygen availability has been shown previously to stimulate M. tuberculosis to establish non-replicative persistence in vitro. The two component sensor/regulator dosRS is a major mediator in the transcriptiona...

    Authors: Yi Zhang, Kim A Hatch, Lorenz Wernisch and Joanna Bacon
    Citation: BMC Genomics 2008 9:87
    Content type: Research article Published on:

  10. Emerging pathogenic bacteria are an increasing threat to public health. Two recently described species of the genus Aliarcobacter, A. faecis and A. lanthieri, isolated from human or livestock feces, are closely r...

    Authors: Jiacheng Chuan, Anatoly Belov, Michel Cloutier, Xiang Li, Izhar U. H. Khan and Wen Chen
    Citation: BMC Genomics 2022 23:471
    Content type: Research Published on:

  11. Seasonal timing of breeding is a life history trait with major fitness consequences but the genetic basis of the physiological mechanism underlying it, and how gene expression is affected by date and temperatu...

    Authors: Veronika N. Laine, Irene Verhagen, A. Christa Mateman, Agata Pijl, Tony D. Williams, Phillip Gienapp, Kees van Oers and Marcel E. Visser
    Citation: BMC Genomics 2019 20:693
    Content type: Research article Published on:

  12. RNA-Seq is currently the most widely used tool to analyze whole-transcriptome profiles. There are numerous commercial kits available to facilitate preparing RNA-Seq libraries; however, it is still not clear ho...

    Authors: Hsueh-Ping Chao, Yueping Chen, Yoko Takata, Mary W. Tomida, Kevin Lin, Jason S. Kirk, Melissa S. Simper, Carol D. Mikulec, Joyce E. Rundhaug, Susan M. Fischer, Taiping Chen, Dean G. Tang, Yue Lu and Jianjun Shen
    Citation: BMC Genomics 2019 20:571
    Content type: Methodology article Published on:

  13. Appropriate protein subcellular localization is essential for proper cellular function. Central to the regulation of protein localization are protein targeting motifs, stretches of amino acids serving as guide...

    Authors: Mikael-Jonathan Luce, Anna Akuvi Akpawu, Daniel C. Tucunduva, Spencer Mason and Michelle S. Scott
    Citation: BMC Genomics 2016 17:472
    Content type: Research article Published on:

  14. Multi-genome comparative analysis has yielded important insights into the molecular details of gene regulation. We have developed EvoPrinter, a web-accessed genomics tool that provides a single uninterrupted view...

    Authors: Amarendra S Yavatkar, Yong Lin, Jermaine Ross, Yang Fann, Thomas Brody and Ward F Odenwald
    Citation: BMC Genomics 2008 9:106
    Content type: Methodology article Published on:

  15. Lactobacillus plantarum is a normal, potentially probiotic, inhabitant of the human gastrointestinal (GI) tract. The bacterium has great potential as food-grade cell factory and for in situ delivery of biomolecul...

    Authors: Geir Mathiesen, Anita Sveen, May Bente Brurberg, Lasse Fredriksen, Lars Axelsson and Vincent GH Eijsink
    Citation: BMC Genomics 2009 10:425
    Content type: Research article Published on:

  16. Identification of protein-protein interactions is a fundamental aspect of understanding protein function. A commonly used method for identifying protein interactions is the yeast two-hybrid system.

    Authors: Jennifer D Lewis, Janet Wan, Rachel Ford, Yunchen Gong, Pauline Fung, Hardeep Nahal, Pauline W Wang, Darrell Desveaux and David S Guttman
    Citation: BMC Genomics 2012 13:8
    Content type: Research article Published on:

  17. Under limited iron (Fe) availability maize, a Strategy II plant, improves Fe acquisition through the release of phytosiderophores (PS) into the rhizosphere and the subsequent uptake of Fe-PS complexes into root c...

    Authors: Laura Zanin, Silvia Venuti, Anita Zamboni, Zeno Varanini, Nicola Tomasi and Roberto Pinton
    Citation: BMC Genomics 2017 18:154
    Content type: Research article Published on:

  18. Vespa velutina, one of the most aggressive and fearful wasps in China, can cause grievous allergies and toxic reactions, leading to organ failure and even death. However, there is little evidence on molecular dat...

    Authors: Junjie Tan, Wenbo Wang, Fan Wu, Yunming Li and Quanshui Fan
    Citation: BMC Genomics 2020 21:427
    Content type: Research article Published on:

  19. Dinoflagellates are one of the most important classes of marine and freshwater algae, notable both for their functional diversity and ecological significance. They occur naturally as free-living cells, as endo...

    Authors: Deana L Erdner and Donald M Anderson
    Citation: BMC Genomics 2006 7:88
    Content type: Research article Published on:

  20. Although a number of intestinal inflammatory conditions pertain to the ileum, whole-genome gene expression analyses in animal models of ileal inflammation are lacking to date. Therefore, we aimed to identify a...

    Authors: Leela Rani Avula, Dries Knapen, Roeland Buckinx, Lucia Vergauwen, Dirk Adriaensen, Luc Van Nassauw and Jean-Pierre Timmermans
    Citation: BMC Genomics 2012 13:377
    Content type: Research article Published on:

  21. Accurate evaluation of the quality of genomic or proteomic data and computational methods is vital to our ability to use them for formulating novel biological hypotheses and directing further experiments. Ther...

    Authors: Chad L Myers, Daniel R Barrett, Matthew A Hibbs, Curtis Huttenhower and Olga G Troyanskaya
    Citation: BMC Genomics 2006 7:187
    Content type: Research article Published on:

  22. Polyploid species contribute to Oryza diversity. However, the mechanisms underlying gene and genome evolution in Oryza polyploids remain largely unknown. The allotetraploid Oryza minuta, which is estimated to hav...

    Authors: Yi Sui, Bo Li, Jinfeng Shi and Mingsheng Chen
    Citation: BMC Genomics 2014 15:11
    Content type: Research article Published on:

  23. The Fox gene family comprises a large and functionally diverse group of forkhead-related transcriptional regulators, many of which are essential for metazoan embryogenesis and physiology. Defining conserved funct...

    Authors: Sergey Yaklichkin, Alexander Vekker, Steven Stayrook, Mitchell Lewis and Daniel S Kessler
    Citation: BMC Genomics 2007 8:201
    Content type: Research article Published on:

  24. Knowledge of protein-DNA interactions at the structural-level can provide insights into the mechanisms of protein-DNA recognition and gene regulation. Although over 1400 protein-DNA complex structures have bee...

    Authors: RyangGuk Kim and Jun-tao Guo
    Citation: BMC Genomics 2009 10(Suppl 1):S13
    Content type: Research Published on:

    This article is part of a Supplement: Volume 10 Supplement 1

  25. The whiteflies under the name Bemisia tabaci (Gennadius) (Aleyrodidae: Hemiptera) are species complex of at least 31 cryptic species some of which are globally invasive agricultural pests. Previously, the mitocho...

    Authors: Hua-Ling Wang, Jiao Yang, Laura M Boykin, Qiong-Yi Zhao, Qian Li, Xiao-Wei Wang and Shu-Sheng Liu
    Citation: BMC Genomics 2013 14:401
    Content type: Research article Published on:

  26. The ferret (Mustela putorius furo) represents an attractive animal model for the study of respiratory diseases, including influenza. Despite its importance for biomedical research, the number of reagents for mole...

    Authors: Carl E Bruder, Suxia Yao, Francis Larson, Jeremy V Camp, Ronald Tapp, Alexis McBrayer, Nicholas Powers, Willy Valdivia Granda and Colleen B Jonsson
    Citation: BMC Genomics 2010 11:251
    Content type: Research article Published on:

  28. The regulation and function of mammalian RNAs has been increasingly appreciated to operate via RNA-protein interactions. With the recent discovery of thousands of novel human RNA molecules by high-throughput R...

    Authors: Zurab Siprashvili, Dan E Webster, Markus Kretz, Danielle Johnston, John L Rinn, Howard Y Chang and Paul A Khavari
    Citation: BMC Genomics 2012 13:633
    Content type: Methodology article Published on:

  30. Blood flow restoration is a definitive therapy for salvaging the myocardium following ischemic injury. Nevertheless, the sudden restoration of blood flow to the ischemic myocardium can induce ischemia-reperfus...

    Authors: Zanxin Wang, Junmin Wen, Chuzhi Zhou, Zhiwei Wang and Minxin Wei
    Citation: BMC Genomics 2019 20:361
    Content type: Research article Published on:

  31. Zebrafish (Danio rerio) is a prominent vertebrate model of human development and pathogenic disease and has recently been utilized to study teleost immune responses to infectious agents threatening the aquacultur...

    Authors: Dahai Yang, Qin Liu, Minjun Yang, Haizhen Wu, Qiyao Wang, Jingfan Xiao and Yuanxing Zhang
    Citation: BMC Genomics 2012 13:319
    Content type: Research article Published on:

  32. Autophagy, meaning ‘self-eating’, is required for the degradation and recycling of cytoplasmic constituents under stressful and non-stressful conditions, which helps to maintain cellular homeostasis and delay ...

    Authors: Huan Wang, Zhaotang Ding, Mengjie Gou, Jianhui Hu, Yu Wang, Lu Wang, Yuchun Wang, Taimei Di, Xinfu Zhang, Xinyuan Hao, Xinchao Wang, Yajun Yang and Wenjun Qian
    Citation: BMC Genomics 2021 22:121
    Content type: Research article Published on:

  33. Within the genus Streptococcus, only Streptococcus thermophilus is used as a starter culture in food fermentations. Streptococcus macedonicus though, which belongs to the Streptococcus bovis/Streptococcus equinus

    Authors: Konstantinos Papadimitriou, Rania Anastasiou, Eleni Mavrogonatou, Jochen Blom, Nikos C Papandreou, Stavros J Hamodrakas, Stéphanie Ferreira, Pierre Renault, Philip Supply, Bruno Pot and Effie Tsakalidou
    Citation: BMC Genomics 2014 15:272
    Content type: Research article Published on:

  34. In our previous study, we identified four isoforms of the Bmovo gene, Bmovo-1, Bmovo-2, Bmovo-3 and Bmovo-4 from the silkworm ovary and verified that ovarian development was regulated by the BmOVO proteins. Resul...

    Authors: Min Zhu, Xiaolong Hu, Zi Liang, Mengsheng Jiang, Renyu Xue, Yongchang Gong, Xing Zhang, Guangli Cao and Chengliang Gong
    Citation: BMC Genomics 2019 20:342
    Content type: Research article Published on:

  35. In oviparous species accidental variation of incubation temperatures may occur under natural conditions and mechanisms may have evolved by natural selection that facilitate coping with these stressors. However...

    Authors: Watcharapong Naraballobh, Nares Trakooljul, Eduard Muráni, Ronald Brunner, Carsten Krischek, Sabine Janisch, Michael Wicke, Siriluck Ponsuksili and Klaus Wimmers
    Citation: BMC Genomics 2016 17:323
    Content type: Research article Published on:

  36. Vascular endothelial growth factor A (VEGFA) is a major angiogenic factor that plays an important role in the formation of blood vessels during embryonic development. VEGFA has been implicated in the pathophys...

    Authors: Sheila Nabweyambo, Stephen Kanyerezi, John H.-O. Petterson, Fred Ashaba Katabazi, Alfred Ssekagiri, Savannah Mwesigwa, Gerald Mboowa, Faith Nakazzi, Annette Keesiga, Moses Adroma, Freddie Bwanga, Naomi McGovern, Obondo James Sande and Annettee Nakimuli
    Citation: BMC Genomics 2023 24:132
    Content type: Research Published on:

  37. In the animal kingdom, mollusca is an important phylum of the Lophotrochozoa. However, few studies have investigated the molecular cascade of sex determination/early gonadal differentiation within this phylum....

    Authors: Coralie Broquard, Suwansa-ard Saowaros, Mélanie Lepoittevin, Lionel Degremont, Jean-Baptiste Lamy, Benjamin Morga, Abigail Elizur and Anne-Sophie Martinez
    Citation: BMC Genomics 2021 22:609
    Content type: Research article Published on:

  38. Colon cancer occurrence is increasing worldwide, making it the third most frequent cancer. Although many therapeutic options are available and quite efficient at the early stages, survival is strongly decrease...

    Authors: Stéphanie Durand, Killian Trillet, Arnaud Uguen, Aude Saint-Pierre, Catherine Le Jossic-Corcos and Laurent Corcos
    Citation: BMC Genomics 2017 18:758
    Content type: Research article Published on:

  39. Cytoplasmic male sterility (CMS) provides crucial breeding materials that facilitate hybrid seed production in various crops, and thus plays an important role in the study of hybrid vigor (heterosis), in plant...

    Authors: Xianlong Ding, Jiajia Li, Hao Zhang, Tingting He, Shaohuai Han, Yanwei Li, Shouping Yang and Junyi Gai
    Citation: BMC Genomics 2016 17:24
    Content type: Research article Published on:

  40. The quail and chicken major histocompatibility complex (Mhc) genomic regions have a similar overall organization but differ markedly in that the quail has an expanded number of duplicated class I, class IIB, natu...

    Authors: Kazuyoshi Hosomichi, Takashi Shiina, Shingo Suzuki, Masayuki Tanaka, Sayoko Shimizu, Shigehisa Iwamoto, Hiromi Hara, Yutaka Yoshida, Jerzy K Kulski, Hidetoshi Inoko and Kei Hanzawa
    Citation: BMC Genomics 2006 7:322
    Content type: Research article Published on:

  41. Comparative genomic and/or transcriptomic analyses involving elasmobranchs remain limited, with genome level comparisons of the elasmobranch immune system to that of higher vertebrates, non-existent. This pape...

    Authors: Nicholas J. Marra, Vincent P. Richards, Angela Early, Steve M. Bogdanowicz, Paulina D. Pavinski Bitar, Michael J. Stanhope and Mahmood S. Shivji
    Citation: BMC Genomics 2017 18:87
    Content type: Research article Published on:

  42. Tan sheep is an indigenous Chinese breed well known for its beautiful curly fleece. One prominent breed characteristic of this sheep breed is that the degree of curliness differs markedly between lambs and adu...

    Authors: Yufang Liu, Jibin Zhang, Qiao Xu, Xiaolong Kang, Kejun Wang, Keliang Wu and Meiying Fang
    Citation: BMC Genomics 2018 19:360
    Content type: Research article Published on:

  43. Acetogenic bacteria constitute promising biocatalysts for the conversion of CO2/H2 or synthesis gas (H2/CO/CO2) into biofuels and value-added biochemicals. These microorganisms are naturally capable of autotrophi...

    Authors: Yoseb Song, Jongoh Shin, Sangrak Jin, Jung-Kul Lee, Dong Rip Kim, Sun Chang Kim, Suhyung Cho and Byung-Kwan Cho
    Citation: BMC Genomics 2018 19:837
    Content type: Research article Published on:

    The Data Descriptor to this article has been published in Scientific Data 2021 8:51

  45. In mammals, fine-tuned regulation of gene expression leads to transcription initiation from diverse transcription start sites (TSSs) and multiple core promoters. Although polysome association is a critical ste...

    Authors: Hua Li, Ling Bai, Hongmei Li, Xinhui Li, Yani Kang, Ningbo Zhang, Jielin Sun and Zhifeng Shao
    Citation: BMC Genomics 2019 20:282
    Content type: Research article Published on:

  46. It is well known that development of prostate cancer (PC) can be attributed to somatic mutations of the genome, acquired within proto-oncogenes or tumor-suppressor genes. What is less well understood is how ge...

    Authors: Jean M. Winter, Natasha L. Curry, Derek M. Gildea, Kendra A. Williams, Minnkyong Lee, Ying Hu and Nigel P. S. Crawford
    Citation: BMC Genomics 2018 19:450
    Content type: Research article Published on:

  47. The molecular mechanisms underlying stress-influenced immune function of chicken (Gallus Gallus) are not clear. The stress models can be established effectively by feeding chickens corticosterone (CORT) hormone. ...

    Authors: Yanhua Zhang, Yanting Zhou, Guirong Sun, Kui Li, Zhuanjian Li, Aru Su, Xiaojun Liu, Guoxi Li, Ruirui Jiang, Ruili Han, Yadong Tian, Xiangtao Kang and Fengbin Yan
    Citation: BMC Genomics 2018 19:918
    Content type: Research article Published on:

  48. Microdeletion of chromosome 22q11 is associated with significant developmental anomalies, including disruption of the cardiac outflow tract, thymic/parathyroid aplasia and cleft palate. Amongst the genes withi...

    Authors: Maria Zoupa, Guilherme Machado Xavier, Stephanie Bryan, Ioannis Theologidis, Matthew Arno and Martyn T. Cobourne
    Citation: BMC Genomics 2018 19:429
    Content type: Research article Published on:

  49. The newly discovered reversible N6-methyladenosine (m6A) modification plays an important regulatory role in gene expression. Long non-coding RNAs (lncRNAs) participate in Marek’s disease virus (MDV) replication b...

    Authors: Aijun Sun, Xiaojing Zhu, Ying Liu, Rui Wang, Shuaikang Yang, Man Teng, Luping Zheng, Jun Luo, Gaiping Zhang and Guoqing Zhuang
    Citation: BMC Genomics 2021 22:296
    Content type: Research Published on:

  50. Despite initial response in adjuvant chemotherapy, ovarian cancer patients treated with the combination of paclitaxel and carboplatin frequently suffer from recurrence after few cycles of treatment, and the un...

    Authors: Fang-Han Hsu, Erchin Serpedin, Tzu-Hung Hsiao, Alexander JR Bishop, Edward R Dougherty and Yidong Chen
    Citation: BMC Genomics 2012 13(Suppl 6):S13
    Content type: Research Published on:

    This article is part of a Supplement: Volume 13 Supplement 6

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