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  1. Rice feeds much of the world, and possesses the simplest genome analyzed to date within the grass family, making it an economically relevant model system for other cereal crops. Although the rice genome is seq...

    Authors: Shiguo Zhou, Michael C Bechner, Michael Place, Chris P Churas, Louise Pape, Sally A Leong, Rod Runnheim, Dan K Forrest, Steve Goldstein, Miron Livny and David C Schwartz
    Citation: BMC Genomics 2007 8:278
  2. Diagnostics and disease-management strategies require technologies to enable the simultaneous detection and quantification of a wide range of pathogenic microorganisms. Most multiplex, quantitative detection m...

    Authors: Ronald van Doorn, Marianna Szemes, Peter Bonants, George A Kowalchuk, Joana F Salles, Elen Ortenberg and Cor D Schoen
    Citation: BMC Genomics 2007 8:276
  3. Allele-specific (AS) Polymerase Chain Reaction is a convenient and inexpensive method for genotyping Single Nucleotide Polymorphisms (SNPs) and mutations. It is applied in many recent studies including populat...

    Authors: Pongsakorn Wangkumhang, Kridsadakorn Chaichoompu, Chumpol Ngamphiw, Uttapong Ruangrit, Juntima Chanprasert, Anunchai Assawamakin and Sissades Tongsima
    Citation: BMC Genomics 2007 8:275
  4. Photodynamic therapy (PDT) involves systemic or topical administration of a lesion-localizing photosensitizer or its precursor, followed by irradiation of visible light to cause singlet oxygen-induced damage t...

    Authors: Lina Cekaite, Qian Peng, Andrew Reiner, Susan Shahzidi, Siri Tveito, Ingegerd E Furre and Eivind Hovig
    Citation: BMC Genomics 2007 8:273
  5. The basidiomycete fungus Microbotryum violaceum is responsible for the anther-smut disease in many plants of the Caryophyllaceae family and is a model in genetics and evolutionary biology. Infection is initiated ...

    Authors: Roxana Yockteng, Sylvain Marthey, Hélène Chiapello, Annie Gendrault, Michael E Hood, François Rodolphe, Benjamin Devier, Patrick Wincker, Carole Dossat and Tatiana Giraud
    Citation: BMC Genomics 2007 8:272
  6. The majority of the genes involved in the inflammatory response are highly conserved in mammals. These genes are not significantly expressed under normal conditions and are mainly regulated at the transcriptio...

    Authors: Daniel Rico, Juan M Vaquerizas, Hernán Dopazo and Lisardo Boscá
    Citation: BMC Genomics 2007 8:271
  7. Macaca mulatta is one of the most utilized non-human primate species in biomedical research offering unique behavioral, neuroanatomical, and neurobiochemcial similarities to humans. This makes it a unique organis...

    Authors: Nilesh S Tannu and Scott E Hemby
    Citation: BMC Genomics 2007 8:270
  8. The guppy, Poecilia reticulata, is a well-known model organism for studying inheritance and variation of male ornamental traits as well as adaptation to different river habitats. However, genomic resources for st...

    Authors: Christine Dreyer, Margarete Hoffmann, Christa Lanz, Eva-Maria Willing, Markus Riester, Norman Warthmann, Andrea Sprecher, Namita Tripathi, Stefan R Henz and Detlef Weigel
    Citation: BMC Genomics 2007 8:269
  9. The Down syndrome phenotype has been attributed to overexpression of chromosome 21 (Hsa21) genes. However, the expression profile of Hsa21 genes in trisomic human subjects as well as their effects on genes loc...

    Authors: Anna Conti, Floriana Fabbrini, Paola D'Agostino, Rosa Negri, Dario Greco, Rita Genesio, Maria D'Armiento, Carlo Olla, Dario Paladini, Mariastella Zannini and Lucio Nitsch
    Citation: BMC Genomics 2007 8:268
  10. Fasting has dramatic effects on small intestinal transport function. However, little is known on expression of intestinal transport and phase I/II metabolism genes during fasting and the role the fatty acid-ac...

    Authors: Heleen M van den Bosch, Meike Bünger, Philip J de Groot, Jolanda van der Meijde, Guido JEJ Hooiveld and Michael Müller
    Citation: BMC Genomics 2007 8:267
  11. Although genes play a key role in many complex diseases, the specific genes involved in most complex diseases remain largely unidentified. Their discovery will hinge on the identification of key sequence varia...

    Authors: Jacob L McCauley, Shannon J Kenealy, Elliott H Margulies, Nathalie Schnetz-Boutaud, Simon G Gregory, Stephen L Hauser, Jorge R Oksenberg, Margaret A Pericak-Vance, Jonathan L Haines and Douglas P Mortlock
    Citation: BMC Genomics 2007 8:266
  12. Human myelopoiesis is an exciting biological model for cellular differentiation since it represents a plastic process where multipotent stem cells gradually limit their differentiation potential, generating di...

    Authors: Francesco Ferrari, Stefania Bortoluzzi, Alessandro Coppe, Dario Basso, Silvio Bicciato, Roberta Zini, Claudia Gemelli, Gian Antonio Danieli and Sergio Ferrari
    Citation: BMC Genomics 2007 8:264
  13. Target-primed (non-LTR) retrotransposons, such as the human L1 element, are mobile genetic elements found in many eukaryotic genomes. They are often present in large numbers and their retrotransposition can ca...

    Authors: Timothy JD Goodwin, Jason N Busby and Russell TM Poulter
    Citation: BMC Genomics 2007 8:263
  14. Reference genome sequences within the major taxa can be used to assist the development of genomic tools for related organisms. A major constraint in the use of these sequenced and annotated genomes is divergen...

    Authors: Jeffry L Shultz, Sikander Ali, Linda Ballard and David A Lightfoot
    Citation: BMC Genomics 2007 8:262
  15. In Streptomyces coelicolor, bldA encodes the only tRNA for a rare leucine codon, UUA. This tRNA is unnecessary for growth, but is required for some aspects of secondary metabolism and morphological development. W...

    Authors: Andy Hesketh, Giselda Bucca, Emma Laing, Fiona Flett, Graham Hotchkiss, Colin P Smith and Keith F Chater
    Citation: BMC Genomics 2007 8:261
  16. In plants, complex regulatory mechanisms are at the core of physiological and developmental processes. The phytohormone abscisic acid (ABA) is involved in the regulation of various such processes, including st...

    Authors: Judith L Gómez-Porras, Diego Mauricio Riaño-Pachón, Ingo Dreyer, Jorge E Mayer and Bernd Mueller-Roeber
    Citation: BMC Genomics 2007 8:260
  17. The epidermal growth factor receptor (EGFR/HER1) and its downstream signaling events are important for regulating cell growth and behavior in many epithelial tumors types. In breast cancer, the role of EGFR is...

    Authors: Katherine A Hoadley, Victor J Weigman, Cheng Fan, Lynda R Sawyer, Xiaping He, Melissa A Troester, Carolyn I Sartor, Thais Rieger-House, Philip S Bernard, Lisa A Carey and Charles M Perou
    Citation: BMC Genomics 2007 8:258
  18. The primary regulator of spermatogenesis, a highly ordered and tightly regulated developmental process, is an intrinsic genetic program involving male germ cell-specific genes.

    Authors: Eunyoung Choi, Jiae Lee, Jungsu Oh, Inju Park, Cecil Han, Chongil Yi, Do Han Kim, Byung-Nam Cho, Edward M Eddy and Chunghee Cho
    Citation: BMC Genomics 2007 8:256
  19. The completion of the Plasmodium falciparum genome represents a milestone in malaria research. The genome sequence allows for the development of genome-wide approaches such as microarray and proteomics that will ...

    Authors: Fangli Lu, Hongying Jiang, Jinhui Ding, Jianbing Mu, Jesus G Valenzuela, José MC Ribeiro and Xin-zhuan Su
    Citation: BMC Genomics 2007 8:255
  20. Radiation hybrid (RH) maps are considered to be a tool of choice for fine mapping closely linked loci, considering that the resolution of linkage maps is determined by the number of informative meiosis and rec...

    Authors: Elisa Marques, Simon de Givry, Paul Stothard, Brenda Murdoch, Zhiquan Wang, James Womack and Stephen S Moore
    Citation: BMC Genomics 2007 8:254
  21. We have previously identified associations between major histocompatibility complex (MHC) class I and resistance towards bacterial and viral pathogens in Atlantic salmon. To evaluate if only MHC or also closel...

    Authors: Morten F Lukacs, Håvard Harstad, Unni Grimholt, Marianne Beetz-Sargent, Glenn A Cooper, Linda Reid, Hege G Bakke, Ruth B Phillips, Kristina M Miller, William S Davidson and Ben F Koop
    Citation: BMC Genomics 2007 8:251
  22. Trichophyton rubrum is the most common dermatophyte species and the most frequent cause of fungal skin infections in humans worldwide. It's a major concern because feet and nail infections caused by this organism...

    Authors: Jian Yang, Lihong Chen, Lingling Wang, Wenliang Zhang, Tao Liu and Qi Jin
    Citation: BMC Genomics 2007 8:250
  23. The sequencing of the D.melanogaster genome revealed an unexpected small number of genes (~ 14,000) indicating that mechanisms acting on generation of transcript diversity must have played a major role in the evo...

    Authors: Rafaela M Maia, Valeria Valente, Marco AV Cunha, Josane F Sousa, Daniela D Araujo, Wilson A Silva Jr, Marco A Zago, Emmanuel Dias-Neto, Sandro J Souza, Andrew JG Simpson, Nadia Monesi, Ricardo GP Ramos, Enilza M Espreafico and Maria L Paçó-Larson
    Citation: BMC Genomics 2007 8:249
  24. The completion and reporting of baculovirus genomes is extremely important as it advances our understanding of gene function and evolution. Due to the large number of viral genomes now sequenced it is very imp...

    Authors: Zuo-Ming Nie, Zhi-Fang Zhang, Dan Wang, Ping-An He, Cai-Ying Jiang, Li Song, Fang Chen, Jie Xu, Ling Yang, Lin-Lin Yu, Jian Chen, Zheng-Bing Lv, Jing-Jing Lu, Xiang-Fu Wu and Yao-Zhou Zhang
    Citation: BMC Genomics 2007 8:248
  25. Folate synthesis and salvage pathways are relatively well known from classical biochemistry and genetics but they have not been subjected to comparative genomic analysis. The availability of genome sequences f...

    Authors: Valérie de Crécy-Lagard, Basma El Yacoubi, Rocío Díaz de la Garza, Alexandre Noiriel and Andrew D Hanson
    Citation: BMC Genomics 2007 8:245
  26. Within the last decade a large number of noncoding RNA genes have been identified, but this may only be the tip of the iceberg. Using comparative genomics a large number of sequences that have signals concorda...

    Authors: Christian Weile, Paul P Gardner, Mads M Hedegaard and Jeppe Vinther
    Citation: BMC Genomics 2007 8:244
  27. MADS-box transcription factors, besides being involved in floral organ specification, have also been implicated in several aspects of plant growth and development. In recent years, there have been reports on g...

    Authors: Rita Arora, Pinky Agarwal, Swatismita Ray, Ashok Kumar Singh, Vijay Pal Singh, Akhilesh K Tyagi and Sanjay Kapoor
    Citation: BMC Genomics 2007 8:242
  28. The family Camelidae that evolved in North America during the Eocene survived with two distinct tribes, Camelini and Lamini. To investigate the evolutionary relationship between them and to further understand ...

    Authors: Peng Cui, Rimutu Ji, Feng Ding, Dan Qi, Hongwei Gao, He Meng, Jun Yu, Songnian Hu and Heping Zhang
    Citation: BMC Genomics 2007 8:241
  29. At present, nothing is known of the role of miRNAs in the immune response in vivo despite the fact that inflammation is thought to underlie multiple acute and chronic diseases. In these circumstances, patients ar...

    Authors: Sterghios A Moschos, Andrew E Williams, Mark M Perry, Mark A Birrell, Maria G Belvisi and Mark A Lindsay
    Citation: BMC Genomics 2007 8:240
  30. Transcriptional profiling after herbivore attack reveals, at the molecular level, how plants respond to this type of biotic stress. Comparing herbivore-induced transcriptional responses of plants with differen...

    Authors: Colette Broekgaarden, Erik H Poelman, Greet Steenhuis, Roeland E Voorrips, Marcel Dicke and Ben Vosman
    Citation: BMC Genomics 2007 8:239
  31. Studies of association methods using DNA pooling of single nucleotide polymorphisms (SNPs) have focused primarily on the effects of "machine-error", number of replicates, and the size of the pool. We use the n...

    Authors: Fei Ji, Stephen J Finch, Chad Haynes, Nancy R Mendell and Derek Gordon
    Citation: BMC Genomics 2007 8:238
  32. Abdominal aortic aneurysms are a common disorder with an incompletely understood etiology. We used Illumina and Affymetrix microarray platforms to generate global gene expression profiles for both aneurysmal (...

    Authors: Guy M Lenk, Gerard Tromp, Shantel Weinsheimer, Zoran Gatalica, Ramon Berguer and Helena Kuivaniemi
    Citation: BMC Genomics 2007 8:237
  33. Mutations in the human polycystic kidney disease-1 (hPKD1) gene result in ~85% of cases of autosomal dominant polycystic kidney disease, the most frequent human monogenic disease. PKD1 proteins are large multidom...

    Authors: H Jayantha Gunaratne, Gary W Moy, Masashi Kinukawa, Shinji Miyata, Silvia A Mah and Victor D Vacquier
    Citation: BMC Genomics 2007 8:235
  34. In a mammalian host, the cell surface of African trypanosomes is protected by a monolayer of a single variant surface glycoprotein (VSG). The VSG is central to antigenic variation; one VSG gene is expressed at...

    Authors: O Clyde Hutchinson, Kim Picozzi, Nicola G Jones, Helen Mott, Reuben Sharma, Susan C Welburn and Mark Carrington
    Citation: BMC Genomics 2007 8:234
  35. The CSL (C BF1/RBP-Jκ/S uppressor of Hairless/L AG-1) transcription factor family members are well-known components of the transmembrane receptor Notch signaling pathway, which plays a critical role in metazoan d...

    Authors: Martin Převorovský, František Půta and Petr Folk
    Citation: BMC Genomics 2007 8:233
  36. In situ hybridization (ISH) is a powerful method for visualizing gene expression patterns at the organismal level with cellular resolution. When automated, it is capable of determining the expression of a large n...

    Authors: Murat Cankaya, Ana Martinez Hernandez, Mehmet Ciftci, Sukru Beydemir, Hasan Ozdemir, Harun Budak, Ilhami Gulcin, Veysel Comakli, Tufan Emircupani, Deniz Ekinci, Muslum Kuzu, Qiuhong Jiang, Gregor Eichele and Omer Irfan Kufrevioglu
    Citation: BMC Genomics 2007 8:232
  37. Phylogenetic and functional analysis was conducted on an Anopheles gambiae gene, ENSANGG00000017398. Based on phylogenetic analysis, this gene belongs to the same lineage as Heat shock protein cognate 70-4 (Hsc70...

    Authors: Cheolho Sim, Young S Hong, Konstantin A Tsetsarkin, Dana L Vanlandingham, Stephen Higgs and Frank H Collins
    Citation: BMC Genomics 2007 8:231
  38. Voltage-gated Na+ channel β1 (Scn1b) subunits are multi-functional proteins that play roles in current modulation, channel cell surface expression, cell adhesion, cell migration, and neurite outgrowth. We have sh...

    Authors: Amanda J Fein, Laurence S Meadows, Chunling Chen, Emily A Slat and Lori L Isom
    Citation: BMC Genomics 2007 8:226

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