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  1. Tissue-specific fat deposition is regulated by a series of complex regulatory mechanisms. Reports indicate that epigenetic regulators, such as circular RNAs (circRNAs), are crucial in diseases progression, ani...

    Authors: Meng Zhang, Yu Han, Yanhui Zhai, Xiangfei Ma, Xinglan An, Sheng Zhang and Ziyi Li

    Citation: BMC Genomics 2020 21:594

    Content type: Research article

    Published on:

  2. Duplications of large genomic segments provide genetic diversity in genome evolution. Despite their importance, how these duplications are generated remains uncertain, particularly for distant duplicated genom...

    Authors: Javier U. Chicote, Marcos López-Sánchez, Tomàs Marquès-Bonet, José Callizo, Luis A. Pérez-Jurado and Antonio García-España

    Citation: BMC Genomics 2020 21:593

    Content type: Research article

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  3. The DGAT1 gene encodes an enzyme responsible for catalysing the terminal reaction in mammary triglyceride synthesis, and underpins a well-known pleiotropic quantitative trait locus (QTL) with a large influence on...

    Authors: Tania Fink, Thomas J. Lopdell, Kathryn Tiplady, Renee Handley, Thomas J. J. Johnson, Richard J. Spelman, Stephen R. Davis, Russell G. Snell and Mathew D. Littlejohn

    Citation: BMC Genomics 2020 21:591

    Content type: Research article

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  4. Prolonged exposure to elevated free fatty acids induces β-cell failure (lipotoxicity) and contributes to the pathogenesis of type 2 diabetes. In vitro exposure of β-cells to the saturated free fatty acid palmi...

    Authors: Maria Lytrivi, Kassem Ghaddar, Miguel Lopes, Victoria Rosengren, Anthony Piron, Xiaoyan Yi, Henrik Johansson, Janne Lehtiö, Mariana Igoillo-Esteve, Daniel A. Cunha, Lorella Marselli, Piero Marchetti, Henrik Ortsäter, Decio L. Eizirik and Miriam Cnop

    Citation: BMC Genomics 2020 21:590

    Content type: Research article

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  5. More than 2500 species belong to the Meloidae family (Coleoptera: Tenebrionoidea), members of which produce the potent defensive blistering agent cantharidin and are commonly known as blister beetles or Spanishfl...

    Authors: Yuan-Ming Wu, Yang-Yang Liu and Xiang-Sheng Chen

    Citation: BMC Genomics 2020 21:589

    Content type: Research article

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  6. Antagonistic co-evolution can drive rapid adaptation in pathogens and shape genome architecture. Comparative genome analyses of several fungal pathogens revealed highly variable genomes, for many species chara...

    Authors: Alice Feurtey, Cécile Lorrain, Daniel Croll, Christoph Eschenbrenner, Michael Freitag, Michael Habig, Janine Haueisen, Mareike Möller, Klaas Schotanus and Eva H. Stukenbrock

    Citation: BMC Genomics 2020 21:588

    Content type: Research article

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  7. Alternative splicing (AS) offers a main mechanism to form protein polymorphism. A growing body of evidence indicates the correlation between splicing disorders and carcinoma. Nevertheless, an overall analysis ...

    Authors: Yuanyuan Zhang, Shengling Ma, Qian Niu, Yun Han, Xingyu Liu, Jie Jiang, Simiao Chen and Haolong Lin

    Citation: BMC Genomics 2020 21:580

    Content type: Research article

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  8. M. morganii is a bacterium frequently associated with urinary infections in humans. While many human strains are sequenced, only the genomes of few poultry strains are available. Here, we performed a detailed cha...

    Authors: Nicola Palmieri, Claudia Hess, Michael Hess and Merima Alispahic

    Citation: BMC Genomics 2020 21:579

    Content type: Research article

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  9. Transcription factor (TF) GAMYB, belonging to MYB family (named after the gene of the avian myeloblastosis virus) is a master gibberellin (GA)-induced regulatory protein that is crucial for development and germin...

    Authors: Anna Bienias, Magdalena Góralska, Piotr Masojć, Paweł Milczarski and Beata Myśków

    Citation: BMC Genomics 2020 21:578

    Content type: Research article

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  10. Drought is one of the most adverse environmental factors limiting crop productions and it is important to identify key genetic determinants for food safety. Calcium-dependent protein kinases (CPKs) are known t...

    Authors: Ge-Zi Li, Han-Xiao Li, Meng-Jun Xu, Peng-Fei Wang, Xiang-Hong Xiao and Guo-Zhang Kang

    Citation: BMC Genomics 2020 21:577

    Content type: Research article

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  11. A balanced constitutional reciprocal translocation (RT) is a mutual exchange of terminal segments of two non-homologous chromosomes without any loss or gain of DNA in germline cells. Carriers of balanced RTs a...

    Authors: Aniek C. Bouwman, Martijn F. L. Derks, Marleen L. W. J. Broekhuijse, Barbara Harlizius and Roel F. Veerkamp

    Citation: BMC Genomics 2020 21:576

    Content type: Research article

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  12. Cotton (Gossypium spp.) is the most important world-wide fiber crop but salt stress limits cotton production in coastal and other areas. Growth regulation factors (GRFs) play regulatory roles in response to salt ...

    Authors: Jun-Feng Cao, Jin-Quan Huang, Xia Liu, Chao-Chen Huang, Zi-Shou Zheng, Xiu-Fang Zhang, Xiao-Xia Shangguan, Ling-Jian Wang, Yu-Gao Zhang, Jonathan F. Wendel, Corrinne E. Grover and Zhi-Wen Chen

    Citation: BMC Genomics 2020 21:575

    Content type: Research article

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  13. Blue mold is a globally important and economically impactful postharvest disease of apples caused by multiple Penicillium spp. There are currently four postharvest fungicides registered for blue mold control, and...

    Authors: Franz J. Lichtner, Verneta L. Gaskins, Kerik D. Cox and Wayne M. Jurick II

    Citation: BMC Genomics 2020 21:574

    Content type: Research article

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  14. ERF transcription factors (TFs) belong to the Apetala2/Ethylene responsive Factor (AP2/ERF) TF family and play a vital role in plant growth and development processes. Capsorubin and capsaicinoids have relative...

    Authors: Jiali Song, Changming Chen, Shuanglin Zhang, Juntao Wang, Zhubing Huang, Muxi Chen, Bihao Cao, Zhangsheng Zhu and Jianjun Lei

    Citation: BMC Genomics 2020 21:573

    Content type: Research article

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  15. As air temperatures increase globally, more and more plants are exposed to heat-stress conditions. Although many studies have explored regulation networks in plants with the aim of improving their heat-stress ...

    Authors: Jiahong Xu, Yao Zheng, Shouqin Pu, Xiujie Zhang, Zhihao Li and Jinhui Chen

    Citation: BMC Genomics 2020 21:572

    Content type: Research article

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  16. The investigation of transcriptome profiles using short reads in non-model organisms, which lack of well-annotated genomes, is limited by partial gene reconstruction and isoform detection. In contrast, long-re...

    Authors: Giuseppe D. Puglia, Andrey D. Prjibelski, Domenico Vitale, Elena Bushmanova, Karl J. Schmid and Salvatore A. Raccuia

    Citation: BMC Genomics 2020 21:317

    Content type: Research article

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  17. Queen failure is a persistent problem in beekeeping operations, but in the absence of overt symptoms it is often difficult, if not impossible, to ascertain the root cause. Stressors like heat-shock, cold-shock...

    Authors: Alison McAfee, Joseph Milone, Abigail Chapman, Leonard J. Foster, Jeffery S. Pettis and David R. Tarpy

    Citation: BMC Genomics 2020 21:571

    Content type: Research article

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  18. Laurel wilt caused by Raffaelea lauricola is a lethal vascular disease of North American members of the Lauraceae plant family. This fungus and its primary ambrosia beetle vector Xyleborus glabratus originated fr...

    Authors: Yucheng Zhang, Junli Zhang, Dan Vanderpool, Jason A. Smith and Jeffrey A. Rollins

    Citation: BMC Genomics 2020 21:570

    Content type: Research article

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  19. Members of the bacterial family Flavobacteriaceae are widely distributed in the marine environment and often found associated with algae, fish, detritus or marine invertebrates. Yet, little is known about the cha...

    Authors: Asimenia Gavriilidou, Johanna Gutleben, Dennis Versluis, Francesca Forgiarini, Mark W. J. van Passel, Colin J. Ingham, Hauke Smidt and Detmer Sipkema

    Citation: BMC Genomics 2020 21:569

    Content type: Research article

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  20. The nosocomial pathogen Enterococcus faecium can survive for prolonged periods of time on surfaces in the absence of nutrients. This trait is thought to contribute to the ability of E. faecium to spread among pat...

    Authors: Vincent de Maat, Sergio Arredondo-Alonso, Rob J. L. Willems and Willem van Schaik

    Citation: BMC Genomics 2020 21:568

    Content type: Research article

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  21. The only licensed live Bacille Calmette-Guérin (BCG) vaccine used to prevent severe childhood tuberculosis comprises genetically divergent strains with variable protective efficacy and rates of BCG-induced adv...

    Authors: Olga Narvskaya, Daria Starkova, Diana Levi, Natalia Alexandrova, Vladimir Molchanov, Ekaterina Chernyaeva, Anna Vyazovaya, Alexander Mushkin, Viacheslav Zhuravlev, Natalia Solovieva, Boris Vishnevskiy and Igor Mokrousov

    Citation: BMC Genomics 2020 21:567

    Content type: Research article

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  22. Common bacterial blight (CBB) caused by Xanthomonas phaseoli pv. phaseoli and Xanthomonas citri pv. fuscans is one of the major threats to common bean crops (Phaseolus vulgaris L.). Resistance to CBB is particula...

    Authors: Justine Foucher, Mylène Ruh, Anne Préveaux, Sébastien Carrère, Sandra Pelletier, Martial Briand, Rémy-Félix Serre, Marie-Agnès Jacques and Nicolas W. G. Chen

    Citation: BMC Genomics 2020 21:566

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Genomics 2020 21:657

  24. Shiga toxin-producing E. coli (STECs) are foodborne pathogens associated with bloody diarrhea and hemolytic uremic syndrome (HUS). Although the STEC O157 serogroup accounts for the highest number of infections, H...

    Authors: Julio A. Guerra, Chengxian Zhang, Jonathan E. Bard, Donald Yergeau, Natasha Halasa and Oscar G. Gómez-Duarte

    Citation: BMC Genomics 2020 21:564

    Content type: Research article

    Published on:

  25. The ubiquitous presence of short tandem repeats (STRs) in virtually all genomes implicates their functional relevance, while a widely-accepted definition of STR is yet to be established. Previous studies major...

    Authors: Hongxi Zhang, Douyue Li, Xiangyan Zhao, Saichao Pan, Xiaolong Wu, Shan Peng, Hanrou Huang, Ruixue Shi and Zhongyang Tan

    Citation: BMC Genomics 2020 21:563

    Content type: Research article

    Published on:

  26. Enterohemorrhagic Escherichia coli O157:H7 (EHEC) is a significant foodborne pathogen that resides asymptomatically within cattle and other ruminants. The EHEC genome harbors an extensive collection of mobile gen...

    Authors: Eliot Stanton, Taylor A. Wahlig, Dongjin Park and Charles W. Kaspar

    Citation: BMC Genomics 2020 21:562

    Content type: Research article

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  27. GGPP (geranylgeranyl diphosphate) is produced in the isoprenoid pathway and mediates the function of various plant metabolites, which is synthesized by GGPPS (GGPP synthases) in plants. GGPPS characterization has...

    Authors: Faiza Ali, Ghulam Qanmber, Zhenzhen Wei, Daoqian Yu, Yong hui Li, Lei Gan, Fuguang Li and Zhi Wang

    Citation: BMC Genomics 2020 21:561

    Content type: Research article

    Published on:

  28. High temperatures, particularly at night, decrease rice yield and quality. As high nighttime temperatures (HNTs) become increasingly frequent due to climate change, it is imperative to develop rice crops that ...

    Authors: Chao He, Hong-Yu Zhang, Yong-Xin Zhang, Pei Fu, Li-Li You, Wen-Bo Xiao, Zhao-Hai Wang, Hai-Yan Song, Ying-Jin Huang and Jiang-Lin Liao

    Citation: BMC Genomics 2020 21:560

    Content type: Research article

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  29. Mud crab, Scylla paramamosain, a euryhaline crustacean species, mainly inhabits the Indo-Western Pacific region. Wild mud crab spawn in high-salt condition and the salinity reduced with the growth of the hatching...

    Authors: Yin Zhang, Qingyang Wu, Shaobin Fang, Shengkang Li, Huaiping Zheng, Yueling Zhang, Mhd Ikhwanuddin and Hongyu Ma

    Citation: BMC Genomics 2020 21:559

    Content type: Research article

    Published on:

  30. Rainbow trout is a significant fish farming species under temperate climates. Female reproduction traits play an important role in the economy of breeding companies with the sale of fertilized eggs. The object...

    Authors: J. D’Ambrosio, R. Morvezen, S. Brard-Fudulea, A. Bestin, A. Acin Perez, D. Guéméné, C. Poncet, P. Haffray, M. Dupont-Nivet and F. Phocas

    Citation: BMC Genomics 2020 21:558

    Content type: Research article

    Published on:

  32. Tea plant is one of the most important non-alcoholic beverage crops worldwide. While potassium (K+) is an essential macronutrient and greatly affects the growth and development of plants, the molecular mechanism ...

    Authors: Tianyuan Yang, Xin Lu, Yan Wang, Yunxia Xie, Jingzhen Ma, Xunmin Cheng, Enhua Xia, Xiaochun Wan and Zhaoliang Zhang

    Citation: BMC Genomics 2020 21:556

    Content type: Research article

    Published on:

  33. Statins are widely prescribed to lower plasma low-density lipoprotein cholesterol levels. Though statins reduce cardiovascular disease risk overall, statin efficacy varies, and some people experience adverse s...

    Authors: Elizabeth Theusch, Yii-Der I. Chen, Jerome I. Rotter, Ronald M. Krauss and Marisa W. Medina

    Citation: BMC Genomics 2020 21:555

    Content type: Research article

    Published on:

  34. Advances in next-generation sequencing technologies have provided an opportunity to perform population-level comparative genomic analysis to discover unique genomic characteristics of domesticated animals. Duc...

    Authors: Daehwan Lee, Jongin Lee, Kang-Neung Heo, Kisang Kwon, Youngbeen Moon, Dajeong Lim, Kyung-Tai Lee and Jaebum Kim

    Citation: BMC Genomics 2020 21:554

    Content type: Research article

    Published on:

  35. The reblooming bearded iris (Iris germanica) can bloom twice a year, in spring and autumn. The extended ornamental period makes it more popular and brings additional commercial values. However, little is known ab...

    Authors: Zhuping Fan, Yike Gao, Yi Ren, Chunjing Guan, Rong Liu and Qixiang Zhang

    Citation: BMC Genomics 2020 21:553

    Content type: Research article

    Published on:

  36. Goldfish is an important model for various areas of research, including neural development and behavior and a species of significant importance in aquaculture, especially as an ornamental species. It has a mal...

    Authors: Ming Wen, Romain Feron, Qiaowei Pan, Justine Guguin, Elodie Jouanno, Amaury Herpin, Christophe Klopp, Cedric Cabau, Margot Zahm, Hugues Parrinello, Laurent Journot, Shawn M. Burgess, Yoshihiro Omori, John H. Postlethwait, Manfred Schartl and Yann Guiguen

    Citation: BMC Genomics 2020 21:552

    Content type: Research article

    Published on:

  37. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Satoru Onizuka, Yasuharu Yamazaki, Sung-Joon Park, Takayuki Sugimoto, Yumiko Sone, Sebastian Sjöqvist, Michihiko Usui, Akira Takeda, Kenta Nakai, Keisuke Nakashima and Takanori Iwata

    Citation: BMC Genomics 2020 21:551

    Content type: Correction

    Published on:

    The original article was published in BMC Genomics 2020 21:417

  38. Saline, alkaline, and saline-alkaline stress severely affect plant growth and development. The tolerance of plants to these stressors has long been important breeding objectives, especially for woody perennial...

    Authors: Jing Liu, Fei Shen, Yao Xiao, Hongcheng Fang, Changpeng Qiu, Wei Li, Ting Wu, Xuefeng Xu, Yi Wang, Xinzhong Zhang and Zhenhai Han

    Citation: BMC Genomics 2020 21:550

    Content type: Research article

    Published on:

  40. Coral reefs are among the most diverse, complex and densely populated marine ecosystems. To survive, morphologically simple and sessile cnidarians have developed mechanisms to catch prey, deter predators and c...

    Authors: Oshra Yosef, Yotam Popovits, Assaf Malik, Maya Ofek-Lalzer, Tali Mass and Daniel Sher

    Citation: BMC Genomics 2020 21:548

    Content type: Research article

    Published on:

  41. The Asian tiger mosquito, Aedes albopictus, is a highly dangerous invasive vector of numerous medically important arboviruses including dengue, chikungunya and Zika. In four decades it has spread from tropical So...

    Authors: Ludvik M. Gomulski, Mosè Manni, Davide Carraretto, Tony Nolan, Daniel Lawson, José M. Ribeiro, Anna R. Malacrida and Giuliano Gasperi

    Citation: BMC Genomics 2020 21:547

    Content type: Research article

    Published on:

  42. Many insects can develop differential biotypes on variable host plants, but the underlying molecular factors and mechanisms are not well understood. To address this issue, transcriptome profiling analyses were...

    Authors: Da Wang, Deguang Liu, Xiaoqin Shi, Yujing Yang, Na Zhang and Zheming Shang

    Citation: BMC Genomics 2020 21:546

    Content type: Research article

    Published on:

  43. Genomic selection has been successfully implemented in many livestock and crop species. The genomic best linear unbiased predictor (GBLUP) approach, assigning equal variance to all SNP effects, is one of the r...

    Authors: José Luis Gualdrón Duarte, Ann-Stephan Gori, Xavier Hubin, Daniela Lourenco, Carole Charlier, Ignacy Misztal and Tom Druet

    Citation: BMC Genomics 2020 21:545

    Content type: Research article

    Published on:

  44. Full chloroplast genomes provide high resolution taxonomic discrimination between closely related plant species and are quickly replacing single and multi-locus barcoding regions as reference materials of choi...

    Authors: Jorge Villacrés-Vallejo, José Aranda-Ventura, Anna Wallis, Robin Cagle, Sara M. Handy, Jeffery Davis, Elizabeth Reed, Shu Zhang, Errol Strain, Monica Pava-Ripoll, David Erickson, Padmini Ramachandran and Andrea Ottesen

    Citation: BMC Genomics 2020 21:544

    Content type: Research article

    Published on:

  45. Polar bears are uniquely adapted to an Arctic existence. Since their relatively recent divergence from their closest living relative, brown bears, less than 500,000 years ago, the species has evolved an array ...

    Authors: Jose Alfredo Samaniego Castruita, Michael V. Westbury and Eline D. Lorenzen

    Citation: BMC Genomics 2020 21:543

    Content type: Research article

    Published on:

  47. The development of genome-wide genotyping resources has provided terrestrial livestock and crop industries with the unique ability to accurately assess genomic relationships between individuals, uncover the ge...

    Authors: Jarrod L. Guppy, David B. Jones, Shannon R. Kjeldsen, Agnes Le Port, Mehar S. Khatkar, Nicholas M. Wade, Melony J. Sellars, Eike J. Steinig, Herman W. Raadsma, Dean R. Jerry and Kyall R. Zenger

    Citation: BMC Genomics 2020 21:541

    Content type: Methodology article

    Published on:

  48. The South African claw-toed frog, Xenopus laevis, is uniquely suited for studying differences between regenerative and non-regenerative responses to CNS injury within the same organism, because some CNS neurons (...

    Authors: Jamie L. Belrose, Aparna Prasad, Morgan A. Sammons, Kurt M. Gibbs and Ben G. Szaro

    Citation: BMC Genomics 2020 21:540

    Content type: Research article

    Published on:

  49. Closely related species of the carp family (Cyprinidae) have evolved distinctive abilities to survive under cold stress, but molecular mechanisms underlying the generation of cold resistance remain largely unknow...

    Authors: Guodong Ge, Yong Long, Lianyu Shi, Jing Ren, Junjun Yan, Chitao Li, Qing Li and Zongbin Cui

    Citation: BMC Genomics 2020 21:539

    Content type: Research article

    Published on:

  50. Greying of the hair is an obvious sign of human aging. In addition to age, sex- and ancestry-specific patterns of hair greying are also observed and the progression of greying may be affected by environmental ...

    Authors: Ewelina Pośpiech, Magdalena Kukla-Bartoszek, Joanna Karłowska-Pik, Piotr Zieliński, Anna Woźniak, Michał Boroń, Michał Dąbrowski, Magdalena Zubańska, Agata Jarosz, Tomasz Grzybowski, Rafał Płoski, Magdalena Spólnicka and Wojciech Branicki

    Citation: BMC Genomics 2020 21:538

    Content type: Research article

    Published on:

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