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  2. Actinoplanes sp. SE50/110 is the natural producer of the diabetes mellitus drug acarbose, which is highly produced during the growth phase and ceases during the stationary phase. In previous works, the growth-dep...

    Authors: Julian Droste, Vera Ortseifen, Lena Schaffert, Marcus Persicke, Susanne Schneiker-Bekel, Alfred Pühler and Jörn Kalinowski

    Citation: BMC Genomics 2020 21:818

    Content type: Research article

    Published on:

  4. The gut microbiome can influence life history traits associated with host fitness such as fecundity and longevity. In most organisms, these two life history traits are traded-off, while they are positively lin...

    Authors: Matteo Antoine Negroni, Francisca H. I. D. Segers, Fanny Vogelweith and Susanne Foitzik

    Citation: BMC Genomics 2020 21:816

    Content type: Research article

    Published on:

  5. Malonylation is a recently discovered post-translational modification that is associated with a variety of diseases such as Type 2 Diabetes Mellitus and different types of cancers. Compared with experimental i...

    Authors: Xin Liu, Liang Wang, Jian Li, Junfeng Hu and Xiao Zhang

    Citation: BMC Genomics 2020 21:812

    Content type: Methodology article

    Published on:

  6. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Camilo Breton, Peter M. Clark, Lili Wang, Jenny A. Greig and James M. Wilson

    Citation: BMC Genomics 2020 21:810

    Content type: Correction

    Published on:

    The original article was published in BMC Genomics 2020 21:239

  7. The NBS disease-related gene family coordinates the inherent immune system in plants in response to pathogen infections. Previous studies have identified NBS-encoding genes in Pyrus bretschneideri (‘Dangshansuli’...

    Authors: Manyi Sun, Mingyue Zhang, Jugpreet Singh, Bobo Song, Zikai Tang, Yueyuan Liu, Runze Wang, Mengfan Qin, Jiaming Li, Awais Khan and Jun Wu

    Citation: BMC Genomics 2020 21:809

    Content type: Research article

    Published on:

  9. Transposable elements (TEs) are fragments of DNA that can insert into new chromosomal locations. They represent a great proportion of eukaryotic genomes. The identification and characterization of TEs facilita...

    Authors: Chia-Chi Hsu, Shu-Yun Chen, Pei-Han Lai, Yu-Yun Hsiao, Wen-Chieh Tsai, Zhong-Jian Liu, Mei-Chu Chung, Olivier Panaud and Hong-Hwa Chen

    Citation: BMC Genomics 2020 21:807

    Content type: Research article

    Published on:

  10. Next-generation sequencing (NGS) is widely used for genome-wide identification and quantification of DNA elements involved in the regulation of gene transcription. Studies that generate multiple high-throughpu...

    Authors: Bronte Wen, Hyun Jun Jung, Lihe Chen, Fahad Saeed and Mark A. Knepper

    Citation: BMC Genomics 2020 21:806

    Content type: Software

    Published on:

  11. With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However, the introduction of plant oil in farmed salmon fe...

    Authors: Yang Jin, Alex K. Datsomor, Rolf E. Olsen, Jon Olav Vik, Jacob S. Torgersen, Rolf B. Edvardsen, Anna Wargelius, Per Winge and Fabian Grammes

    Citation: BMC Genomics 2020 21:805

    Content type: Research article

    Published on:

  12. The tRNAs act as a bridge between the coding mRNA and incoming amino acids during protein translation. The anti-codon of tRNA recognizes the codon of the mRNA and deliver the amino acid into the protein transl...

    Authors: Tapan Kumar Mohanta, Awdhesh Kumar Mishra, Abeer Hashem, Elsayed Fathi Abd_Allah, Abdul Latif Khan and Ahmed Al-Harrasi

    Citation: BMC Genomics 2020 21:804

    Content type: Research article

    Published on:

  13. Eucalyptus, a highly diverse genus of the Myrtaceae family, is the most widely planted hardwood in the world due to its increasing importance for fiber and energy. Somatic embryogenesis (SE) is one large-scale me...

    Authors: Yufei Xiao, Junji Li, Ye Zhang, Xiaoning Zhang, Hailong Liu, Zihai Qin and Bowen Chen

    Citation: BMC Genomics 2020 21:803

    Content type: Research article

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  14. The Robinson-Foulds (RF) distance is a well-established measure between phylogenetic trees. Despite a lack of biological justification, it has the advantages of being a proper metric and being computable in li...

    Authors: Samuel Briand, Christophe Dessimoz, Nadia El-Mabrouk, Manuel Lafond and Gabriela Lobinska

    Citation: BMC Genomics 2020 21(Suppl 10):779

    Content type: Research

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    This article is part of a Supplement: Volume 21 Supplement 10

  15. The emergence of the third generation sequencing technology, featuring longer read lengths, has demonstrated great advancement compared to the next generation sequencing technology and greatly promoted the bio...

    Authors: Jiaqi Liu, Jiayin Wang, Xiao Xiao, Xin Lai, Daocheng Dai, Xuanping Zhang, Xiaoyan Zhu, Zhongmeng Zhao, Juan Wang and Zhimin Li

    Citation: BMC Genomics 2020 21(Suppl 10):753

    Content type: Methodology

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  16. Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao is one of the most common herbs widely used in South and East Asia, to enhance people’s health and reinforce vital energy. Despite its prevalence, however...

    Authors: Xueting Wu, Xuetong Li, Wei Wang, Yuanhong Shan, Cuiting Wang, Mulan Zhu, Qiong La, Yang Zhong, Ye Xu, Peng Nan and Xuan Li

    Citation: BMC Genomics 2020 21(Suppl 10):697

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  17. Immense improvements in sequencing technologies enable producing large amounts of high throughput and cost effective next-generation sequencing (NGS) data. This data needs to be processed efficiently for furth...

    Authors: Tanveer Ahmad, Nauman Ahmed, Zaid Al-Ars and H. Peter Hofstee

    Citation: BMC Genomics 2020 21(Suppl 10):683

    Content type: Software

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  18. Single-cell RNA-sequencing (scRNA-seq) is becoming indispensable in the study of cell-specific transcriptomes. However, in scRNA-seq techniques, only a small fraction of the genes are captured due to “dropout”...

    Authors: Xikang Feng, Lingxi Chen, Zishuai Wang and Shuai Cheng Li

    Citation: BMC Genomics 2020 21(Suppl 10):618

    Content type: Methodology

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  19. Biological evidence has shown that microRNAs(miRNAs) are greatly implicated in various biological progresses involved in human diseases. The identification of miRNA-disease associations(MDAs) is beneficial to ...

    Authors: Huiran Li, Yin Guo, Menglan Cai and Limin Li

    Citation: BMC Genomics 2020 21(Suppl 10):617

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  20. Regulatory hotspots are genetic variations that may regulate the expression levels of many genes. It has been of great interest to find those hotspots utilizing expression quantitative trait locus (eQTL) analy...

    Authors: Ju Hun Choi, Taegun Kim, Junghyun Jung and Jong Wha J. Joo

    Citation: BMC Genomics 2020 21(Suppl 10):616

    Content type: Methodology

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  21. The current computational methods on identifying conserved protein complexes across multiple Protein-Protein Interaction (PPI) networks suffer from the lack of explicit modeling of the desired topological prop...

    Authors: Yijie Wang, Hyundoo Jeong, Byung-Jun Yoon and Xiaoning Qian

    Citation: BMC Genomics 2020 21(Suppl 10):615

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  22. Bivalent promoters marked with both H3K27me3 and H3K4me3 histone modifications are characteristic of poised promoters in embryonic stem (ES) cells. The model of poised promoters postulates that bivalent chroma...

    Authors: Ah-Jung Jeon and Greg Tucker-Kellogg

    Citation: BMC Genomics 2020 21(Suppl 10):614

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  23. Hundreds of genomes and transcriptomes of fish species have been sequenced in recent years. However, fish scholarship currently lacks a comprehensive, integrated, and up-to-date collection of fish genomic data.

    Authors: Liandong Yang, Zetan Xu, Honghui Zeng, Ning Sun, Baosheng Wu, Cheng Wang, Jing Bo, Lin Li, Yang Dong and Shunping He

    Citation: BMC Genomics 2020 21:801

    Content type: Database

    Published on:

  24. Fat tail is a unique trait in sheep acquired during domestication. Several genomic analyses have been conducted in sheep breeds from limited geographic origins to identify the genetic factors underlying this t...

    Authors: Kunzhe Dong, Min Yang, Jiangang Han, Qing Ma, Jilong Han, Ziyi Song, Cuicheng Luosang, Neena Amatya Gorkhali, Bohui Yang, Xiaohong He, Yuehui Ma and Lin Jiang

    Citation: BMC Genomics 2020 21:800

    Content type: Research article

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  25. Common bean is an important staple crop in the tropics of Africa, Asia and the Americas. Particularly smallholder farmers rely on bean as a source for calories, protein and micronutrients. Drought is a major p...

    Authors: Santiago Diaz, Daniel Ariza-Suarez, Paulo Izquierdo, Juan David Lobaton, Juan Fernando de la Hoz, Fernando Acevedo, Jorge Duitama, Alberto F. Guerrero, Cesar Cajiao, Victor Mayor, Stephen E. Beebe and Bodo Raatz

    Citation: BMC Genomics 2020 21:799

    Content type: Research article

    Published on:

  26. Sperm miRNAs were reported to regulate spermatogenesis and early embryonic development in some mammals including bovine. The dairy cattle breeding industry now tends to collect semen from younger bulls under h...

    Authors: Chongyang Wu, Patrick Blondin, Christian Vigneault, Rémi Labrecque and Marc-André Sirard

    Citation: BMC Genomics 2020 21:798

    Content type: Research article

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  27. The archaeal exosome is an exoribonucleolytic multiprotein complex, which degrades single-stranded RNA in 3′ to 5′ direction phosphorolytically. In a reverse reaction, it can add A-rich tails to the 3′-end of ...

    Authors: Jochen Bathke, A. Susann Gauernack, Oliver Rupp, Lennart Weber, Christian Preusser, Marcus Lechner, Oliver Rossbach, Alexander Goesmann, Elena Evguenieva-Hackenberg and Gabriele Klug

    Citation: BMC Genomics 2020 21:797

    Content type: Research article

    Published on:

  28. Genomic selection (GS) or genomic prediction is a promising approach for tree breeding to obtain higher genetic gains by shortening time of progeny testing in breeding programs. As proof-of-concept for Scots p...

    Authors: Ainhoa Calleja-Rodriguez, Jin Pan, Tomas Funda, Zhiqiang Chen, John Baison, Fikret Isik, Sara Abrahamsson and Harry X. Wu

    Citation: BMC Genomics 2020 21:796

    Content type: Research article

    Published on:

  29. Valine-glutamine (VQ) motif-containing proteins play important roles in plant growth, development and abiotic stress response. For many plant species, the VQ genes have been identified and their functions have be...

    Authors: Pengyun Chen, Fei wei, Shuaishuai Cheng, Liang Ma, Hantao Wang, Meng Zhang, Guangzhi Mao, Jianhua Lu, Pengbo Hao, Adeel Ahmad, Lijiao Gu, Qiang Ma, Aimin Wu, Hengling Wei and Shuxun Yu

    Citation: BMC Genomics 2020 21:795

    Content type: Research article

    Published on:

  30. Stevia rebaudiana (Bertoni) is considered one of the most valuable plants because of the steviol glycosides (SGs) that can be extracted from its leaves. Glycosyltransferases (GTs), which can transfer sugar moieti...

    Authors: Shaoshan Zhang, Qiong Liu, Chengcheng Lyu, Jinsong Chen, Renfeng Xiao, Jingtian Chen, Yunshu Yang, Huihui Zhang, Kai Hou and Wei Wu

    Citation: BMC Genomics 2020 21:794

    Content type: Research article

    Published on:

  31. MYB superfamily is one of the most abundant families in plants, which plays important roles in plant growth, development, and productivity. However, to date, researches on MYBs in wheat (Triticum aestivum L.) are...

    Authors: Qiuhui Wei, Rong Chen, Xin Wei, Yuheng Liu, Shujuan Zhao, Xiaopu Yin and Tian Xie

    Citation: BMC Genomics 2020 21:792

    Content type: Research article

    Published on:

  32. RNA interference (RNAi) is a highly conserved, sequence-specific gene silencing mechanism present in Eukaryotes. Three RNAi pathways are known, namely micro-RNA (miRNA), piwi-interacting RNA (piRNA) and short ...

    Authors: Beatrice T. Nganso, Noa Sela and Victoria Soroker

    Citation: BMC Genomics 2020 21:791

    Content type: Research article

    Published on:

  34. Ophiocordyceps sinensis (Berk.) is a well-known entomopathogenic and medicinal fungus. It parasitizes and mummifies the underground ghost moth larvae to produce a fruiting body named Chinese cordyceps. Specific f...

    Authors: Miaomiao Li, Qian Meng, Huan Zhang, Ruihao Shu, Yanni Zhao, Peipei Wu, Xuan Li, Guiling Zhou, Qilian Qin and Jihong Zhang

    Citation: BMC Genomics 2020 21:789

    Content type: Research article

    Published on:

  36. Studying functional divergences between paralogs that originated from genome duplication is a significant topic in investigating molecular evolution. Genes that exhibit basal level cyclic expression patterns i...

    Authors: Yuan Lu, Mikki Boswell, William Boswell, Raquel Ybanez Salinas, Markita Savage, Jose Reyes, Sean Walter, Rebecca Marks, Trevor Gonzalez, Geraldo Medrano, Wesley C. Warren, Manfred Schartl and Ronald B. Walter

    Citation: BMC Genomics 2020 21:787

    Content type: Research article

    Published on:

  37. WRKY transcription factors are a superfamily of regulators involved in diverse biological processes and stress responses in plants. However, there is limited knowledge about the WRKY family in camelina (Camelina ...

    Authors: Yanan Song, Hongli Cui, Ying Shi, Jinai Xue, Chunli Ji, Chunhui Zhang, Lixia Yuan and Runzhi Li

    Citation: BMC Genomics 2020 21:786

    Content type: Research article

    Published on:

  38. Mitochondrial DNA is remarkably polymorphic. This is why animal geneticists survey mitochondrial genomes variations for fundamental and applied purposes. We present here an approach to sequence whole mitochond...

    Authors: Sophie Dhorne-Pollet, Eric Barrey and Nicolas Pollet

    Citation: BMC Genomics 2020 21:785

    Content type: Methodology article

    Published on:

  39. In a previous study, the early ripening of Kyoho grape following H2O2 treatment was explored at the physiological level, but the mechanism by which H2O2 promotes ripening at the molecular level is unclear. To rev...

    Authors: Da-Long Guo, Zhen-Guang Wang, Mao-Song Pei, Li-Li Guo and Yi-He Yu

    Citation: BMC Genomics 2020 21:784

    Content type: Research article

    Published on:

  40. Specific adaptive features including disease resistance and growth abilities in harsh environments are attributed to indigenous cattle breeds of Benin, but these breeds are endangered due to crossbreeding. So ...

    Authors: Sèyi Fridaïus Ulrich Vanvanhossou, Carsten Scheper, Luc Hippolyte Dossa, Tong Yin, Kerstin Brügemann and Sven König

    Citation: BMC Genomics 2020 21:783

    Content type: Research article

    Published on:

  41. Xyloglucan endotransglucosylase/hydrolase genes (XTHs) are a multigene family and play key roles in regulating cell wall extensibility in plant growth and development. Brassica rapa and Brassica oleracea contain ...

    Authors: Di Wu, Anqi Liu, Xiaoyu Qu, Jiayi Liang and Min Song

    Citation: BMC Genomics 2020 21:782

    Content type: Research article

    Published on:

  42. The members of the sucrose non-fermenting 1-related protein kinase 2 (SnRK2) family are specific serine/threonine protein kinases in plants that play important roles in stress signal transduction and adaptatio...

    Authors: Guodong Chen, Jizhong Wang, Xin Qiao, Cong Jin, Weike Duan, Xiaochuan Sun and Juyou Wu

    Citation: BMC Genomics 2020 21:781

    Content type: Research article

    Published on:

  43. Long non-coding RNAs (lncRNAs) play crucial roles in gene regulation at the transcriptional and post-transcriptional levels. LncRNAs are belonging to a large class of transcripts with ≥200 nt in length which d...

    Authors: Serafino M. A. Augustino, Qinglei Xu, Xueqin Liu, Siyuan Mi, Liangyu Shi, Yibing Liu, Hui Wen, Di Wang, Lei Liu, Qin Zhang and Ying Yu

    Citation: BMC Genomics 2020 21:780

    Content type: Research article

    Published on:

  44. Fatty acid desaturases (FADs) introduce a double bond into the fatty acids acyl chain resulting in unsaturated fatty acids that have essential roles in plant development and response to biotic and abiotic stre...

    Authors: Zahra Hajiahmadi, Amin Abedi, Hui Wei, Weibo Sun, Honghua Ruan, Qiang Zhuge and Ali Movahedi

    Citation: BMC Genomics 2020 21:778

    Content type: Research article

    Published on:

  45. Pearl millet, a nutritious food for around 100 million people in Africa and India, displays extensive genetic diversity and a high degree of admixture with wild relatives. Two major morphotypes can be distingu...

    Authors: Oumar Diack, Ghislain Kanfany, Mame Codou Gueye, Ousmane Sy, Amadou Fofana, Hamidou Tall, Desalegn D. Serba, Leila Zekraoui, Cécile Berthouly-Salazar, Yves Vigouroux, Diaga Diouf and Ndjido Ardo Kane

    Citation: BMC Genomics 2020 21:777

    Content type: Research article

    Published on:

  46. Drought-tolerance ensures a crop to maintain life activities and protect cell from damages under dehydration. It refers to diverse mechanisms temporally activated when the crop adapts to drought. However, know...

    Authors: Hui Xia, Xiaosong Ma, Kai Xu, Lei Wang, Hongyan Liu, Liang Chen and Lijun Luo

    Citation: BMC Genomics 2020 21:776

    Content type: Research article

    Published on:

  47. Scylla paramamosain is one of the commercially crucial marine crustaceans belonging to the genus Scylla, which is commonly distributed along the coasts of China, Vietnam, and Japan. Genomic and transcriptomic dat...

    Authors: Na Li, Junming Zhou, Huan Wang, Changkao Mu, Ce Shi, Lei Liu and Chunlin Wang

    Citation: BMC Genomics 2020 21:775

    Content type: Research article

    Published on:

  48. Hibernation in an appropriate environment not only is important for the survival of hibernators in winter, but also is crucial for breeding in the following season for many hibernating species. However, the ge...

    Authors: Jian-Qing Lin, Jun Yu, Hua Jiang, Yi Zhang, Qiu-Hong Wan and Sheng-Guo Fang

    Citation: BMC Genomics 2020 21:774

    Content type: Research article

    Published on:

  49. Information on protein-protein interactions affected by mutations is very useful for understanding the biological effect of mutations and for developing treatments targeting the interactions. In this study, we...

    Authors: Jinchan Qu, Albert Steppi, Dongrui Zhong, Jie Hao, Jian Wang, Pei-Yau Lung, Tingting Zhao, Zhe He and Jinfeng Zhang

    Citation: BMC Genomics 2020 21:773

    Content type: Methodology article

    Published on:

  50. Imputation accuracy among other things depends on the size of the reference panel, the marker’s minor allele frequency (MAF), and the correct placement of single nucleotide polymorphism (SNP) on the reference ...

    Authors: Isis da Costa Hermisdorff, Raphael Bermal Costa, Lucia Galvão de Albuquerque, Hubert Pausch and Naveen Kumar Kadri

    Citation: BMC Genomics 2020 21:772

    Content type: Research article

    Published on:

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