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  1. During natural Trypanosoma brucei infections, the parasites differentiate spontaneously into a non-dividing “stumpy” form when a certain level of parasitaemia is attained. This form is metabolically adapted for r...

    Authors: Julius Mulindwa, Clémentine Mercé, Enock Matovu, John Enyaru and Christine Clayton
    Citation: BMC Genomics 2015 16:1118
  2. The rumen microbiota functions as an effective system for conversion of dietary feed to microbial proteins and volatile fatty acids. In the present study, metagenomic approach was applied to elucidate the buff...

    Authors: Neelam M. Nathani, Amrutlal K. Patel, Chandra Shekar Mootapally, Bhaskar Reddy, Shailesh V. Shah, Pravin M. Lunagaria, Ramesh K. Kothari and Chaitanya G. Joshi
    Citation: BMC Genomics 2015 16:1116
  3. The current extensive use of the domestic goat (Capra hircus) is the result of its medium size and high adaptability as multiple breeds. The extent to which its genetic variability was influenced by early domesti...

    Authors: Licia Colli, Hovirag Lancioni, Irene Cardinali, Anna Olivieri, Marco Rosario Capodiferro, Marco Pellecchia, Marcin Rzepus, Wahid Zamani, Saeid Naderi, Francesca Gandini, Seyed Mohammad Farhad Vahidi, Saif Agha, Ettore Randi, Vincenza Battaglia, Maria Teresa Sardina, Baldassare Portolano…
    Citation: BMC Genomics 2015 16:1115
  4. Micro RNAs are a class of small non coding RNAs of 20–24 nucleotides transcribed as single stranded precursors from MIR gene loci. Initially described as post-transcriptional regulators involved in development...

    Authors: Marília de Castro Rodrigues Pappas, Georgios Joannis Pappas Jr and Dario Grattapaglia
    Citation: BMC Genomics 2015 16:1113
  5. The powdery mildew disease affects thousands of plant species and arguably represents the major fungal threat for many Cucurbitaceae crops, including melon (Cucumis melo L.), watermelon (Citrullus lanatus L.) and...

    Authors: Paolo Iovieno, Giuseppe Andolfo, Adalgisa Schiavulli, Domenico Catalano, Luigi Ricciardi, Luigi Frusciante, Maria Raffaella Ercolano and Stefano Pavan
    Citation: BMC Genomics 2015 16:1112
  6. Rhizobium leguminosarum bv. trifolii is a soil bacterium capable of establishing a symbiotic relationship with red clover (Trifolium pratense). The presence of surface polysaccharides ...

    Authors: Kamila Rachwał, Ewa Matczyńska and Monika Janczarek
    Citation: BMC Genomics 2015 16:1111
  7. Drought tolerance is a complex quantitative trait that involves the coordination of a vast array of genes belonging to different pathways. To identify genes related to the drought-tolerance pathway in rice, we...

    Authors: Ali Moumeni, Kouji Satoh, Ramiah Venuprasad, Rachid Serraj, Arvind Kumar, Hei Leung and Shoshi Kikuchi
    Citation: BMC Genomics 2015 16:1110
  8. Parasites of the genus Leishmania are the causative agents of leishmaniasis, a group of diseases that range in manifestations from skin lesions to fatal visceral disease. The life cycle of Leishmania parasites is...

    Authors: Laura A. L. Dillon, Rahul Suresh, Kwame Okrah, Hector Corrada Bravo, David M. Mosser and Najib M. El-Sayed
    Citation: BMC Genomics 2015 16:1108
  9. Adaptive processes shape the evolution of genomes and the diverse functions of different genomic regions are likely to have an impact on the trajectory and outcome of this evolution. The main underlying hypoth...

    Authors: Paolo Gonthier, Fabiano Sillo, Elisa Lagostina, Angela Roccotelli, Olga Santa Cacciola, Jan Stenlid and Matteo Garbelotto
    Citation: BMC Genomics 2015 16:1107
  10. Francisella tularensis is a select bio-threat agent and one of the most virulent intracellular pathogens known, requiring just a few organisms to establish an infection. Although sever...

    Authors: Anders Wallqvist, Vesna Memišević, Nela Zavaljevski, Rembert Pieper, Seesandra V. Rajagopala, Keehwan Kwon, Chenggang Yu, Timothy A. Hoover and Jaques Reifman
    Citation: BMC Genomics 2015 16:1106
  11. WRKY transcription factors (TFs) constitute one of the largest protein families in higher plants, and its members contain one or two conserved WRKY domains, about 60 amino acid residues with the WRKYGQK sequen...

    Authors: Xiaosan Huang, Kongqing Li, Xiaoyong Xu, Zhenghong Yao, Cong Jin and Shaoling Zhang
    Citation: BMC Genomics 2015 16:1104
  12. Collimonas is a genus belonging to the class of Betaproteobacteria and consists mostly of soil bacteria with the ability to exploit living fungi as food source (mycophagy). Collimonas ...

    Authors: Chunxu Song, Ruth Schmidt, Victor de Jager, Dorota Krzyzanowska, Esmer Jongedijk, Katarina Cankar, Jules Beekwilder, Anouk van Veen, Wietse de Boer, Johannes A. van Veen and Paolina Garbeva
    Citation: BMC Genomics 2015 16:1103
  13. Pumpkin (Cucurbita maxima Duch.) is an economically important crop belonging to the Cucurbitaceae family. However, very few genomic and genetic resources are available for this species. As part of our ongoing eff...

    Authors: Guoyu Zhang, Yi Ren, Honghe Sun, Shaogui Guo, Fan Zhang, Jie Zhang, Haiying Zhang, Zhangcai Jia, Zhangjun Fei, Yong Xu and Haizhen Li
    Citation: BMC Genomics 2015 16:1101
  14. Understanding the mechanisms by which neurons are generated and specified, and how they integrate into functional circuits is key to being able to treat disorders of the nervous system and acute brain trauma. ...

    Authors: Alexandra Tallafuss, Meghan Kelly, Leslie Gay, Dan Gibson, Peter Batzel, Kate V. Karfilis, Judith Eisen, Kryn Stankunas, John H. Postlethwait and Philip Washbourne
    Citation: BMC Genomics 2015 16:1100
  15. Since the development of transcriptome analysis systems, many expression evolution studies characterized evolutionary forces acting on gene expression, without explicit discrimination between global expression...

    Authors: Youko Horiuchi, Yoshiaki Harushima, Hironori Fujisawa, Takako Mochizuki, Masahiro Fujita, Hajime Ohyanagi and Nori Kurata
    Citation: BMC Genomics 2015 16:1099
  16. The identification of factors involved in the host range definition and evolution is a pivotal challenge in the goal to predict and prevent the emergence of plant bacterial disease. To trace the evolution and ...

    Authors: Jonathan L. Gordon, Pierre Lefeuvre, Aline Escalon, Valérie Barbe, Stéphane Cruveiller, Lionel Gagnevin and Olivier Pruvost
    Citation: BMC Genomics 2015 16:1098
  17. There are more than 1 million persons living with HIV/AIDS (PLWHA) in the United States and approximately 40 % of them have a history of alcohol use disorders (AUD). Chronic heavy alcohol consumption and HIV/A...

    Authors: Liz Simon, Andrew D. Hollenbach, Jovanny Zabaleta and Patricia E. Molina
    Citation: BMC Genomics 2015 16:1097
  18. Seminal fluid proteins control many aspects of fertilization and in turn, they play a key role in post-mating sexual selection and possibly reproductive isolation. Because effective proteome profiling relies o...

    Authors: Martha L. Bonilla, Christopher Todd, Martin Erlandson and Jose Andres
    Citation: BMC Genomics 2015 16:1096
  19. The genus Weissella belongs to the lactic acid bacteria and includes 18 currently identified species, predominantly isolated from fermented food but rarely from cases of bacteremia in animals. Recently, a new spe...

    Authors: Henrique C. P. Figueiredo, Siomar C. Soares, Felipe L. Pereira, Fernanda A. Dorella, Alex F. Carvalho, Júnia P. Teixeira, Vasco A. C. Azevedo and Carlos A. G. Leal
    Citation: BMC Genomics 2015 16:1095
  20. The obligate intracellular bacterium Chlamydia pneumoniae is a common respiratory pathogen, which has been found in a range of hosts including humans, marsupials and amphibians. Whole genome comparisons of human

    Authors: Eileen Roulis, Nathan Bachmann, Michael Humphrys, Garry Myers, Wilhelmina Huston, Adam Polkinghorne and Peter Timms
    Citation: BMC Genomics 2015 16:1094
  21. Many differences between different ethnic groups have been observed, such as skin color, eye color, height, susceptibility to some diseases, and response to certain drugs. However, the genetic bases of such di...

    Authors: Tao Huang, Yang Shu and Yu-Dong Cai
    Citation: BMC Genomics 2015 16:1093
  22. Luteimonas abyssi XH031T, which was previously isolated from subseafloor environment of the South Pacific Gyre (SPG), was an aerobic, gram-negative bacterium, and was identified to be ...

    Authors: Li Zhang, Xiaolei Wang, Min Yu, Yanlu Qiao and Xiao-Hua Zhang
    Citation: BMC Genomics 2015 16:1092
  23. Rice represents one the most important foods all over the world. In Europe, Italy is the first rice producer and Italian production is driven by tradition and quality. All main rice grain quality traits, like ...

    Authors: Chiara Biselli, Paolo Bagnaresi, Daniela Cavalluzzo, Simona Urso, Francesca Desiderio, Gabriele Orasen, Alberto Gianinetti, Federico Righettini, Massimo Gennaro, Rosaria Perrini, Manel Ben Hassen, Gian Attilio Sacchi, Luigi Cattivelli and Giampiero Valè
    Citation: BMC Genomics 2015 16:1091
  24. The acquisition of multidrug resistance by Plasmodium falciparum underscores the need to understand the underlying molecular mechanisms so as to counter their impact on malaria control. For the many antimalarials...

    Authors: Sophie H. Adjalley, Daniel Scanfeld, Elyse Kozlowski, Manuel Llinás and David A. Fidock
    Citation: BMC Genomics 2015 16:1090
  25. Fusarium oxysporum is one of the most common fungal pathogens causing soybean root rot and seedling blight in U.S.A. In a recent study, significant variation in aggressiveness was obse...

    Authors: Alessandra Lanubile, Usha K. Muppirala, Andrew J. Severin, Adriano Marocco and Gary P. Munkvold
    Citation: BMC Genomics 2015 16:1089
  26. Campylobacter species are the most prevalent bacterial pathogen causing acute enteritis worldwide. In contrast to Campylobacter jejuni, about 5 % of Campylobacter coli strains exhibit ...

    Authors: Andreas E. Zautner, Anne-Marie Goldschmidt, Andrea Thürmer, Jörg Schuldes, Oliver Bader, Raimond Lugert, Uwe Groß, Kerstin Stingl, Gabriela Salinas and Thomas Lingner
    Citation: BMC Genomics 2015 16:1088
  27. Gibberellin (GA), a classical phytohormone, plays significant roles in plant growth and development. It shares the important intermediate diphosphate precursor, GGPP, with the main lipophilic bioactive compone...

    Authors: Qing Du, Caili Li, Dongqiao Li and Shanfa Lu
    Citation: BMC Genomics 2015 16:1087
  28. The most common ladybird beetle, Coccinella septempunctata L., is an excellent predator of crop pests such as aphids and white flies, and it shows a wide range of adaptability, a large appetite and a high reprodu...

    Authors: Xiaoyang Qi, Lisheng Zhang, Yanhua Han, Xiaoyun Ren, Jian Huang and Hongyin Chen
    Citation: BMC Genomics 2015 16:1086
  29. Clostridium autoethanogenum is an acetogenic bacterium capable of producing high value commodity chemicals and biofuels from the C1 gases present in synthesis gas. This common industri...

    Authors: Christopher M. Humphreys, Samantha McLean, Sarah Schatschneider, Thomas Millat, Anne M. Henstra, Florence J. Annan, Ronja Breitkopf, Bart Pander, Pawel Piatek, Peter Rowe, Alexander T. Wichlacz, Craig Woods, Rupert Norman, Jochen Blom, Alexander Goesman, Charlie Hodgman…
    Citation: BMC Genomics 2015 16:1085
  30. Avoidance of palindromic recognition sites of Type II restriction-modification (R-M) systems was shown for many R-M systems in dozens of prokaryotic genomes. However the phenomenon has not been investigated sy...

    Authors: Ivan Rusinov, Anna Ershova, Anna Karyagina, Sergey Spirin and Andrei Alexeevski
    Citation: BMC Genomics 2015 16:1084
  31. ChIP-seq is highly utilized for mapping histone modifications that are informative about gene regulation and genome annotations. For example, applying ChIP-seq to histone modifications such as H3K4me1 has faci...

    Authors: Cristina Valensisi, Jo Ling Liao, Colin Andrus, Stephanie L. Battle and R. David Hawkins
    Citation: BMC Genomics 2015 16:1083
  32. During the last decade, a great number of extremely valuable large-scale genomics and proteomics datasets have become available to the research community. In addition, dropping costs for conducting high-throug...

    Authors: Christian X. Weichenberger, Hagen Blankenburg, Antonia Palermo, Yuri D’Elia, Eva König, Erik Bernstein and Francisco S. Domingues
    Citation: BMC Genomics 2015 16:1081
  33. The YAC128 model of Huntington’s disease (HD) shows substantial deficits in motor, learning and memory tasks and alterations in its transcriptional profile. We examined the changes in the transcriptional profi...

    Authors: Zubeyde Bayram-Weston, Timothy C. Stone, Peter Giles, Linda Elliston, Nari Janghra, Gemma V. Higgs, Peter A. Holmans, Stephen B. Dunnett, Simon P. Brooks and Lesley Jones
    Citation: BMC Genomics 2015 16:1079
  34. To safeguard the food supply for the growing human population, it is important to understand and exploit the genetic basis of quantitative traits. Next-generation sequencing technology performs advantageously ...

    Authors: Hongjun Liu, Yongchao Niu, Pedro J. Gonzalez-Portilla, Huangkai Zhou, Liya Wang, Tao Zuo, Cheng Qin, Shuaishuai Tai, Constantin Jansen, Yaou Shen, Haijian Lin, Michael Lee, Doreen Ware, Zhiming Zhang, Thomas Lübberstedt and Guangtang Pan
    Citation: BMC Genomics 2015 16:1078
  35. Kawasaki Disease (KD) can cause potentially life-threatening coronary arteritis in young children, and has a likely infectious etiology. Transcriptome profiling is a powerful approach to investigate gene expre...

    Authors: Anne H. Rowley, Kristine M. Wylie, Kwang-Youn A. Kim, Adam J. Pink, Amy Yang, Rebecca Reindel, Susan C. Baker, Stanford T. Shulman, Jan M. Orenstein, Mark W. Lingen, George M. Weinstock and Todd N. Wylie
    Citation: BMC Genomics 2015 16:1076
  36. Rickettsia species are obligate intracellular Gram-negative pathogenic bacteria and the etiologic agents of diseases such as Rocky Mountain spotted fever (RMSF), Mediterranean spotted ...

    Authors: Casey L. C. Schroeder, Hema P. Narra, Mark Rojas, Abha Sahni, Jignesh Patel, Kamil Khanipov, Thomas G. Wood, Yuriy Fofanov and Sanjeev K. Sahni
    Citation: BMC Genomics 2015 16:1075
  37. Low phytic acid (lpa) crops are potentially eco-friendly alternative to conventional normal phytic acid (PA) crops, improving mineral bioavailability in monogastric animals as well as decreasing phosphate polluti...

    Authors: Neelam R. Redekar, Ruslan M. Biyashev, Roderick V. Jensen, Richard F. Helm, Elizabeth A. Grabau and M. A. Saghai Maroof
    Citation: BMC Genomics 2015 16:1074
  38. The selection of beef cattle for feed efficiency (FE) traits is very important not only for productive and economic efficiency but also for reduced environmental impact of livestock. Considering that FE is mul...

    Authors: Pamela A. Alexandre, Lisette J. A. Kogelman, Miguel H. A. Santana, Danielle Passarelli, Lidia H. Pulz, Paulo Fantinato-Neto, Paulo L. Silva, Paulo R. Leme, Ricardo F. Strefezzi, Luiz L. Coutinho, José B. S. Ferraz, Joanie P. Eler, Haja N. Kadarmideen and Heidge Fukumasu
    Citation: BMC Genomics 2015 16:1073

    The Erratum to this article has been published in BMC Genomics 2016 17:311

  39. Homeostasis of ions and water is important for the maintenance of cellular functions. The regulation of the homeostasis is particularly important in euryhaline fish that migrate between freshwater (FW) and sea...

    Authors: Keng Po Lai, Jing-Woei Li, Je Gu, Ting-Fung Chan, William Ka Fai Tse and Chris Kong Chu Wong
    Citation: BMC Genomics 2015 16:1072
  40. The molecular mechanisms that determine the organism's response to a variety of doses and modalities of stress factors are not well understood.

    Authors: Alexey Moskalev, Svetlana Zhikrivetskaya, George Krasnov, Mikhail Shaposhnikov, Ekaterina Proshkina, Dmitry Borisoglebsky, Anton Danilov, Darya Peregudova, Irina Sharapova, Eugenia Dobrovolskaya, Ilya Solovev, Nadezhda Zemskaya, Lyubov Shilova, Anastasia Snezhkina and Anna Kudryavtseva
    Citation: BMC Genomics 2015 16(Suppl 13):S8

    This article is part of a Supplement: Volume 16 Supplement 13

  41. The statistical thermodynamics based approach provides a promising framework for construction of the genotype-phenotype map in many biological systems. Among important aspects of a good model connecting the DN...

    Authors: Konstantin Kozlov, Vitaly V Gursky, Ivan V Kulakovskiy, Arina Dymova and Maria Samsonova
    Citation: BMC Genomics 2015 16(Suppl 13):S7

    This article is part of a Supplement: Volume 16 Supplement 13

  42. Recently fibroblasts of many mammalian species have been reprogrammed to pluripotent state using overexpression of several transcription factors. This technology allows production of induced pluripotent stem (...

    Authors: Aleksei G Menzorov, Natalia M Matveeva, Marios N Markakis, Venyamin S Fishman, Knud Christensen, Anna A Khabarova, Inna E Pristyazhnyuk, Elena A Kizilova, Susanna Cirera, Razvan Anistoroaei and Oleg L Serov
    Citation: BMC Genomics 2015 16(Suppl 13):S6

    This article is part of a Supplement: Volume 16 Supplement 13

  43. Obesity affects quality of life and life expectancy and is associated with cardiovascular disorders, cancer, diabetes, reproductive disorders in women, prostate diseases in men, and congenital anomalies in chi...

    Authors: Olga V Arkova, Mikhail P Ponomarenko, Dmitry A Rasskazov, Irina A Drachkova, Tatjana V Arshinova, Petr M Ponomarenko, Ludmila K Savinkova and Nikolay A Kolchanov
    Citation: BMC Genomics 2015 16(Suppl 13):S5

    This article is part of a Supplement: Volume 16 Supplement 13

  44. As the evolution of miRNA genes has been found to be one of the important factors in formation of the modern type of man, we performed a comparative analysis of the evolution of miRNA genes in two archaic homi...

    Authors: Konstantin V Gunbin, Dmitry A Afonnikov, Nikolay A Kolchanov, Anatoly P Derevianko and Eugeny I Rogaev
    Citation: BMC Genomics 2015 16(Suppl 13):S4

    This article is part of a Supplement: Volume 16 Supplement 13

  45. Study of the relationship between the structural and functional organization of proteins and their coding genes is necessary for an understanding of the evolution of molecular systems and can provide new knowl...

    Authors: Irina V Medvedeva, Pavel S Demenkov and Vladimir A Ivanisenko
    Citation: BMC Genomics 2015 16(Suppl 13):S2

    This article is part of a Supplement: Volume 16 Supplement 13

  46. The assessment of cell-free circulating DNA fragments, also known as a "liquid biopsy" of the patient's plasma, is an important source for the discovery and subsequent non-invasive monitoring of cancer and oth...

    Authors: Maxim Ivanov, Ancha Baranova, Timothy Butler, Paul Spellman and Vladislav Mileyko
    Citation: BMC Genomics 2015 16(Suppl 13):S1

    This article is part of a Supplement: Volume 16 Supplement 13

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