Skip to main content

Articles

Page 181 of 338

  1. MicroRNAs (miRNAs) have increasingly been found to regulate diseases at a significant level. The interaction of miRNA and diseases is a complex web of multilevel interactions, given the fact that a miRNA regul...

    Authors: Joseph J Nalluri, Bhanu K Kamapantula, Debmalya Barh, Neha Jain, Antaripa Bhattacharya, Sintia Silva de Almeida, Rommel Thiago Juca Ramos, Artur Silva, Vasco Azevedo and Preetam Ghosh
    Citation: BMC Genomics 2015 16(Suppl 5):S12
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  2. Meningitis is the inflammation of the meninges in response to infection or chemical agents. While aseptic meningitis, most frequently caused by enteroviruses, is usually benign with a self-limiting course, bac...

    Authors: Ana Paula Cordeiro, Rosiane Aparecida Silva Pereira, Alex Chapeaurouge, Clarice Semião Coimbra, Jonas Perales, Guilherme Oliveira, Talitah Michel Sanchez Candiani and Roney Santos Coimbra
    Citation: BMC Genomics 2015 16(Suppl 5):S11
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  3. Biological nitrogen fixation, with an emphasis on the legume-rhizobia symbiosis, is a key process for agriculture and the environment, allowing the replacement of nitrogen fertilizers, reducing water pollution...

    Authors: Helton Azevedo, Fabricio Martins Lopes, Paulo Roberto Silla and Mariangela Hungria
    Citation: BMC Genomics 2015 16(Suppl 5):S10
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  4. The bacterium Corynebacterium pseudotuberculosis (Cp) causes caseous lymphadenitis (CLA), mastitis, ulcerative lymphangitis, and oedema in a number of hosts, comprising ruminants, thereby intimidating economic an...

    Authors: Leandro G Radusky, Syed Shah Hassan, Esteban Lanzarotti, Sandeep Tiwari, Syed Babar Jamal, Javed Ali, Amjad Ali, Rafaela Salgado Ferreira, Debmalya Barh, Artur Silva, Adrián G Turjanski and Vasco AC Azevedo
    Citation: BMC Genomics 2015 16(Suppl 5):S9
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  5. The epidermal growth factor receptor (EGFR) is a member of the ErbB family that is involved in a number of processes responsible for cancer development and progression such as angiogenesis, apoptosis, cell pro...

    Authors: Sukriti Goyal, Salma Jamal, Asheesh Shanker and Abhinav Grover
    Citation: BMC Genomics 2015 16(Suppl 5):S8
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  6. Corynebacterium urealyticum is an opportunistic pathogen that normally lives on skin and mucous membranes in humans. This high Gram-positive bacteria can cause acute or encrusted cystitis, encrusted pyelitis, and...

    Authors: Luis Carlos Guimarães, Siomar de Castro Soares, Eva Trost, Jochen Blom, Rommel Thiago Jucá Ramos, Artur Silva, Debmalya Barh and Vasco Azevedo
    Citation: BMC Genomics 2015 16(Suppl 5):S7
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  7. In the context of ancestral gene order reconstruction from extant genomes, there exist two main computational approaches: rearrangement-based, and homology-based methods. The rearrangement-based methods consis...

    Authors: Amandine Perrin, Jean-Stéphane Varré, Samuel Blanquart and Aïda Ouangraoua
    Citation: BMC Genomics 2015 16(Suppl 5):S6
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  8. A fundamental question in neuroscience is how memories are stored and retrieved in the brain. Long-term memory formation requires transcription, translation and epigenetic processes that control gene expressio...

    Authors: Lucia L Peixoto, Mathieu E Wimmer, Shane G Poplawski, Jennifer C Tudor, Charles A Kenworthy, Shichong Liu, Keiko Mizuno, Benjamin A Garcia, Nancy R Zhang, K Peter Giese and Ted Abel
    Citation: BMC Genomics 2015 16(Suppl 5):S5
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  9. Chromatin immunoprecipitation followed by sequencing of protein-bound DNA fragments (ChIP-Seq) is an effective high-throughput methodology for the identification of context specific DNA fragments that are boun...

    Authors: Mukesh Bansal, Geetu Mendiratta, Santosh Anand, Ritu Kushwaha, Ryan Hyunjae Kim, Manju Kustagi, Archana Iyer, Raju SK Chaganti, Andrea Califano and Pavel Sumazin
    Citation: BMC Genomics 2015 16(Suppl 5):S4
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  10. Despite the large increase of transcriptomic studies that look for gene signatures on diseases, there is still a need for integrative approaches that obtain separation of multiple pathological states providing...

    Authors: Sara Aibar, Celia Fontanillo, Conrad Droste, Beatriz Roson-Burgo, Francisco J Campos-Laborie, Jesus M Hernandez-Rivas and Javier De Las Rivas
    Citation: BMC Genomics 2015 16(Suppl 5):S3
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  11. Breast cancer is a genetically heterogeneous type of cancer that belongs to the most prevalent types with a high mortality rate. Treatment and prognosis of breast cancer would profit largely from a correct cla...

    Authors: Mohamed Hamed, Christian Spaniol, Alexander Zapp and Volkhard Helms
    Citation: BMC Genomics 2015 16(Suppl 5):S2
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  12. Ninety-two Streptococcus pneumoniae serotypes have been described so far, but the pneumococcal conjugate vaccine introduced in the Brazilian basic vaccination schedule in 2010 covers only the ten most prevalent i...

    Authors: Dhian RA Camargo, Fabiano S Pais, Ângela C Volpini, Marluce AA Oliveira and Roney S Coimbra
    Citation: BMC Genomics 2015 16(Suppl 5):S1
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  13. Physical and linkage maps are important aids for the assembly of genome sequences, comparative analyses of synteny, and to search for candidate genes by quantitative trait locus analysis. Yellowtail, Seriola quin...

    Authors: Jun-ya Aoki, Wataru Kai, Yumi Kawabata, Akiyuki Ozaki, Kazunori Yoshida, Takashi Koyama, Takashi Sakamoto and Kazuo Araki
    Citation: BMC Genomics 2015 16:406
    Content type: Research article Published on:

  14. In silico models have recently been created in order to predict which genetic variants are more likely to contribute to the risk of a complex trait given their functional characteristics. Howev...

    Authors: Sarah A. Gagliano, Andrew D. Paterson, Michael E. Weale and Jo Knight
    Citation: BMC Genomics 2015 16:405
    Content type: Research article Published on:

  15. Irinotecan (SN38) and oxaliplatin are chemotherapeutic agents used in the treatment of colorectal cancer. However, the frequent development of resistance to these drugs represents a considerable challenge in t...

    Authors: Xue Lin, Jan Stenvang, Mads Heilskov Rasmussen, Shida Zhu, Niels Frank Jensen, Line S Tarpgaard, Guangxia Yang, Kirstine Belling, Claus Lindbjerg Andersen, Jian Li, Lars Bolund and Nils Brünner
    Citation: BMC Genomics 2015 16:404
    Content type: Research article Published on:

  16. Urothelial bladder cancer is a highly heterogeneous disease. Cancer cell lines are useful tools for its study. This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lin...

    Authors: Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau, Benjamín Rodríguez-Santiago, Marinela Méndez-Pertuz, Herbert Auer, Gonzalo Gómez, Herbert Barton Grossman, David G Pisano, Wolfgang A Schulz, Luis A Pérez-Jurado, Alfredo Carrato, Dan Theodorescu, Stephen Chanock, Alfonso Valencia and Francisco X Real
    Citation: BMC Genomics 2015 16:403
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2016 17:829

    The Erratum to this article has been published in BMC Genomics 2015 16:1019

  17. Carbohydrate metabolism is a key feature of vascular plant architecture, and is of particular importance in large woody species, where lignocellulosic biomass is responsible for bearing the bulk of the stem an...

    Authors: Desre Pinard, Eshchar Mizrachi, Charles A Hefer, Anna R Kersting, Fourie Joubert, Carl J Douglas, Shawn D Mansfield and Alexander A Myburg
    Citation: BMC Genomics 2015 16:402
    Content type: Research article Published on:

  18. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) are active in acquired resistance against bacteriophage and plasmids in a number of environments. In the human mouth, CRISPR loci evolve to c...

    Authors: Andrew G Lum, Melissa Ly, Tasha M Santiago-Rodriguez, Mayuri Naidu, Tobias K Boehm and David T Pride
    Citation: BMC Genomics 2015 16:401
    Content type: Research article Published on:

  19. Pseudogymnoascus spp. is a wide group of fungi lineages in the family Pseudorotiaceae including an aggressive pathogen of bats P. destructans. Although several lineages of P. spp. were shown to...

    Authors: Evgeny V Leushkin, Maria D Logacheva, Aleksey A Penin, Roman A Sutormin, Evgeny S Gerasimov, Galina A Kochkina, Natalia E Ivanushkina, Oleg V Vasilenko, Alexey S Kondrashov and Svetlana M Ozerskaya
    Citation: BMC Genomics 2015 16:400
    Content type: Research article Published on:

  20. Improvements in poultry production within the past 50 years have led to increased muscle yield and growth rate, which may be contributing to an increased rate and development of new muscle disorders in chicken...

    Authors: Marie F Mutryn, Erin M Brannick, Weixuan Fu, William R Lee and Behnam Abasht
    Citation: BMC Genomics 2015 16:399
    Content type: Research article Published on:

  21. Tapping panel dryness (TPD) involves in the partial or complete cessation of latex flow thus seriously affect latex production in rubber tree (Hevea brasiliensis). Numerous studies have been conducted to define i...

    Authors: Jin-Ping Liu, Zhi-Qiang Xia, Xiao-Yan Tian and Yi-Jian Li
    Citation: BMC Genomics 2015 16:398
    Content type: Research article Published on:

  22. Whole genome sequences (WGS) have proliferated as sequencing technology continues to improve and costs decline. While many WGS of model or domestic organisms have been produced, a growing number of non-model s...

    Authors: Joshua M Miller, Stephen S Moore, Paul Stothard, Xiaoping Liao and David W Coltman
    Citation: BMC Genomics 2015 16:397
    Content type: Research article Published on:

  24. Leafy spurge (Euphorbia esula) is a perennial weed that is considered glyphosate tolerant, which is partially attributed to escape through establishment of new vegetative shoots from an abundance of underground a...

    Authors: Münevver Doğramacı, Michael E. Foley, David P. Horvath, Alvaro G. Hernandez, Radhika S. Khetani, Christopher J. Fields, Kathleen M. Keating, Mark A. Mikel and James V. Anderson
    Citation: BMC Genomics 2015 16:395
    Content type: Research article Published on:

  25. Chinese bayberry (Myrica rubra Sieb. & Zucc.) is an important subtropical evergreen fruit tree in southern China. Generally dioecious, the female plants are cultivated for fruit and have been studied extensively,...

    Authors: Hui-min Jia, Yun Jiao, Guo-yun Wang, Ying-hui Li, Hui-juan Jia, Hong-xia Wu, Chun-yan Chai, Xiao Dong, Yanping Guo, Liping Zhang, Qi-kang Gao, Wei Chen, Li-juan Song, Eric van de Weg and Zhong-shan Gao
    Citation: BMC Genomics 2015 16:394
    Content type: Research article Published on:

  26. miRNAs are the most abundant class of small non-coding RNAs, and they are involved in post-transcriptional regulations, playing a crucial role in the refinement of genetic programming during plant development....

    Authors: Jayakumar Belli Kullan, Daniela Lopes Paim Pinto, Edoardo Bertolini, Marianna Fasoli, Sara Zenoni, Giovanni Battista Tornielli, Mario Pezzotti, Blake C. Meyers, Lorenzo Farina, Mario Enrico Pè and Erica Mica
    Citation: BMC Genomics 2015 16:393
    Content type: Research article Published on:

  27. Clostridium sordellii can cause severe infections in animals and humans, the latter associated with trauma, toxic shock and often-fatal gynaecological infections. Strains can produce two large ...

    Authors: Edward C. Couchman, Hilary P. Browne, Matt Dunn, Trevor D. Lawley, J. Glenn Songer, Val Hall, Liljana Petrovska, Callum Vidor, Milena Awad, Dena Lyras and Neil F. Fairweather
    Citation: BMC Genomics 2015 16:392
    Content type: Research article Published on:

  28. The study of proteins transferred through semen can provide important information for biological questions such as adaptive evolution, the origin of new species and species richness. The objective of this stud...

    Authors: María Juliana Rodríguez-García, Vilmar Machado and José Galián
    Citation: BMC Genomics 2015 16:391
    Content type: Research article Published on:

  29. CGGBP1 is a repetitive DNA-binding transcription regulator with target sites at CpG-rich sequences such as CGG repeats and Alu-SINEs and L1-LINEs. The role of CGGBP1 as a possible mediator of CpG methylation h...

    Authors: Prasoon Agarwal, Paul Collier, Markus Hsi-Yang Fritz, Vladimir Benes, Helena Jernberg Wiklund, Bengt Westermark and Umashankar Singh
    Citation: BMC Genomics 2015 16:390
    Content type: Research article Published on:

  30. VNTR (Variable Number of Tandem Repeats) composite retrotransposons - SVA (SINE-R-VNTR-Alu), LAVA (LINE-1-Alu-VNTR-Alu), PVA (PTGR2-VNTR-Alu) and FVA (FRAM-VNTR-Alu) - are specific to hominoid primates. Their ass...

    Authors: Iulia Lupan, Paul Bulzu, Octavian Popescu and Annette Damert
    Citation: BMC Genomics 2015 16:389
    Content type: Research article Published on:

  31. Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital-associated infection, but there is growing awareness of the emergence of multidrug-resistant lineages in community settings around t...

    Authors: Eike J Steinig, Patiyan Andersson, Simon R Harris, Derek S Sarovich, Anand Manoharan, Paul Coupland, Matthew TG Holden, Julian Parkhill, Stephen D Bentley, D Ashley Robinson and Steven YC Tong
    Citation: BMC Genomics 2015 16:388
    Content type: Research article Published on:

  32. The demosponge Amphimedon queenslandica is amongst the few early-branching metazoans with an assembled and annotated draft genome, making it an important species in the study of the origin and early evolution of ...

    Authors: Selene L Fernandez-Valverde, Andrew D Calcino and Bernard M Degnan
    Citation: BMC Genomics 2015 16:387
    Content type: Research article Published on:

  33. The mitogen-activated protein kinase (MAPK) cascade consists of three types of reversibly phosphorylated kinases, namely, MAPK, MAPK kinase (MAPKK/MEK), and MAPK kinase kinase (MAPKKK/MEKK), playing important ...

    Authors: Jie Wang, Changtian Pan, Yan Wang, Lei Ye, Jian Wu, Lifei Chen, Tao Zou and Gang Lu
    Citation: BMC Genomics 2015 16:386
    Content type: Research article Published on:

  34. Hypoxia and temperature stress are two major adverse environmental conditions often encountered by fishes. The interaction between hypoxia and temperature stresses has been well documented and oxygen is consid...

    Authors: Yong Long, Junjun Yan, Guili Song, Xiaohui Li, Xixi Li, Qing Li and Zongbin Cui
    Citation: BMC Genomics 2015 16:385
    Content type: Research article Published on:

  35. Previous genome-wide association analyses identified QTL regions in the X chromosome for percentage of normal sperm and scrotal circumference in Brahman and Tropical Composite cattle. These traits are importan...

    Authors: Gregório Miguel Ferreira de Camargo, Laercio R Porto-Neto, Matthew J Kelly, Rowan J Bunch, Sean M McWilliam, Humberto Tonhati, Sigrid A Lehnert, Marina R S Fortes and Stephen S Moore
    Citation: BMC Genomics 2015 16:384
    Content type: Research article Published on:

  36. Arctic Mesorhizobium strain N33 was isolated from nodules of the legume Oxytropis arctobia in Canada’s eastern Arctic. This symbiotic bacterium can grow at temperatures ranging from 0 to 30 °C, fix nitrogen at 10...

    Authors: Abdollah-Fardin Ghobakhlou, Anne Johnston, Linda Harris, Hani Antoun and Serge Laberge
    Citation: BMC Genomics 2015 16:383
    Content type: Research article Published on:

  37. It is now recognized that enzymatic or chemical side-reactions can convert normal metabolites to useless or toxic ones and that a suite of enzymes exists to mitigate such metabolite damage. Examples are the re...

    Authors: Thomas D Niehaus, Svetlana Gerdes, Kelsey Hodge-Hanson, Aleksey Zhukov, Arthur JL Cooper, Mona ElBadawi-Sidhu, Oliver Fiehn, Diana M Downs and Andrew D Hanson
    Citation: BMC Genomics 2015 16:382
    Content type: Research article Published on:

  38. Genome-wide association studies (GWAS) have become a common approach to identifying single nucleotide polymorphisms (SNPs) associated with complex diseases. As complex diseases are caused by the joint effects ...

    Authors: Yi-Ting Wang, Pei-Yuan Sung, Peng-Lin Lin, Ya-Wen Yu and Ren-Hua Chung
    Citation: BMC Genomics 2015 16:381
    Content type: Methodology article Published on:

  39. A major role of REST (repressor element-1 silencing transcription factor) is to inhibit the expression of neuronal genes in neural stem cells and non-neuronal cells by binding to a 21 bp consensus sequence and...

    Authors: Banu Saritas-Yildirim, Christopher P Childers, Christine G Elsik and Elena M Silva
    Citation: BMC Genomics 2015 16:380
    Content type: Research article Published on:

  40. Harvest index (HI), the ratio of grain yield to total biomass, is considered as a measure of biological success in partitioning assimilated photosynthate to the harvestable product. While crop production can b...

    Authors: Xiang Luo, Chaozhi Ma, Yao Yue, Kaining Hu, Yaya Li, Zhiqiang Duan, Ming Wu, Jinxing Tu, Jinxiong Shen, Bin Yi and Tingdong Fu
    Citation: BMC Genomics 2015 16:379
    Content type: Research article Published on:

  41. European eel is a panmictic species, whose decline has been recorded since the last 20 years. Among human-induced environmental factors of decline, the impact of water dams during species migration is question...

    Authors: Tomasz Podgorniak, Massimo Milan, Jose Marti Pujolar, Gregory E Maes, Luca Bargelloni, Eric De Oliveira, Fabien Pierron and Francoise Daverat
    Citation: BMC Genomics 2015 16:378
    Content type: Research article Published on:

  42. The growth and development of skeletal muscle directly impacts the quantity and quality of pork production. Chinese indigenous pig breeds and exotic species vary greatly in terms of muscle production and perfo...

    Authors: Yuqiang Zhao, Ji Li, Huijing Liu, Yu Xi, Ming Xue, Wanghong Liu, Zhenhua Zhuang and Minggang Lei
    Citation: BMC Genomics 2015 16:377
    Content type: Research article Published on:

  43. Species from the Paracoccidioides complex are thermally dimorphic fungi and the causative agents of paracoccidioidomycosis, a deep fungal infection that is the most prevalent systemic mycosis in Latin America and...

    Authors: Marco Aurélio Soares, Roberta Amália de Carvalho Araújo, Marjorie Mendes Marini, Luciana Márcia de Oliveira, Leonardo Gomes de Lima, Viviane de Souza Alves, Maria Sueli Soares Felipe, Marcelo Macedo Brigido, Celia Maria de Almeida Soares, Jose Franco da Silveira, Jeronimo Conceição Ruiz and Patrícia Silva Cisalpino
    Citation: BMC Genomics 2015 16:376
    Content type: Research article Published on:

  44. The number and complexity of repetitive elements varies between species, being in general most represented in those with larger genomes. Combining the flow-sorted chromosome arms approach to genome analysis wi...

    Authors: Ingrid Garbus, José R Romero, Miroslav Valarik, Hana Vanžurová, Miroslava Karafiátová, Mario Cáccamo, Jaroslav Doležel, Gabriela Tranquilli, Marcelo Helguera and Viviana Echenique
    Citation: BMC Genomics 2015 16:375
    Content type: Research article Published on:

  45. In flowering plants it has been shown that de novo genome assemblies of different species and genera show a significant drop in the proportion of alignable sequence. Within a plant species, however, it is assumed...

    Authors: Jan M de Boer, Erwin Datema, Xiaomin Tang, Theo J A Borm, Erin H Bakker, Herman J van Eck, Roeland C H J van Ham, Hans de Jong, Richard G F Visser and Christian W B Bachem
    Citation: BMC Genomics 2015 16:374
    Content type: Research article Published on:

  47. Mycobacterium tuberculosis continues to kill more people than any other bacterium. Although its archetypal host cell is the macrophage, it also enters, and survives within, dendritic cells (DCs...

    Authors: Tom A Mendum, Huihai Wu, Andrzej M Kierzek and Graham R Stewart
    Citation: BMC Genomics 2015 16:372
    Content type: Research article Published on:

  48. Genomic selection (GS) in forestry can substantially reduce the length of breeding cycle and increase gain per unit time through early selection and greater selection intensity, particularly for traits of low ...

    Authors: Omnia Gamal El-Dien, Blaise Ratcliffe, Jaroslav Klápště, Charles Chen, Ilga Porth and Yousry A El-Kassaby
    Citation: BMC Genomics 2015 16:370
    Content type: Research article Published on:

  49. Understanding genetic determinants of a microbial phenotype generally involves creating and comparing isogenic strains differing at the locus of interest, but the naturally existing genomic and phenotypic dive...

    Authors: Yuan Li, Nicholas J Croucher, Claudette M Thompson, Krzysztof Trzciński, William P Hanage and Marc Lipsitch
    Citation: BMC Genomics 2015 16:369
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 3.5
    5-year Journal Impact Factor: 4.1
    Source Normalized Impact per Paper (SNIP): 1.083
    SCImago Journal Rank (SJR): 1.047

    Speed 2023
    Submission to first editorial decision (median days): 21
    Submission to acceptance (median days): 137

    Usage 2023
    Downloads: 7,167,242
    Altmetric mentions: 4,454

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us