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  1. Coix, Sorghum and Zea are closely related plant genera in the subtribe Maydeae. Coix comprises 9–11 species with different ploidy levels (2n = 10, 20, 30, and 40). The exclusively cultivated C. lacryma-jobi L. (2...

    Authors: Zexi Cai, Huijun Liu, Qunyan He, Mingwei Pu, Jian Chen, Jinsheng Lai, Xuexian Li and Weiwei Jin
    Citation: BMC Genomics 2014 15:1025
    Content type: Research article Published on:

  2. Grain aphid (Sitobion avenae F) and pea aphid (Acyrthosiphon pisum) are two agriculturally important pest species, which cause significant yield losses to crop plants each year by inflicting damage both through t...

    Authors: Dahai Wang, Qi Liu, Huw D Jones, Toby Bruce and Lanqin Xia
    Citation: BMC Genomics 2014 15:1023
    Content type: Research article Published on:

  3. Genetic variation in the human population is a key determinant of influenza disease severity. A single nucleotide polymorphism in the antiviral gene IFITM3 was linked to outcomes during the 2009 H1N1 pandemic. To...

    Authors: Adrianus CM Boon, Robert W Williams, David S Sinasac and Richard J Webby
    Citation: BMC Genomics 2014 15:1017
    Content type: Research article Published on:

  4. Genome-wide saturation mutagenesis and subsequent phenotype-driven screening has been central to a comprehensive understanding of complex biological processes in classical model organisms such as flies, nemato...

    Authors: Masahiro Tokunaga, Chikara Kokubu, Yusuke Maeda, Jun Sese, Kyoji Horie, Nakaba Sugimoto, Taroh Kinoshita, Kosuke Yusa and Junji Takeda
    Citation: BMC Genomics 2014 15:1016
    Content type: Research article Published on:

  6. Sphingobium spp. are efficient degraders of a wide range of chlorinated and aromatic hydrocarbons. In particular, strains which harbour the lin pathway genes mediating the degradation of hexachlorocyclohexane (HC...

    Authors: Helianthous Verma, Roshan Kumar, Phoebe Oldach, Naseer Sangwan, Jitendra P Khurana, Jack A Gilbert and Rup Lal
    Citation: BMC Genomics 2014 15:1014
    Content type: Research article Published on:

  7. Structural mutations (SMs) play a major role in cancer development. In some cancers, such as breast and ovarian, DNA double-strand breaks (DSBs) occur more frequently in transcribed regions, while in other can...

    Authors: Krzysztof R Grzeda, Beryl Royer-Bertrand, Koichiro Inaki, Hyunsoo Kim, Axel M Hillmer, Edison T Liu and Jeffrey H Chuang
    Citation: BMC Genomics 2014 15:1013
    Content type: Research article Published on:

  8. Lactation is a key aspect of mammalian evolution for adaptation of various reproductive strategies along different mammalian lineages. Marsupials, such as tammar wallaby, adopted a short gestation and a relati...

    Authors: Vengamanaidu Modepalli, Amit Kumar, Lyn A Hinds, Julie A Sharp, Kevin R Nicholas and Christophe Lefevre
    Citation: BMC Genomics 2014 15:1012
    Content type: Research article Published on:

  9. Chemical mutagenesis screens are useful to identify mutants involved in biological processes of interest. Identifying the mutation from such screens, however, often fails when using methodologies involving tra...

    Authors: Jin Woo Bok, Philipp Wiemann, Graeme S Garvey, Fang Yun Lim, Brian Haas, Jennifer Wortman and Nancy P Keller
    Citation: BMC Genomics 2014 15:1011
    Content type: Research article Published on:

  10. MicroRNAs are a class of short non-coding RNAs derived from either cellular or viral transcripts that act post-transcriptionally to regulate mRNA stability and translation. In recent days, increasing numbers o...

    Authors: Jyotirmoy Das, Soumita Podder and Tapash Chandra Ghosh
    Citation: BMC Genomics 2014 15:1010
    Content type: Research article Published on:

  11. High temperature affects organism growth and metabolic activity. Heat shock transcription factors (Hsfs) are key regulators in heat shock response in eukaryotes and prokaryotes. Under high temperature conditio...

    Authors: Pan-Song Li, Tai-Fei Yu, Guan-Hua He, Ming Chen, Yong-Bin Zhou, Shou-Cheng Chai, Zhao-Shi Xu and You-Zhi Ma
    Citation: BMC Genomics 2014 15:1009
    Content type: Research article Published on:

  12. Microarrays have revolutionized breast cancer (BC) research by enabling studies of gene expression on a transcriptome-wide scale. Recently, RNA-Sequencing (RNA-Seq) has emerged as an alternative for precise re...

    Authors: Debora Fumagalli, Alexis Blanchet-Cohen, David Brown, Christine Desmedt, David Gacquer, Stefan Michiels, Françoise Rothé, Samira Majjaj, Roberto Salgado, Denis Larsimont, Michail Ignatiadis, Marion Maetens, Martine Piccart, Vincent Detours, Christos Sotiriou and Benjamin Haibe-Kains
    Citation: BMC Genomics 2014 15:1008
    Content type: Research article Published on:

  13. Typhoid fever is an infectious disease of global importance that is caused by Salmonella enterica subsp. enterica serovar Typhi (S. Typhi). This disease causes an estimated 200,000 deaths per year and remains a s...

    Authors: Kien-Pong Yap, Han Ming Gan, Cindy Shuan Ju Teh, Lay Ching Chai and Kwai Lin Thong
    Citation: BMC Genomics 2014 15:1007
    Content type: Research article Published on:

  14. Cassava mosaic disease is caused by several distinct geminivirus species, including South African cassava mosaic virus-[South Africa:99] (SACMV). To date, there is limited gene regulation information on viral str...

    Authors: Farhahna Allie, Erica J Pierce, Michal J Okoniewski and Chrissie Rey
    Citation: BMC Genomics 2014 15:1006
    Content type: Research article Published on:

  15. To identify the key elements controlling grain production in maize, it is essential to have an integrated view of the responses to alterations in the main steps of nitrogen assimilation by modification of gene...

    Authors: Nardjis Amiour, Sandrine Imbaud, Gilles Clément, Nicolas Agier, Michel Zivy, Benoît Valot, Thierry Balliau, Isabelle Quilleré, Thérèse Tercé-Laforgue, Céline Dargel-Graffin and Bertrand Hirel
    Citation: BMC Genomics 2014 15:1005
    Content type: Research article Published on:

  16. The identification of genetic markers associated with complex traits that are expensive to record such as feed intake or feed efficiency would allow these traits to be included in selection programs. To identi...

    Authors: Mahdi Saatchi, Jonathan E Beever, Jared E Decker, Dan B Faulkner, Harvey C Freetly, Stephanie L Hansen, Helen Yampara-Iquise, Kristen A Johnson, Stephen D Kachman, Monty S Kerley, JaeWoo Kim, Daniel D Loy, Elisa Marques, Holly L Neibergs, E John Pollak, Robert D Schnabel…
    Citation: BMC Genomics 2014 15:1004
    Content type: Research article Published on:

  18. CRISPR-Cas9 is a revolutionary genome editing technique that allows for efficient and directed alterations of the eukaryotic genome. This relatively new technology has already been used in a large number of ‘l...

    Authors: Charles C Bell, Graham W Magor, Kevin R Gillinder and Andrew C Perkins
    Citation: BMC Genomics 2014 15:1002
    Content type: Methodology article Published on:

  19. Major changes in gene expression occur in the fetal brain to modulate the function of this organ postnatally. Thus, factors can alter the genomics of the fetal brain, predisposing to neurological disorders lat...

    Authors: Maria B Rabaglino, Maureen Keller-Wood and Charles E Wood
    Citation: BMC Genomics 2014 15:1001
    Content type: Research article Published on:

  20. One of the most common goals of hierarchical clustering is finding those branches of a tree that form quantifiably distinct data subtypes. Achieving this goal in a statistically meaningful way requires (a) a m...

    Authors: Guoli Sun and Alexander Krasnitz
    Citation: BMC Genomics 2014 15:1000
    Content type: Methodology article Published on:

  21. The pea aphid Acyrthosiphon pisum has two modes of reproduction: parthenogenetic during the spring and summer and sexual in autumn. This ability to alternate between reproductive modes and the emergence of clonal...

    Authors: Victoria Reingold, Neta Luria, Alain Robichon and Aviv Dombrovsky
    Citation: BMC Genomics 2014 15:999
    Content type: Research article Published on:

  23. DNA methylation (DNAm) levels can be used to predict the chronological age of tissues; however, the characteristics of DNAm age signatures in normal and cancer tissues are not well studied using multiple studies.

    Authors: Jihyun Kim, Kyung Kim, Hyosil Kim, Gyesoon Yoon and KiYoung Lee
    Citation: BMC Genomics 2014 15:997
    Content type: Research article Published on:

  24. Sugarcane smut can cause losses in cane yield and sugar content that range from 30% to total crop failure. Losses tend to increase with the passage of years. Sporisorium scitamineum is the fungus that causes suga...

    Authors: Youxiong Que, Liping Xu, Qibin Wu, Yongfeng Liu, Hui Ling, Yanhong Liu, Yuye Zhang, Jinlong Guo, Yachun Su, Jiebo Chen, Shanshan Wang and Chengguang Zhang
    Citation: BMC Genomics 2014 15:996
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2015 16:244

  25. Wild barley is adapted to highly diverse environments throughout its geographical distribution range. Transcriptome sequencing of differentially adapted wild barley ecotypes from contrasting environments contr...

    Authors: Girma Bedada, Anna Westerbergh, Thomas Müller, Eyal Galkin, Eyal Bdolach, Menachem Moshelion, Eyal Fridman and Karl J Schmid
    Citation: BMC Genomics 2014 15:995
    Content type: Research article Published on:

  26. The TRA/TRD locus contains the genes for V(D)J somatic rearrangement of TRA and TRD chains expressed by αβ and γδ T cells respectively. Previous studies have demonstrated that the bovine TRA/TRD locus contains...

    Authors: Timothy K Connelley, Kathryn Degnan, Cassandra W Longhi and W Ivan Morrison
    Citation: BMC Genomics 2014 15:994
    Content type: Research article Published on:

  27. Nuclear receptors (NRs) are a large superfamily of proteins defined by a DNA-binding domain (DBD) and a ligand-binding domain (LBD). They function as transcriptional regulators to control expression of genes i...

    Authors: Dae-Sik Hwang, Bo-Young Lee, Hui-Su Kim, Min Chul Lee, Do-Hyun Kyung, Ae-Son Om, Jae-Sung Rhee and Jae-Seong Lee
    Citation: BMC Genomics 2014 15:993
    Content type: Research article Published on:

  29. Multidrug- (MDR) and extensively drug resistant (XDR) tuberculosis (TB) presents a challenge to disease control and elimination goals. In Lisbon, Portugal, specific and successful XDR-TB strains have been foun...

    Authors: João Perdigão, Hugo Silva, Diana Machado, Rita Macedo, Fernando Maltez, Carla Silva, Luisa Jordao, Isabel Couto, Kim Mallard, Francesc Coll, Grant A Hill-Cawthorne, Ruth McNerney, Arnab Pain, Taane G Clark, Miguel Viveiros and Isabel Portugal
    Citation: BMC Genomics 2014 15:991
    Content type: Research article Published on:

  32. Chromatin compactness has been considered a major determinant of gene activity and has been associated with specific chromatin modifications in studies on a few individual genetic loci. At the same time, genom...

    Authors: Beatrice Milon, Yezhou Sun, Weizhong Chang, Todd Creasy, Anup Mahurkar, Amol Shetty, Dmitry Nurminsky and Maria Nurminskaya
    Citation: BMC Genomics 2014 15:988
    Content type: Research article Published on:

  33. Arthropod venoms are invaluable sources of bioactive substances with biotechnological application. The limited availability of some venoms, such as those from ants, has restricted the knowledge about the compo...

    Authors: Wafa Bouzid, Marion Verdenaud, Christophe Klopp, Frédéric Ducancel, Céline Noirot and Angélique Vétillard
    Citation: BMC Genomics 2014 15:987
    Content type: Research article Published on:

  34. Exiguobacterium antarcticum strain B7 is a Gram-positive psychrotrophic bacterial species isolated in Antarctica. Although this bacteria has been poorly studied, its genome has already been sequenced. Therefore, ...

    Authors: Hivana PMB Dall’Agnol, Rafael A Baraúna, Pablo HCG de Sá, Rommel TJ Ramos, Felipe Nóbrega, Catarina IP Nunes, Diego A das Graças, Adriana R Carneiro, Daniel M Santos, Adriano MC Pimenta, Marta SP Carepo, Vasco Azevedo, Vivian H Pellizari, Maria PC Schneider and Artur Silva
    Citation: BMC Genomics 2014 15:986
    Content type: Research article Published on:

  36. Panduratin A extracted from Boesenbergia rotunda is a flavonoid reported to possess a range of medicinal indications which include anti-dengue, anti-HIV, anti-cancer, antioxidant and anti-inflammatory properties....

    Authors: Noor Diyana Md-Mustafa, Norzulaani Khalid, Huan Gao, Zhiyu Peng, Mohd Firdaus Alimin, Noraini Bujang, Wong Sher Ming, Yusmin Mohd-Yusuf, Jennifer A Harikrishna and Rofina Yasmin Othman
    Citation: BMC Genomics 2014 15:984
    Content type: Research article Published on:

  37. Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a diverse group of biologically active bacterial molecules. Due to the conserved genomic arrangement of many of the genes involved...

    Authors: Anne-Catrin Letzel, Sacha J Pidot and Christian Hertweck
    Citation: BMC Genomics 2014 15:983
    Content type: Research article Published on:

  38. Glaucoma is characterized by progressive loss of the visual field and death of retinal ganglion cells (RGCs), a process that is mediated, in part, by axonal injury. However, the molecular pathomechanisms linki...

    Authors: Masayuki Yasuda, Yuji Tanaka, Koji M Nishiguchi, Morin Ryu, Satoru Tsuda, Kazuichi Maruyama and Toru Nakazawa
    Citation: BMC Genomics 2014 15:982
    Content type: Research article Published on:

  39. Several individual studies have suggested that autosomal CpG methylation differs by sex both in terms of individual CpG sites and global autosomal CpG methylation. However, these findings have been inconsisten...

    Authors: Nina S McCarthy, Phillip E Melton, Gemma Cadby, Seyhan Yazar, Maria Franchina, Eric K Moses, David A Mackey and Alex W Hewitt
    Citation: BMC Genomics 2014 15:981
    Content type: Research article Published on:

  40. Phytophthora cactorum, a hemibiotrophic oomycete pathogen, can cause destructive diseases on numerous crops worldwide, leading to essential economic losses every year. However, little has been known about its mol...

    Authors: Xiao-Ren Chen, Bo-Yue Zhang, Yu-Ping Xing, Qi-Yuan Li, Yan-Peng Li, Yun-Hui Tong and Jing-You Xu
    Citation: BMC Genomics 2014 15:980
    Content type: Research article Published on:

  41. Many areas critical to agricultural production and research, such as the breeding and trait mapping in plants and livestock, require robust and scalable genotyping platforms. Genotyping-by-sequencing (GBS) is ...

    Authors: Christopher Heffelfinger, Christopher A Fragoso, Maria A Moreno, John D Overton, John P Mottinger, Hongyu Zhao, Joe Tohme and Stephen L Dellaporta
    Citation: BMC Genomics 2014 15:979
    Content type: Methodology article Published on:

  42. Human induced pluripotent stem cells (iPSCs) have a wide range of applications throughout the fields of basic research, disease modeling and drug screening. Epigenetic instable iPSCs with aberrant DNA methylat...

    Authors: Xiaojian Shao, Cuiyun Zhang, Ming-An Sun, Xuemei Lu and Hehuang Xie
    Citation: BMC Genomics 2014 15:978
    Content type: Research article Published on:

  43. Cyanobacteria are an ancient lineage of photosynthetic bacteria from which hundreds of natural products have been described, including many notorious toxins but also potent natural products of interest to the ...

    Authors: Alexandra Calteau, David P Fewer, Amel Latifi, Thérèse Coursin, Thierry Laurent, Jouni Jokela, Cheryl A Kerfeld, Kaarina Sivonen, Jörn Piel and Muriel Gugger
    Citation: BMC Genomics 2014 15:977
    Content type: Research article Published on:

  44. Micro-RNAs (miRNA) are attributed to the systems biological role of a regulatory mechanism of the expression of protein coding genes. Research has identified miRNAs dysregulations in several but distinct patho...

    Authors: Alfred Ultsch and Jörn Lötsch
    Citation: BMC Genomics 2014 15:976
    Content type: Research article Published on:

  45. Sex-determination genes drive the evolution of adjacent chromosomal regions. Sexually antagonistic selection favors the accumulation of inversions that reduce recombination in regions adjacent to the sex-deter...

    Authors: William J Gammerdinger, Matthew A Conte, Enoch A Acquah, Reade B Roberts and Thomas D Kocher
    Citation: BMC Genomics 2014 15:975
    Content type: Research article Published on:

  46. Jatropha curcas, whose seed content is approximately 30–40% oil, is an ideal feedstock for producing biodiesel and bio-jet fuels. However, Jatropha plants have a low number of female flowers, which results in low...

    Authors: Bang-Zhen Pan, Mao-Sheng Chen, Jun Ni and Zeng-Fu Xu
    Citation: BMC Genomics 2014 15:974
    Content type: Research article Published on:

  47. Anaplasma phagocytophilum is a zoonotic and obligate intracellular bacterium transmitted by ticks. In domestic ruminants, it is the causative agent of tick-borne fever, which causes significant economic losses in...

    Authors: Thibaud Dugat, Valentin Loux, Sylvain Marthey, Marco Moroldo, Anne-Claire Lagrée, Henri-Jean Boulouis, Nadia Haddad and Renaud Maillard
    Citation: BMC Genomics 2014 15:973
    Content type: Research article Published on:

  48. While much recent research has expanded our understanding of the molecular interactions between aphids and their host plants, it is lacking for the soybean aphid, Aphis glycines. Since its North American invasion...

    Authors: Raman Bansal, MAR Mian, Omprakash Mittapalli and Andy P Michel
    Citation: BMC Genomics 2014 15:972
    Content type: Research article Published on:

  50. Streptomyces are widespread bacteria that contribute to the terrestrial carbon cycle and produce the majority of clinically useful antibiotics. While interspecific genomic diversity has been investigated among St...

    Authors: James R Doroghazi and Daniel H Buckley
    Citation: BMC Genomics 2014 15:970
    Content type: Research article Published on:

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BMC Genomics

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