Skip to main content

Articles

Page 220 of 338

  1. Isatis indigotica is a widely used herb for the clinical treatment of colds, fever, and influenza in Traditional Chinese Medicine (TCM). Various structural classes of compounds have been identified as effective i...

    Authors: Junfeng Chen, Xin Dong, Qing Li, Xun Zhou, Shouhong Gao, Ruibing Chen, Lianna Sun, Lei Zhang and Wansheng Chen
    Citation: BMC Genomics 2013 14:857
    Content type: Research article Published on:

  2. Wood-feeding insects often work in collaboration with microbial symbionts to degrade lignin biopolymers and release glucose and other fermentable sugars from recalcitrant plant cell wall carbohydrates, includi...

    Authors: Erin D Scully, Kelli Hoover, John E Carlson, Ming Tien and Scott M Geib
    Citation: BMC Genomics 2013 14:850
    Content type: Research article Published on:

  3. Small non-coding RNAs (sRNA) are emerging as major components of the cell’s regulatory network, several possessing their own regulons. A few sRNAs have been reported as being involved in general or toxic-metab...

    Authors: Keerthi P Venkataramanan, Shawn W Jones, Kevin P McCormick, Sridhara G Kunjeti, Matthew T Ralston, Blake C Meyers and Eleftherios T Papoutsakis
    Citation: BMC Genomics 2013 14:849
    Content type: Research article Published on:

  4. Serum concentrations of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) are highly heritable traits that are used clinic...

    Authors: Congying Chen, Bin Yang, Zhijun Zeng, Hui Yang, Chenlong Liu, Jun Ren and Lusheng Huang
    Citation: BMC Genomics 2013 14:848
    Content type: Research article Published on:

  5. The filamentous fungus Aspergillus nidulans has been a tractable model organism for cell biology and genetics for over 60 years. It is among a large number of Aspergilli whose genomes have been sequenced since 20...

    Authors: Christopher Sibthorp, Huihai Wu, Gwendolyn Cowley, Prudence W H Wong, Paulius Palaima, Igor Y Morozov, Gareth D Weedall and Mark X Caddick
    Citation: BMC Genomics 2013 14:847
    Content type: Research article Published on:

  6. Orb-web and cob-web weaving spiders spin dragline silk fibers that are among the strongest materials known. Draglines are primarily composed of MaSp1 and MaSp2, two spidroins (spider fibrous proteins) expresse...

    Authors: Amanda Kelly Lane, Cheryl Y Hayashi, Gregg B Whitworth and Nadia A Ayoub
    Citation: BMC Genomics 2013 14:846
    Content type: Research article Published on:

  7. Porcine fatty acid composition is a key factor for quality and nutritive value of pork. Several QTLs for fatty acid composition have been reported in diverse fat tissues. The results obtained so far seem to po...

    Authors: María Muñoz, M Carmen Rodríguez, Estefânia Alves, Josep María Folch, Noelia Ibañez-Escriche, Luis Silió and Ana Isabel Fernández
    Citation: BMC Genomics 2013 14:845
    Content type: Research article Published on:

  8. Glucocorticoids (GCs) are natural stress induced steroid hormones causing cell cycle arrest and cell death in lymphoid tissues. Therefore they are the central component in the treatment of lymphoid malignancie...

    Authors: Tatsiana Aneichyk, Daniel Bindreither, Christine Mantinger, Daniela Grazio, Katrin Goetsch, Reinhard Kofler and Johannes Rainer
    Citation: BMC Genomics 2013 14:844
    Content type: Research article Published on:

  9. In pigs, adipose tissue is one of the principal organs involved in the regulation of lipid metabolism. It is particularly involved in the overall fatty acid synthesis with consequences in other lipid-target or...

    Authors: Jordi Corominas, Yuliaxis Ramayo-Caldas, Anna Puig-Oliveras, Jordi Estellé, Anna Castelló, Estefania Alves, Ramona N Pena, Maria Ballester and Josep M Folch
    Citation: BMC Genomics 2013 14:843
    Content type: Research article Published on:

  11. Abscisic acid (ABA) can regulate the expressions of many stress-responsive genes in plants. However, in defense responses to pathogens, mounting evidence suggests that ABA plays variable roles. Little informat...

    Authors: Yan Wang, Xiang Tao, Xiao-Mei Tang, Liang Xiao, Jiao-long Sun, Xue-Feng Yan, Dan Li, Hong-Yuan Deng and Xin-Rong Ma
    Citation: BMC Genomics 2013 14:841
    Content type: Research article Published on:

  12. Brassica seeds are important as basic units of plant growth and sources of vegetable oil. Seed development is regulated by many dynamic metabolic processes controlled by complex networks of spatially and temporal...

    Authors: Ram Kumar Basnet, Natalia Moreno-Pachon, Ke Lin, Johan Bucher, Richard G F Visser, Chris Maliepaard and Guusje Bonnema
    Citation: BMC Genomics 2013 14:840
    Content type: Research article Published on:

  13. Dynamics of polyadenylation vs. deadenylation determine the fate of several developmentally regulated genes. Decay of a subset of maternal mRNAs and new transcription define the maternal-to-zygotic transition,...

    Authors: Sarita S Paranjpe, Ulrike G Jacobi, Simon J van Heeringen and Gert Jan C Veenstra
    Citation: BMC Genomics 2013 14:762
    Content type: Research article Published on:

  14. Basic leucine zipper (bZIP) transcription factors are present exclusively in eukaryotes and constitute one of the largest and most diverse transcription factor families. The proteins are responsible for centra...

    Authors: Wenwu Ye, Yang Wang, Suomeng Dong, Brett M Tyler and Yuanchao Wang
    Citation: BMC Genomics 2013 14:839
    Content type: Research article Published on:

  15. Acetic acid is mostly known as a toxic by-product of alcoholic fermentation carried out by Saccharomyces cerevisiae, which it frequently impairs. The more recent finding that acetic acid triggers apoptotic progra...

    Authors: Marlene Sousa, Ana Marta Duarte, Tânia R Fernandes, Susana R Chaves, Andreia Pacheco, Cecília Leão, Manuela Côrte-Real and Maria João Sousa
    Citation: BMC Genomics 2013 14:838
    Content type: Research article Published on:

  16. Hansenula polymorpha DL1 is a methylotrophic yeast, widely used in fundamental studies of methanol metabolism, peroxisome biogenesis and function, and also as a microbial cell factory for production of recombinan...

    Authors: Nikolai V Ravin, Michael A Eldarov, Vitaly V Kadnikov, Alexey V Beletsky, Jessica Schneider, Eugenia S Mardanova, Elena M Smekalova, Maria I Zvereva, Olga A Dontsova, Andrey V Mardanov and Konstantin G Skryabin
    Citation: BMC Genomics 2013 14:837
    Content type: Research article Published on:

  17. Radish (Raphanus sativus L.), is an important root vegetable crop worldwide. Glucosinolates in the fleshy taproot significantly affect the flavor and nutritional quality of radish. However, little is known about ...

    Authors: Yan Wang, Yan Pan, Zhe Liu, Xianwen Zhu, Lulu Zhai, Liang Xu, Rugang Yu, Yiqin Gong and Liwang Liu
    Citation: BMC Genomics 2013 14:836
    Content type: Research article Published on:

  18. The tomato (Solanum lycopersium L.) is the most widely grown vegetable in the world. It was domesticated in Latin America and Italy and Spain are considered secondary centers of diversification. This food crop ha...

    Authors: Giandomenico Corrado, Pietro Piffanelli, Martina Caramante, Mariangela Coppola and Rosa Rao
    Citation: BMC Genomics 2013 14:835
    Content type: Research article Published on:

  19. Chromatin immunoprecipitation combined with massive parallel sequencing (ChIP-seq) is widely used to study protein-chromatin interactions or chromatin modifications at genome-wide level. Sequence reads that ac...

    Authors: Marco-Antonio Mendoza-Parra, Malgorzata Nowicka, Wouter Van Gool and Hinrich Gronemeyer
    Citation: BMC Genomics 2013 14:834
    Content type: Software Published on:

  20. Cytochrome P450 2S1 (CYP2S1) is an orphan P450 with an unknown biological function. Data from our laboratory and others suggest that CYP2S1 may have an important physiological role in modulating the synthesis ...

    Authors: Thushara W Madanayake, Ingrid E Lindquist, Nicholas P Devitt, Joann Mudge and Aaron M Rowland
    Citation: BMC Genomics 2013 14:833
    Content type: Research article Published on:

  21. We introduce Iterative Feature Removal (IFR) as an unbiased approach for selecting features with diagnostic capacity from large data sets. The algorithm is based on recently developed tools in machine learning...

    Authors: Stephen O’Hara, Kun Wang, Richard A Slayden, Alan R Schenkel, Greg Huber, Corey S O’Hern, Mark D Shattuck and Michael Kirby
    Citation: BMC Genomics 2013 14:832
    Content type: Methodology article Published on:

  22. Alzheimer’s disease affects more than 35 million people worldwide but there is no known cure. Age is the strongest risk factor for Alzheimer’s disease but it is not clear how age-related changes impact the dis...

    Authors: Harriet M Jackson, Ileana Soto, Leah C Graham, Gregory W Carter and Gareth R Howell
    Citation: BMC Genomics 2013 14:831
    Content type: Research article Published on:

  23. Cellular differentiation is characterized by the acquisition of specialized structures and functions, cell cycle exit, and global attenuation of the DNA damage response. It is largely unknown how these diverse...

    Authors: Xiangwei Wang, Jeong-Hyeon Choi, Jane Ding, Liqun Yang, Lambert C Ngoka, Eun J Lee, Yunhong Zha, Ling Mao, Bilian Jin, Mingqiang Ren, John Cowell, Shuang Huang, Huidong Shi, Hongjuan Cui and Han-Fei Ding
    Citation: BMC Genomics 2013 14:830
    Content type: Research article Published on:

  24. Xanthomonas fragariae (Xf) is a bacterial strawberry pathogen and an A2 quarantine organism on strawberry planting stock in the EU. It is taxonomically and metabolically distinct within the genus Xanthomonas, and...

    Authors: Joachim Vandroemme, Bart Cottyn, Steve Baeyen, Paul De Vos and Martine Maes
    Citation: BMC Genomics 2013 14:829
    Content type: Research article Published on:

  25. Gene regulatory processes are largely resulting from binding of transcription factors to specific genomic targets. Leucine-responsive Regulatory Protein (Lrp) is a prevalent transcription factor family in prok...

    Authors: Trong Nguyen-Duc, Liesbeth van Oeffelen, Ningning Song, Gholamreza Hassanzadeh-Ghassabeh, Serge Muyldermans, Daniel Charlier and Eveline Peeters
    Citation: BMC Genomics 2013 14:828
    Content type: Research article Published on:

  26. Anthurium andraeanum is one of the most popular tropical flowers. In temperate and cold zones, a much greater risk of cold stress occurs in the supply of Anthurium plants. Unlike the freeze-tolerant model plants,...

    Authors: Dan-Qing Tian, Xiao-Yun Pan, Yong-Ming Yu, Wei-Yong Wang, Fei Zhang, Ya-Ying Ge, Xiao-Lan Shen, Fu-Quan Shen and Xiao-Jing Liu
    Citation: BMC Genomics 2013 14:827
    Content type: Research article Published on:

  27. Cell-specific gene expression is controlled by epigenetic modifications and transcription factor binding. While genome-wide maps for these protein-DNA interactions have become widely available, quantitative co...

    Authors: Gabriele Schweikert, Botond Cseke, Thomas Clouaire, Adrian Bird and Guido Sanguinetti
    Citation: BMC Genomics 2013 14:826
    Content type: Methodology article Published on:

  28. Psoriasis is a chronic autoimmune disease in which T cells have a predominant role in initiating and perpetuating the chronic inflammation in skin. However, the mechanisms that regulate T cell activation in ps...

    Authors: Nuria Palau, Antonio Julià, Carlos Ferrándiz, Lluís Puig, Eduardo Fonseca, Emilia Fernández, María López-Lasanta, Raül Tortosa and Sara Marsal
    Citation: BMC Genomics 2013 14:825
    Content type: Research article Published on:

  29. SUMOylation, as part of the epigenetic regulation of transcription, has been intensively studied in lower eukaryotes that contain only a single SUMO protein; however, the functions of SUMOylation during mammal...

    Authors: Pei-Ching Chang, Chia-Yang Cheng, Mel Campbell, Yi-Cheng Yang, Hung-Wei Hsu, Ting-Yu Chang, Chia-Han Chu, Yi-Wei Lee, Chiu-Lien Hung, Shi-Mei Lai, Clifford G Tepper, Wen-Ping Hsieh, Hsei-Wei Wang, Chuan-Yi Tang, Wen-Ching Wang and Hsing-Jien Kung
    Citation: BMC Genomics 2013 14:824
    Content type: Research article Published on:

  30. Pear (Pyrus spp) is an important fruit species worldwide; however, its genetics and genomic information is limited. Combining the Solexa/Illumina RNA-seq high-throughput sequencing approach (RNA-seq) with Digital...

    Authors: Min Xie, Ying Huang, Yanping Zhang, Xin Wang, Hua Yang, Oliver Yu, Wenhao Dai and Congbing Fang
    Citation: BMC Genomics 2013 14:823
    Content type: Research article Published on:

  31. Serratia sp. ATCC 39006 (S39006) is a Gram-negative enterobacterium that is virulent in plant and animal models. It produces a red-pigmented trypyrrole secondary metabolite, prodigiosin (Pig), and a carbapenem an...

    Authors: Nabil M Wilf, Adam J Reid, Joshua P Ramsay, Neil R Williamson, Nicholas J Croucher, Laurent Gatto, Svenja S Hester, David Goulding, Lars Barquist, Kathryn S Lilley, Robert A Kingsley, Gordon Dougan and George PC Salmond
    Citation: BMC Genomics 2013 14:822
    Content type: Research article Published on:

  32. Durum wheat often faces water scarcity and high temperatures, two events that usually occur simultaneously in the fields. Here we report on the stress responsive strategy of two durum wheat cultivars, characte...

    Authors: Alessio Aprile, Lenka Havlickova, Riccardo Panna, Caterina Marè, Grazia M Borrelli, Daniela Marone, Carla Perrotta, Patrizia Rampino, Luigi De Bellis, Vladislav Curn, Anna M Mastrangelo, Fulvia Rizza and Luigi Cattivelli
    Citation: BMC Genomics 2013 14:821
    Content type: Research article Published on:

  33. As the largest low-latitude permafrost region, the Tibetan Plateau (TP) is an important part of the earth’s terrestrial ecosystem and one of the most vulnerable areas to climate change and human activities. Ho...

    Authors: Xiangyu Guan, Jinfeng Wang, Hui Zhao, Jianjun Wang, Ximing Luo, Fei Liu and Fangqing Zhao
    Citation: BMC Genomics 2013 14:820
    Content type: Research article Published on:

  34. Infectious cDNA clones are a prerequisite for directed genetic manipulation of RNA viruses. Here, a strategy to facilitate manipulation and rescue of classical swine fever viruses (CSFVs) from full-length cDNA...

    Authors: Thomas Bruun Rasmussen, Peter Christian Risager, Ulrik Fahnøe, Martin Barfred Friis, Graham J Belsham, Dirk Höper, Ilona Reimann and Martin Beer
    Citation: BMC Genomics 2013 14:819
    Content type: Research article Published on:

  35. RNA-seq has spurred important gene fusion discoveries in a number of different cancers, including lung, prostate, breast, brain, thyroid and bladder carcinomas. Gene fusion discovery can potentially lead to th...

    Authors: Nameeta Shah, Michael Lankerovich, Hwahyung Lee, Jae-Geun Yoon, Brett Schroeder and Greg Foltz
    Citation: BMC Genomics 2013 14:818
    Content type: Research article Published on:

  36. Warmer seawater as a result of climate change may impose environmental challenges for Atlantic salmon aquaculture in its southernmost geographic range. Seawater temperatures above optimal level for growth may ...

    Authors: Pål A Olsvik, Vibeke Vikeså, Kai K Lie and Ernst M Hevrøy
    Citation: BMC Genomics 2013 14:817
    Content type: Research article Published on:

  37. The genetic make-up of humans and other mammals (such as mice) affects their resistance to influenza virus infection. Considering the complexity and moral issues associated with experiments on human subjects, ...

    Authors: Suying Bao, Xueya Zhou, Liangcai Zhang, Jie Zhou, Kelvin Kai-Wang To, Binbin Wang, Liqiu Wang, Xuegong Zhang and You-Qiang Song
    Citation: BMC Genomics 2013 14:816
    Content type: Research article Published on:

  38. Diapause or developmental arrest, is one of the major adaptations that allows mites and insects to survive unfavorable conditions. Diapause evokes a number of physiological, morphological and molecular modific...

    Authors: Astrid Bryon, Nicky Wybouw, Wannes Dermauw, Luc Tirry and Thomas Van Leeuwen
    Citation: BMC Genomics 2013 14:815
    Content type: Research article Published on:

  39. Freezing provokes severe yield losses to different fall-sown annual legumes. Understanding the molecular bases of freezing tolerance is of great interest for breeding programs. Medicago truncatula Gaertn. is an a...

    Authors: Nadim Tayeh, Nasser Bahrman, Hélène Sellier, Aurélie Bluteau, Christelle Blassiau, Joëlle Fourment, Arnaud Bellec, Frédéric Debellé, Isabelle Lejeune-Hénaut and Bruno Delbreil
    Citation: BMC Genomics 2013 14:814
    Content type: Research article Published on:

  40. Nucleosomes facilitate the packaging of the eukaryotic genome and modulate the access of regulators to DNA. A detailed description of the nucleosomal organization under different transcriptional programmes is ...

    Authors: Ignacio Soriano, Luis Quintales and Francisco Antequera
    Citation: BMC Genomics 2013 14:813
    Content type: Research article Published on:

  41. It is generally accepted that gene order in eukaryotes is nonrandom, with adjacent genes often sharing expression patterns across tissues, and that this organization may be important for gene regulation. Here ...

    Authors: Alan F Rubin and Phil Green
    Citation: BMC Genomics 2013 14:812
    Content type: Research article Published on:

  42. The silver-lipped pearl oyster, Pinctada maxima, is an important tropical aquaculture species extensively farmed for the highly sought "South Sea" pearls. Traditional breeding programs have been initiated for thi...

    Authors: David B Jones, Dean R Jerry, Mehar S Khatkar, Herman W Raadsma and Kyall R Zenger
    Citation: BMC Genomics 2013 14:810
    Content type: Research article Published on:

  43. Stem cells located in the centre of the shoot apical meristem are required for the repetitive formation of new organs such as leaves, branches and flowers. In Arabidopsis thaliana, the ZWILLE/PINHEAD/AGO10 (ZLL) ...

    Authors: Matthew R Tucker, Farshad Roodbarkelari, Elisabeth Truernit, Nikolai M Adamski, Annika Hinze, Barbara Lohmüller, Tobias Würschum and Thomas Laux
    Citation: BMC Genomics 2013 14:809
    Content type: Research article Published on:

  44. Cell growth rate reflects an organism’s physiological state and largely relies on the ability of gene expression to respond to the environment. The relationship between cellular growth rate and gene expression...

    Authors: Yuki Matsumoto, Yoshie Murakami, Saburo Tsuru, Bei-Wen Ying and Tetsuya Yomo
    Citation: BMC Genomics 2013 14:808
    Content type: Research article Published on:

  45. Fungal pathogens cause devastating losses in economically important cereal crops by utilising pathogen proteins to infect host plants. Secreted pathogen proteins are referred to as effectors and have thus far ...

    Authors: Jana Sperschneider, Donald M Gardiner, Jennifer M Taylor, James K Hane, Karam B Singh and John M Manners
    Citation: BMC Genomics 2013 14:807
    Content type: Research article Published on:

  46. The phytohormone auxin mediates a stunning array of plant development through the functions of AUXIN RESPONSE FACTORs (ARFs), which belong to transcription factors and are present as a protein family comprisin...

    Authors: Qian Zhu, Baoyan Li, Shuyuan Mu, Bing Han, Runzhi Cui, Manyu Xu, Zhenzhen You and Hansong Dong
    Citation: BMC Genomics 2013 14:806
    Content type: Research article Published on:

  48. We conducted genomic sequencing to identify Epstein Barr Virus (EBV) genomes in 2 human peripheral blood B lymphocytes that underwent spontaneous immortalization promoted by mycoplasma infections in culture, u...

    Authors: Haiyan Lei, Tianwei Li, Guo-Chiuan Hung, Bingjie Li, Shien Tsai and Shyh-Ching Lo
    Citation: BMC Genomics 2013 14:804
    Content type: Research article Published on:

  49. Lycium chinense is well known in traditional Chinese herbal medicine for its medicinal value and composition, which have been widely studied for decades. However, further research on Lycium chinense is limited du...

    Authors: Shicheng Zhao, Pham Anh Tuan, Xiaohua Li, Yeon Bok Kim, HyeRan Kim, Chun Geon Park, Jingli Yang, Cheng Hao Li and Sang Un Park
    Citation: BMC Genomics 2013 14:802
    Content type: Research article Published on:

  50. The bacterium Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the most frequent causes of foodborne outbreaks of gastroenteritis. Between 2005–2008 a series of S. Typhimurium outbreaks occurred...

    Authors: Jane Hawkey, David J Edwards, Karolina Dimovski, Lester Hiley, Helen Billman-Jacobe, Geoff Hogg and Kathryn E Holt
    Citation: BMC Genomics 2013 14:800
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 3.5
    5-year Journal Impact Factor: 4.1
    Source Normalized Impact per Paper (SNIP): 1.083
    SCImago Journal Rank (SJR): 1.047

    Speed 2023
    Submission to first editorial decision (median days): 21
    Submission to acceptance (median days): 137

    Usage 2023
    Downloads: 7,167,242
    Altmetric mentions: 4,454

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us