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  1. Septoria tritici blotch (STB), caused by Zymoseptoria tritici (Z. tritici), is an important biotic threat to durum wheat in the entire Mediterranean Basin. Although most durum wheat cultivars are susceptible to Z...

    Authors: Sahbi Ferjaoui, Lamia Aouini, Rim B. Slimane, Karim Ammar, Suzanne Dreisigacker, Henk J. Schouten, Suraj Sapkota, Bochra A. Bahri, Sarrah Ben M’Barek, Richard G. F. Visser, Gert H. J. Kema and Sonia Hamza
    Citation: BMC Genomics 2022 23:372
    Content type: Research Published on:

  2. Cucurbita pepo is highly susceptible to Zucchini yellow mosaic virus (ZYMV) and the resistance found in several wild species cannot be considered as complete or broad-spectrum resistance. In this study, a source ...

    Authors: C. G. Amoroso, G. Andolfo, C. Capuozzo, A. Di Donato, C. Martinez, L. Tomassoli and M. R. Ercolano
    Citation: BMC Genomics 2022 23:371
    Content type: Research Published on:

  3. Authors: Yulin Bai, Mei Wang, Ji Zhao, Huaqiang Bai, Xinyi Zhang, Jiaying Wang, Qiaozhen Ke, Ang Qu, Fei Pu, Weiqiang Zheng, Tao Zhou and Peng Xu
    Citation: BMC Genomics 2022 23:370
    Content type: Correction Published on:

    The original article was published in BMC Genomics 2022 23:206

  4. Drought stress is the most limiting factor for plant growth and crop production worldwide. As a major cereal crop, wheat is susceptible to drought. Thus, discovering and utilizing drought-tolerant gene resourc...

    Authors: Fengkun Lu, Wenjing Duan, Yue Cui, Junwei Zhang, Dong Zhu, Ming Zhang and Yueming Yan
    Citation: BMC Genomics 2022 23:369
    Content type: Research Published on:

  5. Numerous genome-wide association studies have been performed to understand the influence of genetic variation on type 2 diabetes etiology. Many identified risk variants are located in non-coding and intergenic...

    Authors: Gerard A. Bouland, Joline W. J. Beulens, Joey Nap, Arno R. van der Slik, Arnaud Zaldumbide, Leen M. ’t Hart and Roderick C. Slieker
    Citation: BMC Genomics 2022 23:368
    Content type: Research Published on:

  6. Baculoviruses act as effective biological control agents against the invasive pest Hyphantria cunea Drury. In this study, two Chinese Hyphantria cunea nucleopolyhedrovirus (HycuNPV) isolates, HycuNPV-BJ and HycuN...

    Authors: Xiaowei Peng, Wenying Zhang, Chengfeng Lei, Shuifa Min, Jia Hu, Qinghua Wang and Xiulian Sun
    Citation: BMC Genomics 2022 23:367
    Content type: Research Published on:

  7. Pichia pastoris (Komagataella phaffii) is a model organism widely used for the recombinant expression of eukaryotic proteins, and it can metabolize methanol as its sole carbon and energy source. Methanol is oxidi...

    Authors: Yi-fan Yu, Jiashuo Yang, Fengguang Zhao, Ying Lin and Shuangyan Han
    Citation: BMC Genomics 2022 23:366
    Content type: Research Published on:

  8. Escherichia coli carrying clinically important antimicrobial resistances [i.e., against extended-spectrum-beta-lactamases (ESBL)] are of high concern for human health and are increasingly detected worldwide. Worr...

    Authors: Katharina Juraschek, Janina Malekzadah, Burkhard Malorny, Annemarie Käsbohrer, Stefan Schwarz, Diana Meemken and Jens Andre Hammerl
    Citation: BMC Genomics 2022 23:365
    Content type: Research Published on:

  9. Multi-omics data can provide a stereoscopic view to explore potential causal variations and genes, as well as underlying genetic mechanisms of complex traits. However, for many non-mammalian species, including...

    Authors: Weiwei Fu, Rui Wang, Naiyi Xu, Jinxin Wang, Ran Li, Hojjat Asadollahpour Nanaei, Qinghua Nie, Xin Zhao, Jianlin Han, Ning Yang and Yu Jiang
    Citation: BMC Genomics 2022 23:364
    Content type: Database Published on:

  10. Cervical artificial insemination (AI) with frozen-thawed semen results in unacceptably low pregnancy rates internationally. The exception is in Norway, where vaginal deposition of frozen-thawed semen to a natu...

    Authors: Laura Abril-Parreño, Kieran G. Meade, Anette Kristine Krogenæs, Xavier Druart, Paul Cormican and Sean Fair
    Citation: BMC Genomics 2022 23:363
    Content type: Research Published on:

  11. Multiple sclerosis (MS) is a debilitating immune-mediated disease of the central nervous system that affects over 2 million people worldwide, resulting in a heavy burden to families and entire communities. Und...

    Authors: Andi Liu, Astrid M. Manuel, Yulin Dai and Zhongming Zhao
    Citation: BMC Genomics 2022 23(Suppl 4):362
    Content type: Research Published on:

    This article is part of a Supplement: Volume 23 Supplement 4

  12. Accurate bacteria genome de novo assembly is fundamental to understand the evolution and pathogenesis of new bacteria species. The advent and popularity of Third-Generation Sequencing (TGS) enables assembly of...

    Authors: Fengyuan Huang, Li Xiao, Min Gao, Ethan J. Vallely, Kevin Dybvig, T. Prescott Atkinson, Ken B. Waites and Zechen Chong
    Citation: BMC Genomics 2022 23(Suppl 4):361
    Content type: Software Published on:

    This article is part of a Supplement: Volume 23 Supplement 4

  13. Genome-wide association studies (GWAS) have uncovered thousands of genetic variants that are associated with complex human traits and diseases. miRNAs are single-stranded non-coding RNAs. In particular, geneti...

    Authors: Melinda Song, Jiaqi Yu, Binze Li, Julian Dong, Jeslyn Gao, Lulu Shang, Xiang Zhou and Yongsheng Bai
    Citation: BMC Genomics 2022 23(Suppl 4):360
    Content type: Research Published on:

    This article is part of a Supplement: Volume 23 Supplement 4

  14. Single-cell DNA sequencing is getting indispensable in the study of cell-specific cancer genomics. The performance of computational tools that tackle single-cell genome aberrations may be nevertheless underval...

    Authors: Xikang Feng and Lingxi Chen
    Citation: BMC Genomics 2022 23(Suppl 4):359
    Content type: Software Published on:

    This article is part of a Supplement: Volume 23 Supplement 4

  15. Yak estrus is a seasonal phenomenon, probably involving epigenetic regulation of synthesis and secretion of sex hormones as well as growth and development of follicles. N6-methyladenosine (m6A) is the most common...

    Authors: Shaoke Guo, Xingdong Wang, Mengli Cao, Xiaoyun Wu, Lin Xiong, Pengjia Bao, Min Chu, Chunnian Liang, Ping Yan, Jie Pei and Xian Guo
    Citation: BMC Genomics 2022 23:358
    Content type: Research Published on:

  16. The DoG (Delay of Germination1) family plays a key regulatory role in seed dormancy and germination. However, to date, there is no complete genomic overview of the DoG gene family of any economically valuable cro...

    Authors: Zhang Zhijun, Yu Peiyao, Huang Bing, Ma Ruifang, Kunnummal Kurungara Vinod and Muthusamy Ramakrishnan
    Citation: BMC Genomics 2022 23:357
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:128

  18. Alternative splicing (AS) increases the diversity of transcriptome and could fine-tune the function of genes, so that understanding the regulation of AS is vital. AS could be regulated by many different cis-regul...

    Authors: Cheng-Kai Shiau, Jia-Hsin Huang, Yu-Ting Liu and Huai-Kuang Tsai
    Citation: BMC Genomics 2022 22(Suppl 5):919
    Content type: Research Published on:

    This article is part of a Supplement: Volume 22 Supplement 5

  19. The mechanisms through which Mycobacterium tuberculosis evades immune surveillance during tuberculosis (TB) infection remain complex. Previous studies have found that Mycobacteria can manipulate the miRNAs of hos...

    Authors: Xuehua Zhan, Wenqi Yuan, Yueyong Zhou, Rong Ma and Zhaohui Ge
    Citation: BMC Genomics 2022 23:355
    Content type: Research Published on:

  20. We combined an unsupervised learning methodology for analyzing mitogenome sequences with maximum likelihood (ML) phylogenetics to make detailed inferences about the evolution and diversification of mitochondri...

    Authors: Dana Kristjansson, Jon Bohlin, Truc Trung Nguyen, Astanand Jugessur and Theodore G. Schurr
    Citation: BMC Genomics 2022 23:354
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2022 23:459

  21. The cotton leafworm, Spodoptera littoralis, is a highly polyphagous pest of many cultivated plants and crops in Africa and Europe. The genome of this pest will help us to further understand the molecular mechanis...

    Authors: Chao Wu, Lei Zhang, Bo Liu, Bojia Gao, Cong Huang, Ji Zhang, Minghui Jin, Hanyue Wang, Yan Peng, Annabel Rice, Esmat Hegazi, Kenneth Wilson, Pengjun Xu and Yutao Xiao
    Citation: BMC Genomics 2022 23:353
    Content type: Research Published on:

  23. Immune status in the tumor microenvironment is an important determinant of cancer progression and patient prognosis. Although a higher immune activity is often associated with a better prognosis, this trend is...

    Authors: Hitoshi Matsuo, Takashi Kamatani, Yu Hamba, Keith A. Boroevich and Tatsuhiko Tsunoda
    Citation: BMC Genomics 2022 23:351
    Content type: Research Published on:

  24. Lung cancer is the leading cause of cancer death in both men and women. The most common lung cancer subtype is non-small cell lung carcinoma (NSCLC) comprising about 85% of all cases. NSCLC can be further divi...

    Authors: Yuqing Hang, Josh Burns, Benjamin T. Shealy, Rini Pauly, Stephen P. Ficklin and Frank A. Feltus
    Citation: BMC Genomics 2022 23:350
    Content type: Research Published on:

  25. Real-time quantitative PCR is a widely used method for gene expression analyses in various organisms. Its accuracy mainly relies on the correct selection of reference genes. Any experimental plan involving rea...

    Authors: Federica Salatiello, Marco Gerdol, Alberto Pallavicini, Annamaria Locascio and Maria Sirakov
    Citation: BMC Genomics 2022 23:349
    Content type: Research Published on:

  26. CRISPR/Cas9-based genome-editing systems have been used to efficiently engineer livestock species with precise genetic alterations intended for biomedical and agricultural applications. Previously, we have suc...

    Authors: Shiwei Zhou, Peter Kalds, Qi Luo, Kexin Sun, Xiaoe Zhao, Yawei Gao, Bei Cai, Shuhong Huang, Qifang Kou, Bjoern Petersen, Yulin Chen, Baohua Ma and Xiaolong Wang
    Citation: BMC Genomics 2022 23:348
    Content type: Research Published on:

  27. Prenatal exposure to ethanol can cause fetal alcohol spectrum disorder (FASD), a prevalent, preventable pediatric disorder. Identifying genetic risk alleles for FASD is challenging since time, dose, and freque...

    Authors: Tatiana V. Morozova, Vijay Shankar, Rebecca A. MacPherson, Trudy F. C. Mackay and Robert R. H. Anholt
    Citation: BMC Genomics 2022 23:347
    Content type: Research article Published on:

  28. The tomato (Solanum lycopersicum L.) is an economically valuable crop grown worldwide. Because the use of sterile males reduces the cost of F1 seed production, the innovation of male sterility is of great signifi...

    Authors: Huihui Bao, Yumei Ding, Fei Yang, Jie Zhang, Junjun Xie, Chongyan Zhao, Kanghua Du, Yawen Zeng, Kai Zhao, Zuosen Li and Zhengan Yang
    Citation: BMC Genomics 2022 23(Suppl 1):346
    Content type: Research Published on:

    This article is part of a Supplement: Volume 23 Supplement 1

  29. Pan-cancer studies have disclosed many commonalities and differences in mutations, copy number variations, and gene expression alterations among cancers. Some of these features are significantly associated wit...

    Authors: Po-Wen Wang, Yi-Hsun Su, Po-Hao Chou, Ming-Yueh Huang and Ting-Wen Chen
    Citation: BMC Genomics 2022 22(Suppl 5):918
    Content type: Research Published on:

    This article is part of a Supplement: Volume 22 Supplement 5

  30. Lung airway epithelial cells are part of innate immunity and the frontline of defense against bacterial infections. During infection, airway epithelial cells secrete proinflammatory mediators that participate ...

    Authors: Emel Sen-Kilic, Annalisa B. Huckaby, F. Heath Damron and Mariette Barbier
    Citation: BMC Genomics 2022 23:345
    Content type: Research Published on:

  31. The gaur (Bos gaurus) is the largest extant wild bovine species, native to South and Southeast Asia, with unique traits, and is listed as vulnerable by the International Union for Conservation of Nature (IUCN).

    Authors: Wai Yee Low, Benjamin D. Rosen, Yan Ren, Derek M. Bickhart, Thu-Hien To, Fergal J. Martin, Konstantinos Billis, Tad S. Sonstegard, Shawn T. Sullivan, Stefan Hiendleder, John L. Williams, Michael P. Heaton and Timothy P. L. Smith
    Citation: BMC Genomics 2022 23:344
    Content type: Research Published on:

  32. The sustainable development of rice production is facing severe threats by a variety of pathogens, such as necrotrophic Rhizoctonia solani and hemibiotrophic Xanthomonas oryzae pv. oryzae (Xoo). Mining and applyi...

    Authors: Aijun Wang, Li Ma, Xinyue Shu, Yuqi Jiang, Juan Liang and Aiping Zheng
    Citation: BMC Genomics 2022 23:343
    Content type: Research Published on:

  33. The growth and development of skeletal muscle are regulated by protein-coding genes and non-coding RNA. Circular RNA (circRNA) is a type of non-coding RNA involved in a variety of biological processes, especia...

    Authors: Qiuxia Lei, Xin Hu, Haixia Han, Jie Wang, Wei Liu, Yan Zhou, Dingguo Cao, Fuwei Li and Jie Liu
    Citation: BMC Genomics 2022 23:342
    Content type: Research Published on:

  34. Receptor interacting serine/threonine kinase 2 (RIP2), ubiquitous in many tissue/cell types, is the key regulator of immune and inflammatory responses for many diseases, including avian pathogenic E. coli (APEC),...

    Authors: Hongyan Sun, Yexin Yang, Yuxuan Cao, Huan Li, Lujiang Qu and Susan J. Lamont
    Citation: BMC Genomics 2022 23:341
    Content type: Research Published on:

  35. Molluscs remain one significantly under-represented taxa amongst available genomic resources, despite being the second-largest animal phylum and the recent advances in genomes sequencing technologies and genom...

    Authors: Ana Corrochano-Fraile, Andrew Davie, Stefano Carboni and Michaël Bekaert
    Citation: BMC Genomics 2022 23:340
    Content type: Research article Published on:

  36. Allotetraploid oilseed rape (Brassica napus L.) is an important worldwide oil-producing crop. The origin of rapeseed is still undetermined due to the lack of wild resources. Despite certain genetic architecture a...

    Authors: Hongfang Liu, Wei Zhao, Wei Hua and Jing Liu
    Citation: BMC Genomics 2022 23:339
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:716

  37. Gram-negative bacteria are important pathogens in cattle, causing severe infectious diseases, including mastitis. Lipopolysaccharides (LPS) are components of the outer membrane of Gram-negative bacteria and cr...

    Authors: Yahui Gao, Jianbin Li, Gaozhan Cai, Yujiao Wang, Wenjing Yang, Yanqin Li, Xiuxin Zhao, Rongling Li, Yundong Gao, Wenbin Tuo, Ransom L. Baldwin VI, Cong-jun Li, Lingzhao Fang and George E. Liu
    Citation: BMC Genomics 2022 23:338
    Content type: Research Published on:

  38. The cohesin complex is essential for proper chromosome structure and gene expression. Defects in cohesin subunits and regulators cause changes in cohesin complex dynamics and thereby alter three-dimensional ge...

    Authors: Megan Justice, Audra F. Bryan, Juanita C. Limas, Jeanette Gowen Cook and Jill M. Dowen
    Citation: BMC Genomics 2022 23:337
    Content type: Research Published on:

  39. Drought has become the major abiotic stress that causes losses in rice yields and consequently is one of the main environmental factors threatening food security. Long non-coding RNA (lncRNA) is known to play ...

    Authors: Xinsen Yang, Caiyue Liu, Xiaoling Niu, Liu Wang, Laiyi Li, Qianhua Yuan and Xinwu Pei
    Citation: BMC Genomics 2022 23:336
    Content type: Research Published on:

  40. Human granulocytic anaplasmosis is a tick-borne zoonotic disease caused by Anaplasma phagocytophilum. Coinfections with A. phagocytophilum and other tick-borne pathogens are reported frequently, whereas the relat...

    Authors: Ran Duan, Dongyue Lv, Rong Fan, Guoming Fu, Hui Mu, Jinxiao Xi, Xinmin Lu, Hua Chun, Jun Hua, Zhaokai He, Shuai Qin, Yanyan Huang, Meng Xiao, Jinchuan Yang, Huaiqi Jing and Xin Wang
    Citation: BMC Genomics 2022 23:335
    Content type: Research Published on:

  41. Osmanthus fragrans is an evergreen plant with high ornamental and economic values. However, they are easily injured by salt stress, which severely limits their use in high salinity areas. The trihelix transcripti...

    Authors: Meilin Zhu, Jing Bin, Huifen Ding, Duo Pan, Qingyin Tian, Xiulian Yang, Lianggui Wang and Yuanzheng Yue
    Citation: BMC Genomics 2022 23:334
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2022 23:384

  42. Poleroviruses, such as turnip yellows virus (TuYV), are plant viruses strictly transmitted by aphids in a persistent and circulative manner. Acquisition of either virus particles or plant material altered by v...

    Authors: Aurélie Marmonier, Amandine Velt, Claire Villeroy, Camille Rustenholz, Quentin Chesnais and Véronique Brault
    Citation: BMC Genomics 2022 23:333
    Content type: Research Published on:

  43. Oculocutaneous albinism (OCA) is a group of heterogeneous genetic diseases characterized by a reduction or complete lack of pigmentation in the hair, skin, and eyes. It is associated with reduced visual acuity...

    Authors: Yuanyuan Xiao, Cong Zhou, Hanbing Xie, Shuang Huang, Jing Wang and Shanling Liu
    Citation: BMC Genomics 2022 23:332
    Content type: Research Published on:

  44. Genetic progress for fertility and reproduction traits in dairy cattle has been limited due to the low heritability of most indicator traits. Moreover, most of the quantitative trait loci (QTL) and candidate g...

    Authors: Shi-Yi Chen, Flavio S. Schenkel, Ana L. P. Melo, Hinayah R. Oliveira, Victor B. Pedrosa, Andre C. Araujo, Melkaye G. Melka and Luiz F. Brito
    Citation: BMC Genomics 2022 23:331
    Content type: Research Published on:

  45. Chicken provides humans with a large amount of animal protein every year, in which skeletal muscle plays a leading role. The embryonic skeletal muscle development determines the number of muscle fibers and wil...

    Authors: Pengfei Wu, Kaizhi Zhou, Jin Zhang, Xuanze Ling, Xinchao Zhang, Li Zhang, Peifeng Li, Qingyu Wei, Tao Zhang, Xinglong Wang and Genxi Zhang
    Citation: BMC Genomics 2022 23:330
    Content type: Research Published on:

  46. Auxin responsive factor (ARF) family is one of core components in auxin signalling pathway, which governs diverse developmental processes and stress responses. Blueberry is an economically important berry-bear...

    Authors: Xuyan Li, Xiaoyi Zhang, Tianran Shi, Min Chen, Chengguo Jia, Jingying Wang, Zhixia Hou, Junyou Han and Shaomin Bian
    Citation: BMC Genomics 2022 23:329
    Content type: Research Published on:

  49. Most crop seeds are F1 hybrids. Seed providers and plant breeders must be confident that the seed supplied to growers is of known, and uniform, genetic makeup. This requires maintenance of pure genotypes of th...

    Authors: Seongmin Hong, Su Ryun Choi, Jihyeong Kim, Young-Min Jeong, Ju-Sang Kim, Chun-Hee Ahn, Suk-Yoon Kwon, Yong Pyo Lim, Ah-Young Shin and Yong-Min Kim
    Citation: BMC Genomics 2022 23:326
    Content type: Research Published on:

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BMC Genomics

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