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  1. The consensus on how to choose a reference gene for serum or plasma miRNA expression qPCR studies has not been reached and none of the potential candidates have yet been convincingly validated. We proposed a n...

    Authors: Konrad Pagacz, Przemyslaw Kucharski, Urszula Smyczynska, Szymon Grabia, Dipanjan Chowdhury and Wojciech Fendler
    Citation: BMC Genomics 2020 21:111
  2. Transcription has a substantial genetic control and genetic dissection of gene expression could help us understand the genetic architecture of complex phenotypes such as meat quality in cattle. The objectives ...

    Authors: Joel D. Leal-Gutiérrez, Mauricio A. Elzo and Raluca G. Mateescu
    Citation: BMC Genomics 2020 21:104
  3. Luman is a member of CREB3 (cAMP responsive element-binding) subfamily of the basic leucine-zipper (bZIP) transcription factors. It may play an important regulatory role during the decidualization process sinc...

    Authors: Fan Zhao, Huan Liu, Nan Wang, Lijun Yu, Aihua Wang, Yanglei Yi and Yaping Jin
    Citation: BMC Genomics 2020 21:103
  4. Neutrophils are the first effectors of inflammatory response triggered by mastitis infection, and are important defense cells against pathogenic Escherichia coli (E. coli). DNA methylation, as a critical epigenet...

    Authors: Zhihua Ju, Qiang Jiang, Jinpeng Wang, Xiuge Wang, Chunhong Yang, Yan Sun, Yaran Zhang, Changfa Wang, Yaping Gao, Xiaochao Wei, Minghai Hou and Jinming Huang
    Citation: BMC Genomics 2020 21:102
  5. Rhodnius prolixus has become a model for revealing the molecular bases of insect sensory biology due to the publication of its genome and its well-characterized behavioural repertoire. Gene expression modulation ...

    Authors: Jose Manuel Latorre-Estivalis, Marcos Sterkel, Sheila Ons and Marcelo Gustavo Lorenzo
    Citation: BMC Genomics 2020 21:101
  6. Sustainability challenges are currently hampering an increase in salmon production. Using sterile salmon can solve problems with precocious puberty and genetic introgression from farmed escapees to wild popula...

    Authors: Lene Kleppe, Rolf Brudvik Edvardsen, Tomasz Furmanek, Eva Andersson, Kai Ove Skaftnesmo, Frida Thyri Segafredo and Anna Wargelius
    Citation: BMC Genomics 2020 21:99
  7. Broomcorn millet is a drought-tolerant cereal that is widely cultivated in the semiarid regions of Asia, Europe, and other continents; however, the mechanisms underlying its drought-tolerance are poorly unders...

    Authors: Zhongying Shan, Yanmiao Jiang, Haiquan Li, Jinjie Guo, Ming Dong, Jianan Zhang and Guoqing Liu
    Citation: BMC Genomics 2020 21:96
  8. Three-dimensional spatial organization of chromosomes is defined by highly self-interacting regions 0.1–1 Mb in size termed Topological Associating Domains (TADs). Genetic factors that explain dynamic variatio...

    Authors: Omar Shanta, Amina Noor and Jonathan Sebat
    Citation: BMC Genomics 2020 21:95
  9. PLINK is probably the most used program for analyzing SNP genotypes and runs of homozygosity (ROH), both in human and in animal populations. The last decade, ROH analyses have become the state-of-the-art metho...

    Authors: R. Meyermans, W. Gorssen, N. Buys and S. Janssens
    Citation: BMC Genomics 2020 21:94
  10. Whiteflies are a threat to cassava (Manihot esculenta), an important staple food in many tropical/subtropical regions. Understanding the molecular mechanisms regulating cassava’s responses against this pest is cr...

    Authors: Maria L. Irigoyen, Danielle C. Garceau, Adriana Bohorquez-Chaux, Luis Augusto Becerra Lopez-Lavalle, Laura Perez-Fons, Paul D. Fraser and Linda L. Walling
    Citation: BMC Genomics 2020 21:93
  11. Aldrichina grahami (Diptera: Calliphoridae) is a forensically important fly, which has been widely applied to practical legal investigations. Unlike other necrophagous flies, A. grahami exhibits cold tolerance wh...

    Authors: Zhuoying Liu, Han Han, Fanming Meng, Yangshuai Jiang and Jifeng Cai
    Citation: BMC Genomics 2020 21:92
  12. Plant NADPH oxidase (NOX), also known as respiratory burst oxidase homolog (rboh), encoded by the rboh gene, is a key enzyme in the reactive oxygen species (ROS) metabolic network. It catalyzes the formation of t...

    Authors: Wei Wang, Dongdong Chen, Dan Liu, Yingying Cheng, Xiaopei Zhang, Lirong Song, Mengjiao Hu, Jie Dong and Fafu Shen
    Citation: BMC Genomics 2020 21:91
  13. Truffles are symbiotic fungi that develop underground in association with plant roots, forming ectomycorrhizae. They are primarily known for the organoleptic qualities of their hypogeous fruiting bodies. Prima...

    Authors: Federico Vita, Beatrice Giuntoli, Edoardo Bertolini, Cosimo Taiti, Elettra Marone, Chiara D’Ambrosio, Emanuela Trovato, Danilo Sciarrone, Mariosimone Zoccali, Raffaella Balestrini, Andrea Scaloni, Luigi Mondello, Stefano Mancuso, Massimo Alessio and Amedeo Alpi
    Citation: BMC Genomics 2020 21:90
  14. Copy Number Variations (CNVs) are gain or loss of DNA segments that are known to play a role in shaping a wide range of phenotypes. In this study, we used two dairy cattle populations, Holstein Friesian and Je...

    Authors: Young-Lim Lee, Mirte Bosse, Erik Mullaart, Martien A. M. Groenen, Roel F. Veerkamp and Aniek C. Bouwman
    Citation: BMC Genomics 2020 21:89
  15. Branch points (BPs) map within short motifs upstream of acceptor splice sites (3’ss) and are essential for splicing of pre-mature mRNA. Several BP-dedicated bioinformatics tools, including HSF, SVM-BPfinder, B...

    Authors: Raphaël Leman, Hélène Tubeuf, Sabine Raad, Isabelle Tournier, Céline Derambure, Raphaël Lanos, Pascaline Gaildrat, Gaia Castelain, Julie Hauchard, Audrey Killian, Stéphanie Baert-Desurmont, Angelina Legros, Nicolas Goardon, Céline Quesnelle, Agathe Ricou, Laurent Castera…
    Citation: BMC Genomics 2020 21:86
  16. Next generation sequencing (NGS) has become a universal practice in modern molecular biology. As the throughput of sequencing experiments increases, the preparation of conventional multiplexed libraries become...

    Authors: Jennifer Chiniquy, Megan E. Garber, Aindrila Mukhopadhyay and Nathan J. Hillson
    Citation: BMC Genomics 2020 21:85
  17. Environmental variation in the amount of resources available to populations challenge individuals to optimize the allocation of those resources to key fitness functions. This coordination of resource allocatio...

    Authors: E. Ng’oma, P. A. Williams-Simon, A. Rahman and E. G. King
    Citation: BMC Genomics 2020 21:84
  18. Following the publication of this article [1], it was noted that due to a typesetting error the figure legends were paired incorrectly.

    Authors: Everlyn Kamau, John W. Oketch, Zaydah R. de Laurent, My V. T. Phan, Charles N. Agoti, D. James Nokes and Matthew Cotten
    Citation: BMC Genomics 2020 21:83

    The original article was published in BMC Genomics 2020 21:5

  19. Following the publication of this article [1], the authors reported that the captions of Figs. 2 and 3 were published in the incorrect order, whereby they mismatch with their corresponding images. The figures ...

    Authors: Sivasubramanian Rajarammohan, Kumar Paritosh, Deepak Pental and Jagreet Kaur
    Citation: BMC Genomics 2020 21:82

    The original article was published in BMC Genomics 2019 20:1036

  20. Zanthoxylum armatum (Z. armatum) is a highly economically important tree that presents a special numbing taste. However, the underlying regulatory mechanism of the numbing taste remains poorly understood. Thus, t...

    Authors: Wen-Kai Hui, Fei-Yan Zhao, Jing-Yan Wang, Xiao-Yang Chen, Jue-Wei Li, Yu Zhong, Hong-Yun Li, Jun-Xing Zheng, Liang-Zhen Zhang, Qing-Min Que, Ai-Min Wu and Wei Gong
    Citation: BMC Genomics 2020 21:81
  21. Mixed infections of Mycobacterium tuberculosis and antibiotic heteroresistance continue to complicate tuberculosis (TB) diagnosis and treatment. Detection of mixed infections has been limited to molecular genotyp...

    Authors: Christine Anyansi, Arlin Keo, Bruce J. Walker, Timothy J. Straub, Abigail L. Manson, Ashlee M. Earl and Thomas Abeel
    Citation: BMC Genomics 2020 21:80
  22. Contamination of reagents and cross contamination across samples is a long-recognized issue in molecular biology laboratories. While often innocuous, contamination can lead to inaccurate results. Cantalupo et al.

    Authors: Sara R. Selitsky, David Marron, Daniel Hollern, Lisle E. Mose, Katherine A. Hoadley, Corbin Jones, Joel S. Parker, Dirk P. Dittmer and Charles M. Perou
    Citation: BMC Genomics 2020 21:79
  23. Paspalum notatum exhibits both sexual and apomictic cytotypes and, thus, is considered a good model for studies of apomixis because it facilitates comparative approaches. In this work, transcriptome sequencing wa...

    Authors: Fernanda A. de Oliveira, Bianca B. Z. Vigna, Carla C. da Silva, Alessandra P. Fávero, Frederico P. de Matta, Ana L. S. Azevedo and Anete P. de Souza
    Citation: BMC Genomics 2020 21:78
  24. This study used a genome-wide screen of gene expression to better understand the metabolic and functional differences between commercially valuable intramuscular fat (IMF) and commercially wasteful subcutaneou...

    Authors: Nicholas J. Hudson, Antonio Reverter, William J. Griffiths, Eylan Yutuc, Yuqin Wang, Angela Jeanes, Sean McWilliam, David W. Pethick and Paul L. Greenwood
    Citation: BMC Genomics 2020 21:77
  25. Duckweeds (Lemnaceae) are aquatic plants distributed all over the world. The chloroplast genome, as an efficient solar-powered reactor, is an invaluable resource to study biodiversity and to carry foreign genes. ...

    Authors: Yating Zhang, Dong An, Changsheng Li, Zhixuan Zhao and Wenqin Wang
    Citation: BMC Genomics 2020 21:76
  26. High-throughput RNA sequencing (RNA-seq) has evolved as an important analytical tool in molecular biology. Although the utility and importance of this technique have grown, uncertainties regarding the proper a...

    Authors: Xiaohong Li, Nigel G. F. Cooper, Timothy E. O’Toole and Eric C. Rouchka
    Citation: BMC Genomics 2020 21:75
  27. Spermatogenesis is an intricate process regulated by a finely organized network. The orange-spotted grouper (Epinephelus coioides) is a protogynous hermaphroditic fish, but the regulatory mechanism of its spermat...

    Authors: Xi Wu, Yang Yang, Chaoyue Zhong, Yin Guo, Shuisheng Li, Haoran Lin and Xiaochun Liu
    Citation: BMC Genomics 2020 21:73
  28. Calcium-dependent protein kinase (CPK) is one of the main Ca2+ combined protein kinase that play significant roles in plant growth, development and response to multiple stresses. Despite an important member of th...

    Authors: Man Zhang, Yanhui Liu, Qing He, Mengnan Chai, Youmei Huang, Fangqian Chen, Xiaomei Wang, Yeqiang Liu, Hanyang Cai and Yuan Qin
    Citation: BMC Genomics 2020 21:72
  29. Most aphids exhibit wing polyphenism in which wingless and winged morphs produce depending on the population density and host plant quality. Although the influence of environmental factors on wing polyphenism ...

    Authors: Yinjun Fan, Xiuxia Li, Abd Allah A. H. Mohammed, Ying Liu and Xiwu Gao
    Citation: BMC Genomics 2020 21:71
  30. Mycoplasma bovis is an important etiologic agent of bovine mycoplasmosis affecting cattle production and animal welfare. In the past in Israel, M. bovis has been most frequently associated with bovine respiratory...

    Authors: Yael Yair, Ilya Borovok, Inna Mikula, Rama Falk, Larry K. Fox, Uri Gophna and Inna Lysnyansky
    Citation: BMC Genomics 2020 21:70
  31. Members of the AT-HOOK MOTIF CONTAINING NUCLEAR LOCALIZED (AHL) family are involved in various plant biological processes via protein-DNA and protein-protein interaction. However, no the systematic identification...

    Authors: Lanjie Zhao, Youjun Lü, Wei Chen, Jinbo Yao, Yan Li, Qiulin Li, Jingwen Pan, Shengtao Fang, Jie Sun and Yongshan Zhang
    Citation: BMC Genomics 2020 21:69
  32. Global climate change is predicted to force the bathymetric migrations of shallow-water marine invertebrates. Hydrostatic pressure is proposed to be one of the major environmental factors limiting the vertical...

    Authors: Linying Liang, Jiawei Chen, Yanan Li and Haibin Zhang
    Citation: BMC Genomics 2020 21:68
  33. Gene targeting by homology-directed repair (HDR) can precisely edit the genome and is a versatile tool for biomedical research. However, the efficiency of HDR-based modification is still low in many model orga...

    Authors: Haipeng Bai, Lijun Liu, Ke An, Xiaochan Lu, Michael Harrison, Yanqiu Zhao, Ruibin Yan, Zhijie Lu, Song Li, Shuo Lin, Fang Liang and Wei Qin
    Citation: BMC Genomics 2020 21:67
  34. Houseflies (Musca domestica L.) live in intimate association with numerous microorganisms and is a vector of human pathogens. In temperate areas, houseflies will overwinter in environments constructed by humans a...

    Authors: Simon Bahrndorff, Aritz Ruiz-González, Nadieh de Jonge, Jeppe Lund Nielsen, Henrik Skovgård and Cino Pertoldi
    Citation: BMC Genomics 2020 21:66
  35. Alternative splicing (AS) may generate multiple mRNA splicing isoforms from a single mRNA precursor using different splicing sites, leading to enhanced diversity of transcripts and proteins. AS has been implic...

    Authors: Yeyun Li, Xiaozeng Mi, Shiqi Zhao, Junyan Zhu, Rui Guo, Xiaobo Xia, Lu Liu, Shengrui Liu and Chaoling Wei
    Citation: BMC Genomics 2020 21:65
  36. The advent of Next Generation Sequencing has allowed transcriptomes to be profiled with unprecedented accuracy, but the high costs of full-length mRNA sequencing have posed a limit on the accessibility and sca...

    Authors: Gabriel Sholder, Thomas A. Lanz, Robert Moccia, Jie Quan, Estel Aparicio-Prat, Robert Stanton and Hualin S. Xi
    Citation: BMC Genomics 2020 21:64
  37. As a major threat to the oyster industry, Pacific Oyster Mortality Syndrome (POMS) is a polymicrobial disease affecting the main oyster species farmed across the world. POMS affects oyster juveniles and became...

    Authors: Julien de Lorgeril, Bruno Petton, Aude Lucasson, Valérie Perez, Pierre-Louis Stenger, Lionel Dégremont, Caroline Montagnani, Jean-Michel Escoubas, Philippe Haffner, Jean-François Allienne, Marc Leroy, Franck Lagarde, Jérémie Vidal-Dupiol, Yannick Gueguen and Guillaume Mitta
    Citation: BMC Genomics 2020 21:63
  38. The APETALA2/ethylene responsive factor (AP2/ERF) superfamily members are transcription factors that regulate diverse developmental processes and stress responses in plants. They have been identified in many p...

    Authors: Shuting Zhang, Chen Zhu, Yumeng Lyu, Yan Chen, Zihao Zhang, Zhongxiong Lai and Yuling Lin
    Citation: BMC Genomics 2020 21:62
  39. Structural variations (SVs) have been reported to play an important role in genetic diversity and trait regulation. Many computer algorithms detecting SVs have recently been developed, but the use of multiple ...

    Authors: Yueyuan Liu, Mingyue Zhang, Jieying Sun, Wenjing Chang, Manyi Sun, Shaoling Zhang and Jun Wu
    Citation: BMC Genomics 2020 21:61
  40. Lactoferrampin (LFampin), Lactoferricin (LFcin), and LFchimera are three well-known antimicrobial peptides derived from Lactoferrin and proposed as alternatives for antibiotics. Although the intracellular acti...

    Authors: Zana Pirkhezranian, Mojtaba Tahmoorespur, Xavier Daura, Hassan Monhemi and Mohammad Hadi Sekhavati
    Citation: BMC Genomics 2020 21:60
  41. Reproductive capacity can be altered by challenges experienced during critical periods of development, including fetal development and early neonatal life. Gossypol is a polyphenolic compound, commonly found i...

    Authors: Helder Louvandini, Patricia S. Corrêa, Rocío Amorín, Lihe Liu, Egon H. Ieda, Carolina R. Jimenez, Siu M. Tsai, Concepta M. McManus and Francisco Peñagaricano
    Citation: BMC Genomics 2020 21:59
  42. Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study, we aim to explore the phenotyp...

    Authors: Jiaping Wang, Yu Liu, Guangxian Zhao, Jianyi Gao, Junlian Liu, Xiaorui Wu, Chong Xu and Yongzhi Li
    Citation: BMC Genomics 2020 21:57
  43. Shotgun metagenomic sequencing reveals the potential in microbial communities. However, lower-cost 16S ribosomal RNA (rRNA) gene sequencing provides taxonomic, not functional, observations. To remedy this, we ...

    Authors: Nicole R. Narayan, Thomas Weinmaier, Emilio J. Laserna-Mendieta, Marcus J. Claesson, Fergus Shanahan, Karim Dabbagh, Shoko Iwai and Todd Z. DeSantis
    Citation: BMC Genomics 2020 21:56

    The Correction to this article has been published in BMC Genomics 2020 21:105

  44. Following the publication of this article [1], the authors reported that the captions of Figs. 3 and 4 were published in the incorrect order, whereby they mismatch with their corresponding images.

    Authors: Robert Bücking, Murray P. Cox, Georgi Hudjashov, Lauri Saag, Herawati Sudoyo and Mark Stoneking
    Citation: BMC Genomics 2020 21:55

    The original article was published in BMC Genomics 2019 20:1017

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