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  1. Cubozoans (box jellyfish) are cnidarians that have evolved a number of distinguishing features. Many cubozoans have a particularly potent sting, effected by stinging structures called nematocysts; cubozoans ha...

    Authors: Cheryl Lewis Ames, Joseph F. Ryan, Alexandra E. Bely, Paulyn Cartwright and Allen G. Collins
    Citation: BMC Genomics 2016 17:650

    The Erratum to this article has been published in BMC Genomics 2016 17:980

  2. MicroRNAs (miRNA) are varied in length, under 25 nucleotides, single-stranded noncoding RNA that regulate post-transcriptional gene expression via translational repression or mRNA degradation. Elevated levels ...

    Authors: Erik M. Koenig, Craig Fisher, Hugues Bernard, Francis S. Wolenski, Joseph Gerrein, Mary Carsillo, Matt Gallacher, Aimy Tse, Rachel Peters, Aaron Smith, Alexa Meehan, Stephen Tirrell and Patrick Kirby
    Citation: BMC Genomics 2016 17:649
  3. Zearalenone (ZEA) is a secondary metabolite produced by Fusarium species. ZEA was proved to exert a wide range of unwanted side effects, but its mechanism of action, particularly at duodenum levels, remains un...

    Authors: Cornelia Braicu, Roxana Cojocneanu-Petric, Ancuta Jurj, Diana Gulei, Ionelia Taranu, Alexandru Mihail Gras, Daniela Eliza Marin and Ioana Berindan-Neagoe
    Citation: BMC Genomics 2016 17:646
  4. Epstein-Barr virus (EBV) establishes lifelong infections in its human host. The virus is associated with a broad range of malignancies of lymphoid and epithelial origin, including Burkitt’s lymphoma, post-tran...

    Authors: Marjolein J. G. Hooykaas, Elisabeth Kruse, Emmanuel J. H. J. Wiertz and Robert Jan Lebbink
    Citation: BMC Genomics 2016 17:644
  5. Building up of pathway-/disease-relevant signatures provides a persuasive tool for understanding the functional relevance of gene alterations and gene network associations in multifactorial human diseases. Ova...

    Authors: Martin Svoboda, Anastasia Meshcheryakova, Georg Heinze, Markus Jaritz, Dietmar Pils, Dan Cacsire Castillo-Tong, Gudrun Hager, Theresia Thalhammer, Erika Jensen-Jarolim, Peter Birner, Ioana Braicu, Jalid Sehouli, Sandrina Lambrechts, Ignace Vergote, Sven Mahner, Philip Zimmermann…
    Citation: BMC Genomics 2016 17:643
  6. Mass spectrometry-based shotgun proteomics experiments rely on accurate matching of experimental spectra against a database of protein sequences. Existing computational analysis methods are limited in the size...

    Authors: Sandip Chatterjee, Gregory S. Stupp, Sung Kyu Robin Park, Jean-Christophe Ducom, John R. Yates III, Andrew I. Su and Dennis W. Wolan
    Citation: BMC Genomics 2016 17:642
  7. Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically important viral diseases affecting swine industry worldwide. Despite routine farm vaccination, effective control strategies ...

    Authors: Md Aminul Islam, Christine Große-Brinkhaus, Maren Julia Pröll, Muhammad Jasim Uddin, Sharmin Aqter Rony, Dawit Tesfaye, Ernst Tholen, Michael Hölker, Karl Schellander and Christiane Neuhoff
    Citation: BMC Genomics 2016 17:641
  8. A combined supplement of vitamins B9 and B12 was reported to increase milk and milk component yields of dairy cows without effect on feed intake. The present study was undertaken to verify whether this supplem...

    Authors: Bazoumana Ouattara, Nathalie Bissonnette, Melissa Duplessis and Christiane L. Girard
    Citation: BMC Genomics 2016 17:640
  9. The selection of suitable internal control genes is crucial for proper interpretation of real-time PCR data. Here we outline a strategy to identify housekeeping genes that could serve as suitable internal cont...

    Authors: Tatiana M. Tilli, Cláudio da Silva Castro, Jack A. Tuszynski and Nicolas Carels
    Citation: BMC Genomics 2016 17:639
  10. ChIP-seq provides a wealth of information on the approximate location of DNA-binding proteins genome-wide. It is known that the targeted motifs in most cases can be found at the peak centers. A high resolution...

    Authors: Gergely Nagy, Erik Czipa, László Steiner, Tibor Nagy, Sándor Pongor, László Nagy and Endre Barta
    Citation: BMC Genomics 2016 17:637
  11. The AP2/ERF transcription factor is one of the most important gene families in plants, which plays the vital role in regulating plant growth and development as well as in response to diverse stresses. Although...

    Authors: Licao Cui, Kewei Feng, Mengxing Wang, Meng Wang, Pingchuan Deng, Weining Song and Xiaojun Nie
    Citation: BMC Genomics 2016 17:636
  12. An estimated 15,000 children and adolescents under the age of 19 years are diagnosed with leukemia, lymphoma and other tumors in the USA every year. All children and adolescent acute leukemia patients will und...

    Authors: Seesandra V. Rajagopala, Shibu Yooseph, Derek M. Harkins, Kelvin J. Moncera, Keri B. Zabokrtsky, Manolito G. Torralba, Andrey Tovchigrechko, Sarah K. Highlander, Rembert Pieper, Leonard Sender and Karen E. Nelson
    Citation: BMC Genomics 2016 17:635
  13. The bottlenose dolphin (Tursiops truncatus) is a mammal that belongs to the Cetartiodactyla and have lived in marine ecosystems for nearly 60 millions years. Despite its popularity, our knowledge about its adapti...

    Authors: Giovanna Linguiti, Rachele Antonacci, Gianluca Tasco, Francesco Grande, Rita Casadio, Serafina Massari, Vito Castelli, Arianna Consiglio, Marie-Paule Lefranc and Salvatrice Ciccarese
    Citation: BMC Genomics 2016 17:634

    The Erratum to this article has been published in BMC Genomics 2016 17:778

  14. Aspergillus westerdijkiae produces ochratoxin A (OTA) in Aspergillus section Circumdati. It is responsible for the contamination of agricultural crops, fruits, and food commodities, as...

    Authors: Xiaolong Han, Alolika Chakrabortti, Jindong Zhu, Zhao-Xun Liang and Jinming Li
    Citation: BMC Genomics 2016 17:633
  15. Chromatin immunoprecipitation followed by massively parallel DNA sequencing (ChIP-seq) or microarray hybridization (ChIP-chip) has been widely used to determine the genomic occupation of transcription factors ...

    Authors: Chia-Chun Yang, Erik H. Andrews, Min-Hsuan Chen, Wan-Yu Wang, Jeremy J. W. Chen, Mark Gerstein, Chun-Chi Liu and Chao Cheng
    Citation: BMC Genomics 2016 17:632
  16. Alternative splicing events that result in the production of multiple gene isoforms reveals important molecular mechanisms. Gene isoforms are often differentially expressed across organs and tissues, developme...

    Authors: In Seok Yang, Hyeonju Son, Sora Kim and Sangwoo Kim
    Citation: BMC Genomics 2016 17:631

    The Erratum to this article has been published in BMC Genomics 2016 17:828

  17. Differential RNA-Seq (dRNA-Seq) is a recently developed method of performing primary transcriptome analyses that allows for the genome-wide mapping of transcriptional start sites (TSSs) and the identification ...

    Authors: Julia Babski, Karina A. Haas, Daniela Näther-Schindler, Friedhelm Pfeiffer, Konrad U. Förstner, Matthias Hammelmann, Rolf Hilker, Anke Becker, Cynthia M. Sharma, Anita Marchfelder and Jörg Soppa
    Citation: BMC Genomics 2016 17:629
  18. The continuous and non-synchronous nature of postnatal male germ-cell development has impeded stage-specific resolution of molecular events of mammalian meiotic prophase in the testis. Here the juvenile onset ...

    Authors: Robyn L. Ball, Yasuhiro Fujiwara, Fengyun Sun, Jianjun Hu, Matthew A. Hibbs, Mary Ann Handel and Gregory W. Carter
    Citation: BMC Genomics 2016 17:628
  19. Pedunculate oak (Quercus robur L.), an important forest tree in temperate ecosystems, displays an endogenous rhythmic growth pattern, characterized by alternating shoot and root growth flushes paralleled by oscil...

    Authors: Hazel R. Maboreke, Lasse Feldhahn, Markus Bönn, Mika T. Tarkka, Francois Buscot, Sylvie Herrmann, Ralph Menzel and Liliane Ruess
    Citation: BMC Genomics 2016 17:627
  20. To increase the Zn level in shoots, AtHMA4 was ectopically expressed in tomato under the constitutive CaMV 35S promoter. However, the Zn concentration in the shoots of transgenic plants failed to increase at all ...

    Authors: Maria Kendziorek, Maria Klimecka, Anna Barabasz, Sören Borg, Justyna Rudzka, Paweł Szczęsny and Danuta Maria Antosiewicz
    Citation: BMC Genomics 2016 17:625
  21. Plant genomes are populated by different types of repetitive elements including transposable elements (TEs) and simple sequence repeats (SSRs) that can have a strong impact on genome size and dynamic as well a...

    Authors: Ophélie Jouffroy, Surya Saha, Lukas Mueller, Hadi Quesneville and Florian Maumus
    Citation: BMC Genomics 2016 17:624
  22. Leucine-rich repeat receptor-like kinases (LRR-RLKs) represent the largest subfamily of plant RLKs. The functions of most LRR-RLKs have remained undiscovered, and a few that have been experimentally characteri...

    Authors: Diogo M. Magalhães, Larissa L. S. Scholte, Nicholas V. Silva, Guilherme C. Oliveira, Cyril Zipfel, Marco A. Takita and Alessandra A. De Souza
    Citation: BMC Genomics 2016 17:623
  23. Genome-wide surveys have detected cis-acting quantitative trait loci altering levels of RNA transcripts (RNA-eQTLs) by associating SNV alleles to transcript levels. However, the sensitivity and specificity of det...

    Authors: Seungeun Yeo, Colin A. Hodgkinson, Zhifeng Zhou, Jeesun Jung, Ming Leung, Qiaoping Yuan and David Goldman
    Citation: BMC Genomics 2016 17:620
  24. Olfaction is a versatile sensory mechanism for detecting thousands of volatile odorants. Although molecular basis of odorant signaling is relatively well understood considerable gaps remain in the complete cha...

    Authors: Tsviya Olender, Ifat Keydar, Jayant M. Pinto, Pavlo Tatarskyy, Anna Alkelai, Ming-Shan Chien, Simon Fishilevich, Diego Restrepo, Hiroaki Matsunami, Yoav Gilad and Doron Lancet
    Citation: BMC Genomics 2016 17:619
  25. B chromosomes are dispensable and variable karyotypic elements found in some species of animals, plants and fungi. They often originate from duplications and translocations of host genomic regions or result fr...

    Authors: Alexey I. Makunin, Ilya G. Kichigin, Denis M. Larkin, Patricia C. M. O’Brien, Malcolm A. Ferguson-Smith, Fengtang Yang, Anastasiya A. Proskuryakova, Nadezhda V. Vorobieva, Ekaterina N. Chernyaeva, Stephen J. O’Brien, Alexander S. Graphodatsky and Vladimir A. Trifonov
    Citation: BMC Genomics 2016 17:618
  26. Transfer RNAs (tRNAs) are ubiquitous in all living organism. They implement the genetic code so that most genomes contain distinct tRNAs for almost all 61 codons. They behave similar to mobile elements and pro...

    Authors: Cristian A. Velandia-Huerto, Sarah J. Berkemer, Anne Hoffmann, Nancy Retzlaff, Liliana C. Romero Marroquín, Maribel Hernández-Rosales, Peter F. Stadler and Clara I. Bermúdez-Santana
    Citation: BMC Genomics 2016 17:617
  27. The white-rot fungus Phlebia sp. MG-60 shows valuable properties such as high ethanol yield from several lignocellulosic materials, although white-rot fungi commonly degrade woody components to CO2 and H2O. In or...

    Authors: Jianqiao Wang, Tomohiro Suzuki, Hideo Dohra, Shoko Takigami, Hiroko Kako, Ayumi Soga, Ichiro Kamei, Toshio Mori, Hirokazu Kawagishi and Hirofumi Hirai
    Citation: BMC Genomics 2016 17:616
  28. Lasiodiplodia theobromae is a fungus of the Botryosphaeriaceae that causes grapevine vascular disease, especially in regions with hot climates. Fungi in this group often remain latent ...

    Authors: Marcos Paolinelli-Alfonso, José Manuel Villalobos-Escobedo, Philippe Rolshausen, Alfredo Herrera-Estrella, Clara Galindo-Sánchez, José Fabricio López-Hernández and Rufina Hernandez-Martinez
    Citation: BMC Genomics 2016 17:615
  29. Long noncoding RNAs (lncRNAs) represent a class of RNA molecules that are implicated in regulation of gene expression in both mammals and plants. While much progress has been made in determining the biological...

    Authors: Stanford Kwenda, Paul R. J. Birch and Lucy N. Moleleki
    Citation: BMC Genomics 2016 17:614
  30. Bean common mosaic virus (BCMV) is widespread, with Phaseolus species as the primary host plants. Numerous BCMV strains have been identified on the basis of a panel of bean varieties t...

    Authors: Kathleen Martin, Jugpreet Singh, John H. Hill, Steven A. Whitham and Steven B. Cannon
    Citation: BMC Genomics 2016 17:613
  31. Color patterns in angiosperm flowers are produced by spatially and temporally restricted deposition of pigments. Identifying the mechanisms responsible for restricted pigment deposition is a topic of broad int...

    Authors: Kazuma Suzuki, Tomohiro Suzuki, Takashi Nakatsuka, Hideo Dohra, Masumi Yamagishi, Kohei Matsuyama and Hideyuki Matsuura
    Citation: BMC Genomics 2016 17:611
  32. Populations of Atlantic salmon display highly significant genetic differences with unresolved molecular basis. These differences may result from separate postglacial colonization patterns, diversifying natural...

    Authors: Erik Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Vidar Wennevik, Geir Dahle, Eero Niemelä, Mikhail Ozerov, Juha-Pekka Vähä, Kevin A. Glover, Carl J. Rubin, Anna Wargelius and Rolf B. Edvardsen
    Citation: BMC Genomics 2016 17:610
  33. A large number of human inherited and acquired diseases and phenotypes are caused by mutations in G protein-coupled receptors (GPCR). Genome-wide association studies (GWAS) have shown that variations in the ADGRD...

    Authors: Liane Fischer, Caroline Wilde, Torsten Schöneberg and Ines Liebscher
    Citation: BMC Genomics 2016 17:609
  34. Fusarium fujikuroi is the causal agent of bakanae, the most significant seed-borne disease of rice. Molecular mechanisms regulating defence responses of rice towards this fungus are no...

    Authors: Slavica Matić, Paolo Bagnaresi, Chiara Biselli, Luigi Orru’, Greice Amaral Carneiro, Ilenia Siciliano, Giampiero Valé, Maria Lodovica Gullino and Davide Spadaro
    Citation: BMC Genomics 2016 17:608
  35. Phytophthora root and stem rot is one of the most yield-limiting diseases of soybean [Glycine max (L.) Merr], caused by the oomycete Phytophthora sojae. Partial resistance is controlled by several genes and, comp...

    Authors: Rhiannon Schneider, William Rolling, Qijian Song, Perry Cregan, Anne E. Dorrance and Leah K. McHale
    Citation: BMC Genomics 2016 17:607
  36. Peanut zygotes typically divide a few times to form a pre-embryo before further embryonic development halts under normal day/night photoperiods. Ovary elongation, however, continuesforming a downward growing p...

    Authors: Ye Zhang, Pengfei Wang, Han Xia, Chuanzhi Zhao, Lei Hou, Changsheng Li, Chao Gao, Shuzhen Zhao and Xingjun Wang
    Citation: BMC Genomics 2016 17:606

    The Erratum to this article has been published in BMC Genomics 2016 17:836

  37. Nuclear factor Y (NF-Y) transcription factor is composed of three distinct subunits: NF-YA, NF-YB and NF-YC. Many members of NF-Y family have been reported to be key regulators in plant development, phytohormo...

    Authors: Chong Ren, Zhan Zhang, Yi Wang, Shaohua Li and Zhenchang Liang
    Citation: BMC Genomics 2016 17:605
  38. Genomic selection (GS) is a promising approach for decreasing breeding cycle length in forest trees. Assessment of progeny performance and of the prediction accuracy of GS models over generations is therefore ...

    Authors: Jérôme Bartholomé, Joost Van Heerwaarden, Fikret Isik, Christophe Boury, Marjorie Vidal, Christophe Plomion and Laurent Bouffier
    Citation: BMC Genomics 2016 17:604
  39. The transition between pregnancy and lactation is a major physiological change for dairy cows. Complex systemic and local processes involving regulation of energy balance, galactopoiesis, utilisation of body r...

    Authors: Bruce Moran, Sean B. Cummins, Christopher J. Creevey and Stephen T. Butler
    Citation: BMC Genomics 2016 17:603
  40. Postnatal development of the mammalian mucosal immune system is crucial for responding to the rapid colonization by commensal bacteria and possible exposure to pathogens. This study analyzed expression pattern...

    Authors: Guanxiang Liang, Nilusha Malmuthuge, Hua Bao, Paul Stothard, Philip J. Griebel and Le Luo Guan
    Citation: BMC Genomics 2016 17:602
  41. High throughput protein expression studies can be performed using bead-based protein immunoassays, such as the Luminex® xMAP® technology. Technical variability is inherent to these experiments and may lead to ...

    Authors: Tanja K. Rausch, Arne Schillert, Andreas Ziegler, Angelika Lüking, Hans-Dieter Zucht and Peter Schulz-Knappe
    Citation: BMC Genomics 2016 17:601
  42. Green mold caused by Penicillium digitatum is the most damaging postharvest diseases of citrus fruit. Previously, we have observed that citral dose-dependently inhibited the mycelial growth of P. digitatum, with ...

    Authors: Qiuli OuYang, Nengguo Tao and Guoxing Jing
    Citation: BMC Genomics 2016 17:599
  43. High concentrations of atmospheric ammonia are one of the key environmental stressors affecting broiler production performance, which causes remarkable economic losses as well as potential welfare problems of ...

    Authors: Bao Yi, Liang Chen, Renna Sa, Ruqing Zhong, Huan Xing and Hongfu Zhang
    Citation: BMC Genomics 2016 17:598

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