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  1. Triatoma infestans is the main vector of Chagas disease in the Americas, currently transmitting it in Argentina, Paraguay, and Bolivia. Many T. infestans populations present insecticide resistance, reducing the e...

    Authors: Jose Manuel Latorre Estivalis, Lucila Traverso, Gina Pontes and Marcelo Gustavo Lorenzo
    Citation: BMC Genomics 2022 23:861
    Content type: Research Published on:

  2. Single cell mRNA sequencing technologies have transformed our understanding of cellular heterogeneity and identity. For sensitive discovery or clinical marker estimation where high transcript capture per cell ...

    Authors: Victoria Probst, Arman Simonyan, Felix Pacheco, Yuliu Guo, Finn Cilius Nielsen and Frederik Otzen Bagger
    Citation: BMC Genomics 2022 23:860
    Content type: Research article Published on:

  3. Publicly available RNA-seq datasets are often underused although being helpful to improve functional annotation of eukaryotic genomes. This is especially true for filamentous fungi genomes which structure diff...

    Authors: Gaëlle Lelandais, Damien Remy, Fabienne Malagnac and Pierre Grognet
    Citation: BMC Genomics 2022 23:859
    Content type: Research Published on:

  4. Sponges are interesting animal models for regeneration studies, since even from dissociated cells, they are able to regenerate completely. In particular, explants are model systems that can be applied to many ...

    Authors: Ana Riesgo, Nadia Santodomingo, Vasiliki Koutsouveli, Lars Kumala, Michelle M. Leger, Sally P. Leys and Peter Funch
    Citation: BMC Genomics 2022 23:858
    Content type: Research Published on:

  5. Bacterial genotyping is a crucial process in outbreak investigation and epidemiological studies. Several typing methods such as pulsed-field gel electrophoresis, multilocus sequence typing (MLST) and whole gen...

    Authors: Marketa Nykrynova, Vojtech Barton, Matej Bezdicek, Martina Lengerova and Helena Skutkova
    Citation: BMC Genomics 2022 23(Suppl 3):445
    Content type: Methodology Published on:

    This article is part of a Supplement: Volume 23 Supplement 3

  6. In the late phase of production, ducks untimely cease laying, leading to a lower feed conversion. Liver plays a vital role in the synthesis and transport of yolk materials during egg formation in birds. Howeve...

    Authors: Xue Du, Shujing Lai, Wanqiu Zhao, Xiaoqin Xu, Wenwu Xu, Tao Zeng, Yong Tian and Lizhi Lu
    Citation: BMC Genomics 2022 23:857
    Content type: Research Published on:

  7. The serum is rich in nutrients and plays an essential role in electrolyte and acid–base balance, maintaining cellular homeostasis. In addition, serum parameters have been commonly used as essential biomarkers ...

    Authors: Hehe Tang, He Zhang, Dapeng Liu, Zhen Wang, Daxin Yu, Wenlei Fan, Zhanbao Guo, Wei Huang, Shuisheng Hou and Zhengkui Zhou
    Citation: BMC Genomics 2022 23:856
    Content type: Research article Published on:

  8. As the amount of genomic data continues to grow, there is an increasing need for systematic ways to organize, explore, compare, analyze and share this data. Despite this, there is a lack of suitable platforms ...

    Authors: Thomas Roder, Simone Oberhänsli, Noam Shani and Rémy Bruggmann
    Citation: BMC Genomics 2022 23:855
    Content type: Software Published on:

  9. Phenotypic evolution is often caused by variation in gene expression resulting from altered gene regulatory mechanisms. Genetic variation affecting chromatin remodeling has been identified as a potential sourc...

    Authors: Henry A. Ertl, Mark S. Hill and Patricia J. Wittkopp
    Citation: BMC Genomics 2022 23:854
    Content type: Research Published on:

  10. Long non-coding RNAs (lncRNAs) are emerging as key modulators of inflammatory gene expression, but their roles in neuroinflammation are poorly understood. Here, we identified the inflammation-related lncRNAs a...

    Authors: Mina Baek, Jin Choul Chai, Hae In Choi, Eunyoung Yoo, Bert Binas, Young Seek Lee, Kyoung Hwa Jung and Young Gyu Chai
    Citation: BMC Genomics 2022 23:853
    Content type: Research Published on:

  12. In the analysis of single-cell RNA-sequencing (scRNA-seq) data, how to effectively and accurately identify cell clusters from a large number of cell mixtures is still a challenge. Low-rank representation (LRR)...

    Authors: Juan Wang, Nana Zhang, Shasha Yuan, Junliang Shang, Lingyun Dai, Feng Li and Jinxing Liu
    Citation: BMC Genomics 2022 23:851
    Content type: Research Published on:

  13. The gut microbiome has proven to be an important factor affecting obesity; however, it remains a challenge to identify consistent biomarkers across geographic locations and perform precisely targeted modulatio...

    Authors: Yaoliang Liu, Jinlin Zhu, Hongchao Wang, Wenwei Lu, Yuan Kun LEE, Jianxin Zhao and Hao Zhang
    Citation: BMC Genomics 2022 23:850
    Content type: Research Published on:

  14. Modern human brains and skull shapes differ from other hominids. Brain growth disorders as micro- (ASPM, MCPH1) and macrocephaly (NFIX, GLI3) have been highlighted as relevant for the evolution in humans due t...

    Authors: Vanessa I. Romero, Benjamin Arias-Almeida and Stefanie A. Aguiar
    Citation: BMC Genomics 2022 23:849
    Content type: Research Published on:

  15. The imbalance of intestinal flora may promote the occurrence and development of colorectal cancer, changes of the intestinal flora during the development of colorectal cancer and the mechanism that promotes th...

    Authors: Jingjing Liu, Wei Dong, Jian Zhao, Jing Wu, Jinqiang Xia, Shaofei Xie and Xiaofeng Song
    Citation: BMC Genomics 2022 23(Suppl 4):848
    Content type: Research Published on:

    This article is part of a Supplement: Volume 23 Supplement 4

  16. Toxocara canis is distributed worldwide, posing a serious threat to both human and dog health; however, the pathogenesis of T. canis infection in dogs remains unclear. In this study, the changes in microRNA (miRN...

    Authors: Jin Gao, Yang Zou, Xiao-Jing Wu, Yue Xu, Xing-Quan Zhu and Wen-Bin Zheng
    Citation: BMC Genomics 2022 23:847
    Content type: Research Published on:

  17. The ray and disc florets on the chrysanthemum capitulum are morphologically diverse and have remarkably abundant variant types, resulting in a rich variety of flower types. An anemone shape with pigmented and ...

    Authors: Jiawei Fan, Jialu Huang, Ya Pu, Yajing Niu, Mengmeng Zhang, Silan Dai and He Huang
    Citation: BMC Genomics 2022 23:846
    Content type: Research Published on:

  18. In insects, the chemosensory system is crucial in guiding their behaviors for survival. Plagiodera versicolora (Coleoptera: Chrysomelidae), is a worldwide leaf-eating forest pest in salicaceous trees. There is li...

    Authors: Zhe-Ran Wu, Jian-Ting Fan, Na Tong, Jin-Meng Guo, Yang Li, Min Lu and Xiao-Long Liu
    Citation: BMC Genomics 2022 23:845
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:242

  19. Tuberculosis is a serious infectious disease affecting millions of people. In spite of efforts to reduce the disease, increasing antibiotic resistance has contributed to persist in the top 10 causes of death w...

    Authors: Gabriel Morey-León, Derly Andrade-Molina, Juan Carlos Fernández-Cadena and Luisa Berná
    Citation: BMC Genomics 2022 23:844
    Content type: Research Published on:

  20. The cis-regulatory element became increasingly important for resistance breeding. There were many DNA variations identified by resequencing. To investigate the links between the DNA variations and cis-regulato...

    Authors: Qijun Xu, Shunmou Huang, Ganggang Guo, Chunbao Yang, Mu Wang, Xingquan Zeng and Yulin Wang
    Citation: BMC Genomics 2022 23:843
    Content type: Research Published on:

  21. Organisms in the wild can acquire disease- and stress-resistance traits that outstrip the programs endogenous to humans. Finding the molecular basis of such natural resistance characters is a key goal of evolu...

    Authors: Wenke Wang, Anna G. Flury, Andrew T. Rodriguez, Jennifer L. Garrison and Rachel B. Brem
    Citation: BMC Genomics 2022 23:842
    Content type: Research article Published on:

  22. RNA-sequencing has become a standard tool for analyzing gene activity in bulk samples and at the single-cell level. By increasing sample sizes and cell counts, this technique can uncover substantial informatio...

    Authors: Arif Harmanci, Akdes Serin Harmanci, Tiemo J. Klisch and Akash J. Patel
    Citation: BMC Genomics 2022 23:841
    Content type: Research article Published on:

  23. Skin autofluorescence (SAF) is a non-invasive measure reflecting accumulation of advanced glycation endproducts (AGEs) in the skin. Higher SAF levels are associated with an increased risk of developing type 2 ...

    Authors: Charlotte E. Vollenbrock, Delnaz Roshandel, Melanie M. van der Klauw, Bruce H. R. Wolffenbuttel and Andrew D. Paterson
    Citation: BMC Genomics 2022 23:840
    Content type: Research article Published on:

  24. Despite many improvements with in vitro culture systems, the quality and developmental ability of mammalian embryos produced in vitro are still lower than their in vivo counterparts. Though previous studies have ...

    Authors: Charles Banliat, Coline Mahé, Régis Lavigne, Emmanuelle Com, Charles Pineau, Valérie Labas, Benoit Guyonnet, Pascal Mermillod and Marie Saint-Dizier
    Citation: BMC Genomics 2022 23:839
    Content type: Research Published on:

  25. In our previous study, Citrobacter sp. XT1-2-2 was isolated from high cadmium-contaminated soils, and demonstrated an excellent ability to decrease the bioavailability of cadmium in the soil and inhibit cadmium u...

    Authors: Shiping Shan, Wei Cheng, Yilu Li, Min Zhang, Zhudong Liu, Yushuang Wang, Xiaowu Wei, Zujiao Fu, Shandong Wu, Dongxia Du and Zhaohui Guo
    Citation: BMC Genomics 2022 23:838
    Content type: Research Published on:

  26. European foulbrood is a significant bacterial brood disease of Apis sp. and can cause severe and devastating damages in beekeeping operations. Nevertheless, the epidemiology of its causative agent Melissococcus p...

    Authors: Oleg Lewkowski, Anja Poehlein, Rolf Daniel and Silvio Erler
    Citation: BMC Genomics 2022 23:837
    Content type: Research Published on:

  27. Sympathetic nerves play essential roles in the regulation of lung inflammation, and we investigated the effect of sympathetic denervation (SD) on sepsis-induced acute lung injury (ALI) in mice. Mice were rando...

    Authors: Jia Zhang, Zhao Zhang, Xinran Nie, Yingli Liu, Yong Qi and Jing Wang
    Citation: BMC Genomics 2022 23:836
    Content type: Research Published on:

  28. Despite the applications of Bacillus subtilis group species in various sectors, limited information is available regarding their phages. Here, 61 B. subtilis group species-infecting phages (BSPs) were studied for...

    Authors: Haftom Baraki Abraha, Jae-Won Lee, Gayeong Kim, Mokhammad Khoiron Ferdiansyah, Rathnayaka Mudiyanselage Ramesha and Kwang-Pyo Kim
    Citation: BMC Genomics 2022 23:835
    Content type: Research Published on:

  29. Bis-(3′-5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) is a bacterial second messenger that affects diverse processes in different bacteria, including the cell cycle, motility, and biofilm formation. It...

    Authors: Sonja Koppenhöfer and Andrew S. Lang
    Citation: BMC Genomics 2022 23:834
    Content type: Research Published on:

  30. The yak is the most important livestock in the Qinghai-Tibet Plateau, and body weight directly affects the economic values of yak. Up to date, the genome-wide profiling of single-nucleotide polymorphisms (SNPs...

    Authors: Hui Jiang, Zhi-Xin Chai, Han-Wen Cao, Cheng-Fu Zhang, Yong Zhu, Qiang Zhang and Jin-Wei Xin
    Citation: BMC Genomics 2022 23:833
    Content type: Research Published on:

  31. The Nile tilapia (Oreochromis niloticus) is the third most important freshwater fish for aquaculture. Its success is directly linked to continuous breeding efforts focusing on production traits such as growth rat...

    Authors: G. J. Etherington, W. Nash, A. Ciezarek, T. K. Mehta, A. Barria, C. Peñaloza, M. G. Q. Khan, A. Durrant, N. Forrester, F. Fraser, N. Irish, G. G. Kaithakottil, J. Lipscombe, T. Trong, C. Watkins, D. Swarbreck…
    Citation: BMC Genomics 2022 23:832
    Content type: Research Published on:

  32. The markers detected by genome-wide association study (GWAS) make it possible to dissect genetic structure and diversity at many loci. This can enable a wheat breeder to reveal and used genomic loci controllin...

    Authors: Ehsan Rabieyan, Mohammad Reza Bihamta, Mohsen Esmaeilzadeh Moghaddam, Valiollah Mohammadi and Hadi Alipour
    Citation: BMC Genomics 2022 23:831
    Content type: Research Published on:

  33. Structural variations (SVs) have recently become a topic of great interest in the area of genetic diversity and trait regulation. As genomic sequencing technologies have rapidly advanced, longer reads have bee...

    Authors: Yueyuan Liu, Mingyue Zhang, Runze Wang, Benping Li, Yafei Jiang, Manyi Sun, Yaojun Chang and Jun Wu
    Citation: BMC Genomics 2022 23:830
    Content type: Research Published on:

  34. Heat stress has a substantial negative economic impact on the dairy industry. N6-methyladenosine (m6A) is the most common internal RNA modification in eukaryotes and plays a key role in regulating heat stress ...

    Authors: Ying Qi, Yiming Zhang, Jing Zhang, Jing Wang and Qiuling Li
    Citation: BMC Genomics 2022 23:829
    Content type: Research Published on:

  35. The deep-sea mussel Gigantidas haimaensis is a representative species from the Haima cold seep ecosystem in the South China Sea that establishes endosymbiosis with chemotrophic bacteria. During long-term evolutio...

    Authors: Hua Zhang, Gaoyou Yao and Maoxian He
    Citation: BMC Genomics 2022 23:828
    Content type: Research Published on:

  36. Inferring historical population admixture events yield essential insights in understanding a species demographic history. Methods are available to infer admixture events in demographic history with extant gene...

    Authors: Yonghui Wang, Zicheng Zhao, Xinyao Miao, Yinan Wang, Xiaobo Qian, Lingxi Chen, Changfa Wang and Shuaicheng Li
    Citation: BMC Genomics 2022 23(Suppl 4):827
    Content type: Software Published on:

    This article is part of a Supplement: Volume 23 Supplement 4

  37. F. nucleatum, as an important periodontal pathogen, is not only closely associated with the development of periodontitis, but also implicated in systemic diseases. Macrophages may act as an important mediator in...

    Authors: Jieyu Zhou, Lin Liu, Peiyao Wu, Lei Zhao and Yafei Wu
    Citation: BMC Genomics 2022 23:826
    Content type: Research Published on:

  38. The transition from fertilized egg to embryo in chicken requires activation of hundreds of genes that were mostly inactivated before fertilization, which is accompanied with various biological processes. Undou...

    Authors: Liqin Liao, Ziqi Yao, Jie Kong, Xinheng Zhang, Hongxin Li, Weiguo Chen and Qingmei Xie
    Citation: BMC Genomics 2022 23:825
    Content type: Research Published on:

  39. The solute carrier 4 (SLC4) gene family is involved in a variety of physiological processes in organisms and is essential for maintaining acid-base balance in the body. The slc4 genes have been extensively studie...

    Authors: Chuanjiang Zhou, Bo Hu, Yongtao Tang, Xin Chen, Zhigang Ma, Qiqi Ding and Guoxing Nie
    Citation: BMC Genomics 2022 23:824
    Content type: Research Published on:

  40. Embryonic and fetal development is very susceptible to the availability of nutrients that can interfere with the setting of epigenomes, thus modifying the main metabolic pathways and impacting the health and p...

    Authors: Aurélie Sécula, Lisa E. Bluy, Hervé Chapuis, Agnès Bonnet, Anne Collin, Laure Gress, Alexis Cornuez, Xavier Martin, Loys Bodin, Cécile M. D. Bonnefont and Mireille Morisson
    Citation: BMC Genomics 2022 23:823
    Content type: Research Published on:

  41. A loss-of-function mutation in ATPase phospholipid transporting 11-B (putative) (ATP11B) gene causing cerebral small vessel disease (SVD) in vivo, and a single intronic nucleotide polymorphism in ATP11B: rs148771...

    Authors: Wen-Kai Yu, Yun-Chao Wang, Yuan Gao, Chang-He Shi, Yu Fan, Lu-Lu Yu, Zi-Chen Zhao, Shan-Shan Li, Yu-Ming Xu and Yu-Sheng Li
    Citation: BMC Genomics 2022 23:822
    Content type: Research article Published on:

  42. Hungarian white goose has excellent down production performance and was introduced to China in 2010. The growth and development of feather follicles has an important impact on down production. Goose feather fo...

    Authors: Yupu Song, Chang Liu, Yuxuan Zhou, Guangyu Lin, Chenguang Xu, Petunia Msuthwana, Sihui Wang, Jingyun Ma, Fangming Zhuang, Xianou Fu, Yudong Wang, Tuoya Liu, Qianyan Liu, Jingbo Wang, Yujian Sui and Yongfeng Sun
    Citation: BMC Genomics 2022 23:821
    Content type: Research Published on:

  43. BBX genes are key players in the regulation of various developmental processes and stress responses, which have been identified and functionally characterized in many plant species. However, our understanding of...

    Authors: Binghui Shan, Guohua Bao, Tianran Shi, Lulu Zhai, Shaomin Bian and Xuyan Li
    Citation: BMC Genomics 2022 23:820
    Content type: Research Published on:

  44. As omics measurements profiled on different molecular layers are interconnected, integrative approaches that incorporate the regulatory effect from multi-level omics data are needed. When the multi-level omics...

    Authors: Wenqing Jiang, Roby Joehanes, Daniel Levy, George T O’Connor and Josée Dupuis
    Citation: BMC Genomics 2022 23:819
    Content type: Research Published on:

  45. Leuconostoc gelidum and Leuconostoc gasicomitatum have dual roles in foods. They may spoil cold-stored packaged foods but can also be beneficial in kimchi fermentation. The impact in food science as well as the l...

    Authors: Per Johansson, Elina Säde, Jenni Hultman, Petri Auvinen and Johanna Björkroth
    Citation: BMC Genomics 2022 23:818
    Content type: Research Published on:

  47. Freshwaters are exposed to multiple anthropogenic stressors, leading to habitat degradation and biodiversity decline. In particular, agricultural stressors are known to result in decreased abundances and commu...

    Authors: Marie V. Brasseur, Arne J. Beermann, Vasco Elbrecht, Daniel Grabner, Bianca Peinert-Voss, Romana Salis, Martina Weiss, Christoph Mayer and Florian Leese
    Citation: BMC Genomics 2022 23:816
    Content type: Research Published on:

  48. Causal variants for complex traits, such as eQTL are often found in non-coding regions of the genome, where they are hypothesised to influence phenotypes by regulating gene expression. Many regulatory regions ...

    Authors: Claire P. Prowse-Wilkins, Thomas J. Lopdell, Ruidong Xiang, Christy J. Vander Jagt, Mathew D. Littlejohn, Amanda J. Chamberlain and Michael E. Goddard
    Citation: BMC Genomics 2022 23:815
    Content type: Research Published on:

  49. As the direct organ of villus, hair follicles have obvious seasonal cycles. The hair follicle cycle is orchestrated by multiple cell types that together direct cell renewal and differentiation. But the regulat...

    Authors: Qingbo Zheng, Na Ye, Pengjia Bao, Xiaolan Zhang, Fubin Wang, Lanhua Ma, Min Chu, Xian Guo, Chunnian Liang, Heping Pan and Ping Yan
    Citation: BMC Genomics 2022 23:813
    Content type: Research Published on:

    The Correction to this article has been published in BMC Genomics 2023 24:60

  50. Dof transcription factors (TFs) containing C2-C2 zinc finger domains are plant-specific regulatory proteins, playing crucial roles in a variety of biological processes. However, little is known about Dof in Camel...

    Authors: Tao Luo, Yanan Song, Huiling Gao, Meng Wang, Hongli Cui, Chunli Ji, Jiping Wang, Lixia Yuan and Runzhi Li
    Citation: BMC Genomics 2022 23:812
    Content type: Research Published on:

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BMC Genomics

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