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6358 result(s) for 'general transcription factors vs specific' within BMC Genomics

Page 38 of 128

  1. Phosphorus (P) plays important roles in plant growth and development. MicroRNAs involved in P signaling have been identified in Arabidopsis and rice, but P-responsive microRNAs and their targets in soybean lea...

    Authors: Feng Xu, Qian Liu, Luying Chen, Jiebin Kuang, Thomas Walk, Jinxiang Wang and Hong Liao
    Citation: BMC Genomics 2013 14:66
    Content type: Research article Published on:

  2. Micro-RNAs (miRNA) are attributed to the systems biological role of a regulatory mechanism of the expression of protein coding genes. Research has identified miRNAs dysregulations in several but distinct patho...

    Authors: Alfred Ultsch and Jörn Lötsch
    Citation: BMC Genomics 2014 15:976
    Content type: Research article Published on:

  3. “Stoichioproteomics” relates the elemental composition of proteins and proteomes to variation in the physiological and ecological environment. To help harness and explore the wealth of hypotheses made possible...

    Authors: James D J Gilbert, Claudia Acquisti, Holly M Martinson, James J Elser, Sudhir Kumar and William F Fagan
    Citation: BMC Genomics 2013 14:599
    Content type: Research article Published on:

  4. Splicing is a genetic process that has important implications in several diseases including cancer. Deciphering the complex rules of splicing regulation is crucial to understand and treat splicing-related dise...

    Authors: Fernando Carazo, Marian Gimeno, Juan A. Ferrer-Bonsoms and Angel Rubio
    Citation: BMC Genomics 2019 20:521
    Content type: Research article Published on:

  5. CpG dinucleotide-rich genomic DNA regions, known as CpG islands (CGIs), can be methylated at their cytosine residues as an epigenetic mark that is stably inherited during cell mitosis. Differentially methylate...

    Authors: Sergio Cocozza, Giovanni Scala, Gennaro Miele, Imma Castaldo and Antonella Monticelli
    Citation: BMC Genomics 2013 14:692
    Content type: Research article Published on:

  6. Significant gaps remain regarding the pathomechanisms underlying the autoimmune response in vitiligo (VL), where the loss of self-tolerance leads to the targeted killing of melanocytes. Specifically, there is ...

    Authors: Rama Dey-Rao and Animesh A. Sinha
    Citation: BMC Genomics 2017 18:109
    Content type: Research article Published on:

  8. Resident macrophages in the CNS microglia become activated and produce proinflammatory molecules upon encountering bacteria or viruses. TLRs are a phylogenetically conserved diverse family of sensors that driv...

    Authors: Amitabh Das, Jin Choul Chai, Sun Hwa Kim, Young Seek Lee, Kyoung Sun Park, Kyoung Hwa Jung and Young Gyu Chai
    Citation: BMC Genomics 2015 16:517
    Content type: Research article Published on:

  9. Parkinson’s disease (PD) is a degenerative disease with early-stage pathology hypothesized to manifest in brainstem regions. Vocal deficits, including soft, monotone speech, result in significant clinical and ...

    Authors: Cynthia A. Kelm-Nelson and Stephen Gammie
    Citation: BMC Genomics 2020 21:625
    Content type: Research article Published on:

  10. Visceral white adipose tissue (WAT) hypertrophy, adipokine production, inflammation and fibrosis are strongly associated with obesity, but the time-course of these changes in-vivo are not fully understood. Theref...

    Authors: Eun-Young Kwon, Su-Kyung Shin, Yun-Young Cho, Un Ju Jung, Eunjung Kim, Taesun Park, Jung Han Yoon Park, Jong Won Yun, Robin A McGregor, Yong Bok Park and Myung-Sook Choi
    Citation: BMC Genomics 2012 13:450
    Content type: Research article Published on:

  11. To identify the key elements controlling grain production in maize, it is essential to have an integrated view of the responses to alterations in the main steps of nitrogen assimilation by modification of gene...

    Authors: Nardjis Amiour, Sandrine Imbaud, Gilles Clément, Nicolas Agier, Michel Zivy, Benoît Valot, Thierry Balliau, Isabelle Quilleré, Thérèse Tercé-Laforgue, Céline Dargel-Graffin and Bertrand Hirel
    Citation: BMC Genomics 2014 15:1005
    Content type: Research article Published on:

  12. CCN2/CTGF is an established effector of TGFβ driven responses in diabetic nephropathy. We have identified an interaction between CCN2 and TGFβ leading to altered phenotypic differentiation and inhibited cellul...

    Authors: Noel Faherty, Helen O’Donovan, David Kavanagh, Stephen Madden, Gareth J McKay, Alexander P Maxwell, Finian Martin, Catherine Godson and John Crean
    Citation: BMC Genomics 2013 14:525
    Content type: Research article Published on:

  13. Tissue-specific fat deposition is regulated by a series of complex regulatory mechanisms. Reports indicate that epigenetic regulators, such as circular RNAs (circRNAs), are crucial in diseases progression, ani...

    Authors: Meng Zhang, Yu Han, Yanhui Zhai, Xiangfei Ma, Xinglan An, Sheng Zhang and Ziyi Li
    Citation: BMC Genomics 2020 21:594
    Content type: Research article Published on:

  14. The differentiation of bone marrow mesenchymal stem cells is a complex and dynamic process. The gene expression pattern and mechanism of different periods of adipogenic and osteogenic differentiation remain un...

    Authors: Yu Liu, Markus Tingart, Sophie Lecouturier, Jianzhang Li and Jörg Eschweiler
    Citation: BMC Genomics 2021 22:254
    Content type: Research article Published on:

  15. Periparturient cows release fatty acid reserves from adipose tissue (AT) through lipolysis in response to the negative energy balance induced by physiological changes related to parturition and the onset of la...

    Authors: David Salcedo-Tacuma, Jair Parales-Giron, Crystal Prom, Miguel Chirivi, Juliana Laguna, Adam L. Lock and G. Andres Contreras
    Citation: BMC Genomics 2020 21:824
    Content type: Research article Published on:

  16. Noncoding RNA (ncRNA) has been recognized as an important regulator of gene expression networks in Bacteria and Eucaryota. Little is known about ncRNA in thermococcal archaea except for the eukaryotic-like C/D...

    Authors: Kounthéa Phok, Annick Moisan, Dana Rinaldi, Nicolas Brucato, Agamemnon J Carpousis, Christine Gaspin and Béatrice Clouet-d'Orval
    Citation: BMC Genomics 2011 12:312
    Content type: Research article Published on:

  18. Recently, a number of high-resolution genome-wide maps of nucleosome locations in S. cerevisiae have been derived experimentally. However, nucleosome positions are determined in vivo by the combined effects of...

    Authors: Jihua Feng, Xianhua Dai, Qian Xiang, Zhiming Dai, Jiang Wang, Yangyang Deng and Caisheng He
    Citation: BMC Genomics 2010 11:33
    Content type: Research article Published on:

  19. Non-coding RNAs (ncRNAs), which perform diverse regulatory roles, have been found in organisms from all superkingdoms of life. However, there have been limited numbers of studies on the functions of ncRNAs, es...

    Authors: Yoo-Bok Cho, Eun Ju Lee, Suhyung Cho, Tae Yong Kim, Jin Hwan Park and Byung-Kwan Cho
    Citation: BMC Genomics 2016 17:154
    Content type: Research article Published on:

  20. Sugarcane smut caused by Sporisorium scitamineum leads to a significant reduction in cane yield and sucrose content. MicroRNAs (miRNAs) play an important role in regulating plant responses to biotic stress. The p...

    Authors: Yachun Su, Yuye Zhang, Ning Huang, Feng Liu, Weihua Su, Liping Xu, Waqar Ahmad, Qibin Wu, Jinlong Guo and Youxiong Que
    Citation: BMC Genomics 2017 18:325
    Content type: Research article Published on:

  21. In a recent study it was demonstrated that a largely increased ovulation number is responsible for high prolificacy in two mouse lines selected for fertility performance. The objective of the present study was...

    Authors: Jens Vanselow, Gerd Nürnberg, Dirk Koczan, Martina Langhammer, Hans-Jürgen Thiesen and Norbert Reinsch
    Citation: BMC Genomics 2008 9:307
    Content type: Research article Published on:

  22. The Saccharomyces cerevisiae MYO1 gene encodes the myosin II heavy chain (Myo1p), a protein required for normal cytokinesis in budding yeast. Myo1p deficiency in yeast (myo1Δ) causes a cell separation defect char...

    Authors: José F Rodríguez-Quiñones, Rafael A Irizarry, Nitza L Díaz-Blanco, Félix E Rivera-Molina, Diana Gómez-Garzón and José R Rodríguez-Medina
    Citation: BMC Genomics 2008 9:34
    Content type: Research article Published on:

  23. In the domestic dog, corpora lutea (CL) are the only source of progesterone (P4), both in pregnant and non-pregnant cycles because there is no placental steroidogenesis. The absence of an endogenous luteolysin...

    Authors: Sophie Zatta, Hubert Rehrauer, Aykut Gram, Alois Boos and Mariusz Pawel Kowalewski
    Citation: BMC Genomics 2017 18:757
    Content type: Research article Published on:

  24. MicroRNAs (miRNAs), a group of short non-coding RNAs that negatively regulate gene expression, have recently emerged as potential modulators of cellular response to ionizing radiations both in vitro and in vivo i...

    Authors: Nicolas Joly-Tonetti, José Viñuelas, Olivier Gandrillon and Jérôme Lamartine
    Citation: BMC Genomics 2013 14:184
    Content type: Research article Published on:

  25. Lake Baikal is one of the oldest freshwater lakes and has constituted a stable environment for millions of years, in stark contrast to small, transient bodies of water in its immediate vicinity. A highly diver...

    Authors: Polina Drozdova, Lorena Rivarola-Duarte, Daria Bedulina, Denis Axenov-Gribanov, Stephan Schreiber, Anton Gurkov, Zhanna Shatilina, Kseniya Vereshchagina, Yulia Lubyaga, Ekaterina Madyarova, Christian Otto, Frank Jühling, Wibke Busch, Lena Jakob, Magnus Lucassen, Franz Josef Sartoris…
    Citation: BMC Genomics 2019 20:712
    Content type: Research Article Published on:

  26. ST08 and ST09 are potent curcumin derivatives with antiproliferative, apoptotic, and migrastatic properties. Both ST08 and ST09 exhibit in vitro and in vivo anticancer properties. As reported earlier, these de...

    Authors: Snehal Nirgude, Sagar Desai and Bibha Choudhary
    Citation: BMC Genomics 2022 23:807
    Content type: Research Published on:

  27. The weight that gene copy number plays in transcription remains controversial; although in specific cases gene expression correlates with copy number, the relationship cannot be inferred at the global level. W...

    Authors: Tara L Spivey, Valeria De Giorgi, Yingdong Zhao, Davide Bedognetti, Zoltan Pos, Qiuzhen Liu, Sara Tomei, Maria Libera Ascierto, Lorenzo Uccellini, Jennifer Reinboth, Lotfi Chouchane, David F Stroncek, Ena Wang and Francesco M Marincola
    Citation: BMC Genomics 2012 13:156
    Content type: Research article Published on:

  28. Orb-web and cob-web weaving spiders spin dragline silk fibers that are among the strongest materials known. Draglines are primarily composed of MaSp1 and MaSp2, two spidroins (spider fibrous proteins) expresse...

    Authors: Amanda Kelly Lane, Cheryl Y Hayashi, Gregg B Whitworth and Nadia A Ayoub
    Citation: BMC Genomics 2013 14:846
    Content type: Research article Published on:

  29. Recovery growth is a phase of rapid growth that is triggered by adequate refeeding of animals following a period of weight loss caused by starvation. In this study, to obtain more information on the system-wid...

    Authors: Pierre-Yves Rescan, Jerome Montfort, Cécile Rallière, Aurélie Le Cam, Diane Esquerré and Karine Hugot
    Citation: BMC Genomics 2007 8:438
    Content type: Research article Published on:

  30. A fundamental question in neuroscience is how memories are stored and retrieved in the brain. Long-term memory formation requires transcription, translation and epigenetic processes that control gene expressio...

    Authors: Lucia L Peixoto, Mathieu E Wimmer, Shane G Poplawski, Jennifer C Tudor, Charles A Kenworthy, Shichong Liu, Keiko Mizuno, Benjamin A Garcia, Nancy R Zhang, K Peter Giese and Ted Abel
    Citation: BMC Genomics 2015 16(Suppl 5):S5
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 5

  31. Infectious Salmon Anaemia Virus (ISAV) is an Orthomixovirus that represents a large problem for salmonid aquaculture worldwide. Current prevention and treatment methods are only partially effective. Genetic se...

    Authors: Ophélie Gervais, Carolina Peñaloza, Remi Gratacap, Athina Papadopoulou, Mariana Beltrán, Neil C. Henderson, Ross D. Houston, Musa A. Hassan and Diego Robledo
    Citation: BMC Genomics 2023 24:161
    Content type: Research Published on:

  32. Pituitary tumor transforming gene (PTTG), also known as securin, is highly expressed in various tumors including pituitary, thyroid, colon, ovary, testis, lung, and breast. An overexpression of PTTG enhances c...

    Authors: Siva K Panguluri and Sham S Kakar
    Citation: BMC Genomics 2009 10:577
    Content type: Research article Published on:

  33. Transcription factor binding is regulated by several interactions, primarily involving cis-element binding. These binding sites maintain specificity by means of their sequence, and other additional factors such a...

    Authors: Rajesh Mehrotra, Sachin Sethi, Ipshita Zutshi, Purva Bhalothia and Sandhya Mehrotra
    Citation: BMC Genomics 2013 14:203
    Content type: Research article Published on:

  34. Leishmania infantum is the etiological agent of zoonotical visceral leishmaniasis in the Mediterranean basin. A recent outbreak in humans has been recently reported in central Spain. Leishmania spp. parasites are...

    Authors: Pedro J Alcolea, Ana Alonso, Manuel J Gómez, Marina Postigo, Ricardo Molina, Maribel Jiménez and Vicente Larraga
    Citation: BMC Genomics 2014 15:849
    Content type: Research article Published on:

  35. Elucidating the effects of geography and selection on genetic variation is critical for understanding the relative importance of adaptation in driving differentiation and identifying the environmental factors ...

    Authors: Li Liu, Zhen Wang, Yingjuan Su and Ting Wang
    Citation: BMC Genomics 2021 22:388
    Content type: Research article Published on:

  36. Selection programs for growth and stress traits in cultured fish are fundamental to the improvement of aquaculture production. The gilthead sea bream (Sparus aurata) is the main aquacultured species in the Medite...

    Authors: Josep A Calduch-Giner, Grace Davey, Alfonso Saera-Vila, Benoit Houeix, Anita Talbot, Patrick Prunet, Michael T Cairns and Jaume Pérez-Sánchez
    Citation: BMC Genomics 2010 11:193
    Content type: Research article Published on:

  38. Malignant cells in tumours of B-cell origin account for 0.1% to 98% of the total cell content, depending on disease entity. Recently, gene expression profiles (GEPs) of B-cell lymphomas based on microarray tec...

    Authors: Maria Bro Kloster, Anders Ellern Bilgrau, Maria Rodrigo-Domingo, Kim Steve Bergkvist, Alexander Schmitz, Mads Sønderkær, Julie Støve Bødker, Steffen Falgreen, Mette Nyegaard, Hans Erik Johnsen, Kåre Lehmann Nielsen, Karen Dybkaer and Martin Bøgsted
    Citation: BMC Genomics 2012 13:596
    Content type: Methodology article Published on:

  39. Fatty acids (FA) play a critical role in energy homeostasis and metabolic diseases; in the context of livestock species, their profile also impacts on meat quality for healthy human consumption. Molecular path...

    Authors: Yuliaxis Ramayo-Caldas, Maria Ballester, Marina RS Fortes, Anna Esteve-Codina, Anna Castelló, Jose L Noguera, Ana I Fernández, Miguel Pérez-Enciso, Antonio Reverter and Josep M Folch
    Citation: BMC Genomics 2014 15:232
    Content type: Research article Published on:

  40. MeFtsZ2-1 is a key gene for plant plastid division, but the mechanism by which MeFtsZ2-1 affects pigment accumulation in cassava (Manihot esculenta Crantz) through plastids remains unclear. We found that MeFtsZ2-...

    Authors: Yuwei Zang, Kunlin Wu, Liangwang Liu, Fangfang Ran, Changyi Wang, Shuwen Wu, Dayong Wang, Jianchun Guo and Yi Min
    Citation: BMC Genomics 2024 25:448
    Content type: Research Published on:

  42. The Mediterranean mussel (Mytilus galloprovincialis) is a cosmopolitan, cultured bivalve with worldwide commercial and ecological importance. However, there is a qualitative and quantitative lack of knowledge of ...

    Authors: Rebeca Moreira, Patricia Pereiro, Carlos Canchaya, David Posada, Antonio Figueras and Beatriz Novoa
    Citation: BMC Genomics 2015 16:728
    Content type: Research article Published on:

  43. Due to its strong abiotic stress tolerance, common vetch is widely cultivated as a green manure and forage crop in grass and crop rotation systems. The comprehensive molecular mechanisms activated in common ve...

    Authors: Rui Dong, Ben Luo, Li Tang, Qiu-xia Wang, Zhong-Jie Lu, Chao Chen, Feng Yang, Song Wang and Jin He
    Citation: BMC Genomics 2022 23:814
    Content type: Research Published on:

  44. Hollow heart is a kind of physiological defect that seriously affects the yield, quality, and economic value of cucumber. However, the formation of hollow hearts may relate to multiple factors in cucumber, and...

    Authors: Jiaxi Li, Chenran Gu, Yanwen Yuan, Zeyuan Gao, Zhiwei Qin and Ming Xin
    Citation: BMC Genomics 2024 25:36
    Content type: Research Published on:

  45. A transcriptomic approach was used to evaluate potential interactions between prepartum body condition score (BCS) and feeding management in the weeks before calving on hepatic metabolism during the peripartur...

    Authors: M. Vailati-Riboni, S. Meier, C. R. Burke, J. K. Kay, M. D. Mitchell, C. G. Walker, M. A. Crookenden, A. Heiser, S. L. Rodriguez-Zas, J. R. Roche and J. J. Loor
    Citation: BMC Genomics 2016 17:854
    Content type: Research article Published on:

  46. Physiological processes occur in many species for which there is yet no sequenced genome and for which we would like to identify the genetic basis. For example, some species increase their vascular network to ...

    Authors: John MJ Herbert, Francesca M Buffa, Henrik Vorschmitt, Stuart Egginton and Roy Bicknell
    Citation: BMC Genomics 2009 10:490
    Content type: Methodology article Published on:

  48. Maternal mRNA provisioning of oocytes regulates early embryogenesis. Maternal transcripts are degraded as zygotic genome activation (ZGA) intensifies, a phenomenon known as the maternal-to-zygotic transition (...

    Authors: Erin Chille, Emma Strand, Mayaan Neder, Valeria Schmidt, Madeleine Sherman, Tali Mass and Hollie Putnam
    Citation: BMC Genomics 2021 22:815
    Content type: Research Published on:

  49. Several studies have mined short-read RNA sequencing datasets to identify long non-coding RNAs (lncRNAs), and others have focused on the function of individual lncRNAs in abiotic stress response. However, our ...

    Authors: Yuanda Lv, Fengqin Hu, Yongfeng Zhou, Feilong Wu and Brandon S. Gaut
    Citation: BMC Genomics 2019 20:864
    Content type: Research article Published on:

  50. Individuals with schizophrenia (SCZ) have, on average, a 10- to 20-year shorter expected life span than the rest of the population, primarily due to cardiovascular disease comorbidity. Genome-wide association ...

    Authors: Qian He, Adam N. Bennett, Jundong Liu, Beifang Fan, Xue Han, Lu Cheng, Yan Chen, Xia Yang and Kei Hang Katie Chan
    Citation: BMC Genomics 2022 23:617
    Content type: Research Published on:

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