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6358 result(s) for 'general transcription factors vs specific' within BMC Genomics

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  1. Paris polyphylla is a herb widely used in traditional Chinese medicine to treat various diseases. Stem rot diseases seriously affected the yield of P. polyphylla in subtropical areas of China. Therefore, cost-eff...

    Authors: Aiming Jiang, Chengwu Zou, Xiang Xu, Zunwei Ke, Jiangan Hou, Guihe Jiang, Chunli Fan, Jianhua Gong and Jiguang Wei
    Citation: BMC Genomics 2022 23:161
    Content type: Research Published on:

  2. Selenium (Se) is required for the synthesis of proteins (selenoproteins) with essential biological functions. Selenoproteins have a crucial role in the maintenance of cellular redox homeostasis in nearly all t...

    Authors: D. Pacitti, M. M. Lawan, J. Feldmann, J. Sweetman, T. Wang, S. A. M. Martin and C. J. Secombes
    Citation: BMC Genomics 2016 17:116
    Content type: Research article Published on:

  3. Chromatin in the nucleus of all eukaryotes is organized into a system of loops and domains. These loops remain fastened at their bases to the fundamental framework of the nucleus, the matrix or the scaffold. T...

    Authors: Sushma S Padmaja, Jagannathan Lakshmanan, Ravi Gupta, Santanu Banerjee, Pennathur Gautam and Sulagna Banerjee
    Citation: BMC Genomics 2010 11:386
    Content type: Research article Published on:

  5. In Bacillus subtilis and its relatives carbon catabolite control, a mechanism enabling to reach maximal efficiency of carbon and energy sources metabolism, is achieved by the global regulator CcpA (carbon catabol...

    Authors: Bogumiła C Marciniak, Monika Pabijaniak, Anne de Jong, Robert Dűhring, Gerald Seidel, Wolfgang Hillen and Oscar P Kuipers
    Citation: BMC Genomics 2012 13:401
    Content type: Research article Published on:

  6. Cynanchum komarovii Al Iljinski is a xerophytic plant species widely distributing in the severely adverse environment of the deserts in northwest China. At present, the detailed transc...

    Authors: Xiaowen Ma, Ping Wang, Sihong Zhou, Yun Sun, Nana Liu, Xiaoning Li and Yuxia Hou
    Citation: BMC Genomics 2015 16:753
    Content type: Research article Published on:

  7. Metamorphosis is an important process in the life cycle of holometabolous insects and is regulated by insect hormones. During metamorphosis, the epidermis goes through a significant transformation at the bioch...

    Authors: Qiang Fu, Peng-Cheng Liu, Jin-Xing Wang, Qi-Sheng Song and Xiao-Fan Zhao
    Citation: BMC Genomics 2009 10:600
    Content type: Research article Published on:

  8. Gene expression regulators identified in transcriptome profiling experiments may serve as ideal targets for genetic manipulations in farm animals.

    Authors: Tinghua Huang, Min Yang, Kaihui Dong, Mingjiang Xu, Jinhui Liu, Zhi Chen, Shijia Zhu, Wang Chen, Jun Yin, Kai Jin, Yu Deng, Zhou Guan, Xiali Huang, Jun Yang, Rongxun Han and Min Yao
    Citation: BMC Genomics 2020 21:229
    Content type: Research article Published on:

  9. Microproteins, prevalent across all kingdoms of life, play a crucial role in cell physiology and human health. Although global gene transcription is widely explored and abundantly available, our understanding ...

    Authors: Bowen Zhao, Jing Zhao, Muyao Wang, Yangfan Guo, Aamir Mehmood, Weibin Wang, Yi Xiong, Shenggan Luo, Dong-Qing Wei, Xin-Qing Zhao and Yanjing Wang
    Citation: BMC Genomics 2023 24:661
    Content type: Database Published on:

  10. The development of abdominal fat and meat quality are closely related and can impact economic efficiency. In this study, we conducted transcriptome sequencing of the abdominal fat tissue of Gushi chickens at 6...

    Authors: Bin Zhai, Hongtai Li, Shuaihao Li, Jinxing Gu, Hongyuan Zhang, Yanhua Zhang, Hong Li, Yadong Tian, Guoxi Li and Yongcai Wang
    Citation: BMC Genomics 2023 24:386
    Content type: Research Published on:

  11. Nuclear receptors (NRs) are transcription factors which bind small hormones, whose evolutionary history and the presence of different functional surfaces makes them an interesting target for a correlation base...

    Authors: Marcelo Querino Lima Afonso, Leonardo Henrique França de Lima and Lucas Bleicher
    Citation: BMC Genomics 2013 14(Suppl 6):S1
    Content type: Research Published on:

    This article is part of a Supplement: Volume 14 Supplement 6

  12. Canker disease caused by Neoscytalidium dimidiatum is the most serious disease that attacks the pitaya industry. One pathogenic fungus, referred to as ND8, was isolated from the wild-type red-fleshed pitaya (Hylo...

    Authors: Min Xu, Cheng-Li Liu, Juan Luo, Zhao Qi, Zhen Yan, Yu Fu, Shuang-Shuang Wei and Hua Tang
    Citation: BMC Genomics 2019 20:10
    Content type: Research article Published on:

  13. Secreted modular calcium binding protein-1 (Smoc-1) belongs to the BM-40 family which has been implicated with tissue remodeling, angiogenesis and bone mineralization. Besides its anticipated role in embryogenesi...

    Authors: Jyoti Srivastava, Sanjay Premi, Sudhir Kumar, Iqbal Parwez and Sher Ali
    Citation: BMC Genomics 2007 8:436
    Content type: Research article Published on:

  14. In the mammary gland, local recruitment and action of macrophages is a key immunological defence mechanism against infection. Macrophages are members of the innate immune system, serve as the first line of the...

    Authors: Anna Monika Lewandowska-Sabat, Guro Margrethe Boman, Alison Downing, Richard Talbot, Anne Kristine Storset and Ingrid Olsaker
    Citation: BMC Genomics 2013 14:891
    Content type: Research article Published on:

  15. Although banana (Musa sp.) is an important edible crop, contributing towards poverty alleviation and food security, limited transcriptome datasets are available for use in accelerated molecular-based breeding in ...

    Authors: Marco A N Passos, Viviane Oliveira de Cruz, Flavia L Emediato, Cristiane Camargo de Teixeira, Vânia C Rennó Azevedo, Ana C M Brasileiro, Edson P Amorim, Claudia F Ferreira, Natalia F Martins, Roberto C Togawa, Georgios J Pappas Júnior, Orzenil Bonfim da Silva Jr and Robert NG Miller
    Citation: BMC Genomics 2013 14:78
    Content type: Research article Published on:

  16. Oxidative stress is a consequence of normal and abnormal cellular metabolism and is linked to the development of human diseases. The effective functioning of the pathway responding to oxidative stress protects...

    Authors: Sriram Sridharan, Ritwik Layek, Aniruddha Datta and Jijayanagaram Venkatraj
    Citation: BMC Genomics 2012 13(Suppl 6):S4
    Content type: Research Published on:

    This article is part of a Supplement: Volume 13 Supplement 6

  17. The serine carboxypeptidase-like protein (SCPL) family plays a vital role in stress response, growth, development and pathogen defense. However, the identification and functional analysis of SCPL gene family memb...

    Authors: Xiaomin Xu, Lili Zhang, Wan Zhao, Liang Fu, Yuxuan Han, Keke Wang, Luyu Yan, Ye Li, Xiao-Hong Zhang and Dong-Hong Min
    Citation: BMC Genomics 2021 22:350
    Content type: Research Published on:

  18. Hypoxia mediated pulmonary hypertension (HPH) is a lethal disease and lacks effective therapy. CircRNAs play significant roles in physiological process. Recently, circRNAs are found to be m6A-modified. The abunda...

    Authors: Hua Su, Guowen Wang, Lingfang Wu, Xiuqing Ma, Kejing Ying and Ruifeng Zhang
    Citation: BMC Genomics 2020 21:39
    Content type: Research article Published on:

  19. The growth and development of skeletal muscle directly impacts the quantity and quality of pork production. Chinese indigenous pig breeds and exotic species vary greatly in terms of muscle production and perfo...

    Authors: Yuqiang Zhao, Ji Li, Huijing Liu, Yu Xi, Ming Xue, Wanghong Liu, Zhenhua Zhuang and Minggang Lei
    Citation: BMC Genomics 2015 16:377
    Content type: Research article Published on:

  20. While an increase in bone marrow adiposity is associated with age-related bone disease, the function of bone marrow adipocytes has not been studied. The aim of this study was to characterize and compare the ag...

    Authors: Li-Fen Liu, Wen-Jun Shen, Masami Ueno, Shailja Patel and Fredric B Kraemer
    Citation: BMC Genomics 2011 12:212
    Content type: Research article Published on:

  21. Waterlogging is one of the main abiotic stresses that limit wheat production. Quantitative proteomics analysis has been applied in the study of crop abiotic stress as an effective way in recent years (e.g. sal...

    Authors: Rui Pan, Dongli He, Le Xu, Meixue Zhou, Chengdao Li, Chu Wu, Yanhao Xu and Wenying Zhang
    Citation: BMC Genomics 2019 20:60
    Content type: Research article Published on:

  22. Outbreaks of the casuarina moth, Lymantria xylina Swinehoe (Lepidoptera: Lymantriidae), which is a very important forest pest in Taiwan, have occurred every five to 10 years. This moth has expanded its range of h...

    Authors: Yu-Shin Nai, Chih-Yu Wu, Tai-Chuan Wang, Yun-Ru Chen, Wei-Hong Lau, Chu-Fang Lo, Meng-Feng Tsai and Chung-Hsiung Wang
    Citation: BMC Genomics 2010 11:116
    Content type: Research article Published on:

  23. Taxus cells are a potential sustainable and environment-friendly source of taxol, but they have low survival ratios and slow grow rates. Despite these limitations, Taxus callus cells induced through 6 months of c...

    Authors: Ying Chen, Meng Zhang, Xiaofei Jin, Haoran Tao, Yamin Wang, Bo Peng, Chunhua Fu and Longjiang Yu
    Citation: BMC Genomics 2020 21:168
    Content type: Research article Published on:

  24. Independent lines of evidence suggested that a large fraction of human genes possess multiple promoters driving gene expression from distinct transcription start sites. Understanding which promoter is employed...

    Authors: Gregory AC Singer, Jiejun Wu, Pearlly Yan, Christoph Plass, Tim HM Huang and Ramana V Davuluri
    Citation: BMC Genomics 2008 9:349
    Content type: Research article Published on:

  25. Cryptic genetic variation (CGV) is the hidden genetic variation that can be unlocked by perturbing normal conditions. CGV can drive the emergence of novel complex phenotypes through changes in gene expression....

    Authors: Basten L. Snoek, Mark G. Sterken, Roel P. J. Bevers, Rita J. M. Volkers, Arjen van’t Hof, Rachel Brenchley, Joost A. G. Riksen, Andrew Cossins and Jan E. Kammenga
    Citation: BMC Genomics 2017 18:500
    Content type: Research article Published on:

  26. The unprecedented role of sncRNAs in the regulation of pollen biogenesis on both transcriptional and epigenetic levels has been experimentally proven. However, little is known about their global regulation, es...

    Authors: Kamila Lucia Bokszczanin, Nicolas Krezdorn, Sotirios Fragkostefanakis, Sören Müller, Lukas Rycak, Yuanyuan Chen, Klaus Hoffmeier, Jutta Kreutz, Marine J. Paupière, Palak Chaturvedi, Rina Iannacone, Florian Müller, Hamed Bostan, Maria Luisa Chiusano, Klaus-Dieter Scharf, Björn Rotter…
    Citation: BMC Genomics 2015 16:714
    Content type: Research article Published on:

  27. Soybean mosaic disease caused by soybean mosaic virus (SMV) is one of the most devastating and widespread diseases in soybean producing areas worldwide. The WRKY transcription factors (TFs) are widely involved in...

    Authors: Zhihua Zhao, Rongna Wang, Weihua Su, Tianjie Sun, Mengnan Qi, Xueyan Zhang, Fengju Wei, Zhouliang Yu, Fuming Xiao, Long Yan, Chunyan Yang, Jie Zhang and Dongmei Wang
    Citation: BMC Genomics 2024 25:620
    Content type: Research Published on:

  28. Di-(2-ethylhexyl)-phthalate (DEHP) is a commonly used plasticizer in polyvinylchloride (PVC) formulations and a potentially non-genotoxic carcinogen. The aim of this study was to identify genes whose level of ...

    Authors: Yann Landkocz, Pascal Poupin, Franck Atienzar and Paule Vasseur
    Citation: BMC Genomics 2011 12:524
    Content type: Research article Published on:

  29. Genome wide association studies (GWAS) have revealed a large number of links between genome variation and complex disease. Among other benefits, it is expected that these insights will lead to new therapeutic ...

    Authors: Chen Cao and John Moult
    Citation: BMC Genomics 2014 15(Suppl 4):S5
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 4

  31. Enterococcus faecalis is widely studied as a common gut commensal and a nosocomial pathogen. In fact, Enterococcus faecalis is ubiquitous in nature, and it has been isolated from various niches, including the gas...

    Authors: Qiuwen He, Qiangchuan Hou, Yanjie Wang, Jing Li, Weicheng Li, Lai-Yu Kwok, Zhihong Sun, Heping Zhang and Zhi Zhong
    Citation: BMC Genomics 2018 19:527
    Content type: Research article Published on:

  32. Microarray normalizations typically apply methods that assume absence of global transcript shifts, or absence of changes in internal control features such as housekeeping genes. These normalization approaches ...

    Authors: Carole L Yauk, Andrew Williams, Sherri Boucher, Lynn M Berndt, Gu Zhou, Jenny L Zheng, Andrea Rowan-Carroll, Hongyan Dong, Iain B Lambert, George R Douglas and Craig L Parfett
    Citation: BMC Genomics 2006 7:266
    Content type: Methodology article Published on:

  33. Foraging behavior in honey bees (Apis mellifera) is a complex phenotype that is regulated by physiological state and social signals. How these factors are integrated at the molecular level to modulate foraging be...

    Authors: Rong Ma, Juliana Rangel and Christina M. Grozinger
    Citation: BMC Genomics 2019 20:592
    Content type: Research article Published on:

  34. Rice blast is the most threatening disease to cultivated rice. Magnaporthe oryzae, its causal agent, is likely to encounter environmental challenges during invasive growth in its host plants that require shifts i...

    Authors: Sandra M Mathioni, André Beló, Christopher J Rizzo, Ralph A Dean and Nicole M Donofrio
    Citation: BMC Genomics 2011 12:49
    Content type: Research article Published on:

  35. CCCH zinc finger proteins contain a typical motif of three cysteines and one histidine residues and serve regulatory functions at all stages of mRNA metabolism. In plants, CCCH type zinc finger proteins compri...

    Authors: Guohua Chai, Ruibo Hu, Dongyuan Zhang, Guang Qi, Ran Zuo, Yingping Cao, Peng Chen, Yingzhen Kong and Gongke Zhou
    Citation: BMC Genomics 2012 13:253
    Content type: Research article Published on:

  36. Though it is toxic to humans, dichlorvos is a widely used chemical pesticide and plays an important role in the control of plant pests. The application of a combination of the biocontrol agent Trichoderma with di...

    Authors: Qiong Wu, Mi Ni, Guisheng Wang, Qianqian Liu, Meixia Yu and Jun Tang
    Citation: BMC Genomics 2018 19:596
    Content type: Research article Published on:

  37. Lipopolysaccharide (LPS) is a cell wall component of Gram-negative bacteria with proved role in pathogenesis of sepsis. Brain injury was observed with both patients dead from sepsis and animal septic models. H...

    Authors: Gang Yue, Guanfang Shi, Marco A Azaro, Qifeng Yang, Guohong Hu, Minjie Luo, Kingsley Yin, Robert G Nagele, Daniel H Fine, Jin-Ming Yang and Honghua Li
    Citation: BMC Genomics 2008 9:608
    Content type: Research article Published on:

  39. Chromosomes are organized into units called topologically associated domains (TADs). TADs dictate regulatory landscapes and other DNA-dependent processes. Even though various factors that contribute to the spe...

    Authors: Benjamin Soibam and Ayzhamal Zhamangaraeva
    Citation: BMC Genomics 2021 22:397
    Content type: Research Published on:

  40. The ability to imitate the vocalizations of other organisms, a trait known as vocal learning, is shared by only a few organisms, including humans, where it subserves the acquisition of speech and language, and...

    Authors: Peter V. Lovell, Nicole A. Huizinga, Samantha R. Friedrich, Morgan Wirthlin and Claudio V. Mello
    Citation: BMC Genomics 2018 19:231
    Content type: Research article Published on:

  41. Genomes of gram-positive bacteria encode many putative cell-surface proteins, of which the majority has no known function. From the rapidly increasing number of available genome sequences it has become apparen...

    Authors: Roland Siezen, Jos Boekhorst, Lidia Muscariello, Douwe Molenaar, Bernadet Renckens and Michiel Kleerebezem
    Citation: BMC Genomics 2006 7:126
    Content type: Research article Published on:

  42. The combination of chromatin immunoprecipitation with two-channel microarray technology enables genome-wide mapping of binding sites of DNA-interacting proteins (ChIP-on-chip) or sites with methylated CpG di-n...

    Authors: Michiel E Adriaens, Magali Jaillard, Lars MT Eijssen, Claus-Dieter Mayer and Chris TA Evelo
    Citation: BMC Genomics 2012 13:42
    Content type: Research article Published on:

  43. Information about the composition of regulatory regions is of great value for designing experiments to functionally characterize gene expression. The multiplicity of available applications to predict transcrip...

    Authors: Enrique Blanco and Montserrat Corominas
    Citation: BMC Genomics 2012 13:688
    Content type: Software Published on:

  44. The analysis of expression quantitative trait loci (eQTL) is a potentially powerful way to detect transcriptional regulatory relationships at the genomic scale. However, eQTL data sets often go underexploited ...

    Authors: Jacob J Michaelson, Rudi Alberts, Klaus Schughart and Andreas Beyer
    Citation: BMC Genomics 2010 11:502
    Content type: Methodology article Published on:

  45. Prion diseases are characterized by the accumulation of the pathogenic PrPSc protein, mainly in the brain and the lymphoreticular system. Although prions multiply/accumulate in the lymph nodes without any detecta...

    Authors: Hicham Filali, Inmaculada Martín-Burriel, Frank Harders, Luis Varona, Carlos Hedman, Diego R Mediano, Marta Monzón, Alex Bossers, Juan J Badiola and Rosa Bolea
    Citation: BMC Genomics 2014 15:59
    Content type: Research article Published on:

  46. The understanding of whole genome sequences in higher eukaryotes depends to a large degree on the reliable definition of transcription units including exon/intron structures, translated open reading frames (OR...

    Authors: Matthias B Wahl, Randolph B Caldwell, Andrzej M Kierzek, Hiroshi Arakawa, Eduardo Eyras, Nina Hubner, Christian Jung, Manuel Soeldenwagner, Manuela Cervelli, Yan-Dong Wang, Volkmar Liebscher and Jean-Marie Buerstedde
    Citation: BMC Genomics 2004 5:98
    Content type: Research article Published on:

  47. Simple sequence repeats (SSRs) of GACA/GATA have been implicated with differentiation of sex-chromosomes and speciation. However, the organization of these repeats within genomes and transcriptomes, even in th...

    Authors: Jyoti Srivastava, Sanjay Premi, Sudhir Kumar and Sher Ali
    Citation: BMC Genomics 2008 9:132
    Content type: Research article Published on:

  48. Soil salinization is a major limiting factor for crop cultivation. Switchgrass is a perennial rhizomatous bunchgrass that is considered an ideal plant for marginal lands, including sites with saline soil. Here...

    Authors: Pan Zhang, Tianqi Duo, Fengdan Wang, Xunzhong Zhang, Zouzhuan Yang and Guofu Hu
    Citation: BMC Genomics 2021 22:82
    Content type: Research article Published on:

  49. Chromatin immunoprecipitation (ChIP) is an antibody-based approach that is frequently utilized in chromatin biology and epigenetics. The challenge in experimental variability by unpredictable nature of usable ...

    Authors: Ariel Caride, Jin Sung Jang, Geng-Xian Shi, Sam Lenz, Jian Zhong, Kwan Hyun Kim, Mariet Allen, Keith D. Robertson, Gianrico Farrugia, Tamas Ordog, Nilüfer Ertekin-Taner and Jeong-Heon Lee
    Citation: BMC Genomics 2023 24:171
    Content type: Research article Published on:

  50. Previously, drug-based synchronization procedures were used for characterizing the cell cycle dependent transcriptional program. However, these synchronization methods result in growth imbalance and alteration...

    Authors: Vince Kornél Grolmusz, Eszter Angéla Tóth, Kornélia Baghy, István Likó, Ottó Darvasi, Ilona Kovalszky, János Matkó, Károly Rácz and Attila Patócs
    Citation: BMC Genomics 2016 17:412
    Content type: Research article Published on:

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